{"data":[{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":55,"idioma_id":5,"titulo":"PENSAR LA LENTIFICACIÓN DE LAS TRAYECTORIAS ESTUDIANTILES UNIVERSITARIAS DESDE LA REFLEXIVIDAD BOURDIANA. UN ESTUDIO SOBRE LA UNIVERSIDAD NACIONAL DE SAN JUAN","resumen":"El artículo que aquí presentamos, si bien comparte el interés general sobre el devenir de las trayectorias de estudiantes en las instituciones universitarias de gestión estatal, abordado por un número cada vez mayor de estudiosos dedicados al tema, procura desarrollar una visión analítica productiva que permita capturar algunos rasgos de la especificidad del fenómeno en torno a una institución universitaria estatal en particular: la Universidad Nacional de San Juan. Se visibiliza así una línea de investigación que se viene consolidando en la provincia desde hace varios años, espacio académico en el que los autores de este trabajo participan como investigadores.En particular, se trata de analizar el fenómeno de lentificación de las trayectorias académicas estudiantiles. Esto es, cuando el recorrido académico efectuado por los estudiantes universitarios desde su ingreso hasta su graduación o abandono, demanda un tiempo considerablemente superior a lo estipulado según los planes de estudios correspondientes a cada carrera.","palabras_clave":"Trayectoria |académica|Universidad|Estudiantes"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":83,"idioma_id":4,"titulo":"Computer-Aided Recognition of ABC Transporters Substrates and Its Application to the Development of New Drugs for Refractory Epilepsy","resumen":"Despite the introduction of more than 15 third generation antiepileptic drugs to the market from 1990 to the moment, about one third of the epileptic patients still suffer from refractory of intractable epilepsy. Several hypotheses seek to explain the failure of drug treatments to control epilepsy symptoms in such patients. The most studied one proposes that drug resistance might be related with regional overactivity of efflux transporters from the ATP-Binding Cassette (ABC) superfamily at the blood-brain barrier and\/or the epileptic foci in the brain. Different strategies have been conceived to address the transporter hypothesis, among them inhibiting or down-regulating the efflux transporters or bypassing them through a diversity of artifices. Here, we review the computer-assisted early recognition of ABC transporters substrates as an interesting strategy to develop novel antiepileptic drugs capable of treating refractory epilepsy linked to ABC transporters overactivity.","palabras_clave":"REFRACTORY EPILEPSY|ANTIEPILEPTIC DRUGS|DRUG DISCOVERY|ABC TRANSPORTERS|TRANSPORTER HYPOTHESIS|P-GLYCOPROTEIN|BREAST CANCER RESISTANCE PROTEIN|ABCG2|ABCB1"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":111,"idioma_id":5,"titulo":"Algoritmos de punto de cambio para la detección de estructuras vorticosas en campos fluidodinamicos turbulentos","resumen":"En este trabajo se presenta la aplicación y análisis del empleode algoritmos numéricos de modelos para la detección de los cambios enuna señal de flujo turbulento obtenida a partir de medicionesexperimentales, con el objeto de determinar la existencia de estructurasvorticosas presentes en un campo fluidodinamico. Para el estudio de estaaplicación se utilizan mediciones basadas en anemometría de hilocaliente, considerando a las componentes fluctuantes de la velocidad delaire en un punto específico. De la muestra de datos obtenidos se analizala aplicación del modelo de un algoritmo de punto de cambio (CPM), con elfin de determinar los posibles cambios de la fluctuación de la velocidad,comparando los resultados con los análisis tradicionales.Se emplean algoritmos que logran detectar cambios en datos que nopresenten una distribución estadística conocida, como es el caso deseñales de flujo turbulento.Se presentan casos testigos conocidos para lograr establecer laaplicabilidad del algoritmo. Luego se muestra su aplicación a una señalde velocidad correspondiente a desprendimientos periódicos aguas abajo deun dispositivo de control de flujo (mini flap de Gurney) en el borde defuga de un perfil aerodinámicoDe los resultados obtenidos se desprende que el modelo planteado presentauna buena concordancia con las detecciones esperadas, mostrando ser unabuena herramienta alternativa para el análisis de estos tipos deflujo.\/In this paper the application and analysis of the use of changepoint model algorithms for changes detection in a turbulent flow signalobtained from experimental measurements is presented. In order todetermine the existence of vortex structures in a turbulent flow field.To study this application, hot wire anemometry measurements are used,considering the fluctuating components of velocity of the air at aspecific point. From a data sample a change point model (CPM) algorithmswas applied, in order to determine possible changes of the velocityfluctuation, comparing the results with traditional analysis.Algorithms, to detect changes in data which belongs of a not knownstatistical distribution, such as turbulent flow of signals, are used.Test known cases are presented to establish the applicability of thealgorithm. Then the algorithm is applied to a known periodic detachmentspeed signal downstream a flow control device (mini Gurney flap) in thetrailing edge of an airfoil.From the results it follows that the proposed model shows good agreementwith the expected detections, showing a good alternative tool for theanalysis of these types of flow.","palabras_clave":"TURBULENCIA|ESCALA TEMPORAL|FRECUENCIA CARACTERISTICA|ALGORITMO DE DETECCION|PUNTO DE CAMBIO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":114,"idioma_id":4,"titulo":"Estimated population size of two South American sea lion male haulouts from the northern coast of Argentina","resumen":"Knowledge of the real size of any wild population is an essential tool to take management and conservation measures and even more so when the population studied may have potential conflicts with humans.Because of this, the objective of this study was to estimate the population size of two South American sea lion male haul-outs using mark-resighting techniques. The results showed that on average, the estimated total number of animals tripled the number of animals recorded by direct counting. These findings demonstrate that it is necessary to continue researching population estimate methods to apply when taking conservation measuresin the future.","palabras_clave":"ARGENTINA|MARK-RESIGHTING|NOREMARK|OTARIA FLAVESCENS|PINNIPEDS|POPULATION ESTIMATES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":153,"idioma_id":5,"titulo":"El periódico anarquista Nuestra Tribuna. Un diálogo transnacional en América Latina","resumen":"El presente artículo se inscribe en el marco del fuerte impacto del enfoque transnacional en la historiografía de América Latina y en los estudios sobre el anarquismo. Particularmente, sigue la línea de los trabajos que analizan la prensa anarquista como soporte de las redes trasnacionales. Un objetivo más específico está relacionado con el caso particular del periódico Nuestra Tribuna.","palabras_clave":"ANARQUISMO|PRENSA ANARQUISTA|REDES TRANSNACIONALES|AMÉRICA LATINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":160,"idioma_id":4,"titulo":"Methodology for the estimation of the age categories of Hydrochoerus hydrochaeris (Rodentia, Hydrochoeridae) through the cranial and femur morphometry","resumen":"The aim of this study is to propose a methodologyto estimate the age of individuals of capybaras(Hydrochoerus hydrochaeris) using some morphometricmeasurements of the skull and femur. A sample of 250individuals from different age categories was analyzed.These categories were estimated based on the ossificationdegree of the cranial sutures. Out of 28 morphocranialmeasurements taken, nine of them allow us to adequatelydetermine the degree of bone maturation and the relativeage: pre maxillonasal maximum width (MNW), pre maxillonasalminimum width (MNMW), parietal width (PW),intermaxillary width (IMW), maximum width of the 3rdmolar (MW), minimum width of the 3rd molar (MMW),3rd molar length (M3), molar length, and molar 1 and 2length (M12). In case of the femur, the measurements didnot show differences among age categories, thus, we discardedthese morphometric magnitudes as possible ageindicators. This work proposes new measures to estimateand to analyze the relative age structure of the capybarapopulation, providing a useful tool in the management and conservation of this species, and to evaluate paleontologicaland archaeological assemblages.","palabras_clave":"Age estimation|Capybara|Morphometric measurements|Skulls"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":178,"idioma_id":4,"titulo":"Forbidden induced subgraphs of normal Helly circular-arc graphs: Characterization and detection","resumen":"A normal Helly circular-arc graph is the intersection graph of a set of arcs on a circle of which no three or less arcs cover the whole circle. Lin et al. (2013) characterized circular-arc graphs that are not normal Helly circular-arc graphs, and used them to develop the first recognition algorithm for this graph class. As open problems, they ask for the forbidden subgraph characterization and a direct recognition algorithm for normal Helly circular-arc graphs, both of which are resolved by the current paper. Moreover, when the input is not a normal Helly circular-arc graph, our recognition algorithm finds in linear time a minimal forbidden induced subgraph as a certificate. Our approach yields also a considerably simpler algorithm for the certifying recognition of proper Helly circular-arc graphs, a subclass of normal Helly circular-arc graphs.","palabras_clave":"Certifying algorithms|Linear-time; (proper) interval graphs|Chordal graphs; (minimal) forbidden induced subgraphs|Holes; (normal, Helly, proper) circular-arc models"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":183,"idioma_id":4,"titulo":"The maximum-impact coloring polytope","resumen":"Given two graphs $G=(V,E_G)$ and $H=(V,E_H)$ over the same set of vertices and given a set of colors $C$, the emph{impact on $H$} of a coloring $c:Vo C$ of $G$, denoted $imp(c)$, is the number of edges $ijin E_H$ such that $c(i) = c(j)$. In this setting, the emph{maximum-impact coloring} problem asks for a proper coloring of $G$ maximizing the impact $imp(c)$ on $H$. This problem naturally arises in the assignment of classrooms to courses, where it is desirable --but not mandatory-- to assign lectures from the same course to the same classroom. Since the maximum-impact coloring problem is NP-hard, we propose in this work an integer-programming-based approach for tackling this problem. To this end, we present an integer programming formulation and we study the associated polytope. We provide several families of valid inequalities, and we study under which conditions these inequalities define facets of the associated polytope. Finally, we show computational evidence over real-life instances suggesting that some of these families may be useful in a cutting-plane environment.","palabras_clave":"coloring|integer programming|facets"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":218,"idioma_id":5,"titulo":"Naturales, vecinos y extranjeros en el ejercicio de cargos públicos y oficios. Buenos Aires (ciudad y campaña), 1812-1815","resumen":"    En este artículo nos proponemos analizar  la situación jurídica y política de los extranjeros que ocupaban cargos  públicos y ejercían oficios en el Río de la Plata entre 1812 y 1815, a partir  de documentos originales de la época. Demostramos que los derechos del natural  y de vecino fueron los principales ejes sobre los que se continuaron planteando  las prácticas políticas. En Buenos Aires, las cartas de ciudadanía se otorgaban  discrecionalmente según lo resuelto por las autoridades y de acuerdo con las  necesidades de la revolución.  ","palabras_clave":"Ciudadanía|Revolución de Mayo|Naturaleza|Cargos Públicos"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":290,"idioma_id":4,"titulo":"Current State and Future Perspectives in QSAR Models to Predict Blood Brain Barrier penetration in Central Nervous System Drug R&D","resumen":"The blood brain barrier (BBB) is a physical and biochemical barrier that restricts the entry of certain drugs to the Central Nervous System (CNS), while allowing the passage of others. The ability to predict the permeability of a given molecule through the BBB is a key aspect in CNS drug discovery and development, since neurotherapeutic agents with molecular targets in the CNS should be able to cross the BBB, whereas peripherally acting agents should not, to minimize the risk of CNS adverse effects. In this review we examine and discuss QSAR approaches and current availability of experimental data for the construction of BBB permeability predictive models, focusing on the modeling of the biorelevant parameter unbound partitioning coefficient (Kp,uu). Emphasis is made on two possible strategies to overcome the current limitations of in silico models: considering the prediction of brain penetration as a multifactorial problem, and increasing experimental datasets through accurate and standardized experimental techniques.","palabras_clave":"QSAR|IN SILICO MODELS|BBB|Kpuu|BRAIN PENETRATION|CENTRAL NERVOUS SYSTEM"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":300,"idioma_id":4,"titulo":"Quantitative food webs and invertebrates assemblages of a large River: a spatiotemporal approach in floodplain shallow lakes","resumen":"n order to identify the  spatiotemporal  variation in the use of trophic resources and  food web 21 attributes, we described the structure and composition of communities and examined the  food 22 web in two shallow lakes over three hydrometric levels using the stomach contents of fishes and 23 decapods.  The  communities  are  more  similar  temporally,  while  the  food  webs  are  clustered 24 spatially. The drought phase was the most divergent in both cases with dominance of mussels and 25 prawns in the communities. The spatial variations of food web attributes are the result of higher 26 connectance and nestedness in the directly connected lake. Predators consumed macrophytes over 27 all hydroperiods though this predation was most intense during flooding pulse. Detritus was of 28 the greatest importance during the transition phase, while the use of basal resources was more 29 equitable during the drought period. Among invertebrates, the magnitude of trophic interactions 30 varied  from the consumption of  mayflies and  midges  in the flooding and transition phases to 31 mollusks, copepods and prawns  in the dry season. The high consumption of  macrophytes and 32 abundant invertebrates suggest the importance of autochthonous inputs into food webs and that 33 variation in food supply is a key factor for food web structure.","palabras_clave":"Paraná River  |bipartite networks|hydrological regime|communities|webmetrics"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":389,"idioma_id":4,"titulo":"Cytogenetic markers for the characterization of Capsicum annuum L. cultivars","resumen":"Karyotypic studies with conventional staining have been unsuccessful due to the uniformity of Capsicum chromosomes. In this study, we found diagnostic chromosome characters that permit to characterize cultivars; this is the first cytological characterization of both rDNAs (18S and 5S) in a species of Capsicum using a genus specific probe and the most exhaustive in C. annuum to date. The heterochromatic  banding patterns enabled us to identify cultivars, and fluorescent in situ hybridization (FISH) showed one 5S rDNA locus largely conserved within the cultivars, whereas high variation in the number of 18S rDNA loci was observed. One of the most obvious differences is the presence of an additional active nucleolar organizer region in pair #12 and the dispersal of inactive 18S rDNA signals. These results indicate that fluorochrome banding together with silver impregnation and FISH procedures are very useful for the identification of chromosomes and the interpretation of chromosomal variation between cultivars. The functional role of this variation is still uncertain, but our results show that copy number variation of repetitive DNA during the course of evolution might provide an excellent experimental system for studying genome rearrangements accompanying functional divergence in domesticated C. annuum.","palabras_clave":"Capsicum annuum|ribosomal DNA|FISH|fluorochrome banding|silver staining"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":391,"idioma_id":4,"titulo":"Synthesis and characterization of SBA-15 modified with alkali metals","resumen":"The promotion of the mesoporous solid SBA-15 with different alkaline cations (Li, K and Cs) has been studied. X-ray diffraction at low angles, Nitrogen adsorption at 77 K, Electron transmission microscopy, X-ray photoelectron spectroscopy, atomic absorption spectroscopy and Thermal Programmed Desorption of carbon dioxide were used to characterize the solids. The introduction of alkali metals within the channels of the solid generates basic sites of weak and intermediate strength, which do not exist in undoped SBA-15. Besides, the presence of these ions did not change the structural and textural properties of the original support, only a densification of the channel walls is evidenced. According to the alkali metal used, the order established by the total number of sites obtained is: Li-SBA-15>> K-SBA-15 &#8776; Cs-SBA-15, while the order by strength of both types of sites (weak and intermediate) is: Li-SBA-15> Cs-SBA-15> K-SBA-15. These results may lead to the advance in the understanding of the basic sites role in the field of mesoporous materials.","palabras_clave":"ALKALINE CATIONS|BASICITY|MESOPOROUS MATERIALS|SURFACE PROPERTIES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":809,"idioma_id":4,"titulo":"OPTIMIZATION OF BIOMASS AND ENDO-&#946;-1,4-GLUCANASE BY WHITE ROT FUNGI NATIVE FROM ARGENTINA","resumen":"A large number of microorganisms are capable of producing cellulases; however, fungi are considered among the most activeenzymes producers. Different strains of white rot fungi (WRF) were reported to have a great potential for biotechnologicalapplications and cellulase enzymes is much involved in this effect, especially for bioethanol production. Misiones is included in aforest region characterized by a vast biodiversity, and within this environment, a large number of microorganisms can be isolated,including numerous white rot fungi. In the present work, response surface methodology (RSM) was applied for the determinationof biomass and endo-&#946;-1,4-glucanase activity factors dependence from three Argentinean WRF in submerged cultures. RSM wascarried out with a Box-Behnken design using 3 variables, temperature (25, 29 and 33°C), incubation time (7, 10.5 and 14 days)and pH (3.5, 4.5 and 5.5) with three central points and 2 replications. The best conditions for enzymatic activity were achieved atmaximum level of temperature (33°C), low level of pH (3.5) and intermediate level of incubation time (10.5 h). We havepresented here, preliminary studies on biomass and enzyme production of three fungi. Our data show that we have not yetreached the optimal enzyme production conditions, so further experiments are needed to reach optimal conditions.","palabras_clave":"WHITE ROT FUNGI|CELLULASES|PRODUCTION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":1201,"idioma_id":5,"titulo":"Evaluación  Genética de Reproductores Holando Argentino","resumen":"A partir de 1998 la Asociación Criadores de Holando Argentino, mediante convenio con la Facultad de Ciencias Veterinarias de Tandil, introdujo la metodología BLUP Modelo Animal para la estimación de los valores genéticos para producción y tipo de los reproductores de la raza. Estos valores se publican anualmente en los meses de Febrero y Agosto. Las ventajas sobresalientes de la obtención de valores genéticos mediante esta metodología son: Permite la evaluación simultánea de toros y vacas; por lo tanto se tienen valores para las hembras de la población analizada. Tiene en cuenta los apareamientos dirigidos. Es decir, que al calcular la prueba de un toro a partir de los datos de sus hijas se puede tener en cuenta cuál es el mérito genético de sus madres, corrigiendo así el hecho de que las mejores vacas se inseminen con los mejores toros.  Aumenta la precisión del valor genético al incluir las relaciones de parentesco.","palabras_clave":"Evaluación Genética|Holando Argentino"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":2084,"idioma_id":4,"titulo":"Electronic Properties and Dissociative Photoionization of Thiocyanates, Part II. Valence and Shallow-core (Sulfur and Chlorine 2p) Regions of Chloromethyl Thiocyanate, CH2ClSCN","resumen":"A combination of Photoelectron Spectroscopy (PES) and synchrotron-based PhotoElectron-PhotoIon-Coincidence (PEPICO) spectra has been applied to investigate the electronic structure and the dissociative ionization of halomethyl thiocyantes in the valence and shallow-core S 2p and Cl 2p regions. Two simple and closely related derivatives, namely CCl3SCN and CCl2FSCN, have been analyzed to asses the role of halogen substitution in the electronic properties of thiocyanates. The He(I) photoelectron spectra are assigned with the assistance of quantum chemical calculations at the outer-valence Green's function (OVGF) level of approximation. The first ionization energies observed at 10.55 and 10.78 eV for CCl3SCN and CCl2FSCN respectively, are assigned to the ionization process from the sulfur lone pair orbital [n(S)]. When these molecules are compared with CX3SCN (X = H, Cl, F) species, a linear relationship between the vertical first ionization energy and electronegativity of CX3 group is observed. Irradiation of CCl3SCN and CCl2FSCN with photons in the valence energy regions leads to the formation of CCl2X+ and CClXSCN+ (X = Cl or F) ions. Furthermore, the total ion yield spectra and the fragmentation patterns deduced from the PEPICO spectra are obtained in the S 2p and Cl 2p regions and several dissociation channels are determined for the core-excited species by using the triple coincidence PEPIPICO (PhotoElectron-PhotoIon-PhotoIon-Coincidence) spectra.","palabras_clave":"Electronic Properties |Dissociative Photoionization"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":2450,"idioma_id":4,"titulo":"Osteology of a perinatal aristonectine 2 (Plesiosauria; Elasmosauridae)","resumen":"Perinatal specimens give valuable information about the first stages of vertebrate ontogeny. Here, the morphology and palaeohistology of an aristonectine perinatal specimen from Seymour Island (Isla Marambio), López de Bertodano Formation are analysed. The palaeohistological analysis shows incomplete endochondral ossification (retention of a calcified cartilaginous core in the medullary region), predominance of primary bone tissue without secondary remodelling, lack of primary or secondary osteons and of growth marks in the cortical bone, and open vascular spaces not surrounded by a thin coat of lamellar bone tissue. General lines of morphological changes were inferred from comparing the fossil with an adult aristonectine specimen indicating i) a tendency of relatively high and broad posterior cervicals to decrease during ontogeny, ii) a decrease of relative size of the dorsolateral process and an increase of the glenoid ramus and iii) the existence of two separate stages in propodial growth divided into an initial elongation followed by a distal expansion. The presence of a perinatal specimen in the James Ross Archipelago indicates that the region was used as a breeding area by the aristonectines during the last part of the Cretaceous.","palabras_clave":"Aristonectinae|perinatal|Upper Cretaceous|Weddellian Province"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":2680,"idioma_id":5,"titulo":"Redes Políticas y Distribución de Recursos Públicos a nivel subnacional. Las relaciones provincia-municipios en el caso Córdoba, Argentina. (grupo 1 - Scopus)","resumen":"En los contextos post-descentralización, las relaciones intergubernamentales (RIGs) central-locales adquieren gran relevancia para comprender los procesos de asignación territorial de recursos públicos. La elevada autonomía local en la Provincia de Córdoba, Argentina, hace de ésta un caso apropiado para examinar la complejidad de factores involucrados en la distribución de recursos a municipios y, de este modo, generar aproximaciones heurísticas sobre estos procesos a nivel regional. Este estudio da cuenta de: a) la coexistencia de dos subsistemas de RIGs, a través de los cuales los gobiernos locales procuran acceder a recursos públicos de decisión discrecional, uno conformado por redes políticas formales y otro por una diversidad de redes políticas informales; b) se observa un efecto sistemático de ambos tipo de redes sobre las chances de acceso de los Gobiernos Locales a recursos de decisión discrecional del Gobierno Provincial; c) los Gobiernos Locales adoptan una estrategia combinada de vinculación a ambos tipos de redes, priorizando el mecanismo de la cohesión en las redes formales y la intermediación en las redes informales.","palabras_clave":"DISTRIBUCIÓN|REDES|RELACIONES INTERGUBERNAMENTALES|PARTIDOS POLÍTICOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":2697,"idioma_id":5,"titulo":"El palimpsesto como una puerta de acceso a diferentes temporalidades: el caso de Rio Las Salinas II (Tucuman, Argentina)","resumen":"En este trabajo discutimos la utilidad del concepto de palimpsesto como herramienta teóricometodológicaen la des-composición del paisaje arqueológico en unidades analíticas apropiadaspara la evaluación de la variabilidad en las historias de uso del espacio. Para ello se tuvieron encuenta indicadores de condiciones estabilidad a escalas del paisaje y los artefactos en Rio LasSalinas 2. Desde el paisaje, evaluamos procesos geomorfológicos de las superficies de glacis y elpavimento donde se encuentran depositados los conjuntos líticos. A nivel de artefactos tuvimosen cuenta análisis tipológicos de los artefactos, efectos de las alteraciones postdepositacionalesen las rocas (pátinas, abrasión eólica y fracturas) y tareas de ensamblaje. Los resultados nospermitieron detectar condiciones de mayor y menor estabilidad, asociadas a un pavimento congrados variables de madurez y sobre los que actúan procesos naturales que, en conjunto,repercuten sobre las condiciones de hallazgo del registro arqueológico. En un extremo, laestabilidad la asociamos a sectores donde el pavimento muestra cierto grado de preservación,con un correlato a escala del artefacto donde el barniz de las rocas y el ensamblaje ratifican estaestabilidad. En el extremo opuesto, detectamos condiciones de inestabilidad, marcadas porprocesos erosivos en sectores donde el pavimento está deteriorado o bien, no hay pavimento.Entre estos extremos hay una variedad de grises, donde encontramos evidencia de ambascondiciones, de estabilidad e inestabilidad, reflejadas en el cambio de las condiciones a las queestuvieron expuestos los materiales arqueológicos.","palabras_clave":"ESTABILIDAD DEL PAISAJE|CONJUNTOS ARTEFACTUALES LITICOS|ARQUEOLOGIA|GEOARQUEOLOGIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":2766,"idioma_id":4,"titulo":"In search of a lost village. Prospecting techniques at the site Mariano Miró (La Pampa Argentina, early twentieth century)","resumen":"Archeological research started in Mariano Miro (Chapaleufú, La Pampa, Argentina) site in 2011. In this sitethere are remains of a rural village, founded in 1901 by the railway station under the same name of theFerrocarril Oeste, with its header in Buenos Aires city. This village was inhabited by nearly 500 peopleand there was a series of shops typical of an agricultural-livestock occupation (stores, a baker´s shop, asmith house, etc.). Towards 1911 it had to be abandoned forcibly because its inhabitants could not renewtheir lease agreement over the lands they settled in. As from that moment, its owners destined that spaceto agricultural exploitation, and therefore no village structures were left standing.The Mariano Miro archaeological study is included in an investigation that aims at learning populationdynamics in the late nineteenth and early twentieth centuries. During those times, lands were incorporatedto the national territory after military campaigns against indigenous populations. This studypresents results obtained through different prospecting techniques applied to delimit the old villagecommon land. Although nowadays no surface structural remains are seen, the presence of a greatnumber of vitreous, ceramic and metallic fragments was recorded, from which a 240  140 m study areawas set. Over the whole surface of that area, covering 39,200 m2, transects were laid out; prospectingwas conducted with a metal detector and a systematic collection of surface material was made. Thediversity of data obtained was processed by Geographic Information System (GIS) which, together withARCGIS10 software, enabled us to correlate multiple variables. The use of documentary sources (aerialphotographs, cartography and village layout blueprints) helped identify site formation processes, oldburied structures and areas associated with specific social practices. The prospecting design applied letus guide archaeological interventions in such a large area and, based on the distribution and density ofthese findings, it helped differentiate sectors that would respond to deliberate social practices duringvillage occupation (e.g. dumps), from those that would be the result of post-depositional anthropic andnatural processes.","palabras_clave":"Prospección |SIG|recolección sistemática|distribución artefactual"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3423,"idioma_id":4,"titulo":"Speed of reversal from vecuronium neuromuscular block with different doses of neostigmine in anesthetized dogs","resumen":"Objectives Neostigmine is routinely used to reverse non-depolarizing neuromuscular block. Given its indirect mechanism, a plateau may exist whereby increasing doses of neostigmine do not result in clinical benefit. This study was designed to measure the speed of reversal of vecuronium-induced neuromuscular block in isoflurane-anesthetized dogs after the administration of three doses of neostigmine as used in clinical practice.Study design Prospective, crossover, randomized study. AnimalsSeven adult, mixed-breed dogs with a mean ± standard deviation (SD) age of 2.0 ± 0.8 years and weight of 19.1 ± 9.1 kg.MethodsDogs were anesthetized on three occasions with isoflurane and administered vecuronium (0.1 mg kg -1) intravenously (IV). The train-of-four (TOF) ratio was measured on the pelvic limb with acceleromyography. When the second twitch of the TOF had returned spontaneously, atropine (0.03 mg kg -1) and neostigmine (0.02, 0.04 or 0.07 mg kg -1) were administered IV. Time to reach a TOF ratio of &#8805;0.9 after neostigmine administration was recorded.ResultsIncreasing the dose of neostigmine from 0.02 mg kg -1 to 0.04 mg kg -1 and 0.07 mg kg -1 resulted in significant reductions in mean ± SD reversal times (10.5 ± 2.3, 7.4 ± 1.1 and 5.4 ± 0.5 minutes, respectively) (p < 0.0001) and smaller coefficients of variation (22%, 15% and 10%, respectively).Conclusions and clinical relevanceIncreasing the dose of neostigmine from 0.02 mg kg -1 to 0.04 mg kg -1 and 0.07 mg kg -1 produced faster and less variable reversal of vecuronium-induced neuromuscular block in isoflurane anesthetized dogs. No ceiling effect was observed at this dose range.","palabras_clave":"Keywords acceleromyography, cholinesterase inhibitor,"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3521,"idioma_id":4,"titulo":"Porcine sperm vitrification I: cryoloops method","resumen":"The aims of this study were to evaluate porcine sperm vitrification in cryoloops, with and without two different cryoprotectants and assess two warming procedures. Extended (n = 3; r = 4) and raw (n = 5; r = 2) semen was diluted in media without and with cryoprotectants (4% dimethylformamide and 4% glycerol) to a final concentration of 20 × 106 spermatozoa ml&#8722;1 and vitrified using the cryoloops method. Two warming procedures were evaluated: rapid method (30 s at 37°C) and an ultra-rapid method (7 s at 75°C, followed by 30 s at 37°C). Total motility (phase contrast), sperm viability (6-carboxifluorescein diacetate and propidium iodide stain), membrane function (hypo-osmotic swelling test), acrosome integrity (phase contrast), chromatin condensation (toluidine blue stain) and chromatin susceptibility to acid denaturation (acridine orange stain) were evaluated before and after vitrification and analysed using Friedman?s test. In all media, the only seminal parameters that were maintained after vitrification were chromatin condensation and integrity. Vitrification of porcine spermatozoon using cryoloops, both in the presence or absence of cryoprotectants and independent of the warming procedure used, permits conservation of sperm chromatin condensation and integrity. It would be interesting to further verify this by producing porcine embryos using vitrified spermatozoon with intracytoplasmic sperm injection.","palabras_clave":"CRYOLOOP|CRYOPRESERVATION|PORCINE|SEMEN|VITRIFICATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3722,"idioma_id":4,"titulo":"Titanium-hydroxyapatite composites sintered at low temperature for tissue engineering: in vitro cell support and biocompatibility","resumen":"Introduction: In clinical orthopedic, a critical problem is the bone tissue loss produced by a disease or injury and it is requires bone repairs and substitutes. The use of composites from titanium and hydroxyapatite for biomedical applications has increased due to the resulting advantageous combination of hydroxyapatite bioactivity and the favorable titanium mechanical properties. Powder metallurgy is a simple and lower cost method that uses powder from titanium and hydroxyapatite to obtain composites having hydroxyapatite phases in a metallic matrix. However, this method has certain limitations arising from thermal decomposition of hydroxyapatite in the titanium-hydroxyapatite system around 1200ºC. In this work, we obtained a composite from titanium and bovine hydroxyapatite sintered at 800°C and evaluated the in vitro biocompatibility according to ISO 10993 standard.Methods: The MTT assay was carried out to assess cytotoxicity on Vero and NIH3T3 cell lines. In addition, the cell morphology and cell adhesion on the composite surface were analyzed using fluorescence and SEM microscopy. Results: Our data did not reveal any toxicity of titanium-hydroxyapatite composite in epithelial Vero or fibroblastic NIH3T3 cells. Moreover, composite extracts did not affect the cell morphology or density. Finally, NIH3T3 cells were capable to adhere and proliferate on the composite surface. Conclusion: We obtained a composite with promising biomedical application through a simple method as powder metallurgy. Our results supplied in vitro proof of an adequate biocompatibility of titanium-hydroxyapatite composite when it sintered at a low temperature.&#8195;","palabras_clave":"Titanium|hydroxyapatite|composite|powder metallurgy"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3802,"idioma_id":4,"titulo":"The occurrence of Potamomyces palmarensis sp. nov. in the Late Holocene at the El Palmar National Park (Colón, Entre Ríos, Argentina) and transfer of fossil species of Mediaverrunites to Potamomyces","resumen":"We present in this contribution the first record of Potamomyces Hyde (Ascomycota, Dothideomycetidae) from soil sediments of the El Palmar National Park (PNEP), Entre Ríos, Argentina. Nineteen samples were taken (each 2-4 cm from the surface) of a log 80 cm thick core composed of a homogeneous lithology of argillaceous fine-grained sands. This taxon was only identified in the basal sample of the core (371 ± 30 years BP), located in a palm area (Butia yatay) with a semi-dense herbaceous-shrub layer. We propose an amendment of the generic diagnosis based on the revision of the up to now described species and of a new one here defined (P. palmarensis). Additionally, we confirm that the morphotaxon Mediaverrunites Jarzen & Elsik ex Nandi & A. Sinha is its junior synonym, so we propose new combinations for seven species. We do recommend the use of this natural taxon instead of the morphotaxon in future contributions. From the geographic and stratigraphic distribution of Potamomyces, our record is the first mentioned for Argentina and the southernmost for South America. Based on its ecological requirements, a humid sub-tropical environment and abundant organic matter in the soil are suggested for the Latest Holocene of the study region. This hypothesis is supported by current knowledge of regional climatic and environmental conditions for the study area during the short humid interval of the Little Ice Age.","palabras_clave":"Ascomycetes|Potamomyces|Mediaverrunites"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3866,"idioma_id":4,"titulo":"An asymmetric multi-item auction with quantity discounts applied to Internet service procurement in Buenos Aires public schools","resumen":"This article studies a multi-item auction characterized by asymmetric bidders and quantity discounts. We report a practical application of this type of auction in the procurement of Internet services to the 709 public schools of Buenos Aires. The asymmetry in this application is due to firms´ existing technology infrastructures, which affect their ability to provide the service in certain areas of the city. A single round first-price sealed-bid auction, it required each participating firm to bid a supply curve specifying a price on predetermined graduated quantity intervals and to identify the individual schools it would supply. The maximal intersections of the sets of schools each participant has bid on define regions we call competition units. A single unit price must be quoted for all schools supplied within the same quantity interval, so that firms cannot bid a high price where competition is weak and a lower one where it is strong. Quantity discounts are allowed so that the bids can reflect returns-to-scale of the suppliers and the auctioneer may benefit of awarding bundles of units instead of separate units. The winner determination problem in this auction poses a challenge to the auctioneer. We present an exponential formulation and a polynomial formulation for this problem, both based on integer linear programming. The polynomial formulation proves to find the optimal set of bids in a matter of seconds. Results of the real-world implementation are reported.","palabras_clave":"multi-item auction|asymmetric bidders|quantity discounts|integer linear programming"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3881,"idioma_id":4,"titulo":"Paleofloristic assemblage from the Paleogene Río Guillermo Formation, Argentina. Preliminary results of phylogenetic relationships of Nothofagus in South America","resumen":"Hünicken´s paleobotanical collection is one of the most important in South America because it was the firstone to be related to a documented stratigraphic profile. This floristic assemblage (Oligocene) recoveredfrom Río Guillermo Formation, at Estancia Tres Marías, Río Guillermo Valley, Santa Cruz, Argentina, isdescribed by the first time in this paper. Five species of genus Nothofagus (N. subferruginea, N. serrulata,N. crenulata, N. elongata and N. variabilis) together with Myrcia bagualense are components of theassemblage. The presence of Acaena brandmayri is confirmed for the first time for the area. Paleoenviromentaland paleoclimate implications are also discussed. Characteristic species from a temperate-cold climatesuch as the genus Nothofagus are present in the material studied. A phylogenetic study of the fossil speciesherein described and the extant South American species of Nothofagus is presented. The preliminaryresults support the hypothesis that fossil species of Nothogafus are closely related to the modern species.","palabras_clave":"Paleofloristic composition|Paleoclimate|Palaeoenvironmental|Nothofagus Phylogeny"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3890,"idioma_id":4,"titulo":"Vancomycin sensitized photooxidation in the presence of the natural pigment Vitamin B2. Interaction with excited states and photogenerated ROS","resumen":"Se adjunta resumen en .pdf","palabras_clave":"ANTIBIOTICS|VANCOMYCIN|PHOTOOXIDATION|RIBOFLAVIN|ROSE BENGAL|REACTIVE OXYGEN SPECIES|MICROBIOLOGICAL ASSAY|pH EFFECT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3897,"idioma_id":4,"titulo":"Structure of the Ru, Ag and Te L x-ray emission spectra","resumen":"Fe-L and Ni-L X-ray spectra induced by electron impact were analyzed. The measurements were made on bulk samples using a commercial wavelength dispersive spectrometer, and the spectra were processed with a parameter optimization method previously developed. This procedure allowed for the determination of characteristic energies, relative transition probabilities and natural linewidths. The results obtained are compared to the data found in the literature, when available. Satellite and radiative Auger emissions were also analyzed, energy shifts and relative intensities being determined. Many of these parameters were determined for the first time, which was possible due to the robustness of the spectral processing method used. The line profile introduced here takes into account the differential attenuation at both sides of the absorption edge.","palabras_clave":"inner atomic shell ionization|electron impact|x-ray emission"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3901,"idioma_id":4,"titulo":"Combination of Sunlight, Oxidants and Ce-doped TiO2 for Phenol Degradation","resumen":"The degradation of phenol was used as a model reaction to investigate the photocatalytic properties of cerium-doped (0.1 nominal atomic percent) TiO2 catalysts in the presence and in the absence of oxidants: persulfate (PS) or hydrogen peroxide (HP). Experiments were performed in batch reactors using either artificial light (ultraviolet or visible) or solar exposure during spring?summer seasons in La Plata City (34.90° S, 57.92° W, 15 MASL). The formation of hydroquinone, catechol, and p-benzoquinone was observed in all the experiments. Additionally, for the experiments with PS (with or without catalyst), evidence of the formation of dimers and trimers was found. Total degradation of phenol (250 &#956;M) was achieved with doped material and 7 mM of PS (two doses) after 3 h of solar exposure (HS UV, T = 2.9 ± 0.6 105 J m&#8722;2).","palabras_clave":"Photocatalysis |Doped titanium dioxide |Phenol|Solar exposure"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3932,"idioma_id":4,"titulo":"An archaeobotanical perspective in the study of inflorescence phytoliths of wild grasses from arid and semi-arid environments of Argentina","resumen":"Wild cereals have been harvested all over the world by hunter-gatherer with evidences as much in South America as in Australia, North America and Subsaharian Africa. In some places there are still used for human consumption. The goal of this paper is to document phytoliths in inflorescence axis, and inkernels\/inflorescences\/bracts of several native Argentinian wild grasses in order to get an archaeobotanical comparative referential for the analyses of residues from both food plant processing activities and consumption. We could observe typical phytolith morphotypes from specific anatomical parts of grasses, but non-taxon specific, as well as non-diagnostic phytolith morphotypes, but characteristic of the phytolith association of a certain taxa. They all allow us to get a more complete view of the phytolith production for each specific taxon. Results obtained by Morisita Test-Past Program-suggest a trend to the organization at the level of subfamilies for the phytoliths production in the 14 species studied. Species of the genus Aristida and Cynodon show an intra-generic consistency in the production of phytoliths morphotypes per organ, and tend to be grouped in cluster analysis. In some species as Cynodon dactylon, Bromus catharticus, Aristida adscensionis, Sorghastrum pellitum and Paspalum dilatatum it can be noted a similarity in the morphotype production as much in inflorescence axis as in kernels\/inflorescences\/bracts. A morphological continuum between similar morphotypes could be also established, by comparingseries of shapes within fragments of silicified plant tissue. Finally, we consider phytolith production from potential useful plant parts for human consumption, in a way as their presence alone, or associated with starch grain analyses, as showed by a previous work, could be used for regional dietary reconstructions. Our results from inflorescence\/kernel phytolith production give us good expectation to be able to identify them in archaeological contexts.","palabras_clave":"PHYTOLITHS|WILD GRASSES|SEMI-ARID ENVIRONMENTS|SOUTH AMERICA SOUTHERN CONE|KERNEL AND INFLORESCENCE|MORPHOLOGICAL CONTINUUM"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":3958,"idioma_id":4,"titulo":"The distribution of factorization patterns on linear families of polynomials over a finite field","resumen":"We estimate the number |A_&#955;| of elements on a linear family A of monic polynomials of Fq[T] of degree n having factorization pattern  &#955;:=1^{&#955;1}2^{&#955;2}&#8901;&#8901;&#8901;n^{&#955;n}. We show that |A_&#955;| = T(&#955;)q^{n-m} + O(q^{n-m-1\/2}), where T(&#955;) is the proportion of elements of the symmetric group of n elements with cycle pattern &#955; and m is the codimension of A. Furthermore, if the family A under consideration is 'sparse', then |A_&#955;|=T(&#955;)q^{n-m}+O(q^{n-m-1}). Our estimates hold for fields Fq of characteristic greater than 2. We provide explicit upper bounds for the constants underlying the O-notation in terms of &#955; and A with 'good' behavior. Our approach reduces the question to estimate the number of Fq-rational points of certain families of complete intersections defined over Fq. Such complete intersections are defined by polynomials which are invariant under the action of the symmetric group of permutations of the coordinates. This allows us to obtain critical information concerning their singular locus, from which precise estimates on their number of Fq-rational points are established.","palabras_clave":"FINITE FIELDS|FACTORIzATION PATTERNS |SYMMETRIC POLYNOMIALS|RATIONAL POINTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4028,"idioma_id":4,"titulo":"Development of cecal predominant microbiota in broilers during a complete rearing using denaturing gradient gel electrophoresis.","resumen":"Understanding of the intestinal microbiota is crucial to enhance intestinal health and performance parameters in animals. A more exhaustive research of the intestinal microbiota of broilers could be of interest to implement appropriate intervention measures. The aim of the present study was to investigate the development of the predominant cecal microbiota in broilers that were fed a Lactobacillus salivarius DSPV 001P strain during a complete rearing using denaturing gradient gel electrophoresis (DGGE). Bacterial DNA from cecal samples of 24 broilers at different ages were amplified by PCR and analysed by DGGE. A total of 35 DGGE products were excised and sequenced. Distinctive differences in bacterial communities were observed in the caecum as broilers age. At early stages, identified bacteria within the caecum of broilers were predominantly Clostridium-related species. Also, some sequences had the closest match to the genus Escherichia\/Shigella. Furthermore, the caecum was a reservoir rich in uncultured bacteria. The major difference observed in our study was an increase of potentially beneficial Lactobacillus at Day 45. These results may be attributed to modulation of the microbiota by the probiotic supplementation. The obtained data could be relevant for future studies related to the influence of the microbiota resulting from probiotic supplementation on the performance and the immunological parameters of broilers.","palabras_clave":"BACTERIAL COMMUNITIES|INTESTINAL HEALTH|LACTOBACILLUS SALIVARIUS|PROBIOTIC"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4031,"idioma_id":4,"titulo":"Biokinetics and tissue response to ultrananocrystalline diamond nanoparticles employed as coating for biomedical devices","resumen":"Although Ultrananocrystalline diamond (UNCD) has been proposed as a coating material for titanium biomedical implants, the biological effects and toxicity of UNCD particles that could eventually detach have not been studied to date. The biokinetics and biological effects of UNCD compared to titanium dioxide (TiO2) nanoparticles was evaluated in vivo using Wistar rats (n = 30) i.p. injected with TiO2, UNCD or saline solution. After 6 months, blood, lung, liver, and kidney samples were histologically analyzed. Oxidative damage by membrane lipidperoxidation (thiobarbituric acid reactive substances-TBARS), generation of reactive oxygen species (superoxide anion- O2 -), and antioxidant enzymes (superoxide dismutase-SOD, catalase-CAT) was evaluated in lung and liver. Histologic observation showed agglomerates of TiO2 or UNCD in the parenchyma of the studied organs, though there were fewer UNCD than TiO2 deposits. In addition, TiO2 caused areas compatibles with foci of necrosis in the liver and renal hyaline cylinders. Regarding UNCD, no membrane damage (TBARS) or mobilization of enzymatic antioxidants was observed either in lung or liver samples. No variations in O2 - generation were observed in lung (Co: 35.1 ± 4.02 vs. UNCD: 48 ± 9.1, p > 0.05). Conversely, TiO2 exposure caused production of O2 - in alveolar macrophages and consumption of catalase (p < 0.05). The studied parameters suggest that UNCD caused neither biochemical nor histological alterations, and therefore may prove useful as a surface coating for biomedical implants. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 2408?2415, 2017.","palabras_clave":"Titanium dioxide|ultrananocrystalline diamond nanoparticles|biockinetics|oxidative metabolism"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4099,"idioma_id":4,"titulo":"A rapid and simple method for the determination of psychoactive alkaloids by CE-UV: application to Peganum Harmala seed infusions","resumen":"The &beta;-carboline alkaloids of the harmala (HAlks) group are compounds widely spread in many natural sources, but found at relatively high levels in some specific plants like Peganum harmala (Syrian rue) or Banisteriopsis caapi. HAlks are a reversible Mono Amino Oxidase type A Inhibitor (MAOI) and, as a consequence, these plants or their extracts can be used to produce psychotropic effects when are combined with psychotropic drugs based on amino groups. Since the occurrence and the levels of the HAlks in natural sources are subject to significant variability, more widespread use is not clinical but recreational or ritual, for example B. caapi is a known part of the Ayahuasca ritual mixture. The lack of simple methods to control the variable levels of these compounds in natural sources restricts the possibilities to dose in strict quantities and, as a consequence, limits its use with pharmacological or clinical purposes. In this work, we present a fast, simple, and robust method of quantifying simultaneously the six HAlks more frequently found in plants, i.e., harmine, harmaline, harmol, harmalol, harmane, and norharmane, by capillary electrophoresis instruments equipped with the more common detector UV. The method is applied to analyze these HAlks in P. Harmala seeds infusion which is a frequent intake form for these HAlks. The method is validated in three different instruments in order to evaluate the transferability and to compare the performances between them. In this case, harmaline, harmine, and harmol were found in the infusion samples. Copyright &copy; 2016 John Wiley &amp; Sons, Ltd.","palabras_clave":"CAPILLARY ELECTROPHORESIS|B-CARBOLINES|OPTIMIZATION|HARMALA ALKALOIDS|PEGAUM HARMALA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4126,"idioma_id":4,"titulo":"Estimating daily net radiation in the FAO Penman - Monteith method","resumen":"In this work, we evaluate the procedures of the Manual No. 56 of the FAO (United Nations Food and Agriculture Organization) for predicting daily net radiationusing measures collected in Tandil (Argentina) between March 2007 and June 2010. In addition, a new methodology is proposed for estimating daily net radiationover the reference crop considered in the FAO Penman?Monteith method. The calculated and observed values of daily net radiation are compared. Estimationerrors are reduced from ±22 to ±12 W m&#8722;2 considering the new model. From spring?summer data, estimation errors of less than ±10 % were observed for the newphysical model, which represents an error of just ±0.4 mm d&#8722;1 for computing reference evapotranspiration.The new model presented here is not restricted to a climate regime and is mainly appropriate for application in the FAO Penman?Monteith method to determine the reference crop evapotranspiration.","palabras_clave":"Sin palabras claves"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4138,"idioma_id":5,"titulo":"REFLEXIONES SOBRE EL RELEVAMIENTO Y ANÁLISIS COMPARATIVO DE PATOLOGÍAS OSTEOARTICULARES EN RESTOS ESQUELETALES HUMANOS","resumen":"Desde los inicios de la bioarqueología, los estudios de las alteraciones osteoarticulares utilizandefiniciones, protocolos de relevamiento y propuestas de análisis de los datos muy variados, lo cualgeneralmente imposibilita su adecuada comparación. En este trabajo se discuten algunos problemasderivados de esa diversidad de perspectivas, con el objetivo de plantear la necesidad de formularcriterios consensuados de registro y análisis que permitan generar datos comparables. Se reflexionasobre aspectos relativos al proceso de relevamiento de los indicadores osteoarticulares y deprocesamiento de la información, al mismo tiempo que se plantean opciones terminológicas yprocedimentales que contribuyan a generar un marco general para el desarrollo de estudiosmultimuestrales.","palabras_clave":"PALEOPATOLOGIA|BIOARQUEOLOGIA|REGISTRO CONSENSUADO|LESIONES OSTEOARTICULARES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4156,"idioma_id":4,"titulo":"Argentine Goverment Policies: Impacts on the Beef Sector","resumen":"Beef is a staple food for Argentine consumers, and although the country has been a major exporter, the highest proportion of beef production is consumed in the domestic market. With rising inflation rates in the last 5&nbsp;years, and given the beef prices? strong weight on the composition of the Consumer Price Index, the Argentine government began taking measures to control it. They initially forced price agreements with members of the marketing and production chain and ended up with a total ban on exports. The results were not as expected and caused serious distortions at different levels of the beef chain. This study aimed to determine whether the impact on some economic and production variables would have been different without such intervention. A VAR model was estimated in order to compare the observed behavior with intervention measures and estimated predictions with a theoretically free market.","palabras_clave":"Argentine Beef Exports|VAR Model|Policy Impacts"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4172,"idioma_id":4,"titulo":"Interaction Models and Automated Control under Partial Observable Environments","resumen":"The problem of automatically constructing a software component such that when executed in a given environment satisfies a goal, is recurrent in software engineering. Controller synthesis is a field which fits into this vision. In this paper we study controller synthesis for partially observable LTS models. We exploit the link between partially observable control and non-determinism and show that, unlike fully observable LTS or Kripke structure control problems, in this setting the existence of a solution depends on the interaction model between the controller-to-be and its environment. We identify two interaction models, namely Interface Automata and Weak Interface Automata, define appropriate control problems and describe synthesis algorithms for each of them.","palabras_clave":"Síntesis de Controladores|Ingeniería de Software|Verificación"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4226,"idioma_id":4,"titulo":"Design and in vitro characterization of Ivermectin nanocrystals liquid formulation based on a top-down approach","resumen":"The aim of this study was to develop ivermectin (IVM) nanosuspensions (NSs) to improve the dissolution rate of this poorly water-soluble drug. Different NSs combining different stabilizers, i.e. poloxamer 188 (P188), polysorbate 80 (T80), polyvinylpyrrolidone (PVP), and sodium lauryl sulfate (SLS), were prepared by high-pressure homogenization. The stabilizers were selected based on the saturation solubility and IVM stability within 72 h. The screening of formulations was performed by considering the drug content within the nanosize range. The best formulation (IVM:T80:PVP 1:0.5:0.5 wt%) was characterized in terms of the particle size distribution, morphology, crystallinity, drug content, and in vitro dissolution profile. This NS was also evaluated from a stability point of view, by conditioning samples at a constant temperature and relative humidity for six months. The fresh and conditioned best NSs Z-sizes were 174.6 and 215.7 nm, respectively; while both NSs showed low polydispersity indexes. The faster dissolution rate for the IVM NS was attributed to the presence of nanoparticles and changes to the crystal structure (i.e. amorphization) that further improved solubility. The best NS had a 4-fold faster initial dissolution rate than raw IVM, and is thus a promising formulation for the treatment of human and animal parasitic diseases.","palabras_clave":"DISSOLUTION|HIGH PRESSURE HOMOGENIZATION|IVERMECTIN|NANOPARTICLES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4270,"idioma_id":4,"titulo":"Oxidative stress, HDL functionality and effects of intravenous iron administration in women with iron deficiency anemia","resumen":"BACKGROUND AND AIMS:Iron deficiency anemia (IDA) affects around 20-30% of adults worldwide. An association between IDA and cardiovascular disease (CVD) has been reported. Oxidative stress, inflammation and low concentration of high-density lipoproteins (HDL) were implicated on endothelial dysfunction and CVD in IDA. We studied the effects of iron deficiency and of an intravenous iron administration on oxidative stress and HDL characteristics in IDA women.METHODS:Two studies in IDA women are presented: a case-control study, including 18 patients and 18 age-matched healthy women, and a follow-up study 72hr after the administration of intravenous iron (n = 16). Lipids, malondialdehyde, cholesteryl ester transfer protein (CETP), paraoxonase-1 (PON-1) and HDL chemical composition and functionality (cholesterol efflux and antioxidative activity) were measured. Cell cholesterol efflux from iron-deficient macrophages to a reference HDL was also evaluated.RESULTS:IDA patients showed higher triglycerides and CETP activity and lower HDL-C than controls (all p < 0.001). HDL particles from IDA patients showed higher triglyceride content (+30%,p < 0.05) and lower antioxidative capacity (-23%,p < 0.05). Although HDL-mediated cholesterol efflux was similar between the patients and controls, iron deficiency provoked a significant reduction in macrophage cholesterol efflux (-25%,p < 0.05). Arylesterase activity of PON-1 was significantly lower in IDA patients than controls (-16%,p < 0.05). The intravenous administration of iron was associated with a decrease in malondialdehyde levels and an increase in arylesterase activity of PON-1 (-22% and +18%, respectively, p < 0.05).CONCLUSION:IDA is associated with oxidative stress and functionally deficient HDL particles. It remains to be determined if such alterations suffice to impair endothelial function in IDA.","palabras_clave":"IRON DEFICIENCY |PARAOXONASE|ANEMIA|HDL|OXIDATIVE STRES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4297,"idioma_id":4,"titulo":"Compartmentalization of Hepatitis C Virus Variants in Patients with Hepatocellular  Carcinoma","resumen":"Chronic Hepatitis C Virus (HCV) infection is a major risk for hepatocellular carcinoma (HCC) development. HCV Core protein has been associated with the modulation of potentially oncogenic cellular processes and E2 protein has been useful in evolutive studies to analyze the diversity of HCV. Thus, the aim of this study was to evaluate HCV compartmentalization in tumoral, nontumoral liver tissue and serum and to identify viral mutations potentially involved in carcinogenesis. Samples were obtained from four patients with HCC who underwent liver transplantation. Core and E2 were amplified, cloned and sequenced. Phylogenies and BaTS Test were performed to analyzeviral compartmentalization and a signature sequence analysis was conducted by VESPA. The likelihood and Bayesian phylogenies showed a wide degree of compartmentalization in the different patients, ranging from total clustering to a more scattered pattern with small groups. Nevertheless, the association test showed Compartmentalization for the three compartments and both viral regions tested in all the patients. Signature amino acid pattern supported the compartmentalization in three of the cases for E2 protein and in two of them for Core. Changes observed in Core included polymorphism R70Q\/H previously associated with HCC. In conclusion, evidence of HCV compartmentalization in the liver of HCC patients was provided and further biological characterization of these variants may contribute to the understanding of carcinogenesis mediated by HCV infection.","palabras_clave":"HCV|HEPATOCELLULAR CARCINOMA|QUASISPECIES|COMPARTIMENTALIZATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4307,"idioma_id":4,"titulo":"Dissemination of Visceral Leishmaniasis to Western Argentina, when will imported canine vector borne zoonotic diseases start being local?","resumen":"Visceral leishmaniasis (VL), caused by Leishmania infantum (syn. chagasi) is expanding at an alarming rate in Argentina. Since the first diagnosis in Argentina in May 20061 in the Northeastern province of Misiones, with previous reports across the border in Paraguay,  now there are thousands of cases in dogs and over one hundred of human cases (many fatal) have been diagnosed in throughout most of the north and northeastern  provinces of Argentina (Figure 1)2,3. The disease has travelled over one thousand kilometers, and so has its vectors and main reservoir, the domestic dog. The vectors described for VL in Argentina, Lutzomia longipalpis and Mygonemia migonei, have also been detected in the provinces of Catamarca, Santa Fé and Córdoba, where no human or canine cases have been described yet. Be it expensive dogs destined for breeding or the dogs of migrant harvest workers, they can wander freely through the country and so can their parasites. Albeit the intentions of rooting out the paradigm of ?exotic disease? it is still firmly attached in the minds and hearts of health professionals, both from the human and veterinary fields. Arid Cuyo region by the Andes in Western Argentina is far from being the site where one expects the introduction of diseases transmitted by mosquitoes, yet, in Lavalle desert of Mendoza province, with barely 100 mm of rainfall per year, a prevalence of 52 % for Dirofilaria immitis has been detected in dogs. An autochthonous case of human dirofilariasis has been reported in the neighboring (also very arid) province of San Juan. Yet, a serological survey done in dogs more than a decade ago couldn?t detect any positive cases in the region. In a span of three years, tick transmitted diseases (hepatozoonosis, ehrlichiosis and babesiosis) have been diagnosed for the first time in the region. To present, three canines cases of VL have been reported in the city of Mendoza, one imported from Paraguay, and two other introduced from endemic regions of Argentina, over 1,500 kilometers away. These dogs were purebred animals with educated owners with knowledge of the disease, which promptly contacted a veterinarian when the dogs presented compatible symptoms. In Mendoza, human cases of tegumentary leishmaniasis (TL) are frequently diagnosed yet all of them are introduced from endemic regions, sometimes symptomatic and living in the province for many years before the correct diagnosis was made4.  The question is what is behind this expansion? The tendency is to put the focus on climate change, yet, in the case of dirofilariasis in Mendoza, at least temperature will not account for the expansion5. More assumptions than certainties can be made. Yet, the reality is still the same. Dogs can be Trojan horses, delivering unknown dangers, or they can be the canary in the coal mine, alerting us of imminent peril. The one world one- health approach is currently more a necessity than just a statement. Either that or we shall be mere sitting ducks, waiting for the vectors to catch up with the parasites.","palabras_clave":"VISCERAL LEISHMANIASIS|CANINE|MENDOZA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4343,"idioma_id":5,"titulo":"Validación de un cuestionario de actividad física en niños y adolescentes de Argentina","resumen":"La Encuesta de la Deuda Social Argentina (EDSA) es un instrumento multipropósito que recolecta datos de hogares y personas en ciudades de Argentina. Posee un módulo específico para estimar el cumplimiento de derechos de niños y adolescentes, y aspectos del desarrollo humano. Es aplicada todos los años en una muestra probabilística de 5.700 hogares en grandes aglomeraciones urbanas. Se desarrolló un subapartado de 5 ítems que indaga sobre la frecuencia semanal y el tiempo de realización de actividades físicas de intensidades moderada y vigorosa (AFMV), y se construye un índice para estimar si se cumple o no con la recomendación de al menos 60 minutos de AFMV. El objetivo fue comprobar la validez de criterio de estas preguntas, en una muestra de niños y adolescentes entre 7 y 17 años (n&#8201;=&#8201;151; 70 varones y 81 mujeres) de nivel socioeconómico medio-alto y medio-bajo. Las mediciones del criterio se obtuvieron por acelerometría. Los participantes llevaron un acelerómetro CSA 7164 durante 7 días y el adulto referente respondió a la EDSA de modo completo (incluyendo los 5 ítems de actividad física). La AFMV por acelerometría correlacionó con el tiempo de actividad física diario promedio (TAFD) (r&#8201;=&#8201;0,22; p&#8201;<&#8201;0,01). Si bien la correlación es baja, se revelaría la validez del criterio para estimar AFMV.","palabras_clave":"INFANCIAS|Adolescencia|Actividad Física"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4370,"idioma_id":5,"titulo":"PATRIMONIOS EN EL PAISAJE LA CARACTERIZACIÓN HISTÓRICA DEL TERRITORIO Y EL PATRIMONIO ARQUEOLÓGICO DEL CENTRO DE LA PROVINCIA DE BUENOS AIRES","resumen":"En los últimos años, el grupo de investigación interdisciplinario PATRIMONIA ha desarrollado una base de datos para sistematizar las principales características del Patrimonio Arqueológico de los municipios de Tandil, Olavarría y Azul, ubicados en el centro geográfico de la provincia de Buenos Aires, incluyendo un estudio preliminar de su significación social. La finalidad de esto fue crear un sistema de información geográfica (SIG) que constituyera un insumo para la gestión de los recursos culturales en el área. El objetivo de este trabajo es presentar el análisis espacial e histórico del territorio y las características particulares del Patrimonio Arqueológico contenido en él, para luego discutir cuestiones relacionadas con su vulnerabilidad y posibles estrategias que contribuyan a su salvaguarda.","palabras_clave":"PATRIMONIO ARQUEOLOGICO|PAISAJE|VULNERABILIDAD|SALVAGUARDA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4417,"idioma_id":4,"titulo":"Non-myogenic tumors display altered expression of dystrophin (DMD) and a high frequency of genetic alterations","resumen":"DMD gene mutations have been associated with the development of Dystrophinopathies. Interestingly, it has been recently reported that DMD is involved in the development and progression of myogenic tumors, assigning DMD a tumor suppressor activity in these types of cancer. However, there are only few reports that analyze DMD in non-myogenic tumors. Our study was designed to examine DMD expression and genetic alterations in non-myogenic tumors using public repositories. We also evaluated the overall survival of patients with and without DMD mutations. We studied 59 gene expression microarrays (GEO database) and RNAseq (cBioPortal) datasets that included 9817 human samples. We found reduced DMD expression in 15\/27 (56%) pairwise comparisons performed (Fold-Change (FC) &#8804; 0.70; p-value range = 0.04-1.5x10-20). The analysis of RNAseq studies revealed a median frequency of DMD genetic alterations of 3.4%, higher or similar to other well-known tumor suppressor genes. In addition, we observed significant poorer overall survival for patients with DMD mutations. The analyses of paired tumor\/normal tissues showed that the majority of tumor specimens had lower DMD expression compared to their normal adjacent counterpart. Interestingly, statistical significant over-expression of DMD was found in 6\/27 studies (FC &#8805; 1.4; p-value range = 0.03-3.4x10-15). These results support that DMD expression and genetic alterations are frequent and relevant in non-myogenic tumors. The study and validation of DMD as a new player in tumor development and as a new prognostic factor for tumor progression and survival are warranted.","palabras_clave":"TUMORES|DISTROFINA|MICROARRAYS|RNASEQ"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4424,"idioma_id":4,"titulo":"In vitro alterations of erythrocyte aggregation by action of Trichinella spiralis newborn larvae","resumen":"Possible changes in the erythrocyte membrane, by in vitro interaction with newborn larvae of T. spiralis (NL), were evaluated analyzing the alterations in erythrocyte aggregation by digital image analysis and laser transmission in a new optical chip aggregometer. NL were obtained from CBi mice infected with T. spiralis. RBCs samples from healthy donors where in vitro exposed to NL (concentration (3000 ± 500) larvae\/mL) to assess its effect on RBC aggregation. Individual cell Coefficient (CCA) and aggregation parameter (S) were calculated by digitally processing RBC aggregate images, indicating the amount and size of the erythrocyte aggregates present. Also, size distribution of aggregate was analyzed. Kinetic aggregation parameters (Amp750 and t1\/2) were calculated with a new optical chip aggregometer. Results show significant alterations in erythrocyte aggregability due the in vitro action of T. spiralis larvae increasing incubation time. These results are possibly related to the loss of surface sialic acid as it is captured by NL. Obtained results suggest that NL could produce hemorheological alterations in the host, which could be related to thrombosis and anemia reported in some patients with trichinosis.","palabras_clave":"TRICHINOSIS|ERYTHROCYTE AGGREGATION|OPTICAL CHIP|DIGITAL IMAGE ANALYSIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4426,"idioma_id":5,"titulo":"Caracterización fisicoquímica, óptica y reológica de soluciones extractivas de Phyllanthus sellowianus y Bauhinia forficata","resumen":"Las especies Phyllanthus sellowianus (Ps) o Sarandí Blanco y Bauhinia forficata (Bf) o Pezuña de Vaca, se encuentran naturalmente y se utilizan tradicionalmente en nuestro país para el tratamiento de la Diabetes. En este trabajo se prepararon distintas soluciones extractivas acuosas con el leño y las hojas de las especies mencionadas y se midieron los parámetros fisicoquímicos, ópticos y reológicos de las mismas. Los resultados obtenidos permiten una caracterización de estos extractos demostrando la presencia de distintos componentes químicos, como compuestos fenólicos y saponinas triterpénicas, variando su concentración según el método de extracción empleado. Estos resultados ayudarán a estudios futuros para una mejor comprensión de los mecanismos de acción por los cuales los extractos de estas especies o sus componentes fitoquímicos pueden ser utilizados para el tratamiento de la Diabetes en fitomedicina.","palabras_clave":"Diabetes|Soluciones Extractivas|Fisicoquímico|Reológico"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4498,"idioma_id":4,"titulo":"CDOM and the underwater light climate in two shallow North Patagonian lakes: evaluating the effects on nano and microphytoplankton community structure","resumen":"We performed an annual synchronous sampling in two oligotrophic shallow lakes to assess the influence of chromophoric dissolved organic matter (CDOM) on the underwater light climate, and its potential effects on the nano and microphytoplankton community structure. Lake Escondido showed higher CDOM concentration and light attenuation with a spectral composition of underwater light shifted towards green?yellow light, while Lake Morenito presented clearer waters and a dominance of green light. Temporal dynamics of CDOM absorption at 440 nm were consistently explained by differences in cumulative pre- cipitation. Mixotrophic cryptophytes and chrysophytes dominated the phytoplankton of both lakes, although the prevalence of each algal group was different between lakes. The dominance of these groups was largely explained by differences in spectral composition of underwater light, estimated as the ratio between Kd(RED) and Kd(GREEN) [Kd(R)\/Kd(G) ratio]. Cryptophytes prevailed in Lake Morenito and their biomass showed a positive strong relationship with Kd(R)\/Kd(G) ratio. Chrysophyte biomass was comparatively more important in Lake Escondido showing an opposite relationship with the Kd(R)\/ Kd(G) ratio. These results underscore that higher relative green light availability allowed the dominance of crypto- phytes, while changes in light spectral composition driven by CDOM allowed coexistence. We suggest that nano and microphytoplankton community structure in these lakes could be driven by changes in spectral composition of underwater light shaped by differences in CDOM, ulti- mately determined by precipitation\/hydrological patterns.","palabras_clave":"UNDERWATER LIGHT|NANOPHYTOPLANKTON|MICROPHYTOPLANKTON|COMMUNITY STRUCTURE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4524,"idioma_id":4,"titulo":"Memory consolidation and expression of object recognition are susceptible to retroactive interference","resumen":"With the aim of analyzing if object recognition long-term memory (OR-LTM) formation is susceptible to retroactive interference (RI), we submitted rats to sequential sample sessions using the same arena but changing the identity of a pair of objects placed in it. Separate groups of animals were tested in the arena in order to evaluate the LTM for these objects. Our results suggest that OR-LTM formation was retroactively interfered within a critical time window by the exploration of a new, but not familiar, object. This RI acted on the consolidation of the object explored in the first sample session because its OR-STM measured 3 h after training was not affected, whereas the OR-LTM measured at 24 h was impaired. This sample session also impaired the expression of OR memory when it took place before the test. Moreover, local inactivation of the dorsal Hippocampus (Hp) or the medial Prefrontal Cortex (mPFC) previous to the exploration of the second pair of objects impaired their consolidation restoring the LTM for the objects explored in the first session. This data suggests that both brain regions are involved in the processing of OR-memory and also that if those regions are engaged in another process before finishing the first consolidation process its LTM will be impaired by RI.","palabras_clave":"OBJECT RECOGNITION|LONG-TERM MEMORY|RETROACTIVE INTERFERENCE|RAT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4674,"idioma_id":4,"titulo":"Differential control and function of Arabidopsis ProDH1 and ProDH2 genes upon infection with biotrophic and necrotrophic pathogens","resumen":"Arabidopsis contains two proline dehydrogenase (ProDH) genes, ProDH1 and ProDH2, encoding for homologous and functional isoenzymes. Although ProDH1 has been studied extensively, especially under abiotic stress, ProDH2 has only started to be analysed in recent years. These genes display distinctive expression patterns and show weak transcriptional co-regulation, but are both activated in pathogen-infected tissues. We have demonstrated previously that Arabidopsis plants with silenced ProDH1\/2 expression fail to trigger defences against the hemibiotrophic bacterial pathogen Pseudomonas syringae pv. tomato AvrRpm1 (Pst-AvrRpm1), and that ProDH1 and ProDH2 are differentially regulated by salicylic acid (SA). In the current work, we used prodh1 and prodh2 single-mutant plants to assess the particular contribution of each gene to resistance against Pst-AvrRpm1 and the necrotrophic fungal pathogen Botrytis cinerea. In addition, we studied the sensitivity of ProDH1 and ProDH2 to the jasmonic acid (JA) defence pathway. We found that ProDH1 and ProDH2 are both necessary to achieve maximum resistance against Pst-AvrRpm1 and B. cinerea. However, ProDH2 has a major effect on early restriction of B. cinerea growth. Interestingly, ProDH1 is up-regulated by SA and JA, whereas ProDH2 is only activated by JA, and both genes display transcriptional inter-regulation at basal and infection conditions. These studies provide the first evidence of the contribution of ProDH2 to disease resistance, and describe the differential regulation and non-redundant but complementary function of both enzyme isoforms in infected tissues, providing support for a fundamental role of ProDH in the control of biotrophic and necrotrophic pathogens.","palabras_clave":"proline dehydrogenase|biotrophic and necrotrophic pathogens|arabidopsis"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4708,"idioma_id":4,"titulo":"Impact of the Induced Organic anion transporters 1 (Oat1) Renal Expression by Furosemide on the Pharmacokinetics of Organic Anions","resumen":"AIM:Furosemide is a loop diuretic. Different authors demonstrated that continuous administration of furosemide modulates the expression of organic anion transporters. This study was undertaken to simultaneously evaluate the effects of furosemide pretreatment on organic anion transporter 1 (Oat1) and multidrug resistance protein 2 (Mrp2) renal expressions, on p-aminohippurate (PAH) pharmacokinetics and on renal and urinary PAH levels in rats.METHODS:Male Wistar rats were treated with furosemide (6&#8201;mg\/100&#8201;g b.w.\/day, s.c, 4&#8201;days) (Treated group) or saline (Control group). On the 5th day, PAH was administered as a bolus infusion in the femoral vein and plasma samples were obtained from femoral artery at different time points. PAH levels in renal tissue and urine were also assessed. Renal Oat1 and Mrp2 expressions were evaluated by Western blotting.RESULTS:Furosemide pretreatment increased both the expression of Oat1 and Mrp2. PAH plasma concentrations decreased following a biexponential function. Furosemide-treated group showed higher PAH plasma levels, a lower systemic clearance and elimination rate constant from the peripheral compartment, indicating that PAH renal elimination was decreased. PAH levels in renal tissue were significantly elevated and in urine appeared to be significantly lower as compared with control animals.CONCLUSIONS:Furosemide pretreatment caused a significant decrease of PAH renal elimination, despite Oat1 and Mrp2 augmented renal expression. The goal of the present study is the addition of important information in the wide gap of knowledge that exists about drug-drug interactions. Due to furosemide worldwide use, the data obtained are interesting and useful in terms of translation to clinical practice.","palabras_clave":"FUROSEMIDE|ORGANIC ANIONS|Oat1|PHARMACOKINETICS|Mrp2"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4709,"idioma_id":4,"titulo":"Phosphoinositides: Two-Path Signaling in Neuronal Response to Oligomeric Amyloid &#946; Peptide","resumen":"We have previously demonstrated that oligomericamyloid &#946; peptide (oA&#946;) together with iron overload generatessynaptic injury and activation of several signaling cascades.In this work, we characterized hippocampal neuronalresponse to oA&#946;. HT22 neurons exposed to 500 nM oA&#946;showed neither increased lipid peroxidation nor altered mitochondrialfunction. In addition, biophysical studies showedthat oA&#946; did not perturb the lipid order of the membrane.Interestingly, although no neuronal damage could be demonstrated,oA&#946; was found to trigger bifurcatedphosphoinositide-dependent signaling in the neuron, onone hand, the phosphorylation of insulin receptor, thephosphatidylinositol 3-kinase (PI3K)-dependent activationof Akt, its translocation to the nucleus and the concomitantphosphorylation, inactivation, and nuclear exclusionof the transcription factor Forkhead Box O3a (FoxO3a), andon the other, phosphoinositide-phospholipase C (PI-PLC)-dependentextracellular signal-regulated kinase 1\/2 (ERK1\/2) activation.Pharmacological manipulation of the signaling cascadeswas used in order to better characterize the role ofoA&#946;-activated signals, and mitochondrial function was determinedas a measure of neuronal viability. The inhibition ofPI3K, PI-PLC, and general phosphoinositide metabolism impairedneuronal mitochondrial function. Furthermore, increasedoA&#946;-induced cell death was observed in the presenceof phosphoinositide metabolism inhibition. Our resultsallow us to conclude that oA&#946; triggers the activation ofphosphoinositide-dependent signaling, which results in thesubsequent activation of neuroprotective mechanisms thatcould be involved in the determination of neuronal fate.","palabras_clave":"Amyloid &#946; peptide|Phosphoinositides|PI3K|FoxO|PI-PLC|ERK1\/2"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4715,"idioma_id":4,"titulo":"Xanthomonas citri subsp. citri requires the outer membrane porin OprB for maximal virulence and biofilm formation","resumen":"Xanthomonas citri ssp. citri (Xcc) causes canker disease in citrus, and biofilm formation is critical for the disease cycle. OprB (Outer membrane protein B) has been shown previously to be more abundant in Xcc biofilms compared with the planktonic state. In this work, we showed that the loss of OprB in an oprB mutant abolishes bacterial biofilm formation and adherence to the host, and also compromises virulence and efficient epiphytic survival of the bacteria. Moreover, the oprB mutant is impaired in bacterial stress resistance. OprB belongs to a family of carbohydrate transport proteins, and the uptake of glucose is decreased in the mutant strain, indicating that OprB transports glucose. Loss of OprB leads to increased production of xanthan exopolysaccharide, and the carbohydrate intermediates of xanthan biosynthesis are also elevated in the mutant. The xanthan produced by the mutant has a higher viscosity and, unlike wild-type xanthan, completely lacks pyruvylation. Overall, these results suggest that Xcc reprogrammes its carbon metabolism when it senses a shortage of glucose input. The participation of OprB in the process of biofilm formation and virulence, as well as in metabolic changes to redirect the carbon flux, is discussed. Our results demonstrate the importance of environmental nutrient supply and glucose uptake via OprB for Xcc virulence.","palabras_clave":"OPRB|XANTHOMONAS CITRI SUBSP CITRI|BIOFILM|CITRUS CANKER"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4761,"idioma_id":4,"titulo":"Phenological Changes of Blooming Diatoms Promoted by Compound Bottom-Up and Top-Down Controls","resumen":"Understanding phytoplankton species-specific responses to multiple biotic and abiotic stressors is fundamental to assess phenological and structural shifts at the community level. Here, we present the case of Thalassiosira curviseriata, a winter-blooming diatom in the Bahía Blanca Estuary, Argentina, which displayed a noticeable decrease in the past decade along with conspicuous changes in phenology. We compiled interannual field data to assess compound effects of environmental variations and grazing by the invasive copepod Eurytemora americana. The two species displayed opposite trends over the period examined. The diatom decreased toward the last years, mainly during the winters, and remained relatively constant over the other seasons, while the copepod increased toward the last years, with an occurrence restricted to winter and early spring. A quantitative assessment by structural equation modeling unveiled that the observed long-term trend of T. curviseriata resulted from the synergistic effects of environmental changes driven by water temperature, salinity, and grazing. These results suggest that the shift in the abundance distribution of T. curviseriata toward higher annual ranges of temperature and salinity?as displayed by habitat association curves?constitutes a functional response to avoid seasonal overlapping with its predator in late winters. The observed changes in the timing and abundance of the blooming species resulted in conspicuous shifts in primary production pulses. Our results provide insights on mechanistic processes shaping the phenology and structure of phytoplankton blooms.","palabras_clave":"plankton|grazing|selectivity|phenology|structural equation modeling|estuaries"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4764,"idioma_id":4,"titulo":"Lov\\'{a}sz-Schrijver SDP-operator,near-perfect graphs and near-bipartite graphs","resumen":"We study the Lov´asz-Schrijver lift-and-project operator (LS+) based on the cone ofsymmetric, positive semidefinite matrices, applied to the fractional stable set polytope of graphs.The problem of obtaining a combinatorial characterization of graphs for which the LS+-operatorgenerates the stable set polytope in one step has been open since 1990. We call these graphsLS+-perfect. In the current contribution, we pursue a full combinatorial characterization of LS+-perfect graphs and make progress towards such a characterization by establishing a new, closerelationship among LS+-perfect graphs, near-bipartite graphs and a newly introduced conceptof full-support-perfect graphs.","palabras_clave":"Stable set problem   |Lift-and-project methods|Semidefinite programming |Integer programming"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4782,"idioma_id":4,"titulo":"Antagonistic activity of Bacillus sp. strain isolated in Córdoba, Argentina against Macrophomina phaseolina (Tassi) Goid","resumen":"The antifungal activity of Bacillus spp.strains has been already reported against a different number of phytopathogenicfungi3. Some species belonging to thisgenus (i.e. B. subtilis, B. pumilus and B. licheniformis) are considered GRAS (generallyregarding as safe) microorganisms and exhibit potential to enhance plant growth by the production of an amplenumber of beneficial substances1,portraying these species as an environmentally friendly alternative tochemical fungicides. Macrophomina phaseolina (Tassi) Goid is a wide range soil-bornephytopathogenic fungus causing charcoal rot to several significant plant crops in Argentina (i.e. soybean, common bean,peanuts and corn)5,6 and is also capableto affect more than five hundred plant species worldwide4. Its ability to infect these hostplants is commonly correlated to the production of viable sclerotia, anon-sporic resistance structure constituted by a mass of densely packed hyphae, in the field5. In this work, we report theisolation of a Bacillus sp. strain 11.1 obtained from soil samples from Córdoba Province,Argentina2exhibiting a strongantagonistic activity against M. phaseolina. In order to analyse thepotential antagonistic effect of strain 11.1, both microorganisms were grown on dual culture platescontained potato dextrose agar (PDA) and tryptone soya agar (TSA) (1:1 v\/v) and incubated for 48-72hours at 28ºC (Figure 1). An important and irreversible inhibition of the fungal growth was showed (Figure1A). In addition, the fungal mycelium located at the edge of the inhibited region was analysed bymicroscopic examination. The most evident antagonistic effect over the fungus was depicted by the lack ofblack pigmentation and the reduced size of formed sclerotiain comparison with the control (Figure 1B and C).","palabras_clave":"Biocontrol|Macrophomina phaseolina|sclerotia|microscopic examination"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4794,"idioma_id":4,"titulo":"Determination of Volatile Organic Compounds in Andean Tomato Landraces by Headspace Solid Phase Microextraction-Gas Chromatography-Mass Spectrometry","resumen":"Traditional tomatoes (Solanum lycopersicum L.) have been mainly selected for their fruit quality and maintained by local farmers in Andean areas of Cuyo and Northwestern Argentina. Volatile organic compounds (VOCs) in mature fruits of Andean tomato landraces were evaluated for the first time using headspace solid phase microextraction (HS\/SPME) and gas chromatography\/mass spectrometry (GC-MS) and combined with classical multivariate analysis. The data sets composed of 101 volatile metabolites were identi&#64257;ed in 4 accessions of Andean landraces, one commercial variety and one wild tomato accession (Solanum pimpinellifolium L.). The metabolic profile showed typical VOCs of tomato and 21 new compounds never informed in S. lycopersicum. Andean traditional tomatoes have been shown to be metabolically different from wild species. In addition, some varieties of Andean tomatoes have a different profile of VOCs and are richer than the commercial variety. A different and original metabolic volatile composition found in fruits of Andean tomato landraces of Argentina, in comparison with commercial cultivars, might probably reveals selection based on quality attributes made by local farmers.","palabras_clave":"tomato|fruit|SPME |volatile metabolites|multivariate analysis"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4795,"idioma_id":4,"titulo":"Agronomic performance and fruit nutritional quality of an Andean tomato collection","resumen":"Cultivated tomato provides important nutrients to human diet, and its fruits contain . Sseveral fruit compounds, which acting alone or in combination, could be beneficial for human health. A collection of local landracesvarieties hasve been recovered from Andean areas of Argentina, and maintained in the Germplasm Bank of La Consulta INTA, Mendoza. These landraces have been selected by local farmers mainly for their environmental adaptation and  fruit quality traits. Our goal was to establish associations among agronomic properties,,  commercial andfruit nutritional qualities and  commercial characteristics of a collection of this Andean tomatoes collection. For this purpose 32 tomato accessions were used, and the wild species type accession LA1589 Solanum pimpinellifolium as contrasting control were evaluatedincluded. Tomato plants were grown at the Experimental Station La Consulta INTA, using a randomized block designs. Analyses were performed on mature red fruit. For the morpho-agronomic characterization 19 traits were recorded. Metabolite fruit contents were evaluated by HPLC, MNR and GC-MS. All data were integrated using multiple variable analyses. Fruit size was inversely correlated with the content of free amino acids, suggesting a dilution effect. Fruit shape and size partially correlated with sugar and organic acids content. Shape and pericarp thickness were associated with organic acids, free amino acids, and aromatic compounds, as well as with pH and juice acidity; although nonet correlation was found with soluble solids, dry matter or pericarp firmness. Color intensity of fruit showed a clear association with the increase of few metabolites and the decrease of several aromatic compounds and alcohols. Different independent selection events would have generated different genetic constitutions, confirming that traditional agricultural habitats are fundamental reservoirs of genetic diversity. These data suggest that improvements in the nutritional value of tomato would complement the agronomic properties, and the collection of Andean tomatoes possess an interesting metabolite variability available for breeding purposes.allowing selecting cultivars that better adapt to different purposes.","palabras_clave":"Solanum lycopersicum|landraces|germplasm characterization|metabolite profile|fruit quality"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4796,"idioma_id":4,"titulo":"Nutritional quality of oranges tomatoes for fresh consumption and processing products","resumen":"In Argentina, traditionally commercial tomatoes for fresh consumption as well for processed products have red fruits. Although, other fruit colors (yellow, purple) are present in the ?cherry? types, orange tomatoes for direct consumption or for the industry are not found in the market. Our objective was diversify tomato market generating cultivars of different color and non-traditional fruit characteristics. Field comparative trials during several cycles at the Institute of Horticulture (FCA-UNCuyo, Mendoza) allowed the selection of two cultivars with good agronomic performance, productivity and fruit quality:  cultivar 1 with determinate growth, with 3-5 fruits per cluster, fruit pear shape with a mammillate tip, orange, jointless;  and cultivar 2 with indeterminate growth, with 3-5 fruits per cluster, oval, deep orange, jointless or with not functional pedicel articulation. Fruits of the two varieties have good internal and external color, adequate pericarp thickness, homogeneous maturation, and fruits adapted to manual and mechanical concentrated harvest. Mature fresh fruits were characterized by physico-chemical composition, total polyphenols, lycopene and &#61538;-carotene content, and antioxidant activity, showing an interesting nutritional composition and different antioxidant properties. Using mature fruits, a marmalade was produced at the Pilot Processing Industry (FCA-UNCuyo, Mendoza), and its nutritional composition as well as the phytochemical contribution (polyphenols, lycopene and y &#61538;-carotene) and antioxidant activity were determined. Finally, acceptability of the new product was assessed by a written questionnaire about sensorial qualities (color, flavor, texture, etc.) that was completed by 131 consumers.  The marmalade had a high acceptance and constitute and interesting product with excellent nutritional value that also could cover part of the required antioxidant compounds in human diets.  At present, the orange marmalade is commercialized locally by the Agronomy Faculty with a significant acceptance by consumers. Orange tomato varieties have excellent nutritional properties and sensorial characteristics for direct consumption and also for industrial processed products.","palabras_clave":"orange tomatoes|antioxidants|processing products|sensorial qualities|marmalade"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4819,"idioma_id":4,"titulo":"PHYSICAL TREATMENTS AND PROPOLIS EXTRACT TO  ENHANCE QUALITY ATTRIBUTES OF FRESH-CUT MIXED  VEGETABLES","resumen":"The impact of individual and combined application of propolis extract (PE) plus ultrasound (ULT) or thermal treatment (TT) on the microbiological, nutritional,physicochemical and sensory quality of fresh-cut mixed vegetables for soup (celery,leek and butternut squash) stored at 5C was studied. The use of PE slightly reduced microbial growth, inhibited the activity of browning related enzymes and improved quality attributes during refrigerated storage. Moreover, PE was effective to reduce ascorbic acid losses in the product maintaining its nutritional quality. TT greatly lowered the initial microbial load (1.7?2.2 log units) and also reduced microbial growth on mixed vegetables extending its microbiological shelf-life to 5 days. Furthermore,TT inactivated browning enzymes improving visual quality; however, ascorbic acid degradation adversely affected nutritional quality. Meanwhile, ULT caused a significant microbial inactivation, reduced browning enzyme activity and also the inhibitory effect on polyphenoloxidase enzyme was enhanced by combining ULT with PE.","palabras_clave":"NATURAL EXTRACTS|PROPOLIS|FISICAL TREATMENTS|VEGETABLES READY TO USE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4831,"idioma_id":4,"titulo":"Evaluation of mutagenicity associated with Escherichia coli inactivation in UV-treated orange juice","resumen":"UV radiation is an alternative technology for the elimination of pathogenic micro-organisms in liquid food. The objectives of this work were to investigate mutagenesis using the Ames test in : (1)fresh squeezed orange juice submitted to UV radiation doses required to achieve 5 and 10 log10 reductions of different strains of Escherichia coli serotype O157:H7 at two temperatures, and (2)commercial pasteurized orange juice submitted to thermal treatment.Two histidine-auxotrophic strains, Salmonella Typhimurium TA98 and TA97a, were used in the Ames test with and without metabolic activation.In commercial pasteurized orange juices, mutagenesis was not observed with S. Typhimurium TA98 strain with and without metabolic activation, but high mutagenic effect was observed using TA97a with metabolic activation.UV radiation did not affect the stability of ascorbic acid in aqueous solution. However, degradation of ascorbic acid was observed when UV treatment was performed on squeezed orange juice, following first order kinetics.UV treatment required to achieve 5 log10 reductions (1.5 J\/cm2) did not show a mutagenic effect with and without metabolic activation using the tested strains, but a higher UV radiation dose necessary to produce 10 log10 reductions (3.0 J\/cm2) showed mutagenicity with metabolic activation.","palabras_clave":"MUTAGENICITY |UV RADIATION |ORANGE JUICE |AMES TEST  |ASCORBIC ACID"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4843,"idioma_id":4,"titulo":"Inhibition of MHC-I by Brucella abortus is an early event during infection and involves EGFR pathway","resumen":"Brucella abortus is able to persist inside the host despite the development of potent CD8 + T-cell responses. We have recently reported the ability of B. abortus to inhibit the interferon-&gamma;-induced major histocompatibility complex (MHC)-I cell surface expression on human monocytes. This phenomenon was due to the B. abortus-mediated retention of MHC-I molecules within the Golgi apparatus and was dependent on bacterial viability. However, the implications of bacterial virulence or replicative capacity and the signaling pathways remained unknown. Here we demonstrated that the B. abortus mutant strains RB51 and virB10 - are able to inhibit MHC-I expression in the same manner as wild-type B. abortus, even though they are unable to persist inside human monocytes for a long period of time. Consistent with this, the phenomenon was triggered early in time and could be observed at 8 h postinfection. At 24 and 48 h, it was even stronger. Regarding the signaling pathway, targeting epidermal growth factor (EGF) receptor (EGFR), ErbB2 (HER2) or inhibition of tumor necrosis factor-&alpha;-converting enzyme, one of the enzymes which generates soluble EGF-like ligands, resulted in partial recovery of MHC-I surface expression. Moreover, recombinant EGF and transforming growth factor-&alpha; as well as the combination of both were also able to reproduce the B. abortus-induced MHC-I downmodulation. Finally, when infection was performed in the presence of an extracellular signal-regulated kinase 1\/2 (Erk1\/2) inhibitor, MHC-I surface expression was significantly recovered. Overall, these results describe how B. abortus evades CD8 + T-cell responses early during infection and exploits the EGFR-ERK signaling pathway to escape from the immune system and favor chronicity.","palabras_clave":"MHC-I|Brucella abortus|EGFR"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4852,"idioma_id":5,"titulo":"Valoración de l Recurso Suelo mediante la articulación investigación - enseñanza - extensión","resumen":"Articulando enseñanza, con extensión universitaria e investigación, en el presente trabajo se contextualiza y resumen los ejes de trabajo en torno a un proyecto entre la Universidad Nacional de Villa María y la Comunidad Educativa Agrotécnica Rural, que promovió el conocimiento del recurso suelo contribuir a una mejor calidad de vida de la sociedad en un ámbito ambientalmente sustentable. En esta línea, aquí se describen algunos elementos generales del contexto del proyecto, el diagnóstico de partida y las principales actividades desarrolladas con estudiantes de las diferentes áreas de la Universidad Nacional de Villa María en base a las las necesidades y problemáticas ambientales de la comunidad educativa rural en clave de transferencia de experiencias y conocimientos. Finalmente, se resumen algunos elementos y enseñanzas que, a modo de balance, ponen en valor los resultados obtenidos durante el proceso.","palabras_clave":"Rural|Ambiente|Juego"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4884,"idioma_id":4,"titulo":"Thermal Annealing of Polyelectrolyte Multilayers: An Effective Approach for the Enhancement of Cell Adhesion","resumen":"Polyelectrolyte multilayers (PEMs) have many potential applications in tissue engineering and regenerative medicine. However, the softness of biocompatible PEMs results in limited cell adhesion. A novel strategy for the enhancement of cell adhesion on PEMs based on thermal annealing is presented here. The impact of thermal annealing at 37 ºC of poly-l-lysine (PLL) and alginate (Alg) polyelectrolyte multilayers on the adhesion of human lung cancer A549 and myoblast C2C12 cell lines is studied. The properties of the PEMs after annealing are characterized by means of the quartz crystal microbalance with dissipation, atomic force microscopy, atomic force spectroscopy, zeta potential, and contact angle measurements. After annealing, PLL\/Alg PEMs become smoother displaying an increase in stiffness. Furthermore, PEMs become more hydrophobic, with an increase in contact angle from 36° to 90°. Additionally, the surface charge decreases and protein deposition on PEMs significantly diminishes after annealing. Cell adhesion, measured by the projected average cell spreading and focal contact formation, is remarkably improved for the annealed PEMs.","palabras_clave":"POLYELECTROLYTE MULTILAYERS|THERMAL ANNEALING|CELL ADHESION|ANTIFOULING|CONTACT ANGLE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4915,"idioma_id":4,"titulo":"Acetylcholine polarizes dendritic cells toward a Th2- promoting profile","resumen":"BACKGROUND:Maternal antigen-presenting cells attracted to the pregnant uterus interact with trophoblast cells and modulate their functional profile to favour immunosuppressant responses. Non-neuronal cholinergic system is expressed in human cytotrophoblast cells and in immune cells with homeostatic regulatory functions.AIM:The aim of this work was to evaluate whether non-neuronal acetylcholine conditions maternal monocyte and DC migration and activation profiles.METHODS:We used an in vitro model resembling maternal-placental interface represented by the co-culture of human trophoblast cells (Swan-71 cell line) and monocytes or DC.RESULTS:When cytotrophoblast cells were treated with neostigmine (Neo) to concentrate endogenous acetylcholine levels, monocyte migration was increased. In parallel, high levels of IL-10 and decreased levels of TNF-á were observed upon interaction of maternal monocytes with trophoblast cells. This effect was synergized by Neo and was prevented by atropine, a muscarinic acetylcholine receptor antagonist. Similarly, trophoblast cells increased the migration of DC independently of Neo treatment; however, enhanced IL-10 and MCP-1 synthesis in trophoblast-DC co-cultures with no changes in TNF-á and IL-6 was observed. In fact, there were no changes in HLA-DR, CD86 or CD83 expression. Finally, trophoblast cells treated with Neo increased the expression of two antigen-presenting cells attracting chemokines, MCP-1, MIP-1á and RANTES through muscarinic receptors, and it was prevented by atropine.CONCLUSIONS:Our present results support a novel role of acetylcholine synthesized by trophoblast cells to modulate antigen-presenting cell migration and activation favouring an immunosuppressant profile that contributes to immune homeostasis maintenance at the maternal-foetal interface.","palabras_clave":"ACETYLCHOLINE|DENDRITIC CELLS |ALLERGY|TSLP"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4921,"idioma_id":4,"titulo":"Fatty acid composition of high oleic sunflower hybrids in a changing environment","resumen":"High oleic hybrids of sunflower are widely cultivated around the world. The effect of temperature on oleic acid percentage of these hybrids is a concern, since oils with oleic acid percentage above a threshold receive a prime over the regular price. The objective of this work was to identify the main avenues for the genetic improvement of oleic acid percentage of high oleic hybrids of sunflower, both in current and future global warming scenarios. A data set obtained in a trial network allowed to explore the oleic acid percentage response to temperature of high oleic hybrids in the argentine sunflower growing region (between 29 and 38° LS, 46 trials in 15 locations during the period 2005\/06?2012\/2013). A similar data set was used to evaluate the variability in phenology. Mean values and stability across environments of oleic acid percentage differed among the studied high oleic hybrids. Differences in the parameter values of a sigmoid equation evidenced the variability in the response of oleic acid to temperature. Oleic acid percentage was simulated with a model that included this equation coupled to a phenology module, for different sowing dates and locations with contrasting temperature, under current conditions and a global warming scenario. It was possible to identify a low number of temperatures and field environments useful to reproduce the rankings of hybrids obtained with a wide range of temperatures. This information could be used to phenotype for high oleic percentage with a low number of experiments and reduce the efforts to identify better high oleic genotypes. Simulations show that the maximum oleic acid percentage is currently not attained in 50% of the studied hybrids in some sowing dates, even at the warmest locations, while in a future global warming scenario it would not be attained in 30% of the studied hybrids in the colder locations. Sensitivity analysis was performed for parameters of the sigmoid equation and the phenology module determining when the critical period for fatty acid composition occurs. In both in current and future scenarios, phenology parameters showed a null or low effect on oleic acid percentage. Two parameters of the sigmoid equation showed a significant impact, which differed between current and future scenarios. Simulations suggest that the stability of oleic acid percentage could still be a concern in the future. However, selecting for key parameter values for a given scenario could help to obtain better high oleic hybrids of sunflower.","palabras_clave":"GLOBAL WARMING|HIGH OLEIC HYBRIDS|MODELING|STABILITY|TEMPERATURE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4927,"idioma_id":4,"titulo":"The sparkling Universe: a scenario for cosmic void motions","resumen":"We analyse the clustering of cosmic voids using a numerical simulationand the main galaxy sample from the Sloan Digital Sky Survey. We takeinto account the classification of voids into two types that resembledifferent evolutionary modes: those with a rising integrated densityprofile (void-in-void mode or R-type) and voids with shells(void-in-cloud mode or S-type). The results show that voids of the sametype have stronger clustering than the full sample. We use thecorrelation analysis to define void clumps, associations with at leasttwo voids separated by a distance of at most the mean void separation.In order to study the spatial configuration of void clumps, we computethe minimal spanning tree and analyse their multiplicity, maximum lengthand elongation parameter. We further study the dynamics of the smallersphere that enclose all the voids in each clump. Although the globaldensities of void clumps are different according to their member-voidtypes, the bulk motions of these spheres are remarkably lower than thoseof randomly placed spheres with the same radius distribution. Inaddition, the coherence of pairwise void motions does not stronglydepend on whether voids belong to the same clump. Void clumps are usefulto analyse the large-scale flows around voids, since voids embedded inlarge underdense regions are mostly in the void-in-void regime, wherethe expansion of the larger region produces the separation of voids.Similarly, voids around overdense regions form clumps that are incollapse, as reflected in the relative velocities of voids that aremostly approaching.","palabras_clave":"SPARKLING|UNIVERSE|COSMIC|VOID"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4935,"idioma_id":4,"titulo":"Kinetic and Thermodynamic Studies of the Interaction between Activating and Inhibitory Ly49 Natural  Killer Receptors and MHC Class I Molecules","resumen":"Natural killer (NK) cells are lymphocytes of the innate immune system that eliminate virally infected or malignantly transformed cells. NK cell function is regulated by diverse surface receptors that are both activating and inhibitory. Among them, the homodimeric Ly49 receptors control NK cell cytotoxicity by sensing major histocompatibility complex class I molecules (MHC-I) on target cells. Although crystal structures have been reported for Ly49\/MHC-I complexes, the underlying binding mechanism has not been elucidated. Accordingly, we carried out thermodynamic and kinetic experiments on the interaction of four NK Ly49 receptors (Ly49G, Ly49H, Ly49I and Ly49P) with two MHC-I ligands (H-2Dd and H-2Dk). These Ly49s embrace the structural and functional diversity of the highly polymorphic Ly49 family. Combining surface plasmon resonance, fluorescence anisotropy and far-UV circular dichroism (CD), we determined that the best model to describe both inhibitory and activating Ly49\/MHC-I interactions is one in which the two MHC-I binding sites of the Ly49 homodimer present similar binding constants for the two sites (&#8764;106 M-1) with a slightly positive co-operativity in some cases, and without far-UV CD observable conformational changes. Furthermore, Ly49\/MHC-I interactions are diffusion-controlled and enthalpy-driven. These features stand in marked contrast with the activation-controlled and entropy-driven interaction of Ly49s with the viral immunoevasin m157, which is characterized by strong positive co-operativity and conformational selection. These differences are explained by the distinct structures of Ly49\/MHC-I and Ly49\/m157 complexes. Moreover, they reflect the opposing roles of NK cells to rapidly scan for virally infected cells and of viruses to escape detection using immunoevasins such as m157.","palabras_clave":"MHCI|CITOMEGALOVIRUS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4949,"idioma_id":4,"titulo":"Pluripotent non-tumorigenic adipose tissue-derived Muse cells have immunomodulatory capacity mediated by TGF&#946;1","resumen":"Adult mesenchymal stromalcells (MSC)-based interventions have shown promising results in a broad range of diseases. However, their use has faced limited effectiveness due to low survival rates and susceptibility to environmental stress upon transplantation. Here, we describe cellular and molecular characteristics of Multilineage-differentiating stress-enduring (Muse) cells derived from adipose tissue (AT), a subpopulation of pluripotent stem cells isolated from human lipoaspirates. Muse-AT cells were efficiently obtained by a simple, fast and affordable procedure, avoiding cell sorting and genetic manipulation methods. Muse-AT cells isolated under severe cellular stress, expressed pluripotency stem cell markers and spontaneously differentiated into the three germ lineages. Muse-AT cells grown as spheroids have a limited proliferation rate, a diameter of ~15µm and ultrastructural organization similar to ES cells. Muse-AT cells evidenced a high SSEA-3 expression (~60% of cells) after 7-10 days growing in suspension and did not form teratomas when injected into immune-deficient mice. SSEA-3+-Muse-AT cells expressed CD105, CD29, CD73, HLA-class I, CD44 and CD90 and low levels of HLA-class II, CD45 and CD34. Using LPS-stimulated macrophages and antigen-challenged T cell assays, we have shown that Muse-AT cells have anti-inflammatory activities down-regulating the secretion of pro-inflammatory cytokines, such as IFNg and TNFa. Muse-AT cells spontaneously gained TGFb1 expression that, in a pSMAD2-dependent manner, might prove pivotal in their observed immunoregulatory activity through decreased expression of T-bet in T-cells. Collectively, the present study demonstrated the feasibility and efficiency of obtaining Muse-AT cells that can potentially be harnessed as immunoregulators to treat immune related disorders.","palabras_clave":"STEM CELLS|AT-MUSE|DIABETES|PLURIPOTENT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":4969,"idioma_id":4,"titulo":"Effects of changes in salinity on oxygen and food consumption of the young sub-Antarctic Notothenioid Eleginops maclovinus. Possible implications of their use of an estuarine habitat","resumen":"Salinity is one of the most important structuring factors in the distribution and bioenergetics of estuarine fishes. The aims of this work were to study the distribution of the sub-Antarctic, eurythermic, euryhaline and coastal notothenioid Eleginops maclovinus in Lapataia estuary (Tierra del Fuego National Park), in relation to salinity conditions, and the effect of salinity on the oxygen con- sumption of this species. The spread of the mixing zone of Lapataia was studied and physicochemical properties (conductivity, pH, temperature and salinity) were mea- sured. Distribution of E. maclovinus juveniles was inves- tigated principally by electrofishing in the field. Oxygen consumption of absorptive and post-absorptive young-of- the-year individuals (8?10 cm total length) was analyzed by stop-flow respirometry measurements, performed at three salinities (1, 12 and 30 psu). The intermediate mixing zone is relatively small in this system, showing an exten- sion of *1.5 km upstream from Lapataia Bay. It was found that there was a strong relationship between the mixing zone and the distribution of juveniles of E. maclovinus. No differences were found in the metabolic baseline at different salinities. A punctual feeding provoked a typical SDA response, with a significant higher ingested food and metabolic scope at intermediate salinity (12 psu). An increased scope was reached by increasing the energy intake and not through a decrease in the standard metabolic rate. Under an available food condition, this capacity could result in an increased growth rate at inter- mediate salinity.&nbsp;","palabras_clave":"ELEGINOPS MACLOVINUS|METABOLISM|RESPIROMETRY|SALINITY|ESTUARIAL ZONE|LAPATAIA BAY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5004,"idioma_id":4,"titulo":"The seasonal role of field characteristics on seed-eating bird abundances in agricultural landscapes","resumen":"In temperate agroecosystems, avian responses in abundance and distribution to landscape attributes may be exacerbated by the coupling of natural seasons and farming practices. We assessed the seasonal roles of field type, field use in the surroundings, and distance from a field to the nearest woodlot on the abundance of seed-eating birds in a 225,000km2 study area in the Pampas of central Argentina. During spring-summer and autumn of 2011?2013, we selected 392 fields and used transect samples to collect data on abundance and presence of seed-eating bird species. We recorded a total of 11,579 individuals belonging to 15 seed-eating bird species.We used generalized lineal mixed models to relate bird abundance to field type, field use in the surroundings, and distance to the nearest woodlot. In spring-summer (breeding season) most bird responses were associated with their nesting requirements. Species that build their nests in trees, such as eared doves Zenaida auriculata, picazuro pigeons Patagioenas picazuro, and monk parakeets Myiopsitta monachus, were more abundant in fields closer to woodlots, whereas grassland yellow-finches Sicalis luteola, which nest at areas with tall grasses, were more abundant in fields with livestock use patches in the field surroundings. In autumn (non-breeding season), most bird responses were associated with foraging and refuge needs. The high abundance of eared doves in crop stubbles and the association of pigeons at field surroundings dominated by croplands or at crop stubbles surrounded by livestock use fields revealed the intimate association of these species to sites with high availability of food resources. In addition, both picazuro pigeons and spot-winged pigeons Patagioenas maculosa were associated with woodlots, whichprovide suitable roosting sites. Our results show that in temperate agroecosystems, the relationships between field characteristics and seed-eating bird abundances vary with season.","palabras_clave":"field surroundings|field type|granivorous birds|stubbles|temperate agroecosystems|woodlots"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5081,"idioma_id":5,"titulo":"Estrategias metodológicas para alcanzar desarrollo con inteligencia territorial en un territorio desarticulado. Distrito El Central, San Martín, Mendoza","resumen":"La provincia de Mendoza, en Argentina, está conformada por ambientes netamente diferenciados: de una parte, los oasis que ocupan poco más del 3% de la superficie y concentran más del 90% de la población; de otra, el desierto y la montaña.Los espacios rurales, particularmente aquellos alejados de los centros de decisión, ven acentuadas sus características de desigualdad debido a varias razones; entre otras, la distancia que origina problemas de conexión y conectividad, las condiciones ambientales escasamente propicias, la  débil densidad del hábitat. Ejemplo de ello es el Distrito de El Central, en el extremo NE del Departamento de San Martín, en el E mendocino. A 60 km de la capital de la provincia y a medio camino entre dos cabeceras departamentales, muestra signos evidentes de marginalidad respecto de los centros urbanos más próximos, de desarticulación interna desde el punto de vista socio ? cultural y de perspectivas contrastadas en lo económico-productivo.Para abordar la complejidad de los problemas socio ? territoriales detectados, se aplica la perspectiva de inteligencia territorial (IT), como medio que tienen investigadores y actores de una comunidad para planificar, definir, animar y evaluar políticas y acciones orientadas a obtener un mejor conocimiento del lugar que habitan y con ello alcanzar el desarrollo territorial sustentable. El trabajo que se presenta pone el acento en la secuencia metodológica recorrida, acorde con los principios de la investigación ? acción, adecuándola a las condiciones y necesidades de la situación local concreta. De allí los sucesivos ajustes y modificaciones en las tareas desarrolladas -reuniones comunitarias, entrevistas con referentes institucionales y sociales, encuestas, relevamiento, análisis estadístico y cartográfico, consulta de diversas fuentes de información, talleres de capacitación, entre otras-.Este desafío metodológico que tiene como eje fundamental el diálogo de saberes entre el mundo académico pluridisciplinar y los distintos grupos de actores locales, permite comprender más acabadamente la problemática y las necesidades del distrito, contribuyendo así a encontrar  los medios para  alcanzar el desarrollo sustentable.","palabras_clave":"DESARROLLO SUSTENTABLE|INTELIGENCIA TERRITORIAL|METODOLOGÍA|COMUNIDAD RURAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5085,"idioma_id":4,"titulo":"Androgens modify Wnt agonists\/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia","resumen":"In androgenetic alopecia, androgens impair dermal papillainducedhair follicle stem cell (HFSC) differentiation inhibiting Wntsignaling. Wnt agonists\/antagonists balance was analyzed afterdihydrotestosterone (DHT) stimulation in androgen-sensitive dermalpapilla cells (DPC) cultured as spheroids or monolayer. In both cultureconditions, DHT stimulation downregulated Wnt5a and Wnt10b mRNA while theWnt antagonist Dkk-1 was upregulated. Notably, tissue architecture ofDPC-spheroids lowers Dkk-1 and enhances Wnt agonists´ basal expression;probably contributing to DPC inductivity. The role of Wntagonists\/antagonists as mediators of androgen inhibition of DPC-inducedHFSC differentiation was evaluated. Inductive DPC-conditioned mediumsupplemented with DKK-1 impaired HFSC differentiation mimickingandrogens´ action. This effect was associated with inactivation of Wnt\/&#946;-catenin pathway in differentiating HFSC by both DPC-conditioned media.Moreover, addition of WNT10b to DPC-medium conditioned with DHT, overcameandrogen inhibition of HFSC differentiation. Our results identify DKK1and WNT10b as paracrine factors which modulate the HFSC differentiationinhibition involved in androgen-driven balding.","palabras_clave":"Androgenetic alopecia|Epidermal stem cells|Epithelial-mesenchymal interactions|Dermal papilla|Wnt ligands"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5096,"idioma_id":4,"titulo":"A multi-core computing approach for large-scale multi-label classification (Indexed SCI, IF JCR2015=0.631)","resumen":"Large scale multi-label learning, i.e. the problem of determining the associated set of labels for an instance, is gaining relevance in recent years due to the emergence of several real-world applications. Most notably, the exponential growth of the Social Web where a resource can be labeled by millions of users using one or more tags, i.e. a resource can be associated to several labels at the same time. A well-known approach for multi-label classification is the Binary Relevance (BR) algorithm which trains a binary classifier for each label independently. However, the serial implementation of BR is not suitable for medium or large datasets due to the time and computational resources required for training. For example, training classifiers for mid-size datasets using MULAN implementation of BR might take several weeks. This paper discusses a parallel implementation of the MULAN BR technique that harnesses the computational power of nowadays multi-core processors. Our implementation presents a speed-up in the training phase of up to 12 times when compared to the original MULAN implementation. In addition, the cross-validation technique of MULAN had huge RAM requirements, making it unusable with large datasets. Therefore, we have overcome this limitation by using compact data structures and taking advantage of disk caching. We have also compared our implementation against scikit-learn, a popular tool for data mining and data analysis, showing significant improvements in speed-up.","palabras_clave":"BINARY RELEVANCE CLASSIFICATION|MULTI-CORE PROGRAMMING|PARALLEL CLASSIFICATION|MULTI-LABEL CLASSIFICATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5150,"idioma_id":4,"titulo":"Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern   Argentina","resumen":"Several toxic plants produce lysosomal storage of glycoproteins and mainly nervous clinical disorders. A disease caused by the consumption of Astragalus garbancillo var. garbancillo in sheep from northwestern Argentina is described here. The affected animals presented weight loss, listlessness, staggering gait, and ataxia. Histopathological studies revealed cellular vacuolation in several organs, mainly in the central nervous system (CNS). The material accumulated in the cells was positive for lectins LCA (Lens culinaris agglutinin), sWGA (succinyl?Triticum vulgaris agglutinin), and Con A (Concanavalin A). Finally, the presence of toxic levels of swainsonine was detected in composite samples of the plant. Poisoning by Astragalus garbancillo var. garbancillo was characterized as á-mannosidosis of plant origin.","palabras_clave":"Northwestern Argentina|sheep|swainsonine|Astragalus garbancillo var. garbancillo"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5156,"idioma_id":4,"titulo":"Nonisothermal drying kinetics of biomass fuels by thermogravimetric analysis under oxidative and inert atmosphere","resumen":"n depth investigation of nonisothermal drying kinetic, the first stage of thermal decomposition was conducted using thermogravimetric analysis, to deepen the thermal processes knowledge. The studied biomass wastes were peach pits, marc, and stalk from the canning, jam, and wine industries, respectively. The experimental data have been obtained under oxidative and inert atmospheres at different heating rate (5, 10, and 15 K\/min), to fit to different isoconversional models to describe drying behavior of agro-industrial wastes. These models were evaluated based on different statistical parameters. The best fitting for all experiments were showed by Jander´s model. It is assumed that the three-dimensional diffusion is the drying rate controlling step. The calculated activation energy values are between 20.31 and 48.41 kJ\/mol for all agro-industrial wastes at different experimental conditions. Calculated kinetic parameters for the nonisothermal drying under nitrogen atmosphere are generally higher than those for this phenomenon under air atmosphere. Different physicochemical phenomena are produced, which cause this variation during the drying under different atmospheres. Heating rates have a slight effect on the activation energy since the kinetic rate of drying phenomenon is controlled by the physical transformation occurrence, which is dependent on temperature and it is not on mass dependent..","palabras_clave":"AGRO-INDUSTRIAL WASTES|NONISOTHERMAL DRYING|KINETIC MODELS|THERMOGRAVIMETRIC ANALYSIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5163,"idioma_id":4,"titulo":"Maternal overweight disrupts the sexual maturation of the offspring","resumen":"The aims of the present work were to study the effectof maternal overweight and obesity on the ovarian reserve, folliculardevelopment and ovulation of the offspring, and to assess whether this maternalcondition alters oocyte integrity. To this end, female offspring from rats fedwith standard or cafeteria diet (OSD and OCD respectively) were used. Bodyweight, vaginal opening and estrous cycle were recorded and ovaries wereobtained on the day of the second estrus. In addition, ovarian weight, ovulationrate (measured by the number of oocytes within oviducts), folliculardevelopment (determined by histology) and oocyte integrity were examined. OCDrats were divided in two groups: those from rats with 17% and 28% of overweight(OCD17 and OCD28 respectively). Both OCD groups showed higher body weight, butOCD28 also exhibited early vaginal opening and higher ovarian weight andglycemia at euthanasia compared with OSD rats. Both OCD17 and OCD28 had lowernumber of primordial and primary follicles, and only OCD28 exhibited lowernumber of antral follicles, all compared with OSD rats. In addition, both OCD17and OCD28 had higher ovulation rate than controls, and OCD28 had lower numberof healthy oocytes, which, in turn, exhibited morphological alterations such aslarger perivitelline space and zona pellucida than those from control animals. Theseresults suggest that maternal overweight may severely affect the reproductiveability of the offspring, likely as a result of altering the organogenesis.","palabras_clave":"Overweight|Sexual Maturation|Ovulation|Follicular Growth"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5236,"idioma_id":4,"titulo":"N-3 FATTY ACIDS REDUCED TRANS FATTY ACIDS RETENTION AND INCREASED DOCOSAHEXAENOIC ACID LEVELS IN BRAIN","resumen":"Thelevels of docosahexaenoic acid (DHA, 22:6n-3) and arachidonic acid (AA,20:4n-6) are critical for the normal structure and function of the brain. Transfatty acids (TFA) and the source of the dietary fatty acids (FA) interfere withlong-chain polyunsaturated fatty acids (LC-PUFA) biosynthesis. The aim was toinvestigate the effect of TFA supplementation in diets containing differentproportions of n-9, n-6 and n-3 FA on the brain FA profile, including retentionof TFA, LC-PUFA levels and n-6\/n-3 PUFA ratios. These parameters were alsoinvestigated in liver, considering that LC-PUFA are mainly bioconverted fromtheir dietary precursors in this tissue and transported by serum to the brain.Also, stearoyl-CoA desaturase 1 (SCD1) and sterol regulatory element-bindingprotein 1-c (SREBP-1c) gene expressions were evaluated. Male CF1 mice were fed(16 weeks) diets containing different oils (olive, corn and rapeseed) withdistinct proportions of n-9, n-6 and n-3 FA (55.2\/17.2\/0.7; 32.0\/51.3\/0.9 and61.1\/18.4\/8.6) respectively substituted or not with 0.75% of TFA. FAcomposition of brain, liver and serum was assessed by gas chromatography. TFAwere incorporated into, and therefore retained in brain, liver and serum.However, the magnitude of retention was dependent on the tissue and type ofisomer. In the brain, total TFA retention was lower than 1% in all diets.Dietary n-3 PUFA decreased TFA retention and increased DHA accretion in brain.The results underscore the importance of the type of dietary FA on the retentionof TFA in brain and also on the changes of the FA profile.","palabras_clave":"TRANS FATTY ACIDS|BRAIN|FATTY ACIDS PROFILE|OLIVE OIL|RAPEESED OIL|CORN OIL|LONG-CHAIN POLYUNSATURATED FATTY ACIDS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5246,"idioma_id":4,"titulo":"AQP2-induced acceleration of renal cell proliferation involves the activation of a regulatory volume increase mechanism dependent on NHE2","resumen":"We have previously shown in renal cells that expression of the water channel Aquaporin 2 (AQP2) increases the rate of cell proliferation by shortening the transit time through the S and G2 \/M phases of the cell cycle. This acceleration is due, at least in part, to a down-regulation of regulatory volume decrease (RVD) mechanisms when volume needs to be increased in order to proceed into the S phase. We hypothesize that in order to increase cell volume, RVD mechanisms may be overtaken by regulatory volume increase mechanisms (RVI). In this study, we investigated if the isoform 2 of the Na+ \/H+ exchanger (NHE2), the main ion transporter involved in RVI responses, contributed to the AQP2-increased renal cell proliferation. Three cortical collecting duct cell lines were used: WT-RCCD1 (not expressing AQPs), AQP2-RCCD1 (transfected with AQP2) and mpkCCDc14 (with inducible AQP2 expression). We here demonstrate, for the first time, that both NHE2 protein activity and expression was increased in AQP2-expressing cells. NHE2 inhibition decreased cell proliferation and delayed cell cycle progression by slowing S and G2 \/M phases only if AQP2 is expressed. Finally, we observed that only in AQP2-expressing cells a NHE2-dependent RVI response was activated in the S phase. These observations suggest that the AQP2-increased proliferation involves the activation of a regulatory volume increase mechanism dependent on NHE2. Therefore, we propose that the accelerated proliferation of AQP2-expressing cells requires a coordinated modulation of the RVD\/RVI activity that contributes to cell volume changes during cell cycle progression.","palabras_clave":"AQP2|CELL PROLIFERATION|NHE2|REGULATORY VOLUME INCREASE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5251,"idioma_id":5,"titulo":"VALIDACIÓN DE LA ESTIMACIÓN DE PRECIPITACIÓN POR SATÉLITE APLICANDO LA TÉCNICA HIDROESTIMADOR","resumen":"La técnica Hidroestimador para estimar precipitación por satélite fue desarrollada originalmente en la National Oceanic and Atmospheric Administration\/National Environmental Satellite, Data, and Information Service (NOAA\/NESDIS). En el Servicio Meteorológico Nacional (SMN) de Argentina, esta técnica volvió a estar operativa a partir de septiembre de 2013, y utiliza imágenes del canal infrarrojo térmico del satélite GOES-13 e información de variables meteorológicas pronosticadas por el modelo ETA. Los píxeles de lluvia y no lluvia, se separan de acuerdo a un valor construido con la media y la desviación estándar de la temperatura de brillo en un área centrada en el píxel de interés. Las nubes en un determinado píxel, producen precipitación si poseen topes más fríos que la media de los píxeles circundantes. La tasa de precipitación, se ajusta teniendo en cuenta la humedad del entorno, a partir de datos de humedadrelativa y agua precipitable de los modelos de pronóstico numérico. En la página web del SMN, los mapas de precipitación instantánea están disponibles cada 30 minutos, y los mapas de precipitación acumulada cada 6, 12 y 24 horas, con una resolución espacial de 4 km.Actualmente, se lleva adelante el seguimiento y la aplicación de diferentes cambios en el algoritmo con el fin de mejorar esta estimación, que incluyen una versión asociada al filtrado de nubes cirrus, como también la comparación con una versión que no discrimina clusters de nubes.En este trabajo, se realiza una validación cada 24 horas de la versión operativa y las versiones de prueba de la estimación de precipitación, teniendo en cuenta el periodo de un año completo de datos disponibles. Esta evaluación integral, consiste en el análisis de diferentes estadísticos en forma puntual, y en la red completa de estaciones pluviométricas disponible en tiempo real.En el sur de Sudamérica, que presenta diferentes regímenes de precipitación, se pudo observar en la validación diaria para los meses disponibles, que el Hidroestimador tiende a subestimar la precipitación en los eventos de precipitación débil, tal como mostraron Salio et al. (2015), peroaparece una sobrestimación importante en los eventos de precipitación más intensa.","palabras_clave":"precipitacion|hidroestimador |Sudamerica"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5294,"idioma_id":4,"titulo":"Evaluation of habitat requirements of small rodents and effectiveness of an ecologically-based management in a hantavirus-endemic natural protected area in Argentina","resumen":"Hantavirus Pulmonary Syndrome is a severe cardio pulmonary disease transmitted to humans by sylvan rodents found in natural and rural environments. Disease transmission is closely linked to the ecology of animal reservoirs and abiotic factors such as habitat characteristics, season, or climatic conditions. The main goals of this research were: to determine the biotic and abiotic factors affecting richness and abundance of rodent species at different spatial scales, to evaluate different methodologies for studying population of small rodents, and to describe and analyze an ecologically-based rodent management experience in a highly touristic area. A four-year study of small rodent ecology was conducted between April 2007 and August 2011 in the most relevant habitats of El Palmar National Park, Argentina. Management included a wide range of control and prevention measures including poisoning, culling and habitat modification. A total of 172 individuals of five species were captured with a trapping effort of 13860 traps-nights (1.24 individuals\/100 traps-nights). Five rodent species were captured including two hantavirus-host species, Oligoryzomys nigripes and Akodon azarae. O. nigripes, host of a hantavirus which is pathogenic in humans, was the most abundant species and the only one found in all the studied habitats. Our results are inconsistent with the dilution effect hypothesis. This study demonstrates that sylvan rodent species, including the hantavirus-host species, have distinct local habitat selection and temporal variation patterns in abundance, which may influence the risk of human exposure to hantavirus and may have practical implications for disease transmission as well as for reservoir management.","palabras_clave":"ABUNDANCE|DISEASE PREVENTION|HABITAT USE|POPULATION DYNAMICS|ZOONOSIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5336,"idioma_id":4,"titulo":"Call variability, stereotypy and relationships in syntopy of tetraploid common lesser escuerzo (Anura: genus Odontophrynus)","resumen":"We studied patternsof the geographic variation of mating calls of the common lesser escuerzo Odontophrynus americanus includingpopulations living in syntopy with the closely related O. cordobae and adjacent allopatric populations. The dominantfrequency, pulse rate, call duration and pulses\/call showed the lowestintra-individual variation (CV&lt;3%). The discriminant function analysis (DFA)assigned 88% of all calls to the correct individual, indicating that theadvertisement calls of O. americanusare individually distinctive. Call duration, pulses per call and the dominantfrequency were likely related to individual distinctiveness. Pulse rate and pulsetemporal parameters related consistently showed the lowest values of CVb\/CVwratio and could be considered key properties for species recognition in O. americanus. We found a greater calldivergence between species in syntopy than in allopatry in terms of the pulserate and particularly the interpulse interval. These resultsappear to be consistent with a pattern of reproductive character displacement. Further studies testingfemale selectivity should be essentialto evaluate whether acoustic differencesobserved between syntopic and allopatric populations are biologically significantand if there are differences in selectivity between such areas. ","palabras_clave":"ADVERTISEMENT CALL|ANURAN COMMUNICATION|BIOACOUSTICS|CHARACTER DISPLACEMENT|GEOGRAPHIC VARIATION|ODONTOPHRYNUS|SYNTOPY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5344,"idioma_id":4,"titulo":"Aggregations and reproductive events of the narrownose smooth hound shark, Mustelus schmitti, in relation to temperature and depth in coastal waters of the southwestern Atlantic Ocean (38-42° S)","resumen":"Knowledge of environmental influence on reproductive dynamics in chondrichthyans is critical for effective management. The present study assessed the potential influences of temperature and depth on aggregations and reproductive events of the narrownose smooth-hound shark (Mustelus schmitti), using an analysis criterion based on the co-occurrence of different reproductive stages. Data were collected from 363 sample sites during six research surveys, covering an area of 47 744 km2 along the coast (38?42°S, depth of ,50 m). Aggregations of M. schmitti adults were mostly associated with the warmer spring surveys, with the aggregation sites being significantly warmer than those of non-aggregation. Evidence of pupping and ovulation was observed, almost simultaneously, during all spring surveys. However, the occurrence of these reproductive events showed a clear interannual variability pattern that was significantly explained by water temperature. Particularly, the occurrence of ovulation was associated with temperatures above 16?17°C. These results suggest that M. schmitti adults may follow the warming gradient along the environment and, thus, they aggregate in shallow and productive waters during the course of spring. Their reproductive events could be induced by temperature increase. This scenario suggests that changes in the patterns of bottom temperature may be important drivers of the reproductive dynamics of M. schmitti.","palabras_clave":"Coastal ecosystem|Elasmobranchs|environmental cues|reproductive aggregations"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5353,"idioma_id":4,"titulo":"Screening of new secretory cellulases from different supernatants of white rot fungi from Misiones, Argentina","resumen":"Cellulases hydrolyse the cellulose chain into single sugars efficiently. These sugars can be fermented in the bioethanol process, a source of renewable energy. Misiones rainforest is one of the most biodiverse systems on the planet subtropical ecoregions, which is the most probable site to find new fungal strains with potential for degrading cellulose through cellulases. The aim of this work was to find an efficient cellulolytic microorganism through the exploration of native white rot fungi from Misiones. From the qualitative screening 11 fungal strains were selected. The quantitative analysis revealed that the isolated LBM 033 was the best cellulases producer, reaching 57, 226 and 387 U\/l of cellobiohydrolase, &#946;-glucosidase and endoglucanase activity, respectively. The zymograms showed that the molecular mass of most of the endoglucanases ranged from 69 to 88 kDa and the molecular mass of most of the cellobiohydrolases was 45 kDa. The search of new cellulases of secretory organisms should lead to an efficient degradation ofcellulosic materials, and thus facilitating potential applications in the production of bioenergy from lignocellulosic biomass","palabras_clave":"ENDOGLUCANASE|CELLOBIOHYDROLASE|GLUCOSIDASE|WHITE ROT FUNGI"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5387,"idioma_id":4,"titulo":"Cumulative effects of volcanic ash on the food preferences of 2 Orthopteran species","resumen":"Inert dusts are an early form of insecticide which is still in use. One of the most common inert dusts is volcanic ash. In order to study the reaction of rangeland grasshoppers, Dichroplus vittigerum (Acrididae) and a katydid, Burgilis sp. mendosensis (Phaneropteridae), to the presence of volcanic ash in their food sources and how this reaction changed as a function of time, we conducted paired preference tests between clean leaves of their preferred host plant and leaves exposed to volcanic ash of different grain size. The behavioral response was measured as the rating on the Thurstonian preference scale of leaves with ash in relation to clean leaves. The results showed that the avoidance of volcanic ash increased as a function of time in both species. Both species studied are occasionally exposed to volcanic activity, and come from an area in which a volcanic eruption had recently occurred. As their populations not only did not decrease after the ash fall, but increased to become major pests, we propose that some behavioral responses such as avoidance of places with ash, work as tolerance mechanism to inert dusts exposure.","palabras_clave":"BURGILIS MENDOSENSIS|DICHROPLUS VITTIGERUM|INERT DUST|PREFERENCE TEST|THURSTONE SCALE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5389,"idioma_id":4,"titulo":"Heterodimer magnetic  > nanoparticles-carbon nanotubes with tunable magnetic properties","resumen":"This work proposes an easy and scalable convergent synthesis method to obtain heterodimers formed by multi-walled carbon nanotubes and magnetic nanoparticles via carbon-nitrogen bonds. Magnetic nanoparticles were synthesized by solvothermal method. Heterodimers were characterized by X-ray diffraction, Fourier Transform Infrared Spectroscopy, Transmission Electronic Microscopy and magnetic properties. The magnetic nanoparticles have a mixed crystal structure, mostly formed by maghemite and a small fraction of hematite. Infrared Spectroscopy and TransmissionElectronic Microscopy confirm the formation of heterodimer magnetic nanoparticles?carbon nanotubes via covalent bonds. Magnetic measurement indicates that it is possible to adjust the magnetic response according to the final application.","palabras_clave":"HETERODIMER|MAGNETIC NANOCOMPOSITE|CARBON NANOTUBE|MAGHEMITE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5390,"idioma_id":4,"titulo":"Effect of volcanic ash deposition on length and radial growths of a deciduous montane tree ( Nothofagus pumilio )","resumen":"Extreme environmental events such as volcanic eruptions can trigger plant responses that largelyexceed those recorded for moderate-intensity disturbances. We assessed the effects of the June 2011 eruption ofthe Puyehue ? Cordon Caulle volcano on the length and radial growths of juvenile Nothofagus pumilio trees attwo sites located 20 (with >40 cm ash accretion) and 75 (without ash) km from the volcano. Variations in lengthand radial growth were evaluated for the periods 1999?2013 and 1993?2013 respectively; pre- and post-eruptiongrowth rates were computed. The length growth of the N. pumilio trees located close to the volcano increasedsignificantly after the eruption: shoot extensions during the growing season after the eruption were, on average,two to three times longer than average according to ontogenetic growth trends. Variations in radial growth afterthe eruption were comparatively less noticeable than those in length growth. No significant effects of the eruptionwere observed in those trees located 75 km from the volcano. In order to explain the exceptionally positiveresponse of N. pumilio?s length growth to the volcanic eruption, three non-exclusive explanations were proposed:(i) thick ash layers increase water retention in the soil; (ii) volcanic ash facilitates the access of plants to nutrients;and (iii) volcanic ashes decrease herbivory and competition. The comparatively lower sensitivity of radialgrowth to this extreme volcanic event is also noteworthy. These findings highlight the need to further examinehow large-scale volcanic events influence structure and\/or functioning of ecosystem in the Patagonian forest.","palabras_clave":"LENGTH GROWTH|RADIAL GROWTH|NOTHOFAGUS PUMILIO|DISTURBANCE|VOLCANIC ERUPTION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5465,"idioma_id":4,"titulo":"Control of agitation rate and aeration for enhanced polygalacturonase production in submerged fermentation by Aspergillus sojae using agro-industrial wastes","resumen":"BACKGROUND: The koji mold Aspergillus sojae, an industrially important microorganism, canproduce high levels of pectinases utilizing agro-industrial wastes. This studyintroduces apricot and peach pomace, two agro-industrial wastes barelyconsidered as raw material for the generation of value?added products, andfocuses on its utilization together with orange peel for polygalacturonase productionin submerged cultures using A. sojae.RESULTS: A Doehlert response surface methodologydesign conducted in shake flasks and applied individually with these threeby-products led to 60 ? 80 U\/ml polygalacturonase activity. In bioreactorstudies performed with a mixture of apricot pomace and orange peel, by fixingstirrer speed to 600 rpm and cascading airflow to the dissolved oxygen tensionup to 1.7 vvm, oxygen limitation problems were overcome and polygalacturonaseactivity values of 380 U\/ml were achieved.CONCLUSION: A simple and efficient strategy to minimizeoxygen limitation with the lowest possible shear stress is provided forstirred-tank bioreactors working with highly viscous broths, so as toultimately enhance microbial enzyme production. The polygalacturonase activityyields obtained in our study are among the highest reported in the literature.","palabras_clave":"Batch fermentation|Oxygen limitation|Response surface design|Agro-industrial wastes"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5468,"idioma_id":4,"titulo":"The polycyclic scoria cones of the Antofagasta de la Sierra basin, Southern  Puna Plateau, Argentina","resumen":"Despite the existence of several works focused on the geodynamic implications of the recent Southern Puna mafic magmatism, volcanologic and stratigraphic studies are still little developed. This paper presents a detailed map of two well-preserved Quaternary scoria cones, showing their complex stratigraphy.  Complementary morphometric, morphostructural, petrographic and geochemical data were used to reconstruct the evolution of both volcanoes. The occurrence of more than one eruption at each volcano was inferred by recognition of temporal hiatuses using a morpho-stratigraphic criteria. The polycyclic nature of both scoria cones could be related to a combination of a high input  magma in response to lithospheric delamination, a favourable regional stress field and  interaction of rising magma with pre-existing faults. The youngest eruptions in both  volcanoes were complex with shifts of the  eruptive style from violent strombolian to  hawaiian\/strombolian phases and probably lasted a few years. The explosive activity was  accompanied by the emission of lava flows from lateral vents. During the waning stages of the eruptions phreatomagmatic activity was triggered. The occurrence of more than one eruption in a single scoria cone and the changes in the eruptive style during long lasting eruptions are important topics for volcanic hazard assessment in the Southern Puna.","palabras_clave":"Mafic Volcanism|Volcanotectonic Interplay|Morpho-stratigraphy|Litho-stratigraphy|Complex volcanic evolution"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5483,"idioma_id":5,"titulo":"Reconociendo el carácter multifacético de la educación: los determinantes de los logros cognitivos y no-cognitivos en la escuela media argentina","resumen":"Para brindar herramientas que permitan a las personas desarrollar todo su potencial, la educación debería no sólo proveer conocimientos y aptitudes, sino también contribuir a la formación de actitudes, valores y disposiciones positivas. Interesa por ello comprender mejor el desarrollo de distintas competencias cognitivas y no-cognitivas, proceso complejo que depende de factores personales, familiares, escolares y contextuales. Este trabajo presenta un modelo de regresión multinivel multivariado que analiza simultáneamente los determinantes de dos resultados alcanzados por los alumnos argentinos participantes de PISA-2012: uno cognitivo ?la nota obtenida en la prueba de Matemáticas? y uno no-cognitivo ?la apertura hacia la resolución de problemas?. Los resultados sugieren que los dos tipos de logros difieren en sus factores explicativos; y que los atributos escolares son menos relevantes que los individuales en la determinación de ambos, pero que existe un margen para mejorar su desarrollo desde la escuela.","palabras_clave":"LOGROS EDUCATIVOS|COGNITIVO|NO-COGNITIVO|ANÁLISIS MULTINIVEL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5492,"idioma_id":4,"titulo":"Morphotypes of the lacustrine ostracod Limnocythere rionegroensis Cusminsky & Whatley from Patagonia, Argentina, shaped by aquatic environments","resumen":"This study describes and quantifies morphological valve traits of the ostracod Limnocythere rionegroensis from Patagonian steppe lakes and explores their association with lake water characteristics. Surface ornamentation was examined by scanning electron and transmitted light microscopy, and valve size and shape were analyzed using morphometric techniques. Limnocythere rionegroensis shows remarkable variations in surface ornamentation, based on which three morphotypes (MI, MII, and MIII) were identified. Valves of morphotypes MI and MIII are larger, show slight to moderate external reticulation, and a higher shape variability, whereas MII is characterized by a very conspicuous reticulation, lower shape variability, and smaller valves. Outline analysis yielded a great shape disparity related to the dorsal margin slope. MI was found in sexual populations from euhaline to mesohaline ephemeral lake; MII occurs in parthenogenetic populations from mesohaline to oligohaline permanent or ephemeral lakes; and MIII, from both sexual and asexual populations, inhabits a broad range of environmental conditions in terms of salinity and stability. Limnocythere rionegroensis intraspecific variations may be caused by environmental parameters and genetic factors associated to reproductive strategies. These results contribute to the knowledge of extant L. rionegroensis morphological variability and provide additional clues to improve the environmental interpretation of fossil assemblages.","palabras_clave":"OSTRACODA|LIMNOCYTHERE|ORNAMENTATION|GEOMETRIC|MORPHOMETRY|PATAGONIAN|STEPPE|LAKES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5496,"idioma_id":4,"titulo":"Inducible ablation of dopamine D2 receptors in adult mice impairs locomotion, motor skill learning and leads to severe parkinsonism","resumen":"Motor execution and planning are tightly regulated by dopamine D1 and D2 receptors present in basal ganglia circuits. Although stimulation of D1 receptors is known to enhance motor function, the global effect of D2 receptor (D2R) stimulation or blockade remains highly controversial, with studies showing increasing, decreasing or no changes in motor activity. Moreover, pharmacological and genetic attempts to block or eliminate D2R have led to controversial results that questioned the importance of D2R in motor function. In this study, we generated an inducible Drd2 null-allele mouse strain that circumvented developmental compensations found in constitutive Drd2 -\/- mice and allowed us to directly evaluate the participation of D2R in spontaneous locomotor activity and motor learning. We have found that loss of D2R during adulthood causes severe motor impairments, including hypolocomotion, deficits in motor coordination, impaired learning of new motor routines and spontaneous catatonia. Moreover, severe motor impairment, resting tremor and abnormal gait and posture, phenotypes reminiscent of Parkinson´s disease, were evident when the mutation was induced in aged mice. Altogether, the conditional Drd2 knockout model studied here revealed the overall fundamental contribution of D2R in motor functions and explains some of the side effects elicited by D2R blockers when used in neurological and psychiatric conditions, including schizophrenia, bipolar disorder, Tourette´s syndrome, dementia, alcohol-induced delusions and obsessive-compulsive disorder.","palabras_clave":"D2 receptor|inducible knockout mouse|aged mice|parkinsonism"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5525,"idioma_id":4,"titulo":"Transfection of bovine fetal fibroblast with polyethylenimine (PEI) nanoparticles: effect of particle size and presence of fetal bovine serum on transgene delivery and cytotoxicity","resumen":"The development of efficient transfection protocols for livestock cells is crucial for implementation of cell-based transgenic methods to produce genetically modified animals. We synthetized fully deacylated linear 22, 87 and 217&nbsp;kDa polyethylenimine (PEI) nanoparticles and compared their transfection efficiency and cytotoxicity to commercial branched 25&nbsp;kDa PEI and linear 58&nbsp;kDa poly(allylamine) hydrochloride. We studied the effect of PEI size and presence of serum on transfection efficiency on primary cultures of bovine fetal fibroblasts and established cells lines (HEK 293 and Hep G2). We found that transfection efficiency was affected mainly by polymer\/pDNA ratio and DNA concentration and in less extent by PEI MW. In bovine fibroblast, preincubation of PEI nanoparticles with fetal bovine serum (FBS) greatly increased percentage of cells expressing the transgene (up to 82%) while significantly decreased the polymer cytotoxic effect. 87 and 217&nbsp;kDa PEI rendered the highest transfection rates in HEK 293 and Hep G2 cell lines (&gt;50% transfected cells) with minimal cell toxicity. In conclusion, our results indicate that fully deacylated PEI of 87 and 217&nbsp;kDa are useful DNA vehicles for non-viral transfection of primary cultures of bovine fetal fibroblast and HEK 293 and Hep G2 cell lines.","palabras_clave":"transgenesis|cattle|fibroblasts|polyethylenimine"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5529,"idioma_id":4,"titulo":"New compositional data supports a decentralized model of artefact production and circulation in the pre-Columbian Andes","resumen":"The circulation and exchange of goods and resources at various scales have long been considered central to the understanding of complex societies, and the Andes have provided a fertile ground for investigating this process. However, long-standing archaeological emphasis on typological analysis, although helpful to hypothesize the direction of contacts, has left important aspects of ancient exchange open to speculation. To improve understanding of ancient exchange practices and their potential role in structuring alliances, we examine material exchanges in northwest Argentina (part of the south-central Andes) during 400 BC to AD 1000 (part of the regional Formative Period), with a multianalytical approach (petrography, instrumental neutron activation analysis, laser ablation inductively coupled plasma mass spectrometry) to artifacts previously studied separately. We assess the standard centralized model of interaction vs. a decentralized model through the largest provenance database available to date in the region. The results show: (i) intervalley heterogeneity of clays and fabrics for ordinary wares; (ii) intervalley homogeneity of clays and fabrics for a wide range of decoratedwares (e.g., painted Ci-naga); (iii) selective circulation of two distinct polychrome wares (Vaquer-as and Condorhuasi); (iv) generalized access to obsidian from one major source and various minor sources; and (v) selective circulation of volcanic rock tools from a single source. These trends reflect the multiple and conflicting demands experienced by people in small-scale societies, which may be difficult to capitalize by aspiring elites. The study undermines centralized narratives of exchange for this period, offering a new platform for understanding ancient exchange based on actual material transfers, both in the Andes and beyond.","palabras_clave":"Andes|archaeology|exchange|social complexity|compositional analysis"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5553,"idioma_id":4,"titulo":"Antibacterial activity of gelatin\/copper (II)-exchanged montmorillonite films","resumen":"Cu (II) - exchanged montmorillonite (Cu2+ 18 MMt) was prepared, characterized and introduced into a bovine gelatin (Ge) matrix via a dissolution-intercalation method to get antibacterial nanocomposite films. The maximum amount of exchanged cation didnot exceed the cation exchange capacity of the pristine montmorillonite (Na+ MMt), as assessed by energy dispersive X-ray (EDX) spectroscopy. Cu2+ 22 MMt showed antibacterial activity in vitro against Escherichia coli O157:H7 (Gram-negative) and Listeria monocytogenes (Gram-positive) as revealed by the agar disc-diffusion assay. The dispersion of clays in Ge films was monitored by X-ray diffraction (XRD) and Scanning Electron Microscopy (SEM). Blending gelatin with 5 % w\/w of clay increased the tensile strength of the nanocomposite films in around 280 % while the elongation atbreak and the water vapor permeability decreased in about 42 and 30 %, respectively,regardless of the cation in clay. The Ge\/Cu2+ 29 MMt film exhibited antibacterial effectiveness against both pathogens tested under the same conditions, demonstrating a stronger effect on L. monocytogenes than on E. coli O157:H7, since the cell wall of the latter differs significantly and such difference could influence their vulnerability and response to the active films. Therefore, the incorporation of low clay levels as a vehicle for copper ions into gelatin matrix has demonstrated to be a good method for developing functional materials that can be potentially applied to the design of foodcontact items-","palabras_clave":"BOVINE GELATIN|CUPRIC IONS|MONTMORILLONITE|NANOCOMPOSITE|ACTIVE FILM|ANTIMICROBIAL ACTIVITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5570,"idioma_id":4,"titulo":"Bacteriomes of the corn leafhopper, Dalbulus maidis (DeLong & Wolcott, 1923) (Insecta, Hemiptera, Cicadellidae: Deltocephalinae) harbor Sulcia symbiont: molecular characterization, ultrastructure and transovarial transmission","resumen":"In this study, we surveyed the bacteriome-associated microbiota of the corn leafhopper Dalbulus maidis by means of histological, ultrastructural, and molecular analyses. Amplification and sequencing of 16S rDNA genes revealed that the endosymbiont ?Candidatus Sulcia muelleri? (Phylum Bacteroidetes) resides in bacteriomes of D. maidis. Phylogenetic analysis showed that the sequence was closely allied to others found in representatives of the subfamily Deltocephalinae. We failed to amplify other sequences as ?Candidatus Nasuia deltocephalinicola,? a co-primary symbiont frequently associated to deltocephaline leafhoppers. In addition, a metagenetic analysis carried out in order to investigate the presence of other bacteriome-associated bacteria of D. maidis showed that the sequence of Sulcia accounted for 98.56 % of all the sequences. Histological and ultrastructural observations showed that microorganisms harbored in bacteriomes (central syncytium and cytoplasm of uninucleate bacteriocytes) look like others Sulcia described in hemipteran species and they were transovarially transmitted from mother to offspring which is typical of obligate endosymbionts. The only presence of Sulcia in the bacteriomes of D. maidis was discussed.","palabras_clave":"CANDIDATUS SULCIA MULLERI  .  |BACTERIOMES|CORN STUNT|CORN LEAFHOPPER|OBLIGATE ENDOSYMBIONTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5580,"idioma_id":4,"titulo":"Late Prehistoric High-Altitude Hunter-Gatherer Residential Occupations in the Argentine Southern Andes","resumen":"Test excavations at Risco de los Indios (RDLI), a site at 2480 masl with 29 residential features and well-developed midden containing abundant floral, faunal, lithic and ceramic materials are described. Analyses indicate the site was intensively used ca. 500 CAL B.P. as a residential base for multiple family groups focused on hunting guanaco, supplemented by locally-available wild flora and fauna as well as domestic beans transported from the lowlands. Ceramics and obsidian indicate these groups were highly mobile and in contact with groups on the eastern and southern margins of the Andes. These patterns compare favorably to those seen in the region?s other high altitude villages. It appears the development of these patterns coincided with population increase and economic intensification in the lowlands ca 2000 CAL B.P. and that the move to slightly lower elevation settings like RDLI may have been conditioned by the onset of the Little Ice Age.","palabras_clave":"High-Altitude|Hunter-Gatherer|Residential|Late Prehistoric"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5659,"idioma_id":4,"titulo":"Sufficient dimension reduction for censored predictors","resumen":"Motivated by a study conducted to evaluate the associations of 51 inflammatory markers and lung cancer risk, we propose several approaches of varying computational complexity for analyzing multiple correlated markers that are also censored due to lower and\/or upper limits of detection, using likelihood-based sufficient dimension reduction (SDR) methods. We extend the theory and the likelihood-based SDR framework in two ways: (a) we accommodate censored predictors directly in the likelihood, and (b) we incorporate variable selection. We find linear combinations that contain all the information that the correlated markers have on an outcome variable (i.e. are sufficient for modeling and prediction of the outcome) while accounting for censoring of the markers. These methods  yield efficient estimators and can be applied to any type of outcome, including continuous and categorical outcomes.  We illustrate and compare all methods using data from the motivating study and in simulations. We found that explicitly accounting for the censoring in the likelihood set-up can lead to appreciable gains in efficiency and prediction accuracy, and also outperformed multiple imputations combined with standard SDR.","palabras_clave":"sufficient reduction|censored predictors"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5661,"idioma_id":4,"titulo":"RISK ANALYSIS OF AGRO-INDUSTRIAL WASTES GASIFICATION IN FLUIDIZED BED","resumen":"Thermochemical conversion processes used to convert agro-industrial wastes are increasingly common, for economic and environmental reasons. Due to CO2 accumulation in the atmosphere, biomass wastes gasification has the potential to significantly contribute to more environmentally friendly energy services. Fluidized bed reactor is currently one of the most promising technologies of energy conversion because of its advantages. However, the challenges and approaches to the safety and risk management for the syngas production using the fluidized bed reactor have been far from sufficiently examined. This work presents the identification of different risk using the MAD-MOSAR method, recognizing the short and long scenarios. Different risk hazards for the biomass gasification in fluidized bed reactor were evaluated using the Life Cycle Risk Assessment. The most important subsystems involved in the long scenario of damage and injury are a supply of natural gas and compressed air and\/or steam, fluidized bed reactor gasifier, syngas cooling and cleaning systems and gas engine generator.","palabras_clave":"industrial waste|gasification|fluidized bed"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5669,"idioma_id":4,"titulo":"Some Results for the (Signless) Laplacian  Resolvent","resumen":"The recently introduced concept of resolvent energy of a graph is based on the adjacency matrix. We now consider the analogous resolvent energies based on the Laplacian and signless Laplacian matrices, and determine some of their basic properties.","palabras_clave":"Laplacian Resolvent|Graph Theory|Energy of a Graph|Resolvent Energy"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5686,"idioma_id":4,"titulo":"'Multiplex PCR designed to  differentiate C. glabrata complex species'","resumen":"Background: No phenotypic methods are available to unequivocally differentiate species within theCandida glabrata complex.Aims: To develop a new multiplex PCR method to differentiate between the three species ofthe C. glabrataspecies complex, as well as using it to study a C. glabrata collection to discover strains of the newlydescribed species.Methods: The method was developed based on the Internal Transcribed Spacer (ITS) sequencedifferences between the species. It was validated by using a blinded collection of strains and, finally,the new molecular method was used to study a collection of 192 C. glabrata species complex strains. Theobtained results were compared with ITS sequencing.Results: The proposed method showed 100% concordance with ITS sequencing and proved to be effectivefor clinical and epidemiological applications. Two Candida bracarensis and three Candida nivariensis werefound out of the 192 studied strains (0.93% and 1.40% prevalence, respectively).Conclusions: A fast, inexpensive, robust and highly reproducible multiplex PCR method is presented. Itsusefulness is demonstrated by studying a large collection of C. glabrata sensu lato strains","palabras_clave":"CANDIDA GLABRATA COMPLEX|MOLECULAR IDENTIFICATION|CANDIDA NIVARIENSIS|CANDIDA BRACARENSIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5688,"idioma_id":4,"titulo":"Modelling agaricoid fungi distribution in Andean forests of Patagonia","resumen":"Abstract:Agaricoid fungi of Subantartic forests have been vastly studied at a taxonomical and, to less extent, ecological level. These historical approaches have left large amounts of presence-only occurrences of several endemic species of the Andean region. Since sampling season in Patagonia is reduced to a minimum because of its large extension and climate conditions that govern the region, it is essential to focus on locations where subjects of study are present. Knowledge of patterns of fungal distributions can help lead future forest management investments as well as to guide efforts to delimit fungal hot-spots areas of conservation. The aim of the present work was to assess the potential distribution of a selection of 9 saprophytic and 9 ectomycorrhyzic gilled fungi based on their abundance, seasonality, occurrences in bibliography and detectability. Eighty localities were georreferenced for 260 occurrences of the species modelled. The ectomycorrhyzic Entoloma patagonicum presents the most restricted distribution among all species studied while Psathyrella falklandica, saprophytic, has the most widespread distribution. Despite having different nutritional requirements, all species studied exhibit a very similar dependence with mean precipitation of the driest month and similar potential distributions. Distribution maps are provided for each species. Discussion on the dynamics and extent of fungal species distribution in Patagonia is also provided.","palabras_clave":"Agaricales|Species distribution models|Maxent|Nothofagus"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5707,"idioma_id":4,"titulo":"Low frequency variability and trends in centennial precipitation stations in southern South America","resumen":"Southern South America (SSA), considered as the continental region south of 20°S, has experienced significant precipitation variability and trends in the last decades. This paper uses monthly quality-controlled precipitation data from rainfall stations with continuous observations during at least 100 years to quantify long-term trends as well as interannual-to-centennial variability. Several statistical methods are applied to the data, primarily to detect jumps and look for changes due to relocation of the gauge stations, as well as to identify significant trends. Most of the regions have registered an increase in annual rainfall, largely attributable to changes in the warm season. On the other hand, during winter most stations in Argentina and Brazil do not have significant trends, although eastern Patagonia registered an increase in precipitation and Chile, a marked decrease in rainfall.In order to look into the physical mechanisms behind the observed variability, the changes in mean sea level pressure and precipitable water are quantified for different sub-periods. Also explored is the variability related to the Hadley cell width and strength over the region around SSA. Results show that the Hadley cell has shrunk and shifted towards the equator in winter over the area, which has caused an enhancement of the sinking motion over much of Argentina, Chile and Brazil, while likely increasing the baroclinicity (and associated precipitation) over Patagonia. In summer the strength of the subsidence decreased and this was associated with an increase of the low-level moisture advection, favoring more rainfall. The observational evidence presented here suggests that the zonal asymmetry in the change of the Hadley cell position over SSA could be linked to the presence of the Andes Cordillera.","palabras_clave":"precipitation|trends|long term|hadley cell"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5721,"idioma_id":5,"titulo":"Metodología para la clasificación y diagnóstico de Cadenas de Suministro","resumen":"La cadena de suministro (CS) bien planificada brinda resultados satisfactorios en las utilidades de la empresa. Sin embargo, muchas pymes de Argentina carecen de buenas prácticas en este aspecto.En este contexto, el presente estudio pretende contribuir al fortalecimiento de las pymes a través del diseño y aplicación de una metodología que permita clasificar las CS de las empresas, para posteriormente identificar  las estrategias adecuadas a aplicar en las mismas. Para complementar el estudio, se analiza además la alineación entre las estrategias empleadas fehacientemente por las empresas y  las recomendadas en la metodología propuesta.Los resultados evidencian que mayoritariamente las empresas poseen una ?CS rutinaria con bajo grado de influencia de la empresa focal?. En consecuencia las estrategias a aplicar, entre otras, son: productos estandarizados, precios bajos, calidad consistente, bajo perfil y capacidad de respuesta estándar. Asimismo, el 62% reconoce aplicar estrategias que se condicen con las recomendadas en la metodología.","palabras_clave":"cadena de suministro|estrategias|planificación|pymes"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5724,"idioma_id":4,"titulo":"Novel carvedilol paediatric nanomicelle formulation: in-vitro characterization and in-vivo evaluation","resumen":"Objectives Carvedilol (CAR) is a poorly water-soluble beta-blocker. Its encapsu-lation within nanomicelles (NMs) could improve drug solubility and its oralbioavailability, allowing the development of a paediatric liquid CAR formulationwith commercially available copolymers: D-a-tocopheryl polyethylene glycol1000 succinate (TPGS) and poly(vinyl caprolactam)-poly(vinyl acetate)-poly(ethylene glycol) (Soluplus).Methods Drug-loaded NMs were prepared by copolymer and CAR dispersion indistilled water. Micellar size and morphology were characterized by dynamic lightscattering and transmission electron microscopy, respectively. In-vitro drug per-meation studies were evaluated by conventional gut sac method. In-vivo CARoral bioavailability from NMs dispersions and drug control solution was evalu-ated in Wistar rats.Key findings Carvedilol apparent aqueous solubility was increased (up to 60.4-folds) after its encapsulation within NMs. The micellar size was ranged between10.9 and 81.9 nm with a monomodal size distribution. There was a significantenhancement of CAR relative oral bioavailability for both copolymers vs amicelle-free drug solution (P < 0.05). This improvement was higher for TPGS-based micelles (4.95-fold) in accordance with the in-vitro CAR permeationresults.Conclusions The present investigation demonstrates the development of highlyconcentrated CAR liquid micellar formulation. The improvement on drug oralbioavailability contributes to the potential of this NMs formulation to enhanceCAR paediatric treatment.","palabras_clave":"carvedilol"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5732,"idioma_id":4,"titulo":"POTENTIAL PROTECTIVE ROLE OF NITRIC OXIDE AND HSP70 LINKED TO FUNCTIONAL FOODS IN THE ATHEROSCLEROSIS","resumen":"Atherosclerosis, one of the main pathologic entities considered epidemic and a worldwide public health problem, is currently under constant review as regards its basic determining mechanisms and therapeutic possibilities. In this regard, all patients afflicted with the disease exhibit mitochondrial dysfunction, oxidative stress and inflammation. Interestingly, nitric oxide -a known vasoactive messenger gas- has been closely related to the inflammatory, oxidative and mitochondrial dysfunctional process that characterizes atherosclerosis. In addition, it has recently been demonstrated that alterations in the bioavailability of nitric oxide would induce the expression of heat shock proteins. This agrees with the use of functional foods as a strategy to prevent both vascular aging and the development of atherosclerosis. Finally, a greater knowledge regarding the mechanisms implied in the development of atherosclerosis will enable proposing new and possible hygiene, health and therapeutic interventions.","palabras_clave":"ATHEROSCLEROSIS|FUNCTIONA LFOOD|HEAT SHOCK PROTEIN|NITRIC OXIDE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5790,"idioma_id":4,"titulo":"Optimization of Microwave Pretreatment Variables for Canola Oil Extraction","resumen":"The influence of microwave pretreatment on the oil yield (solvent extraction) and oil quality of canola was studied. Response surface methodology was used to analyze the variables of microwave pretreatment, working with two microwave powers 80 and 100% (457 and 607 W, respectively, referred absorbed power of 1 Lof water). The independent variables were initial moisture content (5-10% dry basis) and pretreatment time (10-350 s), considering five levels. Second-order polynomial equations were used for oil yield, and first-order polynomial for final moisture content. The response models obtained were validated with independent experiments. Under optimal pretreatment conditions, no significant differences were detected in acidity, fatty acid profile and tocopherol content between the unpretreated and pretreated samples. However, significant differences were observed for peroxide index.","palabras_clave":"Canola Seeds|Microwave|Oil extraction"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5831,"idioma_id":4,"titulo":"Ruddy-headed Goose Chloephaga rubidiceps: former plague and present protected species on the edge of extinction","resumen":"The Ruddy-headed Goose has two separate and genetically distinct populations, one sedentary that inhabits the Malvinas\/Falklands Islands and another migratory which inhabits continental southern South America. New information suggests that this population should be considered as different evolutionary significant units. The latter population breeds in Austral Patagonia (Argentina and Chile) and overwinters in Central Argentina. It was a very common species in Austral Magellanic steppe grasslands before 1931, when it was declared an ?agriculture pest? by the Argentinian government, together with other sheldgeese species. Since then, the continental Ruddy-headed Goose population has declined becoming one of the scarcest species in Austral Magellanic steppe. Nowadays, its population is categorized as critically endangered in Argentina and endangered in Chile. We present data of six road censuses conducted in the breeding areas of Santa Cruz and Tierra del Fuego provinces, Argentina, during 2013-2014 and 2014-2015 (>4600 km, 70 days) and review population trends of the Ruddy-headed Goose since early 1900s. We counted a maximum of 19 individuals in Santa Cruz and 49 in Tierra del Fuego throughout the breeding season. Literature reviewed indicates that during the last 40 years the size of continental population of Ruddy-headed Goose has been less than 800 individuals, approximately 10% of the estimated population in 1900s. This decline matches with the period following the application of control techniques and the introduction of exotic predator species in the breeding grounds of Tierra del Fuego. We review and discuss formerly proposed conservation actions that may have a positive and rapid effect on sheldgeese numbers recovery. We suggest that the continental population of Ruddy-headed Goose should be precautionary treated as a CR group until genetic studies determine whether we are in the presence of a new ?critically endangered? species.","palabras_clave":"Chloephaga rubidiceps|conservation|Austral Patagonia|invasive predators"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5885,"idioma_id":4,"titulo":"Hepatitis E virus infection in patients on dialysis and in solid organ transplant recipients in Argentina: exploring associated risk factors","resumen":"Infection with hepatitis E virus (HEV) leads to acute hepatitis infection in immunocompetent hosts. HEV genotype 3 can present with high frequency and lead to chronic infection in individuals with a compromised immune system. The risk factors related to increased seroprevalence or chronicity in this population are not entirely understood. Moreover, most studies addressing risk factors for HEV in non-endemic areas come from developed areas such as North America and Europe. In this study we evaluated seroprevalence, chronicity and risk factors for HEV in 120 transplant recipients and 88 patients on dialysis in Argentina. We found a significantly higher seroprevalence of HEV IgG in those undergoing dialysis compared with healthy controls (10.2% and 4.3% respectively, p = 0.03). No difference in HEV seroprevalence was observed between healthy controls and transplant recipients (5.8%). We found no association between previously identified risk factors for HEV, such as pork consumption or use of tacrolimus, and HEV seroprevalence. In univariate and multivariate analyses, consumption of fish was associated with higher seroprevalence of HEV (OR = 9.33; 95% CI: 2.07?42.2; p = 0.04). None of the samples showed HEV RNA amplification, indicating that chronicity does not seem to be an issue in these cohorts. Our results show increased seroprevalence of HEV in individuals undergoing dialysis but not in transplant recipients. We also found that fish consumption can be a potential risk factor for acquiring HEV.","palabras_clave":"HEV|PREVALENCE |IMMUNOSUPPRESSED SUBJECTS|HEMODIALYSIS|RISK FACTORS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5891,"idioma_id":4,"titulo":"RELATIVE BIOAVAILABILITY OF COENZYME Q10 FORMULATION FOR PEDIATRIC INDIVIDUALIZED THERAPY","resumen":"OBJECTIVES:Conduct a preliminary comparison of the bioavailability between two formulations: commercial grade coenzyme Q10 (CoQ10) powder (solid formulation) and a new oil-in-water liquid emulsion and their effect on other antioxidants.METHODS:Six healthy individuals participated in a randomized, crossover, open, consecutive design, with a 2-week washout period. Pharmacokinetic parameters were assessed after a single and multiple intakes of 250 mg CoQ10 given daily for 1 week.KEY FINDINGS:The differences in the pharmacokinetic parameters of maximum plasma concentration, area under the curve between 0-360 and 0-4 h, elimination half-life were statistically significant with a relative bioavailability of 489% increase over solid CoQ10 formulation. A multiple dose supplementation increased plasma CoQ10 levels in both formulations, liquid emulsion performing better (2.4- vs 3.9-fold for solid and liquid formulation, respectively) without modifications on other antioxidants. Furthermore, the plasma CoQ10 at 7th day was statistically different between formulations (P < 0.05).CONCLUSIONS:The results obtained showed that liquid emulsion improves the bioavailability of CoQ10 respect to solid form which not only facilitates the individualized administration for the child but in turn could increase the therapeutic efficacy, which should be confirmed by further studies.","palabras_clave":"COENZYME Q10|RELATIVE BIOAVAILABILITY|PEDIATRC|PHARMACOKINETIC"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5920,"idioma_id":4,"titulo":"Vacuolar deposition of recombinant proteins in plant vegetative organs as a strategy to increase yields","resumen":"Delivery of recombinant proteins to vegetative tissue vacuoles was considered inconvenient since this compartment was expected to be hydrolytic; nevertheless there is growing evidence that certain foreign proteins accumulate at high yields in vacuoles. For example avidin, cellulolytic enzymes, endolysin, and transglutaminases were produced at high yields when were sorted to leaf central vacuole avoiding the detrimental effect of these proteins on plant growth. Also, several secretory mammalian proteins such as collagen, &#945;1-proteinase inhibitor, complement-5a, interleukin-6 and immunoglobulins accumulated at higher yields in leaf vacuoles than in the apoplast or cytosol. To reach this final destination, fusions to sequence specific vacuolar sorting signals (ssVSS) typical of proteases or proteinase inhibitors and\/or Ct-VSS representative of storage proteins or plant lectins were used and both types of motifs were capable to increase accumulation. Importantly, the type of VSSs or position, either the N or C-terminus, did not alter protein stability, levels or pos-translational modifications. Vacuolar sorted glycoproteins had different type of oligosaccharides indicating that foreign proteins reached the vacuole by 2 different pathways: direct transport from the ER, bypassing the Golgi (high mannose oligosaccharides decorated proteins) or trafficking through the Golgi (Complex oligosaccharide containing proteins). In addition, some glycoproteins lacked of paucimannosidic oligosaccharides suggesting that vacuolar trimming of glycans did not occur. Enhanced accumulation of foreign proteins fused to VSS occurred in several plant species such as tobacco, Nicotiana benthamiana, sugarcane, tomato and in carrot and the obtained results were influenced by plant physiological state. Ten different foreign proteins fused to vacuolar sorting accumulated at higher levels than their apoplastic or cytosolic counterparts. For proteins with cytotoxic effects vacuolar sorted forms yields were superior than ER retained variants, but for other proteins the results were the opposite an there were also examples of similar levels for ER and vacuolar variants. In conclusion vacuolar sorting in vegetative tissues is a satisfactory strategy to enhance protein yields that can be used in several plant species.","palabras_clave":"plant molecular farming|foreign proteins|vegetative tissue|vacuolar sorting signals"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5955,"idioma_id":4,"titulo":"Reproductive aspects of Notothenia rossii and N. coriiceps (Perciformes, Nototheniidae) at Potter Cove, 25 de Mayo (King George) Island during austral summer","resumen":"Enviado a Polar Biology el 26-6-2015 y aceptado con cambios 16-12-15.Several fish species of the suborder Notothenioidei (Perciformes) predominate in the Antarctic Convergence Zone nevertheless, reproductive studies are scarce due to difficulties on regular sampling. This study takes the research area of reproductive biology of nothotenioids to a new level by providing, for the first time, data on sex hormone and vitellogenin detection in the blood of females of Notothenia rossii and N. coriiceps, and correlates this data with morphological maturity indices as well as ovarian histology. Fish were captured during the Antarctic summer at Potter Cove, 25 de Mayo (King George) Island, and blood and ovary were collected. Histological analysis revealed that females of both fish possess group synchronous ovarian development with two distinct clutches of oocytes: a more advanced batch of vitellogenic oocytes ready for spawning, and a second batch of previtellogenic oocytes for the next spawning event. Since liver vitellogenin synthesis is stimulated by estradiol produced by the ovaries, gonadal development, estradiol levels, and vitellogenin showed that both species were at a more advanced stage of maturation in March than in January. On the other hand and irrespectively of the month, gonadosomatic index and plasma estradiol levels of N. coriiceps were higher than those of N. rossii. Furthermore, females of N. coriiceps showed an advanced stage of vitellogenesis or were ready for spawn, contrary to results of previous studies. Our results indicate the successful use of gonadal morphology, estradiol and vitellogenin detection for the estimation of sexual maturity stage of female adults.","palabras_clave":"Notothenia|ovario sincrono por grupo|vitelogenina"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5958,"idioma_id":5,"titulo":"Estudios de arqueología distribucional en Monte Loayza (costa norte de Santa Cruz, Patagonia)","resumen":"En este trabajo se presentan los primeros resultados de los estudios distribucionales realizados en el sector Monte Loayza en la costa norte de Santa Cruz. Estos se plantearon con el objetivo de conocer las características estructurales del registro arqueológico superficial de este sector, del cual se contaba con escasos antecedentes. El sector Monte Loayza reúne una serie de características particulares que permiten contrastar hipótesis previas en relación con el uso de los distintos tipos de costas, los recursos allí disponibles y las formas de ocupación de los espacios costeros e interiores formuladas en el proyecto marco. De esta forma, los estudios distribucionales permitieron registrar que este sector presenta, en términos generales, densidades bajas a medias, menores a las observadas, en promedio, en otros sectores de la costa norte de Santa Cruz. Sin embargo, se observa una mayor intensidad de uso, interpretada como un aprovechamiento residencial de algunos tramos de la costa y los cañadones; mientras que otro tramo de costa -con alta disponibilidad de distintos tipos de recursos- presenta un registro artefactual muy escaso, lo cual probablemente se relacione con su difícil accesibilidad.","palabras_clave":"ARQUEOLOGÍA DISTRIBUCIONAL|MONTE LOAYZA|ARTEFACTOS LÍTICOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5972,"idioma_id":4,"titulo":"Ground beetles (Coleoptera: Carabidae) inhabiting anthropogenic habitats in the Lower Delta of the Paraná River, Argentina: geographic distribution and ecological characteristics","resumen":"The primary aims of this paper were to provide the first inventory of carabid beetles collected in five different anthropogenic habitat types of the Lower Delta of the Paraná River, to describe their main ecological characteristics, and to provide information on their distribution range in ecoregions, subregions and ecosystem complexes of Argentina and across the Neotropical region. Species were grouped according to six classes of distributions in relation to their presence in the Delta of the Paraná River. In addition, rarefaction curves were built in order to compare the seasonal species richness. We collected 1486 individuals belonging to 48 species. The southernmost distribution limit of 50% of the species is located south of the Delta region. Moreover, 21% of the species are confined to the Delta and Islands of the Parana and Uruguay Rivers ecoregion and to localities within the neighboring ecoregions of Espinal and Pampa. Most (63%) of the species were zoophagous and 25% were either omnivorous or seed eaters; 52% were hydrophilous, 44% mesophilous and one was xerophilous. The high number of species found in this ecoregion emphasizing its importance as a biodiversity hotspot of South American carabids. Human activities have led to changes in the landscape of the Delta Islands which could favor the establishment of mesophilous and xerophilous species from other ecoregions. Seasonal carabid richness is higher in the warm seasons (spring and summer) compared with the cold seasons (autumn and winter). Although, the highest absolute richness was found in the most anthropized habitat types, secondary forests had exclusive species, showing the importance of preserving the ecological mosaic of the landscape.","palabras_clave":"WETLANDS|HÁBITAT USE|ARGENTINIAN ECOREGIONS|CARABIDAE ASSEMBLAGE|AFFORESTATION HABITAT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5987,"idioma_id":5,"titulo":"Jóvenes y universidad. El PROGRESAR y la democratización del nivel superior","resumen":"El artículo analiza la ampliación del derecho a la educación que en América Latina ha estado asociada a políticas de transferencia condicionada de ingresos. Nos centraremos en el nivel universitario, a partir de la implementación del Programa de Respaldo a Estudiantes de Argentina (PRO.GRE.SAR). Los hallazgos sugieren que, a diferencia de las políticas precedentes, el PRO.GRE.SAR flexibiliza los criterios meritocráticos que históricamente fortalecieron la lógica selectiva de la escolaridad al tiempo que reconoce a los grupos sociales más desaventajados como legítimos estudiantes universitarios. Asimismo, establece mecanismos de mayor integralidad en la norma mediante el acompañamiento a las trayectorias que ponen de relieve la intención de un abordaje holístico de la problemática juvenil. No obstante los avances de la medida en términos de ampliación de derechos, la democratización efectiva del nivel se dirime en el plano de la institucionalidad y del trabajo pedagógico tendiente a superar la tradición selectiva del nivel. Dada la autonomía universitaria, la democratización de la educación superior depende en mayor medida que en los niveles obligatorios, de los modos de apropiación institucional de la política en función de las trayectorias particulares de las universidades nacionales y de las reglas y recursos disponibles para alterar los modos de reproducción de los privilegios.","palabras_clave":"PROGRESAR|JOVENES|UNIVERSIDAD|DEMOCRATIZACION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":5998,"idioma_id":4,"titulo":"Heterochromatin and rDNA patterns in Solanum species of the Morelloid and Dulcamaroid clades (Solanaceae)","resumen":"The heterochromatin distribution and the position of 18-5.8-26S and 5S rDNA loci were determined in 13 species of Solanum of the Morelloid and Dulcamaroid clades. The CMA\/DAPI staining and FISH was employed. Two types of constitutive heterochromatin were determined: CMA+\/DAPI- associated to NOR and CMA+\/DAPI- distributed as terminal bands. In the Morelloid clade, CMA+\/DAPI- bands were found in five species, while in the Dulcamaroid clade, only S. angustifidum presented this feature. In the Morelloid clade, from two to four 18-5.8-26S rDNA loci occupied terminal positions, and 2 rDNA 5S loci were found with variable positions (terminal, intercalary and centromeric). In the Dulcamaroid clade, two terminal 18-5.8-26S rDNA loci were detected, with the exception of S. salicifolium, which possessed four such loci and two to four 5S rDNA loci. Solanum crispum is the only species possessing the 5S in synteny with 18-5.8-26S rDNA loci. Karyotype features, chromosome banding pattern as well as the location of ribosomal genes varied among the species, reflecting the chromosome differentiation and evolutionary divergence. The findings obtained contributed to the development of tools that can be used for establishing chromosomic homeologies among species and hence to clarify their taxonomic relationships.","palabras_clave":"bandeo fluorescente|FISH|cariotipo|evolucion"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6004,"idioma_id":4,"titulo":"Alternating temperature combined with darkness resets base temperature for germination ( T b ) in photoblastic seeds of Lippia and Aloysia (Verbenaceae)","resumen":"Thermal time models for seed germination assume a continuum of rate responses inthe sub-optimal temperature range. Generally, the models describe germination performance in non-dormant seeds at constant temperatures, yet alternating temperature (AT) is a feature of many natural environments. We studied the possible interacting effects of AT on germination progress in photoblastic seeds of three aromatic?medicinal Verbenaceae species in the genera Lippia and Aloysia. For Lippia turbinata f. turbinata and L. turbinata f. magnifolia seed, germination only occurred in light conditions, while for L. integrifolia and Aloysia citriodora it was significantly higher in the light than in darkness. Although relative light germination (RLG) was not different between constant and AT in the sub-optimal range, AT raised the base temperature for germination progress (Tb) from ca. 3?6 °C in constant temperature to 7?12 °C in AT. Among the species, thermal time for 50% seed germination [hT(50)] was 55?100 °Cd at constant temperature. Although AT resulted in slight modificationsto hT(50), the germination rate at comparable average temperatures in thesub-optimal range was slower than under constant temperatures. For all species, the proportion of germinated seeds was similar for constant and AT. Our results suggest that an interaction between cool temperature and darkness during AT treatment limits the temperature range permissive for germination in these positively photoblastic seed, reflecting both close adaptation to the natural ecology and niche requirements of the species.","palabras_clave":"Arid environment|cardinal temperatures|germination ecology|phenotypic plasticity"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6038,"idioma_id":4,"titulo":"Prediction of data visibility in two-dimensional scatterplots","resumen":"The result of a visualization process depends on the user?s decisions along it. With the intention of accelerating this process and guaranteeing an appropriate visualization of the data, we are looking to semi-automatize the process to help the users with the decision-making along it. To contribute to this semi-automation, it is useful to have metrics that characterize different important aspects of the visualization techniques, such as data representation visibility. Besides, scatterplots are a widely used technique to visualize scalar datasets. In this context, this work presents a metric that evaluates data representation visibility considering glyph visibility in scatterplots. We defined a metric that estimates the proportion of glyphs that will be visible regardless of the drawing order, and it depends on the number of items in the dataset, the size of the window, and the size of the glyphs that will represent the data. To define and approximate the metric, we experimented with several random datasets for which both dimensions followed a normal distribution. This metric constitutes an alternative to characterize scatterplots and collaborates in the semi-automation of the user?s decisions along the visualization process.","palabras_clave":"INFORMATION VISUALIZATION|VISUALIZATION TECHNIQUE|SCATTERPLOTS|VISUAL SCALABILITY METRIC|VISIBILITY METRIC"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6050,"idioma_id":4,"titulo":"1.\tHistamine H2 receptor in blood cells: a suitable target for the treatment of acute myeloid leukemia","resumen":"Acute myeloid leukemia (AML) consists in a cancer of early hematopoietic cells arising in the bone marrow, most often of those cells that would turn into white blood cells (except lymphocytes). Chemotherapy is the treatment of choice for AML but one of the major complications is that current drugs are highly toxic and poorly tolerated. In general, treatment for AML consists of induction chemotherapy and post-remission therapy. If no further post-remission is given, almost all patients will eventually relapse. Histamine, acting at histamine type-2 (H2) receptors on phagocytes and AML blast cells, helps prevent the production and release of oxygen-free radicals, thereby protecting NK and cytotoxic T cells. This protection allows immune-stimulating agents, such as interleukin-2 (IL-2), to activate cytotoxic cells more effectively, enhancing the killing of tumor cells. Based on this mechanism, post-remission therapy with histamine and IL-2 was found to significantly prevent relapse of AML. Alternatively, another potentially less toxic approach to treat AML employs drugs to induce differentiation of malignant cells. It is based on the assumption that many neoplastic cell types exhibit reversible defects in differentiation, which upon appropriate treatment results in tumor reprogramming and the induction of terminal differentiation. There are promissory results showing that an elevated and sustained signaling through H2 receptors is able to differentiate leukemia-derived cell lines, opening the door for the use of H2 agonists for specific differentiation therapies. In both situations, histamine acting through H2 receptors constitutes an eligible treatment to induce leukemic cell differentiation, improving combined therapies.","palabras_clave":"LEUKEMIA|HISTAMINE|H2 RECEPTOR"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6052,"idioma_id":4,"titulo":"Lectin histochemistry for detecting cadmium-induced changes in the glycosylation pattern of rat placenta","resumen":"Cadmium (Cd) is an industrial and environmental pollutant that produces toxic effects on gametogenesis, pre- and post-implantation embryos, and the placenta. Because the effects of acute Cd intoxication on the placenta are not well understood, we investigated changes in its glycosylated components in Cd treated dams at days 4, 7, 10 and 15 of gestation using lectin histochemistry. CdCl2 was administered to pregnant rats; control animals received sterile normalsaline. Placentas were processed for DBA, Con A, SBA, PNA, UEA-I, RCA-I and WGA lectin histochemistry to evaluate changes in the carbohydrate pattern of the placenta that might modify cell interactions and contribute to embryonic alterations. Lectin binding was analyzed in the yolk sac; trophoblast giant cells; trophoblast I, II and III; spongiotrophoblast cells and endovasculartrophoblast cells in the chorioallantoic placenta. Our lectin binding patterns showed that Cd caused alteration of SBA and DBA labeling of trophoblast-derived cells, which suggested  increased expressions of &#945; and &#946; GalNAc. Cd also caused decreased UEA-1 binding affinity, which indicated fewer &#945;-L-Fuc residues in placentas of Cd treated dams. The nonreactivity in trophoblast I of the control placentas incubated with Con-A contrasted with the labeling in placentas of experimental dams, which indicated increased expression of terminal &#945;-D-Man,and &#945;-D-Glc residues. We found that Cd altered the reactivity of placenta to several lectins, which indicated modification of the glycotype presented by the fetal component of the placenta.We report that Cd exerts a deleterious effect on the glycosylation pattern of the placenta.","palabras_clave":"CADMIO|CARBOHYDRATES MOIETIES|GLYCOPROTEINS|LECTINHISTOCHEMISTRY|PLACENTA|RAT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6062,"idioma_id":4,"titulo":"Gas and crystal structures of CCl2FSCN","resumen":"Dichlorofluoromethyl thiocyanate, CCl2FSCN, was structurally studied in the solid and in the gas phase by means of single-crystal X-ray (XRD) and gas electron diffraction (GED), respectively. In the gas phase the title molecule adopts two stable conformers, described by the FC&ndash;SC dihedral angle. The gauche-conformer (FC bond with respect to the SC bond) is more stable than the anti-conformer. In this work we present the first experimental evidence for the existence of the anti-CF2ClSCN form. In the solid state only the most stable gauche-conformer was found. Intermolecular interactions were detected in the crystal structure and analyzed. A structural comparison of the results with those of related species as CCl2FSCN, CCl3SCN and CH2ClSCN is presented.","palabras_clave":"GAS ELECTRON DIFFRACTION|X-RAY STRUCTURE|THIOCYANATE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6070,"idioma_id":4,"titulo":"Association between grain yield, grain quality and morpho-physiological traits along ten cycles of recurrent selection in bread wheat (Triticum aestivum L.)","resumen":"The objective of the present investigation was to examine the relationships between agronomical behavior and grain quality along ten cycles of a recurrent selection program performed under rainfed condition. Twenty four lines, four for each one of the 0, 2, 4, 6, 8 and 10 cycles of recurrent selection, were evaluated for two consecutive years (2011 and 2012). The experimental lines were evaluated under conventional (CT) and no tillage (NT) systems. Grain yield and grain weight were determined and harvest index and grain number estimated. Flour protein content, sodium dodecyl sulphate sedimentation (IS-SDS) and lactic acid SRC (LASRC) were considered as end-use quality predictive tests. The Spearman correlation coefficient was used to measure the relationships among yield, its components and grain quality parameters. Within the context of CT, flour protein content was negatively associated with all the agronomic variables. The IS-SDS has a negative association with the grain weight; meanwhile, LASRC associated positively with all the agronomic variables. When wheat was grown in NT, the relationship between IS-SDS and harvest index, like LASRC with all agronomic traits, was positive. Confining the discussion to the CT results, after tencycles of recurrent selection the highest grain yield achieved was accompanied by a decrease in protein percentage. However, the decrease in the percentage of protein in more advanced selection cycles was offset by an improvement of its quality.","palabras_clave":"Recurrent selection|reduced tillage|bread quality"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6088,"idioma_id":4,"titulo":"Trophic interactions and food web structure of a subantarctic marine food web in the Beagle Channel: Bahía Lapataia, Argentina","resumen":"t Basic ecological knowledge regarding the importance of different sources of primary production and how it is transferred among consumer species is required to properly manage and conserve subpolar ecosystems that are particularly vulnerable to environmental changes. We used carbon (d13C) and nitrogen (d15N) stable isotope analysis to establish a baseline of species interactions and food web structure for the nearshore marine community in Bahia Lapataia, Argentina, an ecosystem that faces many threats, including a recent invasion of exotic chinook sal- mon. Primary producers and other organic sources (e.g., particulate organic matter) available to the food web were isotopically distinct and had a wide range in d13C (-31.3 to -5.3 %) and d15N (-0.5 to 13.1 %) values. Consumers also showed a wide range of isotope values with mean d13C and d15N values ranging from -20.8 to -12.3 % and from 10.5 to 19.6 %, respectively. A cluster analysis of these isotope data correctly identified functional groups and expected interactions among species based on independent information. Using Bayesian isotope mixing models, we estimated that the proportional contribution of benthic production, in particular through grazing and the con- sumption of detritus, was a more important source of energy for primary and secondary consumers than pelagic production. Using stable isotope analysis to continually monitor species interactions and food web structure may prove to be a valuable research and management tool for assessing ecological consequences of different threats in this and other subpolar ecosystems.","palabras_clave":"FOOD WEB|COMUNITY STRUCTURE|TROPHIC LEVEL|BIOLOGICAL BASELINE DATA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6101,"idioma_id":4,"titulo":"New small-size peptides modulators of the exosite of BACE1 obtained from a structure-based design","resumen":"We report here two new small-size peptides acting as modulators of the BACE1 exosite. Ac-YPYFDPL-NH2 and Ac-YPYDIPL-NH2 displayed a moderated but significant inhibitory effect on BACE1. These peptides were obtained from a molecular modeling study. By combining MD simulations with ab initio and DFT calculations, a simple and generally applicable procedure to evaluate the binding energies of small-size peptides interacting with the exosite of the BACE1 is reported here. The structural aspects obtained for the different complexes were analyzed providing a clear picture about the binding interactions of these peptides. These interactions have been investigated within the framework of the density functional theory and the quantum theory of atoms in molecules (QTAIM) using a reduced model. Although the approach used here was traditionally applied to the study of non covalent interactions in small molecules complexes in gas phase, we show through in this work that this methodology is also a very powerful tool for the study of biomolecular complexes, providing a very detailed description of the binding event of peptides modulators at the exosite of BACE1. ","palabras_clave":"ALZHEIMER|BACE1"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6108,"idioma_id":4,"titulo":"Metal Bioleaching from Anaerobic Sediments from Reconquista river Basin (Argentina) as potential Remediation Strategy","resumen":"Anaerobic sediments of urban watercourses are subjected to industrial pollution and frequently tend to accumulate heavy metals. The biocatalyzed oxidation and reduction of sulphur compounds that occur within the sediment are key reactions that determine mobility of metals such as occurs in mine acidic drainage reactions. The aim of this work was to study the application of this processes using heap leaching technology for the remediation of anaerobic contaminated sediments from Reconquista River basin. The bioleaching potentiality for remediation was demonstrated through batch tests in shake flasks with different pulp densities of anaerobic sediment containing 338 mg Kg-1 of Zn and 117 mg Kg-1 of Cu. Subsequently, bioleaching heap systems were compiled into columns of 12 cm high and 6 cm diameter, fitted with perlite to improve drainage. In order to assess the effect of elementary sulphur over the mobility of metals from the bioheap to the aqueous solution, increasing concentrations of elementary sulphur (1 %, 2 %, 5 % w\/w) were added. After 3 months of acidification generated by periodic watering, the extraction of 70 % of the initial Zn and 43 % of the initial Cu was achieved.Polluted sediments from waterways as Reconquista River should not be indiscriminately manipulated if acid drainage is possible. Remediation by a simple and economically viable strategy like heap leaching is feasible.","palabras_clave":"ANAEROBIC POLLUTED SEDIMENTS|BIOHEAPLEACHING|HEAVY METALS |REMEDIATION STRATEGY|SULPHUR-OXIDIZING BACTERIA |RECONQUISTA BASIN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6158,"idioma_id":4,"titulo":"Genome-wide association mapping of genetic factors controlling Septoria tritici blotch resistance and their associations with plant height and heading date in winter wheat","resumen":"Septoria tritici blotch (STB), caused by the ascomycete fungus Mycosphaerella graminicola, is one of the most devastating foliar wheat diseases in worldwide. Host resistance is the most effective strategy for management of the disease. A factor that complicates the determination of resistance is its reported interaction with heading date (Hd) and plant height (Ph). In this study, we reported findings from a genome-wide association mapping (GWAM) of resistance to STB in a collection of 96 winter wheat accessions. The collection was evaluated under conditions of artificial infection for seedling and adult plant STB resistance in field trials. Marker-trait associations (MTAs) were detected using both general and mixed linear model. STB disease severities presented significant phenotypic variation. In total, 119 MTAs associated with STB resistance were detected. The chromosomal location of some of them coincided with those of known Stb genes or quantitative trait loci; while others were detected in genomic regions where not known genes have been reported. The field experiment only showed evidence of genetic association between STB resistance and Hd. However, it was attributed to a few genotypes. This was corroborated at molecular level, where a total of 11 genomic regions associated to STB resistance were located in the similar position as Hd MTAs. After validation in relevant genetic backgrounds, novel genomic regions associated to STB resistance found here, could be useful in wheat breeding aimed at controlling STB. Finally, quantitative studies of STB resistance must take into account the effect of Hd and Ph on the levels of the disease.","palabras_clave":"genetic resistance|Zymoseptoria tritici|association mapping"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6183,"idioma_id":4,"titulo":"P35 and P22 Toxoplasma gondii antigens abbreviate regions to diagnose acquired toxoplasmosis during pregnancy: towards single-sample assays","resumen":"Background: P35 and P22 Toxoplasma gondii proteins are recognized by specific IgG at the early infection stage, making them ideal for acute toxoplasmosis pregnancy control. Both proteins have been studied to discriminate between acute and chronic toxoplasmosis. However, results were hardly comparable because different protein obtainment procedures led to different antigens, the reference panels used were not optimally typified, and avidity tests were either not performed or narrowly examined. Methods: We bioinformatically predicted P35 and P22 regions with the highest density of epitopes, and expressed them in pET32\/BL21DE3 alternative expression system, obtaining the soluble proteins rP35a and rP22a. We assessed their diagnostic performance using pregnant woman serum samples typified as: not infected, NI (IgG-, IgM-), typical-chronic, TC (IgM-, IgG+), presumably acute, A (IgG+, IgM+, low-avidity IgG), and recently chronic, RC (IgG+, IgM+, high-avidity IgG). Results: rP35a performed better than rP22a to differentiate A from RC, the areas under the curve (AUC) being 0.911 and 0.818, respectively. They, however, performed similarly to differentiate A from TC + RC (AUC: 0.915 and 0.907, respectively). rP35a and rP22a evaluation by avidity ELISA to discriminate A from RC rendered AUC values of 0.974 and 0.921, respectively. The indirect ELISA and avidity ELISA results analyzed in tandem were consistent with those obtained using commercial kits. Conclusions: rP35a and rP22a features suggest that, with complementary use, they could replace parasite lysate for toxoplasmosis infection screening and for acute toxoplasmosis diagnosis. Our proposal should be validated by a longitudinal study and may lead to a reliable toxoplasmosis pregnancy control, performing tests in only one serum sample.","palabras_clave":"Acute toxoplasmosis diagnosis|Toxoplasma gondii|P35&P22 recombinant proteins|Immunochemical reagents|Pregnancy control|Epitope prediction"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6187,"idioma_id":4,"titulo":"Poverty Impacts of Changes in the International Prices of Agricultural Commodities: Recent Evidence for Argentina (An Ex-Ante Analysis)","resumen":"Argentina has benefited greatly from the increase in prices of agricultural commodities. With a large share of its population with low and medium-low incomes; however, a sizable part of households is likely to be adversely affected by the accompanying rise in the price of the consumption basket. An ex-ante analysis suggests that this is the case. Changes through a less obvious channel (that is, in factor incomes) are likely to be more beneficial to middle-income households. In general, all households experience losses, with poorer households being the most affected. When accounting for transfers financed through the collection of export taxes, poorer households benefit. In the absence of compensatory measures, increases in the prices of agricultural commodities could potentially have an important impact in terms of indigence and poverty.","palabras_clave":"Poverty|Commodities|Argentina"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6190,"idioma_id":4,"titulo":"Divergent cloacal gland photo-responsiveness in male Japanese quail exposed to short days and associated differences in social interactions and reproduction","resumen":"Quail under short d (SD) reduce their gonadal development, and consequently their cloacal gland (CG) size, aggressiveness, sexual behaviors, and reproductive performance. However, some quail appear nonresponsive to SD inhibition. When male quail were arbitrarily classified according to their CG involution during maximum photoinhibition (5 wk after SD exposure) as either nonresponsive (NR-SD) or responsive (R-SD), NR-SD quail showed intermediate CG volume between R-SD quail and the control quail kept on long d (C-LD). Herein, we evaluate whether NR-SD and R-SD male Japanese quail differ in their social interactions and reproductive performance while under SD; C-LD males were used as fully reproductive control. First, we assessed over 4 consecutive d, brief (5-min) home cage encounters between individually housed CLD, NR-SD, or R-SD males and an unfamiliar C-LD male visitor. To determine male reproductive capacity, the following wk, males received the visit (10-min) of a mature female over 3 consecutive days. C-LD, NRSD, and R-SD resident males showed higher aggressiveness than their photostimulated male visitors, respectively, in 100, 64, and 0% of the studied cases and were also able to, respectively, fertilize 100, 100, and 15% of their female visitors. Second, male-female encounters were again repeated 4 wk later to further assess reproductive performance and behavior. Naive C-LD, NR-SD, and R-SD males also were evaluated to assess potential consequences of the previous male-male interactions on the later performance. The number of males performing aggressive pecks towards females showed a C-LD>NR-SD>R-SD pattern. While mounts, CG contacts, and reproductive capacity showed a C-LD = NRSD> R-SD pattern, copulatory efficiency exhibited an NR-SD>C-LD = R-SD pattern. Sexual behaviors were not modulated by previous male-male brief social interactions. Findings suggest that NR-SD males are able to breed similarly to their C-LD counterparts, which could be considered an indicator of a reduced reproductive dependence on seasonal photoperiod cues. Differences in the expression of aggressions between NRSD and C-LD males may underlie the observed NR-SD improved copulatory efficiency when interacting with females.","palabras_clave":"Japanese quail|cloacal gland photoresponsiveness|aggressive behavior|reproductive behavior"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6205,"idioma_id":4,"titulo":"Role of small rodents in the seed dispersal process: Microcavia australis consuming Prosopis flexuosa fruits","resumen":"Understanding the functional role of animal species in seed dispersal is central to determining how biotic interactions could be affected by anthropogenic drivers. In the Monte Desert, mammals play different functional roles in Prosopis flexuosa seed dispersal, acting as opportunistic frugivores (endozoochorous mediumsized and large mammals) or seed hoarders (some small sigmodontine rodents). Our objective was assessing the functional role of Microcavia australis, a small hystricognathi rodent, in the fruit removal and seed deposition stages of P. flexuosa seed dispersal, compared to sympatric sigmodontine rodents. In situ, we quantified fruit removal by small rodents during non-fruiting and fruiting periods, and determined the distance seeds were transported, particularly by M. australis. In laboratory experiments, we analysed how M. australis stores seeds (through scatter- or larder-hoarding) and how many seeds are left in caches as living seeds, relative to previousdata on sigmodontine rodents. To conduct field studies, we established sampling stations under randomly chosen P. flexuosa trees at the ~ Nacu~nan Man and Biosphere Reserve. We analysed fruit removal by small rodents and seed dispersal distance by M. australis using camera traps focused on P. flexuosa fruits covered with wire screen, which only allowed entry of small animals. In laboratory trials, we provided animals with a known number of fruits and assessed seed conditions after removal. Small rodents removed 75.7% of fruit supplied during the non-fruiting period and 53.2% during the fruiting period. Microcavia australis and Graomys griseoflavus were the main fruit removers. Microcavia australis transported seeds to a mean distance of 462 cm and cached seeds mainly in scatter-hoards, similarly as Eligmodontia typus. All transported seeds were left in fruit segments or covered only by the endocarp, never as predated seeds. Microcavia australis disperses P. flexuosa seeds by carryingfruits away from a source to consume them and then by scatter-hoarding fruits and seeds.","palabras_clave":"LARDER-HOARDING|RODENT|SCATTER-HOARDING|SEED DISPERSAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6208,"idioma_id":4,"titulo":"Burden of cancer mortality and differences attributable to demographic aging and risk factors during 1986-2011 period in Argentina","resumen":"The world faces an aging population that implies a large number of people affected with chronic diseases. Argentina has reached an advanced stage of demographic transition and presents a comparatively high rate of cancer mortality within Latin America. The objectives of this study were to examine cancer mortality trends in the province of Córdoba, Argentina between 1986 and 2011, and to analyze the differences attributable to risk variations and demographic changes. Longitudinal series of age-standardized mortality rates for overall, breast and prostate cancers were modeled by Joinpoint regression to estimate the annual percent change. The Bashir & Estève method was used to split crude mortality rate variation into three components: mortality risk, population age structure and population size. A decreasing cancer age-standardized mortality rates trend was observed (1986-2011 annual percent change: -1.4, 95%CI: -1.6, -1.2 in men; -0.8, 95%CI: -1.0, -0.6 in women), with a significant shift in 1996. There were positive crude mortality rate net changes for overall female cancer, breast and prostate cancers, which were primarily attributable to demographic changes. Inversely, overall male cancer crude mortality rate showed a 9.15% decrease, mostly due to mortality risk. Despite favorable age-standardized mortality rates trends, the influence of population aging reinforces the challenge to control cancer in populations with an increasingly aged demographic structure.","palabras_clave":"CANCER|MORTALITY|AGEING|RISK FACTORS|TIME-SERIES|JOINPOINT REGRESSION|CÓRDOBA|ARGENTINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6229,"idioma_id":4,"titulo":"Reduction of nitrate by heterogeneous photocatalysis over pure and radiolytically modified TiO2 samples in the presence of formic acid","resumen":"Heterogeneousphotocatalytic reduction of nitrate (2 mM) in the presence of formic acid (FA, 10mM) using pure and modified TiO2 samples under UV-visibleirradiation was performed at pH 3, and the evolution of the intermediate andfinal products was analyzed. For this work, commercial samples (Evonik P25 and Cristal Global PC500 and PC10) were modified by g-radiolysis with two noble metal nanoparticles known to behave differently in NO3&#8722; transformation, Ag and Pd. P25 was modified with Ag (0.5 and 2% w\/w), while PC10 and PC500 were modified with Pd (1% w\/w). The order of the photocatalytic activity of the materials for NO3&#8722; transformation was 2 Ag-P25 &gt; PC500&gt; 0.5 Ag-P25 &#8776; P25 &gt;&gt; 1 Pd-PC500 &gt; PC10 &gt; 1 Pd-PC10. Nitrite formation was observed in all cases but at low amounts, and its concentration was negligible (&#8804; 1 µM) after complete NO3&#8722; reduction. Ammonium was found as final product and remained in considerable amounts at the end of the irradiation. The nitrogen balance accounted for a large amount of non-identified nitrogen products formed during the photocatalytic reaction, probably N2 orNO; this amount was higher for the P25 and PC500 pure samples. The efficiency on the use of FA as donor was evaluated and PC500 was found to be the most efficient in this sense. A mechanism is proposed to clarify the still not well understood process of TiO2 heterogeneous photocatalytic transformation of nitrate, based on literature data and detected products.","palabras_clave":"nitrate|TiO2|formic acid|radiolytically modified TiO2|nitrite|ammonium"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6240,"idioma_id":4,"titulo":"Interpolation Based Controller for Trajectory Tracking in Mobile Robots","resumen":"In this work, a novel algorithm for trajectory tracking in mobile robotsis presented. For the purpose of tracking trajectory, a methodology based on theinterpolation of trigonometric functions of the wheeled mobile robot kinematics isproposed. In addition, the convergence of the interpolation-based control systemsis analysed. Furthermore, the optimal controller parameters are selected throughMonte Carlo Experiments (MCE) in order to minimize a cost index. The MCE isable to nd, the best set of gains that minimizes the tracking error. Experimentalresults over a mobile robot Pionner 3AT are conclusive and satisfactory. In addi-tion, a comparative study of control performance is carried out against anothercontrollers.","palabras_clave":"Trajectory tracking|Mobile robot|Control|Multivariable"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6285,"idioma_id":4,"titulo":"VULNERABILITY OF C6 ASTROCYTOMA CELLS AFTER SINGLE-COMPOUND AND JOINT EXPOSURE TO TYPE I AND TYPE II PYRETHROID INSECTICIDES","resumen":"A primary mode-of-action of all pyrethroid insecticides (PYRs) is the disruption of the voltage-gated sodium channel electrophysiology in neurons of target pests and nontarget species. The neurological actions of PYRs on non-neuronal cells of the nervous system remain poorly investigated. In the present work, we used C6 astrocytoma cells to study PYR actions (0.1-50&#8201;&#956;M) under the hypothesis that glial cells may be targeted by and vulnerable to PYRs. To this end, we characterized the effects of bifenthrin (BF), tefluthrin (TF), &#945;-cypermethrin (&#945;-CYP), and deltamethrin (DM) on the integrity of nuclear, mitochondrial, and lysosomal compartments. In general, 24- to 48-h exposures produced concentration-related impairment of cell viability. In single-compound, 24-h exposure experiments, effective concentration (EC)15s 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT assay) were computed as follows (in &#956;M): BF, 16.1; TF, 37.3; &#945;-CYP, 7.8; DM, 5.0. We found concentration-related damage in several C6-cell subcellular compartments (mitochondria, nuclei, and lysosomes) at&#8201;&#8805; 10-1 &#956;M levels. Last, we examined a mixture of all PYRs (ie, &#931; individual EC15) using MTT assays and subcellular analyses. Our findings indicate that C6 cells are responsive to nM levels of PYRs, suggesting that astroglial susceptibility may contribute to the low-dose neurological effects caused by these insecticides. This research further suggests that C6 cells may provide relevant information as a screening platform for pesticide mixtures targeting nervous system cells by expected and unexpected toxicogenic pathways potentially contributing to clinical neurotoxicity.","palabras_clave":"C6 CELLS|PYRETHROYDS|CELLULAR DAMAGE|CELL DEATH"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6299,"idioma_id":4,"titulo":"Ionic liquid mediated extraction, assisted by ultrasound energy, of available\/mobilizable metals from sediment samples","resumen":"A new extraction method for metals from sediment samples was developed. In this procedure, the chelating agent EDTA was combined with a minimal amount of the ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate (Bmim[BF4]), assisted by ultrasound energy. The available analytes ?Cd, Cr, Cu, Ni, Pb and Zn? were extracted under optimal conditions for a 12.5 ratio (extractant volume\/sample mass) with 0.005 mol L&#8722;1 EDTA solution, 0.1 mol L&#8722;1 NaHCO3, 5.0 mmol L&#8722;1 Bmim[BF4] and 7.0 min of sonication time, using an ultrasonic bath (output power of 160 W). The best extractions were obtained with 100 W (power dissipated in the liquid). These conditions were obtained applying the univariate method. It is important to highlight that the conventional method (extraction with 0.05 mol L&#8722;1 EDTA solution only) consumes 6 h to extract available metals from sediment samples selectively, and with the proposed procedure the extraction time is noticeable reduced to 7.0 min. Extractable metal concentrations obtained were measured by flame atomic absorption spectrometry. The results showed good agreement with those obtained by the conventional method using a Student?s paired t-test.","palabras_clave":"Extraction |Metals |Ionic liquid |Ultrasonic energy"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6303,"idioma_id":4,"titulo":"Systemic Transplantation of Bone Marrow Mononuclear Cells Promotes Axonal Regeneration and Analgesia in a Model of Wallerian Degeneration","resumen":"Background. Reinnervation timing after nerve injury is critical for favorable axonal regeneration, remyelination, and clinical improvement.Considering bonemarrowmononuclear cells (BMMC) are easily obtained and readily available for transplant, this workanalyzed the effect of BMMC systemic administration on nerve repair and pain behavior.Methods. Adult rats with sciatic nervecrush were immediately and systemically injected BMMC through the caudal artery. Nontreated, sham and naïve rats were alsoincluded. Histological, immunohistochemical, biochemical, functional, and behavioral analyses were performed in nerves harvestedfrom each group at different survival times. Results. Axons in BMMC-treated rats exhibited a more conserved morphologicalappearance than those in nontreated rats, as observed at different survival times both in semithin sections andultrastructural analysis. BMMC-treated rats also showed a reduction in major myelin protein immunoreactive clusters 7 and14 days postinjury, as compared with nontreated rats. Electrophysiological analysis showed BMMC treatment to slightly improvethe amplitude of compound muscle action potential starting at 14 days postinjury. Finally, mechanical withdrawal threshold revealeda full preventive action against transient mechanical hypersensitivity in BMMC-treated rats. Conclusions. These datademonstrate the efficiency of BMMC, systemically and noninvasively transplanted, in correcting morphological, functional and behavioralalterations resulting from peripheral nerve injury","palabras_clave":"MONONUCLEAR CELLS|SYSTEMIC TRANSPLANTATION |AXONAL REGENERATION |WALLERIAN DEGENERATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6320,"idioma_id":4,"titulo":"AGROCLIMATIC ZONING FOR LESQUERELLA FENDLERI, A MULTIPURPOSE OILSEED CROP FOR PRODUCTION IN ARGENTINA","resumen":"Lesquerella produces a small seed that has 25 to 30% oil that contains 55 to 64% hydroxy fatty acid. The oil is useful for industrial applications, cosmetics, pharmaceuticals and biodiesel. Lesquerella is valued for both its oil and gum. The gum has the potential to be used as a thickener in various industrial and food products.The aim of this paper was to develop an agro-climatic zoning model to determine the potential growing areas for Lesquerella fendleri in Argentina. To define the agroclimatic suitability of this crop in Argentina, the climatic data of the meteorological stations corresponding to the period 1981-2010 was analyzed. Based on international bibliography, the authors outlined an agro-climatic zoning model in Argentina for L. fendleri, where 7 classes of suitability were differentiated. This model may be applied to any part of the world, using the agroclimatic limits presented in this paper. This work has been made by the implementation of a Geographic Information System. The SIG database can be updated easily in the future with new data or with better spatial resolution data.","palabras_clave":"Lesquerella flenderi  |Bioclimatic requirements|Agroclimatic zoning|Subhumid to semiarid climate of Argentina."},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6321,"idioma_id":4,"titulo":"Possibilities for growing switch-grass (Panicum virgatum) as second generation energy crop in dry-subhumid, semiarid and arid regions of the Argentina","resumen":"Panicum virgatum (swich-grass) is cultivated in some countries to obtain biomass used in the production of heat, fiber, electricity and second generation ethanol. Currently, in Argentina, this species is used for forage and as an ornamental. The aim of this work was to design an agroclimatic zoning model for swich-grass in Argentina, both for upland and lowland ecotypes, based on its bioclimatic requirements and employing a Geography Information System. The variables taken into consideration were: average temperature during growing period and reproductive period, frost free days and rainfall during growing season. This work demonstrated that an ample region of the country is agro-climatically suitable for the implantation of switch-grass in rainfed conditions or with complementary irrigation. The agroclimatic zoning for the upland ecotype shows that suitability reaches latitudes of up to 46ºS, while the lowland ecotype can be grown up to 40ºS. Thornthwaite´s Moisture Index equal to zero was overlapped to the Argentinean agroclimatic zoning for upland and lowland types, to obtain the potential growing areas under dry-subhumid, semiarid to arid climates. The areas where switch-grass should be effectively tested are those categorized as optimal, very suitable, suitable, and very suitable\/suitable with irrigation, located to the West of TMI equal to zero, which include dry-subhumid (0 <TMI <-20), semiarid (-20 <TMI <-40) and arid (-40 <TMI <-60) climates. This agroclimatic zoning model can be applied to any region in the world, using the same bioclimatic indices and the classes delimited in this paper.NOTA: el Journal pertenece a otros países miembros de Europa Central, no solo a Bulgaria, sino también: Croacia, República Checa, Eslavania, Eslovenia, Rumania y Hungría.","palabras_clave":"agroclimatic zoning model|Argentina|bioclimatic requirements|dry-subhumid to arid climate|energy crop,"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6327,"idioma_id":5,"titulo":"CONDUCTAS DE RIESGO AUDITIVO Y ACCIÓN DEL MECANISMO DE PROTECCION COCLEAR EN ADOLESCENTES","resumen":"La exposición a ruido no ocupacional, como la música a alto nivel sonoro, constituye un creciente factor de riesgo de pérdida auditiva en adolescentes. Estudios internacionales postulan que una función importante del Sistema Eferente Medial (SEM) es proteger el oído interno frente al ruido mediante un mecanismo reflejo y que puede ser evaluado a través de la Supresión Contralateral (SC) de las otoemisiones acústicas transitorias (TEOAEs). El mecanismo subyacente de este fenómeno no se conoce en su totalidad y los antecedentes sobre el tema son escasos. En esta investigación se analizó la relación entre la Exposición General a Música (EGM), el estado de la función auditiva y el mecanismo de protección coclear. Participaron 91 adolescentes de 14\/15 años. Se evaluaron las siguientes dimensiones: a) psicosocial: EGM a través un cuestionario de actividades extraescolares; b) auditiva: funcionamiento del SEM mediante SC de las TEOAEs y evaluación de perfiles audiométricos mediante la audiometría. Los resultados mostraron que la SC no influyó estadísticamente en los perfiles audiométricos y categorías de exposición. Sin embargo los resultados de la SC se orientan hacia la menor magnitud de efecto supresor, disminución en la respuesta total en relación al descenso de los umbrales auditivos y en relación a las categorías ?alta? y ?baja? de EGM. Es necesario promover trabajos destinados al comportamiento de riesgo auditivo conjuntamente con el mecanismo protector del SEM. De esta manera se podrá contribuir en la identificación temprana de la sensibilidad auditiva en adolescentes expuestos a ruido no ocupacional.","palabras_clave":"exposición general a música|comportamiento de riesgo auditivo|sistema eferente medial|mecanismo de protección coclear|supresión contralateral de las otoemisiones acústicas|adolescentes"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6339,"idioma_id":4,"titulo":"Anatase-CMK-3 nanocomposite development for hydrogen uptake and storage","resumen":"The nanometric carbon CMK-3 modified with TiO2 in anatase phase was synthesized and applied to energy uptake and storage. TiO2 nanoclusters are important for hydrogen energy harvesting. The creation of porous structures or large surface with TiO2 nanoclusters inside can potentially face the challenge of improving their efficiency.In the present work, we report the synthesis and characterization of TiO2-CMK-3 material assembled from anatase nanoparticles dispersed in the nanometric carbon CMK-3. The resulting nanocomposite was characterized by X-ray diffraction, Raman spectroscopy, Transmission electron microscopy, X-ray photoelectron spectroscopy, Energy-dispersive X-ray spectroscopy and N2 adsorption-desorption analysis. The newly synthesized hybrid composites exhibited significantly enhanced H2 storage, in which CMK-3 ordered porous carbon modified with anatase nanoclusters proves material for hydrogen uptake. The nanoparticles of anatase (~5 nm) incorporated onto CMK-3 showed higher hydrogen uptake at low and high pressures (2.9 wt% of H2 sorption at 10 bar and 77 K) than CMK-3. The approach includes a discussion of H2 adsorption process and storage properties.","palabras_clave":"Nanocomposite|Anatase|CMK-3|Hydrogen,storage"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6417,"idioma_id":4,"titulo":"Development of garlic bioactive compounds analytical methodology based on liquid phase microextraction using response surface design. Implications for dual analysis: Cooked and biological fluids samples","resumen":"Organosulphur compounds (OSCs) present in garlic (Allium sativum L.) are responsible of several biological properties. Functional foods researches indicate the importance of quantifying these compounds in food matrices and biological fluids. For this purpose, this paper introduces a novel methodology based on dispersive liquid-liquid microextraction (DLLME) coupled to high performance liquid chromatography with ultraviolet detector (HPLC-UV) for the extraction and determination of organosulphur compounds in different matrices. The target analytes were allicin, (E)- and (Z)-ajoene, 2-vinyl-4H-1,2-dithiin (2-VD), diallyl sulphide (DAS) and diallyl disulphide (DADS). The microextraction technique was optimized using an experimental design, and the analytical performance was evaluated under optimum conditions. The desirability function presented an optimal value for 600 &#956;L of chloroform as extraction solvent using acetonitrile as dispersant. The method proved to be reliable, precise and accurate. It was successfully applied to determine OSCs in cooked garlic samples as well as blood plasma and digestive fluids.","palabras_clave":"garlic|dispersive liquid-liquid microextraction|HPLC"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6429,"idioma_id":5,"titulo":"TRANSITANDO LOS MÁRGENES: HACIA UNA INVESTIGACIÓN DE BORDE","resumen":"Motiva el presente trabajo la indagación acerca de la experiencia de investigar desde los márgenes de las ciencias sociales, o investigar desde los bordes. A partir de lecturas que nos acercaron a estas definiciones (Torres Carrillo, 2011), es que llegamos a la conclusión, o punto de partida para el pensamiento que desarrollaremos en el equipo de investigación, que compartimos la experiencia de sentirnos investigadoras de múltiples bordes. Bordes académicos, bordes socioeconómicos, bordes institucionales. En alguna medida, todos nos identificamos con algunos de estos bordes, y sobre esa experiencia es que estructuramos el presente escrito.Por lo tanto, les compartimos nuestro sentir-pensar en relación a la propuesta de investigar desde los márgenes, experiencia quizás sentida por los lectores de este artículo. A modo de sistematizar este sentir-pensar nuestro nos hicimos una serie de preguntas, que intentamos responder en este escrito, tales como ¿creemos viable la investigación de borde? ¿En qué planos o aspectos de nuestra existencia nos sentimos de borde? Y si ser investigador de borde requiere pensar en términos transdisciplinares y abrazar otros saberes, ¿cuáles serían esos otros saberes, donde los buscaríamos, o donde ellos nos encontrarían? Responderemos a estas inquietudes desde nuestras prácticas investigativas, ya sea como estudiantes o como profesores.","palabras_clave":"ABRAZO DE SABERES|INVESTIGACIÓN DE BORDE|PRÁCTICAS INVESTIGATIVAS|TRANSDISCIPLINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6432,"idioma_id":5,"titulo":"Actitudes hacia el sobrepeso y su asociación con riesgo de trastorno alimentario en niños: un estudio exploratorio.","resumen":"El objetivo de este estudio es explorar actitudes hacia el sobrepeso en niños\/as y analizar su asociación con riesgo de trastorno alimentario. Participaron 94 niños\/as escolarizados de edad promedio de 10.72 años. En una primera fase, completaron instrumentos autoadministrables. En una segunda fase, se realizó una entrevista diagnóstica con los probables casos de riesgo de trastorno alimentario. La mayoría de los niños evidencian una actitud negativa hacia el sobrepeso, sin diferencias por sexo ni por índice de masa corporal. A su vez, se identificó una asociación significativa pero débil entre actitud hacia el sobrepeso y riesgo de trastorno alimentario. En conclusión, se sugiere el abordaje de esta problemática en los programas orientados a la prevención de trastornos alimentarios.","palabras_clave":"TRASTORNOS ALIMENTARIOS|ACTITUDES|SOBREPESO|NIÑOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6438,"idioma_id":4,"titulo":"Host-pathogen relationships between the chytrid fungus Batrachochytrium  dendrobatidis and tadpoles of five South American anuran species","resumen":"The chytrid fungus Batrachochytrium dendrobatidis (Bd) is one of the most important contributors for the decline of amphibian populations worldwide. Evidence indicates that the harmfulness of Bd infection depends on the species and life stage, the fungus strain, the season and environmental factors. In the present paper, we experimentally investigated (i) the susceptibility and sensitivity of five South American tadpole species (Rhinella fernandezae, Scinax squalirostris, Hypsiboas pulchellus, Leptodactylus latrans, and Physalaemus fernandezae) to a foreign Bd strain (JEL423), (ii) the response of two populations of P. fernandezae to a native Bd strain (MLA1), and (iii) the virulence of native and foreign Bd isolates on tadpoles of the same species. We also evaluated the relationship between Bd infection and the loss of keratinized mouthparts in P. fernandezae. We found that all species except L. latrans were susceptible to Bd infection with lethal consequences, with R. fernandezae being the most sensitive species. In P. fernandezae, sensitivity to infection depended on population as well as Bd strain, although no relationship was found between fungal infection and the loss of keratinized mouthparts. This is the first experimental study on mortality rates of South American tadpoles exposed to Bd.","palabras_clave":"Batrachochytrium dendrobatidis|fungal infection|South America|tadpoles"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6447,"idioma_id":4,"titulo":"Nucleolar activity in Triticum x Thinopyrum hybrids with different ploidy level","resumen":"The activity of nucleolar organizer regions (NORs) and the presence of ribosomal DNA28 (rDNA) zones were studied in two Triticum x Thinopyrum hybrids: a hexaploid hybrid29 with 2n=42 chromosomes, named trigopiro SH16 INTA, and a decaploid hybrid with30 2n=56 chromosomes, named trigopiro Don Noé INTA. The use of the pTa71 probe31 revealed the presence of ten rDNA signals in both hybrids, whereas the Ag-NORs32 technique showed ten signals in SH16 and eight in Don Noé. We concluded that all33 trigopiro SH16 INTA NORs are active and that the activity of one NOR pair of34 trigopiro Don Noé INTA is suppressed. Therefore, the amphiplasty phenomenon is35 present in trigopiro Don Noé INTA but not in trigopiro SH16 INTA.","palabras_clave":"TRITICUM|THINOPYRUM|AG-NOR|PTA71|IN SITU HYBRIDIZATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6512,"idioma_id":5,"titulo":"Identificación de QTL en las generaciones segregantes de un híbrido de segundo ciclo de tomate","resumen":"El objetivo fue detectar QTL de interés agronómico en las generaciones segregantes (F 2  y  retrocruzas) de un híbrido de segundo ciclo (HSC) de tomate (Solanum lycopersicum L.),obtenido entre dos líneas endocriadas recombinantes derivadas del cruzamiento interespecífico S. lycopersicum cv. Caimanta x S. pimpinellifolium LA 722. La caracterizaciónmolecular se hizo por marcadores AFLP mientras que los caracteres morfológicos anali-zados fueron peso, diámetro, altura, contenido en sólidos solubles, acidez, color, pH,forma, dureza y vida poscosecha de los frutos. Para identificar QTL, la asociación entrebandas polimórficas y caracteres cuantitativos con variancia genética significativa serealizó por el análisis de único punto. Con seis combinaciones de cebadores, seleccio-nadas por detectar elevado porcentaje de polimorfismo, se obtuvo 221 bandas de lascuales 135 (61,1%) fueron polimórficas. En la F 2 , 29 fragmentos polimórficos siguieronla distribución mendeliana esperada, identificándose un total de 28 QTL para todos loscaracteres analizados. En las retrocruzas, 15 fragmentos polimórficos siguieron unasegregación mendeliana 1:1 (detectándose en 12 de ellas un comportamiento de novo)y se identificó en total 13 QTL para los caracteres contenido en sólidos solubles, altura,peso y forma del fruto. Los AFLP permitieron identificar QTL de importancia agronómica en las generaciones segregantes del HSC de tomate.","palabras_clave":"Solanum seccióin Lycopersicon|MEJORAMIENTO GENÉTICO VEGETAL|RECURSOS FITOGENÉTICOS|CALIDAD DE FRUTO|VIDA POSCOSECHA|BIOTECNOLOGÍA VEGETAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6560,"idioma_id":4,"titulo":"Comparative study using video analysis and an ultrasonic measurement system to quantify mandibular movement","resumen":"Objectives: This study provides a direct comparison between two registration systems used in quantifying mandibular opening movements: two-dimensional videography and electronic axiography, which is used as a reference. Method: A total of 32 volunteers (age: 27.2 ± 6.8?gender: 17 F?15 M) participated in the study and repeated a characteristic movement, the frontal Posselt, used in the clinical evaluation of the temporomandibular joint. Results: Frontal Posselt diagrams were reconstructed with the data gathered from both systems, which yielded acceptably similar data. Three commonly assessed parameters were obtained from each diagram and compared. These parameters were: maximum opening, right laterotrusion and left laterotrusion. Both descriptive statistics and the ANOVA test suggested that there was no significant difference between the estimated maximum opening parameter and the reference system (p = 0.217, 95% confidence). Laterotrusion values, on the other hand, appear to be overestimated by videography system and to show greater variability. Discussion: Two-dimensional videography appears to be a suitable tool with resolution that is adequate for tracing mandibular movements?and opening values, in particular?for screening purposes, long-term observation, and as a quick check for dysfunction as far as frontal plane trajectories are concerned. Conclusion: Reliability and acceptable quality of 2D videography data, acquired in this work, show that it has clear advantages for its wide application in the dental office due to simplicity and low cost for maximum opening measurement given the usefulness of this parameter in the detection of temporomandibular disorders.","palabras_clave":"2D Videography|Jaw movement|Maximum opening|Temporomandibular join"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6573,"idioma_id":4,"titulo":"Comparison of two cooling protocols for llama semen: with and without collagenase and seminal plasma in the medium","resumen":"Seminal plasma (SP) of South American Camelids could interfere with the interaction of spermatozoa with the extenders; therefore it becomes necessary to improve semen management using enzymatic treatment. Our objective was to compare two cooling protocols for llama semen. Twelve ejaculates were incubated in 0.1% collagenase and then were divided into two aliquots. One was extended in lactose and egg yolk (LEY) (Protocol A: collagenase and SP present). The other aliquot was centrifuged, and the pellet was resuspended in LEY (Protocol B: collagenase and SP absent). Both samples were maintained at 5°C during 24 hr. Routine and DNA evaluations were carried out in raw and cooled semen. Both cooling protocols maintained sperm viability, membrane function and DNA fragmentation, with Protocol A showing a significantly lowered total and progressive motility (p < .05) and Protocol B showing a significant increase in chromatin decondensation (p < .05). Protocol A avoids centrifugation, reducing processing times and making application in the field simpler. However, as neither protocol showed a significant superiority over the other, studies should be carried out in vivo to evaluate the effect on pregnancy rates of the presence of collagenase and SP in semen samples prior to either cooling or freeze-thawing.","palabras_clave":"LLAMA|COLLAGENASE|COOLING|SEMEN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6587,"idioma_id":4,"titulo":"Hepato and Cardiotoxicity of Chemotherapeutic Treatment Evaluated by Means of Small Animal Imaging","resumen":"Background: Chemotherapy is one of the most common approaches for cancer treatment. Particularly Doxorubicin has been proven to be effective in the treatment of many soft and solid tumors for locally advanced and metastatic cancer. It is not easy to clinically evaluate the chemotoxic or chemoprotective effect of some drugs, even more when there is a subclinical toxicity. Objective: To determine the usefulness of the hepatobiliary, colloid and cardiac scintigraphies, employing 99mTc-disida, 99mTc-phytate and 99mTc-sestamibi respectively, in the evaluation of the hepato and cardiotoxicity of two chemotherapeutic treatments assessed in rats. Method: Two groups were submitted to doxorubicin (DOX) treatment and one was co-administered with histamine (DOX+HIS). Static 99mTc-phytate and 99mTc-sestamibi scintigraphies as well as a dynamic 99mTc-disida study were performed in a small field of view gamma camera at: 0 weeks (control), 1 week and 2 weeks of treatment. Imagenological parameters were calculated: Liver\/Bone Marrow ratio (L\/BM), Heart\/Background ratio (H\/B) and time to the maximum (Tmax) for 99mTc-phytate, 99mTc-sestamibi and 99mTc-disida extraction, respectively. Results: Control (L\/BM= 98±3; H\/B=2.3±0.4; Tmax=8±3), DOX (L\/BM: 85±3, 80±3; H\/B, 3.5±0.5, 3.3±0.5 and Tmax 6±1, 4±1) for 1 and 2 weeks respectively and DOX+HIS (L\/BM: 99±0.3, 98±1; H\/B 2.9±0.5, 2.9±0.5 and Tmax, 8±2, 9±2) for 1 and 2 weeks, respectively. Histological analysis showed cardio and hepatotoxicity induced by doxorubicin. Conclusion: Imagenological parameters showed differences among treated and control groups and between both chemotherapy treatments. Thus, these radiopharmaceutical functional approaches were able to reflect heart and liver toxicity produced by doxorubicin.","palabras_clave":"DOXORUBICIN|CARDIOTOXICITY|HEPATOTOXICITY|SMALL ANIMAL IMAGING"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6649,"idioma_id":4,"titulo":"Taxonomic and cytogenetic studies in Opuntia ser. Armatae (Cactaceae)","resumen":"Opuntia series Armatae is evaluated considering morphological (vegetative, floral and carpological) and cytogenetical (diploid number, presence of heterochromatin and physical localization of ribosomal genes) features to shed light on their systematics and evolution. Three complexes (named O. elata, O. megapotamica and O. monacantha) are proposed to accommodate seven species according to the tepal, fruit, stigma and seed aril traits. Additional systematic conclusions include: 1. O. stenarthra, O. assumptionis, O. cognata and O. subsphaerocarpa are synonyms; 2. O. elata is a variable species with two varieties: var. cardiosperma and var. obovata; 3. O. rioplatense is a synonym of O. elata var. obovata and 4. O. megapotamica is a polymorphic species with two varieties (one newly described and a new combination). All species had small similar-sized symmetrical chromosomes and were tetraploid (2n=44), except for a population of O. arechavaletae and O. monacantha (2n=22). All showed one or two pairs with CMA+\/DAPI?NOR associated bands. The 18-5.8-26S rDNA loci seem to coincide with CMA+\/DAPI-\/NORs blocks. The number of 5S signals detected was proportional to the ploidy level of the species. A combination of cytogenetic and morphological features helped to differentiate the complexes, species, and varieties of Opuntia ser. Armatae.","palabras_clave":"TAXONOMIA|CITOGENETICA|OPUNTIA|CACTACEAE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6670,"idioma_id":4,"titulo":"The conundrum of UDP-Glc entrance into the yeast ER lumen","resumen":"UDP-Glc entrance into the endoplasmic reticulum (ER) ofeukaryotic cells is a key step in the quality control of glycoprotein folding,a mechanism requiring transfer of a Glc residue from the nucleotide sugar toglycoprotein folding intermediates by the UDP-Glc:glycoproteinglucosyltransferase (UGGT). According to a bioinformatics search there are onlyeight genes in the Schizosaccharomycespombe genome belonging to the three Pfam families to which all knownnucleotide sugar transporters (NST) of the secretory pathway belong. Theprotein products of two of them (hut1+and yea4+) localizeto the ER, those of genes gms1+,vrg4+, pet1+, pet2+and pet3+ to the Golgi,whereas that of gms2+ hasan unknown location. Here we demonstrate that: 1) Dhut1 and &#916;gpt1 (UGGT null) mutants share severalphenotypic features; 2) Dhut1 mutants show a 50% reduction in UDP-Glc transport intoER-derived membranes; 3) in vivoUDP-Glc ER entrance occurred in &#916;hut1&#916;yea4&#916;gms2mutants and in cells in which &#916;hut1disruption was combined with that of each of four of the genes encodingGolgi-located proteins. We conclude that the hut1+ gene product is involved in UDP-Glc entrance intothe ER, but that at least another as yet unknown NST displaying anunconventional sequence operates in the yeast secretory pathway as disruptionof all genes whose products localize to the ER or have an unknown location didnot obliterate UDP-Glc ER entrance. This conclusion agrees with our previousresults showing that UDP-Glc entrance into the yeast ER does not follow the classicalNST antiport mechanism. ","palabras_clave":"N-linked glycosylation|nucleotide-sugar transporter |UDP-Glc|Endoplasmic reticulum (ER)"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6682,"idioma_id":4,"titulo":"Horticulturists and oxygen ecozones in the tropical and subtropical forests of Southeast South America","resumen":"We analyse the isotopic values (&#948;13C, &#948;15N) of the diet of pre-Columbian horticulturalist populations from tropical and subtropical areas of southeastern South America, belonging to the Guarani and Taquaraarchaeological units. The data indicate different trends in each one (T = 4.21; P = 0.0004), showing a mixed diet with maize consumption in the Guarani samples (&#948;13Cco = &#8722;15.5 ± 1.8?; &#948;13Cap &#8722;10.4 ± 0.8?) and a depleted one in the Taquara ones (&#948;13Cco &#8722;18.2 ± 1.7?; &#948;13Cap &#8722;11.9 ± 0.9?), with a significant internal dispersion in both populations. The first population has higher nitrogen values (&#948;15N11.1 ± 0.6?) compared to the Taquara samples (&#948;15N 9.3 ± 1?), suggesting a more carnivorous diet. The recognition of these pre-Columbian mixed diets involves the identification of maize cultivation on theAtlantic side of the southernmost area of South America (Parana Delta, 34° SL). Through the analysis of &#948;18O we have identified two isotopic ecozones, the first along the Paraná River Valley, with an averagevalue of &#948;18O &#8722;3.7 ± 0.5? (CV = 13.5%; CI = &#8722;3.83 \/ &#8722;3.16), and the second one, located in the Planalto of southern Brazil (Araucaria Forest), with a mean value of &#948;18O &#8722;1.5 ± 0.3? (CV = 16.5%;CI = &#8722;1.69 \/ &#8722;1.29). The isotopic data (&#948;13C, &#948;15N and &#948;18O) suggest human movements between these two ecozones.","palabras_clave":"CARBON|NITROGEN|OXIGEN|ISOTOPES|SOUTH AMERICA|HORTICULTURALISTS|MAIZE|GUARANI|TAQUARA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6698,"idioma_id":4,"titulo":"Uptake, distribution in different  Tissues, and genotoxicity of imidacloprid in the freshwater fish  Australoheros facetus.","resumen":"Abstract: The neonicotinoid imidacloprid is under re-evaluation by regulatory agencies because of the poor current information available regarding its potential effects. One of the goals of the present study was to determine imidacloprid uptake and distribution in the freshwater fish Australoheros facetus experimentally exposed for 24 h and 48 h to 100ug\/L, 300 ug\/L, and 2500 ug\/L. The toxicity of imidacloprid to fish reported in the literature is in the milligrams per liter or gram per liter range, but sublethal effects at micrograms per liter in some groups other than fish have been described. Another goal of the present study was to evaluate imidacloprid?s potentialgenotoxicity and to compare it between the individual compound and a commercial formulation. Concentrations of imidacloprid were measured in water, brain, muscle, gills, gut, liver, and blood by liquid chromatography-tandem mass spectrometry. Imidacloprid was detected in all the tissues tested. Concentrations were higher after 48 h than after 24 h in liver, gills, gut, and muscle, whereas in brain and blood they were similar at both exposure times. Although there was no accumulation, only uptake, of imidacloprid, genotoxicity was observed. In fish exposed to IMIDA NOVA 35, increased micronucleus frequency at 100 ug\/L and 1000 ug\/L was detected, whereas in the imidacloprid active ingredient bioassay it increased only at 1000 ug\/L imidacloprid. The present findings warn of the possible consequences that fish living in freshwater ecosystems can suffer.","palabras_clave":"CONTAMINANTS OF EMERGING CONCERN   |FISHES|BIOACCUMULATION|GENOTOXICITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6724,"idioma_id":4,"titulo":"Lithium Naphthalenides in Non-Polar or in Low Polarity Media: Some Insights Regarding their Use as Initiators in Anionic Polymerizations","resumen":"The synthesis of bidirectional anionic initiators by the reaction between metallic lithium (Li) and naphthalene (Naph), under mild conditions, in non-polar (benzene) or low-polarity media (benzene\/THF mixtures) is reported. The ef&#64257;ciency of these initiators to provide macromolecules with well-de&#64257;ned structures was demonstrated. Model linear homopolymers from styrene (S) or hexamethyl(ciclotrisiloxane) (D3) monomers were synthesized using classical anionic polymerization (high-vacuum techniques). The model polymers obtained were analyzed using the conventional analytical techniques, and showed narrow molar mass distributions, a broad range of molar masses (from 3000 to 1,000,000 g\/mol) and polydispersity indexes (Mw\/Mn) lower than 1.1. High molar mass polymers were obtained using pure benzene as solvent, whereas lower molar masses were obtained in benzene\/THF mixtures in which the concentration of THF was lower than 10 % v\/v. The ratio [Li]\/[Naph] and the nature of the reaction medium are the experimental parameters to be controlled to obtain the desired lithium naphthalenides.","palabras_clave":"LITHIUM NAPHTALEINIDES INICIATOR|ANIONIC POLYMERIZATION|POLYSTYRENE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6725,"idioma_id":4,"titulo":"Anionic ring opening polymerization of e caprolactone initiated by lithium silanolates","resumen":"Ring-opening homo- and co-polymerization reactions of &#1013;-caprolactone were performed by employing anionic polymerization (high vacuum techniques) and lithium silanolates (LS) as initiators. LS were obtained by reaction between hexamethyl(cyclotrisiloxane) and sec-Bu-Li+, or from living poly(dimethylsiloxanyl)lithium chains. The results indicated that LS are efficient initiators for the ring-opening polymerization of &#1013;-caprolactone, providing the respective homogeneous polymers in good yields.","palabras_clave":"Anionic Ring Opening Polymerization |£-Caprolactone |Lithium Silanolates"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6797,"idioma_id":4,"titulo":"Pathogens, parasites, and parasitoids associated with bumble bees (Bombus spp.) from Uruguay","resumen":"As elsewhere in the world, bumble bees play a vital role as pollinators in Uruguay, but knowledge on their health status is still limited. Between September 2012 and May 2013, 403 adult individuals of the two species of Bombus known for the country (B. atratus, B. bellicosus) were collected in six localities. We found that 177 (119 B. atratus, 58 B. bellicosus) were harboring one or two types of pathogens, parasites or parasitoids. Identification of these natural enemies carried out by morphological or molecular procedures revealed the presence of two species of Microsporidia [Nosema ceranae (Prevalence: 18.2 % in B. atratus; 44.9 % in B. bellicosus), Tubulinosema pampeana (Prev.: 13 % in B. atratus)], two species of Nematoda [Sphaerularia bombi (Prev.: 40.4 % in B. atratus; 40 % in B. bellicosus) and an unidentified Mermithidae (Prev.: 0.8 % in B. bellicosus)], and one species of Diptera parasitoid [Prev.: 3.2 % in B. atratus; 4.2 % in B. bellicosus]. Except N. ceranae, none of the other species have been previously reported in Uruguay","palabras_clave":"Conopidae |Microsporidia |Nematoda |Pollinator"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6799,"idioma_id":5,"titulo":"Efecto del estrés social agudo sobre impulsividad, toma de riesgos y sesgos atencionales en jóvenes con y sin historia familiar de abuso de alcohol","resumen":"El objetivo del presente trabajo fue analizar el efecto del estrés social ? inducido experimentalmente -- en jóvenes entre 18 y 30 años con historia familiar positiva (HFP) o negativa (HFN) de abuso de alcohol. Se midió la percepción subjetiva del estado emocional y el desempeño en pruebas que miden atención hacia estímulos que señalizan al alcohol (STROOP Emocional), impulsividad (SKIP) y conductas de riesgo (BART), y también se midieron los niveles de cortisol en saliva. Se utilizó un diseño factorial 2 (varón, mujer) x 2 (HFP, HFN) x 2 (tratamiento, control), con mediciones pre- y post-test. Los participantes expuestos al estrés tuvieron, comparados con los controles, niveles más altos de cortisol en saliva y una percepción subjetiva de mayor malestar y de menor bienestar. Los HFP reportaron un nivel significativamente menor de bienestar (i.e., menor calma, tranquilidad y relajación) y de mayor malestar (i.e., mayor nerviosismo) que sus pares HFN. No se encontraron efectos significativos de tratamiento, ni interacciones significativas entre tratamiento y HF, en las pruebas de medir impulsividad, conductas riesgosas y sesgos atencionales.","palabras_clave":"alcohol|jovenes|impulsividad|rasgo"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6809,"idioma_id":5,"titulo":"Determinación de la eficiencia de la micropropagación de genotipos de mandioca (Manihot esculenta, Euphorbiaceae) de interés para el Nordeste Argentino.","resumen":"Numerosos trabajos de propagación in vitro de mandioca se han citado, sin embargo, la eficiencia de la multiplicación sólo se ha establecido para un número muy restringido de cultivares y\/o subcultivos. Con el objeto de evaluar el comportamiento in vitro de 20 cultivares de mandioca de interés para el Nordeste Argentino durante la fase de multiplicación (6 subcultivos totales realizados cada 30 días), se cultivaron segmentos uninodales en medio basal de Murashige y Skoog (1962) más 0,01 mg\/L de ácido 1-naftalenacético, 0,01 mg\/L de 6-bencilaminopurina y 0,1 mg\/L de ácido giberélico. En el 100% de los cultivares fue posible la regeneración de plantas durante los 6 subcultivos. Independientemente del subcultivo, el número promedio de nudos regenerados por explante varió significativamente con el cultivar (P&#61603;0,0001), rondando valores de 2 a 5 nudos. El número promedio de nudos acumulados fue significativamente distinto dependiendo del cultivar, alcanzando valores de 46 a 16.568 nudos totales (P&#61603;0,0001). Fue posible distinguir 3 grupos de cultivares, en relación a su capacidad de propagación y de crecimiento en longitud. El conocimiento de la tasa de multiplicación de distintos cultivares de mandioca permitirá ajustar los protocolos para optimizar la eficiencia de la micropropagación de mandioca.","palabras_clave":"Efecto del genotipo|Micropropagación|Subcultivos|Tasa de multiplicación|Mandioca"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6817,"idioma_id":5,"titulo":"La Economía en la formación de los Licenciados en Turismo","resumen":"La formación de los licenciados en turismo en Argentina incluye asignaturas de economía porque se coincide en reconocer su importancia para el ejercicio profesional. El peso de estas materias en la currícula difiere según la inserción institucional de la carrera y su vinculación con un área de investigación todavía en consolidación: la economía del turismo. Ante la diversidad de situaciones observadas, surge el interrogante sobre la posibilidad de integrar diferentes corrientes de pensamiento en una asignatura y se propone una discusión teórica en base a tres ejes epistemológicos: el turismo como campo de conocimiento abierto e interdisciplinario; la economía como ciencia social en la que se superponen teorías y paradigmas; y el pensamiento complejo. A partir de la revisión de contenidos mínimos y programas que se dictan en las universidades públicas del país, se propone un conjunto de temas económicos para la formación de los profesionales en turismo.","palabras_clave":"ECONOMÍA DEL TURISMO|PENSAMIENTO COMPLEJO|PARADIGMAS|LICENCIATURA EN TURISMO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6839,"idioma_id":4,"titulo":"TNF&alpha;-induced mucin 4 expression elicits trastuzumab resistance in HER2-positive breast cancer","resumen":"Purpose: Although trastuzumab administration improved the outcome of HER2-positive breast cancer patients, resistance events hamper its clinical benefits. We demonstrated that TNF&#945; stimulation in vitro induces trastuzumab resistance in HER2-positive breast cancer cell lines. Here, we explored the mechanism of TNF&#945;-induced trastuzumab resistance and the therapeutic strategies to overcome it. Experimental Design: Trastuzumab-sensitive breast cancer cells, genetically engineered to stably overexpress TNF&#945;, and de novo trastuzumab-resistant tumors, were used to evaluate trastuzumab response and TNF&#945;-blocking antibodies effectiveness respectively. Immunohistochemistry and antibody-dependent cell cytotoxicity (ADCC), together with siRNA strategy, were used to explore TNF&#945; influence on the expression and function of its downstream target, mucin 4 (MUC4). The clinical relevance of MUC4 expression was studied in a cohort of 78 HER2-positive breast cancer patients treated with adjuvant trastuzumab. Results: TNF&#945; overexpression turned trastuzumab-sensitive cells and tumors into resistant ones. Histopathologic findings revealed mucin foci in TNF&#945;-producing tumors. TNF&#945; induced upregulation of MUC4 that reduced trastuzumab binding to its epitope and impaired ADCC. Silencing MUC4 enhanced trastuzumab binding, increased ADCC, and overcame trastuzumab and trastuzumab-emtansine antiproliferative effects in TNF&#945;-overexpressing cells. Accordingly, administration of TNF&#945;-blocking antibodies downregulated MUC4 and sensitized de novo trastuzumab-resistant breast cancer cells and tumors to trastuzumab. In HER2-positive breast cancer samples, MUC4 expression was found to be an independent predictor of poor disease-free survival (P = 0.008). Conclusions: We identified TNF&#945;-induced MUC4 expression as a novel trastuzumab resistance mechanism. We propose MUC4 expression as a predictive biomarker of trastuzumab efficacy and a guide to combination therapy of TNF&#945;-blocking antibodies with trastuzumab.","palabras_clave":"BREAST CANCER|TNF|MUCIN 4|TRASTUZUMAB"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6847,"idioma_id":5,"titulo":"Contribuciones empíricas para la validez de grupos contrastados de la Batería de Tareas de Autorregulación Cognitiva (TAC)","resumen":"Los déficit de las funciones ejecutivas (FE)suelen estar presentes en el Trastorno por Déficitde Atención e Hiperactividad (TDAH). Distintostrabajos mostraron algunas falencias vinculadas ala medición de las FE, como la participación deotros procesos que no constituyen objeto de laevaluación. En el trabajo que se informa se analizaronlas diferencias existentes en las FE de niñoscon y sin diagnóstico de TDAH y se buscó identificary establecer aquellas variables con mayorpoder discriminante para la probabilidad de pertenenciaa ambos grupos. Se utilizaron las tareade la batería denominada Tareas de AutorregulaciónCognitiva (TAC), diseñadas ad-hoc para evaluarespecífica y relativamente en forma independientecada FE. Se trabajó con una muestra de 49niños escolarizados de 7 a 12 años de edad, de ambosgéneros, divididos en dos grupos, uno clínicode 19 niños con diagnóstico de TDAH, con unamedia de edad igual a 9.84 años(DE = 1.83) y unocontrol de 30 niños sin diagnóstico de TDAH conuna media de edad igual a 10.27 años (DE = .82),equiparados por género, edad, niveles socioeconómicoy educacional. Los resultados mostraronque el análisis discriminante permitió clasificar correctamenteal 98% de los participantes. Las tareas mejor discriminadas fueron la de Flexibilidadcognitiva y Control inhibitorio comportamental,con un 98.9% y 97.8%, respectivamente, de casoscorrectos. Esto muestra que la TAC constituyeuna batería con adecuada sensibilidad y especificidadpara discriminar y detectar casos de TDAHcon un elevado nivel de confiabilidad y porcentajede correctos clasificados","palabras_clave":"FUNCIONES EJECUTIVAS|TAREAS DE AUTORREGULACION COGNITIVA|TDAH|VALIDEZ DE GRUPOS CONTRASTADOS|CURVAS ROC"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6848,"idioma_id":4,"titulo":"Modulation of immune and antioxidant responses by azinphos-methyl in the freshwater  mussel Diplodon chilensis challenged with Escherichia coli","resumen":"The aim of the present study was to characterize the immune response?total hemocyte number, cell type proportion, hemocyte viability, lysosomal membrane stability, phagocytic activity, cellular acid and alkaline phosphatase activity, and humoral bacteriolytic and phenoloxidase activity?­in Diplodon chilensis exposed to 0.2 mg\/L of azinphos-methyl (AZM), using Escherichia coli as immunological and pro-oxidant challenges. In addition, glutathione-S-transferase and lipid peroxidation thiobarbituric acid reactive substances were analyzed in gill tissue. Mussels from an unpolluted site were treated for 3 d as follows: 1) experimental control; 2) solvent effects control (acetone 0.01%); 3) bacterial challenge effects control (E. coli, 5 cells\/mL × 104 cells\/mL); 4) pesticide effects control (AZM in acetone); 5) control for combined effects of solvent and bacterial challenge; and 6) exposed to AZM, then challenged with E. coli. The results showed increased granulocyte proportion and phagocytic activity. Partial reversion of deleterious effects of E. coli on lysosomal membranes was observed in mussels exposed to AZM and then challenged with E. coli. Total hemocyte number and humoral bacteriolytic activity were increased only by E. coli challenge. Acid phosphatase activity was increased by both E. coli and AZM, whereas the stimulating effect of E. coli on alkaline phosphatase activity was negatively modulated by AZM. Azinphos-methyl inhibited phenoloxidase activity regardless of the E. coli challenge. Gill glutathione-S-transferase activity was increased by E. coli treatment either alone or pretreated with acetone or AZM and by AZM alone. Thiobarbituric acid reactive substance levels were reduced by AZM alone or combined with the E. coli challenge and by acetone followed by the E. coli challenge. Both acetone and AZM seem to be important modulators of immune and antioxidant responses in D. chilensis. Environ Toxicol Chem 2017;36:1785?1794. © 2016 SETAC.","palabras_clave":"AQUATIC INVERTEBRATES|IMMUNOTOXICITY|ORANOPHOSPHORUS INSECTICIDE|STRESS RESPONSE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6856,"idioma_id":4,"titulo":"Optimized Switching Sequence for Multiphase Power Converters Under Inductance Mismatch","resumen":"Multiphase power converters allow to reduce semiconductor stress and to improve total ripple characteristics, when compared to a single phase converter. Semiconductor stress is reduced by dividing the total current among the N parallel-connected converters or phases. Furthermore, total ripple amplitude is reduced and its frequency increases to N times the switching frequency by interleaving each phase current ripple, which lessens the requirements on the total current filtering. These improvements, however, are detrimented mainlyby mismatches among the phase inductors value, leading to different ripple amplitudes among phases. As a consequence, when compared to the ideal case, total ripple amplitude is increased, ripple cancellation points are lost, and switching frequency component and its N-1 harmonics are generated. This paper proposes a method to mitigate this problem by selecting the phase switching sequence, in converters operating in the continuous conduction mode (CCM), which minimizes the switching frequency component and its harmonics in the total ripple. The proposed method efficiently finds the proper switching sequence for any number of phases, by using a previously presented current ripple characterization as the objective function for the optimization procedure. Simulations validate the proposal and show the improvement, when compared to another strategy present in the literature, which uses the switching sequence modification principle.","palabras_clave":"Multiphase power converters|current ripple|genetic algorithms|switching sequence"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6867,"idioma_id":4,"titulo":"Incidence of osmophilic yeasts and Zygosaccharomyces rouxii during the production of concentrate grape juices","resumen":"Zygosaccharomyces rouxii is the main spoilage yeast of grape juice concentrates. Detection and identification of Z. rouxii during the production of grape juice concentrate is critical to prevent spoilage in the final product. In this work, three grape juice concentrate processing plants were assessed by identifying osmophilic yeasts in juices and surfaces during different stages of a complete production line. Subsequently, molecular typing of Z. rouxii isolates was done to determine the strain distribution of this spoilage yeast. Osmotolerant yeast species, other than Z. rouxii, were mainly recovered from processing plant environments. Z. rouxii was only isolated from surface samples with grape juice remains. Z. rouxii was largely isolated from grape juice samples with some degree of concentration. Storage of grape juice pre-concentrate and concentrate allowed an increase in the Z. rouxii population. A widely distributed dominant molecular Z. rouxii pattern was found in samples from all three processing plants, suggesting resident microbes inside the plant.","palabras_clave":"OSMOPHILIC YEASTS|PROCESSING LINE|SPOILAGE YEASTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6907,"idioma_id":4,"titulo":"Resistance to citrus canker induced by a variant of Xanthomonas citri ssp. citri is  associated with a hypersensitive cell death response involving autophagy- associated vacuolar processes","resumen":"Xanthomonas citri ssp. citri (X. citri) is the causal agent of Asiaticcitrus canker, a disease that seriously affects most commerciallyimportant Citrus species worldwide. We have identified previouslya natural variant, X. citri AT, that triggers a host-specificdefence response in Citrus limon. However, the mechanismsinvolved in this canker disease resistance are unknown. In thiswork, the defence response induced by X. citri AT was assessedby transcriptomic, physiological and ultrastructural analyses, andthe effects on bacterial biofilm formation were monitored in parallel.We show that X. citri AT triggers a hypersensitive responseassociated with the interference of biofilm development andarrest of bacterial growth in C. limon. This plant responseinvolves an extensive transcriptional reprogramming, setting inmotion cell wall reinforcement, the oxidative burst and the accumulationof salicylic acid (SA) and phenolic compounds. Ultrastructuralanalyses revealed subcellular changes involving theactivation of autophagy-associated vacuolar processes. Our findingsshow the activation of SA-dependent defence in response toX. citri AT and suggest a coordinated regulation between the SAand flavonoid pathways, which is associated with autophagymechanisms that control pathogen invasion in C. limon. Furthermore,this defence response protects C. limon plants from diseaseon subsequent challenges by pathogenic X. citri. Thisknowledge will allow the rational exploitation of the plantimmune system as a biotechnological approach for the managementof the disease.","palabras_clave":"citrus canker resistance|hypersensitive response|salicylic acid|secondary metabolism|autophagy|biological control|biofilm formation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6917,"idioma_id":4,"titulo":"Essential Role of CFTR in PKA-Dependent Phosphorylation, Alkalinization and Hyperpolarization During Human Sperm Capacitation","resumen":"Mammalian sperm require to spend a limited period of time in the female reproductive tract to become competent to fertilize in a process called capacitation. It is well established that HCO3 &#8722; is essential for capacitation because it activates the atypical soluble adenylate cyclase ADCY10 leading to cAMP production, and promotes alkalinization of cytoplasm, and membrane hyperpolarization. However, how HCO3 &#8722; is transported into the sperm is not well understood. There is evidence that CFTR activity is involved in the human sperm capacitation but how this channel is integrated in the complex signaling cascades associated with this process remains largely unknown. In the present work, we have analyzed the extent to which CFTR regulates different events in human sperm capacitation. We observed that inhibition of CFTR affects HCO3 &#8722;-entrance dependent events resulting in lower PKA activity. CFTR inhibition also affected cAMP\/PKA-downstream events such as the increase in tyrosine phosphorylation, hyperactivated motility, and acrosome reaction. In addition, we demonstrated for the first time, that CFTR and PKA activity are essential for the regulation of intracellular pH, and membrane potential in human sperm. Addition of permeable cAMP partially recovered all the PKA-dependent events altered in the presence of inh-172 which is consistent with a role of CFTR upstream of PKA activation. J. Cell. Physiol. 232: 1404?1414, 2017. © 2016 Wiley Periodicals, Inc.","palabras_clave":"SPERM| capacitation|cystic fibrosis transmembrane conductance regulator (CFTR)|protein kinase A (PKA)"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6920,"idioma_id":5,"titulo":"ARGENTINA EN EL ESPACIO: POLÍTICA INTERNACIONAL EN RELACIÓN A LA POLÍTICA TECNOLÓGICA Y EL DESARROLLO INDUSTRIAL","resumen":"Elpresente trabajo se propone analizar medio siglo de tecnologíaespacial en la Argentina como un caso de desarrollo de una tecnologíacapital intensiva, considerada ?sensible? por los paísescentrales, en un contexto de país semiperiférico. Esta tecnologíaimplica niveles importantes de industrialización, pero también depoder militar. El objetivo es mostrar de qué manera una serie derupturas políticas y económicas transformaron los objetivos quedebían orientar la trayectoria del desarrollo de tecnologíaespacial, que es de uso civil y bélico. Este artículo tambiénexplica cómo funcionan las Relaciones Internacionales a partir deuna política tecnológica.","palabras_clave":"TECNOLOGÍAS SENSIBLES|TECNOLOGÍA ESPACIAL|USO DUAL|PERIFERIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6922,"idioma_id":4,"titulo":"POLYHYDROXYBUTYRATE-BASED NANOCOMPOSITES WITH CELLULOSE NANOCRYSTALS AND BACTERIAL CELLULOSE","resumen":"Polyhydroxybutyrate (PHB) films nanoreinforced with hydrolyzed cellulose nanocrystals (CNC) and bacterial cellulose (BC) were prepared by solvent casting. The influence of different cellulose nanoparticles content (2, 4 and 6 wt% of CNC and 2 wt% of BC) on the PHB properties was studied. CNC nanocomposites presented good dispersion of the nanocrystals, improving transparency, mechanical and barrier properties of the PHB films. On the other hand, reduced thermal stability and mechanical properties were yielded by BC addition due to the intrinsic lower degradation temperature and higher length of the BC nanofibrils compared to CNC. Nanocomposites performance variation is mainly caused by the marked difference in nanoparticles structure. It was demonstrated that PHB-CNC films exhibited higher performance enhancement without detrimental effect of the pristine PHB properties.","palabras_clave":"POLYHYDROXYBUTYRATE|NANOCELLULOSE|NANOCOMPOSITES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6923,"idioma_id":4,"titulo":"Evaluation of the infectivity and the persistence of Trichinella patagoniensis in muscle tissue of decomposing guinea pig (Cavia porcellus)","resumen":"Trichinella patagoniensis, a new species of Trichinella, is widespread in Argentina. The success of parasite transmission depends, among other factors, on the resistance of L1 larvae present in the muscle tissue (ML) of dead hosts undergoing the decomposition process in different environmental conditions. The aim of the present work was to study the infectivity of T. patagoniensis muscle larvae in Cavia porcellus and the capability of the parasite to survive in decomposed muscle tissue of guinea pigs subjected to different environmental conditions. Thirty-two female Ssi:AL guinea pigs were orally inoculated with 2000 ML of T. patagoniensis (ISS2311). All the animals were sacrificed 42 days post-infection. Twenty-six animals were eviscerated, and carcasses were placed on the surface of soil inside plastic boxes that were exposed to environmental conditions in the summer 2014?2015 and autumn of 2015 in Buenos Aires, Argentina. Carcasses from six animals were placed into a plastic box inside the refrigerator at a temperature of 4 °C. The muscle tissue samples from the carcasses were examined weekly for the presence of larvae, and the infectivity of recovered ML was tested in BALB\/c mice. Our results showed for the first time the ability of T. patagoniensis to complete its life cycle in guinea pigs, thus serving as a potential natural host. Also, larvae of T. patagoniensis remained infective in muscle tissue for several weeks while undergoing decomposition under different environmental conditions.","palabras_clave":"Trichinella patagoniensis |Persistence in decomposing muscle tissue |Infectivity|Cavia porcellus"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6937,"idioma_id":4,"titulo":"Actinobacteria: Current research and perspectives for bioremediation of pesticides and heavy metals","resumen":"Actinobacteria exhibit cosmopolitan distribution since their members are widely distributed in aquaticand terrestrial ecosystems. In the environment they play relevant ecological roles including recycling ofsubstances, degradation of complex polymers, and production of bioactive molecules. Biotechnologicalpotential of actinobacteria in the environment was demonstrated by their ability to remove organic andinorganic pollutants. This ability is the reason why actinobacteria have received special attention ascandidates for bioremediation, which has gained importance because of the widespread release ofcontaminants into the environment. Among organic contaminants, pesticides are widely used for pestcontrol, although the negative impact of these chemicals in the environmental balance is increasinglybecoming apparent. Similarly, the extensive application of heavy metals in industrial processes lead tohighly contaminated areas worldwide. Several studies focused in the use of actinobacteria for cleaningup the environment were performed in the last 15 years. Strategies such as bioaugmentation, biostimulation,cell immobilization, production of biosurfactants, design of de&#64257;ned mixed cultures and theuse of plant-microbe systems were developed to enhance the capabilities of actinobacteria in bioremediation.In this review, we compiled and discussed works focused in the study of different biore-mediation strategies using actinobacteria and how they contributed to the improvement of the alreadyexisting strategies. In addition, we discuss the importance of omic studies to elucidate mechanisms andregulations that bacteria use to cope with pollutant toxicity, since they are still little known in actinobacteria.A brief account of sources and harmful effects of pesticides and heavy metals is also given.","palabras_clave":"Actinobacteria|Bioremediation|Pesticides|Heavy metals|Environmental pollution|Co-contamination"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6949,"idioma_id":4,"titulo":"Assessment of liver slices for research on metabolic drug-drug interactions in cattle","resumen":"1.&#8194;Precision-cut liver slices (PCLS) from food-producing animals have not been extensively used to study xenobiotic metabolism, and thus information on this field of research is sparse. 2.&#8194;The aims of the present work were to further validate the technique of production and culture of bovine PCLS and to characterize the metabolic interaction between the anthelmintic albendazole (ABZ) and the flavin-monooxygenase (FMO) inhibitor methimazole (MTZ). 3.&#8194;Nine steers were used as donors. PCLS were produced and incubated under two methods: a dynamic organ culture (DOC) incubator and a well-plate (WP) system. 4.&#8194;Tissue viability, assessed through both structural and functional markers, was preserved throughout 12 h of incubation. ABZ was metabolized to its (+) and (-) albendazole sulfoxide stereoisomers (ABZSO) in bovine PCLS. The interaction between ABZ and MTZ resulted in a reduction (p < 0.001) in the rates of appearance of (+) ABZSO. Conversely, in presence of MTZ, the rates of appearance of (&#8722;) ABZSO increased under both systems (p < 0.05). 5.&#8194;Both culture systems were suitable for assessing the interaction between ABZ and MTZ. 6.&#8194;Overall, the results presented herein show that PCLS are a useful and reliable tool for short-term studies on metabolic drug?drug interactions in the bovine species.","palabras_clave":"LIVER|SLICES|METABOLIC|CATTLE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6969,"idioma_id":4,"titulo":"Notes on mildly distributive semilattices","resumen":"In this paper, we shall investigate the mildly distributive meet-semilattices by means of the study of their filters and Frink-ideals as well as applying the theory of annihilator. We recall some characterizations of the condition of mildly-distributivity and we give several new characterizations. We prove that the definition of strong free distributive extension, introduced by Hickman in 1984, it can be simplified and we show a correspondence between (prime) Frink-ideals of a mildly distributive semilattice and (prime) ideals of its strong free distributive extension.","palabras_clave":"semilattices|mildly-distributivity|Frink-ideals| free extension"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6986,"idioma_id":4,"titulo":"The targeting of starch binding domains from starch synthase III to the cell wall alters cell wall composition and properties","resumen":"The plant cell wall, which represents a major source of biomass for biofuel production, is composed of cellulose, hemicelluloses, pectins and lignin. A potential biotechnological target for improving the production of biofuels is the modification of plant cell walls. This modification is achieved via several strategies, including, among others, altering biosynthetic pathways and modifying the associations and structures of various cell wall components. In this study, we modified the cell wall of A. thaliana by targeting the starch-binding domains of A. thaliana starch synthase III to this structure. The resulting transgenic plants (E8-SDB123) showed an increased biomass, higher levels of both fermentable sugars and hydrolyzed cellulose and altered cell wall properties such as higher laxity and degradability, which are valuable characteristics for the second-generation biofuels industry. The increased biomass and degradability phenotype of E8-SBD123 plants could be explained by the putative cell-wall loosening effect of the in tandem starch binding domains. Based on these results, our approach represents a promising biotechnological tool for reducing of biomass recalcitrance and therefore, the need for pretreatments.","palabras_clave":"STARCH BINDING DOMAINS|CELL WALL|CELL EXTENSION|CELL WALL DIGESTIBILITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":6990,"idioma_id":4,"titulo":"Clinical significance of an alloantibody against the Kell blood group glycoprotein","resumen":"Background: Kell null (K0) individuals can produce anti-Ku, an antibody against many epitopes in the Kell glycoprotein, after transfusion and\/or pregnancy. Since sensitized K0 patients are rare, little is known about anti-Ku clinical relevance and in particular about its association to Hemolytic Disease of the Fetus and Newborn. Case report: This work describes a case of neonatal hyperbilirubinemia due to immune mediated erythrocyte destruction by an alloantibody directed against the Kell glycoprotein. Serologic and molecular approaches identified an anti-Ku alloantibody in maternal serum. A homozygous IVS3+1g>a point mutation (KEL*02N.06 allele) was found to be responsible for the lack of Kell antigens expression in the mother?s red blood cell and subsequent alloimmunization after a previous pregnancy. Even though in most cases Kell antibodies are clinically severe and may cause suppression of erythropoiesis, in our case the newborn had a moderate anemia and hyperbilirubinemia that was successfully treated with phototherapy without requiring exchange transfusion. Serological and molecular studies performed in the proband?s family members allowed us to provide them with proper counseling regarding alloimmunization after transfusion and\/or pregnancy. Conclusions: This case enlarges the understanding of the clinical significance of alloantibodies against Kell blood group antigens.","palabras_clave":"Anti-Ku ALLOANTIBODY|ALLOIMMUNIZATIO|KELL BLOOD GROUP SYSTEM"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7002,"idioma_id":4,"titulo":"Cefazolin pharmacokinetics in cats under surgical conditions","resumen":"Objectives The aim of this study was to determine the plasma pharmacokinetic profile, tissue concentrations andurine elimination of cefazolin in cats under surgical conditions after a single intravenous dose of 20 mg\/kg.Methods Intravenous cefazolin (20 mg\/kg) was administered to nine young mixed-breed cats 30 mins beforethey underwent surgical procedures (ovariectomy or orchiectomy). After antibiotic administration, samples fromblood, some tissues and urine were taken. Cefazolin concentrations were determined in all biological matrices andpharmacokinetic parameters were estimated.Results Initial plasma concentrations were high (Cp(0), 134.80 ± 40.54 &#956;g\/ml), with fast and moderately widedistribution (T½(d) 0.16 ± 0.15 h; V(d[ss]) 0.29 ± 0.10 l\/kg) and rapid elimination (ClB, 0.21 ± 0.06 l\/h\/kg; t½, 1.18± 0.27 h; mean residence time, 1.42 ± 0.36 h). Thirty to 60 mins after intravenous administration, cefazolintissue concentrations ranged from 9.24 &#956;g\/ml (subcutaneous tissue) to 26.44 &#956;g\/ml (ovary). The tissue\/plasmaconcentration ratio ranged from 0.18 (muscle) to 0.58 (ovary). Cefazolin urine concentrations were high with 84.2%of the administered dose being eliminated in the first 6 h postadministration.Conclusions and relevance Cefazolin plasma concentrations remained above a minimum inhibitory concentrationof &#10877;2 &#956;g\/ml up to 4 h in all the studied cats. This suggests that a single intravenous dose of 20 mg\/kg cefazolinwould be adequate for perioperative prophylactic use in cats.","palabras_clave":"CEFAZOLIN|FELINE|PHARMACOKINETICS|SURGERY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7010,"idioma_id":5,"titulo":"Gubernamentalidad y poder pastoral","resumen":"En sus trabajos de fines de la década de 1970 Michel Foucault abordó lanoción de gubernamentalidad para dar cuenta del funcionamiento del gobiernode los hombres. En su genealogía de estas tecnologías de gobierno encuentraun antecedente remoto en el poder pastoral y afirma que el pastorado es ajenoal pensamiento político de la Grecia clásica. En este trabajo desarrollo algunosproblemas en la presentación que realiza de la obra de Platón. Foucault estudiala aparición del poder pastoral en las obras políticas de Platón, en particular enPolítico, y afirma que allí se rechaza al pastor como clave para explicar la actividad de gobierno, pero creo que sus argumentos no alcanzan para realizar esta afirmación.","palabras_clave":"GUBERNAMENTALIDAD|PODER PASTORAL |TEJEDOR|POLÍTICO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7015,"idioma_id":4,"titulo":"The pleiotropic transcriptional regulator NlpR contributes to the modulation of nitrogen metabolism, lipogenesis and triacylglycerol accumulation in oleaginous rhodococci","resumen":"The regulatory mechanisms involved in lipogenesis and triacylglycerol (TAG) accumulation are largely unknown in oleaginous rhodococci. In this study we identified a regulatory protein (here called NlpR: Nitrogen lipid Regulator), which contributes to the modulation of nitrogen metabolism, lipogenesis and triacylglycerol accumulation in oleaginous rhodococci. Under nitrogen deprivation conditions, in which TAG accumulation is stimulated, the nlpR gene was significantly upregulated, whereas a significant decrease of its expression and TAG accumulation occurred when cerulenin was added. The nlpR disruption negatively affected the nitrate\/nitrite reduction as well as lipid biosynthesis under nitrogen-limiting conditions. In contrast, its overexpression increased TAG production during cultivation of cells in nitrogen-rich media. A putative ?NlpR-binding motif? upstream of several genes related to nitrogen and lipid metabolisms was found. The nlpR disruption in RHA1 strain led to a reduced transcription of genes involved in nitrate\/nitrite assimilation, as well as in fatty acid and TAG biosynthesis. Purified NlpR was able to bind to narK, nirD, fasI, plsC and atf3 promoter regions. We suggest that NlpR acts as a pleiotropic transcriptional regulator by activating of nitrate\/nitrite assimilation genes and others genes involved in fatty acid and TAG biosynthesis, in response to nitrogen deprivation.","palabras_clave":"RHODOCOCCUS|TRIACYLGLYCEROLS|REGULATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7023,"idioma_id":4,"titulo":"Physic-mechanical behavior of concretes exposed to high temperatures and different cooling systems","resumen":"Over their lifetime, concrete structures can suffer from different pathologies, one of them is exposure to high temperatures, which diminishes their load-bearing capacity. This study describes how different concrete types were exposed to high temperatures. To simulate fire extinction, where the temperature of the overheated concrete descends suddenly, different cooling systems were applied: slowly cooling in the open air and fast cooling by spraying different water volumes. Several physical?mechanical characteristics were analyzed such as compressive strength, splitting tensile strength, porosity, capillary suction, and carbonation depth. Ultrasound nondestructive tests were conducted to quantify deterioration. A petrographic study using a stereomicroscope and microscopy of polarization was performed on thin sections to evaluate aggregate composition and concrete characteristics, focusing on interface areas. Physical and mechanical properties were affected by the increase in temperature, with damage worsening through the appearance of cracks and microcracks when water is used as a cooling system.KEYWORDS: concrete, nondestructive tests, petrography, temperature","palabras_clave":"Concrete|Temperature|Non-destructive tests|Petrography"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7041,"idioma_id":4,"titulo":"The protein phosphatase 2A catalytic subunit StPP2Ac2b acts as a positive regulator of tuberization induction in Solanum tuberosum L.","resumen":"The serine\/threonine protein phosphatasestype 2A (PP2A) are implicated in several physiologicalprocesses in plants, playing important roles in hormoneresponses. In cultivated potato (Solanum tuberosum), sixPP2A catalytic subunits (StPP2Ac) were identiied. ThePP2Ac of the subfamily I (StPP2Ac1, 2a and 2b) weresuggested to be involved in the tuberization signaling inleaves, where the environmental and hormonal signalsare perceived and integrated. The aim of this study wasto investigate the role of PP2A in the tuberization inductionin stolons. We selected one of the catalytic subunitsof the subfamily I, StPP2Ac2b, to develop transgenicplants overexpressing this gene (StPP2Ac2b-OE). Stolonsfrom StPP2Ac2b-OE plants show higher tuber inductionrates in  vitro, as compared to wild type stolons, with nodiferences in the number of tubers obtained at the end ofthe process. This efect is accompanied by higher expressionlevels of the gibberellic acid (GA) catabolic enzymeStGA2ox1. GA up-regulates StPP2Ac2b expression instolons, possibly as part of the feedback system by whichthe hormone regulates its own level. Sucrose, a tuber-promotingfactor in  vitro, increases StPP2Ac2b expression.We conclude that StPP2Ac2b acts in stolons as a positiveregulator tuber induction, integrating diferent tuberization-relatedsignals mainly though the modulation of GAmetabolism.","palabras_clave":"PP2A|Phosphatase|Potato|Solanum tuberosum |tuberization"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7051,"idioma_id":4,"titulo":"Characterization of biomaterials commonly used in dentistry for bone augmentation by X-ray and electron techniques","resumen":"Hydroxyapatite (HA), beta-tricalcium phosphate and bioactive glasses are commonly used as reabsorbable biomaterials, mainly in orthopaedics and dentistry. The performance of each material depends on many factors, in particular, on their chemical and phase composition, microstructure, granule size and pore volume. For this reason, it is important to have a full characterization that allows correlating these properties with the material biological behaviour. In this work, three commercial samples of materials currently used in dentistry as bone substitutes were characterized. Granules corresponding to bovine and synthetic HA and bioactive glass 45S5 type were studied by scanning electron microscopy, conventional and synchrotron radiation X-ray diffraction and X-ray fluorescence. The specific surface area was also obtained by the Brunauer, Emmett and Teller method. We observed that Ca\/P molar ratios for both HAs are higher than the value corresponding to the stoichiometric HA. The coherent domain obtained for the bovine HA is larger along the c axis crystal direction, and it is around 15 times lower than the value corresponding to the synthetic HA. The specific surface area for the bovine HA is one of the highest values reported in literature. Low amounts of crystalline CaO were observed only for the synthetic HA sample. Crystalline combeite and wollastonite were detected for the bioactive glass sample and quantified by using rutile as internal standard. The relation between the physico-chemical characterization performed in this work and the potential biological response of the materials is discussed in terms of the information available in literature. Copyright © 2016 John Wiley & Sons, Ltd.","palabras_clave":"BIOMATERIALS|HYDROXYAPATITE|DENTISTRY|GLASSES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7063,"idioma_id":4,"titulo":"Arithmetics and combinatorics of tropical Severi varieties of univariate polynomials","resumen":"We give a description of the tropical variety of univariate polynomials ofdegree n having two double roots. As a set, it is given as the union of threetypes of maximal cones of dimension n-1, where only cones of two of these typesare cones of the secondary fan of {0,...,n}. Through Kapranov´s theorem, thisgoal is achieved by a careful study of the possible valuations of theelementary symmetric functions of the roots of a polynomial with two doubleroot. Despite its apparent simplicity, the computation of the tropical Severivariety has both combinatorial and arithmetic ingredients.","palabras_clave":"Severi variety|Tropicalization|Discriminant|Valuation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7075,"idioma_id":4,"titulo":"A discriminatively trained fully connected conditional random field model for blood vessel segmentation in fundus images","resumen":"Objective: In this work, we present an extensivedescription and evaluation of our method for blood vesselsegmentation in fundus images based on a discriminativelytrained, fully connected conditional random field model. Methods:Standard segmentation priors such as a Potts model or totalvariation usually fail when dealing with thin and elongatedstructures. We overcome this difficulty by using a conditionalrandom field model with more expressive potentials, takingadvantage of recent results enabling inference of fully connectedmodels almost in real-time. Parameters of the method are learnedautomatically using a structured output support vector machine,a supervised technique widely used for structured predictionin a number of machine learning applications. Results: Ourmethod, trained with state of the art features, is evaluatedboth quantitatively and qualitatively on four publicly availabledata sets: DRIVE, STARE, CHASEDB1 and HRF. Additionally,a quantitative comparison with respect to other strategies isincluded. Conclusion: The experimental results show that thisapproach outperforms other techniques when evaluated in termsof sensitivity, F1-score, G-mean and Matthews correlation coefficient. Additionally, it was observed that the fully connectedmodel is able to better distinguish the desired structures than thelocal neighborhood based approach. Significance: Results suggestthat this method is suitable for the task of segmenting elongatedstructures, a feature that can be exploited to contribute withother medical and biological applications.","palabras_clave":"Blood vessel segmentation|Fundus imaging|Conditional random fields|Structured output SVM"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7106,"idioma_id":4,"titulo":"Incorporation of Okara into Gluten-Free Cookies with High Quality and Nutritional Value","resumen":"Soy products are a source of protein relatively inexpensive and recognized for their high nutritional value and functional properties.Okara is a byproduct from soy milk production. Gluten-free cookies have been developed using okara and commercial maniocflour. Four formulations were developed with different proportions of okara: 50%; 30%; 15%; and 0%. Physicochemical, physicalproperties, sensory analysis, and nutritional studieswere performed.The use of inulin as partial replacement of sugar was evaluated.The incorporation of okara increased protein and fiber content. Furthermore, the hardness of cookies increased while the indexof whiteness decreased. From the sensory evaluation, it could be concluded that the cookies presented a great acceptability. Thecookies developed in this study have functional characteristics, providing added value to a waste product; furthermore the productswere suitable for celiacs with acceptable quality and improved nutrition value.","palabras_clave":"okara|gluten-free cookie| dietary fiber,.| sugar substitutes."},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7110,"idioma_id":5,"titulo":"Eficiencia de uso del nitrógeno por forrajera s abonadas con estiércol de bovinos lecheros en la región pampeana. Argentina","resumen":"La intensificación de los sistemas ganaderos con el consiguiente aumento de la carga animal incrementa cantidad de estiércol que puede ser reutilizado como una fuente de nutrientes para cultivos forrajeros. Elpropósito del trabajo fue recopilar y comparar los resultados obtenidos de a) calidad de estiércol en diferenteszonas de producción lechera de la Argentina y b) resultados de ensayos realizados en dos ambientes climáticos diferentes sobre la eficiencia de utilización del nitrógeno (N) del estiércol de bovinos lecheros como fertilizante de recursos forrajeros y cultivos. Se sistematizó la información analítica (materia seca (%MS), nitrógeno (%N) y fósforo (%P)) de 36 muestras de estiércol proveniente de pilas de almacenamiento o de tratamiento por separador de sólidos con igual metodología en el norte de Buenos Aires (BA) y Centro de Santa Fe (SF). Se recopiló información de suelo, clima, calidad del estiércol, dosis y estrategia de aplicación y de productividad en 13 ensayos, cinco realizados en BA y ocho en SF. Los recursos forrajeros y cultivos fueron: alfalfa, avena, maíz, moha, raigrás anual, pasturas polifíticas, sorgo de pastoreo y para silaje y trigo. Para comparar los resultados se utilizaron dos indicadores de eficiencia de uso del N, el de N total (EUN) y del N disponible para las plantas (EU-NDP), con respecto a la producción del testigo, expresados como kg MS producida·(kgN o kgNDP aplicado)-1, respectivamente.El NDP se obtiene de información internacional para estimar la mineralización esperada, a priori, durante el año de aplicación. La calidad del estiércol presenta características variables en las zonas estudiadas, coincidentes con estudios internacionales (%MS de 16,3 a 56,0, %N de 2,9 a 19 y %P de 0,1 a 0,8), atribuidas a diferente manejo del agua, tipo de separador y alimentación. Los valores de EUN fueron desde 2,3 hasta 51,8 kg MS.Kg N-1 y de EU-NDP desde 4 hasta 81,8 kg MS·kgNDP-1, según cultivo y ambientes edafo-climáticos. Las variables temperatura y precipitaciones fueron las que más incidieron en las EUN, respecto de condiciones edáficas y del estiércol, tales como su acondicionamiento previo, momento y división de la dosis total aplicada. Es decir, con temperaturas templadas y buena humedad se esperan mejores condiciones de mineralización que favorezcan la eficiencia de uso de estos recursos orgánicos, que requieren de condiciones muy específicas para que sus nutrientes estén disponibles para los cultivos. En distintas zonas de la región pampeana se podría utilizar estiércol vacuno como fuente nitrogenada para favorecer la acumulación de biomasa aérea, a partir de su reuso.","palabras_clave":"Reciclado efluentes ganaderos|Abonado organico|Produccion animal y ambiente|Efluentes ganaderos"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7127,"idioma_id":4,"titulo":"Strategies for increasing reproductive efficiency in a commercial embryo transfer program with high performance donor mares under training","resumen":"Exercise stress has a negative impact on embryo transfer efficiency (ET). For example, a 34% embryo recovery rate, 43% incidence of poor quality embryos, and a 29% pregnancy rate after transfer have been reported. Administration of nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce the inflammatory response produced after nonsurgical embryo transfer. In addition, progesterone supplementation is commonly administered to some recipient mares to improve uterine conditions before the transfer and to ensure adequate progestational support compatible with pregnancy. The aim of the study was to evaluate embryo recovery rates using BioRelease deslorelin versus hCG and to increase posttransfer pregnancy rates by jointly administering BioRelease progesterone and a NSAID (flunixin or meloxicam) to recipient mares. Seventeen upper-level showjumping mares stabled and in daily training were used as embryo donors. To induce ovulation, 1-mg IM BioRelease deslorelin (BioRelease Technologies, Lexington, KY) was injected in treated cycles (n = 66), or 2500-IU hCG IV (Ovusyn, Syntex, Buenos Aires, Argentina) was given in control cycles (n = 79) when a &#8805;35 mm follicle was present. Artificial insemination with extended fresh semen (at least 500 × 106 progressively motile sperm) was carried out in both groups immediately after injecting the ovulation induction agent. Day 8 embryos were recovered and nonsurgically transferred using a speculum and a cervical traction forceps. Recipient mares (n = 73) were randomly assigned to one of three groups: Group A received a single injection of 1.5-g IM BioRelease progesterone (Progesterone LA 300, BioRelease Technologies) and 3 IV injections of 0.5 g of flunixin meglumine (Flunix Deltavet, Argentina), one injection administered the day of the transfer and one on each of the next two successive days. Group B received 1.5-g IM BioRelease progesterone and a single dose of 1.5-g IM BioRelease meloxicam (Meloxicam LA, BioRelease Technologies) at the moment of embryo transfer. Group C did not receive any treatment. Pregnancy diagnosis was carried out 7 days after transfer. Results were analyzed using comparisons of proportions. More embryos were recovered per cycle (13% increase) when donor mares in training were induced to ovulate with BioRelease deslorelin (60.6%; 40\/66) than with hCG (46.8%; 37 of 79; P <.05). Although both recipient groups given NSAIDs in combination with BioRelease progesterone numerically had higher pregnancy rates (A: 70.8%; 17\/24 and B: 75%; 15\/20) compared with nontreated control recipients (47.1%; 33\/70), pregnancy rates were significantly higher only in recipients given LA meloxicam treatment at the time of transfer (P <.05). The LA meloxicam is released over a 72-hour period making it more practical to use as it requires a single IM injection versus the 3 IV flunixin meglumine injections. Thus, to minimize the effects of exercise stress on ET efficiency, a combination of BioRelease deslorelin to induce ovulation in donors and BioRelease progesterone and LA meloxicam in recipients at the time of transfer may offer an interesting alternative for improving results in commercial ET programs.","palabras_clave":"Embryo transfer|exercise|stress|NSAID|progesterone|desloreline|hCG"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7143,"idioma_id":4,"titulo":"Novel 2- arylazoimidazole derivatives as inhibitors of Trypanosoma cruzi proliferation: synthesis and evaluation of their biological activity","resumen":"In this work, the synthesis of a series of 2-arylazoimidazole derivatives 6-20 has been achieved through the reaction of imidazole with aryldiazonium salts, followed by ultrasound-assisted alkylation. This approach has important advantages including higher yield, shorter reaction times and milder reaction conditions. The structures of the compounds obtained were determined by MS, IR; and 1H and 13C NMR. The anti-Trypanosoma cruzi activity of the 15 compounds obtained was evaluated. Two compounds with piperidino substituents in the carboxamide moiety proved to be effective inhibitors of epimastigote proliferation, obtaining inhibition values comparable to those achieved with the reference drug Benznidazole. Besides, these compounds displayed low cytotoxicity on mammalian cells. In&nbsp;vivo, both compounds protected mice against a challenge with a lethal Trypanosoma cruzi strain. These results allow us to propose 2-arylazoimidazoles as lead compounds for the design of novel drugs to treat Chagas´ disease.","palabras_clave":"2-arylazoimidazoles|ultrasound-assisted alkylation|Chagas disease|biological activity"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7151,"idioma_id":5,"titulo":"Jóvenes y Educación Superior en Argentina. Evolución y tendencias","resumen":"En lo que va de las últimas décadas el Sistema Educativo Argentino registró mutaciones de magnitud en todos los  niveles que comprende la enseñanza formal. Tanto la evolución de la población escolarizada como los aspectos políticos institucionales y los desafíos de mayor inclusión, son materia de discusión continua. Este texto está orientado a analizar la situación educativa de la población de jóvenes argentinos de 15 a 29 años de edad, en los últimos años. Para eso, se revisaron datos del sistema educativo y su expansión en términos de la asistencia y composición, prestando particular atención a la información sobre la educación superior. Una de las conclusiones relevantes del estudio ratifica una mayor participación de los jóvenes en el sistema educativo y más posibilidad de acceso a niveles educativos superiores para el periodo bajo análisis. Es decir, el nivel socio económico persiste como un factor de peso en las trayectorias educativas de las generaciones jóvenes mostrando debilidades y exiguos avances que dan cuenta de lo recorrido y lo faltante.","palabras_clave":"Sistema Educativo|Jóvenes|Educación Superior"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7157,"idioma_id":4,"titulo":"Assessing environmental health using ecological indices for soft bottom in sewage-affected rocky shores: The case of the largest seaside resort of SW Atlantic","resumen":"Efficient indices would reflect the differences between impacted and no-impacted sites, leading to significant variations at the contamination spatial scale. We evaluate the spatial-temporal variability of 3 ecological indices (AMBI, M-AMBI, BENTIX) in response to the distinct levels of sewage contamination. The indices were evaluated in two different ways: including Brachidontes rodriguezii (IBR) and excluding Brachidontes rodriguezii (EBR). The fact that mussel beds created a secondary infaunal habitat allows us to test these indices for soft-bottoms in areas with rocky-bottoms. Theses indices increased their effectiveness and the level of agreement when they were calculated without B. rodriguezii. BENTIX and M-AMBI produced under and overestimations of the ecological status of the studied sites. AMBI(EBR) seems to be better suited for environmental quality assessment in the study area. This reduces the processing time of samples so the AMBI(EBR) could be used as a robust management tool for monitoring-programs in areas with hard-substrate.","palabras_clave":"INDICES AMBI, M-AMBI, BENTIX|URBAN EFFLUENTS|INTERMAREAL ROCOSO|MAR DEL PLATA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7161,"idioma_id":4,"titulo":"Formation, microstructure and properties of aluminum borate ceramics obtained from alumina and boric acid","resumen":"The formation of aluminum borates (Al18B4O33 and Al4B2O9) from alumina and boron oxide occurs between 600 and 800 °C. These materials have refractory properties and corrosion resistance. The objective of this work is to develop materials from the Al2O3-B2O3 system, employing alumina and boric acid as starting powders, to study the critical processing variables and describe the developed microstructure and properties. Three formulations (13, 19.5 and 26 wt% B2O3) were studied. In order to confirm the formation of borates, the differential thermal analysis and thermogravimetric analysis were carried out. Afterwards, uniaxially pressed disc-shaped specimens were fired at four temperatures above the formation temperature. The textural properties of the ceramics were evaluated by the immersion method, this permit to evaluate the sintering processes. Then the degree of borate formation was confirmed by X-ray diffraction. Finally, the developed microstructures were characterized by scanning electron microscopy, and the diametral compression behavior was evaluated. A series of porous (&#8776;50%) refractory materials from the Al2O3-B2O3 system were developed. The processing strategy resulted in materials with Al18B4O33 as the main crystalline phase. Needle grains with diameters between 0.2 and 1 µm and an aspect ratio over 20:1 were obtained. Thus, based on the information gathered from our research, aluminum borate ceramic materials can be designed for structural, insulating or filtering applications employing only alumina and boric acid as boron oxide source.","palabras_clave":"Porous ceramics|Aluminum borate|Processing|Characterization"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7187,"idioma_id":4,"titulo":"High nutrient retention in chronically nutrient-rich lowland streams","resumen":"Nutrient retention has been studied intensively in streams, but some mechanisms and processes are not yet entirely understood, especially in open-canopy streams. We evaluated PO4, as soluble reactive P (SRP), and NH4 uptake in 2 chronically enriched Pampean streams with different macrophytic abundance. We performed short-term nutrient additions to quantify SRP and NH4 1 uptake metrics throughout the year, and we investigated which hydrological and biological factors influenced nutrient uptake. The results showed that SRP and NH4 uptakes were high in relation to pristine and impaired streams elsewhere, and they did not saturate despite elevated background nutrient levels. NH4 areal uptake rate fit in a 1st-order uptake model, but an exponential model described the  relationship between SRP areal uptake rate and SRP concentration. Consistent with this finding, SRP uptake velocity tended to increase linearly, and SRP uptake length decreased linearly with SRP concentration. The analysis of factors influencing uptake metrics suggested that SRP uptake mainly depended on heterotrophic demand, whereas NH4 uptake was enhanced under more autotrophic conditions. Our results showed that nutrient uptake metrics of enriched Pampean streams were similar to those observed in streams with low nutrient levels.","palabras_clave":"captación de nitratos|captación de amonio|macrófitas|biofilm"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7188,"idioma_id":4,"titulo":"Heat stress induces ferroptosis-like cell death in plants","resumen":"In plants, regulated cell death (RCD) plays critical roles during development and is essential for plant-specifi responses to abiotic and biotic stresses. Ferroptosis is an iron-dependent, oxidative, nonapoptotic form of cell death recently described in animal cells. In animal cells, this process can be triggered by depletion of glutathione (GSH) and accumulation of lipid reactive oxygen species (ROS). We investigated whether a similar process could be relevant to cell death in plants. Remarkably, heat shock (HS)?induced RCD, but not reproductive or vascular development, was found to involve a ferroptosis-like cell death process. In root cells, HS triggered an iron-dependent cell death pathway that was characterized by depletion of GSH and ascorbic acid and accumulation of cytosolic and lipid ROS. These results suggest a physiological role for this lethal pathway in response to heat stress in Arabidopsis thaliana. The similarity of ferroptosis in animal cells and ferroptosis-like death in plants suggests that oxidative, iron-dependent cell death programs may beevolutionarily ancient.","palabras_clave":"FERROPTOSIS|CELL DEATH|HEAT STRESS|KOD|IRON|PLANT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7191,"idioma_id":5,"titulo":"CONFIGURACIÓN ESPACIO ? TEMPORAL DE LAS VARIABLES AMBIENTALES EN RELACIÓN A LOS RIESGOS NATURALES EN POTRERILLOS, MENDOZA.","resumen":"Las villas cordilleranas de Potrerillos, al suroeste de la zona metropolitana de Mendoza, tienden a alojar y sostener procesos geológicos de orden interno y externos relacionados a eventos sísmicos y aluvionales, entre otros. La creciente y descontrolada urbanización que esta zona turística está teniendo, hace que gran parte de la población se desplace hacia áreas de importantes pendientes, generadoras de fenómenos relacionados con eventos pluviométricos estivales donde se activan procesos de remoción en masa, que en parte son activados por acontecimientos sísmicos, comunes en el área. Estos procesos junto a otros de menor orden, pero no así menos importantes, colocan a un núcleo de habitantes en Riesgo Geológico. Se presentan en esta oportunidad, los trabajos realizados tendientes a la elaboración de cartografía de detalle para establecer planes de mitigación, zonificación y contingencia adecuados en la zona. Se realizaron estudios tomando información de sensores OLI, ETM+ y TM del programa LANDSAT, de los programas ASTER y  SENTINEL2 a los efectos de   establecer comparaciones multitemporales para determinar vectores de crecimiento urbano. Contemporáneamente a esto, se realizaron procesamientos digitales para establecer diferencias estratigráficas, topográficas, de orientación, actitud y de anisotropías propias de deformaciones estructurales que pudieran marcar parámetros físicos para determinar zonas de peligrosidad geológica e hidrológica activa. Dentro de estos análisis digitales se incluyeron trabajos con clasificación supervisada (maximum likelihood), por árbol de decisiones (utilizando modelos digitales de elevación a partir de datos propios), density slice, componentes principales y decorrelation stretch. Los resultados aportaron una salida cartográfica RASTER de detalle, la cual, complementada con trabajos de campo, permitieron resumir información para establecer exitosamente zonas de potencial peligro sísmico e hidrológico. Se presentan en esta oportunidad los gráficos resultantes.","palabras_clave":"peligro|riesgos|geologia|Potrerillos"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7198,"idioma_id":4,"titulo":"Food residues as indicators of processed plants in hunter-gatherers pottery from La Pampa (Argentina)","resumen":"This paper presents the results of archaeobotanical studies of plant microremains adhered to the surfaces of charred cooking-pot residues, corresponding to a context of hunter-gatherer societies in semiarid environments (Western Pampa, Argentina). Microparticles (starch granules, phytoliths, micro-charcoal, ochre-coloured organic matter and fungal remains) were identified, and the taphonomic factors that affected the plant microremains were described. Results indicate the use of ceramic containers for processing wild plants (Poaceae and Prosopis sp.), cultivated plants (Zea mays L.) and other ingredients. This study suggests the importance of plants in the diet of Pampean hunter-gatherers and the effective use of ceramic containers for processing and preparation of these resources.","palabras_clave":"HUNTER GATHERER|WESTERN PAMPAS OF ARGENTINA|POTTERY|RESIDUE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7199,"idioma_id":4,"titulo":"Marginal integration M-estimators for additive models","resumen":"Additive regression models have a long history in multivariate nonparametricregression. They provide a model in which the regression function isdecomposed as a sum of functions, each of them depending only on a single explanatory variable. The advantage of additive models over general non-parametric regression models is that they allow to obtain estimators converging at the optimal univariate rate avoiding the so-called curse of dimensionality. Beyond backfitting, marginal integration is a common procedure to estimate each component in additive models. In this paper, we propose a robust estimator of the additive components which combines local polynomials on the component to be estimated with the marginal integration procedure. The proposed estimators are consistent and asymptotically normally distributed. A simulation study allows to show the advantage of the proposal over the classical one when outliers are present in the responses, leading to estimators with good robustness and efficiency properties.","palabras_clave":"ADDITIVE MODELS|LOCAL M-ESTIMATORS|KERNEL WEIGHTS|MARGINAL INTEGRATION|ROBUSTNESS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7206,"idioma_id":5,"titulo":"Groeber y los invertebrados fósiles del Miembro La Tosca, Cretácico Inferior de la Cuenca Neuquina: una historia de controversias paleontológicas","resumen":"La presente contribución describe el recorrido histórico del estudio de los invertebrados fósiles del Miembro La Tosca (Formación Huitrín), en base a una exhaustiva revisión bibliográfica y a nuevos datos paleontológicos de campañas recientes a la Sierra de la Cara Cura y Ranquil del Norte en Mendoza, para finalmente arribar al estado actual del conocimiento sobre la temática. Pablo Groeber visitó por primera vez la región de la Sierra de la Cara Cura entre los años 1914 y 1917 y es allí donde comienza la historia de los invertebrados de la unidad, con la colección de los primeros gastrópodos fósiles. Estos materiales fueron legados a R. Wichmann y M. Doello Jurado para su estudio taxonómico y por un error inicial en la procedencia de un ejemplar comenzaron las controversias acerca de las afinidades marinas o continentales de la fauna del Tosquense. Es en dicha región donde Groeber también describe los depósitos del ?Yeso de Transición? ubicados entre las facies marinas del Neocomiano y las facies continentales suprayacentes aludiendo a un pasaje paulatino del régimen puramente marino al puramente terrestre. Las controversias paleontológicas continuaron con errores en la determinación de bivalvos, gastrópodos y serpúlidos que en parte fueron adjudicados a taxones dulceacuícolas tales como conchóstracos, algas charáceas y bivalvos unionoideos. Estos errores taxonómicos derivaron en errores de interpretación paleoambiental. Charles E. Weaver marcó también un hito importante dado que fue el primero en describir bivalvos tosquenses, pero no habiendo tenido en cuenta las publicaciones previas de Groeber los asignó al tope de la Formación Agrio. Los nuevos datos paleontológicos aquí aportados incluyen el primer registro de trigonias pertenecientes a Rutitrigonia sp. y fragmentos de briozoarios cyclostomados, lo cual reafirma la filiación marina de la fauna de invertebrados del Tosquense. Asimismo se describen dos taxones de gastrópodos,  Paleoanculosa macrochilinoides (Doello Jurado) y Provalvata? sp., y se describen pavimentos de serpúlidos pertenecientes a Parsimonia laevis Goldfuss. La asociación de invertebrados fósiles bentónicos del Miembro La Tosca en su conjunto se caracteriza por tener baja diversidad, baja equitatividad, pequeño tamaño corporal y conchillas relativamente delgadas en comparación con las faunas de invertebrados de la subyacente Formación Agrio lo cual indica un ambiente marino marginal con estrés ambiental posiblemente por cambios en la salinidad.","palabras_clave":"GROEBER|LA TOSCA|CRETACICO INFERIOR|NEUQUEN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7214,"idioma_id":4,"titulo":"Lactic Acid Bacteria as Cell Factories for the Generation of Bioactive Peptides","resumen":"Thereis a growing interest in the incorporation of functional foods in the dailydiet to achieve health promotion and disease risk reduction. Numerous studieshave focused on the production of biologically active peptides asnutraceuticals and functional food ingredients due to their health benefits.These short peptides, displaying antihypertensive, antioxidant, mineralbinding, immunomodulatory and antimicrobial activities are hidden in a latentstate within the primary sequences of food proteins requiring enzymaticproteolysis for their release. While microbial fermentation is one of the majorand economically most convenient processes used to generate bioactive peptides,lactic acid bacteria (LAB) are widely used as starter cultures for theproduction of diverse fermented foods. This article reviews the current knowledgeon LAB as cell factories for the production of bioactive peptides from avariety ...","palabras_clave":"LACTIC ACID BACTERIA|PROTEINASE|BIOACTIVE PEPTIDES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7216,"idioma_id":4,"titulo":"Intestinal multidrug resistance-associated protein 2 is down-regulated in fructose-fed rats","resumen":"Expression and activity of jejunal multidrug resistance-associated protein 2 (Mrp2) and glutathione-S-transferase (GST) were examined in fructose fed Wistar rats, an experimental model of metabolic syndrome. Animals were fed on (a) control diet or (b) control diet plus 10% w\/vol fructose in the drinking water. Mrp2 and the &#945; class of GST proteins as well as their corresponding mRNAs were decreased, suggesting a transcriptional regulation by fructose. Confocal microscopy studies reaffirmed down-regulation of Mrp2. Everted intestinal sacs were incubated with 1-chloro-2,4-dinitrobenzene in the mucosal compartment, and the glutathione-conjugated derivative, dinitrophenyl- S-glutathione (DNP-SG; model Mrp2 substrate), was measured in the same compartment to estimate Mrp2 activity. Excretion of DNP-SG was substantially decreased by fructose treatment, consistent with simultaneous down-regulation of Mrp2 and GST. In addition, the effect of fructose on intestinal barrier function exerted by Mrp2 was evaluated in vivo using valsartan, a recognized Mrp2 substrate of therapeutic use. After intraduodenal administration as a bolus, intestinal absorption of valsartan was increased in fructose-drinking animals. Fructose administration also induced oxidative stress in intestinal tissue as demonstrated by significant increases of intestinal lipid peroxidation end products and activity of the antioxidant enzyme superoxide dismutase, by a decreased GSH\/GSSG ratio. Moreover, fructose treatment conduced to increased intestinal levels of the proinflammatory cytokines IL-&#946;1 and IL-6. Collectively, our results demonstrate that metabolic syndrome-like conditions, induced by a fructose-rich diet, result in down-regulation of intestinal Mrp2 expression and activity and consequently in an impairment of its barrier function","palabras_clave":"mrp2|frusctose|intestine"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7219,"idioma_id":4,"titulo":"Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells","resumen":"Tamoxifen is a standard endocrine therapy for estrogen receptor positive breast cancer patients. Despite its success, development of resistance mechanisms is still a serious clinical problem. Deregulation of survival signaling pathways play a key role in tamoxifen resistance, being upregulation of Rac1-PAK1 signaling pathway one of the most important. Here, we report the development of the breast cancer cell model MCF7::C1199 having Rac1 enhanced activity with the aim of evaluating the role of Rac1 in acquired endocrine resistance. These cells not only showed distinctive features of Rac1-regulated process as increased migration and proliferation rates, but also showed that upregulation of Rac1 activity triggered a hormonal-independent and tamoxifen resistant phenotype. We also demonstrated that PAK1 activity increases in response to Tamoxifen, increasing phosphorylation levels of estrogen receptor at Ser305, a key phosphorylation site involved in tamoxifen resistance. Finally, we evaluated the effect of 1A-116, a specific Rac1 inhibitor developed by our group, in tamoxifen-resistant cells. 1A-116 effectively restored tamoxifen anti-proliferative effects, switched off PAK1 activity and decreased estrogen receptor phospho-Ser305 levels. Since combination schemes of novel targeted agents with endocrine therapy could be potential new strategies to restore tamoxifen sensibility, these results show that inhibition of Rac1-PAK1 signaling pathway may provides benefits to revert resistance mechanisms in endocrine therapies.","palabras_clave":"SMALL GTPASA|PROTEIN KINASA|ESTROGEN RECEPTOR|HORMONE-INDEPENDENCE|BREAST CANCER"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7220,"idioma_id":4,"titulo":"Evidence of VTA and LC control of protein synthesis required for the behavioral tagging process","resumen":"Several works have shown that the formation of different long-term memories relies on a behavioral tagging process. In other words, to establish a lasting memory, at least two parallel processes must occur: the setting of a learning tag (triggered during learning) that defines where a memory could be stored, and the synthesis of proteins, that once captured at tagged sites will effectively allow the consolidation process to occur. This work focused in studying which brain structures are responsible of controlling the synthesis of those proteins at the brain areas where memory is being stored. It combines electrical activation of the ventral tegmental area (VTA) and\/or the locus coeruleus (LC), with local pharmacological interventions and weak and strong behavioral trainings in the inhibitory avoidance and spatial object recognition tasks in rats. The results presented here strongly support the idea that the VTA is a brain structure responsible for regulating the consolidation of memories acting through the D1\/D5 dopaminergic receptors of the hippocampus to control the synthesis of new proteins required for this process. Moreover, they provide evidence that the LC may be a second structure with a similar role, acting independently and complementary to the VTA, through the &#946;-adrenergic receptors of the hippocampus.","palabras_clave":"Memory|Ventral Tegmental Area|Locus Coereleus| Behavioral Tagging"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7240,"idioma_id":4,"titulo":"Circumscription of the South American Moonwort Botrychium dusenii (Ophioglossaceae)","resumen":"The genus Botrychium (Ophioglossaceae) is comprised of about 30 widely distributed species. Because of their small size and few, yet variable, morphological characters, many questionable taxa have been described over the years. Since its description in 1906, B. dusenii has been treated as both a distinct species and as a variety of B. lunaria. It has also been variously divided into four taxa: B. lunaria var. dusenii, B. lunaria var. antarctica, B. ramosum var. patagonicum, and B. matricariifolium ssp. patagonica. The aims of this study are to evaluate validity of these taxa using characters of morphology, spore wall sculpture and size, and allelic composition using enzyme electrophoresis. We conclude that only one species of Botrychium occurs in the study area and recognize this as B. dusenii, a species distinct from B. lunaria. Enzyme electrophoresis and spore size suggest that B. dusenii is an allotetraploid derived through hybridization between a diploid member of B. lunaria complex and a diploid member of the B. campestre complex. We provide information about habitat, distribution, and full exsiccate citations.","palabras_clave":"Allozymes, |enzyme electrophoresis, |Botrychioid species, |fern spores"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7246,"idioma_id":5,"titulo":"Construcciones identitarias y sentidos de pertenencias en el espacio surandino al finalizar la guerra de independencia. Salta (Argentina) y Bolivia entre 1824-1826","resumen":"Nos proponemos analizar los procesos de construcción identitaria en el espacio surandino en el interregno 1824-1826, etapa de gestación de fronteras estatales. Se considerarán los casos de Salta y Bolivia en la conformación de la frontera para examinar las marcas identitarias emergentes en la construcción discursiva de las diferencias por parte de algunos actores de las elites locales.Palabras claves: construcciones identitarias, Salta, Bolivia, fronteras, década de 1820.","palabras_clave":"CONSTRUCCIONES IDENTITARIAS|SALTA Y BOLIVIA|FRONTERAS|DÉCADA DE 1820"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7250,"idioma_id":4,"titulo":"45S5 Bioglass® concentrations modulate the release of vancomycin hydrochloride from gelatin-starch films: evaluation of antibacterial and cytotoxic effects","resumen":"The aim of this work was to evaluate the release profile of vancomycin hydrochloride(VC), as well as the degradation, in vitro antistaphylococcal effect and cytotoxicity in MG-63 osteoblast-like cells of gelatin-starch (GS) films added with different concentrations of microparticles of the bioactive glass 45S5 (m-BG). The biomaterials were obtained through the gel casting method. Four different composites were prepared at four different weight percentages of m-BG: 0%, 5%, 10% and 15%. Glutaraldehyde 0.25 wt% (GA) was used as the cross-linker. The composites were characterized by scanning electron microscopy and the in vitro degradation of the films was studied by measuring the water uptake and weight loss. The drug release kinetics was quantified spectrophotometrically. The inhibition zone test and the plate countmethod were used to evaluate the antibacterial activity of the samples. Three staphylococcus strains were evaluated: Staphylococcus aureus ATCC6538, Staphylococcus aureus ATCC29213, and Staphylococcus epidermidis ATCC12228.Cytotoxicity effects were evaluated through the MTT assay. The addition of m-BG to GS films showed no effects on the amount of water uptake, but led to an increase in the weight loss over time, even with m-BG content. The release rate of VC was also affected by the increasing concentration of m-BG in the composite films. However, the antibacterial effects of the composites were not improved by this modulation. All composites strongly inhibited staphylococcal cells with similar strength. On the other hand, liquid extracts from the composites resulted in cytotoxic effects on MG-63 osteoblast-like cells due to the presence of GA, but not to the concentration of VC or m-BG.","palabras_clave":"BIOPOLYMERS|BIOACTIVE GLASS|VANCOMYCIN |STAPHYLOCOCCI"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7263,"idioma_id":5,"titulo":"Controversias acerca del TDAH y el metilfenidato en los debates sobre la medicalización en Argentina y Brasil","resumen":"El artículo sistematiza y analiza resultados de investigaciones conducidas en Argentina y Brasil sobre el uso del metilfenidato, la regulación de su prescripción yventa, y el desarrollo de discusiones por diferentes investigadores yprofesionales a cargo de la asistencia de personas diagnosticadas por TDAH enambos países. El artículo integra dos campos de investigación. En Argentina, se analizaron artículos periodísticos, datos numéricos oficiales y de organizaciones profesionales, y entrevistas semiestructuradas individuales y grupales a profesionales de la salud, realizadas entre 2007 y 2011. En Brasil se analizaron artículos periodísticos y de revistas especializadas, se realizaron observaciones participantes y entrevistas a educadores y profesionalesde salud. Las conclusiones sostienen que se han articulado organizaciones profesionales de ambos países, en un intento por promover el debate sobre la medicalización de la infancia y su despliegue en la sociedad.","palabras_clave":"TDAH|grupos de apoyo|marketing farmacéutico|medicalización|Argentina|Brasil"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7268,"idioma_id":5,"titulo":"Límites de las formas organizacionales hibridas: Evaluación teórica y análisis de investigaciones empíricas","resumen":"El concepto de formas organizacionales híbridas resulta clave para las investigaciones empíricas realizadas en el marco de la Nueva Economía Institucional. Las formas híbridas suelen considerarse un avance de dicho programa; sin embargo, aquí se argumenta lo contrario: evidencian limitaciones en sus hipótesis fundamentales.Este trabajo intenta mostrar cómo las formas híbridas emergen cuando la realidad social desborda los límites de las formas mercantiles de coordinación. Luego se ensayan nuevas hipótesis para superar esta limitación y se muestran las consecuencias de este problema sobre dos investigaciones empíricas que desbordaron los límites de las formas hibridas.","palabras_clave":"Formas organizacionales híbridas|Economía institucional|Mercados|Territorio"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7282,"idioma_id":4,"titulo":"Conditional tests for elliptical symmetry using robust estimators","resumen":"This paper presents a procedure for testing the hypothesis that the underlying distribution of the data is elliptical when using robust location and scatter estimators instead of the sample mean and covariance matrix. Under mild assumptions that include elliptical distributions without first moments, we derive the test statistic asymptotic behaviour under the null hypothesis and under special alternatives. Numerical experiments allow to compare the behaviour of the  tests based on the sample mean and covariance matrix with that based on robust estimators, under various elliptical distributions and dierent alternatives. We also provide a numerical comparison with other competing tests.","palabras_clave":"Bootstrap|Conditional test|Elliptical symmetry|Robust estimation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7285,"idioma_id":4,"titulo":"Improved gas selectivity of Polyetherimide membrane by the incorporation of PIM Polyimide phase","resumen":"The aim of this work was to prepare blend membranes of a polyetherimide (PEI) and different ratios of a microporous polyimide (PIM-B) in order to obtain an improved material for gas selectivity. Miscibility of the membranes was studied through FTIR, Fluorescence, UV-Vis, PLM images, XRD and DSC analysis. Gas permeability assays were also performed. Results showed blends were partially miscible along the different ratios due to the existence of: i) absorption shoulders at lower wavenumbers on the carbonyl stretching band; ii) red-shifting of Fluorescence and UV-Vis absorption bands; iii) decreasing of d-spacing as the amount of PIM-B phase increased and iv) composition-dependent glass transition temperatures (Tgs). The mobility selectivity (Di\/j) dominated H2 and O2 gas separations. High solubility coefficients (S) linked to PIM-B microporosity improved the ideal gas selectivity of the blend membranes. PEI\/PIM-B membrane at the ratio of 80\/20 showed impressive H2\/CO2 (8.66) and O2\/N2 (10.90) gas separation factors.","palabras_clave":"Instrinsic Microporosity|Polyimide|Gas Separation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7320,"idioma_id":4,"titulo":"Worsening of memory deficit induced by energy-     dense diet in a rat model of early-Alzheimer's disease is associated to neurotoxic A&#946;     species and independent of neuroinflammation","resumen":"Diet is a modifiable risk factor for Alzheimer´s disease (AD), but the mechanisms linking alterations in Peripherals metabolism and cognition remain unclear. Since it is especially difficult to study long-term effects of high-energy diet in individuals at risk for AD, we addressed this question by using the McGill-R-Thy1-APP transgenic rat model (Tg(+\/-)) that mimics presympomatic AD. Wild-type and Tg(+\/-) rats were exposed during 6 months to astandard diet or a Western diet (WD), high in saturated fat and sugar. Results from peripheral and hippocampal biochemical analysis and in situ respirometry showed that WD induced a metabolic syndrome and decreased presynaptic bioenergetic parameters without alterations in hippocampal insulin signaling or lipid composition.Cognitive tests, ELISA multiplex, Western blot, immunohistochemistry and RT-qPCR indicated that WD worsened cognition in Tg(+\/-) rats, increased hippocampal levels of monomeric A&#946; isoforms and oligomeric species, promoted deposits of N-Terminal pyroglutamate-A&#946; (A&#946;N3(pE)) in CA1 pyramidal neurons and interneurons, decreased transcript levels of genes involved in neuroprotective pathways such as Sirtuin-1 and increased nitrated proteins. Our results support the concept that in the presence of early A&#946; pathology, dietinducedmetabolic dysfunctions may contribute as a ?second hit? to impair cognition. Noteworthy, such effect is not mediated by higher microglia activation or disruption of blood brain barrier. However, it may be attributed to increased amyloidogenic processing of amyloid precursor protein, generation of A&#946;N3(pE)) and dysregulation of pathways governed by Sirtuin-1. This evidence reinforces the implementation of prophylactic interventions in individuals at risk for AD","palabras_clave":"ALZHEIMER`S DISEASE|WESTERN DIET|MEMORY DEFICIT|NEUROINFLAMMATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7351,"idioma_id":4,"titulo":"EVALUATION OF THE USE OF SLAG FROM THE MINING OF Au AND Ag AS A REPLACEMENT OF THE SAND IN CEMENT MORTARS","resumen":"To the benefit of gold minerals, extraction processes are generally applied by carrying out cyanidation and subsequent smelting to obtain dore thereby generating slags. The properties of the slag obtained vary depending on the origin of the mineral and on the type of load flux used. However, in the Pyrometallurgy literature the reuse of the slag generated at this stage of the process has not been analyzed.Therefore, the present research is focused on studying the characteristics of slags of minerals from San Juan province in Argentina, obtained at a laboratory scale, analyzing the possibility of recycling in case they present appropriate physical and chemical properties.Slag characterization (description) was made by using different techniques such as: chemical analysis with acid digestion and subsequent determination with ICP, structural study by applying optical microscopy techniques in white light mode and polarized light. Observation and semi-quantitative chemical analysis of the samples is completed by using an ESEM scanning electron microscope and analysis with the EDS technique. Finally, analyses about the physical properties obtained are carried out for subsequent use of the slag as cement","palabras_clave":"Slag|Mining|Gold|Silver"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7356,"idioma_id":4,"titulo":"Albendazole Microcrystal Formulations Based on Chitosan and Cellulose Derivatives: Physicochemical Characterization and In Vitro Parasiticidal Activity in Trichinella spiralis Adult Worms","resumen":"The oral route has notable advantages to administering dosage forms. One of the most important questions to solve is the poor solubility of most drugs which produces low bioavailability and delivery problems, a major challenge for the pharmaceutical industry. Albendazole is a benzimidazole carbamate extensively used in oral chemotherapy against intestinal parasites, due to its extended spectrum activity and low cost. Nevertheless, the main disadvantage is the poor bioavailability due to its very low solubility in water. The main objective of this study was to prepare microcrystal formulations by the bottom-up technology to increase albendazole dissolution rate, in order to enhance its antiparasitic activity. Thus, 20 novel microstructures based on chitosan, cellulose derivatives, and poloxamer as a surfactant were produced and characterized by their physicochemical properties and in vitro biological activity. To determine the significance of type and concentration of polymer, and presence or absence of surfactant in the crystals, the variables area under the curve, albendazole microcrystal solubility, and drug released (%) at 30 min were analyzed with a three-way ANOVA. This analysis indicated that the microcrystals made with hydroxyethylcellulose or chitosan appear to be the best options to optimize oral absorption of the active pharmaceutical ingredient. The in vitro evaluation of anthelmintic activity on adult forms of Trichinella spiralis identified system S10A as the most effective, of choice for testing therapeutic efficacy in vivo.","palabras_clave":"ALBENDAZOLE|BOTTOM-UP|MICROCRYSTAL CHITOSAN|IN VITRO ANTIPARASITIC ASSAY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7405,"idioma_id":4,"titulo":"First case of sterility associated with sex chromosomal  abnormalities in a jenny","resumen":"Chromosomal abnormalities are one of the main causes of genetic infertility in horses. Currently, their detection rate is rising due to the use of new diagnostic tools employing molecular markers linked to the sex chromosome pair. Despite genetic similarities, there are no previous reports of sterility associated with chromosomal abnormalities in the domestic donkey (Equus asinus). Hereby, we determined the presence of a chromosomal mosaicism in a female donkey with reproductive problems using molecular methodologies developed for horses. A two&#8208;and&#8208;a&#8208;half&#8208;year&#8208;old jenny characterized by morphological abnormalities of the reproductive tract was cytogenetically analysed using conventional and fluorescent techniques and a group of microsatellite markers (short tandem repeat, STR). At the same time, five ultrasound measures of the reproductive tract were taken and compared with eight contemporary jennies of the same breed. After slaughter, morphological examinations showed that the case study had a blind vaginal vestibule defining an empty pouch that covered the entrance of the cervical os. Histopathological studies demonstrated that this abnormal structure was compatible with a remnant hymen. Molecular markers, STR and fluorescent in situ hybridization determinations revealed that the animal was a 62, XX\/61,X mosaic and, therefore, the first case of chromosomal abnormalities in the sex pair reported in donkeys.","palabras_clave":"jenny|chromosomal abnormalities|mosaicism|molecular methods|ZOO-FISH|sterility|donkey"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7445,"idioma_id":4,"titulo":"Lactobacillus kefiri shows inter-strain variations in the amino acid sequence of the S-layer proteins","resumen":"The S-layer is a proteinaceous envelope constituted by subunits that self-assemble to form a twodimensional lattice that covers the surface of different species of Bacteria and Archaea, and it could be involved in cell recognition of microbes among other several distinct functions. In this work, both proteomic and genomic approaches were used to get knowledge about the sequences of the S-layer proteins (SLPs) encoding genes expressed by six aggregative and sixteen non-aggregative strains of potentially probiotic Lactobacillus kefiri. Peptide mass fingerprint (PMF) analysis confirmed the identity of SLPs extracted from L. kefiri, and based on the homology with phylogenetically related species, primers located outside and inside the SLP-genes were employed to amplify genomic DNA. The O-glycosylation site SASSAS was found in all L. kefiri SLPs. Ten strains were selected for sequencing of the complete genes. The total length of the mature proteins varies from 492 to 576 amino acids, and all SLPs have a calculated pI between 9.37 and 9.60. N-terminal region is relatively conserved and shows a high percentage of positively charged amino acids. Major differences among strains are found in the C-terminal region. Different groups could be distinguished regarding the mature SLPs and the similarities observed in the PMF spectra. Interestingly, SLPs of the aggregative strains are 100% homologous, although these strains were isolated from different kefir grains. This knowledge provides relevant data for better understanding of the mechanisms involved in SLPs functionality and could contribute to the development of products of biotechnological interest from potentially probiotic bacteria.","palabras_clave":"LACTOBACILLUS KEFIRI|SURFACE PROPERTIES|GLYCOPROTEIN|S-LAYER PROTEINS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7450,"idioma_id":5,"titulo":"Caracterizacion de ovinos criollos argentinos utilizando indices zoometricos","resumen":"La utilización racional de los recursos genéticos animales implica estudiar sus características zootécnicas y productivas mediante datos objetivos. Para cumplir con esta premisa en el caso de la raza ovina criolla argentina, aún falta mucho por hacer. Es la primera raza ovina del país, está distribuida en casi todas las provincias y ocupa el lugar tercero de las existencias ovinas actuales. El objetivo del trabajo fue estudiar la morfología de las ovejas criollas de cuatro provincias argentinas utilizando índices zoométricos, de tal manera de reconocer sus características etnológicas y sus aptitudes funcionales. Para ello se trabajo con 203 ovejas adultas de acuerdo a su cronometría dentaria: 59 pertenecientes a la provincia de  Buenos Aires (BA); 40 a Corrientes (CO); 60 a Santiago del Estero (SE) y 44 a Salta (SA). Se calcularon ocho índices zoométricos, cuatro de tipo Etnológico: Índice Cefálico (ICE); Índice Torácico (ITO); Índice Corporal (ICO); Índice Pelviano (IPE) y cuatro de tipo Funcional: Índice de Profundidad Relativa (IPR); Índice Pelviano Transversal (IPT); Índice Pelviano Longitudinal (IPL); Índice de Cortedad Relativa (ICR). Se efectuaron análisis estadísticos descriptivos, ANOVA y test de Tuckey para detectar diferencias entre regiones, correlaciones lineales entre los índices y Análisis de Componentes Principales para los índices etnológicos y para los funcionales separadamente. Los resultados respecto de los índices etnológicos revelan que las cuatro regiones comparten características raciales en común, aunque presentan variabilidad intrapoblacional, siendo las más homogéneas las ovejas salteñas y las de mayor variabilidad las bonaerenses, probablemente obedeciendo a la adaptación de los animales a los ambientes de cada región. Los índices funcionales indican que en las cuatro regiones las ovejas son aptas para ser utilizadas con doble propósito: carne-lana, resultando también las ovejas salteñas las más uniformes y con mejor conformación carnicera.","palabras_clave":"PRODUCCION OVINA |DIVERSIDAD|MORFOLOGIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7491,"idioma_id":4,"titulo":"Pectinolytic yeasts from cold environments: novel findings of Guehomyces pullulans, Cystofilobasidium infirmominiatum and Cryptococcus adeliensis producing pectinases","resumen":"One hundred and three yeastsisolated from soil samples from King George Island and Tierra del Fuego provincewere screened in relation with their capability to produce pectinolyticenzymes. Although all the yeasts showed well-developed colonies at 20 °C, onlyeight showed a clear halo around the colony, indicative of pectin degradation.A secondary screening demonstrated that only four yeasts were capable toproduce pectinases at low temperatures (8 °C). It could be seen that theselected yeasts were able to grow and produce high levels of polygalacturonase activitywhen submerged fermentations were performed using pectin-containing fruitwastes as substrates. None of the strains produced neither lyase norrhamnogalacturonan hydrolase activities. Regarding pectin esterase activity, itwas only produced in lower amounts by G. pullulans 8E (0.022 U ml&#8722;1). A TLC analysis of the substrate cleavage patternof the pectinolytic systems was consistent with an endo-type activity. Theclarification of apple juice was only accomplished by G. pullulans pectinolyticsystem, with a clarification of 80% (%T650) using 4 U\/ml of enzyme at 20 °C. Asfar as we concern this work describes for the first time the production ofpectinases by the cold adapted yeasts species Cystofilobasidium infirmominiatum,Cryptococcus adeliensis and G. pullulans","palabras_clave":"COLD ACTIVE ENZYMES|POLIGALACTURONASES|FRUIT JUICE CLARIFICATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7556,"idioma_id":4,"titulo":"Chronic toxicity of arsenic during Rhinella arenarum embryonic and larval development: Potential biomarkers of oxidative stress and antioxidant response","resumen":"The Argentinean autochthonous toad Rhinella arenarum was selected to study the chronic toxicity of arsenic (As) and the biochemical responses elicited by exposure to As in water during embryonic and larval development. Significant decreases in the total reactive antioxidant potential and in catalase activity were observed in individuals exposed chronically to sublethal concentrations of As, which is indicative of an oxidative stress situation. However, an antioxidant response was elicited during chronic exposure to As, as evidenced by the increase in endogenous reduced glutathione content and glutathione-related enzymatic activities such as glutathione S-transferase (GST) and glutathione reductase. This protective response might prevent a deeper decline in the antioxidant system and further oxidative damage. Alternatively, it might be linked to As conjugation with reduced glutathione for its excretion. Considering the sustained increase in GST activity and the decrease in the total antioxidant reactive potential observed, the authors propose them as good candidates to be used as biomarkers during As exposure. Interestingly, glutathione reductase activity was inhibited at a very low concentration of As considered safe for aquatic life. Environ Toxicol Chem 2017;36:1614?1621. © 2016 SETAC.","palabras_clave":"Amphibians|Stress response|Aquatic toxicology|Glutathione S-transferase|Total reactive antioxidant potential|Detoxification"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7569,"idioma_id":4,"titulo":"Determination of polybrominated diphenyl ethers in milk samples. Development of green extraction coupled techniques for sample preparation","resumen":"Ultrasound-assisted extraction (UAE), cloud point extraction (CPE), and ultrasound back-extraction (UABE) techniques have been coupled for lixiviation, preconcentration, and cleanup of polybrominated diphenyl ethers (PBDEs) from milk samples for determination by gas chromatography-electron capture detection (GC-ECD). Physicochemical parameters that affect the efficiency of the extraction system were investigated using a design of experiments based on multivariate statistical tools, and considering the sample matrix along the development. The coupling of the leaching step, UAE, enhanced ca. 3.5 times the extraction efficiency of the former sample preparation methodology (CPE-UABE) leading to cleaner sample extracts suitable for GC analysis. Under optimum conditions, the proposed methodology exhibits successful performance in terms of linearity and precision, with recoveries in the range of 68&ndash;70% and LODs within the range 0.05&ndash;0.5 ng\/g dry weight (d.w.). The proposed sample preparation methodology coupled three green analytical techniques. It expands the application frontiers of CPE for the analysis of biological samples by GC. The optimized methodology was used for determination of PBDEs in powder milk samples, from both commercial and human sources.","palabras_clave":"MILK|PBDE|GREEN CHEMISTRY|SURFACTANTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7588,"idioma_id":4,"titulo":"Simultaneous analysis of DAZ family members and CDC25A: A predicting study for successful TESE","resumen":"The analysis of single DAZ genes has shown that their dysfunction leads to abnormal spermatogenesis and may cause infertility. They were, however, poorly associated to sperm recovery during assisted reproductive treatments. Whether the simultaneous expression of  DAZ genes and its substrates may provide better information of testicular damage and success of sperm recovery in infertile patients has not been yet analyzed. We evaluated eight 8 men (29-38 years-old) presenting idiopathic infertility and non-obstructive azoospermia without infection processes diagnosed by open testicular biopsy. None of these patients presented showed genitourinary infections, varicocele, hypogonadotropic hypogonadism, chromosome anomalies abnormalities and obstruction or agenesis of the seminal ducts.We did not observe find an association between the expression levels of DAZ genes family members analyzed by real time PCR with the diagnosis of the testicular pathology. However, a positive correlation between the mRNA transcript ratios of DAZ gene family members and CDC25A were was detected, irrespective of the testicular pathology. Moreover, we found that,  irrespective of the testicular pathology, the group of patients with failure in sperm retrieval showed a significantly lower expression levels of DAZ, BOULE and CDC25A compared to the group of patients with successful sperm retrieval.These results suggest that DAZ genes would be collectively rather than individually altered in patients with HS and MA","palabras_clave":"DAZ genes|CDC25A|HYPOSPERMATOGENESIS|MATURATION ARREST"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7597,"idioma_id":4,"titulo":"Pulsed laser deposition of PbTe under monopulse and multipulse regime","resumen":"The aim of this paper is to compare PLD technique with monopulse and multipulse nanosecond laser excitation. We show the feasibility of depositing nanometric layers of PbTe employing the regimes already mentioned. Each of the grown layers were characterized by XRD, EDXS, SEM, Spectroscopic Elipsometry, AFM and the thickness was measured by echanic profilometry. We have conducted comparative experiments to show the advantagesand drawbacks of making PLD with mono and multipulse nanosecond laser.","palabras_clave":"Pulsed Laser Deposition|Multipulse Ablation|PbTe|Laser Ablation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7609,"idioma_id":4,"titulo":"Antifungal metabolites from Schinopsis balansae Engl (Anacardiaceae): isolation, identification and evidences of their mode of action on Fusarium graminearum Schwabe","resumen":"An antifungal activity-directed fractionation of leaf constituents from Schinopsis balansae on Fusarium graminearum yielded a fraction mainly made of a mixture of  Four 3-n-heptadec(en)ylcatechols (PALK). The PALK fraction showed on macroconidia germination a MIC100 value of 500 &#956;g\/mL which was twofold higher than that required for prothioconazole (MIC100 = 250 &#956;g\/mL). Sublethal concentrations of PALK modify the morphogenesis in germinating macroconidia, and decreased fungal production of H2O2 and deoxynivalenol biosynthesis at early fungal growth. Mixes of PALK and prothioconazole showed a synergic interaction. Our &ndings suggest that PALK constituents might restrict the adherence of F. graminearum to the surface of its hosts and its virulence on susceptible cereals. They deserve further research as additives of azole fungicides against F. graminearum.","palabras_clave":"Deoxynivalenol|oxidative stress|Schinopsis|urushiol"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7611,"idioma_id":4,"titulo":"Deflections in sawn timber beams with stochastic properties","resumen":"A stochastic model is proposed to study thebehavior of structural sawn beams of Argentinean Eucalyptusgrandis with the aim of improving the predictabilityof the elastic deformations. The enhancement of the midspandeflection calculation is based on a probabilisticmodel of the Modulus of Elasticity (MOE) and the representationof its lengthwise variability through a randomfield. The standard model that uses a MOE variableassumed random from piece to piece but deterministic(constant) within each piece is obtained as a particularcase. In order to obtain a statistical representation of theMOE, the Principle of Maximum Entropy (PME) isemployed. Experimental data obtained from bending testsare employed to find the parameters of the derived ProbabilityDensity Function (PDF). The PDF of the mid-spandeformations is numerically obtained through theStochastic Finite Element Method (SFEM) and MonteCarlo Simulations (MCS). Numerical results are validatedwith experimental values. Deflections of structural sizedbeams under usual loads are obtained. Finally, thestochastic model is used to compare with the serviceabilityrequirements established in the Argentinean design code. Itis shown that the structural performance of timber beams isfound through a more realistic material approach.","palabras_clave":"TIMBER |BEAM|MOE LENGTHWISE VARIABILITY|RELIABILITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7615,"idioma_id":5,"titulo":"Virtudes de la doctrina  y errores de la política. Monseñor Gustavo Franceschi ante los ?totalitarismos? soviético, fascista y nacionalsocialista.","resumen":"En el uso del concepto totalitarismo se compendian una buena parte de los debates ideológicos  y los posicionamientos políticos del siglo XX.  Ese uso, y muchas veces abuso, quedó, por lo tanto, enredado en un empleo instrumental, en un juego comparativo mezquino entre sus diferentes expresiones y en una lectura que olvidaba o resaltaba matices de acuerdo al lugar que ocupara y los intereses que defendiera quien lo usaba. Como señala Enzo Traverso, pocos términos de la cultura política moderna son tan ambiguos, maleables y polimorfos como el vocablo Totalitarismo (2005, 99-110).Totalitarismo es una palabra que forma parte del léxico de todas las corrientes políticas e ideológicas, pero en este artículo nos aproximaremos al uso que le dio un sector de las derechas argentinas contemporáneas, más específicamente la derecha católica de inclinación corporativista y, dentro de ella, se atenderá a la perspectiva que construyó  (en artículos escritos desde 1919, recopilados como libros en los primeros años cuarenta) Monseñor Gustavo Franceschi, reconocido intelectual del catolicismo social argentino.","palabras_clave":"totalitarismo|fascismo|nacional socialismo|catolicismo social"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7662,"idioma_id":4,"titulo":"Why predation is not a controlling factor of phytoplankton in a Neotropical shallow lake: a morpho-functional perspective","resumen":"This work explores the reasons why predation plays a minor role in structuring phytoplankton composition in a Neotropical shallow lake. Phytoplankton, zooplankton, and fish were sampled from a shallow lake over the course of a year, and the stomach contents of 80 individuals of the dominant omnivorous?planktivorous fish species were analyzed. The field study was complemented with a 5-day microcosm experiment in which the predation effects of micro, meso, and macrozooplankton were measured. Stomach content analysis revealed that fishpredation was high, and primarily comprised by Cladocera (Ivlev?s index [0.75). Both meso and macrozooplankton fractions are able to feed on colonial cyanobacteria, silica cell-wall organisms ( lm), and mixotrophic flagellate ([35 lm). Macrozooplankton, however, can feed on single cells, mucilaginous colonies, non-mucilaginous colonies, and silica cell-wall organisms ([35 lm) (P&#65533;.05 in all cases). Our results support the idea that absence of predation on phytoplankton is mainly mediated by fish predation on zooplankton and morpho-functional characteristics of algae which prevent zooplankton predation; showing fish a lack of direct predation effect on phytoplankton.","palabras_clave":"Top down control|Phytoplankton features|Omnivorous fish effects|Zooplankton size"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7674,"idioma_id":4,"titulo":"Estimates of the actual relationship between half-sibs in a pig population","resumen":"Genomic relationships based on markers capture the actual instead of the expected (based on pedigree) proportion of genome shared identical by descent (IBD). Several methods exist to estimate genomic relationships. In this research, we compare four such methods that were tested looking at the empirical distribution of the estimated relationships across 6704 pairs of half-sibs from a cross-bred pig population. The first method based on multiple marker linkage analysis displayed a mean and standard deviation (SD) in close agreement with the expected ones and was robust to changes in the minor allele frequencies (MAF). A single marker method that accounts for linkage disequilibrium (LD) and inbreeding came second, showing more sensitivity to changes in the MAF. Another single marker method that considers neither inbreeding nor LD showed the smallest empirical SD and was the most sensible to changes in MAF. A higher mean and SD were displayed by VanRaden´s method, which was not sensitive to changes in MAF. Therefore, the method based on multiple marker linkage analysis and the single marker method that considers LD and inbreeding performed closer to theoretical values and were consistent with the estimates reported in literature for human half-sibs.","palabras_clave":"Actual relationships|Estimation methods|Genomic selection|Identity by descent"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7683,"idioma_id":4,"titulo":"On the computation of rational points of a hypersurface over a finite field","resumen":"We design and analyze an algorithm for computing rational points of hypersurfaces defined over a finite field based on searches on 'vertical strips', namely searches on parallel lines in a given direction. Our results show that, on average, less than two searches suffice to obtain a rational point. We also analyze the probability distribution of outputs, using the notion of Shannon entropy, and prove that the algorithm is somewhat close to any 'ideal' equidistributed algorithm.","palabras_clave":"Hypersurfaces over finite fields|Rational points|Algorithms|Average-case complexity|Value sets|Shannon entropy"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7701,"idioma_id":4,"titulo":"Compatibilization Strategies for Recycling Applications of High Impact Polystyrene \/ Acrylonitrile Butadiene blends","resumen":"Plastic waste from electrical and electronic equipment (WEEE) is growing up exponentially fast during the last two decades, mainly due to short lifetime of technological products like cellphones or computers. This situation entailed an increase in the accumulation of specific plastic materials such Acrylonitrile?Butadiene?Styrene (ABS), High Impact Polystyrene (HIPS), Polycarbonate, among others. These plastics can be recycled by themselves but their separation by type is neither easy nor economically viable, then recycling them together as a blend is the most economically viable alternative. However, mechanical properties suffer a deterioration and to enhance phase adhesion and add value to this WEEE blend, an adequate compatibilization is needed. To choose a compatibilization route an accurate comprehension of blends behavior has to be done. In this work, a systematical study of the addition compatibilization of HIPS\/ABS blends was performed. Besides results were focus to WEEE recycling, in order to comprehend this complex system, virgin base materials were used. Relative amount effect on self-compatibilization was analyzed by two different HIPS\/ABS blends, one with major content of HIPS and other with major content of ABS. Also, two different copolymers were used as compatibilizer, Styrene?Acrylonitrile (SAN) and Styrene?Butadiene?Styrene and the concentrations chosen were 2 and 20 wt%. The best performance was achieved for blend with major content of ABS by using 2 % of SAN, obtaining a compatibilized blend with a general improvement of mechanical properties specially toughness in a 350 % and elongation in a 77 % respect to the physical blend.","palabras_clave":"ABS|HIPS|compatibilization strategies|WEEE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7727,"idioma_id":4,"titulo":"Peanut seed cultivars with contrasting resistance to Aspergillus parasiticus colonization display differential temporal response of protease inhibitors","resumen":"Significant efforts are being made to minimize aflatoxin contamination in peanut seeds and one possible strategy is to understand and exploit the mechanisms of plant defense against fungal infection. In this study we have identified and characterized, at biochemical and molecular levels, plant protease inhibitors (PPIs) produced in peanut seeds of the resistant PI337394 and the susceptible Forman cultivar during A.parasiticus colonization. With chromatographic methods and 2D electrophoresis-massspectrometry we have isolated and identified four variants of Bowman-Birk trypsin inhibitor (BBTI) and a novel Kunitz-type protease inhibitor (KPI) produced in response to A. parasiticus colonization. KPI was detected only in the resistant cultivar while BBTI was produced in the resistant cultivar in a higher concentration than susceptible cultivar and with different isoforms. The kinetic expression of KPI and BBTI genes along with trypsin inhibitory activity was analyzed in both cultivars during infection. In the susceptible cultivar an early PPI activity response was associated with BBTIoccurrence. Meanwhile in the resistant cultivar a later response with a larger increase in PPI activity was associated with BBTI and KPI occurrence. The biological significance of PPI in seed defense against fungal infection was analyzed and linked to inhibitory properties on enzymes released by the fungus during infection, and to the antifungal effect of KPI.","palabras_clave":"peanut|aflatoxin|protease inhibitors|defense mechanism"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7743,"idioma_id":5,"titulo":"RELIGION, MEDIO AMBIENTE Y DESARROLLO SUSTENTABLE: LA INTEGRALIDAD EN LA COSMOLOGIA CATOLICA","resumen":"El artículo realiza una investigación sobre los aportes, presencias y criticas al accionar de diversas empresas estatales y privadas , nacionales e internacionales en lo relacionado con el medio ambiente por parte de grupos católicos organizados en el conjunto del territorio argentino en los últimos 10 años. La enciclica del actual papa Francisco 'Laudato si' sobre las causas y consecuencias de la contaminanción del medio ambien  como los juegos de poder e intereses económicos en pugna apuntalan esas acciones. Al mismo tiempo el articulo investiga como ese accionar es tambien prolongación de la critica al liberalimso y al capitalismo desregulado por parte de lo que hemos denominado como catolicismo integral.","palabras_clave":"RELIGION|MEDIO AMBIENTE|DESARROLLO|ARGENTINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7749,"idioma_id":4,"titulo":"Sharing beliefs among agents with different degrees of credibility","resumen":"This paper introduces an approach for sharing beliefs in collaborative multi-agent application domains where some agents can be more credible than others. In this context, we propose a formalization where every agent has its own partial order among its peers representing the credibility the agent assigns to its informants; each agent will also have a belief base where each sentence is attached with an agent identifier which represents the credibility of that sentence. We define four different forwarding criteria for computing the credibility information for a belief to be forwarded, and for determining how the receiver should handle the incoming information; the proposal considers both the sender?s and the receiver?s points of view with respect to the credibility of the source of the information.","palabras_clave":"FORWARDING| TRUST|CREDIBILITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7750,"idioma_id":4,"titulo":"NOVEL USE OF ALL-TRANS-RETINOIC ACID IN A MODEL OF LIPOPOLYSACCHARIDE-IMMUNOSUPPRESSION TO DECREASE THE GENERATION OF MYELOID-DERIVED SUPPRESSOR CELLS BY REDUCING THE PROLIFERATION OF CD34+ PRECURSOR CELLS","resumen":"All-trans-retinoic acid (ATRA) is a derivative of vitamin A with antiproliferative properties. Endotoxin shock and subsequent immunosuppression (IS) by lipopolysaccharide (LPS) stimulates myelopoiesis with expansion of myeloidderived suppressor cells (MDSC). Since we have previously shown that ATRA reverses the IS state by decreasing functional MDSC, our aim was to investigate if ATRA was able to modulate MDSC generation by regulating myelopoiesis in murine hematopoietic organs. We found that ATRA administration in vivo and in vitro decreased the number of CD34þ precursor cells that were increased in IS mice. When we studied the cellular mechanisms involved, we did not find any differences in apoptosis of CD34+ precursors or in the differentiation of these cells to their mature counterparts. Surprisingly, ATRA decreased precursor proliferation, in vitro and in vivo, as assessed by a reduction in the size and number of colony forming units generated from CD34þ cells and by a decreased incorporation of 3H-thymidine. Moreover, ATRA administration to IS mice decreased the number of MDSC in the spleen, with a restoration of T lymphocyte proliferation and a restitution of the histological architecture. Our results indicate, for the first time, a new use of ATRA to abolish LPS-induced myelopoiesis, affecting the proliferation of precursor cells, and in consequence, decreasing MDSC generation, having a direct impact on the improvement of immune competence. Administration of ATRA could overcome the immunosuppressive state generated by sepsis that often leads to opportunistic life-threatening infections. Therefore, ATRA could be considered a complementary treatment to enhance immune responses.","palabras_clave":"Retinoic Acid|Lipopolysaccharide|sepsis|myeloid derived supressor cells"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7767,"idioma_id":5,"titulo":"Cadenas Globales de Valor y Desarrollo Económico","resumen":"El presente artículo procura analizar algunos aportes teóricos y empíricos del corpus de las ?cadenas globales de valor? (CGV) al estudio del desarrollo económico. Primero, se revisan los elementos conceptuales centrales del paradigma de las CGV, para luego analizar las tendencias centrales de la geografía económica mundial en la era de las CGV (enfatizando en lo ocurrido a partir de los años ?90). Por último se cierra con algunas reflexiones en torno a la inserción en CGV y las posibilidades de desarrollo. Como conclusión principal, destacamos que la alternativa no es ?mucha o poca inserción en las CGV? y, que en todo caso, el desafío sigue siendo evitar aquellas formas de inserción internacional que impulsen un crecimiento empobrecedor y excluyente.","palabras_clave":"CADENA GLOBAL DE VALOR|DESARROLLO ECONOMICO|ARGENTINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7816,"idioma_id":4,"titulo":"The susceptibility of Varroa destructor against oxalic acid: a study case","resumen":"Varroa destructor Anderson et Trueman is an ectoparasitic mite of the honey bee Apis mellifera L. and it must be controlled in managed bee colonies to maintain colony health. Taking into account that these mites are now resistant to synthetic acaricides worldwide, oxalic acid was suggested as an alternative for Varroa control. Oxalic acid is one of the most common natural miti-cides used against varroosis by spraying and sublimation administration techniques. It is a natural constituent of honey, very ac-tive against the Varroa mite, safe to use for beekeepers, and has no residue problems. Nevertheless, some authors have predicted that the risk of developing resistance to oxalic acid in mites is high. The objective of this research was to assess the susceptibility to oxalic acid of a V. destructor population belonging to a commercial apiary where 64 consecutive control treatments with this acid were performed. Bioassays to assess the oxalic acid susceptibility were performed on two mite populations: (1) a ?focal&#8223; population consisting of mites previously exposed to oxalic acid treatments, and (2) a ?naïve&#8223; population that was never exposed to this acid, which allows setting a reference in the absence of historical data on our ?focal&#8223; mites. The results reported here sug-gest that the Varroa population exposed during 8 successive years to oxalic acid treatments remains susceptible to this acid.&nbsp;","palabras_clave":"Varroa destructor|susceptibility|oxalic acid|honey bee"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7826,"idioma_id":4,"titulo":"Osteological postcranial traits in hylid anurans indicate a morphological continuum between swimming and jumping locomotor modes","resumen":"Anurans exhibit a particularly wide range of locomotor modes that result in wide variations in their skeletal structure. This paper investigates the possible correlation between morphological aspects of the hylid postcranial skeleton and their different locomotor modes and habitat use. To do so, we analyzed 18 morphometric postcranial variables in 19 different anuran species representative of a variety of locomotor modes (jumper, hopper, walker, and swimmer) and habitat uses (arboreal, bush, terrestrial, and aquatic). Our results show that the evolution of the postcranial hylid skeleton cannot be explained by one single model, as for example, the girdles suggest modular evolution while the vertebral column suggests other evolutionary modules. In conjunction with data from several other studies, we were able to show a relationship between hylid morphology and habitat use; offering further evidence that the jumper\/swimmer and walker\/hopper locomotor modes exhibit quite similar morphological architecture. This allowed us to infer that new locomotor modalities are, in fact, generated along a morphological continuum.","palabras_clave":"POSTCRANIAL SKELETON|LOCOMOTOR MODES|HABITAT USE|HYLIDS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7851,"idioma_id":4,"titulo":"Monadic BL-algebras: The equivalent algebraic semantics of Hájek's monadic fuzzy logic","resumen":"In this article we introduce the variety of monadic BL-algebras as BL-algebras endowed with two monadic operators $orall$ and $exists$. After a study of the basic properties of this variety we show that this class is the equivalent algebraic semantics of the monadic fragment of Hájek´s basic predicate logic. In addition, we start a systematic study of the main subvarieties of monadic BL-algebras, some of which constitute the algebraic semantics of well-known monadic logics: monadic Gödel logic and monadic L ukasiewicz logic. In the last section we give a complete characterization of totally ordered monadic BL-algebras.","palabras_clave":"MATHEMATICAL FUZZY LOGIC|MONADIC LOGIC|BL-ALGEBRAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7863,"idioma_id":4,"titulo":"Trophoblast cells inhibit neutrophil extracellular trap formation and enhance apoptosis through vasoactive intestinal peptide-mediated pathways","resumen":"STUDY QUESTION: Do human trophoblast cells modulate neutrophil extracellular trap (NET) formation, reactive oxygen species (ROS)synthesis and neutrophil apoptosis through mechanisms involving vasoactive intestinal peptide (VIP)?SUMMARY ANSWER: Trophoblast cells inhibited NET formation and ROS synthesis and enhanced neutrophil apoptosis through VIPmediatedpathways in a model of maternal?placental interaction.WHAT IS KNOWN ALREADY: Immune homeostasis maintenance at the maternal?placental interface is mostly coordinated by trophoblastcells. Neutrophil activation and NET formation increases in pregnancies complicated by exacerbated pro-inflammatory responses. VIPhas anti-inflammatory and immunosuppressant effects and is synthesized by trophoblast cells.STUDY DESIGN, SIZE, DURATION: This is a laboratory-based observational study that sampled circulating neutrophils from 50 healthyvolunteers to explore their response in vitro to factors derived from human trophoblast cells.PARTICIPANTS\/MATERIALS, SETTING, METHODS: Peripheral blood neutrophils were isolated from healthy volunteers andtested in vitro with first trimester trophoblast cell line (Swan-71 and HTR8) conditioned media (CM) or with VIP. The effect of VIP andtrophoblast CM on NET formation was assessed by co-localization of elastase and DNA by confocal microscopy, DNA release and elastaseactivity measurement. Neutrophil apoptosis was determined by flow cytometry or fluorescence microscopy. ROS formation was assessed byflow cytometry with a fluorescent probe. VIP silencing was performed by siRNA transfection. For phagocytosis of apoptotic neutrophils,autologous monocytes were sampled, and engulfment and cytokines were assessed by flow cytometry and ELISA.MAIN RESULTS AND THE ROLE OF CHANCE: Trophoblast CM and 10 nM VIP promoted neutrophil deactivation by preventingphorbol myristate acetate?induced NET formation and ROS synthesis while they increased neutrophil spontaneous apoptosis and reversedthe anti-apoptotic effect of lipopolysaccharide (all P < 0.05 versus control). The effects of trophoblast CM were prevented by a VIP antagonistor when VIP knocked-down trophoblast cells were used (P < 0.05 versus control). Neutrophils driven to apoptosis by trophoblast CM couldbe rapidly engulfed by monocytes without increasing IL-12 production.LARGE SCALE DATA: Not applicable.LIMITATIONS, REASONS FOR CAUTION: The mechanisms of neutrophil deactivation by trophoblast VIP are based on the resultsobtained with neutrophils drawn from peripheral blood of healthy individuals interacting with trophoblast cell lines in vitro. These studies weredesigned to investigate biological processes at the cellular and molecular level; therefore, they have the limitations of studies in vitro and it isnot possible to ascertain if these mechanisms operate similarly in vivo. We tested 50 neutrophil samples from healthy volunteers that have anormal variability in their responses. Cell lines derived from human trophoblast were used, and we cannot rule out a differential behavior oftrophoblast cells in contact with neutrophils in vivo.WIDER IMPLICATIONS OF THE FINDINGS: Results presented here are consistent with an active mechanism through which neutrophilsin contact with trophoblast cells would be deactivated and silently cleared by decidual macrophages throughout pregnancy. They supporta novel immunomodulatory role of trophoblast VIP on neutrophils at the placenta, providing new clues for pharmacological targeting ofimmune and trophoblast cells in pregnancy complications associated with exacerbated inflammation.","palabras_clave":"trophoblast cells|neutrophils|neutrophil apoptosis|phagocytosis of apoptotic cells|vasoactive intestinal peptide|neutrophil extracellular traps"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7887,"idioma_id":5,"titulo":"Revisitando dos estudio clave sobre niños y jóvenes sin domicilio: a propósito de los trabajos de Tobías Hetch y MaryseMarpsat","resumen":"Este artículo recupera los aportes de dos trabajos considerados clave en el campo de estudios de niños y jóvenes sin hogar: uno llevado a cabo en Francia por M. Marpsat, J. M. Firdion y equipo 'The INED research on homeless', otro, desarrollado en Brasil por T. Hetch 'At home in the street',  haciéndolos dialogar con una experiencia de investigación conducida en el contexto de la ciudad de La Plata -capital de la provincia de Buenos Aires- sobre niños y jóvenes que trabajan y\/o viven en la calle.  Se busca hacer una contribución  teórica y metodológica a este campo de estudios, a partir del ordenamiento de ciertos ejes de lectura que permitan dilucidar aspectos sustantivos a considerar en investigaciones sobre este colectivo.","palabras_clave":"NIÑOS|JÓVENES|SITUACIÓN DE CALLE|CONTRIBUCIONES TEÓRICO-METODOLÓGICAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7908,"idioma_id":5,"titulo":"2.\t?Historia Reciente: apuntes sobre un campo de investigación en expansión?","resumen":"Este artículo presenta las que consideramos características centrales del campo de la Historia Reciente, que en la Argentina desarrolla en la última década un proceso de consolidación intelectual e institucional. Ese proceso de expansión se enmarca en la cantidad de investigaciones plasmadas en tesis,artículos, libros y ponencias. Repasamos para ello los principales problemas epistemológicos y políticos de esta área de la historiografía, presentamos algunos datos cuantitativos para dar cuenta del proceso de expansión,proponemos un balance de los principales nudos en que se concentra la producción y señalamos las áreas de vacancia y desafíos con que se encuentra el campo de la Historia Reciente en la actualidad.","palabras_clave":"Historia Reciente|Historiografia"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7923,"idioma_id":4,"titulo":"Phenotypic plasticity en Drosophila cactophilic species: the effect of competition, density and breeding sites.","resumen":"Changes in the environmental conditions experienced by naturally occurring populations are frequently accompanied by changes in adaptive traits allowing the organism to cope with environmental unpredictability. Phenotypic plasticity is a major aspect of adaptation and it has been involved in population dynamics of interacting species. In this study, phenotypic plasticity (i.e., environmental sensitivity) of morphological adaptive traits were analyzed in the cactophilic species Drosophila buzzatii and Drosophila koepferae (Diptera: Drosophilidae) considering the effect of crowding conditions (low and high density), type of competition (intraspecific and interspecific competition) and cacti hosts (Opuntia and Columnar cacti). All traits (wing length, wing width, thorax length, wing loading and wing aspect) showed significant variation for each environmental factor considered in both Drosophila species. The phenotypic plasticity pattern observed for each trait was different within and between these cactophilic Drosophila species depending on the environmental factor analyzed suggesting that body size-related traits respond almost independently to environmental heterogeneity. The effects of ecological factors analyzed in this study are discussed in order to elucidate the causal factors investigated (type of competition, crowding conditions and alternative host) affecting the election of the breeding site and\/or the range of distribution of these cactophilic species.","palabras_clave":"ADAPTATION|BODY SIZE|COLONIZATION|DROSOPHILA CACTOPHILIC SPECIES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7926,"idioma_id":4,"titulo":"Fluorinated oxysterol analogues: Synthesis, molecular modelling and LXR&#946; activity.","resumen":"Liver X receptors (LXRs) are nuclear receptors that play central roles in the transcriptional control of lipid metabolism. The ability of LXRs to integrate metabolic and inflammation signaling makes them attractive targets for intervention in human metabolic diseases. Several oxidized metabolites of cholesterol (oxysterols) are endogenous LXR ligands, that modulate their transcriptional responses. While 25R-cholestenoic acid is an agonist of the LXRs, the synthetic analogue 27-norcholestenoic acid that lacks the 25-methyl is an inverse agonist. This change in the activity profile is triggered by a disruption of a key interaction between residues His435 and Trp457 that destabilizes the H11-H12 region of the receptor and favors the binding of corepressors. The introduction of fluorine atoms on the oxysterol side chain can favor both hydrophobic interactions as well as hydrogen bonds with the fluorine atoms and may thus induce changes in the receptor that may lead to changes in the activity profile. To evaluate these effects we have synthesized two fluorinated 27-nor-steroids, analogues of 27-norcholestenoic acid, the 25,25-difluoroacid and the corresponding 26-alcohol. The key step was a Reformatsky reaction on the C-24 cholenaldehyde, with ethyl bromodifluoroacetate under high intensity ultrasound (HIU) irradiation, followed by a Barton-McCombie type deoxygenation. Activity was evaluated in a luciferase reporter assay in the human HEK293T cells co-transfected with full length human LXR£] expression vector. The 25,25-difluoro-27-norcholestenoic acid was an inverse agonist and antagonist similar to its non-fluorinated analogue while its reduced derivative 25,25-difluoro-27-norcholest-5-ene-3b,26-diol was an agonist. Molecular dynamics simulation of the ligand-receptor complexes showed that the difluoroacid disrupted the His435-Trp457 interaction although the resulting conformational changes were different from those induced by the non-fluorinated analogue. In the case of the difluoroalcohol, the fluorine atoms actively participated in the interaction with several residues in the ligand binding pocket leading to a stabilization of the active receptor conformation","palabras_clave":"oxiesteroles|lxr|molecular modelling"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7936,"idioma_id":4,"titulo":"Evaluation of an automated chemiluminescent immunoassay for salivary cortisol measurement. Utility in the diagnosis of Cushing's syndrome","resumen":"The aim of the current study was to validate an automated chemiluminescent immunoassay for cortisol quantification in saliva and to determine the cut-off level for Cushing´s Syndrome diagnosis in an adult population. The salivary cortisol levels from healthy individuals and patients previously diagnosed with Cushing´s Syndrome were measured with Siemens Immulite 2000 ® automatic chemiluminescent enzyme-immunoassay analyser with a brief modification. The limit of quantification was 3,4 nmol\/L. The assay also demonstrated a high level of accuracy, as determined by linearity under dilution and recovery tests. Using this methodology, levels higher than 5.7 nmol\/L is indicative of Cushing´s Syndrome with a diagnostic sensitivity and specificity of 90,5% and 97.4% respectively. The assay validated in the present study could be used in the clinical laboratories for the evaluation of cortisol levels in patients in which Cushing´s Syndrome is suspected.","palabras_clave":"CORTISOL|CUSHING|SALIVA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7943,"idioma_id":5,"titulo":"Adultos mayores comunicación y salud (avances)","resumen":"En los próximos años, el porcentaje de adultos mayores crecerá; por ello, resulta fundamental la producción de conocimientos acerca de este grupo etario, el cual, también, resulta vulnerable. el lenguaje es una de las herramientas más importantes en tanto preserva y aumenta la red de relaciones sociales y de comunicación. Se busca describir las características comunicativo-lingüística de adultos mayores que cursan un proceso de envejecimiento normal en un establecimiento geriátrico de Rosario e identificar señales de posibles trastornos en el lenguaje. Se intenta, asimismo, promover la comunicación de los adultos mayores como así también favorecer la reacción de espacios interdisciplinarios que la propicien","palabras_clave":"ADULTO|MAYOR|ENVEJECIMIENTO|COMUNICACIÒN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":7969,"idioma_id":4,"titulo":"Wnt\/&beta;-catenin pathway in the prefrontal cortex is required for cocaine-induced neuroadaptations","resumen":"Behavioral sensitization is a progressive and enduring enhancement of the motor stimulant effects elicited by repeated administration of drugs of abuse. It can be divided into two distinct temporal and anatomical domains, termed initiation and expression, which are characterized by specific molecular and neurochemical changes. This study examines the role of the Wnt canonical pathway mediating the induction of cocaine sensitization. We found that &#946;-catenin levels in the prefrontal cortex (PFC), amygdala (Amyg) and dorsal striatum (CPu) are decreased in animals that show sensitization. Accordingly, GSK3&#946; activity levels are increased in the same areas. Moreover, &#946;-catenin levels in nuclear fraction, mRNA expression of Axin2 and Wnt7b are decreased in the PFC of sensitized animals. Then, in order to demonstrate that changes in the PFC are crucial for initiation of sensitization, we either rescue &#946;-catenin levels with a systemic treatment of a GSK3&#946; inhibitor (Lithium Chloride) or inhibit Wnt\/&#946;-catenin pathway with an intracerebral infusion of Sulindac before each cocaine injection. As expected, rescuing &#946;-catenin levels in the PFC as well as CPu and Amyg blocks cocaine-induced sensitization, while decreasing &#946;-catenin levels exclusively in the PFC exacerbates it. Therefore, our results demonstrate a new role for the Wnt\/&#946;-catenin pathway as a required neuroadaptation in inducing behavioral sensitization.","palabras_clave":"COCAINE NEUROADAPTATIONS|PREFRONTAL CORTEX|SENSITIZATION|WNT CANONICAL PATHWAY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8007,"idioma_id":5,"titulo":"Epistemología de la Psicología en Leonardo Castellani. Raíces Filosóficas y el Problema del Método.","resumen":"El Presbítero Leonardo Castellani desarrolló ?a la par de una obra literaria, educativa, filosófica y periodística abundante- una labor investigativa de relevancia en la psicología argentina. Su importancia en la historia de esta ciencia en el mencionado país, viene siendo demostrada por diversos estudios en las últimas décadas. El objetivo del presente trabajo es aportar nuevos datos acerca de la actuación de nuestro autor en una época en que la psicología en Argentina pugnaba por legitimarse. En el marco de este proceso de legitimación resulta relevante analizar la contribución que realiza Castellani a las discusiones epistemológicas, metodológicas e históricas que se plantean con fuerza en el escenario académico y científico argentino consagrado a la psicología. Su contribución resulta original y podría significar un aporte en la comprensión filosófico-crítica del surgimiento y configuración epistemológica y metodológica de la psicología científica.","palabras_clave":"CASTELLANI|PSICOLOGÍA|EPISTEOLOGÍA|MÉTODO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8012,"idioma_id":4,"titulo":"High class-imbalance in pre-miRNA prediction: a novel approach based on deepSOM (IF 1.438)","resumen":"The computational prediction of novel microRNA within a full genome involves identifying sequences having the highest chance of being a miRNA precursor (pre-miRNA). These sequences are usually named candidates to miRNA. The well-known pre-miRNAs are usually only a few in comparison to the hundreds of thousands of potential candidates to miRNA that have to be analyzed, which makes this task a high class-imbalance classification problem. The classical way of approaching it has been training a binary classifier in a supervised manner, using well-known pre-miRNAs as positive class and artificially defining the negative class. However, although the selection of positive labeled examples is straightforward, it is very difficult to build a set of negative examples in order to obtain a good set of training samples for a supervised method. In this work, we propose a novel and effective way of approaching this problem using machine learning, without the definition of negative examples. The proposal is based on clustering unlabeled sequences of a genome together with well-known miRNA precursors for the organism under study, which allows for the quick identification of the best candidates to miRNA as those sequences clustered with known precursors. Furthermore, we propose a deep model to overcome the problem of having very few positive class labels. They are always maintained in the deep levels as positive class while less likely pre-miRNA sequences are filtered level after level. Our approach has been compared with other methods for pre-miRNAs prediction in several species, showing effective predictivity of novel miRNAs. Additionally, we will show that our approach has a lower training time and allows for a better graphical navegability and interpretation of the results. A web-demo interface to try deepSOM is available at http:\/\/fich.unl.edu.ar\/sinc\/web-demo\/deepsom\/","palabras_clave":"Unsupervised learning|classification|high class-imbalance|deep self-organizing maps"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8022,"idioma_id":5,"titulo":"DRENAJE  Y  TRANSPORTE  VERTICAL  DE  HERBICIDAS  EN  DOS  MOLISOLES  DE  LA  PAMPA ONDULADA ARGENTINA","resumen":"El objetivo del trabajo fue evaluar la dinámica del drenaje de agua y la pérdida por transporte vertical de glifosato, atrazina y acetoclor en dos suelos de textura diferente cultivados con una rotación maíz-soja bajo siembra directa. Se utilizaron seis lisímetros (3,3 x 3,3 m x 1,2 m de profundidad) rellenados con un Hapludol típico (serie Junín) y un Argiudol típico (serie Pergamino). Las dosis de aplicación fueron de 3 a 7 L ha-1 para glifosato (48% p.a.) entre 2006 y 2012, 2 L ha-1 para atrazina (50% p.a.) en 2009 y 2,5 y 3 L ha-1 para acetoclor (84% p.a.) en 2003. Desde 2006, se midió el volumen de agua drenada después de cada lluvia y se determinó la concentración media de herbicidas considerando 13 periodos separados por ocupación (cultivo y barbecho) y momento de aplicación del herbicida. Si bien no hubo diferencias en el drenaje acumulado entre suelos para 2001-2012, existieron diferencias cuando se analizaron periodos de tiempo más cortos, registrándose pulsos de drenaje diferentes (flujo masal y preferencial) asociados a la textura y a las condiciones humedad. Cuando hubo detección de glifosato y AMPA, los drenajes del suelo Hapludol típico fueron 20 veces más concentrados en glifosato y contuvieron 75 veces más cantidad de AMPA que en el suelo Argiudol típico debido a su menor volumen. La atrazina fue detectada en todos los drenajes hasta 3 años después de su aplicación mientras que el acetoclor fue detectado hasta 9 años posteriores a la última aplicación. Estos resultados generan interrogantes acerca del posible aumento del riesgo de contaminación del agua subterránea por el aumento de las dosis de glifosato y por la detección de atrazina y acetoclor, varios años después de su última aplicación.","palabras_clave":"glifosato|atrazina|acetoclor|lisímetros"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8023,"idioma_id":4,"titulo":"Neonatal experiences with ethanol intoxication modify respiratory and thermoregulatory plasticity and affect subsequent ethanol intake in rats","resumen":"Different studies have focused on the deleterious consequences of binge-like or chronic exposure to ethanol during the brain growth spurt period (third human gestational trimester) that in the rat corresponds to postnatal days (PDs) 3&ndash;10. The present study analyzed behavioral and physiological disruptions caused by relatively brief binge-like exposures (PDs 3, 5, and 7) with an ethanol dose lower (3.0 g\/kg) than those frequently employed to examine teratological effects during this stage in development. At PD 9, pups were exposed to ethanol doses ranging between.0&ndash;3.0 g\/kg and tested in terms of breathing patterns and thermoregulation. At PDs 11 and 12, ethanol intake was examined. The main findings were as follows: i) pre-exposure to the drug resulted in brief depressions in breathing frequencies and an exacerbated predisposition toward apneic episodes; ii) these effects were not dependent upon thermoregulatory alterations; iii) early ethanol treatment increased initial consumption of the drug which also caused a marked hypothermia that appeared to regulate a subsequent decrement in ethanol consumption; and iv) ethanol exposure retarded overall body growth and even one exposure to the drug (PD 9) was sufficient to reduce brain weights although there were no indications of microcephaly. In conjunction with studies performed during the late gestational period in the rat, the results indicate that relatively brief binge-like episodes during a critical window of brain vulnerability disrupts the respiratory network and exacerbates initial acceptance of the drug. In addition, ethanol treatments were not found to induce tolerance relative to respiratory and thermal disruptions.","palabras_clave":"neonate|early ethanol intoxication|breathing disruptions|thermoregulation|ethanol|intake rat"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8026,"idioma_id":5,"titulo":"Alcanos en cultivares comerciales de ?festuca alta? [Lolium arundinaceum (Schreb.) Darbysh.]","resumen":"Los n-alcanos son hidrocarburos de cadena lineal que componen la cera de la cutícula de las plantas y participan en numerosas funciones vitales. El contenido relativo de n-alcanos impares con diferente longitud de cadena de carbonos (patrón de alcanos) varía entre especies, cultivares y partes de planta, permitiendo su uso como marcadores naturales de composición de la dieta en estudios de herbivoría. Se analizó el contenido individual de los n-alcanos impares desde C23 hasta C35 en 12 cultivares (cvs) comerciales de festuca alta [Lolium arundinacea (Schreb.) Darbysh.], 10 continentales y 2 mediterráneos (?Arizona? y ?Flecha?). El contenido total (mg\/kg MS) de n-alcanos impares en los cvs fue, en orden creciente, ?Arizona? (369), ?FesCon3?, ?FesCon2?, ?AxL?, ?FesCon4?, ?Royal Q 100?, ?Flecha? (600 a 750) y ?Taita?, ?FesCon1?, ?Malma?, ?GFL 200? y ?GFL 201? (800 a 850). Los n-alcanos más abundantes en los cvs continentales fueron C31 (51±3%), C29 (25±2%) y C33 (14±2%), pero los cvs mediterráneos se diferenciaron marcadamente de los continentales y también entre ellos, ?Arizona? tuvo menos C29 (20%) y más C33 (29%) mientras que ?Flecha? tuvo más C29 (43%) y menos C33 (5%). Los cvs ?Arizona? y ?Flecha? tuvieron los patrones de alcanos más diferentes, lo que permitiría aplicar el método de los alcanos para estimar la proporción de estos cvs en la dieta de animales en pastoreo.","palabras_clave":"alcanos|festuca|cultivares comerciales|seleccion forrajera"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8035,"idioma_id":4,"titulo":"Formulation and Characterization of Polysaccharide Microparticles for Pulmonary Delivery of Sodium Cromoglycate","resumen":"Sodium cromoglycate (SC) is an antiasthmatic and antiallergenic drug commonly used for chronic inhalation therapy; however, many daily intakes are required due to the fast drug clearance from airways. For these reasons, SC polymeric particles for inhalatory administration with adequate aerosolization and mucoadhesive properties were designed to prolong the drug residence time in the site of action. Sodium carboxymethylcellulose (CMCNa), sodium hyaluronate, and sodium alginate were selected to co-process SC by spray drying. The influence of these polysaccharides on the spray drying process and powder quality was evaluated (among others, morphology, size, moisture content, hygroscopicity, flowability, densities, liquid sorption, and stability). In vitro aerosolization, drug release, and mucoadhesion performance were also studied. Particularly, a novel method to comparatively evaluate the interaction between formulations and mucin solution (mucoadhesion test) was proposed as a rapid methodology to measure adhesion properties of inhalable particles, being the results as indicative of clearance probability. Among all the studied formulations, the powder based on SC and CMCNa exhibited the best mucoadhesion and aerosolization performance, the highest process yield and adequate moisture content, hygroscopicity, and stability. SC-CMCNa formulation arose as a promising inhalatory system to reduce the daily intakes and to increase the patient compliance.","palabras_clave":"inhaled particles|spray drying|polysaccharides; |mucoadhesion"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8125,"idioma_id":4,"titulo":"THE FIRST EVIDENCE OF OSTEOMYELITIS IN A SAUROPOD (DINOSAURIA: SAURISCHIA)","resumen":"Osteomyelitis is reported for the first time in a sauropod dinosaur. The material (MCS-PV 183) comes from the Anacleto Formation (Campanian, Late Cretaceous), at the Cinco Saltos locality, Río Negro Province, Argentina. The specimen consists of 16 mid and mid-distal caudal vertebrae of a titanosaur sauropod. Evidence of bacterial infection is preserved in all of these vertebrae. The main anomalies are as follows: irregular ?microbubbly? texture of bone surfaces produced by periosteal reactive bone, abscesses on the rims of the anterior articular surfaces of two centra, numerous pits on centra anterior articulation surfaces, erosions on the anterior articulation of the vertebral centra, a vertical groove in posterior articular face of all the centra and disruption of the prezygapophysis and postzygapophysis (mainly the articular face) from the vertebra 19 and beyond. The last anomaly is increasingly pronounced in more distal elements of the series. Thin sections reveal that the anomalous cortical tissue is composed of avascular and highly fibrous bone matrix. The fibres of the bone matrix are organized into thick bundles oriented in different directions. Both morphological and histological abnormalities in the MCS-PV 183 specimen are pathognomonic for osteomyelitis.","palabras_clave":"OSTEOMYELITIS|SAUROPOD|TITANOSAUR|HISTOLOGY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8159,"idioma_id":5,"titulo":"Micromorfología y estructura de los frutos en Bulbostylis (Cyperaceae) y su valor sistemático en las  especies de América austral","resumen":"Resumen: El género Bulbostylis Kunth incluye aproximadamente 150 especies que habitan zonastropicales y subtropicales en todo el mundo. En Bulbostylis, al igual que en otros géneros de Ciperáceas,la exomorfología de los frutos es uno de los caracteres más estables para la clasificación infragenérica.En este trabajo se dan a conocer la micromorfología y estructura de los frutos de Bulbostylis paraveinte especies de América Austral, representadas en Argentina, Brasil (Paraná, Santa Catarina y RioGrande do Sul), Chile, Paraguay y Uruguay. En base a estudios con microscopía óptica y electrónica debarrido se proponen agrupamientos, teniendo en cuenta la micromorfología de los aquenios así comola presencia y tipo de silicofitolitos. También se realizan microanálisis químicos de los frutos con EDX\/MEB. Se actualiza el sistema de descripción basado en caracteres exomorfológicos, aplicable a frutosy semillas.","palabras_clave":"Bulbostylis|Cyperaceae|micromorfología|EDX\/MEB"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8163,"idioma_id":4,"titulo":"Antifungal susceptibility testing of Malassezia yeast: comparison of two different methodologies","resumen":"All Malassezia species are lipophilic; thus, modifications are required in susceptibility testing methods to ensure their growth. Antifungal susceptibility of Malassezia species using agar and broth dilution methods has been studied. Currently, few tests using disc diffusion methods are being performed. The aim was to evaluate the in vitro susceptibility of Malassezia yeast against antifungal agents using broth microdilution and disc diffusion methods, then to compare both methodologies. Fifty Malassezia isolates were studied. Microdilution method was performed as described in reference document and agar diffusion test was performed using antifungal tablets and discs. To support growth, culture media were supplemented. To correlate methods, linear regression analysis and categorical agreement was determined. The strongest linear association was observed for fluconazole and miconazole. The highest agreement between both methods was observed for itraconazole and voriconazole and the lowest for amphotericin B and fluconazole. Although modifications made to disc diffusion method allowed to obtain susceptibility data for Malassezia yeast, variables cannot be associated through a linear correlation model, indicating that inhibition zone values cannot predict MIC value. According to the results, disc diffusion assay may not represent an alternative to determine antifungal susceptibility of Malassezia yeast.","palabras_clave":"Microdilusión|Difusión en agar|Malassezia"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8172,"idioma_id":4,"titulo":"Gene polymorphism profiles of drug-metabolising enzymes GSTM1, GSTT1 and GSTP1 in an Argentinian population","resumen":"Background: Glutathione S-transferases (GSTs) are drug-metabolizing enzymes involved in biotransformation of carcinogens, drugs, xenobiotics and oxygen free radicals. Polymorphisms of GST genes contribute to inter-individual and population variability in the susceptibility to environmental risk factors, cancer predisposition and pharmacotherapy responses. However, data about GST variability in Argentina are lacking.Aim: The purpose was to determine the prevalence of GSTM1, GSTT1 and GSTP1 polymorphisms the general population from a central region of Argentina and to perform inter-population comparisons. Subjects and Methods: GSTM1 and GSTT1 gene deletions and GSTP1 c.313A>G were genotyped by PCR assays in 609 healthy and unrelated Argentineans.Results: The frequencies of variant genotypes in Argentineans were GSTM1-null (45%), GSTT1-null (17%) and GSTP1-GG (11%). GSTM1-positive genotype was significantly associated with GSTP1-AG or GSTP1-GG variants (p=0.037; p=0.034, respectively). Comparison with worldwide populations demonstrated that the GST distributions in Argentina are similar to those reported for Italy and Spain, whereas significant differences were observed regarding Asian and African populations (p<0.001).Conclusion: We have determined for the first time the normative profile of three pharmacogenetically relevant polymorphisms (GSTM1, GSTT1 and GSTP1) in the largest Argentinean cohort described to date, providing the basis for further epidemiological and pharmacogenetic studies in our country.","palabras_clave":"ARGENTINIAN POPULATION|GLUTATHIONE S-TRANSFERASES|HUMAN VARIABILITY|PHARMACOGENETIC MARKERS|POLYMORPHISMS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8187,"idioma_id":4,"titulo":"Improving Scientific Application Execution on Android Mobile Devices via Code Refactorings (Indexed SCI, IF JCR2015=0.652)","resumen":"The increasing number of mobile devices with ever-growing capabilities makes them useful for running scientific applications. However, these applications have high computational demands, whereas mobile devices have limited capabilities when compared to non-mobile devices. More importantly, mobile devices rely on batteries for their power supply. We initially measure the battery consumption of different versions of known micro-benchmarks representing common programming primitives found in scientific applications. Then, we analyze the performance of such micro-benchmarks in CPU-intensive mobile applications. We apply good programming practices and code refactorings to reduce battery consumption of scientific mobile applications. Our results show the reduction in energy usage from applying these refactorings to three scientific applications, and we consequently propose guidelines for High Performance Computing (HPC) applications. Our focus is on Android, the dominant mobile operating system. As a long-term contribution, our results represent one more step in the progress towards hybrid distributed infrastructures comprising fixed and mobile nodes, i.e., the so-called Mobile Grids.","palabras_clave":"SMARTPHONES|ANDROID|SCIENTIFIC COMPUTING|COMPUTATIONAL KERNELS|REFACTORING"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8203,"idioma_id":4,"titulo":"Sexual dimorphism in the shell of a nassariid gastropod. A 3d geometric 3 morphometrics approach","resumen":"Among gastropods, dimorphism is reported in shell size, radular characteristics, and lesser extent in shell shape. The relationship of dimorphic characters of the shell with spawning is scarcely studied in literature. Buccinanops globulosus is an interesting model to study sexual dimorphism in shell shape, because the adults attached their egg capsules to the females? own shells (callus zone). Our hypothesis is that the shell dimorphism is evidenced in the form (size and shape) of callus zones of females shell, compared to males one. In order to test this hypothesis we use a 3D geometric morphometrics (GM) method with several advantages over 2D GM. The relationship between callus shape and size was allometric. During growth, the main callus shape changes are related to the mean size increment, which is more evident in larger females. These callus zones are characteristically slender in males and small females, and more inflated in large females. Our analyses revealed that female shells are different from male ones and those differences are significant on the callus zone where the egg capsules are attached by the female. This finding suggests a relationship of the shell form with spawning. Our findings are not only relevant in terms of the shell dimorphism of the particular spawning substrate area (callus zones) and its reproductive implications, but also provide insights into the evaluation of shell shape variation on areas without type I or II anatomical landmarks in 3D GM.","palabras_clave":"GEOMETRIC MORFOMETRICS 3D|BUCCINANOPS|SPAWN|SHELL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8233,"idioma_id":4,"titulo":"Intersex and liver alterations induced by long-term sublethal exposure to 17&#945;-ethinylestradiol in adult male Cnesterodon decemmaculatus (Pisces, Poeciliidae)","resumen":"The aim of the present study was to assess the responses of the gonopodium morphology and the gonadal and liver histology of adult male Cnesterodon decemmaculatus to sublethal long-term exposure concentrations of 17?¿-ethinylestradiol (EE2). Two experiments were conducted exposing the fish to waterborne concentrations of EE2 ranging from 20ng\/L to 200ng\/L for 8wk, 12wk, and 16wk. Intersex gonads were observed after 8wk and 16wk in fish exposed to 200ng EE2\/L and 100ng EE2\/L, respectively. Oocytes?L development from testis germ cells and replacement of the efferent duct periodic acid-Schiff-positive secretion surrounding spermatozeugmata by parenchymal tissue and duct structure alterations were the major observed changes in the gonads. In contrast, no response was observed in the gonopodium morphology. Liver histology was also altered, showing increasing steatosis, single-cell necrosis to generalized necrosis, and disruption of acinar organization from 100ng EE2\/L to 200ng EE2\/L. In summary, the present results showed that although EE2 was not able to alter the morphology of a developed gonopodium, it was capable of inducing development of testicular oocytes in adult male C. decemmaculatus at environmentally relevant concentrations. Thus, externally normal but intersex C. decemmaculatus males would be expected in the wastewater-receiving streams that the species inhabits. According to the literature, the present study would be the first indicating estrogen-induced intersex in adult male poeciliid.","palabras_clave":"ECOTOXICOLOGY|ESTROGENIC COMPOUNDS|TESTIS-OVA|HEPATOTOXICITY|CNESTERODON DECENMACULATUS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8270,"idioma_id":4,"titulo":"Genetic population structure of the long-tailed pygmy rice rat (Rodentia, Cricetidae) at different geographic scales in the Argentinean Patagonia","resumen":"The population genetic structure of Oligoryzomys longicaudatus colilargo was examined at two geographical scales: (a) regional, including five populations of the Argentinean Patagonia separated by 60?315 km and (b) landscape scale, using five populations from different valleys of the locality of Cholila in the subantarctic forest separated by 6?27 km, and a nearby locality of the Patagonian steppe, with an average distance from Cholila of 33 km. Eight microsatellite loci specific for O. longicaudatus were used as genetic markers. At the regional scale, four genetic clusters were detected by the Geneland software. The genetic structure was found to follow a latitudinal pattern. This result was supported by the FST statistic, indicating low levels of current gene flow within the region. At the landscape level, genetic differentiation among the five populations was also found. Estimated migration rates were, in general, low and asymmetrical between nearby populations. Using a causal modeling approach, we detected that the combination of landscape features such as lakes, rivers, urban settlements and roads appear to constrain the dispersal of O. longicaudatus at this scale. This result would explain why nearby populations were so different in their genetic composition. The information about geographic features limiting rodent dispersal provided here could help to design more accurate prevention measures against the expansion of hantavirus pulmonary syndrome.","palabras_clave":"Oligoryzomys longicaudatus|regional genetic structure|Argentinean Patagonia|landscape genetics"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8281,"idioma_id":4,"titulo":"Protozoa stimulate the plant beneficial activity of rhizospheric pseudomonads","resumen":"AimsThe functioning of plant-associated bacteria is strongly influenced by their interaction with other organisms. For instance, bacteria upregulate the production of secondary metabolites in presence of protozoa and we hypothesised that this interaction may contribute to plant health.MethodsHere, we tested if the effect of beneficial pseudomonads on wheat growth and health is modified by co-inoculation with the bacterivorous amoeba Acanthamoeba castellanii. We assessed effects of this co-inoculation in absence and presence of the root pathogen Pythium ultimum.ResultsIn absence of amoebae, bacterial isolates had few beneficial effects and some isolates exacerbated growth inhibition by the pathogen (despite their reported beneficial effects in vitro). Effects on plant growth in absence and presence of the pathogen were negatively correlated. Co-inoculation with amoebae suppressed this relationship, leading to plant growth promotion in absence and reduction of deleterious effects in presence of the pathogen. The positive effect of amoebae in absence of the pathogen could be related to bacterial siderophore production in vitro.ConclusionsOur results illustrate the discrepancy between in vitro and in vivo effects of plant beneficial bacteria. Incorporation of other rhizospheric trophic components such as protists may be a key factor to influence the plant-beneficial potential of bacteria in vivo.","palabras_clave":"Protozoa|Rhizosphere|disease suppression|Plant growth promotion|Pseudomonas|wheat"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8291,"idioma_id":4,"titulo":"Global-change drivers of ecosystem functioning modulated by natural variability and saturating responses","resumen":"Humans are altering global environment at an unprecedented rate through changes in biodiversity, climate, nitrogen cycle, and land use. To address their effects on ecosystem functioning, experiments most frequently explore one driver at a time and control as many confounding factors as possible. Yet, which driver exerts the largest influence on ecosystem functioning and whether their relative importance changes among systems remain unclear. We analyzed experiments in the Patagonian steppe that evaluated the aboveground net primary production (ANPP) response to manipulated gradients of species richness, precipitation, temperature, nitrogen fertilization (N), and grazing intensity. We compared the effect on ANPP relative to ambient conditions considering intensity and direction of manipulations for each driver. The ranking of responses to drivers with comparable manipulation intensity was as follows: biodiversity>grazing>precipitation>N. For a similar intensity of manipulation, the effect of biodiversity loss was 4.0, 3.6, and 1.5, times larger than N deposition, decreased precipitation, and increased grazing intensity. We interpreted our results considering two hypotheses. First, the response of ANPP to changes in precipitation and biodiversity is saturating, so we expected larger effects when the driver was reduced, relative to ambient conditions, than when it was increased. Experimental manipulations that reduced ambient levels had larger effects than those that increased them. Second, the sensitivity of ANPP to each driver is inversely related to the natural variability of the driver. In Patagonia, the ranking of natural variability of drivers is as follows: precipitation>grazing>temperature>biodiversity>N. So, in general, the ecosystem was most sensitive to drivers that varied the least. Comparable results from Cedar Creek (MN) support both hypotheses and suggest that sensitivity to drivers varies among ecosystem types. Given the importance of understanding ecosystem sensitivity to predict global-change impacts, it is necessary to design new experiments located in regions with contrasting natural variability and that include the full range of drivers.","palabras_clave":"Sensibilidad ecológica|Pérdida de biodiversidad|Cambio climático|Deposición de Nitrógeno"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8295,"idioma_id":5,"titulo":"Células T helper foliculares en sangre periférica de pacientes con artritis reumatoidea","resumen":"Introducción: La artritis reumatoidea (AR) es una enfermedad autoinmune y crónica caracterizada por lapresencia de autoanticuerpos como factor reumatoide (FR) y anticuerpos antiproteínas citrulinadas. Unapoblación de células T helper foliculares (Tfh), que expresan CD4+CXCR5+, colabora con las células B parala producción de anticuerpos. La expresión diferencial de CXCR3 y CCR6 dentro de las células CD4+CXCR5+define 3 subpoblaciones mayores: CXCR3+CCR6&#8722; (Tfh1), CXCR3-CCR6&#8722; (Tfh2) y CXCR3-CCR6+ (Tfh17). El objetivo del estudio fue evaluar si existe asociación entre el porcentaje de estas células y la AR, y lacorrelación de las mismas con actividad de la enfermedad.Material y métodos: Participaron 24 pacientes con AR, 22 controles saludables (CS) y 16 pacientes con artritisindiferenciada (AI). Los porcentajes de las células CD4+CXCR5+ y sus subpoblaciones fueron analizadospor citometría de flujo.Resultados: No hubo diferencias en los porcentajes de células CD4+CXCR5+ entre los pacientes con ARy CS o entre AR y AI. Tampoco en las subpoblaciones Tfh1, Tfh2 y Tfh17. No hubo correlación entre lascélulas T CD4+CXCR5+, Tfh1, Tfh2 y Tfh17 y el«Disease Activity Score in twenty-eigth joints»(DAS28),así como tampoco con la velocidad de sedimentación globular. Sorpresivamente, hubo una correlaciónpositiva entre las células Tfh17 y la proteína C reactiva. Finalmente, no hubo correlación entre las célulasTCD4+CXCR5+ o cualquiera de las subpoblaciones y antivimentina mutada citrulinada así como tampocoentre dichas células y el FR.Conclusión: No se hallaron diferencias entre los porcentajes de las células T CD4+CXCR5+ y sus subpoblacionesen sangre periférica de los pacientes con AR y las células de los grupos controles. Esto no descartaun papel patogénico de estas células en el desarrollo y actividad de la AR.","palabras_clave":"artritis reumatoidea|inmunopatogenesis|celulas T helper foliculates"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8296,"idioma_id":4,"titulo":"Combining ZVI reduction with photo-Fenton process for the removal of persistent pollutants","resumen":"An iron-based photochemical process able to act via reductive and oxidative stages by tuning experimental conditionshas been explored. In a first step, zero-valent iron (ZVI), added as steel wool, was used to reduce those pollutants reluctant to oxidative processes. Then, the iron released in the solution was employed, upon addition of hydrogen peroxide, to drive a photo-Fenton process. This procedure has been checked with a mixture of five chemicals, namely p-toluensulfonic acid, benzoic acid, p-nitrobenzoic acid, acetaminophen and caffeic. P-nitrobenzoic acid resulted to be the most reluctant against oxidation but it was reduced in the absence of H2O2 to form 4-aminobenzoic acid; the presence of salts (e.g. tap water) was required and best results were reached at neutral pH.As p-aminobenzoic acid can be more easily oxidized than p-nitrobenzoic,combination of both stages is meaningful: a ZVI-based reduction followed by a photo-Fenton like-oxidationwas employed to remove this pollutant from tested solutions.","palabras_clave":"iron|ZVI|photo-Fenton|wastewater|combined processes"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8299,"idioma_id":4,"titulo":"Mechanical and corrosion behavior of thick and soft DLC coatings. Surface and Coatings Technology","resumen":"The DLC coatings are chemically inert, have low friction coefficient and good wear resistance. Depending on H content and sp3 bonds, they can be classified in ?soft? or ?hard? films. In this work, the corrosion and mechanical behavior, as well as the adhesion of thick DLC coatings are studied. The coatings, which are in fact silicon containing amorphous hydrogenated carbon films, were deposited by PACVD on nitrided austenitic stainless steel (duplex sample) and non nitrided austenitic stainless steel (coated sample). The films were characterized by EDS and Raman spectroscopy, hardness was assessed by nanoindentation and microstructure was analyzed by OM and SEM. To evaluate sliding wear behavior and friction, pin on disk tests were performed. The abrasive wear resistance was tested using the ASTM G65-95 Dry Sand\/Rubber Wheel test. Erosion tests were conducted in water and sand flux. The corrosion resistance was evaluated by the Salt Spray Fog Test and electrochemical tests in 3.5 % NaCl solution. The adhesion was tested using Scratch Test. The purpose was to systematically characterize the defects present in these thick DLC coatings relating them to adhesion, wear and corrosion resistance.The thickness of the DLC coating was about 37 &#61549;m, and its hardness was 12 GPa. The coatings presented a low friction coefficient, about 0.09. In the abrasive tests, the mass loss was negligible and in erosion experiments, the mass loss was reduced to 30 %. Regarding the corrosion performance, the behavior in the Salt Spray Fog Test was good only in the duplex samples. In potentiostatic tests in 3.5% NaCl using steps, the current density increased at higher potentials for the duplex sample. Concerning the film adhesion, the critical load was also higher in theses samples than in the coated ones. The nitrided layer was a good interface for reducing the stresses and improving the adhesion, which is relevant for the decrease of the propagation rate of corrosion, when traversing defects are formed in the coating.","palabras_clave":"Thick DLC coatings|Wear|Corrosion|Stainless steel|Adhesion"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8309,"idioma_id":4,"titulo":"17&#946;-Estradiol Protects Skeletal Myoblasts from Apoptosis through P53, BCL-2 and FoxO Families","resumen":"17&#946;-Estradiol (E2) protects several nonreproductive tissues from apoptosis, including skeletal muscle. Previously, we showed that E2 at physiological concentrations prevented apoptosis induced by H2O2 in skeletal myoblasts, reverting PKC&#948;, JNK, and p66Shc activation and exerting a beneficial action over mitochondria. Since genomic actions underlying the regulation of nuclear gene transcription are a common property of this steroid, the present work characterizes the transcriptional activity modulated by E2 to exert its antiapoptotic effect. We report that E2 protects skeletal myoblasts against apoptosis induced by H2O2 modulating p53 and FoxO transcription factors and then their target genes Bcl-2, Bim, Puma, PERP, and MDM2, without affecting Noxa gene. The results presented in this work support the notion that the transcription factors FoxO and p53 coordinate apoptosis in C2C12 cells, and deepens our knowledge about a putative molecular mechanism by which E2 exerts beneficial effects against oxidative stress in skeletal myoblasts. J. Cell. Biochem. 118: 104?115, 2017. © 2016 Wiley Periodicals, Inc.","palabras_clave":"17&#946;-ESTRADIOL |C2C12 MUSCLE CELLS|BCL-2|FOXOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8313,"idioma_id":4,"titulo":"KINETIC ANALYSIS OF THE REGIONAL AGRO-INDUSTRIAL WASTES COMBUSTION","resumen":"Cuyo Region generates a signi&#64257;cant quantity of agro-industrial wastes. To exploit this waste for energy production, a combustor was installed in this region. To improve its design and operation, a kinetic study of six agro-industrial wastes combustion, using thermogravimetric analysis, was made. The results show that this phenomenon occurs in four stages: drying, devolatilization, char combustion and residual combustion. Maximum weight loss occurs during the devolatilization stage, followed by the char combustion.The contraction geometry?s model describes the devolatilization, indicating that the degradation rate is controlled by the resulting reaction interface progress toward the solid center. Moreover, the &#64257;rst order reaction model describes the char combustion stages, showing that the reaction rate is proportional to remaining reactant(s) fraction. The highest energy activation values were obtained for sawdust at heating rate equal to 10 K\/min and plum pits at heating rate equal to 15 K\/min for devolatilization and char combustion, respectively, presenting slower reaction rate and more dif&#64257;culty of a reaction starting.For both analyzed stages, the activation energy values vary slightly with the heating rate. This variation can be due to the kinetic rate being controlled by the occurrence of physical transformation. It does not depend on mass but it depends on temperature..","palabras_clave":"AGRO-INDUSTRIAL WASTE|COMBUSTION|KINETIC MODEL|THERMOGRAVIMETRIC ANALYSIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8351,"idioma_id":4,"titulo":"Characterization of the boundedness of generalized fractional maximal functions and related operators in Orlicz spaces","resumen":"Given $0< alpha<n$ and a Young function $eta$, we consider the generalized fractional maximal operator $M_{alpha,eta}$ defined by[M_{alpha,eta} f(x)=suplimits_{Bi x} |B|^{alpha\/n}||f||_{eta,B},]where the supremum is taken over every ball $B$ contained in $mathbb{R}^n$.In this article, we give necessary and sufficient Dini type conditions on the functions $mathcal{A}$, $mathcal{B}$ and $eta$ such that $M_{alpha,eta}$ is bounded from the Orlicz space $L^{mathcal{A}}(mathbb{R}^n)$ into the Orlicz space $L^{mathcal{B}}(mathbb{R}^n)$. We also present a version of this result for open subsets of $mathbb{R}^n$ with finite measure. Both results generalize those contained in cite{C} and cite{HSV} when $eta(t)=t$, respectively. As a consequence, we obtain a characterization of the functions involved in the boundedness of the higher order commutators of the fractional integral operator with BMO symbols. Moreover, we give sufficient conditions that guarantee the continuity in Orlicz spaces of a large class of fractional integral operators of convolution type with less regular kernels and their commutators, which are controlled by $M_{alpha,eta}$.","palabras_clave":"ORLICZ SPACES|FRACTIONAL MAXIMAL FUNCTIONS|FRACTIONAL INTEGRAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8353,"idioma_id":4,"titulo":"Bacterioplankton cytometric fingerprint and morphotypes structure resemble environmental conditions in a sub-Antarctic peatland","resumen":"Peatland pools usually show a marked gradient regarding their minerotrophic (harder and less acidic waters) versus ombrotrophic (softer and more acidic waters) status, which appears to be crucial in structuring their planktonic food webs. In this study, we analyzed the effect of such habitat diversity in shaping bacterioplankton assemblages. The planktonic bacteria from five pools located in Rancho Hambre peat bog (Tierra del Fuego Island) were studied through morphological and cytometric approaches, over more than one seasonal cycle. The community was always dominated by small cocci with an average cell-size of 0.27 x 0.36 µm. Bacterioplankton morphological structure and cytometric fingerprint were correlated (Mantel test: P <0.001), both methods used to characterize bacterioplankton showed significant differences between minero- and ombrotrophic pools. Variation in bacterial assemblage structure was mainly explained by abiotic variables relevant in peatlands such as pH, total hardness, conductivity, concentration of inorganic nutrients and concentration and quality of dissolved organic carbon. Notably, these relatively fast approaches detected similar landscape-driven ecological patterns as previous high-throughput sequencing molecular studies of prokaryotes from the same pools, promising to be useful screening tools for limnological surveys as well as for monitoring the response of bacterial assemblages to environmental changes in peatland ecosystems.","palabras_clave":"BACTERIOPLANKTON|MORPHOTYPES STRUCTURE|CYTOMETRIC FINGERPRINTING|PEAT BOG POOLS|MINERO\/OMBROTROPHIC STATUS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8390,"idioma_id":4,"titulo":"Lipid Accumulation Product (LAP) and Visceral Adiposity Index (VAI) as Markers of Insulin Resistance and Metabolic Associated Disturbances in Young Argentine Women with Polycystic Ovary Syndrome.","resumen":"Polycystic ovary syndrome (PCOS) is an endocrine disorder. PCOS women are at high risk of developing insulin resistance and cardiovascular disorders since young age. We aimed to study the reliability of lipid accumulation product (LAP) and visceral adiposity index (VAI) as markers of metabolic disturbances (MD) associated with insulin resistance (IR) in young reproductive aged PCOS patients. We also evaluated the association between LAP and VAI and the presence of hyperandrogenism. In a cross-sectional study, 110 PCOS patients and 88 control women (18?35 years old) were recruited. PCOS patients were divided into 2 groups, as hyperandrogenic and non-hyperandrogenic considering the signs of hyperandrogenism (clinical or biochemical).Anthropometric measurements were taken and blood samples collected. Metabolic and anthropometric characteristics and their association with IR and associated MD were evaluated and LAP and VAI were calculated. LAP and VAI were compared with TC\/HDL-c and TG\/HDL-c to define the best markers of MD in this population. Independentlyof the phenotype, young PCOS patients showed high IR and dyslipidemia. Both LAP andVAI showed to be more effective markers to assess MD and IR in these young women than TG\/HDL-c or TC\/HDL-c [cut-off values: LAP: 18.24 (sensitivity: 81.43 % specificity: 73.49 %), positive predictive value (PPV): 75.0 %, negative predictive value (NPV): 77.27 %, VAI: 2.19 (sensitivity: 81.16 % specificity: 72.15 % PPV: 74.65 % NPV: 72.22 %)]. LAP and VAI are representative markers to assess MD associated with IR in young PCOSpatients. All PCOS patients, independently of their androgenic condition, showed high metabolic risk.","palabras_clave":"cardiovascular risk markers |LAP|VAI|PCOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8405,"idioma_id":4,"titulo":"STUDY AND COMPARISON OF DIFFERENT DRYING PROCESSES FOR DEHYDRATION OF RASPBERRIES","resumen":"The aim of the present study was to evaluate and compare different drying methods(microwave, hot air + microwave and osmotic dehydration + microwave) in raspberries(cv. Heritage). A portion of raspberries was pretreated with osmotic dehydration (60ºBrixsucrose solution at 20ºC for 360min) and another with hot air drying (HAD) (1.5m\/s airspeed at 60ºC for 300min). Pretreated raspberries were then dried by microwave and atthree different intensities (3.5W\/g, 7.5W\/g and 11W\/g). Physicochemical properties(moisture content, water activity and drying rate) and quality parameters (opticalproperties, mechanical properties, antioxidant capacity and rehydration capacity) of driedraspberries were evaluated. Results showed that the microwave drying at 7.5W\/g (50 minand final temperature of 79± 5.1°C) allowed a high yield of dried raspberries. Thecombined processes were not efficient to accelerate the decrease of moisture content, dueto the low drying rate of the pretreatments. In terms of quality, none of the dryingprocesses allowed a high retention of the antioxidant capacity. However, they allowed anappropriate rehydration performance. The combination of HAD with microwave dryingDownloaded by [R. H. Mascheroni] at 13:18 04 July 20162allowed obtaining a good appearance and desirable texture on the dried product. Thus,this last option seems to be the best among the drying methods tested, but additionalstudies are required to improve the efficiency of the process and the effect on theantioxidant capacity during drying.","palabras_clave":"RASPBERRIES|COMBINED DRYING|DRYING RATE|QUALITY PARAMETERS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8418,"idioma_id":5,"titulo":"Estudio arqueométricos del registro de clavos procedentes de contextos funerarios de las ruinas de San Francisco (Mendoza).","resumen":"Los elementos metálicos incorporados en los contextos funerarios coloniales ofrecen información que permite establecer cronologías de fabricación y posibles procedencias de las materias primas utilizadas. En este caso, aplicaremos estudios arqueométricos a los materiales de clavazón que formaron parte de los contextos funerarios registrados en las Ruinas de San Francisco (templo Jesuita desde el siglo XVII al XVIII), ubicado en la Ciudad de Mendoza. El objetivo de los estudios fue responder interrogantes relacionados con su proceso de producción (tecnología, manufactura y materias primas comprometidas para su elaboración). Para tal fin, fue importante conocer la distribución espacial y estratigráfica de los elementos de clavazón y su relación contextual con los entierros humanos registrados. De igual manera se establecieron, a partir de análisis metalográficos, las técnicas de producción y cronología de los elementos analizados, lo que permitió también comprobar si existió algún grado de re-utilización de elementos durante el período analizado.","palabras_clave":"Clavo arqueológico|Metalografía|Acero esponjoso|Acero pudelado. eds"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8420,"idioma_id":4,"titulo":"Integrated Application of Enhanced Replacement Method and Ensemble Learning for the Prediction of BCRP\/ABCG2 Substrates","resumen":"Breast Cancer Resistance Protein (BCRP or ABCG2) is a polyspecific efflux-transporter which belongs to the ATP-binding Cassette superfamily. Up-regulation of BCRP is associated to multi-drug resistance in a number of conditions, e.g. cancer and epilepsy. Recent proteomic studies show that high-expression levels of BCRP are found in healthy human intestine and at the blood-brain barrier, limiting the absorption and brain distribution of its substrates. Here, we have jointly applied the Enhanced Replacement Method and ensemble learning approaches to obtain combinations of 2D linear classifiers capable of discriminating among substrates and non-substrates of the wild type human BCRP. The best model ensemble obtained outperforms previously reported 2D linear classifiers, showing the ability of the Enhanced Replacement Method and ensemble learning schemes to optimize the performance of individual models. This is the first report of the Enhanced Replacement Method to solve classification problems.","palabras_clave":"Breast Cancer Resistance Protein|ABC Transporters|ABCG2|Enhanced Replacement Method"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8430,"idioma_id":4,"titulo":"HYDROGEOCHEMISTRY, ISOTOPIC COMPOSITION AND WATER AGE IN THE HYDROLOGIC SYSTEM OF A LARGE CATCHMENT WITHIN A PLAIN HUMID ENVIRONMENT (ARGENTINE PAMPAS): QUEQUÉN GRANDE RIVER, ARGENTINA","resumen":"The Quequen Grande River (QGR) is a large catchment (10,000km2) in the Pampa Plain  in Argentina. From November 2004 until April 2013 a hydrochemical and stable  isotopes monitoring program was conducted, which include three sampling stations of  monthly composite precipitation, weekly samples in two sites along the river, and several groundwater samples A standard data interpretation was initially performed applying standard statistics, Piper  diagrams and &#948;18O vs &#948;2H diagrams. The time evolution of the values of &#948;18O in precipitation and streamwater were also determined. The integration of hydrogeochemistry and stable isotopes data indicates the existence of  three main components of streamflow: 1) Baseflow: characterized by EC from 1200 to  1800 &#956;s\/cm and an isotope composition quite constant around &#948;18O -5.3? and &#948;2H - 33.8?. Water age for groundwater contribution is typically around 30 to 40 years using chlorofluorocarbons (CFCs). 2) Direct runoff: composed of channel interception and overland flow, which is of a low EC in the order of 50 to 100 &#956;s\/cm, and a highly variable isotopic composition; 3) translatory flow (pre event water that is stored within the subsoil ) with an intermediate EC and isotopic composition close to that of the weighted average composition of precipitation The hydrochemical and stable isotopic data allow the differentiation between baseflow and direct runoff. In addition to thus, CFC dating is a useful tool in assessing the dominance of baseflow in a stream. The data lead to a conceptual model in which an intermediate flow system, with mean residence time (MRT) of around 35 years, discharges into the drainage network. A regional flow system (MRT>50 years) discharges to the Ocean. It is concluded that in this large plain catchment streamflow separation, only two components can be applied in: a) short storm precipitation events having a high sampling frequency, b) during long dry periods when pre-event soil water is not released.","palabras_clave":"PAMPA PLAIN|ARGENTINA|ISOTOPE HYDROLOGY|MEAN RESIDENCE TIME|CFCs|NOBLE GASES|STREAM FLOW SEPARATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8657,"idioma_id":4,"titulo":"Sound model for dialogue profiling","resumen":"Zipfian behaviour has been defined as a way to predict word distributions in natural language for written texts. It keeps valid for any Language. This type of simple models, opens a door for practical applications for understanding how the brain works and produce sentences and dialogues in a very efficient and robust way. Currently, many applications make profit of advances in understanding linguistics and psycholinguistics. But those advances have not a similar counterpart in speech and utterances modelling fields. This paper presents a fractal model for oral productions in Spanish. The Results of the analysis show that samples from a sound library with Spanish voices can be assimilated to a specific fractal distribution. Disregarding which is the speaker, the trend keeps valid for every sample. This finding shows that also spoken language performs","palabras_clave":"natural language processing| dialogue processing|fractals|language metrics"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8662,"idioma_id":4,"titulo":"Farming together, learning together, and improving together. A Socio-technical analysis of the development of inter-cooperative fish-farming projects in Argentina","resumen":"Through the second half of the twentieth century, within both developed and underdeveloped countries, several social movements sought to produce technological alternatives in order to encourage the development of environmentally sustainable and socially inclusive dynamics. In last two decades, different international agencies encouraged the development of pro-poor aquaculture projects among small rural producers, in order to reduce poverty. However, in many cases, they exhibit limitations in terms of infrastructure; deficient services; troubles to get supplies and financial sources; and poor organization. Solving these limitations represents a big technological and cognitive challenge, but the public policies implemented were inspired by mainstream models of innovation with poor results. This paper aims to analyse how these key actors, such as cooperatives, can strengthen inclusive innovation and local development processes. It asks the following question: How cooperative rationalities can operate in inclusive innovative dynamics?","palabras_clave":"Sistemas de innovación|Modelo interactivo inter-actoral|Innovación Inclusiva|Piscicultura"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8694,"idioma_id":10,"titulo":"'Tradición funcional, racionalidad técnica y valor estético. Molinos y silos cerealeros en la Pampa Húmeda argentina'","resumen":"      A metáfora do 'celeiro  do mundo', definida a Argentina por  um longo período, dada a sua incorporação na divisão internacional do trabalho como um  fornecedor de grãos, carnee produtos alimentares. A metáforaestava presente nos artefatos  necessários para cumprir esse  papel. Hoje, o significadodesses artefatos foi interrompido,  transcendendo a avaliação funcional eeconômica para se transformar objetos  estéticos. Este artigo analisa o  significado no trabalho de artistas  e arquitetos que marcaram esse  processo, buscando interpretar como  ele adquiriu a avaliação atualdessas formas.  ","palabras_clave":"FUNCIONALIDADE|TECNOLOGIA|BELEZA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8752,"idioma_id":5,"titulo":"Tras el rastro del voto estratégico en el primer balotaje de Argentina: análisis comparativo de la asociación entre los resultados de la primera y segunda vuelta electoral a nivel mesa de votación","resumen":"En octubre de 2015 se realizaron las elecciones presidenciales argentinas. Ninguno de los candidatos consiguió la cantidad de votos suficiente para ser proclamado presidente, lo cual definió un escenario de balotaje entre los dos más votados. Mientras tanto, más de la cuarta parte del electorado votó por un candidato que no alcanzó a pasar a la segunda vuelta. En este trabajo se investiga como este electorado, y el conformado por quienes votaron en blanco o cuyo voto fue anulado, votó en el primer balotaje realizado en Argentina. Mediante análisis de regresión lineal múltiple, se estudia la asociación entre el voto en primera vuelta de este electorado y el voto por alguno de los dos candidatos en el balotaje. La unidad de análisis es la mesa de sufragio, la menor unidad de agregación posible. Los análisis se hacen a nivel nacional, regional y por nivel educativo.","palabras_clave":"Balotaje|Trasvase de votos|Regresion|Comportamiento electoral"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8762,"idioma_id":4,"titulo":"Interpretation and decoherence: a contribution to the debate Vasallo & Ensfeld vs Crull","resumen":"The discussions 'decoherence versus interpretation' revolve around whether the theory of decoherence requires interpretive considerations or not to solve the measurement problem. In general, those discussions take the theory of decoherence for granted, as if it would not involve any difficulty. Therefore, they use to focus on the 'interpretation' wing: even in the case that the open system decoheres in a given basis, the whole closed system is still in a superposition and, thus, without an adequate interpretation it cannot be said that the observables defined by that basis behave classically. In the present paper we focus on the 'decoherence' wing: given the conceptual challenges that the theory must face and the approaches alternative to the orthodox view, the understanding of the phenomenon of decoherence in itself still requires a great deal of interpretive work.","palabras_clave":"Quantum mechanics|Decoherence |Interpretation|Reduced state"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8781,"idioma_id":4,"titulo":"Cutaneous Human Papillomavirus genotypes in different kinds of skin lesions in  Argentina","resumen":"Cutaneous human papillomaviruses (HPVs) comprise a large and highly heterogeneous virus group. Some of the cutaneous HPVs of the genus Beta have been suggested as a co-factor in the development of non-melanoma skin cancer (NMSC). The aim of this study was to determine cutaneous HPV prevalence and type-specific distribution in different kinds of skin lesions from Argentine patients visiting Dermatology Departments of three hospitals from Buenos Aires. A cross-sectional analysis was performed. HPV DNA was analyzed in (i) 3 patients with Epidermodysplasia verruciformis (EV) harboring benign lesions (BL) (n&#8201;=&#8201;1) and squamous cell carcinoma (SCC) (n&#8201;=&#8201;4); (ii) 240 non-EV patients harboring: (a) BL (n&#8201;=&#8201;38), (b) Actinic Keratosis (AK) (n&#8201;=&#8201;83), (c) SCC (n&#8201;=&#8201;74), and (d) basal cell carcinoma (BCC) (n&#8201;=&#8201;96). Detection and genotyping of 35 cutaneous HPV DNA was carried out by BGC-PCR and GP5+\/6&#8201;+&#8201;PCR followed by reverse line blot assay. In EV patients, Beta types were found in all lesions (5\/5), including the potentially high-risk HPV types 5 and 8, mostly in multiple infections. In non-EV patients, cutaneous types were found in 50.0% of BL, 43.4% of AK, 31.1% of SCC, and 16.7% of BCC. Beta HPVs were the most frequently found in all lesions, being present in all AK and SCC cases that were positive for HPV. No type-specific correlation with lesion severity was found. In our series, a wide spectrum of cutaneous HPV types was detected in different skin lesions. A possible role for these HPVs in skin carcinogenesis deserves further study.","palabras_clave":"CUTANEOUS HUMAN PAPILLOMAVIRUS|BASAL CELL CARCINOMA|SQUAMOUS CELL CARCINOMA|HPV GENOTYPING|SKIN LESIONS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8848,"idioma_id":5,"titulo":"Prácticas mortuorias de cazadores-recolectores tardíos de los desiertos de altura del Noroeste Argentino: El fardo funerario de Quebrada Seca 3","resumen":"Se presentan el análisis bioarqueológico y las características de un fardo funerario recuperado en el abrigo rocoso Quebrada Seca 3 (Antofagasta de la Sierra, Catamarca, Argentina), con fechados entre 4900 y 4400 años AP, correspondiente a cazadores recolectores en tránsito a la producción de alimentos. Los objetivos son: abordar las características bioarqueológicas del individuo, describir el fardo y su contenido y establecer el tipo de depósito funerario. El fardo es descripto y graficado mediante fotos y dibujos y se incluyen observaciones tafonómicas. Los restos humanos contenidos en el fardo se analizaron para establecer el número mínimo de individuos (NMI), medidas de abundancia taxonómica y relativa, estimación de edad y posible causa de muerte. Para definir el tipo de depósito funerario se contrastaron datos de campo y características del fardo con bibliografía especializada. El fardo funerario consiste en dos cueros de camélido, uno usado como cobertura externa y otro como envoltorio de los restos óseos humanos. Ambos cueros conforman un ?paquete? atado con dos cordeles y rodeado y cubierto por haces de gramíneas. Los restos humanos hallados dentro del fardo arrojaron un NMI de 1, menos del 65% de representación ósea y una edad estimada de 28 semanas de gestación. La posible causa de muerte de este feto habría sido su inviabilidad por parto prematuro. El depósito funerario es de tipo secundario, en el que la manipulación antrópica está referida únicamente a la desarticulación del esqueleto al ser colocado en el fardo.","palabras_clave":"BIOARQUEOLOGÍA|FETO|ENTIERRO SECUNDARIO|TRANSICION A LA PRODUCCION DE ALIMENTOS|PUNA ARGENTINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8879,"idioma_id":4,"titulo":"An Explicit Formula for the Dirac Multiplicities on Lens Spaces","resumen":"We present a new description of the spectrum of the (spin-) Dirac operator D on lens spaces. Viewing a spin lens space L as a locally symmetric space &Gamma;  Spin (2 m) \/ Spin (2 m- 1 ) and exploiting the representation theory of the Spin groups, we obtain explicit formulas for the multiplicities of the eigenvalues of D in terms of finitely many integer operations. As a consequence, we present conditions for lens spaces to be Dirac isospectral. Tackling classic questions of spectral geometry, we prove with the tools developed that neither spin structures nor isometry classes of lens spaces are spectrally determined by giving infinitely many examples of finite families of Dirac isospectral lens spaces. These results are complemented by examples found with the help of a computer.","palabras_clave":"Dirac spectrum|lens space|isospectrality"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8887,"idioma_id":4,"titulo":"Climate change and its impacts: perception and adaptation in rural areas of Manizales, Colombia","resumen":"Tropical social-ecological systems are highly vulnerable to climate change, given the limited natural climate variability in the tropics. Tropical rural populations, with livelihoods dependent on agriculture, are particularly vulnerable to climate variability and changes. To develop climate change social communication, plan and implement adaptation it is necessary to understand regional\/local climate process, risks and opportunities. It is also important to understand how local populations perceive such changes and adapt their livelihoods. Limited information is available on climate change perceptions in tropical Latin American rural populations. Hence a climate study and climate change perception survey was carried out in the Manizales Municipality, in the Andean region of Colombia and one of its major coffee growing areas. The study spanned three 'thermal' levels in the tropical Andes, 1000m a.s.l. and above, each with distinct environments and livelihoods. Climate analysis yielded significant warming trends in recent decades, particularly in temperature minima for all levels, but no significant local precipitation trends. The perception survey, carried out in sparsely populated region, mostly with limited accessibility, included 37 households, with structured and semi-structured interviews, adapted to local culture. Interviewees had little or no previous knowledge on climate change. However almost all had perceived significant changes in both temperature and precipitation, which impacted their livelihoods and environment. Some perceptions could result from a La Niña event prior to the survey, and other environmental destruction processes. Their responses to change were spontaneous adaptation, based on traditional practices and agricultural technical advice from state agencies and coffee grower associations.","palabras_clave":"CLIMATE CHANGE|COLOMBIA|PERCEPTION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8934,"idioma_id":4,"titulo":"Protective effect of Calendula Officinalis L. extract against non-enzymatic peroxidation of rat kidney microsomes and mitocondria","resumen":"Cellular metabolic changes during kidney disease may induce higher production of oxygen radicals that play a significantrole in the progression of renal damage and in the onset of important comorbidities. In the study reported here the effectof Calendula Officinalis L. extract (CO) on chemiluminescence of mitochondria and microsomes isolated from kidney ratwas analysed. After incubation of mitochondria and microsomes in an ascorbate (0.4 mM)-Fe++ (2.15 µM) system (180min at 37°C), non-enzymatic peroxidation, it was observed that the total cpm\/mg protein originated from light emission:chemiluminescence was lower in kidney mitochondria and microsomes obtained from CO group than in the control group(without CO). Moreover, it was observed that the CO was reduced, concentration dependent (0.05, 0.25, 0.35 and 0.45 mgof extract), of chemiluminescence, measured as total cpm. The analyses of chemiluminescence indicate that CO may act asantioxidant protecting rat kidney mitochondria and microsomes from peroxidative damage.","palabras_clave":"PEROXIDATION|MICROSOMES|MITOCHONDRIA|KIDNEY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8938,"idioma_id":4,"titulo":"Accelerated greenhouse gases versus slow insolation forcing induced climate changes in southern South America since the Mid&#8209;Holocene","resumen":"This paper is a pioneering analysis of past climates in southern South America combining multiproxy reconstructions and the state-of-the-art CMIP5\/PMIP3 paleoclimatic models to investigate the time evolution of regional climatic conditions from the Mid-Holocene (MH) to the present. This analysis allows a comparison between the impact of the long term climate variations associated with insolation changes and the more recent effects of anthropogenic forcing on the region. The PMIP3 multimodel experiments suggest that changes in precipitation over almost all southern South America between MH and pre-industrial (PI) times due to insolation variations are significantly larger than those between PI and the present, which are due to changes in greenhouse gas concentrations. Anthropogenic forcing has been particularly intense over western Patagonia inducing reduction of precipitation in summer, autumn and winter as a consequence of progressively weaker westerly winds over the region, which have moved further poleward, between ca. 35?55°S and have become stronger south of about 50°S. Orbital variations between the MH to the PI period increased insolation over southern South America during summer and autumn inducing warmer conditions in the PI, accentuated by the effect of anthropogenic forcing during the last century. On the other hand, changes in orbital parameters from the MH to the PI period reduced insolation during winter and spring inducing colder conditions, which have been reversed by the anthropogenic forcing.","palabras_clave":"MID-HOLOCENE |PMIP3 MODELS |FORCINGS|SOUTH AMERICA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8946,"idioma_id":4,"titulo":"Evaluation of kinetic behavior of two preparations of tylosin administered in beehives for American Foulbrood control","resumen":"We compared the kinetic behavior of tylosin (TY) administered to beehives by dusting or paper-pack placement through three treatment protocols (T1, T2, T3). T1 (Dusting): TY, divided in four portions, was sprinkled over the ends of the hives´ top bars weekly for four weeks (n=3); T2 (Paper-pack placement): TY in paper packs was administered at two-week intervals (n=3); T3 (Control): The hives were left untreated (n=3). In every inspection, from each of the nine hives, fifty young (2-day-old) larvae were sampled for drug analysis. The concentration of TY in the young larvae was determined by a microbiological assay with Geobacillus stearothermophilus ATCC 12.980 as the test organism. Results (Mean ± SD): the maximum concentration (Cmax) for T1 was 136.0 ± 194.0 for T2 144.0 ± 187.4 &#956;g\/ml; the time to reach the Cmax (tmax) for T1 was 1.5 ± 0.9, for T2 1.8 ± 1.8 h; the area under the TY-behavior-kinetics curve between 0-1392 h with T1 was 308.7 ± 185.2, with T2 326.4 ± 141.0 &#956;g\/h\/ml], indicating no statistical difference between the treatments (p>0.05). The shorter duration of paper-pack-administered TY observed in the larvae implied a lower risk of antibiotic residues in the resulting honey.","palabras_clave":"Tylosin| kinetics |beehives |American foulbrood."},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8966,"idioma_id":5,"titulo":"Trayectorias académicas de grupos generacionales y contexto político en Argentina","resumen":"Nuestro propósito es estudiar las trayectorias de los académicos argentinos distinguiendo tres grupos generacionales: noveles, intermedios y consolidados. Para ello, consideramos el perfil sociocultural de origen, el capital académico, el tiempo de acceso al cargo desde la obtención de la primera titulación, el tipo de actividades realizadas y el nivel de satisfacción de cada uno de los grupos. Nuestra hipótesis es que cada grupo generacional ha delineado su trayectoria bajo las condiciones performativas de las políticas universitarias de diferentes momentos socio-políticos. De este modo, es posible distinguir tipos de trayectorias, corroborando avances teóricos anteriores.","palabras_clave":"Profesión Académica|Política universitaria"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":8967,"idioma_id":4,"titulo":"Democratisation or credentialism? Public policies of expansion of higher education in Latin America","resumen":"In recent decades, many Latin American governments haveimplemented policies to expand opportunities in highereducation, aiming at reducing discrimination and socialinequalities. These policies have taken different forms, accordingto the peculiarities of the respective higher education systems.The purpose of this paper is to explore the scope and limitationsof these policies. We develop our analysis of theoretical literatureon the subject, and review empirical information available fromsecondary sources of recent experience in five countries:Argentina, Brazil, Chile, Mexico and Venezuela. Argentina hasincreased opportunities for disadvantaged social sectors byexpanding the public sector. Brazil has attempted to improveaccess for ethnic and social minorities in both public and privateinstitutions. Chile is a unique case because of the continuingcommitment to allow market forces to shape higher education. InMexico, increased opportunities for access have resulted from thecreation of intercultural universities and technical institutions inthe public sector, as well as through growth in the private sector.Finally, in Venezuela, expansion occurred through the creation ofa new system of universities that operates in parallel to traditionalpublic institutions. We note that, in all cases, the policies reflect anunderlying belief that there are only benefits to unlimitedexpansion, without regard to possible consequences, such as anexcess of university graduates in economies with limited jobopportunities for them. Moreover, these policies do not take intoconsideration the deficit of cultural and educational capital ofyoung people who come from the most marginalised socialsectors, deficits that may hinder their success. Concepts such as?overeducation? or ?credencialism? call into question that optimisticbelief and explain the limitations of the coverage expansion interms of real democratisation.","palabras_clave":"Inclusión|Política universitaria"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9029,"idioma_id":5,"titulo":"Los cambios legislativos como motor para la deconstrucción de la enseñanza del derecho de las familias. Reformar para transformar","resumen":"Las reformas legislativas acontecidas en los últimos años en el derecho argentino ?en especial desde la sanción de la Ley 26.618 que extiende el matrimonio a las parejas del mismo sexo y su consolidación en el nuevo Código Civil y Comercial vigente desde el 01\/08\/2015, sin poder omitir el impacto cualitativo más que cuantitativo que ha tenido la Ley 26.743 de identidad de género- constituyen un punto de inflexión en la revisión crítica de la enseñanza del derecho de familia. El pasaje del derecho de familia en singular al derecho de las familias en plural, no sólo introdujo modificaciones sustanciales en el plan de estudio de la materia, sino también ?de manera primordial y esencial- en la conceptualización y perspectiva desde donde se lo debe estudiar. ¿Qué nuevas herramientas de análisis aparecen en escena? ¿Cuáles son las problemáticas que vendrían a ampliar el campo de estudio? ¿Cuáles serían las estrategias pedagógicas hábiles para acompañar el cambio de mirada? Estos son los interrogantes que serán desentrañados en el presente artículo a los fines, en definitiva, de dimensionar el rol de la ley para transformar la realidad y a la par, para dinamizar la enseñanza del derecho.","palabras_clave":"DERECHO DE LAS FAMILIAS|CÓDIGO CIVIL Y COMERCIAL|REFORMA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9074,"idioma_id":4,"titulo":"Reconstruction of the late Holocene paleoenvironment of the western Beagle Channel (Argentina) based on a palynological analysis.","resumen":"Palynological analysis was performed on sediment samples from Arroyo Baliza site (54º 51´ S, 68º 33´ W), western sector of the Beagle Channel, Tierra del Fuego, Argentina, in order to reconstruct the palaeoenvironmental history during the Holocene marine transgressive-regressive cycle in the Beagle Channel. The palynological analysis reveals the presence of a closed-canopy Nothofagus forest development in the coastal areas under a cold, wet and variable climate conditions during the late Holocene. The marine assemblage composition shows similarities to those modern assemblages recorded in the surface samples from the Beagle Channel, characterised by the dominance of Peridiniales taxa, suggesting environmental conditions during the late Holocene comparable to today. The increasing salinity during middle Holocene was accompanied by an increase in number and diversity of the microplanktonic assemblages, suggesting the gradual installation of a marine environment as it exists today in the Beagle Channel.","palabras_clave":"MARINE PALAEOENVIRONMENTS|LATE HOLOCENE|BEAGLE CHANNEL|TIERRA DEL FUEGO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9192,"idioma_id":4,"titulo":"Quotient p-Schatten metrics on spheres","resumen":"Let S(H) be the unit sphere of a Hilbert space H and Up(H) thegroup of unitary operators in H such that u&#8722;1 belongs to the p-Schatten idealBp(H). This group acts smoothly and transitively in S(H) and endows it witha natural Finsler metric induced by the p-norm kzkp = tr(zz&#8727;)p\/21\/p. Thismetric is given bykvkx,p = min{kz &#8722; ykp : y &#8712; gx},where z &#8712; Bp(H)ah satisfies that (d&#960;x)1(z) = z · x = v and gx denotes theLie algebra of the subgroup of unitaries which fix x. We call z a lifting of v.A lifting z0 is called a minimal lifting if additionally kvkx,p = kz0kp. Inthis paper we show properties of minimal liftings and we treat the problemof finding short curves &#945; such that &#945;(0) = x and &#729;&#945;(0) = v with x &#8712; S(H)and v &#8712; TxS(H) given. Also we consider the problem of finding short curveswhich join two given endpoints x, y &#8712; S(H).","palabras_clave":"P-SCHATTEN CLASS|QUOTING METRICS|GEODESIC|HOMOGENEOUS SPASE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9299,"idioma_id":5,"titulo":"Llevar La palabra. Un análisis de la relación entre las iglesias y la escolarización de niños indígenas tobas\/qom y mbya-guaraní de Argentina","resumen":"Llevar La palabra. Un análisis de la relación entre las iglesias y la escolarización de niños indígenas tobas\/qom y mbya-guaraní de ArgentinaLa consolidación del sistema escolar argentino en el siglo XIX tuvo como principal objetivo generar un modelo homogeneizador, para población urbana o periurbana, contemplando la ?integración? al conocimiento de la lengua, historia y geografía hegemónicas. El modelo educativo sarmientino privilegió como sujeto destinatario de sus políticas a los migrantes europeos de mediados y fines del siglo XIX. La pequeña porción de la población indígena que se sumó a dicho proceso, lo hizo sin que esto supusiera un cuestionamiento del currículum hegemónico. Las poblaciones indígenas fueron contempladas como sujetos de la educación pública nacional con reglamentaciones de fines del siglo XX.En esta compleja relación entre diferentes grupos indígenas y el Estado se imbrica la acción de diversas iglesias en torno a la escolaridad de éstos pueblos, lo que merece, una atención particular. En este artículo, nos proponemos  analizar el vínculo entre las iglesias (católica y evangélicas) y diversas poblaciones indígenas, considerando los ámbitos escolares,  particularmente el proceso de alfabetización.Con su variabilidad, la mayoría de las instituciones religiosas se han manifestado como espacios con vocación formativa desde sus inicios, porque propia tarea de evangelizar implica la intención de hacer llegar a otro un conocimiento que se supone le será nuevo y que trasformará positivamente su desarrollo. En esta misma línea, muchas iglesias se han interesado por la educación escolar, en ocasiones a la vez que religiosa, de niños y niñas de diversas poblaciones.  Nuestro  propósito central será poner de relieve los roles desempeñados por los distintos agentes, objetivos y estrategias, como también las ideas sobre los otros que subyacen a estos procesos. Nos interesa sistematizar intervenciones propositivas y activas que sostuvieron el idea de transformación de los destinos de los sujetos al acercarlos al uso oral de la lengua del Estado y a su escritura. En algunos casos las intervenciones sobre los usos lingüísticos han impactado también sobre las lenguas minorizadas, como es el caso de aquellas lenguas indígenas que deben su sistema de escritura a la labor de misioneros. Las propuestas particulares presentaron diferencias que enriquecerán el análisis que aquí desarrollaremos al brindarnos matices en las formas de ejecución de los programas. Metodológicamente, este texto recuperará fuentes documentales y análisis teóricos, a la luz de exploraciones de campo etnográficas realizadas en la última década con poblaciones indígenas del norte y noroeste de Argentina (tobas\/qom y mbyá guaraní). La comparación de estos casos deviene interesante porque en ellos se dieron procesos de evangelización diferentes: por un lado, entre los tobas\/qom, luego de los contactos con la Iglesia Católica, han ganado influencia diversas iglesias evangélicas, confluyendo en la conformación de un movimiento sociorreligioso indígena que fusiona elementos ?tradicionales? qom con otros propios del evangelismo. Por otro lado, los mbya-guaraníes, habitantes de la región de mayor predominancia de expansión Jesuita, mantuvieron vínculos escolares con la iglesia católica a mediados del siglo XX, que impactaron de forma permanente hasta la actualidad.","palabras_clave":"indigenas|educacion|iglesias|estado"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9327,"idioma_id":5,"titulo":"'Yo también os digo á las armas'. Comandantes de la Guardia Nacional y caudillos mitristas en la revolución de 1874 (provincia de Buenos Aires, Argentina)","resumen":"En este artículo, estudiamos la participación que tuvieron en la revolución mitrista de 1874 los comandantes de la Guardia Nacional y los jefes militares-milicianos rebeldes de la provincia de Buenos Aires. Primero, examinamos los días iniciales de la revolución y reconstruimos el rol de las autoridades locales leales al gobierno y de los comandantes rebeldes que llevaron adelante este movimiento en la campaña. Segundo, analizamos los mecanismos de reclutamiento que implementó el coronel Benito Machado para reunir guardias nacionales y sumar recursos a la causa mitrista. Argumentamos que, si bien la victoria del gobierno representó una mayor consolidación para el Estado nacional argentino, la movilización armada que lograron los comandantes rebeldes y los caudillos mitristas evidencia su capacidad de resistencia a la pérdida del poder que aún mantenían en el sur y en la frontera de la provincia de Buenos Aires.","palabras_clave":"REVOLUCIÓN DE 1874|BUENOS AIRES|COMANDANTES DE LA GUARDIA NACIONAL|CAUDILLOS MITRISTAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9400,"idioma_id":5,"titulo":"Cultura material y sociedad en el siglo XIX: las lozas de la ciudad de Mendoza","resumen":"Considerando a la ciudad de Mendoza como sitio, se analizaron las lozas procedentes de 16 excavaciones correspondientes a contextos previos y posteriores al terremoto de 1861. Las distribuciones de lozas en el espacio por categorías o clases discriminadas según su valoración y la comparación con las tendencias de las cerámicas de producción local permiten indagar las diferencias de consumo dentro de la sociedad mendocina a lo largo del siglo XIX.","palabras_clave":"Lozas|Ciudad|Siglo XIX|Consumo"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9401,"idioma_id":5,"titulo":"Estado actual de las investigaciones de la cerámica indígena del norte de Mendoza. Tecnología, cronología y distribución","resumen":"Análisis tecno-tipológicos sobre cerámica arqueológica del norte de la provincia de Mendoza permitieron definir la variabilidad en la producción local en un lapso de casi mil años, entre aproximadamente los ca. 1200-1300 años AP. A los tipos cerámicos más conocidos y ampliamente distribuidos, Agrelo y Viluco, se sumaron otros grupos cerámicos: Gris\/Marrón, Anarajado Rojizo y Viluco Colonial. Además, los tipos locales conocidos para los tambos incaicos de Uspallata se hallaron en sitios de precordillera y piedemonte alto, y también se encontraron tiestos de cerámica foránea, como los tipos Tocota, Diaguita y Copiapó Negro sobre Rojo en los diversos ambientes del área. Las dataciones absolutas permitieron ajustar las cronologías y a partir del análisis petrográfico se detectó la correspondencia de las inclusiones con la geología local y la presencia de materias primas foráneas, lo que se interpreta como movilidad y\/o intercambio con áreas vecinas.","palabras_clave":"cerámica|Mendoza|tecnología|cronología|distribución"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9408,"idioma_id":4,"titulo":"EFFECTS OF N-3 POLYUNSATURATED FATTY ACIDS IN A MOUSE MODEL OF HSV-1 CHORIORETINITIS","resumen":"Purpose: To examine the effects of n-3 and n-6 polyunsaturated fatty acids (n-3 and n-6 PUFAs) in a murine model of herpetic chorioretinitis.METHODS:BALB\/c mice were fed on three high fat diets, which contained: Menhaden oil (rich in n-3 PUFAs); Safflower oil (rich in n-6 PUFAs); or Corn oil (rich in saturated fatty acids) as control group, 14 days previously and until 12 days following anterior chamber (AC) HSV-1 inoculation.RESULTS:Mice fed on Menhaden oil present an early development of contralateral chorioretinitis by day 6 post-AC HSV-1 inoculation and also significant increase of RNA HSV-1 expression compared with Safflower and Corn oil groups. Furthermore, mice fed on Menhaden oil showed a significant decrease secretion of TNF-&#945;, IFN-&#947;, IL-2 and IL-10 in splenic cells and both retinas.CONCLUSION:Our results showed that mice fed on Menhaden oil (n-3 PUFAs) presented an early development of contralateral chorioretinitis by day 6 post-AC HSV-1 inoculation and also a significant increase in RNA HSV-1 expression compared with animals fed on Safflower and Corn oils. This increase of HSV-1 could be associated with the higher development of chorioretinitis.","palabras_clave":"PUFA|HERPES|CHORIORETINITIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9428,"idioma_id":4,"titulo":"Retrospective analysis of bovine poisoning after plant and other compounds consumption in Argentina (2000 ? 2013)","resumen":"García JA, Cantón GJ, García B, Micheloud JF, Campero CM, Späth EJA, Odriozola E.","palabras_clave":"Toxicos|bovinos|Argentina"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9446,"idioma_id":4,"titulo":"Solving optimization problems using a Hybrid Systolic Search on GPU plus CPU","resumen":"In recent years, Graphics Processing Units (GPUs) have emerged as a powerful architecture forsolving a broad spectrum of applications in very short periods of time. However, most existing GPU optimization approaches do not exploit the full power available in a CPU-GPU platform. They have a tendency to leave one of them partially unused (usually the CPU) and fail to establish an accurate exchange of information that could help solve the target problem efficiently. Thus, better performance is expected from devising a hybrid CPU-GPU parallel algorithm that combines the highly parallel stream processing power of GPUs with the higher power of multi-core architectures. We have developed a hybrid methodology to efficiently solve optimization problems. We use a hybrid CPU-GPU architecture, to benefit from running it, in parallel, on both the CPU and the GPU. Our experiments over a heterogeneous set of combinatorial optimization problems with increasing dimensionality show a time gain of up to 365× in our proposal, while demonstrating high numerical accuracy. This work is intended to open up a new line of research that matches both architectures with new algorithms and cooperation techniques.","palabras_clave":"GPGPU|CPU-GPU Cooperative algorithm|OPTIMIZATION|Heterogeneous Architectures|Parallel Hybrid Algorithms"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9555,"idioma_id":4,"titulo":"FIRST RECORD OF VOLTZIALEAN MALE CONE (LUTANTHUS) AND PODOCARPACEAE FEMALE CONE (RISSIKISTROBUS) CONIFERS OF THE PASO FLORES FORMATION (LATE TRIASSIC) PATAGONIA, ARGENTINA. REVISION OF ITS FLORAL CONTENT","resumen":"New plant remains from the upper section of the Paso Flores Formation, at the  Cañadón de Pancho locality, western area of the Collón Curá River, Neuquén Province, Argentina are described and illustrated. These are: Lutanthus ornatus, Rissikistrobus plenus, Rissikistrobus reductus, Rissikia media, Umkomasia sp., Sphenobaiera argentinae, Pseudoctenis spatulata, Taeniopteris crassinervis, and Yabeiella brackebuschiana. In  addition, Baiera triassica Gnaedinger and Zavattieri, replacing the homonymous species  previously identified in Argentina as Baiera taeniata, Ginkgo taeniata, Sphenobaiera  taeniata, is herein described. Furthermore, species previously described for other localities in  the Paso Flores Formation are recorded for the first time for the Quemquemtreu area at  Cañadón Pancho locality. These species are: Asterotheca rigbyana, Marattiopsis muensteri, Cladophlebis kurtzii, C. indica, Dictyophyllum (Dictyophyllum) tenuifolium, Goeppertella  stipanicicii, Dicroidium incisum, D. odontopteroides, D. lancifolium, Pachydermophyllum  praecordillerae, Heidiphyllum elongatum, Baiera furcata, Sphenobaiera robusta, Pseudoctenis carteriana and P. falconeriana. The Voltziales male cone Lutanthus herein  described from the Paso Flores Formation is the second record for the Gondwana realm; the  Podocarpaceae female cone Rissikistrobus is reported for the first time from Triassic strata of  Argentina and constitutes the third record for Gondwana. Comparisons with the plant diversity recorded in other localities of the Paso Flores Formation throughout the Neuquén Province are also analyzed. The Cañadón de Pancho mega and microflora assemblages suggest a Late Triassic (Uppermost Norian = Rhaetian) age, being the youngest fossil flora recorded to date in the Triassic basins of Argentina.","palabras_clave":"MALE CONE|FEMALE CONE|UPPER TRIASSIC|ARGENTINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9600,"idioma_id":5,"titulo":"Aproximación multiproxy a los estudios paleoambientales de la provincia de Córdoba: El valle de Ongamira como caso","resumen":"El objetivo general de este trabajo es el de contribuir con nueva información arqueológica que aporte a un modelo paleoecológico general para las Sierras Pampeanas Australes desde un caso de estudio: el valle de Ongamira, donde han sido planteados cambios, discontinuidades y procesos de complejización durante el Holoceno. Se pretende asociar estos procesos a un marco paleoambiental con datos multi-proxy (dataciones absolutas por C14 y datos isotópicos asociados a estudios sedimentológicos, moluscos, microvertebrados y macro y micro-restos vegetales, entre otros).","palabras_clave":"SIERRAS PAMPEANAS AUSTRALES|PALEOAMBIENTE|MULTI PROXY|HOLOCENO MEDIO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9618,"idioma_id":4,"titulo":"'First spatio-temporal study of macroinvertebrates in the Santa Cruz River: a large glacial river about to be dammed without a comprehensive pre-impoundment study","resumen":"The Santa Cruz River is the last free-flowing river in Argentinean Patagonia. Two dams are projected, and no comprehensive pre-impoundment study has been undertaken. The present study investigated macroinvertebrate communities along three different hydrological periods and at three river sections located upstream and downstream of future dams. Fifty-three macroinvertebrate taxa were identified, with the most abundant orders being Ephemeroptera, Plecoptera, Coleoptera, and Crustacea (particularly amphipods). Ordination methods (CCA) and generalized linear models (GLM) were applied. According to the CCA, the main environmental variables related to macroinvertebrate density were temperature, suspended solids, depth, and substrate size. For the GLM, the main factors associated with macroinvertebrate abundance were location and hydrological period, and variables with the highest influences were temperature, substrate size, current speed, and depth. We anticipate that dam construction will modify in-stream habitat conditions, leading to changes in (i) macroinvertebrate community structure and (ii) local fish abundance due to loss of key prey taxa.","palabras_clave":"DAMS |LARGE RIVERS|GLMM|SOUTHERN HEMISPHERE|BENTHOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9634,"idioma_id":4,"titulo":"ABA and GA3 regulate the synthesis of primary and secondary metabolites related to alleviation from biotic and abio- tic stresses in grapevine.","resumen":"Plants are able to synthesize a large number of organic compounds. Among them, primary metabolites are known to participate in plant growth and development, whereas secondary metabolites are mostly involved in defense and other facultative processes. In grapevine, secondary metabolites, mainly polyphenols, are of great interest for the wine industry. Even though there is an extensive literature on the content and profile of those compounds in berries, scarce or no information is available regarding polyphenols in other organs. In addition, little is known about the effect of plant growth regulators (PGRs), ABA and GA3 (extensively used in table grapes) on the synthesis of primary and secondary metabolites in wine grapes. In table grapes, cultural practices include the use of GA3 sprays shortly before veraison, to increase berry and bunch size, and sugar content in fruits. Meanwhile, ABA applications to the berries on pre-veraison improve the skin coloring and sugar accumulation, anticipating the onset of veraison. Accordingly, the aim of this study is to assess and characterize primary and secondary metabolites in leaves, berries and roots of grapevine plants cv. Malbec at veraison, and their shift after ABA and GA3 aerial sprayings. Metabolic profiling was conducted using GC-MS, GC-FID and HPLC-MWD. A large set of metabolites was identified: sugars, alditols, organic acids, amino acids, polyphenols (flavonoids and non-flavonoids) and terpenes (mono-, sesqui-, di- and triterpenes). The obtained results showed that ABA applications elicited synthesis of mono- and sesquiterpenes in all assessed tissues as well as L-proline (26), acidic amino acids and anthocyanins in leaves. Additionally, applications with GA3 elicited synthesis of L-proline (26) in berries, and mono- and sesquiterpenes in all the tissues. However, treatment with GA3 seemed to block polyphenol synthesis, mainly in berries. In conclusion, ABA and GA3 applications to grapevine plants cv. Malbec influenced the synthesis of primary and secondary metabolites known to be essential for coping with biotic and abiotic stresses.","palabras_clave":"ABA GA3|POLIPHENOLS|VOCS AND TERPENES|GRAPE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9678,"idioma_id":4,"titulo":"Constructing Heterocycles by Visible Light Photocatalysis","resumen":"Abstract: Heterocycles are widely spread in natural products and in many bioactive compounds, as well as in a variety of fine chemicals. Synthesis through catalysis is always an advantageous strategy and today it is difficult to consider an approach to a target molecule without the inclusion of a catalytic step. Moreover, it is indeed almost a required characteristic for all the synthetic transformations in line with the principles of green chemistry and sustainable processes.  Chemical transformations via visible light photocatalysis are emerging strategies that meet the increasing demand for more sustainable chemical processes. Up to date, several visible light approaches have been successfully applied to various organic transformations. Moreover, potential advantages are envisaged in this highly active new field.This review gives a brief overview of methods based on visible-light photoredox catalysis that have been developed for the synthesis of heterocycles using transition metal catalysts and organic catalysts. Only works in which at least one heterocycle is constructed are included, leaving the vast area of functionalization of heterocycles for other reviews.","palabras_clave":"visible light|photocatalysis|heterocycle|electron transfer"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9697,"idioma_id":4,"titulo":"Advances in characterization and epidemiology of strawberry viruses and phytoplasmas in Argentina","resumen":"The presence of systemic pathogens, such as viruses and phytoplasmas, in strawberry plants is the usual situation worldwide. More than 20 virus species and 6 phytoplasmas 16Sr groups have been cited infecting strawberries in different countries. Petiole-insert leaflet grafting to strawberry virus indicator plants Fragaria vesca var. semperflorens (Duch.) 'Alpine', F. vesca UC5 and F. virginiana UC12, has allowed detecting the presence of virus in strawberry plants collected from commercial farms in several locations of Argentina. Strawberry mild yellow edge virus (SMYEV), Strawberry mottle virus (SMoV), Strawberry crinkle virus (SCV) and Strawberry polerovirus 1 (SPV1) have been identified and characterized using reverse transcription polymerase chain reaction (RT-PCR) with specific primers and sequencing parts, or complete genome of the viruses. These viruses have been detected in different producing regions, in simple or mixed infections. In parallel, numerous species of aphids (virus vectors), such as Aphis forbesi Weed, A. gossypii Glover, Chaetosiphon fragaefolii (Cockerell), C. minor (Forbes), C. thomasi Hille Ris Lambers, Macrosiphum euphorbiae (Thomas) and Myzus persicae (Sulzer), have also been found. Two different phytoplasmas have been detected in strawberry in Argentina up to now. Argentinean Strawberry Phyllody (ASP) and Strawberry red leaf (StrawRL) phytoplasmas. The Instituto Nacional de Tecnologia Agropecuaria (INTA) from Argentina have implemented a pathogen-free plants production program, where plants are obtained by meristem culture in vitro, and then they are transferred to ex vitro conditions to the screenhouses under controlled environmental conditions. All the plants obtained are tested for virus and phytoplasm by grafting to indicator plants, RT-PCR with specific primer for viruses and PCR for phytoplasmas. The plants with negative results to the tests performed are propagated in a greater scale in isolated area (nurseries). This methodology allows not only increasing fruit yield but also contributes to prevent pathogen dispersion.","palabras_clave":"STRAWBERRY|VIRUS|EPIDEMIOLOGY|CHARACTERIZATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9704,"idioma_id":4,"titulo":"Analysis of the Illapel Mw = 8.3 Thrust Earthquake Rupture Zone Using GOCE-Derived Gradients","resumen":"Satellite gravimetry has proven to be a useful tool to identify mass anomalies along a subduction interface, interpreted as heterogeneities related to the rupture process during megathrust earthquakes. In the last years, different works, reinforced with data derived from satellite gravity missions as GRACE and now GOCE, have analyzed not only the static component of the Earth gravity field, but also its temporal variations and relation to the seismic cycle.In particular, during the last decade, the Chilean margin has been affected by three megathrust earthquakes (with Mw >8): Maule 2010 Mw = 8.8, Pisagua 2014 Mw = 8.2 and recently the Mw = 8.3 Illapel event. Then, the recently completed GOCE mission (November 2009 to November 2013) offered a unique opportunity to study the Maule February 2010 and Pisagua April 2014 events by means of gravity gradients, directly measured at satellite height altitudes, which allowed mapping density heterogeneities with greater detail than the gravity anomaly which has been used in most studies up to now. In the present work, we use the last GOCE model (GO_CONS_GCF_2_DIR_R5), the one of higher spatial resolution (N = 300, k\/2 & 66 km) derived from satellite-only data. The methodology used is the same as that to study the previous events, with the addition that now we derived a relation between the associated depths of a causative mass with a determined degree of the spherical harmonic expansion. This allowed to ??decompose?? the gravimetric signal, by cutting off the degree\/order of the harmonic expansion, as depth increases. From this analysis, we found that prominent oceanic features such as the Challenger fracture zone and the Juan Fernandez ridge played a key role in latitudinal seismic segmentation for the Illapel earthquake rupture zone, acting as barriers\/attenuators to the seismic energy release. We compared the slip model from Tilmann et al. (Geophysical Research Letters 43:574?583. doi:10.1002\/2015GL066963, 2016) for the Illapel earthquake with vertical gravity gradient with and without sediment correction, and at different degree\/order of the harmonic expansion. From this analysis, we inferred that prominent oceanic features over the subducting Nazca plate play a key role in seismic segmentation not only at heavily sedimented trenches, but also at sediment-starved segments.","palabras_clave":"Vertical Gravity Gradient|Megathrust Earthquakes|South Central Andes|GOCE  Satellite"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9708,"idioma_id":4,"titulo":"Bicuculline, GABAA-receptor antagonist, blocked HPA axis activation induced by ghrelin after an acute stress","resumen":"Ghrelin is a peptide of 28 amino acids with homology between species. Ghrelin acts on the central nervous system to regulate different actions, including control of growth hormone secretion and metabolic regulation. It was suggested that central ghrelin is one such mediator of behaviors linked to stress responses and induces anxiety in rodents and birds. Previously, we observed that anxiogenic-like behavior induced by ghrelin injected into the intermediate medial mesopallium (IMM) of forebrain was blocked by bicuculline (GABAA receptor competitive antagonist) but not by diazepam (GABAA receptor allosteric agonist) in neonatal meat-type chicks (Cobb). Numerous studies indicate that hypothalamic-pituitary-adrenal (HPA) axis activation mediates the response to stress in mammals and birds. However, it is yet unclear whether this effect of ghrelin could be associated with HPA activation. Therefore, we examined whether HPA activation mediates anxiety behavior induced by Ghr injected into the IMM through GABAA receptors of neonatal chick forebrain. In Open Field test, intraperitoneal bicuculline blocked the anxiogenic-like behavior as well as the increase in plasma ACTH and corticosterone levels induced by ghrelin (30 pmol) in neonatal chicks. In the present study, we showed for the first time that a competitive antagonist of GABAA receptor suppressed the HPA axis activation induced by an anxiogenic dose of ghrelin. These results show that the anxiogenic ghrelin action involves the activation of the HPA axis, with a complex functional interaction with the GABAA receptor.","palabras_clave":"Ghrelin|GABAA receptor|corticosterone|adrenocorticotropic hormone"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9711,"idioma_id":4,"titulo":"Multiple robustness in factorized likelihood models","resumen":"In recent years, double robust procedures have led to the development of multiplerobust approaches. Dierent authors have shown consistent estimators that confer evenmore protection than double robust estimators. These estimation proposals, far frombeing constructed under a general theory, are the result of ad-hoc procedures createdfor each model considered.In this work, we develop a theoretical framework that explains the existence of multiplerobust estimators in many of the multiple robust procedures existing in factorized likelihoodmodels. This theory provides sucient conditions for the construction of multiplerobust estimating equations for the parameter of interest. We also provide sucientconditions under which it is possible to construct multiple robust estimators for certainparameters needed for the estimation of the parameter of interest.We apply this procedure to obtain a multiple robust estimator for the linear componentunder a partial lineal regression model with missing outcomes, since this model ts inthe framework of the developed theory. Also, we present the results of a Monte Carlosimulation study performed under the same model.","palabras_clave":"MULTIPLE ROBUSTNESS|FACTORIZED LIKELIHOOD MODELS |SEMIPARAMETRIC STATISTICS|MISSING DATA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9737,"idioma_id":5,"titulo":"Variabilidad de la precipitación en una región semiárida (Argentina)","resumen":"El objetivo de este estudio fue analizar la alternancia de períodos secos, húmedos y normales durante los años 1970-2012 en una región semiárida de la llanura pampeana argentina. La evolución de los rendimientos de un cultivo de secano (trigo) se analizó como indicador de dicha alternancia, durante el período 2000-2012. Se utilizó el Índice Estandarizado de Precipitación y Evapotranspiración (en inglés SPEI) y se analizó la superficie sembrada, cosechada y los rendimientos del cultivo de trigo. Los períodos normales según el SPEI fueron los más frecuentes en el área de estudio mientras que hubo una desigual proporción en la ocurrencia de eventos secos y húmedos. El año 2001 fue húmedo y  los años 2008 y 2009 fueron secos. Durante estos últimos, disminuyeron los rendimientos y la extensión de la superficie cosechada de trigo, mostrándose como indicadores  de la alternancia de períodos secos y húmedos.","palabras_clave":"VARIABILIDAD DE LA PRECIPITACIÓN|REGIÓN SEMIÁRIDA|ÍNDICE ESTANDARIZADO DE PRECIPITACIÓN Y EVAPOTRANSPIRACIÓN|PERÍODOS SECOS Y HÚMEDOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9760,"idioma_id":5,"titulo":"Modelo de distribución potencial de locaciones arqueológicas para el Periodo tardío (1200-1500 DC) en el Valle de Guandacol (oeste de la provincia de La Rioja).","resumen":"En este artículo se desarrolla un modelo de distribución potencial de locaciones arqueológicas del Período tardío (ca. 1200-1500 DC) para el valle de Guandacol (oeste de la provincia de La Rioja), a partir de relaciones entre los emplazamientos y algunas variables ambientales significativas para tales instalaciones como son -bosques nativos, precipitaciones, suelos, altimetría y ríos-. Esto es llevado a cabo a partir del manejo de un software de máxima entropía (Maxent). Esta metodología proporciona un mejor acercamiento al patrón de asentamiento, y permite evaluar qué variables del entorno físico, y en qué grado de contribución, fueron priorizadas por las poblaciones para el hábitat. Asimismo, facilita la selección de zonas para las prospecciones y aumenta la probabilidad de hallar áreas de ocupación, particularmente en territorios con condiciones geomorfológicas y antrópicas que afectan la preservación del registro cultural. Las variables que mayor aportaron en nuestro análisis son la estacionalidad de la temperatura, la proximidad a los algarrobales, en el fondo de valle, y las precipitaciones del mes más lluvioso.","palabras_clave":"MODELO DE DISTRIBUCIÓN DE LOCACIONES|VALLE DE GUANDACOL|PERIODO TARDIO|ANALISIS ESPACIAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9767,"idioma_id":4,"titulo":"Arsenic in the Health of Ecosystems: Spatial Distribution in Water, Sediment and Aquatic Biota of Pampean Streams","resumen":"Abstract A survey of arsenic and phosphorus in Pampeanstreams of Buenos Aires province was performed.Nitrates and ammonia were also determined. Streamwater was sampled as well as stream sediment andfilamentous algae. Results show that 32 streamsexceeded the arsenic recommended guidelines for humanconsumption of 10 &#956;g L&#8722;1 and six exceeded recommendedvalues for aquatic organisms? protection of50 &#956;g L&#8722;1. The average concentration found was36.54 &#956;g L&#8722;1 and areas with more concentration of Asare located in the southern region of the province, instreams that are tributaries of the Atlantic Ocean. Otherregions with high As concentration are the MatanzaRiver tributaries and the Arrecifes River tributaries. Nodifferences of As concentration was found betweenstream sediments. Also, no seasonal pattern of As concentrationwas observed in one stream sampled during ayear, but a positive correlation between As and theconductivity (p = 0.0002) and pH (p = 0.01) of thestreams was found. Also, As bioaccumulation was detectedfor all the algae sampled, but no correlationbetween As accumulated and As in the stream waterwas found. Ammonia levels exceeded recommendedguidelines for human consumption in the Argentineanlaw in 30 streams. The characterization performed inthis study provides relevant information on the distributionof arsenic and its origin and mobility.","palabras_clave":"arsenic|pollution|contamination"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9786,"idioma_id":4,"titulo":"Evaluation of the effect of soymilk fermented by a riboflavin-producing Lactobacillus plantarum strain in a murine model of colitis","resumen":"Inflammatory bowel diseases (IBD) are idiopathic diseases of the gastrointestinal tract characterised by recurrent inflammation that require lifelong treatments. It has been shown that certain strains of lactic acid bacteria (LAB) can produce specific health-promoting compounds in foods or in the gastrointestinal tract that can in turn prevent and\/or treat IBD. This study was designed to evaluate the possible therapeutic potential of soymilk fermented by the riboflavin-producing strain Lactobacillus plantarum CRL 2130 in a trinitrobenzene sulfonic induced colitis mouse model. Mice that received soymilk fermented by L. plantarum CRL 2130 showed a decrease in weight loss, lower damage scores in their large intestines, lower microbial translocation to liver and decreased cytokines levels in their intestinal fluids compared to animals that received unfermented soymilk or soymilk fermented by a nonriboflavin- producing L. plantarum strain. This is the first report that demonstrates that a riboflavin-producing LAB was able to prevent experimental colitis in a murine model.","palabras_clave":"LACTIC ACID BACTERIA|RIBOFLAVIN|COLITIS|INFLAMMATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9788,"idioma_id":4,"titulo":"Cellulosic materials as natural fillers in starch-containing matrix-based films: a review","resumen":"In this work, the different cellulosic materials, namely cellulose and lignin are analyzed. In addition, the starch-containing matrices (isolated starch and flour) reinforced with cellulosic materials to be used in packaging applications are described. Many efforts have been exerted to develop biopackaging based on renewable polymers, since these could reduce the environmental impact caused by petrochemical resources. Special attention has had the starch as macromolecule for forming biodegradable packaging. For these reasons, shall also be subject of this review the effect of each type of cellulosic material on the starch-containing matrix-based thermoplastic materials. In this manner, this review contains a description of films based on starch-containing matrices and biocomposites, and then has a review of cellulosic material-based fillers. In the same way, this review contains an analysis of the works carried out on starch-containing matrices reinforced with cellulose and lignin. Finally, the manufacturing processes of starch\/cellulose composites are provided as well as the conclusions and the outlook for future works.","palabras_clave":"Cellulosic materials|Food packaging|Starch|Biocomposites"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9811,"idioma_id":4,"titulo":"Delta 9 desaturase from Trypanosoma cruzi: key enzyme in the parasite survival. Cloning and over expression","resumen":"Desaturases, key enzymes in the metabolism of fatty acids, regulate the physical and biochemical properties of membranes. They adjust the composition of saturated and unsaturated fatty acids in response to changes in the environmental. We demonstrated the existence of &#916;9 desaturase activity in epimastigotes of the Trypanosoma cruzi Tulahuen strain. In the present study, showed that this enzyme has an approximate molecular mass of 50 kDa and a pI value of approximately 9. In order to characterize the &#916;9 desaturase of Trypanosoma cruzi, (Tc&#916;9DES) we have cloned, sequenced and expressed in Escherichia coli. The gene consists of 1300 bp and encodes a peptide of 433 amino acids with a molecular weight of 50 kDa. Analysis of the amino acid sequence revealed three clusters of histidine and two hydrophobic regions, characteristic of membrane-bound desaturases. Gene expression studies showed that Tc&#916;9DES was overexpressed as an active protein. Fatty acid analysis showed that the expressed protein was confirmed to be functional with &#916;9 desaturase activity. This enzyme changed the fatty acid profile of Tc&#916;9DES-expressing E. coli, decreasing the levels of palmitic (16:0) and stearic (18:0) acids and enhancing palmitoleic (16:1&#916;9) and monounsaturated 18 carbons fatty acids. When [1?14C]palmitic or [1?14C]stearic acid was used as substrate, Tc&#916;9DES-expressing E. coli exhibited high desaturase activity associated with increased levels of monounsaturated fatty acids, suggesting that the Tc&#916;9DES enzyme was actively expressed in E. coli. To check the commitment of Tc&#916;9DES against sterol biosynthesis inhibitors we tested the activity under ketoconazole effect. Native Tc&#916;9DES, showed a significant activity inhibition. Since Tc&#916;9DES has shown active participation under different environmental factors, among them, ketoconazole, we consider that it plays a critical role in the metabolism of the parasite","palabras_clave":"Trypanosoma cruzi, | &#916;9 desaturase,|desaturase gene,  |unsaturated fatty acids,|ketoconazole."},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9833,"idioma_id":4,"titulo":"The clustering of galaxies in the SDSS-III Baryon Oscillation Spectroscopic Survey: mock galaxy catalogues for the BOSS Final Data Release","resumen":"We present cosmological results from the final galaxy clustering data set of the Baryon Oscillation Spectroscopic Survey, part of the Sloan Digital Sky Survey III. Our combined galaxy sample comprises 1.2 million massive galaxies over an effective area of 9329 deg2 and volume of 18.7 Gpc3, divided into three partially overlapping redshift slices centred at effective redshifts 0.38, 0.51 and 0.61. We measure the angular diameter distance DM and Hubble parameterHfrom the baryon acoustic oscillation (BAO) method, in combinationwith a cosmic microwave background prior on the sound horizon scale, after applying reconstruction to reduce non-linear effects on the BAO feature. Using the anisotropic clustering of the pre-reconstruction density field, we measure the product DMH from the Alcock-Paczynski (AP) effect and the growth of structure, quantified by f&sigma;8(z), from redshift-space distortions (RSD). We combine individual measurements presented in seven companion papers into a set of consensus values and likelihoods, obtaining constraints that are tighter and more robust than those from any one method; in particular, the AP measurement from sub-BAO scales sharpens constraints from post-reconstruction BAOs by breaking degeneracy between DM and H. Combined with Planck 2016 cosmic microwave background measurements, our distance scale measurements simultaneously imply curvature &omega;K = 0.0003 &plusmn; 0.0026 and a dark energy equation-of-state parameter &omega; =-1.01 &plusmn; 0.06, in strong affirmation of the spatially flat cold dark matter (CDM) model with a cosmological constant (&Lambda;CDM). Our RSD measurements of f&sigma;8, at 6 per cent precision, are similarly consistent with this model. When combined with supernova Ia data, we find H0 = 67.3 &plusmn; 1.0 kms-1 Mpc-1 even for our most general dark energy model, in tension with some direct measurements. Adding extra relativistic species as a degree of freedom loosens the constraint only slightly, to H0 = 67.8 &plusmn; 1.2 kms-1 Mpc-1. Assuming flat &Lambda;CDM, we find &omega;m = 0.310 &plusmn; 0.005 and H0 = 67.6 &plusmn; 0.5 kms-1 Mpc-1, and we find a 95 per cent upper limit of 0.16 eV c-2 on the neutrino mass sum.","palabras_clave":"METHODS: NUMERICAL|GALAXIES: HALOES|GALAXIES: STATISTICS|LARGE-SCALE STRUCTURE OF UNIVERSE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9862,"idioma_id":4,"titulo":"EFFECTS OF LOOSE KERNEL SMUT CAUSED BY SPORISORIUM CRUENTUM ON SORGHUM HALEPENSE","resumen":"Loose Kernel smut caused by the fungus Sporisorium cruentum Kuhm (Sphacelotheca cruenta) attacks all groups of sorghum, including Johnsongrass (Sorghum halepense L.), although certain varieties in some groups are inmune or highly resistant. S. cruentum is the smut with the least incidence as disease in the genera Sorghum (Duran 1987; Fischer and Holton, 1956; Hirschhorn, 1986; Vanky, 1985). Unlike covered kernel smut, plants affected with loose kernel smut are stunted, have thin stalks, and heads emerge earlier than healthy plants. Abundant side branches (tillers) also may develop. Occasionally, the tillers are smutted, while the primary head is not. Secondary infection may occur in loose kernel smut when spores from a smutted head infect late-developing heads of healthy sorghum plants, causing them to become smutted. Sorghum halepense (=Johnsongrass) is one of the ten perenne weed species most important in the world (Holm et al, 1977). In Argentina it is spread over more than 7 millons of Ha (Mitidieri, 1984). The rhyzome constitute the most important mode of perpetuation althought seed is the principal way to dispersion and genetic variability (Ghersa et al, 1981; 1983; Mendez Fernandez et al. 1983). In Argentina, various pathogens were identified on johnsongrass, as S. cruentum, Alternaria spp., Drechslera spp., Curvularia spp., Phyllosticta spp, Phoma spp, and Bipolaris sorghicola (Hirschorn, 1986; Verdejo et al, 1995; Acciaresi and Mónaco, 1999). This complex affects the vegetative development but have scarce importance in the reproductive stage. S cruentum avoid seed development and black, small smut galls (sori) surrounded by a thin gray membrane  replaced the normal kernels. The powdery black spores (teliospores) are spread by wind and adheres to the surface of healthly kernels on neighboring plants in the same field or ones nearby before and during harvest. Also reduce vegetative and reproductive biomass (Astiz Gassó et al, 2001; Millhollon, 2000).The objetive of this work was to analyze the effect of S. cruentum on the vegetative development of rhyzomes of Johnsongrass.","palabras_clave":"SPORISORIUM|SROGHUM|SMUTS|EFFECTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9865,"idioma_id":4,"titulo":"Phylogeny of Sicariidae spiders (Araneae: Haplogynae), with a monograph on Neotropical Sicarius","resumen":"Sicariids are an infamous spider family containing two genera: the poorly known Sicarius Walckenaer and the medically important Loxosceles Heineken & Lowe. We present the first broad survey of the morphology of the family from a phylogenetic perspective in order to resolve its relationships. We scored morphological, behavioural and venom feature data for 38 taxa, including New and Old World species of both Sicarius and Loxosceles and three outgroups. Our results point to the monophyly of Sicariidae and its two genera as currently delimited, with the identification of novel synapomorphies for all of them. We present evidence of a group of ?true? Loxosceles composed of all members of the genus except those from the spinulosa species group. Sicarius have a very interesting phylogenetic structure, with species from the Americas and Africa forming reciprocally monophyletic groups. Thus, we resurrect Hexophthalma Karsch to accommodate African Sicariinae species. We discuss the evolution of venom proteins, spinning organs and cryptic appearance in Sicariidae. We delimit Sicarius to include only the 20 Neotropical species, and present a taxonomic revision of the genus. We redescribe nine previously known species, elevate one subspecies to species, and describe six new species from Argentina, Bolivia, Brazil and Peru. Sicarius levii sp. nov., from Argentina, is probably the largest known haplogyne spider in both body length and mass. Six specific names are considered junior synonyms of older names. All these species are illustrated and have their distributions mapped. We present an interactive key for identifying Sicarius species.","palabras_clave":"crypsis|evolution|morphology|new species|revision|Scytodoidea|Sphingomyelinase D|systematics|taxonomy|venom"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9927,"idioma_id":4,"titulo":"2,4-D abatement from groundwater samples by photo-Fenton processes at circumneutral pH using naturally iron present. Effect of inorganic ions","resumen":"This study evaluated, at laboratory scale, if the using iron naturally present (0.3mg L-1) and adding 10 mg L-1 of hydrogen peroxide, waseffective to remove 24.3 mgL-1 of 2,4- dichlorophenoxyacetic acid(2,4-D) from groundwater samples by simulated solar irradiation (Globalintensity= 300 W m-2). Under these conditions, the degradation of2.4-D reached 75.2% and the apparition of its main oxidation byproduct,2,4-dichlorophenol (DCP) was observed. On the other hand, pH exhibited anincreasing from 7.0 to 8.3 during the experiment. Experimentsusing Milli-Q water at pH 7.0, iron and H2O2concentrations of 0.3 mg L-1 and 10 mg L-1 respectively,were carried out in order to study the effect of ions such as carbonatespecies, phosphate and fluoride in typical concentrations often found ingroundwater. Ion concentrations were combined by using a factorial experimentaldesign 23. Results showed that carbonates and fluoride did notproduce a detrimental effect on the 2,4-D degradation; while phosphateinhibited the process. In this case, the pH increased also from 7.0 to 7.95 and8.99. Effectof parameters such as pH, iron concentration and hydrogen peroxide concentrationon the 2,4-D degradation by the photo-Fenton process in groundwater wereevaluated by using a factorial experimental design 23. Resultsshowed that the pH was the main parameter affecting the process. This studyshows for the first time that using the photo-Fenton process at circumneutralpH and iron naturally present seems to be a promising process to removepesticides from groundwater. ","palabras_clave":"advanced oxidation processes|2,4-D|fluoride|photo-Fenton|circumneutral pH|groundwater"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9931,"idioma_id":4,"titulo":"QTL mapping and analysis of the epistatic interactions for grain yield and yield-related traits in Triticum turgidum L. var. durum","resumen":"A quantitative trait loci (QTL) analysis of grain yield and yield-related traits was performed on 93 durum wheat recombinant inbred lines derived from the cross UC1113 9 Kofa. The mapping population and parental lines were analyzed considering 19 traits assessed in different Argentine environments, namely grain yield, heading date, flowering time, plantheight, biomass per plant, and spikelet number per ear, among others. A total of 224 QTL with logarithm of odds ratio (LOD) C 3 and 47 additional QTL with LOD[2.0 were detected. These QTL were clustered in 35 regions with overlapping QTL, and 12 genomicregions were associated with only one phenotypic trait. The regions with the highest number of multitrait and stable QTL were 3BS.1, 3BS.2, 2BS.1, 1BL.1, 3AL.1, 1AS, and 4AL.3. The effects of epistatic QTL and QTL 9 environment interactions were also analyzed. QTL putatively located at major gene loci (Rht, Vrn, Eps, and Ppd) as well as additionalmajor\/minor QTL involved in the complex genetic basis of yield-related traits expressed in Argentine environments were identified. Interestingly, the 3AL.1 region was found to increase yield without altering grain quality or crop phenology.","palabras_clave":"QTL|TRITICUM TURGIDUM|YIELD|YIELD COMPONENTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9954,"idioma_id":4,"titulo":"ATR-FTIR Spectrokinetic Analysis of the CO Adsorption and Oxidation at Water\/Platinum Interface","resumen":"Attenuated total reflection infrared (ATR-IR) spectroscopy is a powerful tool to investigate  reaction pathways in liquid(reactive)\/solid(catalyst) systems. Catalysts are commonly deposited  on an internal reflection elements (IRE) as layers of powders or as films (e.g. metal film), and  they are exposed to the liquid phase reactants. To obtain quantitative information of intrinsic  reaction rates, the chemical engineering aspects of an ATR flow-through cell must be evaluated.  Particularly, mass transport in the ATR cell has to be characterized. We present here an analysis  of the mass transfer from the flowing solution to the surface of the ATR crystal, where the  catalyst is deposited. Criteria to determine kinetic parameters under chemical control were  developed on the base of non-dimensional Péclet (Pe) and Sherwood (Sh) numbers, and Thiele  modulus (&#61542;cl). A Pt thin film deposited on a ZnSe IRE by vapor deposition and a layer of  Pt\/Al2O3 porous catalyst were used to study the adsorption of carbon monoxide and oxidation of  preadsorbed carbon monoxide on aqueous phase. Experimental data of the evolution of the linearly adsorbed CO (2048 cm-114 ) were fitted using a microkinetic model to obtain reaction  constants. Results reported here serve as a practical guide to quickly determine the operational limits of an ATR cell with a porous layer of catalyst deposited onto the IRE.","palabras_clave":"Microreactors|IR Spectrometry |Atenuated Total Reflexion|Mass trasnport model"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9961,"idioma_id":4,"titulo":"Alteration halos in the Tordillos sediment-hosted copper deposit of the Neuquén Basin, Argentina","resumen":"The Tordillos sediment-hosted Cu deposit is located in the north-central sector of the Huincul High structure, inthe Neuquén Basin, Argentina. It is hosted in sedimentary rocks of the Huincul Formation, an Upper Cretaceousredbed sequence deposited in a fluvial environment. Field mapping, petrography, and chemical analysis of theauthigenic clay, sulfate, carbonate, and sulfide minerals at Tordillos have identified systematic variation in alterationand paragenesis with time and with respect to the main feeder zones. The alteration associated with Cumineralization provides evidence of a multistage infiltration of fluids spatially associated with paleo-hydrocarbonmigration driven by Tertiary tectonism.Early diagenesis formed hematite, kaolinite, and calcite1 that have been preserved in the reddish brown mudstones.Later influx of hydrocarbons and warm, reduced formation waters from deeper reservoir rocks is associatedwith dissolution of early cements and clasts and precipitation of new minerals. In the thickest paleochannelsof the Huincul Formation, dissolution of early cements (hematite, kaolinite, calcite1 and barite1) andclasts locally increased the porosity of sandstones up to 24% and destroyed hematite that changed sandstonesand conglomerates from red to yellowish-grey. Bitumen impregnations are abundant along with calcite2, 3,and 4, pyrite, minor montmorillonite, quartz overgrowth, and coarse barite2 crystals with primary organicfluid inclusions at the contact with hydrocarbon tubes. The MnO enrichment of calcite in stages 3 and 4 reflectstheir precipitation under reduced conditions. Grey and greenish-grey sandstoneswithmontmorillonite, V-hematite,smectite-chlorite group minerals and pyrite, respectively are exposed between the reddish-brown mudstonesand the yellowish-grey sandstones and conglomerates. The grey and greenish-grey horizons arerepresentative of abrupt changes in Eh-pH conditions, between regional early oxidizing solutions responsiblefor the formation of early diagenetic redbeds and later infiltration of reducing fluids responsible for alterationof sedimentary rocks. Copper mineralization is located inside the altered sandstones and conglomerates zones,forming halos surrounding vertical tubes containing bitumen. These tubes are interpreted as the conduitsthrough which migrated hydrocarbons, formation waters, and subsequent chloride and metal-rich fluids. Inthese places, pyrite, calcite, and barite cements of the altered rocks, have been dissolved and replaced by copper-rich sulfides and then by late supergene Cu minerals.Interconnection among stacked permeable paleo-channels in the mid-section of the Huincul Formation facilitatedthe migration of several generations of fluids during early diagenesis, hydrocarbon up flow, and exhumation ofthe Neuquén Group, resulting in the development of alteration halos and Cu mineralization that can be used, bothin outcrop and drill core, during exploration for sediment-hosted Cu mineralization.","palabras_clave":"RED BED|HYDROCARBONS MIGRATION|REDOX REACTIONS| CU MINERALIZATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9967,"idioma_id":4,"titulo":"Normal Holonomy of CR-submanifolds","resumen":"We study the normal holonomy group, i.e. the holonomy group of thenormal connection, of a CR-submanifold of a complex space form. We show that thenormal holonomy group of a coisotropic submanifold acts as the holonomy representation of a Riemannian symmetric space. In case of a totally real submanifold we give two results about reduction of codimension. We describe explicitly the action of the normal holonomy in the case in which the totally real submanifold is contained in a totally real totally geodesic submanifold. In such a case we prove the compactness of the normal holonomy group.","palabras_clave":"NORMAL HOLONOMY|CR-SUBMANIFOLDS|NORMAL CONNECTION|S-REPRESENTATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":9997,"idioma_id":4,"titulo":"Dendritic Cells and Parasites: From Recognition and Activation to Immune Response Instruction","resumen":"The effective defense against parasite infections requires the ability to mount an appropriate andcontrolled specific immune response able to eradicate the invading pathogen while limiting thecollateral damage to self-tissues. Dendritic cells are key elements for the development of immunityagainst parasites; they control the responses required to eliminate these pathogens while maintaininghost homeostasis. Ligation of dendritic cells Pattern Recognition Receptors by Pathogen AssociatedMolecular Pattern present in the parasites initiates signaling pathways that lead to the production ofsurface and secreted proteins that are required, together with the antigen, to induce an appropriate,and timely regulated immune response. There is evidence showing that parasites can influence andregulate dendritic cell functions in order to promote a more permissive environment for their survival.In this review, we will focus on new insights about the ability of protozoan and helminth parasites ortheir products to modify dendritic cells function and discuss how this interaction is crucial in shapingthe host response","palabras_clave":"PARASITES|TOLERANCE|INNATE IMMUNITY|DENDRITIC CELLS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10055,"idioma_id":5,"titulo":"La significancia: metáfora del sujeto","resumen":"Lacan, al afirmar que el análisis es experiencia de la palabra, apela a laLingüística con el fin de pensar el deseo en su dimensión inconsciente. Esta propuesta permite interpretar las formaciones del inconsciente según la lógica del lenguaje: los procesos de sustitución y combinación, implicando un plus de significación o significancia, a partir del anudamiento del deseo a la ley del padre, produciendo la metáfora del sujeto.","palabras_clave":"SIGNIFICANTE|SIGNIFICANCIA|METÁFORA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10056,"idioma_id":4,"titulo":"Microbial Pathogenesis.  Evaluation of the biofilm forming ability and its associated genes in Staphylococcus isolates from bovine mastitis in Argentinean dairy farms","resumen":"Staphylococcus aureus and coagulase-negative staphylococci (CNS) are important causes of intramammary infection in dairy cattle, and their ability to produce biofilm is considered an important virulence property in the pathogenesis of mastitis. However, the published date on mechanisms and factors involved in infection persistence in the mammary gland remains unclear. The aim of this study was to investigate whether the main Staphylococcus species involved in bovine intramammary infections possess specific characteristics that promote colonization of the udder. We evaluated the biofilm-forming ability and distribution of adhesion- and biofilm-associated genes of Staphylococcus spp. isolated from bovine mastitis infected animals in Argentinean dairy farms. For this purpose, the phenotypic biofilm formation ability of 209 Staphylococcus spp. from bovine mastitis was investigated. All isolates produced biofilm in vitro, being 35,0% and 45,0% of the 127 S. aureus or 51,0% and 29,0% of the 82 CNS strong and moderate biofilm producers respectively. All S. aureus samples were PCR-positive for icaA, icaD, clfA, clfB and fnbpA genes, 76.3% were positive for fnbpB gene and 11.0% were positive for bap gene. In CNS isolates, the positive rates for icaA and icaD were 73.2%, while for clfA, clfB, fnbpA fnbpB and bap genes the percentage were lower. The results demonstrate that in Staphylococcus spp. biofilm formation, the polysaccharide and the adhesion- and biofilm-associated genes are of overall importance on bovine mastitis in Argentina. Therefore, future works should focus on these pathogenic specific factors for the development of more effective therapies of control, being essential to consider the ability of isolates to produce biofilm.","palabras_clave":"mastitis|logistic biplot"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10066,"idioma_id":4,"titulo":"On the complexity of the Labelled Domination Problem in Graphs","resumen":"In 2008, Lee and Chang introduced a unified approach (labelled domination) to several domination problems ($k$-tuple domination, ${k}$-domination and $M$-domination, among others). The labelled domination problem is to find an $L$-dominating function of minimum weight in a graph. It is an NP-complete problem even when restricted to split graphs and bipartite graphs. On the other hand, it is known to be polynomial-time solvable for the class of strongly chordal graphs. In this paper we state explicit formulas that relate the domination numbers considered.These relationships allow us to enlarge the family of graphs where the labelled domination problem is polynomial-time solvable to the class of graphs having clique-width bounded by a constant.","palabras_clave":"COMPUTATIONAL COMPLEXITY|LABELLED DOMINATING FUNCTION|K-TUPLE DOMINATING FUNCTION|{K}-DOMINATING FUNCTION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10107,"idioma_id":4,"titulo":"TropicalFossil Caviomorph Rodents from the Southwestern Brazilian Amazonia in the Context of the South American Faunas:Systematics,Biochronology,and Paleobiogeography","resumen":"Abstract The fossil-bearing stratigraphic sections of the Solimões Formation(southwestern Brazilian Amazonia)are exposed mainly a long the Juruá,Purus,and Acre rivers, and in road cuts.These deposits have provided fossils of the four main lineages of Caviomorpha ? Cavioidea,Erethizontoidea,Octodontoidea,and Chinchilloidea, contributing to the under standing on the evolution of tropical Neogene rodents.Herein,our knowledge about fossil rodents from this region is reviewed.New specimens arerecorded,including taxa mentioned for this region for the first time,such as basal cavioids,Dolichotinae, Caviodon (Hydrochoeridae),and Drytomomys (Dinomyidae). Unfortunately,the deposits have no absolute ages,and based on palynological data and the biochronology of several taxa(mainly mammals),the encompassed fauna has been constrained to the late Miocene. However,some rodent lineages recorded here seem to be more related to older faunas,from the middle Miocene and Paleogene. Regarding the biogeographic and paleoenvironmental affinities, most of theNeogene rodents from the Acre regions how more similarities to those from the EntreRios, Argentina, and Urumaco, Venezuela, where we environments were present during Neogene times. An increase inprospecting along southwesternAmazonian rivers looking for rodents(among other vertebrates) associated with methods to better  constrain the ages of these faunal assemblage swill contribute to a better understanding of the evolution of the tropical rodents as well as the stratigraphy and age that portion of the basin.","palabras_clave":"CAVIOMORPHA|NEOGENE|AMAZONIA|NORTHERN SOUTH AMERICA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10133,"idioma_id":4,"titulo":"The Hindlimb myology of Tyto alba (Tytonidae, Strigiformes, Aves)","resumen":"This work is the &#64257;rst myological dissection performed in detail on the hin-dlimb of Tyto alba. Six specimens were dissected and their muscle masses wereobtained. T. alba has the classical myological pattern present in other speciesof Strigiformes, such as a well-developed m. &#64258;exor digitorum longus and theabsence of the m. plantaris, &#64258;exor cruris lateralis and ambiens. Also, T. albalacks the m. extensor propius digiti III, m. extensor propius digiti IV and m. lum-bricalis, present in the Strigidae. Hindlimb muscle mass accounts for 14.13% oftotal body mass, which is within the range of values of both nocturnal (Strigi-formes) and diurnal (Falconidae and Accipitridae) raptors. This study providesimportant information for future studies related to functional morphology andecomorphology","palabras_clave":"musculature|pelvic limb|Nocturnal raptor|Barn owl"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10135,"idioma_id":4,"titulo":"Cosmogenic 10Be denudation rates and geomorphometric analysis in the Ambato range (28°?29°S), Sierras Pampeanas, Argentina","resumen":"Quantifying denudation rates along orogenic systems is crucial to understand how tectonics and climate interact with each other to create topography. Long-term mean denudation rates estimated from geologic data in the Ambato range (Sierras Pampeanas) is 0.34 mm\/yr. When compared with short-term denudation rates from other studies northward and southward along the Argentine South Central Andes foreland, our results are similar to those found in regions with higher mean annual precipitation. Here we utilize concentrations of 10Be cosmogenic radionuclide (CRN) in river sediments from catchments along the eastern slope of the Ambato range to understand the relationship among short-term (102?104 yrs) catchment-wide denudation rates and long-term denudation rates estimated from geologic data. CRN denudation rates range between &#8764;0.038 and &#8764;0.12 mm\/yr. The relationship between geomorphometric parameters (local relief, slope, hypsometric integral, and catchment mean channel steepness index, Ksn) and CRN denudation rates shows linear behavior. The best correlation concerned Ksnindicating a strong connection in the Ambato range between tectonics and denudation. When analyzed together with denudation rates from other studies northward and southward along the South Central Andes foreland, our results are similar to those found in more arid regions and suggest that bedrock strength variations should be contemplated in a regional analysis as well as climate.","palabras_clave":"DENUDATION RATES|COSMOGENIC NUCLIDES|GEOMORPHOMETRIC PARAMETERS|NORMALIZE STEEPNESS INDEX"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10137,"idioma_id":4,"titulo":"Late Pleistocene glacial fluctuations in Cordillera Oriental, subtropical Andes","resumen":"The behavior of subtropical glaciers during Middle to Late Pleistocene global glacial maxima and abrupt climate change events, specifically in Earth´s most arid low-latitude regions, remains an outstanding problem in paleoclimatology. The present-day climate of Cordillera Oriental, in arid northwestern Argentina, is influenced by shifts in subtropical climate systems, including the South American Summer Monsoon. To understand better past glacier-subtropical climates during the global Last Glacial Maximum (LGM, 26.5&ndash;19 ka) and other time periods, we combined geomorphic features with forty-two precise 10Be ages on moraine boulders and reconstructed paleo-equilibrium line altitudes (ELA) at Nevado de Cha&ntilde;i (24&deg;S) in the arid subtropical Andes. We found a major glacial expansion at &sim;23 &plusmn; 1.6 ka, that is, during the global LGM. Additional glacial expansions are observed before the global LGM (at &sim;52&ndash;39 ka), and after, at 15 &plusmn; 0.5 and 12 &plusmn; 0.6 ka. The &sim;15 ka glacial event was found on both sides of Cha&ntilde;i and the &sim;12 ka event is only recorded on the east side. Reconstructed ELAs of the former glaciers exhibit a rise from east to west that resembles the present subtropical climate trajectory from the Atlantic side of the continent; hence, we infer that this climate pattern must have been present in the past. Based on comparison with other low-latitude paleoclimate records, such as those from lakes and caves, we infer that both temperature and precipitation influenced past glacial occurrence in this sector of the arid Andes. Our findings also imply that abrupt deglacial climate events associated with the North Atlantic, specifically curtailed meridional overturning circulation and regional cooling, may have had attendant impacts on low subtropical Southern Hemisphere latitudes, including the climate systems that affect glacial activity around Nevado de Cha&ntilde;i.","palabras_clave":"ANDES|ARGENTINA|GLACIAL GEOMORPHOLOGY|COSMOGENIC DATING"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10167,"idioma_id":4,"titulo":"Postdischarge Care of Pediatric Traumatic Brain Injury in Argentina: A Multicenter Randomized Controlled Trial.","resumen":"OBJECTIVE:To develop, in partnership with families of children with traumatic brain injury, a postdischarge intervention that is effective, simple, and sustainable.DESIGN:Randomized Controlled Trial.SETTING:Seven Level 1 Pediatric Trauma Centers in Argentina.PATIENTS:Persons less than 19 years of age admitted to one of the study hospitals with a diagnosis of severe, moderate, or complicated mild traumatic brain injury and were discharged alive.INTERVENTIONS:Patients were randomly assigned to either the intervention or standard care group. A specially trained Community Resource Coordinator was assigned to each family in the intervention group. We hypothesized that children with severe, moderate, and complicated mild traumatic brain injury who received the intervention would have significantly better functional outcomes at 6 months post discharge than those who received standard care. We further hypothesized that there would be a direct correlation between patient outcome and measures of family function.MEASUREMENTS AND MAIN RESULTS:The primary outcome measure was a composite measured at 6 months post injury. There were 308 patients included in the study (61% men). Forty-four percent sustained a complicated mild traumatic brain injury, 18% moderate, and 38% severe. Sixty-five percent of the patients were 8 years old or younger, and over 70% were transported to the hospital without ambulance assistance. There was no significant difference between groups on the primary outcome measure. There was a statistically significant correlation between the primary outcome measure and the scores on the Family Impact Module of the Pediatric Quality of Life Inventory (&#961; = 0.57; p < 0.0001). Children with better outcomes lived with families reporting better function at 6 months post injury.CONCLUSIONS:Although no significant effect of the intervention was demonstrated, this study represents the first conducted in Latin America that documents the complete course of treatment for pediatric patients with traumatic brain injury spanning hospital transport through hospital care and into the postdischarge setting.","palabras_clave":"TRAUMATIC|BRAIN|INJURY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10186,"idioma_id":5,"titulo":"Estimacion de edad a partir de radiografias periapicales:  Evaluacion y aplicacion a una coleccion osteologica documentada","resumen":"La estimación dela edad es un aspecto importante de la labor antropológica tanto en casos forenses (identificación de personas) como bioarqueológicos (reconstrucción de perfiles demográficos). De los numerosos métodos de estimación de edad, aquellos que utilizan la dentición cobran mayor relevancia en contextos donde los restos óseos se encuentran mal preservados. La mayoría de los métodos desarrollados en individuos adultos se basan en cambios morfológicos relacionados con la edad. Sin embargo existen en muchos casos limitaciones en su utilización, ya que la morfología puede verse afectada por factores externos,como también por la necesidad de preservar el elemento de la dentición. Ante esta situación Kvaal y colaboradores  74:175-185, 1995) desarrollaron un método de estimación de edad apartir de modificaciones en dimensiones del diente y cavidad pulpar realizando mediciones en radiografías periapicales. Los resultados obtenidos por los autores evidenciaron una alta correlación entre las medidas obtenidas y la edad cronológica, siendo este método además, no intrusivo ni destructivo. En el presente trabajo se aplicará esta metodología en individuos adultos pertenecientes a la colección osteológica Prof. Dr. Rómulo Lambre. La finalidad de este trabajo es analizar la factibilidad de la utilización de imágenes radiográficas de piezas dentarias uniradiculares para la estimación de edad en adultos, tomando en consideración ventajas, desventajas, problemas en su posterior interpretación de los resultados obtenidos, así como la correlación de las variables analizadas con la edad cronológica","palabras_clave":"EDAD|RADIOGRAFIAS PERIAPICALES|DIENTES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10216,"idioma_id":4,"titulo":"Insecticidal spectrum and mode of action of the Bacillus thuringiensis Vip3Ca insecticidal protein","resumen":"The Vip3Ca protein, discovered in a screening of Spanish collections of Bacillus thuringiensis, was known to be toxic to Chrysodeixis chalcites, Mamestra brassicae and Trichoplusia ni. In the present study, its activity has been tested with additional insect species and we found that Cydia pomonella is moderately susceptible to this protein. Vip3Ca (of approximately 90&nbsp;kDa) was processed to an approximately 70&nbsp;kDa protein when incubated with midgut juice in all tested species. The kinetics of proteolysis correlated with the susceptibility of the insect species to Vip3Ca. The activation was faster to slower in the following order: M. brassicae (susceptible), Spodoptera littoralis (moderately susceptible), Agrotis ipsilon and Ostrinia nubilalis (slightly susceptible). Processing Vip3Ca by O. nubilalis or M. brassicae midgut juice did not significantly changed its toxicity to either insect species, indicating that the low susceptibility of O. nubilalis is not due to a problem in the midgut processing of the toxin. M. brassicae larvae fed with Vip3Ca showed binding of this toxin to the apical membrane of the midgut epithelial cells. Histopathological inspection showed sloughing of the epithelial cells with further disruption, which suggests that the mode of action of Vip3Ca is similar to that described for Vip3Aa. Biotin-labeled Vip3Ca and Vip3Aa bound specifically to M. brassicae brush border membrane vesicles and both toxins competed for binding sites. This result suggests that insects resistant to Vip3A may also be cross-resistant to Vip3C, which has implications for Insect Resistance Management (IRM).","palabras_clave":"BACILLUS THURINGIENSIS|INSECTICIDAL TOXINS|VIP3C|INSECT PESTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10228,"idioma_id":5,"titulo":"Un balance de la negociación colectiva y su relación con la organización sindical en Argentina (2003-2015)","resumen":"El aumento de la negociación colectiva operado desde el año 2003 en Argentina dio lugar a diversos estudios centrados en el análisis de sus determinantes políticos, institucionales y económicos o bien enfocados en el estudio de su evolución y características generales. Las investigaciones se centraron en la evolución cuantitativa de las negociaciones y en su periodicidad, desplazando el estudio de los procesos de negociación y contenidos negociados. En este artículo precisamos una serie de elementos teóricos que suelen quedar relegados en los debates sobre la temática y realizamos un balance de la negociación colectiva en el período para luego reflexionar sobre el vínculo entre los procesos de negociación y la organización sindical de los trabajadores.","palabras_clave":"Negociación colectiva|organización sindical|legalidad industrial|Argentina"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10269,"idioma_id":5,"titulo":"Diferencias categóricas. La invención del intercambio social en la obra de Marcel Mauss.","resumen":"En este ensayo se intenta identificar el surgimiento y la evo­lución de uno de los objetos de investigación más importan­tes en la obra de Marcel Mauss: el intercambio. Del análisis cronológico de sus textos puede inferirse que éste aparece, en una primera instancia, como modelador social de las categorías del en­tendimiento humano de relación, primero la de causalidad, y luego la de comunidad o reciprocidad. En el marco del grupo de trabajo di­rigido por Émile Durkheim ?que constituye también el equipo editorial de la revista L?Année Sociologique?, Mauss produce en una primera etapa una obra que es producto de la división del trabajo intelectual bajo la cual se ha conformado el grupo; encontrar los diversos fundamentos sociológicos de las categorías del entendi­miento humano es uno de los objetivos principales de dicha empre­sa.","palabras_clave":"Marcel Mauss|Intercambio|Categorías del entendimiento|Don"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10364,"idioma_id":5,"titulo":"La Comisión Nacional de Energía Atómica y la consolidación del complejo empresarial en torno a la actividad nucleoeléctrica (1976-1994)","resumen":"El objetivo de este trabajo consiste en analizar las características que adquirió la consolidación de empresas mixtas en torno a la generación nucleoeléctrica por iniciativa de la Comisión Nacional de Energía Atómica (CNEA). Dicha política se hallaba en estrecha relación con la noción de desarrollo científico tecnológico autónomo y la necesidad de promover la participación de proveedores locales en el sector nucleoeléctrico a fin de fortalecer la industria nacional.Por este motivo, desde 1976 la institución venía llevando a cabo una política de entrega al sector privado y provincial de ciertas actividades ligadas a la producción de insumos para la industria nuclear. La conformación de empresas se realizó, en cada caso, bajo diversas formas jurídicas y distintos grados de partición para optimizar su gestión.","palabras_clave":"CNEA|Estado Empresario|Industria Nuclear"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10395,"idioma_id":4,"titulo":"A posteriori error estimates with point sources  in fractional Sobolev spaces","resumen":"We consider Poisson´s equation with a finite number of weighted Dirac masses as a source term, together with its discretization by means of conforming finite elements.  For the error in fractional Sobolev spaces, we propose residual-type a~posteriori estimators with a specifically tailored oscillation and show that, on two-dimensional polygonal domains, they are reliable and locally efficient.  In numerical tests, their use in an adaptive algorithm leads to optimal error decay rates.","palabras_clave":"FINITE ELEMENT METHODS|A POSTERIORI ERROR ESTIMATORS|DIRAC MASS|FRACTIONAL SOBOLEV SPACES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10413,"idioma_id":4,"titulo":"Before the freeze: otoliths from the Eocene of Seymour Island, Antarctica, reveal dominance of gadiform fishes (Teleostei)","resumen":"The first record of fossil teleostean otoliths from Antarctica is reported. The fossils were obtained from late Early Eocene shell beds of the La Meseta Formation, Seymour Island that represent the last temperate marine climate phase in Antarctica prior to the onset of cooling and subsequent glaciation during the late Eocene. A total of 17 otolith-based teleost taxa are recognized, with 10 being identifiable to species level containing nine new species and one new genus: Argentina antarctica sp. nov., Diaphus? marambionis sp. nov., Macruronus eastmani sp. nov., Coelorinchus balushkini sp. nov., Coelorinchus nordenskjoeldi sp. nov., Palimphemus seymourensis sp. nov., Hoplobrotula? antipoda sp. nov., Notoberyx cionei gen. et sp. nov. and Cepola anderssoni sp. nov. Macruronus eastmani sp. nov. is also known from the late Eocene of Southern Australia, and Tripterophycis immutatus Schwarzhans, widespread in the southern oceans during the Eocene, has been recorded from New Zealand, southern Australia, and now Antarctica. The otolith assemblage shows a typical composition of temperate fishes dominated by gadiforms, very similar at genus and family levels to associations known from middle Eocene strata of New Zealand and the late Eocene of southern Australia, but also to the temperate Northern Hemisphere associations from the Paleocene of Denmark. The Seymour Island fauna bridges a gap in the record of global temperate marine teleost faunas during the early Eocene climate maximum. The dominant gadiforms are interpreted as the main temperate faunal component, as in the Paleocene of Denmark. Here they are represented by the families Moridae, Merlucciidae (Macruroninae), Macrouridae and Gadidae. Nowadays Gadidae are a chiefly Northern Hemisphere temperate family. Moridae, Macruroninae and Macrouridae live today on the lower shelf to deep-water or mesopelagically with Macruroninae being restricted to the Southern Ocean. The extant endemic Antarctic gadiform family Muraenolepididae is missing, as are the dominant modern Antarctic fishes of the perciform suborder Notothenioidei. Recently, there has been much debate on isolated jaw bones of teleost fishes found in the La Meseta Formation and whether they would represent gadiforms (Merlucciidae in this case) or some early, primitive notothenioid. Otoliths are known to often complement rather than duplicate skeletal finds. With this in mind, we conclude that our otolith data support the presence of gadiforms in the early Eocene of Antarctica while it does not rule out the presence of notothenioids at the same time. http:\/\/zoobank.org\/urn:lsid:zoobank.org:pub:A30E5364-0003-4467-B902-43A41AD456CC","palabras_clave":"Temperate climate|Gadiformes|Antarctica|Eocene"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10419,"idioma_id":4,"titulo":"PHYLOGENETIC PLACEMENT OF A SCHISTOSOME FROM AN UNUSUAL MARINE SNAIL HOST, THE FALSE LIMPET (SIPHONARIA LESSONI) AND GULLS (LARUS DOMINICANUS) FROM ARGENTINA WITH A BRIEF REVIEW OF MARINE SCHISTOSOMES","resumen":"In the blood fluke family Schistosomatidae, marine snails are well known as intermediate hosts. Eight families of marine snails have thus far been reported to host schistosomes across the world, most of which have been implicated in human cercarial dermatitis (HCD) outbreaks. As part of our larger effort to define the species diversity and biology of schistosomes in Argentina, in particular their role in causing HCD, we searched in the marine pulmonate snail (Siphonaria lessoni) for a schistosome species described previously from S. lessoni from southern Argentina. Additionally, gulls (Larus dominicanus) collected from a different project locality (inland) were examined, because they are known to spend time in the intertidal regions. Schistosome sporocysts were found in S. lessoni, and a small worm fragment was retrieved from a gull. Molecular phylogenies for 28S, ITS1-5.8S-ITS2, and cox1 genes revealed that the specimens from the gull and S. lessoni grouped closely together, suggesting they are conspecifics. Also, ITS1-5.8S-ITS2 sequences suggested one of the schistosomes from S. lessoni and a schistosome from a South African penguin were also conspecifics. Further study is needed to verify if these specimens comprise a distinct marine clade within the larger avian schistosome clade that is comprised mostly of species using freshwater snail hosts. Thus far, it appears this group of marine schistosomes may be more likely found in the southern hemisphere. It is unclear if the observed distribution pattern of schistosomes in Siphonaria is a result of sampling bias and\/or indicative of a specific bird-snail-schistosome association. It is clear they are sharply differentiated from the basal marine clade of avian schistosomes that includes Austrobilharzia.","palabras_clave":"LARUS DOMINICANUS|SIPHONARIA LESSONI|PATAGONIA|MARINE SCHISTOSOME"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10432,"idioma_id":5,"titulo":"Calidad higiénico-sanitaria en plantas de faena de la provincia de Tucumán. Detección, aislamiento y caracterización de Escherichia coli productor de toxina Shiga","resumen":"Los bovinos son el principal reservorio de Escherichia coli  productor de toxina Shiga (STEC), y las estrategias  para evitar su transmisión se concentran en la planta de faena. El objetivo de este trabajo fue evaluar la calidad higiénico-sanitaria y la frecuencia de detección de STEC en medias reses bovinas de frigoríficos de tránsito provincial. Se procesaron 274 esponjados de media res, en 9 (3,3%) el recuento de E. coli genérico fue marginal, en 4 (1,4%) se aisló E. coli O157; 2 caracterizados como stx2c(vh-a)\/eae\/ehxA y 2 no toxigénicos , y en 1 (0,4%) muestra se aisló E. coli no-O157 ONT:H49, stx2a \/ehxA\/saa. La distribución estacional de los aislamientos fue similar, sin correlación entre recuentos marginales de E. coli genérico y aislamiento de STEC O157 y no-O157. La detección de STEC en media res, mediante técnicas sensibles, es de fundamental importancia en el monitoreo de este patógeno en plantas de faena.","palabras_clave":"STEC|TOXINA SHIGA|CONTROL HIGIENICO SANITARIO |MEDIA RES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10441,"idioma_id":4,"titulo":"Litter microbial and soil faunal communities stimulated in the wake of a volcanic eruption in a semi-arid woodland in Patagonia, Argentina","resumen":"1.Massive volcanic eruptions are one of the most prominent natural disturbances, and their effects on the structure and functioning of ecosystems can be diverse and complex. The infrequent and unpredictable nature of these events makes generalities regarding their impact on natural ecosystems difficult.2.We evaluated the effects of a massive pyroclastic eruption of the Puyehue-CordónCaulle (June 2011) on the characteristics and function of soil microbial and faunal communities in a semiarid ecosystem located 60 km from the Puyehue volcano in Patagonia, Argentina. We hypothesized that the ash deposition would negatively impact soil faunal communities and their function, due to the demonstrated insecticide effect of ash and the dilution of organic matter with ash deposition in soil. Our approach was to repeat measurements from the same site that were conducted prior to the volcanic eruption. We measured micro-environmental variables of soil moisture, pH, organic matter, microbial biomass, and soil and litter enzymatic activity. In addition, soil faunal communities of ground dwelling arthropods and nematodes were measured using a grid of pitfall traps placed in the study sites and soil composite samples respectively. We conducted a parallel experiment evaluating litter decomposition and enzymatic activity under controlled conditions with soil from the woodland site and simulated ash deposition. 3.The results showed dissimilar effects of ash deposition depending on the variable evaluated. In the field, negative effects of ash on soil water content, pH and soil organic matter were found.  Nematode abundance and microbial enzyme activity were significantly reduced in the soil, although the fact that the ash deposition occurred in a drought year could have confounded direct effects in both cases. In contrast, ground dwelling arthropods increased dramatically, and enzymatic activity in the litter layer were significantly stimulated.  Finally, litter decomposition increased four-fold with simulated ash deposition.4.Summary. Strongly contrasting with our original predictions, we observed a marked stimulation of biotic activity in the aftermath of the volcanic eruption of Puyehue volcano. Increased water retention in the ash appeared to favour enzymatic activity in the litter layer, and together with increased decomposition suggests that substrate limitation may have stimulated microbial degradation of organic matter.  Massive disturbances such as volcanic eruptions may play a key role in the long-term dynamics of biogeochemical cycles in these terrestrial ecosystems.","palabras_clave":"VOLCANIC ERUPTION|BIOGEOCHEMICAL CYCLES|GROUND DWELLING ARTHROPODS|SOIL MICROBES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10448,"idioma_id":4,"titulo":"In vitro antifungal\/fungistatic activity of manganese phosphite against soybean soil-borne pathogens","resumen":"Resumen. Las pudriciones de raíz y tallo (PRYT) en el cultivo de soja causadas por patógenos habitantes del suelo son enfermedades comúnmente encontradas en campos de soja y son una de las causas más importantes de pérdidas económicas. La sensibilidad micelial de Fusarium virguliforme, Fusarium tucumaniae, Sclerotinia sclerotiorum y Macrophomina phaseolina fue evaluada en medio de cultivo agar papa glucosa (25 mL) suplementado con diferentes concentraciones (µg mL-1) de fosfito de manganeso (PhiMn) diluido en agua (0; 25; 37.5; 50; 100; 200; 300; 400; 500; 800 y 1000). La sensibilidad del crecimiento micelial fue analizada usando análisis de regresión lineal logarítmico. La concentración de PhiMn necesaria para inhibir el 50% del crecimiento micelial (CI50) fue calculada. Los valores de CI50 fueron desde 105 µg mL-1 (Fusarium spp.) hasta 409 µg mL-1 (M. phaseolina). La formación de esclerocios fue completamente inhibida a 500 µg mL-1. Los resultados del presente estudio representan el primer reporte de la acción fungicida\/fungistática in vitro del Phi contra los hongos agentes causales de PRYT en el cultivo de soja.","palabras_clave":"FUSARIUM VIRGULIFORME|PHOSPHITE|SUDDEN DEATH|MACROPHOMINA|SCLEROTINIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10471,"idioma_id":4,"titulo":"Phylogeny of the tribe Abrotrichini (Cricetidae, Sigmodontinae): integrating morphological and molecular evidence into a new classification","resumen":"The tribe Abrotrichini (five genera and 14 living species) is a small clade within the speciose subfamily Sigmodontinae (Rodentia, Cricetidae), representing one of the extant successful radiations of mammals at southern high latitudes of the Neotropics. Its distribution is mostly Andean, reaching its greatest diversity in southern Argentina and Chile. We evaluate the phylogenetic relationships within this tribe through parsimony and Bayesian approaches based on 99 morphological characters (including 19 integumental characters, 38 skull characters, 31 dental characters, three postcranial skeletal characters, seven from the male accessory glands and phallus and one from the digestive system) and six molecular markers (one mitochondrial and five nuclear). We include representatives of all, except one, of the currently recognized species of living Abrotrichini plus one fossil form. Based on total evidence, we recovered a primary division between the genus Abrothrix and a group including the long-clawed Abrotrichini, Chelemys, Geoxus, Notiomys and Pearsonomys. Both clades are recognized and named here as subtribes. The large degree of morphological variation observed within Abrothrix suggests that species in the genus fall into four groups, which werecognize as subgenera. In addition, the two known species of Chelemys do not form a monophyletic group, and Geoxus was recovered as paraphyletic with respect to Pearsonomys. To reconcile classification and phylogenetics, we describe a new genus for Chelemys macronyx and include Pearsonomys as a junior synonym of Geoxus. Our results highlight the importance of both morphology and molecules in resolving the phylogenetic relationships within this tribe. Based on biogeographical analyses, we hypothesize that Abrotrichini originated in south-western South America by vicariance and then diversified mostly by successive dispersal events.","palabras_clave":"No consigna"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10500,"idioma_id":5,"titulo":"'Nación, mito y sociedad autoritaria. Des-hacer Brasil: una lectura sobre intervenciones de Marilena Chauí'","resumen":"El texto, requerido como contribución a un dossier en Chile sobre el pensamiento político brasilero, indaga en intervenciones de la filósofa Marilena Chauí en torno a la cuestión de la 'sociedad autoritaria' y su articulación con la invención de la nación y la estructuración de un mito de fundación del Brasil. Hace una relectura de su obra y ofrece una hipótesis de lectura de su crítica a los obstáculos a la democracia, desde su trabajo sobre Spinoza y Merleau-Ponty, pero también la sociología marxista.","palabras_clave":"CHAUÍ|SOCIEDAD AUTORITARIA|MITO|IDEOLOGÍA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10511,"idioma_id":5,"titulo":"La escenificación del cambio: intervenciones de una secretaría tutelar de un juzgado penal de menores, en la ciudad de Buenos Aires.","resumen":"A partir de mi etnografía sobre el quehacer cotidiano y las intervenciones de una secretaría tutelar de un juzgado penal de menores, en la ciudad de Buenos Ares, en este artículo me centro en lo que identifiqué como la segunda etapa del proceso de trabajo propio de esa secretaría: el tratamiento. Identifico cómo las delegadas inspectoras construyen e interpretan ciertas actitudes, actos y expresiones como una voluntad de cambio, o como una ausencia de ella, en los jóvenes, y así dan proseguimiento a su trabajo. Busco mostrar, etnográficamente, la importancia que adquiere, en esta etapa, la demostración del cambio que los jóvenes y sus familias puedan expresar, más allá de la búsqueda o expectativa de alcanzar o probar un cambio real.Mi objetivo es deconstruir ciertas imágenes cristalizadas sobre las formas de intervenir de estas profesionales, buscando, específicamente, entender los sentidos atribuidos a las nociones de resocialización y transformación de los jóvenes que pasan por la justicia de menores, enunciados como objetivos manifiestos de esa justicia. Busco evidenciar y analizar qué significan esas nociones, entendidas como categorías nativas (Geertz, 1999), en la práctica. En este sentido, busco también proponer un entendimiento de la noción de responsabilización distinto del que ha sido adjudicado en los trabajos inspirados en el planteamiento foucaultiano. Para ello, mostraré que, al menos en el contexto investigado, los procesos de responsabilidad no están necesariamente vinculados a la producción de sujetos autónomos, a la internalización universal de las normas y a las nociones de gobierno de sí (Foucault, 2007), sino a otros sentidos locales que registran modos particulares de control social y de formación de subjetividades.","palabras_clave":"SECRETARÍA TUTELAR|JUZGADO PENAL DE MENORES|JÓVENES|TRATAMIENTO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10520,"idioma_id":4,"titulo":"The combined effect of water potential and temperature on seed germination and seedling development of cacti from a mesic Argentinian ecosystem","resumen":"Global climatic change will be associated with an increase of droughts and heat waves, which can affect seed germination and plant population dynamics. Cactus species from mesic ecosystems are likely to be more affected by these events than species from arid ecosystems. The aim of the study was to assess the combined effect of water potentials and temperatures on seed germination and seedling traits in six globose cactus species from Córdoba Mountains: Echinopsis candicans, Gymnocalycium bruchii, G. capillense, G. mostii, G. quehlianum and Parodia mammulosa. A factorial experiment was performed in which four water potential levels (0, &#8722;0.2, &#8722;0.4 and &#8722;0.6 MPa) were combined with two temperature levels (25 and 32 °C). Germination (%) and mean germination time (T50) were recorded and seedling shape (width and length) was measured. In general, a decrease in water potential and an increase in temperature resulted in low germination, with different behaviors among species. At 32 °C and low water potentials, germination was low or null for almost all species. There was not a clear trend in the response of T50 to the treatments. Seedling development was highly and negatively affected by the combination of factors, particularly at low water potentials. The responses of the analyzed cactus species to low water potential were similar to those of cactus species from more arid ecosystems. Our results suggest that the studied species would be severely affected by changes in temperature and precipitation as predicted under a climate change scenario.","palabras_clave":"climate change|germination characteristics|seedling traits|Cactaceae"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10527,"idioma_id":4,"titulo":"Effects of pulsed light treatments and pectin edible coatings on the quality attributes of fresh-cut apples: a hurdle technology approach. J Sci Food Agric (2016); DOI 10.1002\/jsfa.7723. Moreira M., Alvarez MV., Martín-Belloso O. and Soliva-Fortuny R.","resumen":"AbstractBACKGROUND: Pulsed light (PL) treatments stand as an alternative for the shelf-life extension of fresh-cut products. Theantimicrobial effects of PL are well known; however, its influence on quality attributes needs to be assessed. This study wasaimed at evaluating the application of PL treatments in combination with pectin-based edible coatings enriched with dietaryfiber for the preservation of fresh-cut apples.RESULTS: Dipping of fresh-cut apples in ascorbic acid\/calcium chloride solution prior to pectin coating and PL treatments waseffective to minimize browning and softening of apple surfaces. Incorporation of fiber in the pectin coating did not cause anychange in microbial loads andsensory acceptabilityof apple cubes.Pectin-coatedPL-treated applepieces exhibited significantlyhigher antioxidant activity values than fresh and PL control samples. At the end of storage, the combination of both treatmentsresulted in an almost 2 log CFU g&#8722;1 reduction of microbial counts. Sensory attribute scores did not fall below the rejection limitthroughout 14 days, although the presence of off-odors limited the acceptability of the pectin-coated samples.CONCLUSION: The results demonstrate that PL treatments applied to pectin-coated fresh-cut apples may be used to maintainquality attributes, thus conferring prebiotic potential and extending the shelf-life of the product.© 2016 Society of Chemical IndustryKeywords:","palabras_clave":"pulsed light;|fresh-cut fruit|dietary fiber|edible coatings"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10539,"idioma_id":4,"titulo":"Discrete Time Sliding Mode Neuro Adaptive Controller for SCARA Robot Arm","resumen":"This work presents a discrete-time sliding mode neuro-adaptive control (DTSMNAC) method for robot manipulators. Due to the dynamics variations and uncertainties in the robot model, the trajectory tracking of robot manipulators has been one of the research areas for the last years. The proposed control structure is a practical design that combines a discrete-time neuro-adaptation technique with sliding mode control to compensate the dynamics variations in the robot. Using an online adaptation technique, a DTSMNAC controller is used to approximate the equivalent control in the neighborhood of the sliding surface. A sliding control is included to guarantee that the discrete-time neural sliding mode control can improve a stable closed-loop system for the trajectory tracking control of the robot with dynamics variations. The proposed technique simultaneously ensures the stability of the adaptation of the neural networks and can be obtained a suitable equivalent control when the parameters of the robot dynamics are unknown in advance. This neural adaptive system is applied to a SCARA robot manipulator and shows to be able to ensure that the output tracking error will converge to zero. Finally, experiments on a SCARA robot have been developed to show the performance of the proposed technique, including the comparison with a PID controller.","palabras_clave":"MIMO SYSTEM|NEURAL NETWOKS|NONLINEAR CONTROL|ADAPTIVE CONTROL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10552,"idioma_id":4,"titulo":"A novel association of BoLA DRB3 alleles with BLV infected cattle with different proviral loads.","resumen":"Bovine leukemia virus (BLV) is associated with the most common neoplastic disease of cattle. BLV has a silent dissemination in the herd due to infected cell exchange, thus the concentration of BLV-infected cells in blood should play a major role in the success of viral transmission. Genes from Bovine leukocyte antigen (BoLA), the MHC system of cattle, are associated with genetic resistance and susceptibility to a wide range of diseases, and also with production traits. Some BoLA DRB3.2 allele polymorphisms in Holstein cattle have been associated with resistance or susceptibility to BLV-disease development, or with proviral load (PVL). We studied 107 BLV-infected Argentinean Holstein dairy cows belonging to a unique herd. PVL was analyzed by qPCR and animals were classified as high proviral load (HPVL, N=88) and low proviral load (LPVL, N=19), and BoLA DRB3.2 alleles were genotyped. Alleles BoLA DRB3.2*1501 and *1201 were significantly associated with HPVL (p=0.0230 and p=0.0111 respectively), while allele BoLA DRB3.2*0201 was significantly associated with LPVL (p=0.0030). Our study aims to contribute to the knowledge of the association between BoLA polymorphism and development of a BLV infection profile. Genes that best explains the PVL in this population resulted BoLA DRB3.2*0201 (as a protection factor) and *1501 (as a risk factor). Allelic differences may play an important role in the development of effective immune responses. A better understanding how BoLA polymorphism contributes to these responses and the establishment of a BLV status is desirable to schedule and evaluate control measures.","palabras_clave":"DAIRY COWS|DISEASE RESISTANCE|GENETIC MARKERS|MOLECULAR BIOLOGY|CATTLE BREEDING"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10554,"idioma_id":4,"titulo":"How do Migrant Workers Respond to Labour Abuses in ?Local Sweatshops??","resumen":"This article aims to provide empirical evidence on understanding how migrant workers&rsquo; responses to labour exploitation in low-wage economies are articulated. Inspired by the low levels of conflict among workers in small urban sweatshops in Italy and Argentina, we ask ourselves what contextual and subjective factors prevent workers from organising collectively. Here we argue that in order to understand the nature of their responses, it is necessary to consider not only the organisation of the labour process, but also the class divisions within migrant communities. We also bring in briefly the role of the state in (mis)regulating migrant labour exploitation. We conclude by showing that workers&rsquo; responses are highly individualised and that community leaders with economic interests in sweatshop economies may play a role in securing their continuation by channelling the workers&rsquo; responses towards the defence of the &ldquo;ethnic economy&rdquo;.","palabras_clave":"migrant workers |ethnic economy|sweatshops|human trafficking|low-wage economy"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10567,"idioma_id":4,"titulo":"H2 separation using pressed clinoptilolite and mixed copper-clinoptilolite disk membranes","resumen":"Disk membranes machined from high-purity natural clinoptilolite rocks demonstrated promising hydrogen separation efficiency. However, these membranes cannot be adequately scaled up. To overcome this and provide process flexibility, mixed matrix membranes are required pairing small particles of natural zeolite with a binder system. A novel approach was determined to use metals as binders and was tested by comparing natural clinoptilolite compact disk membranes with and without powdered copper metal. The phase composition and morphology of the disks were characterized and gas separation performance was evaluated using single gas permeation tests. Membrane performance was improved by applying metallic copper and copper oxide filling a portion of the inter-particle spaces and creating adhesion with the zeolite particles.","palabras_clave":"Hydrogen separation|Composite membranes|Copper|Natural zeolites"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10637,"idioma_id":4,"titulo":"Energy associated tuning method for short-term series forecasting by complete and incomplete datasets","resumen":"This article presents short-term predictions using neural networks tuned by energy associated to series based-predictor filter for complete and incomplete datasets. A benchmark of high roughness time series from Mackay Glass (MG), Logistic (LOG), Henon (HEN) and some univariate series chosen from NN3 Forecasting Competition are used. An average smoothing technique is assumed to complete the data missing in the dataset. The Hurst parameter estimated through wavelets is used to estimate the roughness of the real and forecasted series. The validation and horizon of the time series is presented by the 15 values ahead. The performance of the proposed filter shows that even a short dataset is incomplete, besides a linear smoothing technique employed; the prediction is almost fair by means of SMAPE index. Although the major result shows that the predictor system based on energy associated to series has an optimal performance from several chaotic time series, in particular, this method among other provides a good estimation when the short-term series are taken from one point observations.","palabras_clave":"short time series|forecasting|missing data|Energy associated to series|complete and incomplete datasets"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10659,"idioma_id":5,"titulo":"Evaluación comparativa de la actividad triatomicida de doramectina, ivermectina y eprinomectina administradas spot-on y oral en un modelo de rata","resumen":"Introducción. La principal herramienta para el control de los triatominos, vectores de Trypanosoma cruzi, ha sido el uso masivo e intensivo de piretroides. La emergencia de resistencia a estas moléculas determina la urgente necesidad de encontrar nuevas estrategias alternativas y complementarias de control.Objetivo. Evaluar la actividad in vivo de ivermectina, doramectina y eprinomectina sobre T. infestans en un modelo de roedor (ratas Wistar).Materiales y métodos. Ninfas de quinto estadio de T. infestans fueron alimentadas a distintos tiempos sobre ratas Wistar previamente tratadas con doramectina, ivermectina, eprinomectina o dimetilsulfoxido (control) administrados tópicamente (spot-on) o por vía oral. Se determinó el efecto de cada endectocida y del dimeltilsulfóxido sobre la cantidad de sangre ingerida, volumen de excreciones emitidas y porcentaje de mortalidad. Las variables fueron analizadas por ANOVA, con un nivel de significancia de 0.05. Resultados. No se registraron diferencias estadísticamente significativas en la cantidad de sangre ingerida y el volumen de excreciones emitidas entre vinchucas alimentadas sobre ratas tratadas con los endectocidas versus aquellas tratadas con dimetilsulfóxido. La mortalidad de los insectos dependió del endectocida administrado a las ratas y de la vía de administración utilizada. Doramectina demostró mayor efecto que ivermectina y eprinomectina, siendo la  administración tópica más efectiva.Conclusión. Los resultados obtenidos demuestran  la actividad triatomicida de los tres endectocidas. La utilización de estos ecto-endoparasiticidas  en animales peridomiciliarios o domiciliarios podría ser una interesante estrategia complementaria al rociado con piretroides para el control de T. infestans.","palabras_clave":"Triatoma infestans|endectocidas|Roedor|Anti triatoma"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10664,"idioma_id":5,"titulo":"First itraconazole resistant Aspergillus fumigatus clinical isolate harbouring a G54E substitution in Cyp51Ap in South America","resumen":"Background A 27-year-old male rural worker was admitted with a fungal keratitis due to an injury involving plant detritus. Materials and methods Specimens were collected for microscopy examination and culture. The isolate was identified by morphological and molecular criteria. Susceptibility testing was performed using CLSI methods. CYP51A gene was PCR amplified and sequenced. Results An Aspergillus fumigatus strain resistant to itraconazole (MIC > 8 &#956;g\/ml) was isolated. The isolate was susceptible to amphotericin B, posaconazole, voriconazole and caspofungin. CYP51A sequencing showed two mutations leading on the G54E substitution. The patient received natamycin as treatment. Conclusions This is the first report in South America of a clinical A. fumigatus strain carrying the substitution G54E at Cyp51Ap associated with itraconazole resistance. Considering the patient was azole-naive, this resistant isolate may have been acquired from the environment.","palabras_clave":"Aspergillus fumigatus|Azole|Resistance|CYP51"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10681,"idioma_id":4,"titulo":"THE PROTECTIVE ROLE OF VITAMIN D ON THE HEART AND THE KIDNEY","resumen":"For long time, vitamin D was regarded as an essential compound for the maintenance of appropriate calcium metabolism. Indeed, this calcium-related function were broadly studied and validated in numerous clinical and epidemiologic studies. All these vitamin D effects are mediated by a specific receptor. Remarkably, recent investigations show that the vitamin D receptor also affects autoimmunity and by these means, the course of neoplasias and tissue inflammation. Moreover, the vitamin D receptor regulates genes that affect cellular activity including cell differentiation and apoptosis and by these means angiogenesis. Actually, vitamin D deficiency has been associated to structural and functional cardiovascular changes that can be reversed by receptor stimulation. Indeed, injurious effects of vitamin D deficiency such as myocardial hypertrophy and high blood pressure seem linked to increased renin-angiotensin activity. Interestingly, chronic renal disease, a condition often associated to greater cardiovascular risk, high blood pressure, myocardial hypertrophy and inappropriate stimulation of the renin angiotensin system, is also tied to inadequate vitamin D activity. In fact, studies in several animal models as the rat ureteral obstruction model, the 5\/6 nephrectomy model and others, clearly show that vitamin D receptor stimulation prevents both structural and functional changes in the heart and the kidney.  Clinical trials are needed to validate the vitamin D potential benefits in chronic kidney disease and its associated cardiovascular risk.","palabras_clave":"KIDNEY DISEASE|HEART FAILURE|HYPERTENSION|VITAMIN D RECEPTOR"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10682,"idioma_id":4,"titulo":"MITOCHONDRIAL DYSFUNCTION LINKED TO NITRIC OXIDE PATHWAYS IN THE NEUROTOXICITY FROM GLUTAMATE","resumen":"Multiple mechanisms underlying glutamate-induced neurotoxicity have recentlybeen discussed. Likewise, a clear deregulation of the mitochondrial respiratory mechanism has been described in patients with neurodegeneration, oxidative stress, and inflammation. This article highlights nitric oxide, an atypical neurotransmitter synthesized and released on demand by the post-synaptic neurons, and has many important implications for nerve cell survival and differentiation. Consequently, synaptogenesis, synapse elimination, and neurotransmitter release, are nitric oxide-modulated. Interesting, an emergent role of nitric oxide pathways has been discussed as regards neurotoxicity from glutamate-induced apoptosis. These findings suggest that nitric oxide pathways modulation could prevent oxidative damage to neurons through apoptosis inhibition. This review aims to highlight the emergent aspects of nitricoxide-mediated signaling in the brain, and how they can be related to neurotoxicity, as well as the development of neurodegenerative diseases development.","palabras_clave":"GLUTAMATE|NITRIC OXIDE|MITOCHONDRIA|NEUROTOXICITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10734,"idioma_id":4,"titulo":". ASSESSMENT OF THE ENVIRONMENTAL QUALITY OF TWO URBANIZED LOTIC SYSTEMS USING MULTIPLE INDICATORS","resumen":"Urbanization impacts ecosystems through loss and fragmentation of habitat, loss of diversity, increase in runoff, and contaminant discharges, and the invasion of exotic species. Potrero de los Funes Village (San Luis, Argentina) is experiencing not only a population increase during summer months due to tourism but also an accelerated growth of its permanent population. In order to evaluate the potential effects of urbanization, the environmental quality of Potrero de los Funes River and Las Chacras Stream was assessed, using physical?chemical and biological indicators. Macroinvertebrates, through the application of the Biotic Index for San Luis Sierras (BISLS), anuran amphibian richness and relative abundance, and riparian vegetation were used as bioindicators. While the Simplified Index of Water Quality (SIWQ) was used to characterize the physical?chemical quality of water at each site. SIWQ and BISLS scores were significantly different between sites (F7,28 = 9.88, p <.001 and F7,28 = 24.18, p <.001, respectively). SIWQ was significantly correlated with BISLS (Spearman correlation coefficient = 0.8, p <.001). Four anuran species were registered along Potrero River, with no significant differences in the intensity of vocalizations between sites. No species were detected in Las Chacras Stream. Average total plant species richness, exotic plants richness, and vegetation cover were higher at the most impaired system, Las Chacras Stream. The principal component analysis showed that the first two principal components (PCs) explained 76.3% of the total variance. PC1, with strong loadings of SIWQ, BISLS, and amphibian richness, was principally driven by chemical water quality and biological conditions. PC2 was mainly determined by plant richness. The chemical and biological water quality of Potrero and Las Chacras is somewhat impaired, being the upper Las Chacras Stream the most compromised area. This study provides information that will certainly be used to manage future impacts of urbanization on aquatic resources.","palabras_clave":"POLLUTION|RIVER|MULTIPLE INDICATORS|WATER QUALITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10748,"idioma_id":4,"titulo":"The adhesive glands during embryogenesis of species of Phyllomedusinae (Amphibia: Anura: Hylidae)","resumen":"Among anuran embryonic structures, the adhesive (cement) glands appear posterolaterally to the stomodeum and produce amucous secretion that adheres embryos to surfaces in and out of the egg. In this paper, we study the ontogeny of the adhesive glands infive species of Phyllomedusa representing the two main clades recognized in the genus, plus embryos of Agalychnis aspera andPhasmahyla cochranae. Clutches were collected in the field, and embryos were periodically fixed to obtain complete developmental seriesand then studied with a stereomicroscope, scanning electron microscopy and routine histological techniques. Structural variationsinclude glands absent (in P. cochranae and Phyllomedusa boliviana), functional club-shaped glands (morphogenetic Type C inPhyllomedusa sauvagii, Phyllomedusa iheringii, and Phyllomedusa tetraploidea), and an unusual Type C-like pattern in Phyllomedusaazurea, characterized by large, oblong glands in a horseshoe-like disposition around the oral disc. This latter gland configuration issimilar to that of A. aspera. Interspecific variations also include the arrangement and regression pattern of the secretory region, which arein turn different from those of Type C glands in other clades. To interpret the origin and evolution of gland developmental patterns in thegroup, we still need information on gland occurrence and development in the basal genera of Phyllomedusinae (Phrynomedusa andCruziohyla) and in the basal taxa of the two major clades of Phyllomedusa.","palabras_clave":"adhesive glands|ciliation|hatching gland|external gills|oral disc"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10770,"idioma_id":4,"titulo":"Dose- and time-dependent effects of oral octopamine treatments on the sucrose responsiveness in stingless bees (Melipona scutellaris).","resumen":"Biogenic amines modulate physiological responses and, consequently, the behaviour of animals. Here,we present the first pharmacological approach to evaluate the influence of octopamine (OA) in stingless bees(Apidae, Meliponini), a group of highly eusocial bees distributed in the tropical and southern subtropical areas of theglobe. In sucrose response threshold assays, foragers of Melipona scutellaris showed an increased responsiveness tosucrose after oral OA treatments. The effect of OA on the bees? responsiveness to sucrose was OA dose-dependentand lasted for up to 1 h. Our results indicate that experimental approaches similar to the ones used for honey bees,Apis mellifera , are feasible for stingless bees. This opens opportunities to study the variability of aminergicregulation of collective behaviour in social bees.","palabras_clave":"stingless bee|gustatory responsiveness|octopamine|Melipona scutellaris"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10902,"idioma_id":5,"titulo":"Dataciones y circulación humana: influencia de las fluctuaciones del sistema lacustre Pueyrredón Posadas durante el Holoceno.","resumen":"Este trabajo se centra en la discusión del proceso de poblamiento de la cuencade los lagos Pueyrredón-Posadas-Salitroso (noroeste de Santa Cruz) sobre la base de la información obtenida en los últimos años y la presentación de nuevos fechados. Se relacionan las ocupaciones arqueológicas de la costa noreste del lago Pueyrredón con las dataciones vinculadas a la paleogeografía de la cuenca. Se analiza también la relevancia de los fechados presentados en una escala espacial más amplia, a nivel regional. Finalmente, se aborda la relación entre las variaciones de los niveles lacustres y la circulación humana teniendo en cuenta las evidencias recuperadas en los sitios emplazados en cotas superiores a los 300 mts, con cronologías correspondientes al Holoceno medio y tardío. Los resultados alcanzados confirman las expectativas planteadas por el modelo paleogeográfico; no obstante, los cambios observados en el paisaje a lo largo del Holoceno no parecen haber afectado la dinámica de la circulación humana.","palabras_clave":"Cronología|Perfiles lacustres|Circulación Humana |Patagonia"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10943,"idioma_id":4,"titulo":"Control of Paenibacillus larvae, causative agent of American foulbrood in honey bees. A review","resumen":"American foulbrood (AFB) is a severe bacterial disease that affects larvae of honey bees (Apis mellifera). The causative agent is the spore forming bacteria Paenibacillus larvae. The use of antibiotics has led to the appearance of resistant bacterial strains and residues in beehive products. Nowadays antibiotics are legally banned in several countries, and the affected colonies have to be destroyed by burning the hives. Therefore the development of alternative effective methods for the control and prevention of AFB is necessary. The traditional methods used for the control of AFB, and the natural strategies based on the application of essential oils, plant extracts, propolis, royal jelly, non conventional natural molecules, bacteria and bacteriocines, as well as the in vitro and in vivo analytical techniques used to study the antimicrobial activities against P. larvae and the toxicity on A. mellifera of those natural products are reviewed; and the results, discussed.","palabras_clave":"PAENIBACILLUS LARVAE|AMERICAN FOULBROOD|APIS MELLIFERA|NATURAL PRODUCTS|TRADITIONAL METHODS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10944,"idioma_id":4,"titulo":"Optimal concentration of organic solvents to be used in the broth microdilution method to determine the antimicrobial activity of natural products against Paenibacillus larvae","resumen":"American Foulbrood (AFB) is a bacterial disease, caused by Paenibacillus larvae, that affects honeybees (Apis mellifera). Alternative strategies to control AFB are based in the treatment of the beehives with antimicrobial natural substances such as extracts, essential oils and\/or pure compounds from plants, honey by-products, bacteria and moulds. The broth microdilution method is currently one of the most widely used methods to determine the minimum inhibitory concentration (MIC) of a substance. In this regard, the fact that most natural products, due to their lipophilic nature, must be dissolved in organic solvents or their aqueous mixtures is an issue of major concern because the organic solvent becomes part of the dilution in the incubation medium, and therefore, can interfere with bacterial viability depending on its nature and concentration. A systematic study to determine by the broth microdilution method the MIC and the maximum non inhibitory concentration (MNIC) against P. larvae of the most common organic solvents used to extract or dissolve natural products, i.e. ethanol, methanol, acetonitrile, n-butanol, dimethyl sulfoxide, and acidified hydromethanolic solutions, was carried out. From the MIC and MNIC for each organic solvent, recommended maximum concentrations in contact with P. larvae were established: 5% (v\/v) of DMSO, 7.5% (v\/v) of acetonitrile, 7.5% (v\/v) of ethanol, 12% (v\/v) of methanol, 1% (v\/v) of n-butanol, and methanol-water-acetic acid (1.25:98.71:0.04, v\/v\/v).","palabras_clave":"PAENIBACILLUS LARVAE|BROTH MICRODILUTION|ANTIMICROBIAL ACTIVITY|NATURAL PRODUCT|PLANT EXTRACT|ORGANIC SOLVENT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10951,"idioma_id":5,"titulo":"Mas alla de la clase de anatomia: redefiniendo femenino y masculino en la practica profesional de la medician mexicana","resumen":"En el marco de un estudio más amplio realizado sobre el proceso de feminización de la profesión médica en México se estudiaron las modificaciones que el proceso produce a nivel de las configuraciones de género de la mencionada profesión. Este artículo analiza parte de ese fenómeno a través de la comprensión del modo en que ciertas categorías que dan cuenta de lo femenino y lo masculino van siendo transformadas. Se plantea con ello la riqueza de un abordaje antropológico en el estudio de las relaciones de género, así como la necesidad de analizar estas desde las configuraciones profesionales, especialmente las de la profesión médica. Los sentidos en torno a términos como 'fuerza', 'sensibilidad', 'feminizarse' y 'masculinizarse' son una puerta de entrada para entender cómo, en esas disputas y actualizaciones, se encuentran cambios en torno de las ideas de masculino y femenino, y de lo que deben hacer mujeres y varones.","palabras_clave":"medicina|genero|femenino|masculino"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":10973,"idioma_id":4,"titulo":"A new marrellomorph euarthropod from the Early Ordovician of Argentina","resumen":"Marrellomorphs (class Marrellomorpha) are a group of Paleozoic arthropods with a very poor fossil record. Here we describe a new marrellomorph arthropod Mimetaster florestaensis sp. nov. from the Tremadocian (earliest Ordovician) of Argentina. The new species is characterized by the shape and direction of the three pairs of principal spines, and the existence of strong secondary spines only in the proximal two-thirds of the anterolateral spines. As a result of phylogenetic analysis the new species  integrates a trichotomy with Mimetaster hexagonalis and a Moroccan unnamed marrellid as sister groups. This discovery increases the known diversity of Marrellomorpha and represents the first occurrence of this group in South America, expanding the spatial distribution of the clade.","palabras_clave":"Marrellida|Mimetasteridae|Tremadocian|Floresta Formation|Argentina|Salta"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11053,"idioma_id":5,"titulo":"Los procesos de secularización y pos-secularización a la luz de la sociología weberiana de la racionalización","resumen":"Al calor de la perspectiva weberiana se analizan las prinmcipales discusiones sobre secularización y des-secularización contemporánea.","palabras_clave":"Weber|secularización|pos-secularización"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11140,"idioma_id":4,"titulo":"Open access and open data on natural disasters","resumen":"After a flood which devastated the city of La Plata (Argentina) in April 2013, a survey of the water situation in the region revealed that relevant studies and projects related with this area were scattered and lacked visibility. This prompted academic, scientific, technologic, and governmental institutions to take action and work together to compile, organize, and disseminate available data in an unprecedented response to an environmental disaster in the region. For this purpose, a dedicated collection was created in the SEDICI, the institutional repository for the Universidad Nacional de La Plata, and subsequently, the Observatorio Medioambiental La Plata (OMLP), a repository for data on environmental research, was launched. This document describes these collaboration initiatives which aim to anticipate and reduce the impact of natural disasters, their main characteristics, their resources, and their current progress. Projects driven by the OMLP are also described, along with a description of their technical and infrastructure deployment as per the open access policies","palabras_clave":"digital repositories |environmental observatory|floods|open access"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11143,"idioma_id":4,"titulo":"The first Black-and-chestnut Eagle (Spizaetus isidori) nest discovered in Argenentina reveals potential human-predator conflicts","resumen":"Abstract.- The Black-and-chestnut Eagle (Spizaetus isidori), is one of the least known Neotropical raptors, with scarce information about its basic ecology throughout its entire distribution range. Internationally it is categorized as Endangered. On February 17th 2014, the first nest recorded for the species in Argentina, was found in Jujuy Province. The nest is located within the UNESCO Biosphere Reserve of Las Yungas, very close to human settlements. The pair successfully bred during the austral winter and spring in 2014 and produced one fledgling. Its diet included exclusively birds, being guans (Penelope sp. possibly P. obscura and P. dabbenei) the most common prey followed by birds of prey and domestic fowl (Gallus gallus). The diet of this pair suggests that this eagle could play a relevant role as a super-predator in the study area by impacting the most relevant frugivorous species as well as other top predators. The presence of domestic fowl in the diet is especially worrisome as it suggests the existence of a real conflict between eagles and local settlers. Further work is needed to clarify whether the results from this nest are representative of other areas of the species distribution in Argentina.","palabras_clave":"águila poma|Spizaetus isidori|conflicto depredador humanos|Yungas"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11151,"idioma_id":4,"titulo":"Characterization of Nothofagus pumilio (Lenga) Understory in Managed and Unmanaged Forests of Central Patagonia, Argentina","resumen":"In managed forests, biodiversity conservation is crucial for the sustainable use of ecosystem resources. In the Patagonian-Andes forests of Argentina, lenga (Nothofagus pumilio) is the most important native tree because of its ecological functions and economic importance as a timber provider. In this study, we determined how the shelterwood-cut system impacts understory vegetation attributes in three sites representing typical lenga forests of central Andean-Patagonia. In each site, two 250-m2 treatment plots (managed and unmanaged) were established, and canopy cover, soil temperature, and moisture were determined. Within plots in 10 randomly placed 0.25-m2 microplots, we determined plant cover, from which we calculated diversity attributes. Canopy cover and soil moisture were higher in unmanaged treatments, whereas the reverse was true for soil temperature. The Shannon-Wiener index showed similar values (1), whereas species richness was slightly higher in unmanaged (4.8  0.5) than in managed treatments (3.8  0.3). Generally, native plants dominated the understory (40%), whereas exotic species were rare (1%). Shrub cover was higher in managed (24.1  4.2) than in unmanaged (9.5  1.7) treatments, whereas herbaceous species dominated unmanaged forests. These results con&#64257;rm that the shelterwood-cut system may be used for diversity conservation in Patagonian lenga forests.&nbsp;","palabras_clave":"diversity|forest harvesting|lenga|shelterwood cut system|uderstory vegetation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11160,"idioma_id":4,"titulo":"Solar UVR sensitivity of phyto- and bacterioplankton communities from  Patagonian coastal waters under increased nutrients and acidification.","resumen":"The effects of ultraviolet radiation (UVR) under future expected conditions of acidification and increase in nutrient inputs were studied on a post-bloom phytoplankton and bacterioplankton community of Patagonian coastal waters. We performed an experiment using microcosms where two environmental conditions were mimicked using a cluster approach: present (ambient nutrients and pH) and future (increased nutrients and acidification), and acclimating the samples for five days to two radiation treatments (full solar radiation [+UVR] and exclusion of UVR [?UVR]). We evaluated the short-term (hours) sensitivity of the community to solar UVR through chlorophyll a fluorescence parameters (e.g. the effective photochemical quantum yield of PSII [&#934;PSII]) at the beginning, at the mid-point and at the end of the acclimation period. Primary production and heterotrophic bacterial production (HBP) were determined, and biological weighting functions were calculated, at the beginning and at the end of the acclimation period. Mid-term effects (days) were evaluated as changes in taxonomic composition, growth rates and size structure of the community. Although the UVR-induced inhibition on &#934;PSII decreased in both clusters, samples remained sensitive to UVR after the 5 days of acclimation. Also, under the future conditions, there was, in general, an increase in the phytoplankton carbon incorporation rates along the experiment as compared to the present conditions. Bacterioplankton sensitivity to UVR changed along the experiment from inhibition to enhancement of HBP, and future environmental conditions stimulated bacterial growth, probably due to indirect effects caused by phytoplankton. Those changes in the microbial loop functioning and structure under future global change conditions might have important consequences for the carbon pump and thus for the carbon sequestration and trophodynamics of Patagonian coastal waters.","palabras_clave":"Bacterioplankton|BWF|Phytoplankton|PSII photochemistry"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11176,"idioma_id":4,"titulo":"Hypothesis of Groundwater Flow Through Geological Structures in Guarani Aquifer System (GAS) Using Chemical and Isotopic Data","resumen":"Guarani Aquifer System (GAS) is one of the most important in South America. , and iIts groundwater resources are shared byfor more than 9 million people in four countries from the South Cone (Argentina, Brazil, Paraguay and Uruguay). Groundwater flow through GAS is controlled by the geological framework of the Paraná and Chacoparanense sedimentary basins, dividing the aquifer in four groundwater flow compartments. The limit between north and central zone of the GAS and its southern compartment is represented by the Rio Grande-Asunción Arch (RGAA), a megastructure that represents a regional depositional uplift, controlling the sedimentation of the sandstones from GAS reservoir. During long time the role played by this important geological structure over the flow has remained a controversial question. Groundwater from the northern portion of the RGAA is characterized by elevated values of electrical conductivity, that can reach 2000 &#61549;S.cm-1, Na-Cl-SO4 type, and groundwater saturated with respect to calcite. On the other hand, despite their downgradient position indicated by the potentiometric surface, samples collected south of the structure, present low values of electrical conductivity, reaching 300-500 &#61549;S.cm-1. They are classified as Ca-HCO3 or Na-HCO3 types, and most samples are not saturated with respect to calcite, except those bearing high values of electrical conductivity. These differences allow inferring that groundwater flow through RGAA would not have continuity. Moreover, an important recharge zone could be stablished along the structure, responsible for the replenishment of the GAS in the southern compartment.","palabras_clave":"Guarani Aquifer System|Groundwater Flow|Geochemical evolution|Hydrochemistry"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11186,"idioma_id":5,"titulo":"Osteobiografia de dos individuos inhumados durante la Campaña del Desierto: el caso del sitio Chimpay (Argentina)","resumen":"El sitio Chimpay se encuentra en el valle medio del río Negro, pocos kilómetros al oeste de la isla de Choele Choel, en el centro-sur de la República Argentina. Se trata de un contexto de fines del siglo XIX conformado por el entierro doble de un hombre y una mujer adultos, asociados con un abundante y diverso acompañamiento funerario de origen europeo e indígena, que sugiere que habrían gozado de cierta jerarquía y que el hombre habría ostentado un cargo militar en el ejército argentino. A fin de esclarecer este complejo ritual funerario, elpresente trabajo parte de un enfoque osteobiográfico y busca avanzar en la identificación biológico-poblacional de los individuos e inferir condiciones generales de vida.","palabras_clave":"SIGLO XIX|BIOARQUEOLOGÍA|OSTEOBIOGRAFÍA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11193,"idioma_id":5,"titulo":"'El problema de la temporalidad en la fenomenología inmanente de Michel Henry'","resumen":"En L?essence de la manifestation, Michel Henry define el ego a partir de la auto-manifestación inmediata y pasiva del sentimiento de sí. En consecuencia, resulta difícil asegurarle a la subjetividad una determinación temporal. Sin embargo, nuestra hipótesis es que se puede rastrear en la obra de 1963 y en sus manuscritos preparatorios una articulación precisa y positiva entre la subjetividad y la temporalidad. Para poner a prueba esta hipótesis presentaremos primero las características generales de la subjetividad henryana y, luego, abordaremos la problemática de la temporalidad contestando a las interpretaciones tradicionales que hay del tema y proponiendo una lectura alternativa.","palabras_clave":"Michel Henry|subjetividad|auto-afección|temporalidad"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11247,"idioma_id":4,"titulo":"Physiological responses to alternative flooding and drought stress episodes in two willow (Salix spp.) clones.","resumen":"Climate change will increase the occurrence of flash floods as a consequence of extreme rain events, creating alternateperiods of drought and flooding during the growing season. We analyzed the responses of two willow clones with contrasting responses to flooding (clone B:Salix matsudana x Salix alba hybrid; clone Y: Salix alba) to different combinations ofstress treatments: continuous flooding or drought for six weeks, or cyclictreatments of two weeks of stress separated by two weeks of watering at fieldcapacity. Drought reduced growth, stomatal conductance and total leaf area inboth clones, but flooding did not. Flooding reduced the root\/shoot ratio inboth clones. The hydraulic conductivity of the main stem was significantlyreduced by drought only in clone Y. The area of the vessels was decreased byboth drought and flooding, but the number was increased only by drought. The occurrence of drought before flooding reduced thevessel area, but the opposite treatment did not. An episode of drought afterone of flooding is more stressful than the opposite situation, especially forclone Y that could not adjust its water transport capacity during the droughtperiod.&nbsp;","palabras_clave":"WATER STRESS|HYDRAULIC CONDUCTIVITY|VESSELS|STOMATAL CONDUCTANCE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11290,"idioma_id":4,"titulo":"A Political Defence of Kant's Aufklärung. An Essay","resumen":"The aim of this essay is to analyse the potential for political emancipation that lies within Kant´s conception of Aufklärung, in critical dialogue with enlightenment critics and specialized Kantian literature. My thesis is that Kant´s concept of enlightenment is intrinsically political and so it must be studied from the point of view of his political philosophy, which was fully developed in the decade of the 1790s. From this standpoint, I propose we study the role and place of Aufklärung within Kant´s central political thesis, to wit: that only the united will of the people can be a legitimate authority.","palabras_clave":"KANT|ENLIGHTENMENT|POPULAR SOVEREIGNTY|FOUCAULT |ADORNO AND HORKHEIMER"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11371,"idioma_id":4,"titulo":"Coated mesh photocatalytic reactor for air treatment applications: comparative study of support materials","resumen":"An experimental comparative study of different meshes as support materials for photocatalytic applications in gas phase is presented. The photocatalytic oxidation of dichloromethane in air was addressed employing different coated meshes in a laboratory-scale, continuous reactor. Two fiberglass meshes and a stainless steel mesh were studied regarding the catalyst load, adherence, and catalytic activity. Titanium dioxide photocatalyst was immobilized on the meshes by dip-coating cycles. Results indicate the feasibility of the dichloromethane elimination in the three cases. When the number of coating cycles was doubled, the achieved conversion levels were increased twofold for stainless steel and threefold for the fiberglass meshes. One of the fiberglass meshes (FG2) showed the highest reactivity per mass of catalyst and per catalytic surface area.","palabras_clave":"Dichloromethane|Heterogeneous photocatalysis|Indoor pollution|Mesh reactor"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11388,"idioma_id":4,"titulo":"First cosmogenic ages for glacial deposits from the Plata range (33º S): new inferences for Quaternary landscape evolution in the Central Andes","resumen":"This paper presents the first numerical cosmogenic ages of glacial deposits from the eastern slope of the Plata peak (6200 masl) in the arid Central Andes (32ºS). The moraines are distributed along three different valleys: Vallecitos, Angostura, and Las Mulas. In the first, only one moraine was identified and no blocks could be sampled for dating. The other two have evidence of two glacial advances, Angostura I and Angostura II. The advances Loma de los Morteritos I and II were recognised in the Las Mulas valley. In both cases, first and second advances are preserved at a similar altitude. Surface boulders on the top of moraines were sampled for Be10. Obtained ages are all similar and Late Pleistocene in age. They fit very well with local stratigraphy and regional paleoclimate evidence. The Loma de los Morteritos moraine II located at 3000 masl dated to ~25,000 years. Ages of ~8,000 and ~12,000 years were found for the Angostura II deposit (~3300 masl). An age was obtained for the outwash deposit identified along the El Salto valley (~69,000 years) associated with a Late Pleistocene drift. Quantitative datings presented here improve knowledge about the glacial chronology of the Plata range and Quaternary stratigraphy of the Central Andes, even though they represent a maximum age for these glacial advances. New findings support the occurrence of two Late Pleistocene glacial advances, and an older one in the Blanco River valley. Adjusted ages around ~8,000 and ~25,000 years for younger stage could be evidence of the Last Glacial Maximum (LGM) period for this region.","palabras_clave":"glaciations|TCN|Blanco river|Central Andes"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11392,"idioma_id":4,"titulo":"Files for Fiction","resumen":"In this essay, I appeal to the mental file approach in order to give an anti- realist semantic analysis of statements containing fictional names. I claim that fictive and parafictive uses of them express conceptual, though not general, propositions constituted by mental files, anchored in the conceptual world of the corresponding fictional story. Moreover, by positing a referential shift determined by the presence of a simulative referential intention characteristic of those uses, it is possible to take them to be true with respect to those conceptual worlds. As for metafictive uses, since they are grounded on mixed intentions, they are considered to express hybrid propositions, partly conceptual and partly referential.","palabras_clave":"FICTIONAL NAMES|MENTAL FILES|ANTI-REALISM|FICTIONAL CHARACTERS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11393,"idioma_id":5,"titulo":"Combinación de hongos movilizadores y solubilizadores de fósforo con rocas  fosfóricas y materiales volcánicos para la promoción del crecimiento de plantas de  lechuga (Lactuca sativa L.)","resumen":"Los hongos micorrícicos arbusculares (HMA) incrementan la toma de fosfatos solubles,mientras que los hongos solubilizadores de fósforo (S) promueven la solubilización de complejos insolubles de fosfato, en conjunto benefician la nutrición de las plantas. La utilización de estos organismos en combinación con minerales o rocas que aportannutrientes es otra alternativa para mantener la productividad de los cultivos. El objetivo de este trabajo fue combinar HMA y S con materiales piroclásticos (cenizas y pumicitas) del volcán Puyehue y rocas fosfóricas (RP) del Grupo Río Chico (Chubut) y evaluar el desempeño de estas mezclas como sustratos para la producción en maceta de Lactuca sativa. Para formular los sustratos, se utilizó como base una mezcla de Terrafertil® con cenizas. Penicillium thomii fue el S y esporas del hongo Rhizophagus intraradices (AEGIS® Irriga) sirvieron de fuente del HMA. Se evaluaron diversas combinaciones de microorganismos y la adición o no de RP. Los tratamientos fueron: 1) Sustrato; 2) Sustrato + HMA; 3) Sustrato + S; 4) Sustrato + HMA + S; 5) Sustrato: RP; 6) Sustrato: RP + HMA; 7) Sustrato: RP + S; y 8) Sustrato: RP + HMA + S. Se efectuaron 3 repeticiones por tratamiento. Los parámetros evaluados fueron el contenido de P total y asimilable en el sustrato, el P en el tejido vegetal y la biomasa seca. Todos ellos fueron significativamente mayores en las plantas que crecieron en el sustrato adicionado con RP e inoculadas con S y HMA. Este trabajo confirma que la combinación S\/HMA con cenizas volcánicas del Puyehue y las RP del Grupo Río Chico formuladas con un sustrato comercial promueven el crecimiento de L. sativa. De este modo es posible incrementar el valor agregado de geomateriales de origen nacional.","palabras_clave":"HONGOS SOLUBILIZADORAS DE P|HONGOS MOVILIZADORES DE P|ROCA FOSFORICA|CENIZAS VOLCANICAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11418,"idioma_id":4,"titulo":"Comparison between two attenuation models and precipitation evaluation with ground validation","resumen":"In this paper we present an algorithm to correctfor attenuation by absorption plus scattering, the horizontalreflectivity factor Zh of a polarimetric radar belonging to theExperimental Station of INTA, located in the town of Oro Verde,Entre Rios, Argentina. The data corresponds to storms occurredNovember 18, 2009. The correction obtained was compared withmodels from the literature. The results show good agreementfor regions with reflectivity factor lower than 55 dBZ, while forregions that go over this limit the corrections are very different.Comparisons with rain gauges indicate the need of more statisticsto improve the correlation.","palabras_clave":"ATMOSPHERIC PROPAGATION|ATTENUATION|CLOUDS|RADAR POLARIMETRY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11452,"idioma_id":4,"titulo":"Lactic acid as potential substitute of acetic acid for dissolution of chitosan: preharvest application to Butterhead lettuce","resumen":"Chitosan must be dissolved in acid solution to activate its antimicrobial properties. The objectives of present study were to determine whether acetic and lactic acids used to dissolve chitosan would influence its effectiveness to control the native microflora of Butterhead lettuce at harvest and during postharvest storage (7?8 °C, 5 days). Chitosan was applied as a SINGLE DOSE (14, 10, 7, 3 or 0 days previous to harvest) or in SUCCESSIVE DOSES (at 14 + 10 + 7+3 + 0 days prior to harvest). Although chitosan in acetic acid showed antimicrobial activity, treated plants showed dried brown stains which significantly reduced sensorial quality. Chitosan in lactic acid applied in a SINGLE DOSE at harvest or in SUCCESSIVE DOSES reduced microbial counts of all populations at harvest without affecting sensorial quality. After postharvest storage, lettuce treated with SUCCESSIVE APPLICATIONS of chitosan in lactic acid presented significant reductions in the microbial populations compared with untreated sample (&#8722;2.02 log in yeast and molds, &#8722;1.83 log in total coliforms, &#8722;1.4 log CFU g&#8722;1 in mesophilic bacteria and &#8722;1.1 log in psychrophilic bacteria). In conclusion, replacement of acetic by lactic acid did not affect the antimicrobial activity of chitosan, reducing microbial counts at harvest and after postharvest storage without affecting sensorial quality.","palabras_clave":"biopreservative|safety|greenhouse|organic"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11458,"idioma_id":4,"titulo":"FUNDAMENTAL LIMIT FOR COOLING OF LINEAR QUANTUM REFRIGERATORS","resumen":"We study the asymptotic dynamics of arbitrary linear quantum open systems which are period- ically driven while coupled with generic bosonic reservoirs. We obtain exact results for the heat current flowing into the network, which are valid beyond the usual weak coupling or Markovian approximations. We prove the validity of the dynamical third law of thermodynamics (Nernst unattainability principle) and estimate the minimum achievable temperature for any given cooling strategy. We show that the ultimate limit for cooling is imposed by a fundamental heating mecha- nism which becomes dominant at low temperatures: the non resonant creation of pairs of excitations in the reservoirs induced by the driving field. This non perturbative quantum effect restores the unattainability principle whose validity was recently challenged.","palabras_clave":"QUANTUM THERMODYNAMICS|QUANTUM REFRIGERATORS|QUANTUM SIMULATIONS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11489,"idioma_id":5,"titulo":"Diez enunciados para pensar la identidad profesional en Trabajo Social.  Una invitación al debate internacional en los albores del siglo XXI.","resumen":"El artículo de carácter teórico recupera un tópico fundamental para la disciplina desde una lectura ?situada? en la realidad sudamericana, y ?motivada? por los interrogantes que presentan los trabajadores sociales en la actualidad. A partir de un contexto de justificación que revela la necesidad de reflexionar sobre la identidad profesional, la argumentación se estructura en diez proposiciones que reúnen de manera sintética los aspectos más significativos, con el fin de recomponer una matriz analítica que exponga las restricciones más también las posibilidades de realización del núcleo duro como los márgenes con que un profesional cuenta para identificarse como tal y sustentar la conciencia profesional. Procuramos demostrar que siendo Trabajo Social emergente del proceso de modernización, y visto los cambios acontecidos en la transición al siglo XXI, habrá de revisar sus supuestos y fundamentos en clave posmoderna. En el contexto actual, el análisis respecto del rol profesional en las políticas sociales, de las prácticas, y del sujeto que da sentido a la intervención, deberá anclar en los contextos locales de práctica pero sometido al diálogo transcultural.","palabras_clave":"IDENTIDAD PROFESIONAL|MODERNIDAD|POSMODERNIDAD|PODER"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11497,"idioma_id":4,"titulo":"Use of otolith microchemistry as an indicator of the habitat of Anchoa tricolor (Spix & Agassiz, 1829) in a subtropical estuary","resumen":"The objective of the present study was to evaluate the use of sagitta otolith microchemistry (Sr:Ca; Ba:Ca ratios) as an indicator of the habitat of Anchoa tricolor between estuary and the adjacent continental shelf. We analyzed 162 specimens of A. tricolor in the Paranaguá Estuarine Complex (Brazil) and data of salinity and rainfall. The biological and environmental data were grouped into sectors (internal, intermediate and external) and periods (early and late wet and dry periods). The concentrations of Ca, Ba and Sr were determined using an ICP-OES. The Sr:Ca ratio indicated the existence of two groups of probably different origins that use the estuary at the same time but occupy different sectors of the estuary. The Ba:Ca ratio did not differ groups of use in the estuary, but rather, revealed low values suggesting that this species does not use freshwater environments. However, this ratio showed a high variation in the wet period, indicating greater availability of barium in the estuarine regions affected by river discharge. Considering our results, it is possible to classify A. tricolor as an estuarine migrant species. Also, Sr:Ca and Ba:Ca ratios can be indicative of habitat in a subtropical estuary .","palabras_clave":"otolith microchemistry |Anchoa tricolor |esturies|Brasil"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11499,"idioma_id":4,"titulo":"Otolith elemental fingerprinting and scale and otolith morphometry in Prochilodus lineatus provide identification of natal nurseries","resumen":"Identification of nursery areas is a basicrequirement for fishing management in large rivers. Morphometry(circularity, ellipticity, form factor, rectangularity and roundness indices) and chemistry (Sr:Ca, Ba:Ca and Zn:Ca ratios)of&nbsp;lapilli&nbsp;otolith, and geometric morphometry of scales ofjuveniles Prochilodus lineatus, in three sites in the Plata basin, werecompared in order to evaluate the applicability toidentify possible nursery areas. Otolithmicrochemistry based on ICP-OES found significant differences in theconcentrations of barium and zinc among sample sites. Otolith microchemistryappears to be a good effective tool in identifying individual fish fromdifferent locations (67.9%-84.2% respectively). Otolith morphometry foundsignificant differences in the ellipticity, circularity and form factor indicesbetween sites. Otolith morphological indices supported resultsfrom the elemental study with allocation success of 63.2-82.8%. Considering all scale geometricmorphometry&nbsp;variables, discriminant analysis showed a good percentage ofclassification of individuals (58.3-78.9%).&nbsp;These results indicate thatthe otolith microchemisty and morphometry (circularity and rectangularityindices) and&nbsp;scale morphometry&nbsp;are good markers of habitatand&nbsp;represent a potential tool for identification of streaked prochilod nursery areas.","palabras_clave":"streaked prochilod| otolith| scale|morphometry and microchemistry"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11503,"idioma_id":5,"titulo":"Carl Schmitt: individualismo, religión de lo privado y crisis del Estado","resumen":"El presente artículo pretende tratar la crítica de Carl Schmitt al carácter antipolítico del liberalismo desde la relación entre individualismo y religión de lo privado. Así, si la tesis weberiana sobre el particular vínculo entre protestantismo y capitalismo influye en Schmitt, lo cierto es que la adscripción de éste al catolicismo y a la perspectiva teológico-política lo lleva a extraer todas las consecuencias posibles con el fin de acentuar la impronta individualista del protestantismo precursor del liberalismo burgués. Este proceso concluye en el pathos antipolítico del liberalismo que resulta hostil al Estado desde las esferas de la moral y la economía, o bien, desde la estética como aparece en el romanticismo. Para Schmitt estos procesos concluyen en el hecho inevitable de la Entseelung que vacía de sentido a la política y consolida la era de la técnica. De este modo, la mutua implicación entre religión de lo privado, liberalismo y capitalismo tiene por resultado el ocaso definitivo del Estado.","palabras_clave":"individualismo|religión de lo privado|liberalismo"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11507,"idioma_id":5,"titulo":"El enfoque epistémico de las perspectivas biopolíticas de Foucault y Agamben. De la crítica nietzscheana del conocimiento y la genealogía, a la arqueología del poder político en Occidente","resumen":"El presente artículo busca aproximarse al enfoque epistémico de las perspectivas biopolíticas de Michel Foucault y Giorgio Agamben. Por ello, en la primera parte analizamos una de las claves para comprender el reajuste en la perspectiva foucaulteana del periodo genealógico: su recepción de la filosofía de Nietzsche. Comenzando con un análisis de la utilización que realizara el filósofo alemán de la noción de Ursprung (origen), la definición del concepto de genealogía aparece con mayor precisión desde otros conceptos como Herkunft (procedencia), Entstehung (emergencia) y Erfindung (invención). A continuación, trataremos el concepto foucaulteano de genealogía y su relación con la historia que significan un viraje importante en sus investigaciones sobre la biopolítica y que concluyen en sus análisis del biopoder. En la tercera parte, buscamos comprender algunos ejes del Proyecto Homo Sacer de Giorgio Agamben en cuanto supone una ampliación de la lectura biopolítica iniciada por Foucault. Partiendo de la influencia de algunas tesis desarrolladas por del filósofo francés y siguiendo en buena medida su estrategia metodológica, el pensador italiano elabora una perspectiva arqueológica para esclarecer los arcanos del poder soberano a través de conceptos como homo sacer, Ausnahmezustand, iustitium, nómos basileús, campo de concentración, Muselmann, gloria, aclamatio, potestas o auctoritas. Como podremos apreciar, a partir de la crítica nietzscheana del conocimiento y los alcances metodológicos de la genealogía aparece con la perspectiva biopolítica un replanteo radical de las categorías fundamentales de lo político. Lo que significa, además, una lectura crítica del modo en que es pensado el espacio de la política desde las coordenadas clásicas del zoon politikon aristotélico.","palabras_clave":"biopolítica|genealogía|arqueología"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11535,"idioma_id":5,"titulo":"VALIDACIÓN DEL GENERADOR CLIMÁTICO CLIGEN PARA PREDECIR LA EROSIÓN HÍDRICA EN EL NORTE DE LA REGIÓN PAMPEANA, ARGENTINA","resumen":"Las actividades agropecuarias están generalmente orientadas al aumento de los rendimientos de los cultivos, maximizandoel uso del recurso suelo. En este escenario, el clima juega un rol muy importante. Por esto es necesario contar con modelosque simulen adecuadamente los patrones climáticos, tanto para el crecimiento de los cultivos como para el estudio de losprocesos erosivos. El generador climático CLIGEN genera patrones de tormenta, insumo necesario para muchos modelos físicoshidrológicos como el Water Erosion Prediction Project (WEPP). Este modelo puede ser aplicado a una amplia gama de topografías,escenarios de vegetación, condiciones del suelo y climas, para estimar producción de sedimentos y escurrimiento. La validacióndel modelo CLIGEN es una condición primordial para su posterior inclusión y correcto funcionamiento del modelo WEPP. Elobjetivo de este estudio fue validar el generador climático CLIGEN para la estación meteorológica de Paraná, Entre Ríos condatos de precipitación y temperatura. Los resultados indican que la precipitación promedio anual, mensual y diaria son satisfactoriamentesimuladas por CLIGEN. Para las temperaturas máxima anual, máxima mensual y mínima mensual, no se observódiferencia significativa entre los datos medidos y los generados por el modelo. El modelo climático CLIGEN reprodujo en formasatisfactoria los parámetros promedios de todas las variables de precipitación y temperatura. Esto nos permite establecer queCLIGEN podría utilizarse con un elevado nivel de confianza para simular en forma diaria, mensual o anual distintos escenariosclimáticos futuros que alimenten modelos que estiman la pérdida de suelos como USLE, RUSLE o WEPP en nuestra región.El uso de CLIGEN en el modelo WEPP podría contribuir a generar distintos escenarios climáticos para poder predecir situacionesde riesgo de erosión hídrica","palabras_clave":"CLIMA|PRECIPITACIÓN|TEMPERATURA|EROSIÓN HÍDRICA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11546,"idioma_id":4,"titulo":"Pilot field trial of the EG95 vaccine against ovine cystic echinococcosis in Rio Negro, Argentina: Humoral response to the vaccine","resumen":"no esta disponible","palabras_clave":"hidatidosis|vacuna"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11572,"idioma_id":4,"titulo":"Late-Holocene and Little Ice Age palaeoenvironmental change inferred from pollen analysis, Isla de los Estados, Argentina","resumen":"We present pollen and spore analysis from a peat-bog section from southwestern Isla de los Estados (Staaten Island), Tierra del Fuego to better understand late-Holocene environmental change in southernmost Patagonia. The island´s position as the easternmost landmass at the southernmost of South America, places it squarely within the influence of the southern westerly winds (SWW) and the Antarctic Circumpolar Current, and so makes the island a unique location to document the palaeoecological response to climate change during the late Quaternary. We compare our Nothofagus pollen record from Bahía Franklin with other Nothofagus pollen records from Isla de los Estados and Tierra del Fuego. Nothofagus has been shown to respond to changes in mean annual temperature in the southern latitudes under cooler climate with little seasonality in precipitation. We also evaluate the correspondence between these changes in vegetation to other late-Holocene environmental proxies that include variations in sea surface temperature (SST) from the Beagle Channel and records of past glacier fluctuations. Our results show that low concentrations of Nothofagus pollen existed at Bahía Franklin at about 4000 cal yr BP. Climate ameliorated between ca. 3500 and 500 cal yr BP based on an increase in frequency and concentration values of Nothofagus and Drimys winteri. Between about 500 and 50 cal yr BP, the pollen record revealed a noticeable decline in the forest density. We interpret the decline in forest density in Isla de los Estados between 500 and &#8764;50 yr cal BP as a response to cold and windy conditions during the Little Ice Age (LIA). Our interpretation from our Nothofagus pollen record broadly agrees with regional cooling recorded in reconstructed SST of the Beagle Channel and with glacier expansion in the Fuegian Cordillera.","palabras_clave":"POLLEN|CLIMATE CHANGE|ISLA  DE LOS ESTADOS|LITTLE ICE AGE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11609,"idioma_id":4,"titulo":"Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease","resumen":"Evidence from human neuropathological studies indicates that the levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are compromised in Alzheimer´s disease. However, the causes and temporal (pathology-dependent) evolution of these alterations are not completely understood. To elucidate these issues, we investigated the McGill-R-Thy1-APP transgenic rat, which exhibits progressive intracellular and extracellular amyloid-beta (A&#946;) pathology and ensuing cognitive deficits. Neurochemical analyses revealed a differential dysregulation of NGF and BDNF transcripts and protein expression. While BDNF mRNA levels were significantly reduced at very early stages of amyloid pathology, before plaques appeared, there were no changes in NGF mRNA expression even at advanced stages. Paradoxically, the protein levels of the NGF precursor were increased. These changes in neurotrophin expression are identical to those seen during the progression of Alzheimer´s disease. At advanced pathological stages, deficits in the protease cascade controlling the maturation and degradation of NGF were evident in McGill transgenic rats, in line with the paradoxical upregulation of proNGF, as seen in Alzheimer´s disease, in the absence of changes in NGF mRNA. The compromise in NGF metabolism and BDNF levels was accompanied by downregulation of cortical cholinergic synapses; strengthening the evidence that neurotrophin dysregulation affects cholinergic synapses and synaptic plasticity. Our findings suggest a differential temporal deregulation of NGF and BDNF neurotrophins, whereby deficits in BDNF mRNA appear at early stages of intraneuronal A&#946; pathology, before alterations in NGF metabolism and cholinergic synapse loss manifest.","palabras_clave":"ALZHEIMER?S DISEASE|NGF|CHOLINERGIC FENOTYPE|SYNAPTIC PLASTICITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11626,"idioma_id":4,"titulo":"Receding horizon adaptive second-order sliding mode control for doubly-fed induction generator based wind turbines","resumen":"In this paper a novel adaptive Second-Order Sliding Mode technique to optimise the ef&#64257;ciency of certain types of variable-speed wind turbines is developed and analised. A revisited form of a recent adaptation algorithm is proposed to deal with the characteristicsand control requirements of Wind Energy Conversion Systems (WECS), particularly model uncertainties and fast disturbances due to gusty wind effects. The revisited algorithm is based on appropriate receding-horizon adaptation time windows rather than on &#64257;xed, adjacent and non overlapping ones. This modi&#64257;cation, which enhances the reactivity of the adaptation strategy against fast varying uncertainties, represents the main theoretical novelty of this work. The proposed approach is successfully used to control a Doubly-Fed Induction Generator based wind turbine topology proving its suitability for this application area. The novel adaptive controller is extensively assessed through computer simulations over a full-order realistic model of the WECS under study.","palabras_clave":"wind energy|sliding mode|adaptive control"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11629,"idioma_id":4,"titulo":"Simple TiO2 coatings by sol-gel techniques combined with commercial TiO2 particles for use in heterogeneous photocatalysis","resumen":"TiO2 coatings were obtained by a combination of a sol?gel process with the addition of commercial TiO2 particles (Degussa-Evonik P25). Simple and composite (with P25) sols were deposited by dip-coating on glass plates giving simple and composite coatings. The order of addition of reagents in the preparation of sols, the incorporation of P25 to the sols, and the thermal treatments were analyzed as variables to improve the photocatalytic activity. The samples were completely characterized with respect to the amount of deposited TiO2, the crystal structure (XRD) and the morphology (SEM). The activity of the supported photocatalysts (simple, composite and P25 coatings) was evaluated using 4-chlorophenol degradation and Cr(VI) reduction in the presence of EDTA as model photocatalytic systems. The stability of sols and the photocatalytic activity of the resulted coatings depended strongly on the order of addition of the reagents to obtain the simple sol. Sols prepared by adding the alcohol-water-HCl mixture to the precursor were the simple sols presenting a very good stability that permitted the incorporation of powdered P25 without the addition of additives. The composite coatings prepared from these simple sols were the most active in both photocatalytic systems and also presented the highest resistance to scratch.","palabras_clave":"TiO2 |sol-gel"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11680,"idioma_id":5,"titulo":"Agent SocialMetric: una plataforma basada en tecnología web para ambientes de enseñanza y soporte de valoración de conflictos en el aula","resumen":"Actualmente numerosas herramientas de software son utilizadas para asistir a los alumnos y favorecer el aprendizaje en el ámbito educativo. Mediante diversas investigaciones y como resultado del desarrollo de las TICs, fue factible la creación de una herramienta web de desarrollo propio denominada Agent SocialMetric se fundamenta en conceptos que vinculan el Análisis de Redes Sociales (ARS) junto con los Agentes Inteligentes Conversacionales. El objetivo primordial es la asistencia a los docentes brindándole el clima social predominante en el aula a través del agente. En el presente artículo evidenciamos los fundamentos y motivaciones de la propuesta junto con una descripción de la metodología embebida en Agent SocialMetric. Circunscribiendo la aplicación a un caso práctico en el ámbito secundario, se verán las actitudes, los comportamientos específicos de compañeros y las posiciones de éstos en la red social del aula, que influyen en elbullying. Finalmente, brindaremos conclusiones y el trabajo futuro.","palabras_clave":"AGENTES CONVERSACIONALES|ARS|SOCIOMETRÍA|DOCENTES|ÁMBITO ÁULICO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11695,"idioma_id":4,"titulo":"Toxicogenomics: New strategies for ecotoxicology studies in autochthonous species. I. A glade in the entangled path towards the ?fingerprint? of environmental impact?","resumen":"The search for early and sensitive biomarkers pointing to toxic effects of contaminants over organisms, has led the state of art to the molecular mechanisms of signalling, target and response. The trial to obtain more specific biomarkers of response to toxicants was in general biased by the finding of multiple crosstalks between signalling and the transcription factor regulation on gene expression. This may result in virtually impossible application in field ecotoxicological studies and biomonitoring, when native or local species must be used. Molecular biomarkers of toxicity generally show higher sensitivity and precocity in the response, while classical biomarkers such as cholinesterases in organisms exposed to anticholinesterasic agents may show ´inconsistent´ responses. The use of non-model aquatic organisms in general defies the application of commercially available antibodies and implies the design of primers for gene expression studies from model species sequences. The application of transcriptomics has opened a new way to gene annotation and for the design of adequate molecules as tools for the research in new biomarkers in autochthonous species.","palabras_clave":"Biomarkers|Aquatic toxicology|Gene expression regulation|transcriptomics"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11703,"idioma_id":4,"titulo":"Reverse Hölder Property for Strong Weights and General Measures","resumen":"We present dimension-free reverse H'older inequalities for strong $A^*_p$ weights, $1le p < infty$. We also provide a proof for the full range of local integrability of $A_1^*$ weights. The common ingredient is a multidimensional version of Riesz´s ``rising sun´´ lemma.  Our results are valid for any nonnegative Radon measure with no atoms. For $p=infty$, we also provide a reverse H'older inequality for certain product measures. As a corollary we derive mixed $A_p^*-A_infty^*$ weighted estimates.","palabras_clave":"REVERSE HOLDER INEQUALITY|MUCKENHOUPT  WEIGHTS|MAXIMAL FUNCTIONS|MULTIPARAMETER HARMONIC ANALYSIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11704,"idioma_id":4,"titulo":"Borderline weighted estimates for commutators of singular integrals","resumen":"This paper deals with quantitative weighted estimates for commutators.","palabras_clave":"COMMUTAROS|RUBIO DE FRANCIA EXTRAPOLATION|AP WEIGHTS|HARDY-LITTLEWOOD MAXIMAL OPERATOR"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11705,"idioma_id":4,"titulo":"Maropitant administered orally 2-2.5 hours prior to morphine and dexmedetomidine reduces the incidence of emesis in cats","resumen":"Objectives The main goal of this study was to test the antiemetic effects of maropitant administered orally 2?2.5 h prior to morphine and dexmedetomidine in cats.Methods Eighty-three healthy female cats were randomized to receive maropitant (8 mg orally; n = 39) or no treatment (control; n = 44), 2?2.5 h prior to morphine 0.1 mg\/kg and dexmedetomidine 20 &#956;g\/kg intramuscularly. The incidence of sialorrhea, lip licking, retching and vomiting was recorded after morphine\/dexmedetomidine injection.Results There were no differences between groups in terms of age or weight. The treated group received a mean ± SD dose of maropitant of 2.9 ± 0.6 mg\/kg. The incidence of sialorrhea and lip licking was no different between groups. The incidence of retching (control 36% vs maropitant 13%; P = 0.012) and emesis (control 32% vs maropitant 13%; P = 0.03) were significantly reduced in cats treated with maropitant.Conclusions and relevance Maropitant 8 mg (total dose) administered orally 2?2.5 h prior to morphine and dexmedetomidine significantly reduced, but did not eliminate, the incidences of retching and vomiting. Maropitant did not decrease the occurrence of sialorrhea and lip licking, signs that may be indicative of nausea. Maropitant might be useful for morning administration to prevent emesis in outpatient cats requiring sedation or anesthesia; however, dose regimes or interval of administration might require improvement.","palabras_clave":"Antiemetic|Emesis|Feline|Nausea|Opioid|Premedication"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11735,"idioma_id":4,"titulo":"Exploring the diversity of the root-associated microbiome of Ilex paraguariensis St. Hil (Yerba Mate)","resumen":"Ilex paraguariensis St. Hil. (Yerba Mate) is an important crop for which a decrease in yields associated to unsustainable agricultural practices is well documented. The aim of this study is to investigate the diversity of bacteria and fungi inhabiting roots of Yerba Mate. This is an important pre-requisite for the use of microorganisms inhabiting roots to modulate plant nutrition and health as an ecologically friendly agricultural alternative for this crop. The diversity of the root-associated microbiome from eleven plantations with different agricultural practices was analyzed by high throughput sequencing of the 16S rRNA gene as a bacterial marker, whereas the fungal communities were targeted by amplifying the ITS region of the ribosomal RNA gene cluster. A comparison of the bacterial and fungal communities between plantation sites and cultivation practices was made to address the major factors contributing to the structure of the root microbiome of this crop. Operational taxonomic units (OTUs) related to well-known plant growth promoting bacteria such as Burkholderia, Bradyrhizobium, Weissella, Enterobacter and Rhizobium were detected. Those might constitute targets for future enrichment efforts of plant growth promoting clades. The analysis of the fungal community composition demonstrated that arbuscular mycorrhizae colonize Yerba Mate roots, and that the frequency of this group is favored in degraded soils. The detection of other groups harboring potential phytopathogens might help to broaden the understanding of the ailments affecting this crop. This study provides the first description of the root-associated microbiome of Yerba Mate and constitutes a stepping-stone towards harnessing the role of microbes in the sustainable cultivation of this crop.","palabras_clave":"MYCHORRIZAE|PLANT GROWTH|MATE|BUKOLDHERIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11750,"idioma_id":4,"titulo":"Sperm pre-treatment with heparin and L-glutathione, sex-sorting, and double cryopreservation to improve intracytoplasmic sperm injection in bovine","resumen":"In bovine, intracytoplasmic sperm injection (ICSI) remains inefficient partially due to low levels of sperm decondensation. The aim of this study was to determine whether the injection of normal size sperm pretreated with heparin (Hep) and l-glutathione (GSH), the use of sex-sorted sperm, the double round of sperm freezing\/thawing (re frozen), or the combination of these approaches can improve sperm decondensation and embryo development after ICSI in cattle. Cleavage and blastocyst rates were evaluated on days 2 and 7 post ICSI. Quality of ICSI blastocysts was analyzed by the relative expression of four genes by qPCR and the DNA fragmentation index by TUNEL assay. For all assays, semen samples were co-incubated with pCX-EGFP 50 ng\/&#956;l before ICSI. GFP expression, which can be detected by fluorescence microscopy, was used as a tool to estimate the success of sperm decondensation after ICSI. The use of normal size sperm pretreated with 80 &#956;M Hep-15 mM GSH for 20 h (Hep-GSH) increased cleavage, blastocyst and EGFP + blastocysts rates (60.8, 19.4 and 61.9%) compared to control ICSI (35, 4.9 and 20%) (p < 0.05). Moreover, HMGN1, GLUT5, AQP3 and POU5F1 transcription levels did not differ between ICSI Hep-GSH and IVF embryos. The use of sex-sorted sperm (X, Y) improved cleavage rates and EGFP expression at day 4 (83 and 30.2% for ICSI Y and 83.2 and 31.7% for ICSI X) compared to non-sorted group (50.9 and 15.1%), not showing differences at the blastocyst stage. Finally, sex sorting (X) was combined with Hep-GSH and\/or re frozen treatments. The use of Hep-GSH diminished cleavage rates from ICSI X re frozen group (80.4% vs. 94.2%) and blastocyst development from ICSI X group (3.3% vs. 10%), compared with their controls (p < 0.05). While Hep-GSH pretreatment induced lower transgene expression at day 4, no differences were found at the blastocyst stage between ICSI groups (from 58.3 to 80%). TUNEL assay showed higher DNA fragmentation indexes for all ICSI treatments (p < 0.05), except for ICSI X Hep-GSH, which did not differ from IVF X control. In conclusion, the use of normal size sperm pretreated with Hep-GSH, combined or not with sex-sorting by flow cytometry could improve ICSI outcomes in cattle.","palabras_clave":"ICSI|CATTLE|SPERM DECONDENSATION FAILURE|PCX-EGFP"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11756,"idioma_id":5,"titulo":"Las condiciones laborales de las y los enfermeros en Argentina: entre la profesionalización y la precariedad del cuidado en la salud","resumen":"El análisis de las ?ocupaciones del cuidado? ha cobrado creciente relevancia en la agenda feminista de los últimos años. Estas ocupaciones ? mayormente concentradas en los sectores de la salud, la educación y el servicio doméstico ? se encuentran altamente feminizadas y generan oportunidades de empleo para muchas mujeres. No obstante, las mismas presentan en general condiciones de trabajo relativamente pobres, dado que el cuidado suele asociarse a habilidades supuestamente femeninas, socialmente devaluadas en cuanto ?auténtico trabajo?. A su vez, las condiciones laborales deficientes, entre ellas los magros salarios, ponen en cuestión la calidad de los servicios de cuidado provistos. El presente artículo, en base al caso argentino, propone un análisis comparativo sobre un conjunto seleccionado de estas ocupaciones, entre las que se cuentan la enfermería, la docencia inicial y primaria y las trabajadoras domésticas. Si bien estas ocupaciones comparten ciertas vulnerabilidades asociadas a su contenido de cuidado, sus condiciones laborales presentan variaciones significativas. A partir de esta situación, el objetivo central que se plantea el trabajo es el de ahondar en el conocimiento de los factores que actúan atenuando o reforzando la desvalorización social y económica de este tipo de ocupaciones. El propósito último es el de generar reflexiones sobre los aspectos susceptibles de ser abordados por la política pública en pos de mejorar la situación laboral de las y los trabajadores involucrados y, por ende, de los servicios de cuidado provistos.","palabras_clave":"Enfermería|Condiciones de trabajo|Cuidado|Género"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11757,"idioma_id":4,"titulo":"A comparison between maropitant and metoclopramide for the prevention of morphine-induced nausea and vomiting in dogs","resumen":"Morphine is widely used as a preanesthetic agent in dogs, but it often produces signs of nausea and vomiting. Maropitant (MRP) and metoclopramide (MCP) prevent emesis attributable to the opioid agent apomorphine in dogs. We evaluated the antiemetic efficacy and the discomfort in response to SQ injection of MRP [1 mg\/kg body weight (BW)], MCP (0.5 mg\/kg BW), and normal saline (SAL; 0.1 mL\/kg BW) administered to 63 dogs, 45 minutes prior to morphine (0.5 mg\/kg BW) and acepromazine (0.05 mg\/kg BW). Dogs were observed for signs of nausea (ptyalism, lip licking, and increased swallowing) and vomiting for 30 minutes after morphine\/acepromazine. The incidence of emesis was 0% for MRP, 38% for MCP, and 71% for SAL (P < 0.001). The incidence of signs of nausea was not different between groups. Discomfort due to injection was higher after MRP (48%), than after MCP (9.8%) and SAL (4.8%) (P < 0.001).","palabras_clave":"Maropitant|Morphine|Metoclopramide|Vomiting"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11758,"idioma_id":5,"titulo":"CARACTERÍSTICAS DE LAS TEMPERATURAS EXTREMAS EN BUENOS AIRES MEDIANTE REGISTROS CENTENARIOS. ESTUDIO DE LAS CONDICIONES INVERNALES","resumen":"El estudio de las condiciones climáticas en la ciudad de Buenos Aires es de gran importancia dada la población que habita en la misma. Las temperaturas extremas tienen un gran impacto en la provisión de servicios lo que implica la necesidad de un diagnóstico de las mismas para diversas aplicaciones. Las series de Observatorio Central Buenos Aires por su calidad han sido elegidas para este estudio verificando que representan una gran área de influencia que abarca una superficie mayor que la de la ciudad. Los registros que se emplean en este trabajo cubren en algunas escalas desde mitad del siglo XIX y en particular en escala diaria el período 1909-2013. Se estudia la evolución de las temperaturas a lo largo del siglo, centrándose principalmente en el semestre frío. Se define un estado natural de la serie correspondiente a los primeros 20 años del registro en donde ambas series no presentan una tendencia lineal significativa. Valores de corte son definidos en base al estado natural para estudiar diferentes propiedades de los semestres fríos. La duración de los mismos en cuanto a las temperaturas máximas sufrió una disminución de 30 días, mientras que en las mínimas 53 días. La amplitud de los armónicos anuales sufre variaciones, en las máximas se observa una tendencia lineal negativa, mientras que en las mínimas es positiva. Estos resultados están mostrando la existencia de una variabilidad interanual de la variabilidad intranual. Los análisis realizados a las series centenarias permiten reconstruir a las mismas según un estado natural o un estado antropogénico.","palabras_clave":"TEMPERATURA|CENTENARIO|INVIERNO|EXTREMOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11882,"idioma_id":4,"titulo":"Antibacterial synergism of extracts from climbers belonging to Bignoniaceae family and commercial antibiotics against multi-resistant bacteria","resumen":"The objective of this work was to study the effect of interactions between four extracts of climbers belonging to the Bignoniaceae family and commercial antibiotics against multi-resistant pathogenic bacteria and to identify the main antibacterial compounds in the most active extract. The plant species tested were Adenocalymma marginatum, Amphilophium vauthieri, Cuspidaria convoluta and Fridericia caudigera. Synergy between the plant extracts with ampicillin, gentamicin and oxacillin was studied by the checkerboard assay method against multi-resistant Staphylococcus strains and Gram negative bacteria. A synergistic effect was observed in all extracts. The F. caudigera leaf extracts were most active. The main antibacterial compounds present in these extracts were isolated and identified by UV?VIS spectra and HPLC\/MS\/MS. Three main active compounds were identified, apigenin, chrysin and luteolin. Our results indicated that the combinations of species extracts of Bignoniaceae family and commercial antibiotics could be useful in the treatment of many infectious diseases caused by multi-resistant bacteria. In addition, the results highlighted the potential phyto-therapeutic of a total set of phytochemical compounds within a single plant","palabras_clave":"Antibacterial activity|Apigenin|Fridericia caudigera|Luteolin"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11891,"idioma_id":5,"titulo":". Profile mineral grassland Andropogon lateralis Nees and Sorghastrum setosum (Griseb.) Hitchc. in Corrientes, Argentina","resumen":"The goal of this work was to determine the floristic composition and the mineral contribution of Andropogon lateralis Nees (PAL) and Sorghastrum setosum (PSS) pastures, in the animal diet for the production of beef, analyzed by ICP-AES spectrometry in two series of soils from the Province of Corrientes, Argentina. The greatest contribution of dry raw matter is provided by A. lateralis and S. setosum. The contribution of legume is low. The profile of essential mineral elements, probably essential ones and of those of uncertain function, partially fulfill the meat producer cattle requirements. The elemental ratios Ca\/P, Na\/K (mEq), Cu\/Mo and Cu\/Fe, are acceptable. The K\/Mg, K\/Ca+Mg (mEq) and Na\/Mg (mEq) ratios are not adequate, and there is Mg deficiency.","palabras_clave":"Andropogon lateralis  |Floristic composition |Sorghastrum setosum |mineral contribution"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11894,"idioma_id":5,"titulo":"'Rengo es el que tiene pelotas': discapacidad motriz, deporte adaptado y masculinidad hegemónica en la Ciudad de Buenos Aires","resumen":"En este artículo se analiza el rol de la masculinidad hegemónica en el campo del deporte para personas con discapacidad motriz de la Ciudad de Buenos Aires, Argentina. Para ello se parte de los datos recogidos en una investigación cualitativa realizada en dicha ciudad. Se trata de análisis de contenido de prensa escrita producida por los fundadores locales del deporte adaptado, 21 entrevistas en profundidad a hombres usuarios del campo y 26 entrevistas en profundidad a expertos.Entre los principales resultados se halla que la masculinidad hegemónica posee un papel nodal en la filosofía del deporte adaptado. A través de la inculcación de un peculiar modo de comprender a la discapacidad -asociado a la categoría nativa rengo- se promueve una cultura del campeón tributaria del cuerpo capaz y de los valores asociados a la masculinidad hegemónica. Se concluye indicando que si bien dicha cultura cuestiona el carácter estigmatizador de la discapacidad (la presunta incapacidad sexual, la improductividad y la dependencia) impone una ideología de la capacidad que reproduce las estructuras sociales que oprimen a las personas con discapacidad.","palabras_clave":"DISCAPACIDAD|MASCULINIDAD HEGEMONICA|DEPORTE ADAPTADO|IDEOLOGIA DE LA CAPACIDAD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11972,"idioma_id":4,"titulo":"Morphological and molecular characterisation of an isolate of Steinernema diaprepesi Nguyen & Duncan, 2002 (Rhabditida: Steinernematidae) from Argentina and identification of its bacterial symbiont","resumen":"Entomopathogenic nematodes of the families Heterorhabditidae Poinar, 1976 and Steinernematidae Chitwood &amp; Chitwood, 1937 are used for biological control of insect pests. An isolate of Steinernema diaprepesi Nguyen &amp; Duncan, 2002 was recovered from a carrot field in the locality of Santa Rosa de Calchines (Santa Fe Province, Argentina). These nematodes were characterised based on morphological, morphometric and molecular studies. Their symbiotic bacterium was identified as Xenorhabdus doucetiae Tailliez, Pagès, Ginibre &amp; Boemare, 2006 by sequencing the 16S rRNA gene. The isolate of S. diaprepesi studied exhibits some morphometric differences with the original description, especially in the firstgeneration adults. This is the first description of the species in Argentina.","palabras_clave":"STEINERNEMA|NEMATODA|ARGENTINA|TAXONOMY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":11973,"idioma_id":4,"titulo":"The Future of Mathematics in Economics: A Philosophically Grounded Proposal","resumen":"The use of mathematics in economics has been widely discussed.The philosophical discussion on what mathematics is remains unsettled on why it can be applied to the study of the real world. We propose to get back to some philosophical conceptions that lead to a language-like role for the mathematical analysis of economic phenomena and present some problems of interest that can be better examined in this light. Category theory provides the appropriate tools for these analytical approach.","palabras_clave":"Foundations of Mathematics|Mathematical Economics"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12005,"idioma_id":5,"titulo":"?Cantando al patrimonio??  Políticas culturales y expresiones musicales indígenas en Argentina","resumen":"Nuestro objetivo es analizar el impacto de las políticas culturales orientadas a promocionar las expresiones musicales indígenas en dos provincias del norte de Argentina, Jujuy y Formosa, caracterizadas por poseer una alta proporción de población indígena. La metodología articula el análisis de fuentes documentales (legislaciones, programas y medios de difusión de organismos públicos provinciales y nacionales del área de ?cultura?), con el trabajo de campo etnográfico con músicos pertenecientes a los grupos tobas o qom de Formosa y collas de Jujuy, durante los años 2003-2015. Nos centramos en el análisis comparativo de dos casos paradigmáticos: uno de los primeros ?cantos de copla? colla, que se reapropia explícitamente de la noción de ?patrimonio?, creando un canto dedicado especialmente a ese tema, grabado en 2007 por Cresencio Cardozo; y por otro, los cantos de Ema Cuañeri, una de las primeras artistas qom que, según sus definiciones, se ha dedicado a ?la recuperación histórica del canto del pueblo qom?. y de la cosmovisión de sus ancestros?, y que graba en 2005 su primer CD. Las conclusiones apuntan a mostrar cómo el diseño de estas políticas culturales provinciales, ha sido fuertemente influenciado por los discursos globales de promoción del ?multiculturalismo? y de ?preservación del patrimonio cultural tangible e intangible?; sin embargo, en su implementación práctica, son atravesados por modalidades locales caracterizadas por la improvisación e imprevisibilidad en la gestión cultural, en tanto esta última es fuertemente dependiente de factores políticos coyunturales y prácticas clientelares.","palabras_clave":"PATRIMONIO|POLITICA CULTURAL|MUSICAS|INDIGENAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12017,"idioma_id":4,"titulo":"Activity coefficients at infinite dilution of hydrocarbons in glycols: experimental data and thermodynamic modeling with the GCA-EoS","resumen":"The infinite dilution activity coefficients for 12 non-polar hydrocarbon solutes in the solvents, monoethylene and diethylene glycol, were measured using the gas-liquid chromatography technique. Pre-saturation of the carrier gas was required to avoid solvent loss from the chromatographic column during the measurements that were carried out at T = (303.15, 313.15 and 323.15) K for monoethylene glycol and at T = (304.15, 313.15 and 323.15) K for diethylene glycol. The solutes investigated include n-alkanes, 1-alkenes, and cycloalkanes. The new data are compared with the highly scattered data that is available in the open literature. Finally, these highly non-ideal systems are modeled with the GCA-EoS.","palabras_clave":"glycols|GCA-EoS|hydrocarbons|activity coefficients"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12035,"idioma_id":4,"titulo":"New species of Bulbostylis Kunth (Cyperaceae) from South America","resumen":"During the revision of the genus Bulbostylis for Brazil four new species were found, which are proposed here. Bulbostylis amazonica, B. decidua, B. minensis and B. wanderleyana are fully described, illustrated, and compared to other SouthAmerican species.","palabras_clave":"Bulbostylis|taxonomy|Brazil|Cyperaceae"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12051,"idioma_id":4,"titulo":"Thinning of loblolly pine plantations in subtropical Argentina: impact on microclimate and understory vegetation","resumen":"Dur­ing the last three decades, the area ded­i­cated to tree plan­ta­tions in north­east of Ar­gentina has in­creased five-fold at the ex­pense of the na­tive semi­de­cid­u­ous At­lantic For­est. Sil­vi­cul­tural prac­tices such as thin­ning af­fect the un­der­story and for­est floor in­cre­ment­ing veg­e­ta­tion cover and di­ver­sity that may im­pact eco­log­i­cal func­tions such as car­bon and nu­tri­ent cy­cling and pro­vide food and shel­ter for wildlife. The aim of this study was to as­sess the ef­fects of two thin­ning in­ten­si­ties (50% and 30% of in­di­vid­ual re­moval), and lit­ter re­moval in the 50% thin­ning treat­ment on the un­der­story veg­e­ta­tion of loblolly pine (Pi­nus taeda L.). The high thin­ning in­ten­sity and the con­trol with­out thin­ning were in­tended to recre­ate ex­ist­ing man­age­ment prac­tices in the re­gion. The study was car­ried out in three Pi­nus taeda plan­ta­tions (repli­cates). En­vi­ron­men­tal con­di­tions and cover of na­tive un­der­story veg­e­ta­tion were mea­sured dur­ing two years af­ter thin­ning. Canopy open­ness, so­lar ra­di­a­tion, air tem­per­a­ture and soil bulk den­sity were higher in thin­ning treat­ments than in con­trol plots while soil wa­ter con­tent was lower. Veg­e­ta­tion cover and rich­ness in­creased with in­ten­sity of the thin­ning treat­ments. Tree saplings dif­fered in the re­sponses ac­cord­ing to light re­quire­ments and height. Light-de­mand­ing species and in­di­vid­u­als taller than 0.5 m were re­spon­sive to thin­ning in­creas­ing cov­er­age, abun­dance and height, while smaller saplings were more abun­dant in con­trol plots. No ef­fects of lit­ter re­moval were ob­served in un­der­story species rich­ness and plant cover. This study pro­vides ev­i­dence that thin­ning on pine plan­ta­tions in North­east­ern Ar­gentina can con­tribute in main­tain­ing bio­di­ver­sity and re­lated ecosys­tem func­tions of sub­trop­i­cal forests. Man­age­ment prac­tices in­volv­ing lower plan­ta­tion den­si­ties and fewer in­ter­ven­tions should be de­vel­oped to achieve more pos­i­tive ef­fects.","palabras_clave":"THINNING MANAGEMENT |UNDERSTORY VEGETATION|SPECIES AND FUNCTIONAL DIVERSITY|ATLANTIC FOREST"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12069,"idioma_id":5,"titulo":"Reinterpretando la Responsabilidad Ambiental por Daños a las Personas derivados de Actividades Riesgosas: el caso de los Contratos Agroindustriales","resumen":"Los contratos agroindustriales se han propagado velozmente en los últimos años como instrumentos de coordinación y control de la producción primaria destinada a industrialización, convirtiéndose en piezas claves para el funcionamiento de ciertos subsectores económicos. De manera simultánea se percibe un crecimiento notable de conflictos ambientales que comprenden casos graves de daños sufridos por personas, animales y el ambiente, en el marco del desarrollo de estos esquemas productivos.Dado que uno de los rasgos más característicos y novedosos de los contratos agroindustriales utilizados en estos esquemas es el traslado de las facultades de dirección y control sobre el proceso productivo primario desde el agricultor hacia el empresario integrador (o industrial), nos propusimos repensar la situación en que se encuentra éste último cuando el primero ocasiona daños ambientales indirectos como consecuencia de la ejecución de actividades riesgosas. Siguiendo los criterios provistos por el nuevo bloque de legalidad, reinterpretamos el sistema tradicional de responsabilidad civil basado en el art. 1758 in fine CCCN, concluyendo que resulta posible extender la responsabilidad al sujeto servido por la actividad riesgosa, derive o no provecho económico de ella, es decir, con independencia de su calidad de aprovechador de la misma. Por los fundamentos expuestos, entendemos que la lectura propuesta de la norma se adecua mejor al principio constitucional de prevención del daño ambiental y a la función preventiva asignada al régimen de responsabilidad del CCCN, siendo por ella superadora de la versión clásica o tradicional.  Asimismo, desde el punto de vista axiológico, la interpretación sugerida puede considerarse valiosa toda vez que evita la situación injusta que se genera cuando la responsabilidad por daño ambiental indirecto se limita al sujeto que si bien ejecutó la acción dañosa, lo hizo en cumplimiento de las órdenes o directivas impartidas por el empresario, o cuanto menos bajo su supervisión, aunque no exista relación de dependencia laboral o control societario","palabras_clave":"CONTRATOS AGROINDUSTRIALES|DAÑOS AMBIENTALES|RESPONSABILIDAD POR ACTIVIDADES RIESGOSAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12080,"idioma_id":4,"titulo":"Phenotypic plasticity in freshwater picocyanobacteria","resumen":"Picocyanobacteria can occur as single-cell (Pcy) or as colonies (CPcy). Published evidence suggests that some Pcy strains have the capability to aggregate under certain culture conditions, however this has not been demonstrated to occur in natural environments. We investigated whether the Pcy and CPcy belong to the same species (i.e. phylotype), and the factors that determine their morphological and genetic variability in a hypertrophic shallow lake dominated by picocyanobacteria. Six main different morphologies and >30 phylotypes were observed. All sequences retrieved belonged to the ?Anathece + Cyanobium? clade (Synechococcales) that are known to have the capability of aggregation\/disaggregation. The temporal variation of picocyanobacteria morphotype composition was weakly correlated with the DGGE temporal pattern, and could be explained by the composition of the zooplankton assemblage. Laboratory experiments confirmed that the small cladoceran Bosmina favoured the dominance of CPcy, i.e. Cyanodictyon doubled the size of the colonies when present, most likely through the aggregation of single-cell picocyanobacteria into colonies. Flow cytometry cell sorting and 16S rRNA + ITS sequencing of the Pcy and CPcy cytometrically-defined populations revealed that some phylotypes could be found in both sorted populations, suggesting phenotypic plasticity in which various Synechococcales phylotypes could be found in situ either as single-cells or as colonies.","palabras_clave":"Synechococcales|16S rRNA|ITS|grazing|zooplankton|sorting|flow cytometry"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12101,"idioma_id":5,"titulo":"Actividad geomorfológica y colonización vegetal en depósitos de abanicos aluviales del desierto del Monte Central de Argentina","resumen":"Se realizó un análisis geomorfodinámico del piedemonte occidental de la sierra Chica de Zonda, en la Precordillera Oriental de Argentina. La metodología utilizada fue una combinación de herramientas tradicionales, como la interpretación de fotografías aéreas y el análisis de imágenes satelitales, y un análisis exhaustivo de depósitos y de la vegetación mediante trabajo en campo. El objetivo de este estudio es identificar y clasificar los depósitos de abanicos aluviales de piedemonte teniendo en cuenta la acción de procesos morfodinámicos y establecer su efecto sobre las comunidades de vegetaciónnativa. Los resultados permitieron identificar dos grandes unidades morfodinámicas en los abanicos aluviales: a) depósitos activos actuales y b) depósitos inactivos antiguos. La cobertura de la vegetación asociada a estos depósitos muestra una diferencia significativa (p=0.034), la diversidad y riqueza de especies varían de acuerdo con los procesos que actúan en los sectores de abanicos aluviales. Durante el período Cuaternario, en esta área se produjeron algunos cambios en los procesos dinámicos, lo que provocó el desarrollo de al menos dos ciclos de depósito de los flujos de carga con una relación diferente entre sólidos y líquidos. En la actualidad, estos diferentes depósitos de abanicos aluviales están sujetos a diversos procesos dinámicos que influyen en las características de la colonización y la distribución de lasplantas nativas. La vegetación se distribuye en relación con el tipo de depósito en el que crece, sin embargo, también depende de la dinámica de los procesos que tienen lugar en las unidades geomorfológicas. La identificación y análisis de los procesos geomorfológicos son importantes para determinar la cobertura y la distribución de la vegetación en abanicos aluviales de zonas áridas.","palabras_clave":"MORFODINÁMICA|VEGETACIÓN|GEOMORFOLOGÍA|RELACIÓN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12133,"idioma_id":4,"titulo":"The conformation-independent QSPR approach for predicting the oxidation rate constant of water micropollutants","resumen":"In advanced water treatment processes, the degradation efficiency of contaminants depends on the reactivity of the hydroxyl radical toward a target micropollutant. The present study predicts the hydroxyl radical rate constant in water (kOH) for 118 emerging micropollutants, by means of quantitative structure-property relationships (QSPR). The conformation-independent QSPR approach is employed, together with a large number of 15,251 molecular descriptors derived with the PaDEL, Epi Suite, and Mold2 freewares. The best multivariable linear regression (MLR) models are found with the replacement method variable subset selection technique. The proposed five-descriptor model has the following statistics for the training set: (Formula presented.), RMStrain = 0.21, while for the test set is (Formula presented.), RMStest = 0.11. This QSPR serves as a rational guide for predicting oxidation processes of micropollutants.","palabras_clave":"Reaction Rate Constant|Water Micropollutant|Quantitative Structure- Property Relationships|Replacement Method|Molecular Descriptors"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12143,"idioma_id":5,"titulo":"El aprendizaje de la identidad profesional. Expresiones sobre el aprendizaje para el trabajo","resumen":"IntroducciónLa identidad profesional se construye y tiene lugar en la interrelación entre la agencia individual y las sugerencias de prácticas en los lugares de trabajo. Se considera que la identidad se construye en la intersección de lo social y lo individual, a partir de los lugares de participación, los materiales y experiencias con los que la persona construye una imagen del mundo y de sí mismo.ObjetivoExplorar la construcción de la identidad profesional de los estudiantes en el interjuego de diferentes contextos de aprendizaje.MetodologíaLos datos fueron tomados a partir de entrevistas realizadas a los participantes de un taller de producción periodística en el año 2015, perteneciente a las carreras Tecnicatura en Periodismo y Licenciatura en Comunicación Social de la Universidad Nacional de Villa María.ResultadosEntre los resultados obtenidos, puede decirse que el desarrollo de problemas genuinos encuentra relación con la identidad profesional que desarrollan los estudiantes, precisamente la cobertura de eventos y la búsqueda de noticias da cuenta de la identidad profesional que se va forjando desde las primeras prácticas a partir de la generación de lugares y propuestas de participación que encuentran interacción con el mundo del trabajo y promueven el aprendizaje de habilidades propias de la profesión.Discusión Los resultados obtenidos permiten repensar los planteos que la Psicología Educativa está reflexionando en términos de abrir a nuevos temas y atender al aprendizaje fuera de la escuela y en el mundo del trabajo.","palabras_clave":"APRENDIZAJE|IDENTIDAD|CONTEXTOS|PSICOLOGIA EDUCATIVA|PSICOLOGÍA LABORAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12148,"idioma_id":5,"titulo":"La demanda familiar de Apoyo Pedagógico en Educación Secundaria","resumen":"Introducción Con la intención de dar a conocer las demandas educativas que acontecen fuera de la escuela, este escrito expone sobre las particularidades de las clases de apoyo pedagógico, como instancia educativa que emerge del entrecruzamiento entre los contextos formales y no formales de aprendizaje y en la cual se establece una relación de refuerzo y colaboración. Objetivos El estudio apunta a reconocer las demandas familiares de apoyo pedagógico en Primer Año de Educación Secundaria. Metodología Se realizaron 15 entrevistas en profundidad a familiares de estudiantes que asistieron a clases de apoyo y a diferentes agentes educativos de un colegio secundario de un pueblo del sur cordobés. Resultados En relación a los datos analizados, podemos decir que una de las principales funciones demandadas al apoyo pedagógico consiste en el afianzamiento de las temáticas incluidas en las evaluaciones. Las actividades que se demandan del apoyo escolar, están vinculadas a contenidos académicos brindados desde la educación formal y varían en relación a los emergentes de los estudiantes.DiscusiónEste estudio permite pensar en las clases de apoyo pedagógico, como una modalidad que transita la educación fuera de la escuela y en la configuración que dicho servicio adquiere, como un contexto de educación que se construye a modo de  fortalecer oportunidades de aprendizaje.","palabras_clave":"APRENDIZAJE|CONTEXTOS DE APRENDIZAJE|APOYO PEDAGÓGICO|EDUCACIÓN SECUNDARIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12159,"idioma_id":4,"titulo":"The role and place of commodity fetishism in Marx?s systematic-dialectical exposition in Capital","resumen":"This article aims to contribute to the literature on Marx?s systematic-dialectical method through a critical reading and discussion of the significance and presentational ?architecture? of the section on commodity fetishism in the dialectical sequence of form determinations in Capital. In order to undertake this task, the paper firstly explores the content and expositional structure of the first three sections of Chapter 1 of Capital. This sets the stage for a methodologically-minded close examination of Marx?s presentation of the fetish character of the commodity, which shows that there is a precise systematic sequence which gives unity to the flow of his argument within the section on ?The Fetishism of the Commodity and its Secret?. Particular attention is given to Marx?s investigation of the commodity form as entailing both the most general form of objectivity and subjectivity of the capitalist mode of production. The conclusion is that only through a proper grasp of the dialectical method can the full systematic significance and implications of Marx?s account of commodity fetishism be uncovered.","palabras_clave":"Marx|Commodity Fetishism|Dialectical Method|Critique of Political Economy"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12195,"idioma_id":4,"titulo":"Transient spectroscopic characterization and theoretical modeling of fulvic acid radicals formed by UV-A radiation","resumen":"Laser flash-photolysis experiments (lambda exc = 355 nm) performed with aqueous solutions of Pony Lake and Waskish Peat fulvic acids at pH=2 showed formation of transient species with absorption maxima at 470-480 nm with O2-independent lifetimes of 600-700 us, which were assigned to a phenoxyl radicals. Formation of these radicals occurs after photoionization of the fulvic acids followed by fast deprotonation process. Photoacoustic experiments at the same excitation wavelength yielded the O2-independent fraction of energy stored at times longer than 135 ns. DFT calculations were performed to estimate the absorption spectra and energy content of the phenoxyl radicals and triplet excited state of the Buffle model of the fulvic acid. Combination of the DFT and photoacoustic data yielded the photoionization quantum yields of both FA, which were compared to reported values obtained by steady-state and time-resolved techniques.","palabras_clave":"FULVIC ACID|LASER FLASH PHOTOLYSIS|PHOTOACUSTICS|DENSITY FUNCTIONAL THEORY|PHENOXYL RADICALS|TRIPLET STATES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12205,"idioma_id":4,"titulo":"The Interatheriinae from the Late Oligocene of Mendoza (Argentina), with comments on some Deseadan Interatheriidae","resumen":"This contribution discusses the interatheriids from Quebrada Fiera, a Late Oligocene locality in the south of Mendoza Province. In addition, the taxonomic status of the Deseadan interatheres Plagiarthrus clivus, Argyrohyrax proavus, Argyrohyrax proavunculus, ?Argyrohyrax acuticostatus, Progaleopithecus fissurelatus, Progaleopithecus tournoueri, and Notohyrax conicus is discussed. We recognise in Quebrada Fiera A. proavus and Progaleopithecus sp. A possible third taxon is represented by one specimen that shows a combination of features that do not permit accurate assignment. These new remains, in combination with a systematic study of Deseadan interatheres, allow for a better definition of each recognised taxon, extended diagnoses, and clarification of some long-standing taxonomic misconceptions. Indeed, the priority of A. proavus over P. clivus is established, and the latter is proposed as a nomen dubium. Associated deciduous and permanent dentition and some limb bones provide new data on the ontogenetic variation and postcranial morphology of Argyrohyrax. Phylogenetic analysis supports the taxonomic determinations and places A. proavus in a basal position with respect to Archaeophylus or Progaleopithecus. Documented fossil records of Argyrohyrax and Progaleopithecus in Mendoza extend the known range to middle latitudes in central west Argentina; these taxa expand the list of mammals from Quebrada Fiera with Patagonian affinities.","palabras_clave":"INTERATHERES|DESEADAN|QUEBRADA FIERA|PATAGONIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12253,"idioma_id":4,"titulo":"A structural equation modeling of executive functions, IQ and mathematical skills in primary students: Differential effects on number production, mental calculus and arithmetical problems","resumen":"Though the relationship between executive functions (EFs) and mathematical skills has been well documented, little is known about how both EFs and IQ differentially support diverse math domains in primary students. Inconsistency of results may be due to the statistical techniques employed, specifically, if the analysis is conducted with observed variables, i.e., regression analysis, or at the latent level, i.e., structural equation modeling (SEM). The current study explores the contribution of both EFs and IQ in mathematics through an SEM approach. A total of 118 8- to 12-year-olds were administered measures of EFs, crystallized (Gc) and fluid (Gf) intelligence, and math abilities (i.e., number production, mental calculus and arithmetical problem-solving). Confirmatory factor analysis (CFA) offered support for the three-factor solution of EFs: (1) working memory (WM), (2) shifting, and (3) inhibition. Regarding the relationship among EFs, IQ and math abilities, the results of the SEM analysis showed that (i) WM and age predict number production and mental calculus, and (ii) shifting and sex predict arithmetical problem-solving. In all of the SEM models, EFs partially or totally mediated the relationship between IQ, age and math achievement. These results suggest that EFs differentially supports math abilities in primary-school children and is a more significant predictor of math achievement than IQ level.","palabras_clave":"EXECUTIVE FUNCTIONS|INTELLIGENCE|MATHEMATICS|STRUCTURAL EQUATION MODELING"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12273,"idioma_id":4,"titulo":"Biochemical Characterization of beta-Lactamases from Mycobacterium abscessus Complex and Genetic Environment of the beta-Lactamase-Encoding Gene","resumen":"The objectives of this study were to determine the kinetic parameters of purified recombinant BlaMab and BlaMmas by spectrophotometry, analyze the genetic environment of the blaMab and blaMmas genes in both species by polymerase chain reaction and sequencing, furthermore, in silico models of both enzymes in complex with imipenem were obtained by modeling tools. Our results showed that BlaMab and BlaMmas have a similar hydrolysis behavior, displaying high catalytic efficiencies toward penams, cephalothin, and nitrocefin; none of the enzymes are well inhibited by clavulanate. BlaMmas hydrolyzes imipenem at higher efficiency than cefotaxime and aztreonam. BlaMab and BlaMmas showed that their closest structural homologs are KPC-2 and SFC-1, which correlate to the mild carbapenemase activity toward imipenem observed at least for BlaMmas. They also seem to differ from other class A beta-lactamases by the presence of a more flexible Omega loop, which could impact in the hydrolysis efficiency against some antibiotics. A -35 consensus sequence (TCGACA) and embedded at the 3´ end of MAB_2874, which may constitute the blaMab and blaMmas promoter. Our results suggest that the resistance mechanisms in fast-growing mycobacteria could be probably evolving toward the production of beta-lactamases that have improved catalytic efficiencies against some of the drugs commonly used for the treatment of mycobacterial infections, endangering the use of important drugs like the carbapenems.","palabras_clave":"Bla|carbapenemases|Mycobacterium massiliense"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12282,"idioma_id":4,"titulo":"Evaluation of an action research project by university environmental volunteers.","resumen":"The university volunteer programs in Argentina encourageentrepreneurship culture through the development of innovativesocio-environmental projects that promote a joint effort betweenthe different administrations of the State, the universities andregional social organizations. One, called ?environment and socialinclusion? has been undertaken since 2011 in Stella Maris, a coastalsuburb of the city of Comodoro Rivadavia  Chubut. The programincludes a training phase for the university volunteers, an actionplan addressed to the social agents and an evaluation of the results.This project has contributed to the reduction of vulnerabilities fromthe proposed action research planned by volunteer universitystudents, teachers and social agents. Neighborhood institutionalleaders who actively participated also contributed. Through aparticipatory diagnosis, the different actors in the communitybecame aware of the environmental problems of their area andestablished strategic priorities for action in the short, medium andlong term. The diagnosis itself was a learning process clarifyingattitudes and environmental awareness that predisposed theparticipants to collective action. In our opinion, the next step wouldbe to increase the socialpolitical pressure on the local authoritiesto change the problem tackled into one of its priority actions.","palabras_clave":"Environmental education|coastal management|Vulnerability|volunteering"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12292,"idioma_id":4,"titulo":"Cross neutralization of coral snake venoms by commercial Australian snake antivenoms","resumen":"Context: Although rare, coral snake envenomation is a serious health threat in Brazil, because of the highly neurotoxic venom and the scarcely available antivenom. The major bottleneck for antivenom production is the low availability of venom. Furthermore, the available serum is not effective against all coral snake species found in Brazil. An alternative to circumvent the lack of venom for serum production and the restricted protection of the actually available antivenom would be of great value. We compared the Brazilian coral snake and mono and polyvalent Australian antivenoms in terms of reactivity and protection. Methods: The immunoreactivity of venoms from 9 coral snakes species were assayed by ELISA and western blot using the Brazilian Micrurus and the Australian pentavalent as well as monovalent anti-Notechis, Oxyuranus and Pseudechis antivenoms. Neutralization assays were performed in mice, using 3 LD50 of the venoms, incubated for 30 minutes with 100 &mu;L of antivenom\/animal. Discussion: All the venoms reacted against the autologous and heterologous antivenoms. Nevertheless, the neutralization assays showed that the coral snake antivenom was only effective against M. corallinus, M. frontalis, M. fulvius, M. nigrocinctus and M. pyrrhocryptus venoms. On the other hand, the Australian pentavalent antivenom neutralized all venoms except the one from M. spixii. A combination of anti-Oxyuranus and Pseudechis monovalent sera, extended the protection to M. altirostris and, partially, to M. ibiboboca. By adding Notechis antivenom to this mixture, we obtained full protection against M. ibiboboca and partial neutralization against M. lemniscatus venoms. Conclusions: Our findings confirm the limited effectiveness of the Brazilian coral snake antivenom and indicate that antivenoms made from Australian snakes venoms are an effective alternative for coral snake bites in South America and also in the United States were coral snake antivenom production has been discontinued.","palabras_clave":"Micrurus|Elapid|antivenom|cross neutralization"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12310,"idioma_id":5,"titulo":"LA INVESTIGACIÓN-ACCIÓN COMO ESTRATEGIA PARA RE-VISITAR EXPERIENCIAS, POSICIONAMIENTOS Y PRÁCTICAS ANTE VIOLENCIAS EN ESCUELAS","resumen":"El trabajo explora perspectivas y posicionamientos de agentes educativos ante violencias en escuelas, para expandir la mirada sobre problemas que enfrentan e intervenciones que realizan. Analiza reflexiones de educadores de dos colegios secundarios de la región metropolitana y caracteriza su aprendizaje profesional y apropiación de sentidos en Talleres de Reflexión sobre la Práctica. El estudio es cualitativo, descriptivo y exploratorio. La metodología de investigación-acción retoma conceptos del laboratorio de cambio (Engeström, 2007) para favorecer interacción, polifonía y resignificación del trabajo escolar. Se administraron Cuestionarios de Situaciones Problema de Intervención en Violencias en Escuelas (Erausquin, 2009) y Cuestionarios de Reflexión sobre la Práctica del Taller (Erausquin, Dome, 2014). El análisis de datos utiliza método etnográfico  y análisis de contenido (Bardin, 1986). Los resultados posibilitan identificar fortalezas y nudos críticos de profesionalización, y describir movimientos, cambios y giros en dirección al enriquecimiento de la práctica y la expansión del aprendizaje (Engeström, 2001).","palabras_clave":"PERSPECTIVAS|VIOLENCIAS|INTERVENCIONES|APRENDIZAJE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12333,"idioma_id":4,"titulo":"REVIEW of B.T. Arnold y R.S. Hess (eds.), Ancient Israel's History: An Introduction to Issues and Sources, Grand Rapids, Baker Academic, 2014.","resumen":"Review of Bill T. Arnold and Richard S. Hess (eds.), Ancient Israel?s History: An Introduction to Issues and Sources. Grand Rapids, MI: Baker Academic, 2014. Pp. xv + 544. ISBN 978-0-8010-3930-0.","palabras_clave":"ANCIENT ISRAEL|ANCIENT HISTORIOGRAPHY|HISTORICAL METHODOLOGY|REVIEW"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12347,"idioma_id":4,"titulo":"Hopf braces and Yang-Baxter operators","resumen":"This paper introduces Hopf braces, a new algebraic structure related to the Yang?Baxter equation, which include Rump?s braces and their non-commutative generalizations as particular cases. Several results of classical braces are still valid in our context. Furthermore, Hopf braces provide the right setting for considering left symmetric algebras as Lie-theoretical analogs of braces.","palabras_clave":"Braces|Hopf algebras|Yang-Baxter"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12348,"idioma_id":4,"titulo":"Combined phylogeny of ray-finned fishes (Actinopterygii) and the use of morphological characters in large-scale analyses","resumen":"This paper evaluates the phylogeny of ray-finned fishes (Actinopterygii) combining most available information (44 markers from nuclear and mitochondrial DNA and 274 morphological characters). The molecular partition of the dataset was produced through a pipeline (Gb-to-TNT) that allows the fast building of large matrices from GenBank format. The analyzed dataset has 8104 species, including representatives of all orders and 95% of the 475 families of Actinopterygii, making it the most diverse phylogenetic dataset analyzed to date for this clade of fishes. Analyzed morphological characters are features historically considered diagnostic for families or orders since many years, which can be unequivocally coded from the literature. Analyses are by parsimony under several weighting schemes. General results agree with previous classifications, especially for groups with better gene sampling and those long thought (from morphological evidence) to be monophyletic. Many clades have low support and some orders are not recovered as monophyletic. Additional data and synthetic studies of homology are needed to obtain synapomorphies and diagnoses for most clades.","palabras_clave":"SYSTEMATICS|ICHTHYOLOGY|CLADISTICS|IMPLIED WEIGHTING"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12357,"idioma_id":4,"titulo":"Upper quaternary evolution of the dune &#64257; eld of the Bols\u0001on de Fiambal\u0001a, Catamarca: Sand dispersal at the Andes piedmonts","resumen":"The South American Arid Diagonal extends in Argentina from Puna to Patagonia regions. Several dune fields are scattered between the Andes and Pampas ranges, covering plains and plateaus. One of the northernmost dune fields is occupying the tectonic valley known as Bolsón de Fiambalá. White transverse dunes extend from west to east, climbing to the Fiambalá Range. Some outcrops from the surrounding area are useful to understand the evolution of this dune field. At the Chaschuil valley, a profile composed of 4 m of stratified sands and gravels were sampled at Las Lozas. Epiphytes and benthic diatom assemblages suggest a shallow lake located at 3700 m altitude. Many of these brackish\/freshwater aerophilous taxa tolerate desiccation periods and salt concentration. The assemblages were dominated by Nitzschia frustulum, Nitzschia linearis, Achnanthes thermalis var. rumrichorum, Epithemia adnata, Pinnularia viridis y Nitzschia capitellata. Limestones from this outcrop gave ages of 32,000±520 and 29,380±410 radiocarbon years BP (Garleff et al. 1993), suggesting the Marine Isotopic Stage 3. The Holocene Interglacial is recorded either at the Chaschuil and Abaucán rivers valleys. Lake deposits at 3000 m altitude gave ages between 6175±70 and 2990±70 radiocarbon years BP (Garleff et al. 1993). The sand of this dune field at the northern part of the Bolsón was supplied by the fanglomerates located to the west, at Medanitos. There is also a significant supply of pumicite, derived from the Cerro Blanco volcanic dome. Aridity increase is recorded from archaeological evidences and confirmed by the discharge records of the Abaucán River during the 1919-1957 interval. Although these sand dunes with a high content in volcanic glass clearly derived from the Andes, other sand dunes from central Argentina derived from the deactivation of the Desaguadero-Curacó system.","palabras_clave":"DUNE FIELD|SAND DISPERSAL|FIAMBALA|ARGENTINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12367,"idioma_id":4,"titulo":"Mn-doped ZnS phosphorescent quantum dots: Coumarins optical sensors","resumen":"tMn-doped ZnS quantum dots (QDs) have increasingly attracted much attention as luminescent sensors. Mn+2doping promotes a strong phosphorescence-like emission, allowing the development of noveland highly selective sensing phases. In this vein, a coumarins phosphorescent sensor was developedbased on the room temperature phosphorescence quenching of water-soluble Mn-doped ZnS QDs. Phos-phorescence lifetimes were measured in order to clarify the involved quenching mechanism. Warfarindetermination in pharmaceutical products was performed, reaching good figures of merit. The developedmethodology is an alternative, rapid, simple, sensitive and selective method for coumarins determinationin pharmaceutical and toxicological samples","palabras_clave":"Mn-doped ZnS quantum dots|Room temperature phosphorescence|Coumarins|Quenching"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12377,"idioma_id":4,"titulo":"Climatic niche evolution in the Andean genus Menonvillea (Cremolobeae: Brassicaceae)","resumen":"The study of how climatic niches change over evolutionary time has recently attracted the interest of many researchers. Different methodologies have been employed principally to analyze the temporal dynamics of the niche and specially to test for the presence of phylogenetic niche conservatism. Menonvillea, a genus of Brassicaceae including 24 species, is distributed primarily along the Andes of Argentina and Chile, with some taxa growing in southern Patagonia and others in the Atacama Desert and the Chilean Matorral. The genus is highly diversified morphologically but also presents a remarkably wide ecological range, growing from the high Andean elevations, to the dry coastal deserts in Chile, or the Patagonia Steppe in Argentina. In this study, we used molecular phylogenies together with climatic data to study climatic niche evolution in the genus. The results show that the main climatic niche shifts in Menonvillea occurred between the sections Cuneata-Scapigera and sect. Menonvillea throughout the Mid-Late Miocene, and associated with the two main geographical distribution centers of the genus: the highlands of the central-southern Andes and the Atacama Desert-Chilean Matorral, respectively. Climatic niches in these lineages were mainly differentiated by the aridity and potential evapotranspiration, the minimum temperatures of the coldest month, and the temperature annual range and seasonality. Niche evolution in Menonvillea deviated from a Brownian motion process, with most of the climatic dimension best-fitting to an Ornstein-Uhlenbeck model of multiple adaptive peaks. Our results also indicated that higher aridity levels and lower annual temperature ranges were associated with the evolution of the annual habit, as exemplified by the distribution of sect. Menonvillea. Finally, the results suggested that climatic niche evolution in Menonvillea exhibited some degree of phylogenetic niche conservatism, fundamentally within the two main lineages (sect. Menonvillea and sects. Cuneata-Scapigera).","palabras_clave":"Andes|Atacama desert|Cruciferae|Patagonian Steppe|Phylogenetic niche conservatism|Species distribution modeling"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12397,"idioma_id":4,"titulo":"Stable eutectoid transformation in nodular cast iron: modeling and validation","resumen":"This paper presents a new microstructural model of the stable eutectoid transformation in a spheroidal cast iron. The model takes into account the nucleation and growth of ferrite grains and the growth of graphite spheroids. Different laws are assumed for the growth of both phases during and below the intercritical stable eutectoid. At a microstructural level, the initial conditions for the phase transformations are obtained from the microstructural simulation of solidification of the material, which considers the divorced eutectic and the subsequent growth of graphite spheroids up to the initiation of the stable eutectoid transformation. The temperature field is obtained by solving the energy equation by means of finite elements. The microstructural (phase change) and macrostructural (energy balance) models are coupled by a sequential multiscale procedure. Experimental validation of the model is achieved by comparison with measured values of fractions and radius of 2D view of ferrite grains. Agreement with such experiments indicates that the present model is capable of predicting ferrite phase fraction and grain size with reasonable accuracy.","palabras_clave":"stable eutectoid|ferrite|graphite|cast iron|Thermo-Metallurgical"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12399,"idioma_id":4,"titulo":"Geographic clusters of congenital anomalies in Argentina","resumen":"Abstract Geographical clusters are defined as the occurrenceof an unusual number of cases higher than expected in a givengeographical area in a certain period of time. The aim of thisstudy was to identify potential geographical clusters of specificselected congenital anomalies (CA) in Argentina. The caseswere ascertained from 703,325 births, examined in 133 maternityhospitals in the 24 provinces of Argentina.We used thespatial scan statistic to determine areas of Argentina whichhad statistically significant elevations of prevalence. Prenataldiagnosis followed by referral of high-risk pregnancies to highcomplexity hospitals in a hospital-based surveillance systemcan create artifactual clusters.We assessed the referral bias byevaluating the prevalence heterogeneity within each cluster.Eight clusters of selected CAs with unusually high birth prevalencewere identified: anencephaly, encephalocele, spinabifida, diaphragmatic hernia, talipes equinovarus, omphalocele,Cleft lip with or without cleft palate (CL\/P), and Down syndrome.The clusters of Down syndrome and CL\/P observed inthis study match the previously reported clusters. These findingssupport local targeted interventions to lower the prevalenceof the CAs and\/or further research on the cause of each cluster.The clusters of spina bifida, anencephaly, encephalocele,omphalocele, congenital diaphragmatic hernia, and talipesequinovarus may be influenced by prenatal diagnosis and referralto high complexity hospitals.Keywords Congenital anomalies . Birth prevalence .Geographic clusters . National Network of CongenitalAnomalies of Argentina (RENAC)","palabras_clave":"Birth prevalence; |Congenital anomalies; |Geographic clusters; |National Network of Congenital Anomalies of Argentina (RENAC)"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12400,"idioma_id":4,"titulo":"The impact of unemployment cycles on child and maternal health in Argentina","resumen":"Objectives: The purpose of this study is to examine the effects of economic cycles in Argentina on infant and maternal health between 1994 and 2006, a period that spans the major economic crisis in 1999&ndash;2002. Methods: We evaluate the effects of province-level unemployment rates on several infant health outcomes, including birth weight, gestational age, fetal growth rate, and hospital discharge status after birth in a sample of 15,000 infants born in 13 provinces. Maternal health and healthcare outcomes include acute and chronic illnesses, infectious diseases, and use of prenatal visits and technology. Regression models control for hospital and year fixed effects and province-specific time trends. Results: Unemployment rise reduces fetal growth rate particularly among high educated parents. Also, maternal poverty-related infectious diseases increase, although reporting of acute illnesses declines (an effect more pronounced among low educated parents). There is also some evidence for reduced access to prenatal care and technology among less educated parents with higher unemployment. Conclusions: Unemployment rise in Argentina has adversely affected certain infant and maternal health outcomes, but several measures show no evidence of significant change.","palabras_clave":"Birth weight; |Business cycles; |Economic depression; |Fetal growth;"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12405,"idioma_id":5,"titulo":"De la Sociedad Literaria Deán Funes a la Asociación 'Córdoba Libre'. Dos estaciones del liberalismo y las elites de Córdoba (1878 \/ 1919)","resumen":"El artículo explora dos estaciones de las elites y el liberalismo cordobeses a través de dos asociaciones autodefinidas como culturales y singularmente enlazadas a la vida político-intelectual local y nacional. La Sociedad Literaria Deán Funes (1878\/1883) y la Asociación Córdoba Libre (1916\/ca 1922) son así el prisma para pensar esas estaciones e intentar rozar los procesos más generales que en parte las modularon: la reestructuración de las elites locales, la reorganización de los equilibrios nacionales, la modificación del protagonismo local relativo autorizado por cada momento, la especificación de las diversas zonas de la actividad social y las mutaciones del liberalismo genérico que dominaba el comienzo de la etapa.","palabras_clave":"LIBERALISMO|ELITES|ASOCIACIONES CULTURALES|CÓRDOBA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12413,"idioma_id":4,"titulo":"Configurational Entropy of a Set of Dipoles Placed on a Two-dimensional Lattice.","resumen":"In the present work we calculate the congurational entropy of an arbitrary number of dipoles placed on a square lattice. We use a quasi-two-dimensional (Q2D) space to capture the main features determining the occupation statistics of this system. We show that our result is in agreement with both, lattice-gas predictions at low coverages and the exact value derived in the close-packed limit as well. Therefore our equation provides a substantial improvement to the most recent calculations based on semiempirical models and Monte Carlo simulations.","palabras_clave":"Entropy|Monte Carlo|Adsorption"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12439,"idioma_id":5,"titulo":"SIG arqueológico del Parque Nacional Bosques Petrificados de Jaramillo (Provincia de Santa Cruz, Argentina)","resumen":"El presente trabajo tiene como objetivo presentar la sistematización de la información obtenida a partir de las prospecciones realizadas en el Bosque Petrificado de Jaramillo (Santa Cruz, Argentina), para dar cuenta de la riqueza y potencial arqueológicos del sector. Para ello se confecciona una carta arqueológica y distintos tipos de cartografía temática mediante Sistemas de Información Geográfica, los que en conjunto constituyen herramientas para el análisis y gestión del patrimonio arqueológico.&nbsp;","palabras_clave":"CARTA ARQUEOLOGICA|SIG|CAZADORES-RECOLECTORES|PATAGONIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12446,"idioma_id":5,"titulo":"Expansión reciente de la política de priorización en la investigación científica de las universidades públicas de la Argentina","resumen":"El artículo indaga la emergencia de una agenda y el diseño de  instrumentos de incentivo en torno a la definición estratégica de la investigación científica entre 2007 y 2015 y su incidencia en el ámbito universitario público de la Argentina. A través de un abordaje cualitativo, se llevó a cabo un estudio trasversal de los instrumentos de promoción orientados, financiados con recursos de las propias universidades nacionales y se realizaron entrevistas a autoridades de esta área de políticas. Desde la perspectiva del análisis de políticas públicas, la investigación revela que tanto desde el plano de las ideas de política como desde la configuración instrumental de las normas, las directrices y los instrumentos orientados de las principales agencias del sector -en particular los de la ANPCyT y el CONICET- alcanzaron cierta persuasión en el ámbito universitario local, por lo que la definición de áreas estratégica obtuvo una considerable expansión en el mapa reciente de las políticas científicas de las universidades nacionales. Palabras clave: universidades públicas; política científica, investigación científica; política universitaria; Argentina.","palabras_clave":"UNIVERSIDADES PÚBLICAS|POLÍTICA CIENTÍFICA|INVESTIGACIÓN CIENTÍFICA|POLÍTICA UNIVERSITARIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12453,"idioma_id":4,"titulo":"Platy structure development under no-tillage in the northern humid Pampas of Argentina and its impact on runoff","resumen":"...","palabras_clave":"Platy structure |No-tillage|Runoff"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12467,"idioma_id":4,"titulo":"Soil Physical Changes after Conversion of Woodlands to Pastures in Dry Chaco Rangelands (Argentina)","resumen":"The conversion of dry woody rangelands into pastures can alter key soil physical properties that regulate ecosystem water circulation and storage. Based on three paired stands of native woodlands and pastures established 20 years ago in the southern Dry Chaco (San Luis, Argentina), we described contrasts in five soil physical properties using a systematic sampling of soil patches (9-18 patches along a single transect within each of the three paired 1-ha stands). Compared with woodlands, pastures displayed flatter microtopography (mean ± standard deviation [SD]: 3.7 ± 0.34 vs. 5.0 ± 0.67% slope; P < 0.05), lower infiltration rate (mean ± SD: 71.6 ± 9.0 vs. 139.9 ± 37.2 mm h-1; P < 0.05), and higher penetration resistance (mean ± SD: 4.2 ± 0.10 vs. 1.9 ± 0.17 kg cm-2; P < 0.01) and bulk density (mean ± SD: 1.39 ± 0.05 vs. 1.16 ± 0.04 g cm-3; P < 0.0001). On average, topsoil water content at field capacity was similar for both types of cover (mean ± SD: 16.3 ± 0.21 vs. 17.1 ± 1.12%, pastures and woodlands, respectively; P = 0.29). However, at similar bulk density values, pastures presented a &#8764;20% reduction in volumetric water content at field capacity (16.3%) compared with woodlands (19.7%). The establishment of pastures led to more homogenous soils, with most variables having reduced spatial variability in comparison with woodlands. Our observations showed how the conversion of native woodlands to pastures produced strong physical changes in the soils of Dry Chaco and help to understand the mechanisms that are most likely influencing the surface-soil water dynamics of these, and perhaps other, dry rangelands.","palabras_clave":"ARID CHACO|DEFORESTATION|ECOHYDROLOGY|LAND COVER CHANGE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12477,"idioma_id":4,"titulo":"Primary Production of Lowland Natural Grasslands and Upland Sown Pastures Across a Narrow Climatic Gradient","resumen":"Variation in aboveground net primary production (ANPP) is usually studied across wide environmental gradients focusing on spatial averages of zonal natural communities. We studied the spatial and temporal variation of ANPP of upland sown pastures and lowland natural grasslands across a narrow gradient of precipitation and temperature. The Flooding Pampa (Argentina) encompasses an 850?1000 mm range of mean annual precipitation and a 13.8?16.0°C range of mean annual temperature. For 15 100 × 100 km cells, we obtained mean monthly precipitation, temperature, and paddock-level ANPP of upland pastures and lowland grasslands during 8 years. Mean annual ANPP of lowland grasslands and upland sown pastures was positively related to mean annual precipitation. ANPP of upland pastures was 60?80% larger and increased more steeply with mean annual precipitation. ANPP seasonality also changed across the gradient. In lowland grasslands, as mean annual precipitation increased, ANPP monthly maximum increased, minimum decreased, and the duration of the growing season shortened. In contrast, in upland pastures, ANPP monthly maximum was constant, minimum increased, and the growing season lengthened with increasing precipitation. ANPP was more stable across years for lowland grasslands than for upland pastures. The response of annual ANPP to current-year precipitation decreased across the gradient, while the importance of the previous-year precipitation increased. In summary, we found strong spatial and temporal patterns of ANPP across a narrow environmental gradient. In addition, landscape position and species composition heavily influenced those patterns.","palabras_clave":"forage resources|temporal patterns|spatial patterns|seasonality|forage production"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12481,"idioma_id":4,"titulo":"Chironomids as indicators of natural and human impacts in a 700-yr record from the northern Patagonian Andes","resumen":"Chironomid communities were studied in a sediment core collected from Lake Moreno Oeste, located inNahuel Huapi National Park. A major change in midge assemblages occurred at ~AD 1760, which wascharacterized by a decrease of ?cold taxa? including Polypedilum sp.2 and Dicrotendipes, and an increaseof ?warm taxa? including Apsectrotanypus and Polypedilum sp.1. These taxa are likely related to climaticconditions concurrent with the end of a cold period at ~AD 1500e1700 and the beginning of a dryingclimate at ~AD 1740e1900 in northern Patagonia. Coarse tephra layers had low midge diversity; howeverthey did not disrupt the climatic trend as the community recovered rapidly after the event. Since AD1910, after the increase in suburban housing, fish introduction, and the construction of a road, there wasan increase in the relative abundances of taxa typically associated with the littoral zone, such as Parapsectrocladius,Riethia, Apsectrotanypus, and some Tanytarsini morphotypes. The main change in thechironomid community appears to be associated with long-term climate change. At the beginning of the20th century, other site-specific environmental factors (catchment change and fish introduction) alteredthe chironomid assemblages, making it more difficult to understand the relative importance of eachdriver of assemblage change.","palabras_clave":"CHIRONOMIDAE|BIOINDICATORS|PALEOLIMNOLOGY|ENVIRONMENTAL IMPACTS|NORTHERN PATAGONIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12483,"idioma_id":4,"titulo":"Conciliating artisanal and recreational fisheries in Anegada Bay, Argentina","resumen":"tRecreational and artisanal fisheries are common activities in Latin America often interpreted as com-petitors due to the use of common-pool resources in coastal areas. Conflicts between the (historical)artisanal fisheries (AF) and recreational fisheries (RF) in Anegada Bay resulted in the prohibition of theformer. This study addresses key fisheries characteristics to detect the degree of spatio-temporal overlapbetween them considering the annual dynamic of the coastal fish assemblage and proposed manage-ment alternatives. Both fisheries exerted different fishing effort coinciding with the dynamic of the fishassemblages but partial temporal and spatial overlap where apparent especially during one month. How-ever, both fisheries focused their catches on different target species thus greatly reducing the overlapin resource use. Moreover, the low proportion of juveniles caught, limited fishing effort using selectivebottom gillnets and scarce total harvest (168 tonnes\/years) for AF compared with those of RF harvest (631tonnes\/years) in Anegada Bay poorly justifies the actual prohibition. However, the vulnerability index ofAF landings resulted in higher values than the RF. To resolve conflicts, a co-management including AF, RFand industrial (trawl) stakeholders and non-fishing community is suggested. Because of the economicimportance of fishing for local people, an efficient inter and intra-sector communications process andnew fisheries guidelines are urgent for the equitable use of fisheries resources without compromisingthe goals of a protected area.","palabras_clave":"coastal fisheries|Anegada Bay|fisheries conflicts|sea management"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12521,"idioma_id":4,"titulo":"Recycled aggregate concrete: Localized failure assessment in thermodynamically consistent non-local plasticity framework","resumen":"A gradient plasticity theory is extended to predict the mechanical failure behavior of concrete with recycled aggregates. A relevant feature of the novel constitutive formulation is its full consistency with the thermodynamic laws regarding hardening and softening response behaviors. The proposed model includes a formulation of a maximum strength surface which is dependent on the recycled aggregate content. While the hardening law is formulated in the framework of classical-local elastoplasticity, the postpeak behavior is described by means of a non-local gradient and fracture-energy-based law. Thereby, the gradient and fracture-energy characteristic lengths are described in terms of the acting confining pressure and the recycled aggregate content. The formulation of the proposed constitutive theory is complemented by the description of the associated localization indicator, based on the acoustic or localization tensor. Finally, numerical results are presented to demonstrate the predictive capabilities of the proposed model and the performance of the localization indicator for different critical stresses and recycled aggregate contents.","palabras_clave":"GRADIENT PLASTICITY|THERMODYNAMIC CONSISTENCY|RECYCLED AGGREGATE CONCRETE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12522,"idioma_id":4,"titulo":"A Biofilm Model of Microbial Fuel Cells for Engineering Applications. DOI :10.1007\/s40095-017-0249-1-MP-","resumen":"A generalized low-order model of the biofilm in a microbial fuel cell (MFC), suitable foruse in real-time engineering applications, is presented. It is basedon the description of the charge transfer, diffusion process, and charge accumulation inthe biofilm. Since the dynamic processes in an MFC are ruled mainly by thebiofilm, it can be used for many different diffusion-based MFC types by just changingthe boundary conditions. Different mode operations like batch, fed-batch, continuous,etc. are also possible. The time-responses of voltage, substrate concentration on thesurface of the electrode, and Faradaic and capacitive currents have been tested underseveral experimental conditions.","palabras_clave":"Bio&#64257;lm,|Microbial Fuel Cell,|Charge transfer, |Double layer.|Substrate di&#64256;fusion,"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12526,"idioma_id":4,"titulo":"The IRAS 08589-4714 star-forming region","resumen":"We present an analysis of the IRAS 08589-4714 star-forming region. This region harbors candidate young stellar objects identified in the WISE and Herschel images using color index criteria and spectral energy distributions (SEDs). The SEDs of some of the infrared sources and the 70 microns radial intensity profile of the brightest source (IRS 1) are modeled from Herschel fluxes using the one-dimensional radiative transfer DUSTY code. For these objects, we estimate the envelope masses, sizes, densities, and luminosities which suggest that they are very young, massive and luminous objects at early stages of the formation process. Color-color diagrams in the bands of WISE and 2MASS are used to identify potential young objects in the region. Those identified in the bands of WISE would be contaminated by the emission of PAHs. We use the emission distribution in the infrared at 70 and 160 microns, to estimate the dust temperature gradient. This suggests that the nearby massive star-forming region RCW 38, located ~ 10 pc of the IRAS source position may be contributing to the photodissociation of the molecular gas and to the heating of the interstellar dust in the environs of the IRAS source.","palabras_clave":"Regiones HII|Infrarrojo"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12576,"idioma_id":5,"titulo":"Convencionalismo semántico e interpretación jurídica","resumen":"[Artículo en revista indexada en SCOPUS Q4, nivel I de la categorización de publicaciones periódicas de ciencias sociales y humanidades del CONICET]. El presente artículo se caracteriza por tres objetivos específicos. En primer lugar, se reconstruirán las principales versiones del convencionalismo semántico aplicado a la interpretación jurídica que se discuten contemporáneamente en el ámbito angloparlante. Tal convencionalismo supone una identificación entre uso lingüístico compartido y el significado de los enunciados jurídicos. Sin embargo, esa identificación no opera de un modo homogéneo y, por lo mismo, resulta conveniente distinguir entre diversos grados de conexión entre uso lingüístico compartido y significado de los enunciados jurídicos. En segundo término, se presentarán dos dificultades que caracterizan al convencionalismo semántico en el marco de la interpretación jurídica: a) la imposibilidad de evitar un regreso al infinito de interpretaciones; b) la inevitable confusión entre arbitrariedad y discrecionalidad judicial. Finalmente, en la tercera sección de este trabajo se brindará una respuesta a las dificultades del convencionalismo semántico sobre la base de las «nuevas teorías de la referencia» que proponen asignar una prioridad a la referencia o extensión de los conceptos por sobre el significado socialmente construido. (Link SCIMAGO de la revista: https:\/\/www.scimagojr.com\/journalsearch.php?q=21100777217&tip=sid&clean=0)","palabras_clave":"Semántica|Convencionalismo Semántico|Interpretación Jurídica|Arbitrariedad|Discrecionalidad Judicial|Nuevas teorías de la referencia"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12582,"idioma_id":4,"titulo":"SENSORY ACCEPTABILITY OF SQUID RINGS GAMMA IRRADIATED FOR SHELF-LIFE EXTENSION","resumen":"The feasibility of extending the shelf-life of a squid product by gamma irradiation was analyzed. Illex argentinus rings were irradiated at 4 and 8 kGy; and stored at 4±1 °C during 77 days. No mesophilic bacteria, enterobacteriaceae and coliforms were detected in irradiated rings during storage. Psychrotrophic bacteria were significantly reduced by irradiation; their counts were fitted to a growth model which was further used for shelf-life estimations: 3 and 27 days for 0 and 4 kGy, respectively. Initially, non-irradiated as well as irradiated rings had very good sensory scores. The overall acceptability of 4 and 8 kGy rings did not decrease during 27 and 64 days, respectively, while control samples spoiled after 3 days. A radiation dose range for squid rings preservation was defined, which attained the technological shelf-life extension objective, without impairing sensory quality.","palabras_clave":"RADIATION PROCESSING|PRESERVATION|SQUID|SENSORY ACCEPTABILITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12620,"idioma_id":5,"titulo":"El método del discurso y sus relaciones epistemológicas. Apuntes desde la obra de Michel Foucault","resumen":"El artículo desarrolla aspectos teóricos y conceptualizaciones que procuran ser funcionales para analizar, problematizar, interpretar y argumentar lógicamente el trabajo de investigación en el campo de las ciencias sociales y humanas. Se desarrolla un método de análisis del discurso a partir de un punto de vista epistemológico que resulta clave en las nociones de autor, discurso, enunciado, saber, etc.","palabras_clave":"Método|Arqueología|Genealogía|Foucault"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12622,"idioma_id":4,"titulo":"Quality of life and commuting. A study in rururban communities of General Pueyrredon district, Argentine","resumen":"AbstractSearch for quality of life of the population becomes one of the explanatory causes of residential mobility.  Residents move within the territory, use it, make it dynamic and, at the same time, it offers them possibilities or difficulties. In this sense, the processes of urban growth, which spread population centers around road networks, encourage the intensification of everyday commuting and the demands for new services, among which the public passenger transport system and the educational and health infrastructure are leaders (health centers, sewer, main water supply). Currently, in General Pueyrredon County (620,000 inhabitants, 2010) (Buenos Aires, Argentina), commuting becomes visible due to the expansion of the urban conglomerate headed by Mar del Plata and the growth of small towns, close to the access routes to the main town, where the population forms communities that are distinguished by their strong interpersonal links, meanings, values and shared interests. The study area comprehends the whole of the district, but underlines localities having less than 10,000 inhabitants, as it is the area which, over the last three decades, has shown greater demographic and housing growth rate. Accordingly, our aim is to increase people?s awareness over uneven regular movements of inhabitants of rural-urban communities of General Pueyrredon County, taking into account the design of the public transport network, the location of schools and health centers, with the aim of deepening the analysis of the well-being conditions of the people residing there.   Methodologically, we use systematized and analyzed data of the national censuses of 1991, 2001 and 2010, attained by the National Institute of Statistics and Censuses (INDEC), with the purpose of studying demographic growth and the composition of households. We also exploit secondary data that allow characterizing public educational and health services in the studied communities. Similarly, we utilize primary data of commuting and geographic narratives linked to living in minor localities within General Pueyrredon County, evaluated as significant testimonies that allow interpreting and understanding the dynamics observed in the territory. We apply quantitative as well as qualitative analysis techniques, and a system of geographic information for the treatment of georeferenced data.Results will illustrate the inequality of opportunities in commuting and the generation and consolidation of situations of vulnerability in the analyzed communities, in relation to their quality of life.Key words: quality of life, community, commuting, inequality, southeast of Buenos Aires.","palabras_clave":"quality of life|community|commuting|southeast of Buenos Aires.|inequality"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12648,"idioma_id":5,"titulo":"Perfil de ácidos grasos en leche de búfalas alimentadas con pastura natural  y suplementadas con una mezcla de aceites de girasol y pescado","resumen":"El objetivo del estudio fueevaluar el perfil de ácidos grasos (AG) y la calidad nutricional de la leche de búfalas suplementadascon aceites de girasol y pescado. Ocho búfalas de raza Mediterránea fueron suplementadascon 300 ml\/día de una mezcla de aceites de girasol y pescado (210 y 90 ml, respectivamente),durante 60 días. Se tomaron muestras de leche los días 0, 24 y 60 y se analizó elperfil de AG mediante cromatografía gaseosa. La suplementación durante 24 días indujo unsignificativo aumento de las concentraciones de ácidos ruménico, vaccénico y &#945;-linolénicoen 398, 420 y 29%, respectivamente. Las concentraciones de ácidos grasos saturados (AGS)se redujeron 26%; la reducción de los ácidos láurico, mirístico, palmítico y esteárico fue del45, 49, 22 y 33%, respectivamente. La suplementación lipídica de 60 días redujo de manerasignificativa (p=0,0089) las concentraciones de ácido ruménico, cuando se comparó con eldía 24. En cuanto a los índices de calidad de la grasa, la suplementación con aceites durante24 días redujo los índices basales de aterogenicidad (IA) y trombogenicidad (IT) (p&lt;0,0001),aumentó la relación basal de AG hipo\/hipercolesterolémicos (h\/H) (p=0,0008) y no modificóla relación &#969;6\/&#969;3 (p=0,2443). Luego de 60 días de suplementación IA, IT y Rh\/H aumentaronde manera significativa (p=0,0159, 0,0016 y 0,0301 respectivamente) cuando se compararoncon el día 24. Se concluye que la suplementación ensayada produjo una leche con unperfil de AG más adecuada para el consumo humano, con menor contenido de AGS y tenoreselevados de ácidos grasos insaturados (vaccénico, rumémico y &#945;-linolénico). Los cambiosdel perfil de AG fueron acompañados con IA e IT reducidos, e incremento en la relación h\/H.Sin embargo, los altos niveles de ácido ruménico y vaccénico declinaron con la suplementaciónprolongada, al mismo tiempo que aumentaron IA e IT.","palabras_clave":"Acidos grasos |Aceite de girasol y pescado|Leche de bufalas|Salud humana"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12689,"idioma_id":4,"titulo":"Effect of different treatments on the microestructure and functional and pasting properties of pigeon pea (Cajanus cajan L.), dolichos bean (Dolichos lablab L.) and jack bean (Canavalia ensiformis) flours from the north-east Argentina.","resumen":"The effect of germination (G; 5 days), soaking-cooking (SC; 6 h?20 min, 6 h?40 min, 6 h?60 min) and microwave (M; 50%, 70%, 100%) treatments on pigeon pea (PP), dolichos bean (DB) and jack bean (JB) seeds was studied. Microstructure of seeds and functional (protein solubility, water-holding capacity, oil-holding capacity, emulsion stability) and pasting properties of flours were determined. Germination and microwave treatments modified the protein matrix of cotyledon cells preserving the shape of the starch granule, whereas the SC treatment (6 h?60 min) affected both. The soaking-cooking is the most influential treatment on the functional properties of PP, DB and JB flours, as increased water absorption capacity (73?96%), decreased protein solubility (>80%) and the tendency to retrogradation of amylose (69?85%) also improved emulsion stability.","palabras_clave":"MICROSTRUCTURE|PROTEIN SOLUBILITY|EMULSION STABILITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12693,"idioma_id":4,"titulo":"Versatile Fe-Containing Hydroxyapatite Nanomaterials as Efficient Substrates for Lead Ions Adsorption","resumen":"The capability of paramegnetic iron-containing hydroxyapatite (Fe-nAp) and waste bioorganic subtrates templeted iron-containing hydroxyapatite (SBO-Fe-nAp) nanoparticles, as Pb(II) cations adsorbants were investigated and compared to those of synthetic hydroxyapatite (nAp). Surface and bulk characterization techniques as XPS, XRD, electrophoretic mobility, FTIR spectroscopy, DLS, and TEM were used to investigate the adsorption mechanisms involved and ICP-AES to determine Pb(II) concentrations in aqueous solutions. The apatite-based nanoparticles were found to be efficient materials for the irreversible adsorption of Pb(II) ions from aqueous solutions, with maximum adsorption capacity increasing as: hydroxyapatite < waste bioorganic subtrates templeted ironcontaining hydroxyapatite < iron-containing hydroxyapatite. Adsorption capacities of 1500 mg g-1 observed for iron-containing hydroxyapatite, are among the highest reported for Pb(II) adsorption. The high surface to volume ratio, low crystallinity, and the negatively charged surface, strongly favour aqueous Pb(II) adsorption on Fe-containing apatites over the positively charged crystalline hydroxyapatite. The adsorption mechanisms involved depend on the available surface hydroxyl and carboxyl groups as well as on the formation of stable lead-containing hydroxyapatite-like structures. Moreover, bimetal adsorption experiments involving Cu(II) and Pb(II) ions show particular selectivity depending on the surface chemistry of the hydroxyapatite-based adsorbent. While hydroxyapatite is selective towards Pb(II), Fe-containing hydroxyapatite selectivity depends on the relative [Pb]\/[Cu] ratio, and waste bioorganic subtrates templeted Fe-containing hydroxyapatite, adsorbs both ions with similar capability.","palabras_clave":"Paramagnetic Nanoparticles|Pb(II) Adorption|Cu(II) Adsorption|Bio-Organic Substrates|Surface Chemistry"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12721,"idioma_id":4,"titulo":"How does a viviparous semifossorial lizard reproduce? Ophiodes intermedius (Squamata: Anguidae) from subtropical climate in the Wet Chaco region of Argentina","resumen":"The best predictors of reproductive patterns are commonly associated with climate factors, but evolutionary history also plays an important role. The semifossorial and viviparous lizard Ophiodes intermedius from the Wet Chaco region of Argentina showed an annual cycle with asynchrony between males and females and an unusual pattern for subtropical climates, with vitellogenesis beginning in autumn, ovulation and copulation in spring, and births occurring in summer. Males exhibited annual variation of testicular size associated with spermatogenic activity, reaching their maximum gonadal activity in late summer (March), but sperm storage in the epididymis and\/or deferent duct occurred throughout the year. Females showed an extended reproductive cycle beginning in mid-autumn (May) with vitellogenesis and finishing with births from late spring to mid-summer (December to February). Litter size varied from 4 to 9 offspring. Females reached sexual maturity at a larger snout?vent length and, overall, showed greater body size than males, while males exhibited larger heads than females. Fat body cycles indicated that females use lipid reserves to support vitellogenesis and embryo development, while males allocate lipid resources to the search for females, courtship and copulation rather than to gametogenesis. Ophiodes intermedius differed from other species of the genus in litter size, gestation period, timing of birth and the minimum size at sexual maturity, probably as a result of the influence of ecological, historical and phylogenetic factors.","palabras_clave":"Reproductive cycle|Spermatogenesis|Vitelogenesis"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12722,"idioma_id":4,"titulo":"The Phosphatidylinositol 3-kinase Class III Complex Containing TcVps15 and TcVps34 Participates in Autophagy in Trypanosoma cruzi","resumen":"Autophagy is a degradative process by which eukaryotic cells digest their own components to provide aminoacids that may function as energy source under nutritional stress conditions. There is experimental evidence for autophagy in parasitic protists belonging to the family Trypanosomatidae. However, few proteins implicated in this process have been characterized so far in these parasites. Moreover, it has been shown that autophagy is involved in Trypanosoma cruzi differentiation and thus might have a role in pathogenicity. Here, we report the cloning and biochemical characterization of TcVps15. In addition, we demonstrate that TcVps15 interact with the PI3K TcVps34 and that both proteins associate with cellular membranes. Under nutritional stress conditions, TcVps15 and TcVps34 modify their subcellular distribution showing a partial co-localization in autophagosomes with TcAtg8.1 and using an active site TcVps15-mutated version (TcVps15-K219D-HA) we demonstrated that this relocalization depends on the TcVps15 catalytic activity. Overexpression of TcVps15-HA and TcVps15-K219D-HA also leads to increased accumulation of monodansylcadaverine (MDC) in autophagic vacuoles under nutritional stress conditions compared to wild-type cells. In addition, the MDC-specific activity shows to be significantly higher in TcVps15-HA overexpressing cells when compared with TcVps15-K219D-HA. Our results reveal for the first time a role of TcVps15 as a key regulator of TcVps34 enzymatic activity and implicate the TcVps15-Vps34 complex in autophagy in T. cruzi, exposing a new key pathway to explore novel chemotherapeutic targets.","palabras_clave":"Autophagy|Trypanosoma cruzi|vesicular acidification|Vps15"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12726,"idioma_id":4,"titulo":"Interactive and non interactive multi-trap models in thermoluminescence: Closed expressions derived without approximations for analyzing glow curves","resumen":"The kinetics usually employed for analyzing glow curves are either heuristic or derived from physical models resorting to approximations. In this article closed expressions for the interactive and non interactive multi-trap models are derived without approximations, which render the analysis of glow curves more reliable.","palabras_clave":"THERMOLUMINESCENCE|GLOW CURVE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12728,"idioma_id":4,"titulo":"Deforestation impacts on soil organic carbon stocks in the Semiarid Chaco Region, Argentina","resumen":"Land use change affects soil organic carbon (SOC) and generates CO2 emissions. Moreover, SOC depletion entails degradation of soil functions that support ecosystem services. Large areas covered by dry forests have been cleared in the Semiarid Chaco Region of Argentina for cropping expansion. However, deforestation impacts on the SOC stock and its distribution in the soil profile have been scarcely reported. We assessed these impacts based on the analysis of field data along a time-since-deforestation-for-cropping chronosequence, and remote sensing indices. Soil organic C was determined up to 100 cm depth and physically fractionated into mineral associated organic carbon (MAOC) and particulate organic C (POC). Models describing vertical distribution of SOC were fitted. Total SOC, POC and MAOC stocks decreased markedly with increasing cropping age. Particulate organic C was the most sensitive fraction to cultivation. After 10 yr of cropping SOC loss was around 30%, with greater POC loss (near 60%) and smaller MAOC loss (near 15%), at 0?30 cm depth. Similar relative SOC losses were observed in deeper soil layers (30?60 and 60?100 cm). Deforestation and subsequent cropping also modified SOC vertical distribution. Soil organic C loss was negatively associated with the proportion of maize in the rotation and total crop biomass inputs, but positively associated with the proportion of soybean in the rotation. Without effective land use polices, deforestation and agricultural expansion can lead to rapid soil degradation and reductions in the provision of important ecosystem services.","palabras_clave":"DEGRADATION|SOC|C STOCK"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12772,"idioma_id":5,"titulo":"Recepción del Contrato de Cajas de Seguridad en el Código Civil y Comercial","resumen":"El Código Civil y Comercial  aprobado por  Ley 26.994 que entró en vigencia el 1 de Agosto de 2015  regula en general, lo relativo a los derechos de las personas con discapacidad en su  Libro Primero-Parte General, Sección 3,  bajo el título: Restricciones a la capacidad, existiendo además otras normas sobre cuestiones especificas  referidas a derechos de  las personas con discapacidad en otras partes del  C.C.y C. como por ejemplo en sucesiones, responsabilidad civil, etc. Así, el código introduce cambios importantes en la temática   armonizando así la legislación interna  a los principios impuestos por la Convención sobre Derechos de las Personas con Discapacidad (2006) que fue incorporada a nuestro sistema jurídico por ley 26.378 (2008) y a partir del año 2014 por  ley 27.044 se le  otorgó jerarquía constitucional en los términos del art. 75 inc. 22 CN. El nuevo ordenamiento jurídico recepta el modelo social de la discapacidad dejando de lado el modelo medico-rehabilitador que contemplaba el Código Civil de Vélez, guardando coherencia también con la Ley 26.657 de Salud Mental (2010), que incorpora en nuestro derecho interno los postulados y principios de la Convención sobre los Derechos de las Personas con Discapacidad.","palabras_clave":"DERECHO CONTRACTUAL|CAJAS DE SEGURIDAD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12775,"idioma_id":5,"titulo":"Territorios ajenos.El caso de la Cooperativa Agropecuaria de Presidencia Roque Sáenz Peña Ltda, Chaco.","resumen":"El artículo se propone describir y analizar las estrategias (socio-productivas) de la Cooperativa Agropecuaria de Presidencia Roque Sáenz Peña Ltda. (CARSP) a partir de sus acciones y representaciones ante las transformaciones socio-productivas agrarias acontecidas con el agronegocio en la provincia de Chaco. En una primera sección, se presenta la perspectiva teórica acerca del territorio, las organizaciones y el discurso que se aplica. En una segunda sección, se avanza en una breve historia de lo acontecido en el territorio chaqueño a partir del agronegocio y articula el recorrido regional con el reconocimiento de lo sucedido al conjunto del sector cooperativo agrario. En la tercera sección, se presenta y analiza el discurso del caso cooperativo frente a los cambios territoriales y sus estrategias.","palabras_clave":"COOPERATIVAS AGRARIAS|CHACO|AGRONEGOCIO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12822,"idioma_id":5,"titulo":"La intervención estatal en el mundo del trabajo: la aplicación de la Ley de Descanso Dominical en el centro bonaerense (Tandil, 1917-1930)","resumen":"El objetivo de este trabajo es analizar en el ámbito rural y urbano del centro bonaerense el accionar del Departamento del Trabajo de la Provincia de Buenos Aires (DPT), abordando la aplicación de la Ley de Descanso Dominical. A partir de un estudio de caso, pretendemos observar las relaciones establecidas entre aquella repartición provincial y la sociedad local del partido de Tandil y su zona de influencia. Estudiaremos las formas iniciales a través de las cuales se vincularon los funcionarios provinciales y las problemáticas obreras del interior bonaerense, y las reacciones causadas por la intervención de los funcionarios del DPT.","palabras_clave":"Legislación laboral|Departamento del Trabajo de la provincia|Trabajo rural y trabajo urbano|Centro bonaerense"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12827,"idioma_id":5,"titulo":"¿En primera plana? El abuso sexual de menores y los cambios de la Iglesia Católica","resumen":"No obstante la complejidad del asunto, que amerita un tratamiento interdisciplinar exhaustivo, y la creciente bibliografía alusiva en las diferentes áreas lingüísticas, la presente comunicación se concentra en los principales núcleos teológico-pastorales de algunas de las últimas declaraciones públicas de la Iglesia católica en relación a esta problemática, tanto del Papa Francisco (1) como del nuevo organismo creado en la Curia Romana, una ayuda institucional al ministerio petrino (2). A continuación, se ofrece un breve panorama de la propuesta de la Conferencia Episcopal Argentina, correspondiente a una solicitud planteada a todas las Conferencias Episcopales del mundo (3). En las reflexiones finales, se ofrece un primer balance crítico y se plantean interrogantes (4). La comunicación intenta, pues, contribuir a este aspecto medular de la conversión pastoral de la Iglesia católica, ya en curso.","palabras_clave":"PEDERASTIA|PEDOFILIA|CONVERSION PASTORAL|AUTORIDAD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12835,"idioma_id":4,"titulo":"Anti-neuroblastoma properties of a recombinant sunflower lectin","resumen":"According to their sugar recognition specificity, plant lectins are proposed as bioactive proteins with potential in cancer treatment and diagnosis. Helja is a mannose-specific jacalin-like lectin from sunflower which was shown to inhibit the growth of certain fungi. Here, we report its recombinant expression in a prokaryotic system and its activity in neurobalstoma cells. Helja coding sequence was fused to the pET-32 EK\/LIC, the enterokinase\/Ligation-independent cloning vector and a 35 kDa protein was obtained in Escherichia coli representing Helja coupled to thioredoxin (Trx). The identity of this protein was verified using anti-Helja antibodies. This chimera, named Trx-rHelja, was enriched in the soluble bacterial extracts and was purified using Ni+2-Sepharose and D-mannose-agarose chromatography. Trx-rHelja and the enterokinase-released recombinant Helja (rHelja) both displayed toxicity on human SH-SY5Y neuroblastomas. rHelja decreased the viability of these tumor cells by 75% according to the tetrazolium reduction assay, and microscopic analyses revealed that the cell morphology was disturbed. Thus, the stellate cells of the monolayer became spheroids and were isolated. Our results indicate that rHelja is a promising tool for the development of diagnostic or therapeutic methods for neuroblastoma cells, the most common solid tumors in childhood.","palabras_clave":"AGGLUTININ|HELIANTHUS ANNUUS|HELJA|JACALIN|NEUROBLASTOMA|RECOMBINANT LECTIN|TUMOR TOXICITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12838,"idioma_id":4,"titulo":"Films made by blending poly(&#949;-caprolactone) with starch and flour from sagu rhizome grown at the Venezuelan Amazons","resumen":"Starch-based composite films have been proposed as food packaging. In this context, the study of non-conventional starch sources (sagu, Canna edulis Kerr) has worldwide special attention, because these materials can impart different properties as carbohydrate polymers. A thorough study of the matrices used (sagu starch and flour) was carried out. In the same way, thermoplastic starch (TPS)\/PCL blend and thermoplastic flour (TFS)\/PCL blend were obtained by melt mixing followed by compression moulding containing glycerol as plasticizer. In this study, chemical composition of the matrices and their properties were related with the properties of the developed films. Moisture content, water solubility, X-ray diffraction, thermogravimetric analysis and mechanical and microstructural properties were evaluated in the films. Taking into account the results, the sagu flour has great potential as starchy source for food packaging applications. However, concretely the flour had lower compatibility with the PCL compared to the starch\/PCL blend.","palabras_clave":"Blends|Films|Poly(&#949;-caprolactone)|Sagu starch and flour"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12841,"idioma_id":4,"titulo":"Effects of native and oxidized corn starch\/polystyrene blends under conditions of reactive extrusion using zinc octanoate","resumen":"Native and oxidized corn (Zea mays) starch\/polystyrene (PS) blends containing glycerol as a plasticizer were prepared by reactive extrusion in a twin-screw extruder using zinc octanoate (Zn(Oct)2) as a catalyst, followed by compression molding. Blends were characterized in terms of their: average molecular weight, moisture content, infrared (FTIR) spectra, water solubility, thermogravimetric (TGA) properties, differential scanning calorimetry (DSC) curves, X-ray diffraction (XDR) patterns, stability in acidic or alkaline medium, and microstructural, mechanical and antimicrobial properties. The results clearly show that the catalyst used produced cross-linking between the starch and PS, and that the oxidative modification of the starch increased its reactivity. This was demonstrated by the increase in molecular weight, thermal resistance, and hydrophobicity of films prepared from the oxidized starch\/PS plus catalyst. This increase in hydrophobicity of the starch modified systems was due to the carboxyl and carbonyl groups introduced into the starch structure. As a result, phase separation was more obvious, despite the increase in the cross-linking rate between the oxidized starch and the PS. Finally, none of the films showed signs of swelling or antimicrobial activity. Nonetheless, the catalyst exhibited excellent antimicrobial activity against the pathogenic microorganisms evaluated.","palabras_clave":"Blends|Corn starch|Oxidized starch|Polystyrene"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12861,"idioma_id":5,"titulo":"Hay una voluntad de plasticidad extraordinaria en mi escritura. Entrevista a Edgardo Rodríguez Juliá","resumen":"Novelista, cronista, ensayista, ningún género parece haber amedrentado la prodigalidad inventiva y la capacidad reflexiva de Rodríguez Juliá. En esta entrevista repasamos algunos de los puntos más sobresalientes de su obra.","palabras_clave":"Novela|Historia|Puerto Rico|Colonialismo"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":12873,"idioma_id":4,"titulo":"Anaerobically Incubated Nitrogen Improved Nitrogen Diagnosis in Corn","resumen":"Current N diagnostic methods for corn (Zea mays L.) are oft en based on the nitrate nitrogen (NO3 &#8722;?N) concentration before planting (pre-plant nitrate test, PPNT) and nitrate nitrogen (NO3 &#8722;?N) concentration at V6 stage (PSNT). These tests provide scant information on soil N mineralization during the growing season, which can supply a considerable proportion of corn N requirements. The objective of our study was to evaluate if in-season N recommendations could be improved by inclusion of a N mineralization potential estimator. We conducted field experiments (n = 35) in three different areas and in two planting dates. At each site we evaluated PPNT, PSNT, and NH4?N released during anaerobic incubation (Nan), which were then related to corn yield in unfertilized plots (0N) and corn response to nitrogen fertilization (Nresp%) using multiple regression analysis. The sole incorporation of Nan to PPNT and PSNT models improved their capacity to predict corn yield in 0N plots and Nresp% only in areas with similar edaphic-climatic characteristics. Independently of the geographical region, when PPNT and PSNT were combined with Nan, texture, and temperature, their capacity to predict yield in 0N plots was increased (PPNT: from R2 0.02?0.47; PSNT: from R2 0.09?0.53), as it was their capacity to estimate Nresp% (PPNT: from R2 0.06?0.23; PSNT: from R2 0.19?0.42). The inclusion of Nan can improve traditional N diagnostic models when it is combined with edaphic\/climatic properties that account for the mineralization rate of this N pool.","palabras_clave":"NITROGEN|MINERALIZATION|CORN|ANAEROBIC INCUBATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13018,"idioma_id":5,"titulo":"La 'transición' argentina como objeto historiográfico y como problema histórico","resumen":"Este artículo analiza el llamado proceso de ´transición a la democracia´ en la Argentina desde la óptica de cómo fue percibido política y socialmente el problema de los crímenes aberrantes cometidos por el régimen dictatorial (1976-1983). Para ello, el trabajo se centra en los dos últimos años de ese régimen y muestra que la llamada ´cultura de los derechos humanos´ y la denuncia de esos crímenes tuvo un alcance más limitado del que se recuerda cuando se explica el gran cambio político y cultural de la transición. Asimismo, también se deje en evidencia que buena parte de los reclamos sobre el tema de parte de los actores de la oposición política estuvo dado por la necesidad de resolver la cuestión y 'cerrar' el pasado para evitar problemas de gobernabilidad política en el nuevo período democrático.","palabras_clave":"Transición|Democracia|Dictadura|Derechos Humanos"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13050,"idioma_id":4,"titulo":"Microscale nest-site selection by the Burrowing Owl in the Pampas of Argentina","resumen":"Habitat modifications have led many bird species to occupy areas with different characteristics, including human-altered landscapes. In this study, we analyzed how land use influences the nest-site selection at the microscale level by Burrowing Owls (Athene cunicularia) breeding in vegetated sand dunes, periurban areas, and agroecosystems in the Pampas of Argentina. We compared the characteristics of the nest site (percentage of open space) and the nest patch (distance to conspecific nests, tall vegetation and perches and number of perches) within and among the three land-cover types. In addition, we evaluated the breeding performance (nesting success and productivity) of owls nesting in these land-cover types. We found that nest microsite variables did not vary between owl-occupied and owl-unoccupied sites within nest patches, but they differed among land-cover types. Although nest patches differed in their availability of perches at each land-cover type, distance from the nest to the nearest perch did not vary between them. Distances to tall vegetation and to conspecific nests were highly variable and did not differ among land-cover types. Our results indicate that Burrowing Owls that inhabit the Pampas used a variety of land-cover types for nesting and showed little selectivity of nest sites and nest patches, thus reinforcing the idea that they are habitat generalists.","palabras_clave":"Athene cunicularia | modified habitat| natural habitat | productivity |nesting success"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13056,"idioma_id":4,"titulo":"Nutrient Partitioning and Stoichiometry in Soybean: A Synthesis-Analysis Field Crops Research","resumen":"On-farm attainable soybean yields are primarily limited by nutrient and water supply. High-yielding soybeans is related to high nutrient uptake. A proposed theoretical framework underpinning yield formation includes plant nitrogen (N) uptake, N harvest index (NHI), and N seed concentration (%Nseeds). The objectives of this study were focused on (i) investigating the effect of NHI and %Nseed on yield-to-uptake relation for N, and (ii) analyzing dry mass and N partitioning and extending this analysis to phosphorous (P) and potassium (K) uptake and (iii) studying the influence of specific seed:stover ratios on the relationship of N with P, and K uptake. Metadata on yield, nutrient uptake and specific-organ nutrient concentration (%nutrient) was summarized from experiments located in three different environments: Indiana, Kansas (both US), and Argentina (herein termed as IN, KS, and ARG, respectively). The main outcomes from this research were: 1) the yield-to-uptake relation for N was primarily explained by NHI; 2) the algebraic model proposed by Sinclair (1998), that includes each specific-organ %nutrient explained consistently nutrient (N, P or K) HI as a function of HI with different trend, and 3) plant nutrient ratios were primarily governed by vegetative %nutrient (stover fraction), acting as a nutrient reservoir or supply depending on the demand of nutrient in the seed. Further research on the nutrient and biomass partitioning should focus on examining the NHI:HI relationship under varying genotype x environment x management interaction","palabras_clave":"soybean|phosphorus|nitrogen|potassium"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13066,"idioma_id":5,"titulo":"Conjuntos cerámicos en contextos de interacción. Análisis diacrónico de la alfarería del sitio Los Viscos (Valle del Bolsón, Belén, Catamarca).","resumen":"Se presentan los resultados de la caracterización estilística y del análisis tecnológico y petrográfico sobre conjuntos cerámicos recuperados en el sitio Los Viscos, valle del Bolsón (Departamento de Belén, Provincia de Catamarca). Se trata un alero que fue reocupado de manera discontinua pero recurrente entre un lapso ca. 1000 AC-1440 DC y fue utilizado como refugio temporal vinculado a actividades de tránsito interregional. Los restos de alfarería que quedaron como resultado de dichas ocupaciones corresponden a los períodos Formativo, Desarrollos Regionales e Hispano Indígena.  Se realiza un análisis sincrónico y diacrónico de los mismos con el propósito de contribuir por un lado, al estudio de las prácticas de producción cerámica en el valle y además, brindar evidencia para vincular al sitio con actividades de interacción con diferentes regiones. De este modo, se problematiza la procedencia de las piezas recuperadas y se sugiere una circulación diferencial entre la cerámica fina y la ordinaria que se reproduce a lo largo de la secuencia.","palabras_clave":"PRODUCCIÓN ALFARERA|CIRCULACIÓN INTERREGIONAL|PETROGRAFÍA|DIACRONÍA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13087,"idioma_id":4,"titulo":"Parental care and external sexual characters in the Warbling Doradito (Pseudocolopteryx flaviventris)","resumen":"Biparental care is the dominant (81 %) form of parental care in birds. The degree of sexual selection and the resulting mating system and parental care type have been determined, in many cases, by inference from external characters of sexual dimorphism. The lack of information and the biological attributes of the tyrant flycatchers (e.g., low sexual dimorphism) make it difficult to determinate the parental care roles in most species. Tyrant flycatchers comprise a diverse bird family, but information on the reproductive behavior of many Tyrannid species is lacking. Our aim was to describe external sexual characters (morphology and coloration) and determine the parental care behavior at the nest in the Warbling Doradito (Pseudocolopteryx flaviventris), especially considering the potential role of sexual differences in relation to parental roles at nest. We studied the parental care behavior during two breeding seasons. Parents were captured to take morphological measurements and a blood sample for molecular sex determination. We found that parental care in the Warbling Doradito was biparental biased toward females, where the incubation was performed exclusively by females and the 74 % of activities of nestling brooding and feeding was performed by females. We also found sexual differences, slight in size and plumage, but more conspicuous in bill color. Despite the relatively slight sexual dichromatism of the Warbling Doradito, the parental care behavior in the nest was biased towards females, and the assistance of males to nestlings was highly variable and was not correlated with either clutch size or increasing nestling mass. Therefore, the evidence presented here suggest that Pseudocolopteryx genus may have an unusual social system, otherwise uncommon in tyrannids.","palabras_clave":"Tyrannidae \u0002 |\u0002 Morphology \u0002 | Nestling feeding \u0002 |Nestling feeding \u0002 Dichromatism \u0002 Argentina|Pampas \u0002 Grasslands \u0002 |Dichromatism \u0002| Argentina"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13104,"idioma_id":5,"titulo":"?Reflexiones acerca de un modelo de evaluación de aprendizajes por criterios a partir del diseño y administración de pruebas de comprensión lectora en el nivel primario argentino.?","resumen":"El presente artículo comparte reflexiones sobre un modelo de evaluación criterial de aprendizajes a partir de una investigación en el área de comprensión lectora en  nivel primario en Argentina. Desde 2003 la Dirección Nacional de Información y Evaluación de la Calidad Educativa en Argentina implementa el Operativo Nacional de Evaluación para estudiar el desempeño de los alumnos en Lengua, Matemática, Ciencias Sociales y Ciencias Naturales, en distintas etapas de su educación. Para analizar y comprender el modelo de evaluación criterial utilizado, dicho proyecto diseñó y administró pruebas de comprensión lectora a 223 alumnos de diez terceros años de siete escuelas primarias locales. Los objetivos fueron indagar sobre posibles formas de describir y evaluar las competencias de los alumnos y ofrecer información al sistema educativo local sobre el desempeño del alumnado. Los resultados indicarían que la población evaluada exhibe dificultades en el manejo de algunos procesos involucrados en la lectura comprensiva.","palabras_clave":"EVALUACIÓN|CRITERIOS|LECTO-COMPRENSIÓN|PRIMARIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13158,"idioma_id":4,"titulo":"EFFECT OF DIFFERENT FIBERS ON DOUGH PROPERTIES AND BISCUIT  QUALITY","resumen":"BACKGROUND: This study forms part of a broader project aimed at understanding the role of fibers from different sources in high-fat, high-sugar biscuits and at selecting the best fibers for biscuit quality. The main purpose of this work was to understand the rheological and structural properties involved in fiber-enriched biscuit dough. High-amylose corn starch (RSII), chemically modified starch (RSIV), oat fiber (OF) and inulin (IN) were used at two different levels of incorporation (6 and 12 g) in dough formulation. The influence of fiber on the properties of biscuit dough was studied via dynamic rheological tests, confocal microscopy and spreading behavior. Biscuit quality was assessed by width\/thickness factor, texture and surface characteristics, total dietary fiber and sensory evaluation. RESULTS: Main results indicated that IN incorporation increased the capacity of dough spreading during baking and thus improved biscuit quality. OF reduced dough spreading during baking and strongly increased its resistance to deformation. RSII and RSIV slightly affected the quality of the biscuits. Sensory evaluation revealed that the panel liked IN-incorporated biscuits as much as control biscuits. CONCLUSION: The increase in total dietary fiber modified dough behavior and biscuit properties, and the extent of these effects depended on the type of fiber incorporated. © 2016 Society of Chemical Industry.","palabras_clave":"dough|dietary fiber|rheology|cookie\/biscuit quality|sensory evaluation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13176,"idioma_id":5,"titulo":"Ni cabalmente clásico, ni completamente molecular. Un análisis del concepto de gen en la genética del comportamiento","resumen":"El modo en que las ciencias biológicas conceptualizan a los genes ha sido analizado por diversos autores de la filosofía de la biología. Pese al reconocimiento de una pluralidad de conceptos de gen diferentes al seno de la disciplina, se ha impuesto una conceptualización de carácter principalmente dualista, identificando un concepto de gen clásico (Gen-P) y otro concepto de gen molecular (Gen-D). A su vez, se ha manifestado la independencia de tales conceptos y la imposibilidad de hallar nociones ?híbridas?. En este trabajo analizamos con cuáles conceptos de gen opera la genética del comportamiento y mostramos que la caracterización hegemónica no se ajusta a lo que sucede en el área. En particular, postulamos que en la genética del comportamiento conviven dos conceptos de gen distintos, siendo uno de ellos de índole ?híbrida?. De aquí que nuestra propuesta se enmarca en el consenso pluralista de la filosofía de la biología pero rechaza el carácter dualista que ha fundamentalmente adoptado.","palabras_clave":"GEN|GENÉTICA DEL COMPORTAMIENTO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13181,"idioma_id":4,"titulo":"Effects of Lactobacillus johnsonii AJ5 metabolites on nutritional\/immunological parameters, Nosema ceranae sporulation and performance of Apis mellifera colonies.","resumen":"ver archivo adjunto","palabras_clave":"APIS MELLIFERA|NUTRITION|LACTOBACILLUS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13202,"idioma_id":4,"titulo":"Temperature extremes in the Argentina central region and their monthly relationship with the mean circulation and ENSO phases","resumen":"The aim of this study is to analyze the interannual variability of monthly climatic indices of extreme daily temperature in the central-north region of Argentina throughout a year and its relationship with the atmospheric circulation. The impact of ENSO over different temperature indices throughout the year is specially analyzed. Globally used indices in the 1970-2010 period are utilized for this purpose. The trends of temperature extremes show warming conditions in several months, especially in October and November. In order to find possible forcings of extreme temperature in the region at monthly scale, the co-variability with other circulation monthly time series such as changes in the intensity of Southern Hemisphere semi-permanent anticyclones and the intensity of the subtropical jet were studied. The main finding was a systematic shift of the South Atlantic anticyclone towards the west over the decades in June and August, which might hinder the cold advections over the region surveyed. Moreover, the influence of the variation on the intensity of the subtropical jet over extreme events showed significant positive (negative) correlations between the intensity of the jet and the frequency of cold (warm) indices in a great number of months. Finally, the influence of the ENSO phases on each of the temperature extremes analyzed was studied. It was found out that under El Niño conditions, minimum temperatures are affected quite evenly throughout the year, fostering the occurrence of warm nights. The impact of the El Niño event on the maximum extreme temperatures, however, shows seasonal differences. Between July and September warm days conditions are fostered, while between November and February the opposite (cold days) can be seen. This results in a decrease in the temperature range in the region surveyed during the summer months under El Niño conditions","palabras_clave":"ENSO|TEMPERATURAS EXTREMAS|ARGENTINA|CIRCULACION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13216,"idioma_id":5,"titulo":". TUC 403 y TUC 464 dos nuevas variedades de garbanzo tipo Kabuli para el noroeste argentino.","resumen":"Desde el punto de vista genético se reconocen dos tipos de garbanzo: el Kabuli y el Desi. En la Argentina solo se siembra el tipo Kabuli y la disponibilidad de variedades no es amplia, siendo Chañaritos S-156, Norteño, Kiara UNCINTA y Felipe UNC- INTA las únicas inscriptas. El aporte de nueva genética será fundamental para el futuro desarrollo del cultivo del garbanzo, no solo por la baja disponibilidad de variedades que existe en el medio sino que, con seguridad, muchas de ellas han perdido parte de su pureza varietal. Por lo tanto, la disponibilidad de una mayor diversidad genética permitirá que el productor cuente con la posibilidad de elegir cultivares adecuados para cada región. El objetivo de este trabajo es presentar a TUC 403 y TUC 464, primeras variedades de garbanzo tipo kabuli inscriptas por la Estación Experimental Agroindustrial Obispo Colombres (EEAOC). Estas fueron seleccionadas a partir del germoplasma introducido desde el International Center for Agricultural Research in the Dry Areas (ICARDA), de Siria, desde el año 2002. Los viveros de líneas elite introducidos a partir de ese año fueron sembrados en parcelas de observación en la localidad de La Ramada (Tucumán, Argentina), donde se evaluaron y seleccionaron por su porte, fenología, adaptación, rendimiento y calidad de grano. De los viveros introducidos en los años 2002, 2003, 2004 y 2006 se destacaron 16 genotipos, los que se evaluaron en un Ensayo Preliminar (EP) en el año 2008 en La Ramada. En los años 2009, 2010, 2011 y 2012, esos genotipos pasaron a integrar los Ensayos Comparativos de Rendimiento (ECR) realizados en dos localidades por año. El testigo local fue el cultivar Norteño. Como resultado se identificaron líneas que fueron inscriptas con el nombre de TUC 403 y TUC 464, cuyas características son las de presentar buen comportamiento agronómico en el noroeste argentino, rendimientos superiores al del testigo, buena calidad de grano y arquitectura de planta adaptada atrilla directa.Palabras clave: garbanzo tipo Kabuli, evaluación y selección, calidad de grano, noroeste argentino.","palabras_clave":"CICER ARIETINUM|DIVERSIDAD GENETICA|ICARDA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13299,"idioma_id":5,"titulo":"El derecho a la ciudad en cuestión: segregación residencial y experiencias de discriminación y circulación de jóvenes en la Ciudad de Córdoba","resumen":"El objetivo de este artículo es analizar la problemática presencia de jóvenes de clases subalternas en las zonas centrales de la ciudad de Córdoba. Para cumplir el objetivo propuesto se utiliza una estrategia metodológica mixta. En la fase cuantitativa se detallan los aspectos estructurales de la segregación de la población en Córdoba mediante técnicas de estadística espacial. En la fase cualitativa se analiza la experiencia de los jóvenes mediante grupos focales seleccionados en base a la vulnerabilidad socioresidencial.&nbsp;El análisis realizado sugiere la interacción de tres procesos que limitan el uso y reproducción del espacio público de la ciudad por los jóvenes de clases subalternas: en primer lugar, procesos de segregación residencial (que consideramos una dimensión objetivo-espacial), en segundo lugar, políticas punitivas desplegadas por el aparato institucional (que consideramos una dimensión objetivo-institucional) y finalmente las experiencias de desplazamiento que tienen los jóvenes de clases subalternas en la ciudad (que consideramos una dimensión subjetiva de las experiencias de circulación en la ciudad).","palabras_clave":"CIUDAD|SEGREGACION|DISCRMIINACION|JOVENES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13342,"idioma_id":5,"titulo":"Percepción y prevención de riesgos ocupacionales en veterinarios rurales","resumen":". Elejercicio de la profesión veterinaria está asociado a numerosos riesgos ocupacionales. Losobjetivos de este trabajo fueron evaluar la percepción de riesgos laborales (PRL), el uso deelementos de protección personal (EPP) y las asociaciones entre sí y con variables sociodemográficasen veterinarios rurales de la Provincia de Santa Fe (Argentina). Se desarrollóun estudio transversal encuestando a 562 veterinarios. Aunque las PRL tendieron a estarcorrelacionadas entre sí, los coeficientes fueron relativamente bajos. Los guantes fueron losEPP más utilizados, pero la frecuencia de uso de otros elementos y la utilización de más deun EPP para una misma actividad fueron bajas. El uso de EPP fue independiente de la PRL.Tanto PRL como uso de EPP estuvieron asociados al sexo y la edad de los encuestados. Lafalta de uso de distintos EPP en forma conjunta indica una real inconsistencia en el comportamientoprofesional de autoprotección.","palabras_clave":"Veterinarios|Riesgos laborales|Percepción de riesgos|Elementos de protección personal"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13379,"idioma_id":4,"titulo":"Comparing strategies for lipid lowering in Argentina: an analysis from the CVD Policy Model ? Argentina","resumen":"Introduction: In Argentina, the national guidelines for lipid control emphasize the use of relatively inexpensive low- or moderate-potency statins by patients at high risk (>20 %) of a cardiovascular event. The objective of this study was to compare the impact and costs of the current national CVD prevention guidelines with regard to morbidity and mortality in Argentina with the impact and costs of three strategies that incorporate high-potency statins. Methods: We used the CVD Policy Model?Argentina to model the proposed interventions. This model is a national-scale, state-transition (Markov) computer simulation model of the CVD incidence, prevalence, mortality, and costs in adults 35?84 years of age. We modeled three scenarios: scenario 1 lowers the risk threshold for treatment to >10 % according the Framingham Risk Score (FRS); scenario 2 intensifies statin potency under current treatment thresholds; and scenario 3 combines both scenarios by lowering the treatment threshold to &#8805;10 % FRS and intensifying statin potency. Results: Scenario 1 would translate into 1400 fewer MIs and 500 fewer CHD deaths every year, a 3 % and 2 % reduction, respectively. Scenario 2 would lead to 2000 fewer MIs and 1000 fewer CHD deaths every year. Scenario 3 would result in the greatest reduction in MIs and CHD deaths, with 3400 fewer MIs and 1400 fewer CHD deaths every year, which translates to a 7 % and 6 % reduction, respectively. All scenarios were cost-effective if the cost of a high-potency statin pill was under US$0.25. Conclusion: Incorporating those individuals with greater than 10 % cardiovascular risk and the use of high-potency statins into Argentina?s national lipid guidelines could result in fewer CHD deaths and events at a reasonable cost.","palabras_clave":"estatinas|cardiovascular"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13391,"idioma_id":4,"titulo":"Descartes' Rule of Signs for Polynomial Systems Supported on Circuits","resumen":"We give a multivariate version of Descartes´ rule of signs to bound the number of positive real roots of a system of polynomial                     equations in n variables with n+2 monomials, in terms of the sign variation of a sequence associated both to the exponent vectors and the given coefficients.                     We show that our bound is sharp and is related to the signature of the circuit.                  ","palabras_clave":"Descartes' rule of signs|multivariate polynomial|real roots|sign variation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13431,"idioma_id":4,"titulo":"Characterization of a unique copper resistance gene cluster in Xanthomonas campestris pv. campestris isolated in Trinidad, West Indies","resumen":"Whole genome sequencing of a copper resistant(CuR) black rot strain of Xanthomonas campestris pv.campestris (Xcc) isolated from a broccoli plant inTrinidad revealed a unique operon for copper resistance.The cop genes of strain Xcc-BrA1 were determined to bepresent on a 160 to 180 kb plasmid shown to be nonconjugativewith other xanthomonads. While nucleotide comparison of a putative 8.0 Kbp copLABMGF genecluster identified in Xcc-BrA1 genome did not revealany homologous region with other known CuRXanthomonas strains fromdiverse origins, the comparisonof the translated amino acid sequence indicated similaritywith X. citri, X. c. pv. citrumelonis and X. vesicatoria Copproteins. Cloning of the copLAB gene cluster from Xcc-BrA1 conferred copper resistance to other coppersensitivexanthomonads. Although Xcc-BrA1 harborscopLAB genes with similar sizes and organization and isable to grow on Cu-amended medium as other CuRxanthomonads, the phylogenetic analysis of nucleotidesequences indicates that the cop cluster in Xcc-BrA1 isunique and distantly related to other copLAB genes fromXanthomonas and Stenotrophomonas. The origin of copperresistance genes in Xcc-BrA1 is likely a result ofhorizontal gene acquisition from a still unknown phylloplanecohabitant. The findings of this study have implicationsfor the management of crop diseases caused by CuRxanthomonads. Future studies could focus on and determiningthe distribution, overall importance and appropriatecontrol measures for strains harbouring these uniquegenes.","palabras_clave":"Xanthomonas|Plasmid|Acridine orange|Crucifers"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13435,"idioma_id":4,"titulo":"The route of administration drastically affect ivermectin efficacy against small strongyles (Cyathastominae) in horses","resumen":"The goal of the current study was to evaluate the comparative efficacy of ivermectin (IVM) againstsmall strongyles (cyathostomins) following its oral and intramuscular (IM) administration, in naturallyparasitized horses. The parasitological data were complemented with the assessment of the plasma dispositionkinetics of IVM. The trial included two different experiments. In experiment I, 40 horses naturallyinfected with small strongyles were randomly allocated into four experimental groups (n = 10) and treatedwith IVM (0.2 mg\/kg) as follows: IVM oral paste, animals were orally treated with Eqvalan® (IVM 1.87%paste, as the reference formulation) by the oral route; IVM oral solution, animals were orally treated withRemonta® (IVM 2% solution, as a test formulation); IVM IM solution, animals were IM treated with thetest product (Remonta® IVM 2% solution); and control, animals were kept without treatment as untreatedcontrols. In experiment II, 24 horses naturally parasitized with small strongyles were randomly allocatedinto the same four experimental groups (n = 6) described for experiment I. Faecal samples were individuallycollected directly from the rectum of each horse prior (day&#8722;1) and at 7 and 15 (ExperimentI) or 7, 15 and 21 (Experiment II) days after-treatment, to assess the eggs per gram (epg) counts andestimate the efficacy of the treatments. Additionally, the comparative plasma disposition kinetics of IVMin treated animals was assessed in experiment II. In both experiments, an excellent (100%) IVM efficacywas observed after its oral administration (test and reference formulations). However, the IM administrationof IVM resulted in a low efficacy (36?64%). Similar IVM plasma concentration was observed afterits oral administration as a paste or as a solution. The higher IVM plasma profiles observed after the IMadministration accounted for an enhanced systemic availability. The improved IVM efficacy observedagainst adult cyathostomins after its oral administration can be explained by an enhanced drug exposureof the worms located at the lumen of the large intestine. These findings may have a direct impact on thepractical use of macrocyclic lactones in horses.","palabras_clave":"IVERMECTIN|EFFICACY|SMALL STRONGYLES |PHARMACOKINETICS|HORSES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13486,"idioma_id":5,"titulo":"DIFUSIVIDAD DEL AGUA EN EL SUELO: UN MÉTODO SIMPLE DE LABORATORIO PARA SU DETERMINACIÓN","resumen":"La determinación de la Difusividad (D) del agua en el suelo es importante ya que caracteriza el flujo de agua en condiciones no saturadas. Estimarla es complejo, ya que consume tiempo y generalmente se necesita equipo costoso para hacerlo. Los objetivos de este trabajo fueron: 1- proponer una mejora en el método de Whisler et al. (1968) haciéndolo más simple y robusto, aportando herramientas para probar la validez de la ecuación de Richards en su forma de difusividad y el cumplimiento de los supuestos del modelo y 2- Determinar la D en función del contenido de humedad (&#952;) y S en un suelo bajo distintas situaciones productivas. Para esto, se tomaron muestras del horizonte superficial de tres lotes contiguos bajo distintos sistemas de manejo (T1: Pastizal natural, T2: Pastura polifítica y T3: Siembra Directa). Las muestras se secaron, tamizaron por 2 mm y se empaquetaron en columnas de PVC de 70 cm de largo y 10 cm de diámetro interno. Las columnas de suelo se sometieron a infiltración horizontal y se determinó la D a distintos valores de &#952; y la S. Se utilizaron sensores de humedad de capacitancia de bajo costo en puntos fijos de la columna. Los resultados encontrados muestran la validez de la metodología para los suelos estudiados. En cuento a la influencia del manejo, se encontraron diferencias significativas en los valores de D entre los tratamientos. El T3 presentó mayores valores de D a todas las humedades, y de S, que T1 y T2 (los valores de D estuvieron entre 0,00033 y 0,0321 cm2.s-1), lo que indica mayor facilidad para transmitir agua en condiciones no saturadas en el manejo agrícola, lo cual se atribuyó a la influencia negativa del pisoteo animal. La metodología propuesta permitió estimar de manera consistente, simple y de bajo costo la D y estudiar su relación con el manejo del suelo.","palabras_clave":"flujo no saturado|sortividad|infiltración horizontal"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13537,"idioma_id":5,"titulo":"Evaluación de tratamientos térmicos en aceros comerciales AISI 304L y AISI 316L para implantes óseos","resumen":"Este trabajo presenta los resultados obtenidos al estudiar aceros inoxidables austeníticos, para determinar la factibilidad de ser utilizados en prótesis y órtesis óseas de bajo costo para uso veterinario. Muestras de aceros comerciales AISI 304L y AISI 316L fueron modificadas mediante tratamientos térmicos. Se llevaron a cabo tres tratamientos térmicos alternativos: (A) solubilizado, (B) solubilizado seguido de distensionado, y (C) solubilizado seguido de distensionado, más un segundo solubilizado. Luego de cada tratamiento térmico, se analizó la microestructura de las muestras, se evaluó la susceptibilidad a la corrosión intergranular y se realizaron ensayos de dureza, tracción y doblado.El análisis microestructural evidenció que ambos aceros inoxidables austeníticos experimentaron aumento del tamaño de granos. El tamaño de granos final fue similar en ambos tipos de aceros luego de cualquiera de los tres tratamientos térmicos. En el caso del AISI 316L, la resistencia a la tracción disminuyó un 10% luego del tratamiento A. Esta disminución fue menor luego de los tratamientos B o C. En contraste, la resistencia a la tracción se vio menos influenciada en AISI 304L, con disminuciones inferiores al 5%. Todos los tratamientos térmicos disminuyeron la dureza de ambos aceros en un 15% aproximadamente. Las probetas sometidas a ensayos de doblado no mostraron defectos ni discontinuidades. Los ensayos de susceptibilidad a la corrosión, realizados de acuerdo con la norma ASTM A262, indicaron que tanto AISI 316L como AISI 304L pueden aceptarse como libres de corrosión intergranular en todos los casos. Sin embargo, se observaron indicios de corrosión a largo plazo.","palabras_clave":"AISI 304L|AISI 316L|aceros inoxidables austeníticos|tratamientos térmicos|prótesis óseas|órtesis óseas"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13589,"idioma_id":4,"titulo":"Synchrotron radiation and absence of linear polarization in the colliding wind binary WR 146","resumen":"Context. Several massive early-type binaries exhibit non-thermal emission which has been attributed to synchrotron radiation from particles accelerated by diffusive shock acceleration (DSA) in the wind-collision region (WCR). If the magnetic field in the strong shocks is ordered, its component parallel to the shock front should be enhanced, and the resultant synchrotron radiation would be polarized. However, such polarization has never been measured. Aims: We aim to determine the percentage of linearly polarized emission from the well-known non-thermal radio emitter WR 146, a WC6+O8 system. Methods: We performed spatially-unresolved radio continuum observations of WR 146 at 5 cm and 20 cm with the Karl G. Jansky Very Large Array. We constructed a numerical model to investigate a scenario where particles are accelerated by turbulent magnetic reconnection (MR), and we performed a quantitative analysis of possible depolarization effects. Results: No linearly polarized radio emission was detected. The data constrain the fractional linear polarization to less than 0.6% between 1 to 8 GHz. This is compatible with a high level of turbulence and a dominant random component in the magnetic field. In this case the relativistic particles could be produced by turbulent magnetic reconnection. In order for this scenario to satisfy the required non-thermal energy budget, the strength of the magnetic field in the WCR must be as high as 150 mG. However, if the magnetic field is ordered and DSA is ongoing, then a combination of internal and external Faraday rotation could equally account for the depolarization of the emission. Conclusions: The absence of polarization could be caused by a highly turbulent magnetic field, other depolarization mechanisms such as Faraday rotation in the stellar wind, or a combination of these processes. It is not clear whether it is possible to develop the high level of turbulence and strong magnetic fields required for efficient MR in a long-period binary such as WR 146. This scenario might also have trouble explaining the low-frequency cutoff in the spectrum. We therefore favor a scenario where particles are accelerated through DSA and the depolarization is produced by mechanisms other than a large ratio between random to regular magnetic fields.","palabras_clave":"Polarization| Radio continuum: stars | Radiation mechanisms: non-thermal |Stars: individual: WR 146| Stars: winds, outflows"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13606,"idioma_id":5,"titulo":"Un doble P.A.S.O. electoral. Análisis del debut del sistema de primarias abiertas y de la doble vuelta electoral en las elecciones presidenciales argentinas de 2015","resumen":"Este trabajo se centrará en el análisis de dos instrumentos institucionales que formaron parte de la agenda reformista latinoamericana de las décadas pasadas (primarias\/internas abiertas y sistema de doble vuelta electoral) conel objeto de, no sólo exhibir los efectos aislados de cada uno de ellos, sino básicamentede examinar con rigurosidad las consecuencias de la aplicación concurrente de ambos. Estos dos mecanismos se orientan a propósitos análogos: brindar a los ciudadanos más instancias demanifestación de preferencias, proveer de mejores condiciones democráticas a los partidos, incrementar la legitimidad popular de los candidatos consagrados, etc. Sin embargo, la incorporación formal e implementación conjunta de ambos ha dado lugar a la conformación de un proceso de (dos o) tres fases para las eleccionespresidenciales, cuyos corolarios finales pueden entrar en &nbsp;contradicción con aquellos objetivos iniciales.En esta pesquisa se estudiará la elección presidencial argentina de 2015, en la cual por primera vez -y única hasta ahora- en lahistoria (después de 21 años de la instauración de la doble vuelta y seis añosde la incorporación de primarias abiertas simultáneas y obligatorias), elsistema electoral no sólo tuvo un formato trifásico, sino que operó efectivamente con una mecánica de tres vueltas eleccionarias.Finalmente, se evaluarán los resultados y se procurará determinar si la utilización conjunta de estas dos técnicas institucionales -consideradas como alternativas adecuadas para obtener ciertos resultados- potencia o cohíbe la satisfacción de los propósitos deseados.","palabras_clave":"PRIMARIAS ABIERTAS|DOBLE VUELTA ELECTORAL|ELECCIONES 2015|PROCESO TRIFÁSICO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13607,"idioma_id":5,"titulo":"Un PASO decisivo. Los partidos de izquierda después de la reforma electoral en la Argentina","resumen":"En el presente trabajo se analizan los efectos de la implementación del sistema de primarias abiertas, simultáneasy obligatorias (PASO), una de las piezas clave de la reforma político-electoral,sancionada en 2009 en Argentina. Según sus patrocinadores, con esta reforma selograrían, básicamente, los siguientes objetivos: la democratización de las estructuraspartidarias, el ordenamiento de la oferta política yla politización de la ciudadanía.Eneste trabajo se estudiará la adaptación de las fuerzas políticas de izquierda alas nuevas normativas, a lo largo de los tres procesos eleccionarios en los quefueron aplicadas las PASO. Enlas dos primeras aplicaciones del sistema de PASO, el FIT logró sobreponerse alas limitaciones impuestas con la reforma electoral. En 2015, en cambio, lacompetencia fratricida, la adaptación al electoralismo y la vulneración de losequilibrios preexistentes, constituyeron un freno en el proceso de ascenso dela izquierda revolucionaria.","palabras_clave":"PARTIDOS DE IZQUIERDA|FRENTE DE IZQUIERDA|PRIMARIAS ABIERTAS|LEY ELECTORAL 26.571"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13625,"idioma_id":4,"titulo":"Polymeric antigen BLSOmp31 in aluminium hydroxide induces serum  bactericidal and opsonic antibodies against Brucella canis in dogs","resumen":"Polymeric antigen BLSOmp31 is an immunogenic vaccine candidate that confers protection against Brucella canis in mice. In this preliminary study, the immunogenicity and safety of BLSOmp31 adsorbed to aluminum hydroxide gel (BLSOmp31-AH) were evaluated in Beagle dogs. In addition, the potential to elicit serum antibodies with complement-dependent bactericidal activity and\/or to enhance phagocytosis by neutrophils were analyzed. Dogs were immunized three times with BLSOmp31-AH by subcutaneous route, followed by an annual booster. The vaccine elicited specific antibodies 3 weeks after the first immunization. Annual booster induced comparable antibody response as the primary series. Humoral immune response stimulated by BLSOmp31-AH did not interfere with routine agglutination test for canine brucellosis. Antibodies demonstrated a high complement-dependent bactericidal activity against B. canis. Moreover, opsonization by immune serum not only stimulated binding and uptake of the bacteria by neutrophils but effectively enhanced the destruction of B. canis. Specific IgG was detected in 3\/4 immunized dogs in preputial secretions. The antibody profile corresponded to a marked Th2 response, since IgG1 prevailed over IgG2 and cellular immune response was not detected in vitro or in vivo. These results require further evaluation in larger field studies to establish the full prophylactic activity of BLSOmp31 against canine brucellosis.","palabras_clave":"BLSOMP31|ALUMINUM HYDROXIDE|CANINE BRUCELLOSIS|DOG|OPSONIC ANTIBODIES|BACTERIOLYTIC ANTIBODIES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13648,"idioma_id":4,"titulo":"Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV","resumen":"Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the heterologous prime-boost approach using recombinant modified vaccinia Ankara virus (rMVA), which has shown promising results in both mammals and chickens, has not been tried against this pathogen yet. IBD is a highly contagious and immunosuppressive disease of poultry that affects mainly young chicks. It is caused by IBDV, a double-stranded RNA virus carrying its main antigenic epitopes on the capsid protein VP2. Our objective was to evaluate the immune response elicited by two heterologous prime-boost schemes combining an rMVA carrying the VP2 mature gene (rVP2) and a recombinant VP2 protein produced in Nicotiana benthamiana (pVP2), and to compare them with the performance of the homologous pVP2-pVP2 scheme usually used in our laboratory. The SPF chickens immunized with the three evaluated schemes elicited significantly higher anti-VP2 antibody titers (p<0.001) and seroneutralizing titers (p<0.05) and had less T-cell infiltration (p<0.001), histological damage (p<0.001) and IBDV particles (p<0.001) in their bursae of Fabricius when compared with control groups. No significant differences were found between both heterologous schemes and the homologous one. However, the rVP2-pVP2 scheme showed significantly higher anti-VP2 antibody titers than pVP2-rVP2 and a similar tendency was found in the seroneutralization assay. Conversely, pVP2-rVP2 had the best performance when evaluated through bursal parameters despite having a less potent humoral immune response. These findings suggest that the order in which rVP2 and pVP2 are combined can influence the immune response obtained. Besides, the lack of a strong humoral immune response did not lessen the ability to protect from IBDV challenge. Therefore, further research is needed to evaluate the mechanisms by which these immunogens are working in order to define the combination that performs better against IBDV.","palabras_clave":"AVIAN IMMUNE RESPONSE|SUBUNIT VACCINE|RECOMBINANT MVA|IBDV"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13666,"idioma_id":4,"titulo":"Consumption pattern of bromadiolone in presence of alternative food by house mice (Mus musculus) infesting poultry farms","resumen":"Poultry farms in Central Argentina are often infested by Mus musculus L., despite the regular application of the rodenticide bromadiolone. This failure may be explained by the consumption pattern of mice, which may prefer alternative foods available on the farms to bromadiolone baits. Here we examine the consumption pattern of bromadiolone in the presence of wheat by M. musculus infesting poultry farms compared with the laboratory CF1 mouse strain. Overall, the poultry farm mice had longer survival and lower total food consumption in comparison with the CF1 mice. On the first day of the experiment, rodents from both strains and sexes consumed bromadiolone in the same proportion as wheat. On the second day, female mice of both origins showed a significant decrease in the consumption of bromadiolone, while males kept that proportion constant. Despite the consumption differences between males and females, survival rates were not different. We concluded that rodents from farms behaved as if they had never been in contact with bromadiolone, since they showed the same pattern of poison consumption that the CF1 mice. Females may have associated physical upset with the consumption of bromadiolone, since they decreased its consumption relative to wheat. However, this consumption pattern did not help them to achieve higher survival than males. On poultry farms, the balanced food fed to chickens may function as an alternative food to the poison for rodents. Therefore, we propose that rodenticide should be applied during downtime, when shed are cleaned and there is no chicken feed, which could be used as alternative food.","palabras_clave":"Poultry Farms|Mus musculus|rodent control|rodenticides"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13722,"idioma_id":4,"titulo":"Use of shell shape variation as an assessment tool in the southernmost razor clam fishery","resumen":"Morphological variation provides a method for phenotypic stock differentiation at inter- and intra-specific levels. Various methods are used for the assessment of fishery stocks in mollusks; one of them is geometric morphometrics. We analyzed morphological variation in razor clams at ten fishing grounds, five from the Argentinean North Patagonian gulfs and five from Chile, and evaluated the occurrence of phenotypic stocks between Argentinean and Chilean fisheries, using geometricmorphometrics methods. The Argentinean harvesting of Ensis macha is emerging, and represents a way to diversify the shellfisheries in north Patagonia. Nevertheless, fishing and aquaculture play important roles for the Chilean economy. Various multivariate methods were applied to describe the differences among and between fishing grounds. We found significant differences in the average shell shape of individuals from either ocean, and these differences principally describe changes in the robustness of the shell. The average shell shapes differed among sites from the Pacific while those from the Atlantic Ocean did not show statistical differences. This study shows that geometric morphometric techniques are appropriate for the identification of phenotypic stocks in E. macha. Our results could be used for future resource management and to determine the origin of the product in razor clams from South America.","palabras_clave":"PHENOTYPIC STOCK|LANDMARKS|SHELL SHAPE VARIATION|SOUTH AMERICA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13723,"idioma_id":4,"titulo":"Environment-specific shell shape variation in the boring mytilid Lithophaga patatonica (d'Orbigny, 1842)","resumen":"Environmental conditions induce phenotypic responses (behavioural, morphological and physiological) in many marine species. The boring mytilid Leiosolenus patagonicus inhabits different types of substrata, such as sandstone intertidal and hard subtidal substrata (here called ?lifeless-substratum?) and shells of bivalve species (here called ?live-substratum?), where they are exposed to different restrictions in their growth. We used geometric morphometric methods to compare the contour shell shapes from each type of substratum (live and lifeless) since we expected the body shape to differ between individuals from these different substrata. The results showed that the shell shape depends on the type of substratum where the larvae recruit. The mean shell shapes of individuals from the live-substratum are more slender than those of the individuals growing inside the lifeless-substratum. Individuals from live-substratum can adapt their phenotype depending on the oyster?s anti-parasitism responses, while in lifeless-substratum they are able to build their own refuges.","palabras_clave":"GEOMETRIC MORPHOMETRICS|PATAGONIA|BIVALVES|SUBSTRATA|INTERTIDAL|SUBTIDAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13724,"idioma_id":4,"titulo":"Shell shape as a biomarker of marine pollution historic increase","resumen":"Buccinanops globulosus is a TBT sensitive marine gastropod, classified as a good indicator of imposex incidence and used as a model to study adverse contamination effects. Population and maritime industries has incremented pollution in Nuevo gulf harbor since 1970s, promoting morphological changes in B. globulosus shell shape. We study the shell shape of the species comparing present day´s specimens from the harbor zone with those collected in the same zone before the increasing of maritime activity and pre-hispanic archeological Middens. We demonstrated that harbor pollution produces globular shell shape in B. globulosus, an effect that probably allows gastropods to isolate themselves from the external adverse environment. On the contrary, shells from pre-hispanic periods, unpolluted sites and those collected before the expansion of maritime activities, presented an elongated shell shape. Our study confirms that shell shape variation in marine gastropods can be used as a biomarker of harbor pollution.","palabras_clave":"GASTROPOD SHELL|GEOMETRIC MORPHOMETRICS|PATAGONIA|HARBOR POLLUTION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13732,"idioma_id":4,"titulo":"First evidence of Thaumastocoris peregrinus (Heteroptera: Thaumastocoridae) feeding from mesophyll of Eucalyptus leaves","resumen":"The bronze bug, Thaumastocoris peregrinus (Heteroptera: Thaumastocoridae) originally restricted to Australia, is an important emerging pest of Eucalyptus plantations in the Southern hemisphere. It feeds on mature leaves, causing the loss of photosynthetic surface area and defoliation and, according to some studies, even tree death. In this work, feeding activities of T. peregrinus on Eucalyptus camaldulensis leaves and its primarily food resource were identified. In cross sections of leaves, solid salivary deposits on epidermal cells and in close vicinity to stomata cells were detected. In subepidermal cells of the palisade parenchyma near the stylet penetration point, disorganization and removal of chloroplasts were also observed. The presence of chlorophyll in guts of adults and nymphs was analyzed using spectrophotometry and confocal laser scanning in order to obtain in situ fluorescent spectra. Both spectra showed chlorophyll absorbance peaks. In addition the presence of chlorophyll in guts of T. peregrinus using fluorescence microscopy was identified. These results provide the first evidence that T. peregrinus feeds from the palisade parenchyma (chlorenchyma) of eucalyptus leaves.","palabras_clave":"bronze bug|feeding behaviour|mesophyll|salivary deposits"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13734,"idioma_id":5,"titulo":"Demanda y déficit habitacional en San Carlos de Bariloche (2015)","resumen":"Este artículo tiene como objetivo realizar un cálculo de la demandahabitacional de la ciudad de San Carlos de Bariloche en función dela cantidad de nuevos hogares que se crean año a año y el déficithabitacional acumulado existente. Asimismo, se estima la cantidad deviviendas que produce el mercado en los últimos años para estimarel esfuerzo que debe hacer el Estado y las organizaciones socialespara atender el remanente de la demanda habitacional. Finalmente sereflexiona en función del modelo de desarrollo urbano de la ciudad,en virtud de que la tierra de expansión está agotándose, por loque se sugiere que las políticas urbanas deben encaminarse apromover una mayor densificación de la trama urbana. ","palabras_clave":"Demanda Habitacional|Déficit Habitacional|Políticas Urbanas"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13737,"idioma_id":4,"titulo":"An evolutionary approach towards contact plan design for disruption-tolerant satellite networks","resumen":"Delay and disruption tolerant networks (DTNs) are becoming an appealing solution for satellite networks where nodes can temporarily store and carry in-transit data until a link with a suitable next-hop becomes available. Since satellite trajectories and orientation can be predicted, on-board routing schemes can base these forwarding decisions on a contact plan comprising all forthcoming communication opportunities. In general, contact plans are previously calculated on ground where their design can be optimized to consider not only available spacecraft resources but also the expected traffic which is largely foreseeable in space applications. Despite optimal contact plan design procedures exist, their computation complexity might result prohibitive even for medium-sized satellite networks. In this work, we propose an evolutionary algorithm to provide sub-optimal yet efficient and implementable contact plans in bounded time. In particular, we depict specific strategies such as encoding and repairing techniques to later evaluate the algorithm performance in a typical scenario demonstrating its usefulness for planning future DTN-based satellite networks.","palabras_clave":"Delay tolerant networks|Contact plan design|Evolutionary algorithms"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13740,"idioma_id":4,"titulo":"Analysis and use of cumulative nutrient uptake formulas in plant nutrition and the temporal weight averaged influx","resumen":"A generalized cumulative uptake formula of nutrient uptake by rootsfollowing our previous formula (Reginato-Tarzia, Comm. Soil Sci. and Plant.,33 (2002), 821-830) is developed. Cumulative nutrient uptake obtained bythis formula is compared with the simulated results obtained by the Claassenand Barber (Claassen and Barber, Agronomy J., 68 (1976) 961?964) andCushman (Cushman, Soil Sci. Soc., 43 (1979) 1087?1090) formulas. A massbalance is analyzed for the three formulas of cumulative nutrient uptake inorder to decide which of them is correct. Moreover, the mass balance is alsoverified through a computational algorithm using data obtained fromliterature, and we compute the potassium (K) uptake for maize for low andhigh soil concentrations using the three mentioned formulas. The theoreticalanalysis shows that Claassen and Barber, and Cushman formulas do notverify, in general, the mass balance condition. The Claassen and Barberformula only verifies this condition when the influx is constant and rootgrows linearly. The Cushman formula verifies the mass balance when theinflux is constant regardless of the law of root growth. Reginato and Tarziaformula always verifies the mass balance whatever be the representativefunctions for the influx and the law of root growth. Moreover, we propose aredefinition of the averaged influx from which the Williams formula (Williams,J. Scientific Res., 1 (1948) 333?361) can be deduced. We remark that Williamsformula is a consequence of our definition of temporal-weight-averagedinflux for all root growth law expressions. Also, we present a comparison ofinflux and cumulative uptake of cadmium (Cd) with data extracted fromliterature. Cumulative uptake is obtained through the Barber?Cushmanmodel and our moving boundary model by using the redefinition ofaveraged influx on root surface and the correct cumulative uptake formulapresented in this paper.","palabras_clave":"cumulative nutrient uptake|mass balance|nutrient influx|Williams's formula"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13774,"idioma_id":5,"titulo":"El Aprendizaje Servicio en universidades de Buenos Aires: avanzando hacia su institucionalización","resumen":"El aprendizaje servicio está teniendo una amplia difusión en el panoramainternacional; si nos centramos en su desarrollo en el seno de la Educación Superior,más concretamente dentro del contexto Latinoamericano, indudablemente debemoshacer referencia a la universidad argentina. Una reciente estancia investigadora yformativa en la provincia de Buenos Aires nos ha permitido acercarnos a la realidadque diferentes universidades presentan en la inserción del aprendizaje servicio dentrode sus estructuras. La revisión de documentación institucional, la visita a diferentesproyectos y sobre todo, las entrevistas con diversos agentes implicados en suinstauración y desarrollo, han sido de ayuda para entender el nivel deinstitucionalización que esta propuesta está alcanzando, así como los retos que sepresentan a futuro. Todo esto se refleja en el análisis realizado y en unas conclusionesque recogemos a modo de cierre","palabras_clave":"EDUCACION SUPERIOR|INSTITUCIONALIZACION|EXTENSION UNIVERSITARIA|RESPONSABILIDAD SOCIAL UNIVERSITARIA|APRENDIZAJE SERVICIO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13784,"idioma_id":4,"titulo":"Recent developments in chemistry, coordination, structure and biological aspects of 1-(acyl\/aroyl)-3-(substituted) thioureas","resumen":"1-(Acyl\/aroyl)-3-(substituted)thioureas are privileged architectures that have received remarkable attention of researchers in view of their variable topological aspects, binding modes and broad spectrum promising pharmacological properties. Reactivity of acyl thiourea derivatives has presented various organic transformations into other demanding scaffolds and this is an attractive strategy for synthetic chemists to access heterocyclic cores. Multiple binding sites make them flexible ligands for complexation with transition metals thus occupying a distinct position in coordination chemistry. 1-(Acyl\/aroyl)-3-(substituted)thioureas have also emerged as attractive candidates in various fields such as ion sensors, corrosion inhibitors, molecular electronics, in metal extraction and in pharmaceuticals. The medicinal chemistry of this organo-sulfur framework and the derived metal complexes has witnessed fantastic progress in the current era. In continuation of our efforts to compile data on the structural aspects and numerous applications of 1-(acyl\/aroyl)-3-(substituted)thiourea analogs, continuous advances have prompted us to present an overview of the last 2 years literature on this exciting family of compounds through this review article.","palabras_clave":"THIOUREAS|STRUCTURE|SYNTHESYS|APPLICATIONS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13795,"idioma_id":4,"titulo":"Petrogenesis of Quebrada de la Mina and Altar North porphyries (Cordillera of San Juan, Argentina): Crustal assimilation and metallogenic implications","resumen":"We investigate the geology of Altar North (Cu-Au) and Quebradade la Mina (Au) porphyry deposits located in San Juan Province(Argentina), close to the large Altar porphyry copper deposit (995 Mt,0.35% Cu, 0.083 g\/t Au), to present constraints on the magmatic processesthat occurred in the parental magma chambers of these magmatichydrothermalsystems.Altar North deposit comprises a plagioclase-amphibole-phyric daciteintrusion (Altar North barren porphyry) and a plagioclase-amphibolebiotite-phyric dacite stock (Altar North mineralized porphyry, 11.98 ±0.19 Ma). In Quebrada de la Mina, a plagioclase-amphibole-biotite-quartzphyricdacite stock (QDM porphyry, 11.91 ± 0.33 Ma) crops out.High Sr\/Y ratios (92-142) and amphibole compositions of Altar Northbarren and QDM porphyries reflect high magmatic oxidation states (fO2=NNO +1.1 to +1.6) and high fH2O conditions in their magmas. Zones andrims enriched in anorthite (An37-48), SrO (0.22-0.33 wt. %) and FeO(0.21-0.37 wt. %) in plagioclase phenocrysts are evidences of magmaticrecharge processes in the magma chambers.Altar North and Quebrada de la Mina intrusions have relativelyhomogeneous isotopic compositions (87Sr\/86Sr(t) =0.70450-0.70466, &#949;Nd(t)= +0.2to +1.2) consistent with mixed mantle and crust contributions intheir magmas. Higher Pb isotopes ratios (207Pb\/204Pb = 15.6276-15.6294)of these intrusions compared to other porphyries of the district, reflectan increase in the assimilation of high radiogenic Pb components in themagmas. Ages of zircon xenocrysts (297Ma, 210Ma, 204Ma, 69 Ma) revealedthat the magmas have experienced assimilation of Miocene, Cretaceous,Triassic and Carboniferous crustal rocks. Fluids that precipitated sulfides in the Altar deposit may have remobilized Pb from the host rocks, as indicated by the ore minerals being more radiogenic (207Pb\/204Pb = 15.6243-15.6269) than their host intrusions. Au\/Cu ratio in Altar porphyries (average Au\/Cu ratio of 0.14× 10-4 by weight in Altar Central) is higher than in the giant Mioceneporphyry deposits located to the south: Los Pelambres, Río Blanco and LosBronces (Chile) and Pachón (Argentina). We suggest that the increase inAu content in the porphyries of this region could be linked to theassimilation of high radiogenic Pb components in the magmas within theselong-lived maturation systems.","palabras_clave":"PORPHYRY|HIGH SULFIDATION EPITHERMAL|MAGMATIC RECHARGE|RADIOGENIC ISOTOPES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13799,"idioma_id":4,"titulo":"Blowout jets and impulsive eruptive flares in a bald-patch topology","resumen":"Context. A subclass of broad extreme ultraviolet (EUV) and X-ray jets, called blowout jets, have become a topic of research since they could be the link between standard collimated jets and coronal mass ejections (CMEs).Aims. Our aim is to understand the origin of a series of broad jets, some of which are accompanied by flares and associated with narrow and jet-like CMEs.Methods. We analyze observations of a series of recurrent broad jets observed in AR 10484 on 21?24 October 2003. In particular, one of them occurred simultaneously with an M2.4 flare on 23 October at 02:41 UT (SOLA2003-10-23). Both events were observed by the ARIES H&#945; Solar Tower-Telescope, TRACE, SOHO, and RHESSI instruments. The flare was very impulsive and followed by a narrow CME. A local force-free model of AR 10484 is the basis to compute its topology. We find bald patches (BPs) at the flare site. This BP topology is present for at least two days before to events. Large-scale field lines, associated with the BPs, represent openloops. This is confirmed by a global potential free source surface (PFSS) model. Following the brightest leading edge of the H&#945; and EUV jet emission, we can temporarily associate these emissions with a narrow CME.Results. Considering their characteristics, the observed broad jets appear to be of the blowout class. As the most plausible scenario, we propose that magnetic reconnection could occur at the BP separatrices forced by the destabilization of a continuously reformed flux rope underlying them. The reconnection process could bring the cool flux-rope material into the reconnected open field lines driving the series of recurrent blowout jets and accompanying CMEs.Conclusions. Based on a model of the coronal field, we compute the AR 10484 topology at the location where flaring and blowout jets occurred from 21 to 24 October 2003. This topology can consistently explain the origin of these events.","palabras_clave":"FLARES|BLOWOUT JETS|MAGNETIC FIELD MODEL|MAGNETIC TOPOLOGY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13866,"idioma_id":4,"titulo":"Best simultaneous approximation in the $L^p$ norms","resumen":"We study the behavior of the best simultaneousapproximation to two functions froma convex set in $L^p$ on a union of intervals, when $2 < p < infty$and the measure of them tends to zero.In particular, we give sufficientconditions over the differentiability  of two functions to assureexistence  of the best simultaneouslocal approximation in $L^p$, from the class of algebraicpolynomials of a fixed degree. These conditions  are weaker  thanthe ordinary differentiability given in previous works. Moreprecisely, we consider differentiable functions in the sense $L^p.$","palabras_clave":"SIMULTANEOUS APPROXIMATION|BEST LOCAL APPROXIMATION|DIFFERENTIABILITY|CONVEX SETS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13868,"idioma_id":4,"titulo":"An extension on best L2 local approximation","resumen":"We introduce two classes of functions, one containing the classof L2 differentiable functions, and another containing the class of L2 lateraldifferentiable functions. For functions in these new classes we prove existenceof best local approximation at several points. Moreover, we get results aboutthe asymptotic behavior of the derivatives of the net of best approximations,which are unknown even for L2 differentiable functions.","palabras_clave":"BEST LOCAL APPROXIMATION|TAU CONDITION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13869,"idioma_id":4,"titulo":"Epithelial ovarian cancer diagnosis of second harmonic generation images: A semi-automatic collagen fibers quantification protocol","resumen":"A vast number of human pathologic conditions are directly or indirectly related to tissular collagen structure remodeling. The nonlinear optical microscopy second-harmonic generation has become a powerful tool for imaging biological tissues with anisotropic hyperpolarized structures, such as collagen. During the past years, several quantification methods to analyze and evaluate these images have been developed. However, automated or semiautomated solutions are necessary to ensure objectivity and reproducibility of such analysis. This work describes automation and improvement methods for calculating the anisotropy (using fast Fourier transform analysis and the gray-level co-occurrence matrix). These were applied to analyze biopsy samples of human ovarian epithelial cancer at different stages of malignancy (mucinous, serous, mixed, and endometrial subtypes). The semiautomation procedure enabled us to design a diagnostic protocol that recognizes between healthy and pathologic tissues, as well as between different tumor types.","palabras_clave":"FFT|GLCM microscopy|Human cancer ovary|Diagnostic protocol"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13879,"idioma_id":4,"titulo":"Kisspeptin system in pejerrey fish (Odontesthes bonariensis). Characterization and gene expression pattern during early developmental stages","resumen":"In vertebrates, kisspeptins and their receptors are known to be related to puberty onset and gonadal maturation, however, there are few studies concerning their role in early development. Here, we characterize the kisspeptin system in the pejerrey, Odontesthes bonariensis, a fish with strong temperature-dependent sex determination. We reconstructed the phylogenetic history of the two ligands (kiss1 and kiss 2) and two receptors (kissr2 and kissr3) in pejerrey in the context of recent classifications of bony fishes, determined their tissue distribution and documented the early expression pattern of these ligands and receptors. Phylogenetic analysis of these gene families clearly resolved the percomorph clade and grouped pejerrey with Beloniformes. Paralogous sets of genes putatively arising from the teleost-specific genome duplication event (3R) were not detected. Kisspeptins and their receptors showed a wide tissue distribution in adult pejerrey, including tissues not related to reproduction. In larvae reared at 24&nbsp;&deg;C, the four kisspeptin elements were expressed in the head from week 1 to week 8 of life, with no differences in transcript levels. Larvae kept at a female-producing temperature (17&nbsp;&deg;C) did not show statistically significant differences in the transcript levels of all analyzed genes during the sex determination\/differentiation period; however, in those larvae raised at male producing temperature (29&nbsp;&deg;C), kiss2 levels were increased at week 4 after hatching. These results showed that all members of the kisspeptin system are expressed at this early period, and the increase of kiss2 transcripts at week 4 could be interpreted as it would be related to the differentiation of the brain-pituitary axis in male development.","palabras_clave":"KISSPEPTIN|KISSPEPTIN RECEPTOR|PEJERREY FISH|PHYLOGENY|SEX DIFFERENTIATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13892,"idioma_id":5,"titulo":"Las empresas de servicios en América Latina: un estudio exploratorio sobre factores de competitividad internacional, obstáculos y políticas públicas","resumen":"Desde hace tiempo los servicios son un sector dominante en la economía global, puesto que dan cuenta de la mayor parte del producto interno bruto y el empleo tanto en las economías desarrolladas como en buena parte del mundo en desarrollo. En los últimos años, a su vez, los servicios han incrementado su peso tanto en el comercio internacional como en los flujos de inversiones externas. Si bien las empresas latinoamericanas han comenzado a participar activamente de esta nueva dinámica global y varios de los países de la región muestran un dinamismo apreciable en sus exportaciones de servicios, todavía hay importantes espacios de mejora para profundizar estas tendencias y escalar posiciones. El presente trabajo se basa en una encuesta a empresas de servicios de América Latina en la que se indagó acerca de la visión de las propias firmas respecto de los obstáculos para el comercio de servicios, como así también sobre la cobertura e impacto de las políticas públicas existentes en los países de la región que influyen sobre dicho comercio. De aquí, pueden derivarse algunos lineamientos de política útiles para promover el desarrollo de las exportaciones de servicios en Latinoamérica.","palabras_clave":"Empresas de servicios|Políticas públicas|Competitividad|Exportaciones|América Latina"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13911,"idioma_id":4,"titulo":"The role of core electrons in quantum dynamics using TDDFT","resumen":"The explicit simulation of time dependent electronic processes requires computationally onerous routes involving the temporal integration of motion equations for the charge density. Efficiency optimization of these methods typically relies on increasing the integration time-step and on the reduction of the computational cost per step. The implicit representation of inner electrons by effective core potentials-or pseudopotentials-is a standard practice in localized-basis quantum-chemistry implementations to improve the efficiency of ground-state calculations, still preserving the quality of the output. This article presents an investigation on the impact that effective core potentials have on the overall efficiency of real time electron dynamics with TDDFT. Interestingly, the speedups achieved with the use of pseudopotentials in this kind of simulation are on average much more significant than in ground-state calculations, reaching in some cases a factor as large as 600×. This boost in performance originates from two contributions: on the one hand, the size of the density matrix, which is considerably reduced, and, on the other, the elimination of high-frequency electronic modes, responsible for limiting the maximum time-step, which vanish when the core electrons are not propagated explicitly. The latter circumstance allows for significant increases in time-step, that in certain cases may reach up to 3 orders of magnitude, without losing any relevant chemical or spectroscopic information.","palabras_clave":"TDDFT|pseudopotentials|excitations|electrons"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13919,"idioma_id":4,"titulo":"Delving into the secular stagnation hypothesis. A firm-level analysis of the private sector´s excess savings in advanced economies.","resumen":"We document a persistent increase of excess savings (defined as the difference between gross savings and capital formation), and a steady decline of gross capital formation in a sample of non-financial firms from developed countries. These patterns developed even before the financial breakdown of 2007 reinforcing the case for a secular stagnation hypothesis. They go along with a deleveraging process and a decrease in the share of operating assets in total assets. We discuss three possible explanations for this long term behavior: financial constraints, operative volatility and the weakening of business dynamism itself.","palabras_clave":"SECULAR STANGATION|INVESTMENT|SAVINGS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13922,"idioma_id":5,"titulo":"Actitudes de los adultos mayores de la Ciudad de Buenos Aires ante las políticas y los programas para la vejez","resumen":"La política social implica intervención del Estado para redistribuir y resolver aspectos del Bienestar Social. Una política sobre la vejez debe mantener y aumentar la independencia de las personas de edad, extender y mejorar las medidas de readaptación y encontrar respuestas para la fragilidad. La población objetivo de las políticas sociales construyen actitudes, percepciones y creencias que condicionan la valoración y la utilización de los planes sociales. Objetivo: conocer el grado de utilización, conocimiento y actitud que tienen las personas de mayor edad sobre los planes sociales para la vejez. Metodología: se realizó un estudio cuantitativo, transversal, descriptivo y exploratorio sobre personas de 60 y más años de la Ciudad de Buenos Aires. Se diseñó un cuestionario con 40 ítems y se realizó un muestreo probabilístico multietápico: estratificado, conglomerado (puntos muestras), sistemático (vivienda) y de azar simple (entrevistado). La muestra quedó conformada por 565 encuestados.Se aplicó una escala Likert con 20 dimensiones para observar las actitudes con respecto a la visibilidad, accesibilidad y utilización de los planes sociales.Resultados y conclusiones: los resultados muestran que existe una carencia importante de conocimiento sobre las prestaciones y su uso. Con respecto a la actitud se observó que los adultos mayores más vulnerables, tanto por su situación socioeconómica, de viudez o su mayor edad, fueron quienes tuvieron una visión positiva con respecto a los planes, debido a su potencial o real necesidad de uso. En contraste los sectores menos vulnerables y de mayor de poder adquisitivo mostraron una visión negativa de los planes estatales","palabras_clave":"ACTITUDES|PRESTACIONES SOCIALES|PERSONAS MAYORES|CIUDAD BUENOS AIRES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13924,"idioma_id":4,"titulo":"Module categories over equivariantized tensor categories","resumen":"For a finite tensor category C and a Hopf monad T : C &#8594;C satisfying certain conditions we describe exact indecomposable leftC^T-module categories in terms of left C-module categories and someextra data. We also give a 2-categorical interpretation of the process ofequivariantization of module categories.","palabras_clave":"tensor category|module category|Hopf monad"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13935,"idioma_id":4,"titulo":"Validation of an enzyme immunoassay and comparison of fecal cortisol metabolite levels in black and gold howler monkeys (Alouatta caraya) inhabiting fragmented and continuous areas of the humid Chaco region, Argentina","resumen":"In the last years, the study of how environmental stimuli influence the physiology and specificallythe endocrinology of an organism became increasingly important, relying mainly on thequantification of glucocorticoids to monitor animal welfare. Most studies investigating cortisollevels in primates were focused on the impact of social stressors; however, a major concern forthe conservation of howler monkeys is the increased habitat fragmentation led by theadvancement of the agricultural frontier.We compared fecal cortisolmetabolite levels (FGCM) inhowler monkeys (Alouatta caraya) living in fragmented and continuous forests of the ArgentinehumidChaco region, throughout thewarm season (spring-summer). Fecal samples (n = 114) werecollected fromadult individuals, and steroid extracts analyzed with an enzyme immunoassay alsovalidated in this work. Parallel displacement curves were obtained between dilutions of pooledfecal extracts and the cortisol standard curve (r2 = 0.99; P=0.23). Efficiency of the fecalextraction procedure was 79.4%± 38%; recovery of exogenous hormone added to fecal extractsindicated a low interference of components in the feces with antibody binding. The exogenousadministration of ACTH in captive-bred animals demonstrated a ?cause-and-effect? relationshipbetween the adrenal gland activation and increased FGCM levels. Contrary to our initialprediction, we were not able to demonstrate a significant difference in FGCM levels of carayamonkeys inhabiting the continuous versus fragmented habitats in our study site (83.2 ± 4.9 ng\/g[n = 10 individuals] vs. 71.5 ± 4.9 ng\/g [n = 7 individuals]; P = 0.29); this could be the result of lowlevels of disturbance imposed by a moderate and selective logging, which has proved to bebeneficial for this species with high resilience by adjusting their diet to cope with feeding indegraded habitats but with new leaves and buds. Regardless of the habitat, cortisol metaboliteswere significantly higher in females than in males (86.4 ± 4.2 ng\/g [n = 12 individuals] vs.60.7 ± 5.0 ng\/g [n = 5 individuals] respectively; P = 0.007).","palabras_clave":"FRAGMENTATION|CORTISOL|FECES|GLUCOCORTICOIDS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13940,"idioma_id":4,"titulo":"Taxonomy of the bivalve Ptychomya in the Lower Cretaceous of the Neuquén basin (west-central Argentina)","resumen":"In the Lower Cretaceous Agrio Formation, Neuquén Basin (west-central Argentina), the highly variable genus Ptychomya Agassiz has challenged traditional taxonomists for over a century. We applied here a previously outlined quantitative protocol in order to settle the taxonomy of the genus based on specimens recorded from base to top of the Agrio Formation. The shell outline and ribbing pattern, two prominent external features of the valves, were quantified through geometric morphometrics of closed and open outlines, respectively. Search of morphological groups was attained using model-based clustering, and the possible presence of morphological gaps between them was statistically tested. Our results showed that the variation historically attributed to a single species, namely Ptychomya koeneni Behrendsen, corresponds to intra- and interspecific variability of at least four species, one of which was previously unknown (Ptychomya esbelta sp. nov.) whereas another was regarded as a subspecies of P. koeneni, namely Ptychomya windhauseni Weaver. We were also able to confirm the specific rank of Ptychomya coihuicoensis Weaver and the presence of P. koeneni in the Upper Hauterivian of the Agrio Formation. The present contribution is a significant improvement in terms of taxonomy and diversity of the genus Ptychomya in the Andes of Argentina and it is intended to stimulate studies in other poorly known cretaceous bivalve faunas from other Andean Basins of South America and improve the biostratigraphic usefulness and palaeobiogeographic significance of this pandemic bivalve taxon.","palabras_clave":"TAXONOMY|BIVALVIA|GEOMETRIC MORPHOMETRICS|CRETACEOUS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13958,"idioma_id":5,"titulo":"Techos Verdes. Contribución del Carpobrotus Acinaciformis al Manejo Integrado de Escurrimientos Superficiales Urbanos.","resumen":"En el marco de la modelización matemática de las cuencas hídricas urbanas, uno de los parámetros que es necesario conocer, son los factores en la cuenca que pueden modificar la escorrentía superficial. Las Cubiertas Naturadas pueden (a partir de su capacidad de retención y retardo de los escurrimientos originados por las precipitaciones), modificar la escorrentía superficial. Pero en qué medida pueden hacerlo, dependerá de la respuesta de dichas estructuras vegetadas a la cantidad precipitada y esta respuesta será diferente según el tipo de cubierta utilizada (básicamente espesor del sustrato y tipo de vegetación). Por eso en los modelos matemáticos de simulación, la modelización será más precisa en función de la precisión de los datos fuentes utilizados en la misma. El objetivo de este trabajo ha sido determinar la capacidad de retención que presentan las cubiertas naturadas de tipo extensivo e intensivo implantadas con Carpobrotus acinaciformis. Los resultados obtenidos permitirían afirmar, para las condiciones estudiadas, que el Carpobrutus acinaciformis, puede realizar un aporte a la disminución de los escurrimientos urbanos para ciudades ubicadas en la costa bonaerense como la de este trabajo.","palabras_clave":"Techos verdes|Retención hídrica|Modelos de simulación"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13968,"idioma_id":4,"titulo":"Autonomy and Capacity: About Human Rights of Older Persons in Dependency Situations","resumen":"This paper discusses the scope of the current Argentine legal model concerned with autonomy of older people who are in a state of dependency, as part of the Elder Law. So, it studies the juridical system of capacity and will -significant components of personal autonomy- and analyzes the regime of adult guardianship, support systems, assistance and representation for older people. To fulfill these aims, the research takes into account the new Argentine Civil and Commercial Code -which comes into force from August 2015-; the National Rights of Patients Act (No. 26,529) and the National Mental Health Act (No. 26,657). This article considers too the evolution of jurisprudence in this area and contemplates the connection of the normative system and judicial decisions with the Inter-American Convention on Protecting the Human Rights of Older Persons, approved by the General Assembly of the Organization of American States (OAS) on June 15 2015. Finally, in this paper it is considered the importance of the actual development of the International Convention on Human Rights of Older Persons of the United Nations to this field.Ageing Int (2017) 42:335?353","palabras_clave":"AUTONOMY|CAPACITY|WILL|DEPENDENCY SITUATION|GUARDIANSHIP|HUMAN RIGHTS|ELDER LAW"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":13988,"idioma_id":5,"titulo":"Desempeño en memoria de trabajo e indicadores comportamentales. Relaciones entre medidas directas e indirectas .","resumen":"Los objetivos de este trabajo son evaluar si la capacidad de los docentes de reconocer dificultades de Memoria de Trabajo (MT) en sus alumnos se relaciona con el rendimiento de estos en pruebas ejecutivas de MT, y analizar si las dificultades de MT percibidas por el docente se corresponden con presencia de problemas comportamentales de diverso tipo. Para ello se les administraron a un grupo de niños en edad escolar pruebas de MT verbal y MT viso-espacial y se tomaron dos cuestionarios a los docentes de los mismos (Escala Observacional de Memoria de Trabajo -WMRS- y Guía de Observación Comportamental-GOC). Los resultados indican que existen asociaciones entre el rendimiento de los niños en tareas ejecutivas e indicadores de fallos comportamentales en MT, y que estos fallos se relacionan también con problemas comportamentales como problemas atencionales, hiperactividad y auto-agresión.","palabras_clave":"MEMORIA DE TRABAJO|INDICADORES COMPORTAMENTALES|PERCEPCIÓN DOCENTE|ATENCIÓN|HIPERACTIVIDAD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14009,"idioma_id":5,"titulo":"El Estado y los derechos humanos en la Nueva Constitución Política del Estado Plurinacional de Bolivia","resumen":"En el presente trabajo analizo el modo en que Álvaro García Linera conceptualiza la transición del Estado boliviano, y muestro cómo la Nueva Constitución Política se inscribe en ese proceso. Desde la perspectiva de la gubernamentalidad marco que en la Constitución hay una nueva racionalidad de gobierno que avanza hacia la plurinacionalidad y abandona el neoliberalismo, pero la racionalidad que subyace al diagrama de los derechos humanos se mantiene en un registro eminentemente liberal","palabras_clave":"ESTADO|GUBERNAMENTALIDAD|DERECHOS HUMANOS|LIBERALISMO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14010,"idioma_id":5,"titulo":"Presidencialismo y poder económico en la reforma constitucional argentina de 1994","resumen":"En su misión histórica del limitar al poder, el constitucionalismo reduce el poder al Estado. En el presente trabajo presentaré el proceso de concentración de poder que se desarrolló durante los primeros años del gobierno de Carlos Menem en Argentina: concentración de poder en el Presidente, y en las corporaciones económicas. Ante este contexto, los proyectos de reforma constitucional y los debates previos a la reforma de 1994, atendieron el poder del Presidente pero olvidaron el poder del capital privado.","palabras_clave":"CONSTITUCIONALISMO|PRESIDENCIALISMO|PODER ECONÓMICO|REFORMA CONSTITUCIONAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14013,"idioma_id":4,"titulo":"Estimation of the surface thermal resistances and heat loss by conduction using thermography","resumen":"The thermal insulation of a construction is established by the resistances of the materials employed and the thermal surface resistances, which may vary significantly from one building to another because of its location and climatic conditions. The importance of the surface resistances has been underestimated probably due to its complex calculation and variability since they depend on the differences of temperature and humidity, wind, shape of the envelope, surrounding obstacles such as trees, and other buildings. In this work, infrared thermography is employed to obtain the internal and external surface temperatures of the fa&ccedil;ades of a representative construction as part of a methodology to quantify the heat loss by conduction through the building envelope. U-values that encompass the characteristics of the envelope components and the thermal surface resistances are used. It is found that the thermal resistances of the air boundary layers vary during the day and, in most cases, are much greater than the values currently suggested by local regulations, thus significantly reducing the effective thermal conductivity of the envelope with respect to the design value. The findings show how important it is to quantitatively determine the heat flux through the building envelope on site for an already existing construction and corroborate the value estimated in the design stage.","palabras_clave":"Infrared thermography|Heat loss|Surface thermal resistances|In-situ measurements"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14017,"idioma_id":4,"titulo":"CURE KINETICS OF BUTYL RUBBER CURED BY PHENOL FORMALDEHYDE RESIN","resumen":"The characterization of rubber compounds is a necessary step for Simulating rubber products manufacturing processes. We study experimentally and model computationally compounds of Butyl rubber cured by Phenol Formaldehyde Resin, a rubber used for making curing bladders, a key component in the tire industry. Several compounds, differing in the proportions of resin, Zinc Oxide, Polychloroprene (CR) and Stearic Acid, are experimentally tested during the curing process using a moving die rheometer. The experimental results are used to find the parameters of two well established kinetic models, namely the Nth order and the Kamal-Sourour models. Both models include an ordinary differential equation for the degree of cure and an algebraic relation between torque and temperature. The fitting of the model parameters is rearranged as an optimization problem, and solved using the Levenberg-Marquadt algorithm. The results show that both models are able to represent the behavior of these compounds, although the more involved Kamal-Sourour model performs better for early times, as expected. The parameter values found are useful for numerical simulations of curing bladder manufacturing processes, and as a reference for further studies of similar compounds.","palabras_clave":"BUTYL RUBBER|VULCANIZATION|KINETIC MODEL|LEVENBERG-MARQUARDT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14030,"idioma_id":4,"titulo":"Biotechnologies for inclusive development: scaling-up, knowledge intensity and empowerment (the case of the probiotic yoghurt ?Yogurito? in Argentina)","resumen":"This paper analyses how technological and institutional innovation strategies were deployed towards achieving a high-scale, sustainable, knowledge intensive, locally grounded project, through the experience of an Argentinean biotechnology-based nutritional supplement delivered in schools to solve child malnutrition led diseases. The paper focuses on how the case of ?Yogurito? managed to address three challenges within recent Innovation for Inclusive Development literature: (1) involving heterogeneous actors in the innovation process within knowledge intensive technologies, (2) gaining scale while fostering participatory technology development processes, and (3) promoting the articulation of STI programs with wider (social, sanitary, productive) policies. Through the trajectory of the probiotic yoghurt, the chapter examines learning and innovation strategies in technological design and institutional arrangements. We argue that the organizational strategies deployed to articulate scientific and locally grounded capacities were key elements that allowed the program?s working, its sustainability over time, and the unfolding of a regional development policy scheme.","palabras_clave":"Innovation for Inclusive Development; Biotechnology;|Local development|Knowledge intensive  technologies"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14043,"idioma_id":5,"titulo":"Impedimento por afinidad y matrimonio en el siglo XXI. Las explicaciones posibles de un adiós","resumen":"Se analiza la pérdida de sentido de los impedimentos matrimoniales ante los contornos ambiguos del matrimonio, cuyos objeto y fines no resultan claros. Los impedimentos matrimoniales suponen una proporcionalidad respecto del objeto del matrimonio y hoy día el derecho argentino no sabe qué responder a la pregunta por la naturaleza y perfil de la institución.","palabras_clave":"MATRIMONIO|INCESTO|HOMOSEXUALIDAD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14066,"idioma_id":4,"titulo":"Mortality due to  Respiratory Syncytial Virus: Burden and Risk Factors","resumen":"Rationale: Respiratory syncytial virus (RSV) is the most frequent cause of hospitalization and an important cause of death in infants in the developing world. The relative contribution of social, biologic, and clinical risk factors to RSV mortality in low-income regions is unclear.Objectives: To determine the burden and risk factors for mortality due to RSV in a low-income population of 84,840 infants.Methods: This was a prospective, population-based, cross-sectional, multicenter study conducted between 2011 and 2013. Hospitalizations and deaths due to severe lower respiratory tract illness (LRTI) were recorded during the RSV season. All-cause hospital deaths and community deaths were monitored. Risk factors for respiratory failure (RF) and mortality due to RSV were assessed using a hierarchical, logistic regression model.Measurements and Main Results: A total of 2,588 (65.5%) infants with severe LRTI were infected with RSV. A total of 157 infants (148 postneonatal) experienced RF or died with RSV. RSV LRTI accounted for 57% fatal LRTI tested for the virus. A diagnosis of sepsis (odds ratio [OR], 17.03; 95% confidence interval [CI], 13.14?21.16 for RF) (OR, 119.39; 95% CI, 50.98?273.34 for death) and pneumothorax (OR, 17.15; 95% CI, 13.07?21.01 for RF) (OR, 65.49; 95% CI, 28.90?139.17 for death) were the main determinants of poor outcomes.Conclusions: RSV was the most frequent cause of mortality in low-income postneonatal infants. RF and death due to RSV LRTI, almost exclusively associated with prematurity and cardiopulmonary diseases in industrialized countries, primarily affect term infants in a developing world environment. Poor outcomes at hospitals are frequent and associated with the cooccurrence of bacterial sepsis and clinically significant pneumothoraxes.","palabras_clave":"respiratory syncytial virus|mortality"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14079,"idioma_id":4,"titulo":"pH dependence of the voltammetric response of Polyaniline","resumen":"Voltammetric studies of Polyaniline (Pani) films were carried out in solutions of 3.7 M sulphate solutions of constant ionic strength and pH values comprised in the range between &#8722; 0.6 and 3.0. The results show that if the voltammetric results are properly corrected by capacitive currents, according to Feldberg´s model, it will be possible to obtain the potential dependence of the faradaic oxidation degree. The integrated anodic and cathodic charges are practically equal and independent of the electrolyte pH, in the range &#8722; 0.6 < pH < 2.0. The pH dependence of the current peaks is qualitatively explained by the change in the interactions between the redox centres as a consequence of the changes in their protonation.","palabras_clave":"POLYANILINE|pH|ELECTROCHEMISTRY|VOLTAMMETRY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14083,"idioma_id":4,"titulo":"Double domain wavelength multiplexed Fizeau interferometer with high resolution dynamic sensing and absolute length detection","resumen":"In this work, we present a simple photonic instrument that has the ability of measuring positions, distances and vibrations with very high resolution by means of two Fizeau interferometers (FI), both using the same optical fiber end as a probe tip itself. On the one hand we have a time domain FI powered with a 1310 nm laser and monitored by an InGaAs detector providing displacement information with resolution around a tenth of nm but regardless of the absolute position of object and of the displacement sense. On the other, a spectral domain FI version based on a super luminescent source (SLED) centred at 800 nm with bandwidth of nearly 40 nm is analysed in real time by means of a digital spectrometer. Each spectrum is acquired in a very small time interval and provides information of both length of the cavity as well as its correct sense of evolution. Resolution of this system is lower than its complementary temporal case, but distance and sense measurements are absolute and can be determined successfully by adequate processing of spectral signal. Both interferometers are optically coupled to a single fiber optic probe and are wavelength modulated. Therefore, combination of both sensors results in a new one which allows the correct knowledge of an object or surfaces under test, i.e. a high resolution of displacement data plus its absolute position and true sense of movement.","palabras_clave":"Fiber optics sensor|Fizeau interferometer|Spectral interferometer|Temporal spectrometer"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14098,"idioma_id":4,"titulo":"Robust estimators under a functional common principal components model","resumen":"When dealing with several populations of functional data, equality of the covariance operators is often assumed even when seeking for a lower-dimensional approximation to the data. Usually, if this assumption does not hold, one estimates the covariance operator of each group separately, which leads to a large number of parameters. As in the multivariate setting, this is not satisfactory since the covariance operators may exhibit some common structure, as is, for instance, the assumption of common principal directions. The existingprocedures to estimate the common directions are sensitive to atypical observations. For that reason, robust projection-pursuit estimators for the common directions under a common principal component model are considered. A numerical method to compute the first directions is also provided. Under mild conditions, consistency results are obtained. A Monte Carlo study is performed to compare the finite sample behaviour of the estimators based on robust scales and on the standard deviation. The usefulness of the proposed approach is illustrated on a real data set.","palabras_clave":"Common principal component model|Fisher-consistency|Functional data analysis|Outliers|Projection-pursuit|Robust estimation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14109,"idioma_id":4,"titulo":"Microbiological quality of honey from the Pampas Region (Argentina) throughout the extraction process","resumen":"The microbiological quality of honey obtained from different processing points and the environmental quality within honey houses were assessed in the Pampas Region (Argentina). Mold and yeast (MY), culturable heterotrophic mesophilic bacteria (CHMB), the number of sporeforming bacteria as well as the presence of Shigella spp., Salmonella spp. and fecal coliforms were evaluated in 163 samples. These samples were taken from eight honey houses. Results showed that 89 samples had &#8804;10 CFU of MY\/g honey, 69 ranged from 10 to 50 CFU\/g and two reached 65.5 CFU\/g. Eighty one percent of the samples showed &#8804;30 CFU of CHMB\/g honey and only seven samples had between 50 and 54.25 CFU\/g. Thirty six honey samples were obtained from drums: in 25 samples (69.4%) CHMB counts were less than &#8804;30 CFU\/g of honey; in 20 samples (55.5%) the values of MY were between 10 and 50 CFU\/g honey and total coliforms were only detected in 20 samples. Fecal coliforms, spores of clostridia as well as Salmonella spp. and Shigella spp were not detected and less than 50 spores of Bacillus spp. per g were observed in the honey from drums. Therefore, the microbiological honey quality within the honey houses did not show any sanitary risks. Our results were reported to honey house owners to help them understand the need to reinforce proper honey handling and sanitation practices.","palabras_clave":"HONEY|HONEY HOUSE|MICROBIOLOGICAL QUALITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14122,"idioma_id":4,"titulo":"Development of a Dissolution Test for Fenbendazole-Praziquantel Capsules Using UV-PLS Method","resumen":"A dissolution test for capsules containing 50 mg of praziquantel and 500 mg of fenbendazole was developed and validated. The optimal conditions were an USP apparatus 2 with paddles rotating at 75 rpm, 900 mL dissolution medium (a mixture of 300 mL of ethanol and 600 mL 0.5 mol L-1 HCl), at 37.0 ± 0.5 °C. Both analytes achieved with sink conditions. A published highperformance liquid chromatography (HPLC) method was used to monitoring dissolution test during the optimization. Additionally, a chemometrics method based on UV-VIS spectrophotometry and partial least-squares (PLS) was developed and validated for the simultaneous determination of both analytes in the dissolution media. The coefficients of determination were 0.9986 and 0.9959 for fenbendazole and praziquantel, respectively, and the elliptical joint confidence region (EJRC) test concluded that constant and proportional biases were absent. The optimized model was applied to build dissolution profile and its results did not show statistical differences with HPLC method.","palabras_clave":"FENBENDAZOLE|PRAZIQUANTEL|DISSOLUTION TEST|PARTIAL LEAST SQUARES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14148,"idioma_id":4,"titulo":"Robust and e\u000Ecient estimation of multivariate scatter and location","resumen":"Several&nbsp; equivariant estimators of multivariate location and scatter are studied, which are highly robust, have a controllable finite-sample efficiency and are computationally feasible in large dimensions. The most frequently employed estimators are not quite satisfactory in this respect.The Minimum Volume Ellipsoid (MVE) and the Minimum Covariance Determinant (MCD) estimators are known to have a very low efficiency. S-estimators with a monotonic weight function like the bisquare have a low efficiency when the dimension $p$ is small, and their efficiency tends to one with increasing $p$.&nbsp; Unfortunately, this advantage is outweighed by a serious loss in robustness for large $p$.&nbsp; Four families of estimators with controllableefficiencies whose performance for moderate to large $p$ has not been explored to date are studied: S-estimators with a non-monotonic weight function, MM-estimators, $au $-estimators, and the Stahel-Donoho estimator. Two types of starting estimators are employed: the MVE computed through subsampling, and a semi-deterministic procedure previously proposed for outlier detection,&nbsp; based on the projections with maximum and minimumkurtosis.&nbsp; A simulation study shows that an S-estimator with non-monotonic weight function can simultaneously attain high efficiency and high robustness for $pgeq 15$, while an MM-estimator with a particular weight function can be recommended for $p&lt;15$. For both recommended estimators, the initial values are given by the semi-deterministic procedure mentioned above.","palabras_clave":"MM-estimator|\u001C Tau-estimator|S-estimator|Stahel-Donoho Estimator"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14160,"idioma_id":4,"titulo":"Prenatal ethanol exposure modifies locomotor activity and induces selective changes in Met-enk expression in adolescent rats","resumen":"Several studies suggest that prenatal ethanol exposure (PEE) facilitates ethanol intake. Opioid peptides play a main role in ethanol reinforcement during infancy and adulthood. However, PEE effects upon motor responsiveness elicited by an ethanol challenge and the participation of opioids in these actions remain to be understood. This work assessed the susceptibility of adolescent rats to prenatal and\/or postnatal ethanol exposure in terms of behavioral responses, as well as alcohol effects on Met-enk expression in brain areas related to drug reinforcement. Motor parameters (horizontal locomotion, rearings andstereotyped behaviors) in pre- and postnatally ethanol-challenged adolescents were evaluated. Pregnant rats received ethanol (2 g\/kg) or water during gestational days 17-20. Adolescents at postnatal day 30 (PD30) were tested in a three-trial activity paradigm (habituation, vehicle and drug sessions). Met-enk content was quantitated by radioimmunoassay in several regions: ventral tegmental area [VTA], nucleus accumbens[NAcc], prefrontal cortex [PFC], substantia nigra [SN], caudate-putamen [CP], amygdala, hypothalamus and hippocampus. PEE significantly reduced rearing responses. Ethanol challenge at PD30 decreased horizontal locomotion and showed a tendency to reduce rearings and stereotyped behaviors. PEE increased Met-enk content in the PFC, CP, hypothalamus and hippocampus, but did not alter peptide levels in the amygdala, VTA and NAcc. These findings suggest that PEE selectively modifies behavioral parameters at PD30 and induces specific changes in Met-enk content in regions of the mesocortical and nigrostriatal pathways, the hypothalamus and hippocampus. Prenatal and postnatal ethanol actions on motor activity in adolescents could involve activation of specific neuralenkephalinergic pathways.","palabras_clave":"Ethanol-induced locomotor activity|Ontogeny|Adolescence|Enkephalins|Opioid peptides"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14161,"idioma_id":4,"titulo":"Context-dependent extinction of an appetitive operant conditioned response in infant rats","resumen":"The present study evaluated context-dependent learning under an operant conditioning procedure in infant rats. Preweanling rats were trained in context A during postnatal days (PDs) 16 and 17 to learn an appetitive operant conditioning task, employing milk chocolate as appetitive reinforcer. On PD18 the operant response was extinguished in context A, or in an alternative context B. The change from context A to B between acquisition and extinction did not affect the number of responses during extinction, but slightly modified the shape of the extinction curve. On PD19, a renewal test conducted in context A clearly showed ABA-renewal of the extinguished operant response. These results add to the body of evidence indicating that infants are able to acquire and retain contextual information, and support the notion that extinction during this ontogenetic period involves new learning.","palabras_clave":"INFANT RAT|CONTEXT|OPERANT CONDITIONING|EXTINCTION|RENEWAL EFFECT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14184,"idioma_id":4,"titulo":"Mice lacking sialyltransferase ST3Gal-II develop late onset obesity and insulin resistance","resumen":"Sialyltransferases are a family of 20 gene products in mice and humans that transfer sialic acid from its activated precursor, CMP-sialic acid, to the terminus of glycoprotein and glycolipid acceptors. ST3Gal-II (coded by the St3gal2 gene) transfers sialic acid preferentially to the three positions of galactose on the Gal&#946;1-3GalNAc terminus of gangliosides GM1 and GD1b to synthesize GD1a and GT1b, respectively. Mice with a targeted disruption of St3gal2 unexpectedly displayed lateonset obesity and insulin resistance. At 3 months of age, St3gal2-null mice were the same weight as their wild type (WT) counterparts, but by 13 months on standard chow they were visibly obese, 22% heavier and with 37% greater fat\/lean ratio than WT mice. St3gal2-null mice became hyperglycemic and displayed impaired glucose tolerance by 9 months of age. They had sharply reduced insulin responsiveness despite equivalent pancreatic islet morphology. Analyses of insulin receptor (IR) tyrosine kinase substrate IRS-1 and downstream target Akt revealed decreased insulininduced phosphorylation in adipose tissue but not liver or skeletal muscle of St3gal2-null mice. Thin-layer chromatography and mass spectrometry revealed altered ganglioside profiles in the adipose tissue of St3gal2-null mice compared to WT littermates. Metabolically, St3gal2-null mice display a reduced respiratory exchange ratio compared to WT mice, indicating a preference for lipid oxidation as an energy source. Despite their altered metabolism, St3gal2-null mice were hyperactive. We conclude that altered ganglioside expression in adipose tissue results in diminished IR sensitivity and late-onset obesity.","palabras_clave":"ganglioside |ST3-gal II|obesity|insulin resistance"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14198,"idioma_id":4,"titulo":"Market and Policy in Argentina: When business needs from Social Sciences. Exploring the non- market strategies and government in a hybrid regime","resumen":"The Market has to deal with more demanding customers and regulatory policies. The non- market environment become is more important for business. The managers must dedicate time to understand the non- market environment. This research seeks to know and to understand the relationship between the Market and the Politics related to the non-market strategies of companies in Argentina. The hypothesis of this work argues that the companies in Argentina do not understand how to approach the political decisions of the State with hybrid political regimes in matters that are incumbent upon them.Companies focus on market logic without understanding the logic of 'non-market' environments that we will call Complex State-Actors \/ Social Consumers. It is assumed that there are concepts and tools of the social sciences, such as governance and non-market governance, that allow to understand this situation to improve the profitability of the business in political systems with hybrid regime like Argentina.","palabras_clave":"Market|Politics|Argentina|Business"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14199,"idioma_id":5,"titulo":"'Desarrollos' fallidos en la minería histórica. Famatina y Capillitas, apuntes para pensar el presente socioambiental.","resumen":"Este trabajo aborda las condiciones laborales y las consecuencias socioambientales de la gran minería en La Rioja y Catamarca, Argentina, entre 1850 y 1914, analizando el devenir de los dos mayores yacimientos explotados por aquellos momentos en el país: Famatina y Capillitas. Afirmamos que la apropiación, por parte de las empresas, del plusvalor de los trabajadores, y la explotación de recursos naturales, influyeron en las crisis de esta minería histórica, que llevaron a abandonar la explotación de esos yacimientos metalíferos durante décadas, e incluso, dejar de lado la estrategia económica basada en la minería a gran escala; que parecía ser, en un primer momento -para la elite gobernante-, una solución a los problemas de la región. Si bien las explicaciones más destacadas acerca del fracaso  de estas experiencias mineras fue la relación costo-beneficio desventajosa de la actividad y el difícil acceso a los transportes, sumado a desfavorables contextos económicos y políticos nacionales y mundiales, otras causas y consecuencias socioambientales, sobre las que aquí avanzamos, no habían sido suficientemente trabajadas.Recurrimos al análisis crítico de fuentes documentales, desde perspectivas y metodologías propias de la historia ambiental, la sociología y la ecología política. Esperamos aportar claves para comprender las contradicciones de nuestro tiempo, en momentos en que se discute la explotación minera sobre los mismos territorios y yacimientos.","palabras_clave":"MINERÍA|DESARROLLO REGIONAL|ECOLOGÍA POLITICA|TRABAJADORES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14200,"idioma_id":4,"titulo":"Weak lensing measurement of the mass-richness relation using the SDSS database","resumen":"We study the mass?richness relation using galaxy catalogues and images from the Sloan Digital Sky Survey. We use two independent methods: In the first one, we calibrate the scaling relation with weak-lensing mass estimates. In the second procedure, we apply a background subtractiontechnique to derive the probability distribution, P(M|N), that groups with N-members have a virialized halo mass M. Lensing masses are derived in different richness bins for two galaxy systems sets: the maxBCG catalogue and a catalogue based on a group finder algorithm developed by Yang et al. Results of maxBCG are used to test the lensing methodology. Thelensing mass?richness relation for the Yang et al. group sample shows a good agreement with P(M|N) obtained independently with a straightforward procedure.","palabras_clave":"gravitational lensing: weak|dark matter|halo occupation distribution"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14212,"idioma_id":4,"titulo":"Displacement of native Patagonian freshwater silverside populations (Odontesthes hatcheri, Atherinopsidae) by introgressive hybridization with introduced O. bonariensis.","resumen":"The Patagonian silverside Odontesthes hatcheri is a native fish restricted to streams and lakes of Patagonia (Argentina and Chile). Stocking programs to enhance recreational fisheries in man-made reservoirs have introduced a nonnative, closely-related species (the pejerrey O. bonariensis) in Patagonia almost a century ago, and yet little is known about the invasiveness of this species. To evaluate the impact of these introductions we analyze genetic data (microsatellite markers and mitochondrial DNA) to quantify the incidence of hybridization between these two species and assess potential effects on native population structure. Phylogeographic analyses reveal weak geographic differentiation among populations of O. hatcheri, in agreement with previous studies for other freshwater fishes in Patagonia strongly influenced by Quaternary glaciations and hydrographic basin changes since the last glaciation. However, many populations have unique genetic pools. In several areas, introductions resulted in extensive hybridization, with high frequencies of F2 and backcrossed hybrids in natural populations, and in some cases O. bonariensis has completely displaced the native populations. The negative impact of these introductions on native populations is correlated to temperature, a critical parameter in the face of global warming, suggesting that invasiveness of O. bonariensis may increase in the future. Our results advise against continuing stocking programs to preserve the integrity of natural populations of the Patagonian silverside.","palabras_clave":"Invasive species|Microsatellite markers|Mitochondrial DNA|Stocking|Global warming|Pejerrey"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14215,"idioma_id":4,"titulo":"A new Encephalarteae trunk (Cycadales) from the Cretaceous of Patagonia (Mata Amarilla Formation, Austral Basin), Argentina","resumen":"The cycads are remnants of a flora that dominated the ecosystems across Mesozoic. However, floristic and climate changes from Cretaceous to Paleogene (e.g. diversification of the Magnoliophyta, temperature diminution, etc.) constrained the cycad populations. This scenario is documented by the fossil record, showing a peak of diversity in the Cretaceous of Patagonia with several taxa of trunks, leaves and reproductive structures. On the other hand, the fossil stem record of cycads is scanty, with seventeen genera described around the world. Eight come from Argentina (Triassic to Paleogene strata), and six of them come from Cretaceous of Patagonia. In this research, we erect a new genus of fossil cycad come from Upper Cretaceous of Austral Basin, Patagonia (Argentina). The good preservation of the permineralized stem allows profuse descriptions and comparisons, allows assigning the Zamunercycas nov gen. to the Encephalarteae. This new taxa has a great development of parenchyma tissues with a marked amount of specialized cells (idioblasts), probably related with some protection function. The probable climatic conditions of the Mata Amarilla Formation were inferred, from the new genus described, and correlated with hot and humid to xeric climate the southern of South America during the early Upper Cretaceous. Zamunercycas reinforce the existence of a greater diversity of Encephalarteae in South America during the mid-Cretaceous.","palabras_clave":"anatomy|argentina|cycadales|patagonia"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14227,"idioma_id":4,"titulo":"The HUGE formula (hematocrit, urea, gender) for screening for chronic kidney disease in elderly patients: a study of diagnostic accuracy","resumen":"Chronically reduced glomerular filtration rate (GFR) in old people does not always mean that they suffer from chronic kidney disease (CKD) since their GFR can just be reduced by aging. The HUGE equation has been recently described and validated in Spain for screening CKD without taking into account the patient?s GFR value. This equation is based on patient?s hematocrit, plasma urea levels and gender. The present study documented that the HUGE equation had and acceptable performance for screening CKD in elderly Argentine patients.","palabras_clave":"Elderly|HUGE equation|Chronic kidney disease"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14261,"idioma_id":4,"titulo":"Induction of Both Local Immune Response in Mice and Protection in a Rabbit Model by Intranasal Immunization with Modified Vaccinia Ankara Virus Expressing a Secreted Form of Bovine Herpesvirus 1 Glycoprotein D","resumen":"In this study, we evaluated the immunogenicity and efficacy of mucosal delivery of a recombinant modified vaccinia Ankara virus (MVA) expressing the secreted version of bovine herpesvirus type 1 (BoHV-1) glycoprotein D (MVA-gDs) without addition of adjuvant in two animal models. First, we demonstrated the capability of MVA-gDs of inducing both local and systemic anti-gD humoral immune response after intranasal immunization of mice. Then, we confirmed that two doses of MVA-gDs administered intranasally to rabbits induced systemic anti-gD antibodies and conferred protection against BoHV-1 challenge. Our results show the potential of using MVA as a vector for the rational design of veterinary vaccines capable of inducing specific and protective immune responses both at local and systemic level","palabras_clave":"veterinary|vaccines|vectors"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14266,"idioma_id":4,"titulo":"Structure of compact stars in R-squared Palatini gravity","resumen":"We analyse configurations of neutron stars in the so-called R-squared gravity in the Palatini formalism. Using a realistic equation of state we show that the mass-radius configurations are lighter than their counterparts in General Relativity. We also obtain the internal profiles, which run in strong correlation with the derivatives of the equation of state, leading to regions where the mass parameter decreases with the radial coordinate in a counter-intuitive way. In order to analyse such correlation, we introduce a parametrisation of the equation of state given by multiple polytropes, which allows us to explicitly control its derivatives. We show that, even in a limiting case where hard phase transitions in matter are allowed, the internal profile of the mass parameter still presents strange features and the calculated mass-radius configurations also yield neutron stars lighter than those obtained in General Relativity.","palabras_clave":"modified gravity|neutron stars|Palatini formalism"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14312,"idioma_id":5,"titulo":"Desigualdades en salud en la norpatagonia argentina: una aproximación desde el enfoque de las capacidades","resumen":"En los últimos años ha aumentado la cantidad de estudios orientados a indagar acerca de la relación entre desigualdades sociales y salud. Si bien América Latina es el continente con mayores asimetrías en la distribución de ingresos, esto no se correlaciona con el desarrollo de esfuerzos intelectuales dirigidos a analizar el impacto de las desigualdades socioeconómicas en los procesos de salud\/enfermedad\/atención\/cuidado (PSEAC).En función de ello, en el presente trabajo nos propusimos analizar desigualdades en la salud a la luz del enfoque de las capacidades seniano, prestando especial atención a los funcionamientos logrados en salud y a las prácticas alimentarias,de actividad física en poblaciones de contextos socioeconómica y culturalmente diferentes. Para ellos tomamos como evidencia empírica un relevamiento realizado en la ciudad de San Carlos de Bariloche, Río Negro, norpatagonia argentina","palabras_clave":"Desigualdades|Salud|Capacidades"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14327,"idioma_id":5,"titulo":"Hacia la identificación de dimensiones relevantes relacionadas con el aprendizaje organizacional","resumen":"En este trabajo se realiza una revisión delos instrumentos utilizados para indagar sobre elaprendizaje organizacional, a fin de proponer unaguía de relevamiento. En el campo del diagnósticodel aprendizaje organizacional prima la investigacióna partir de escalas que dan cuenta de la opinión delos informantes sobre las dimensiones en las quese operacionaliza el aprendizaje organizacional,en tanto que son mucho menos frecuentes losabordajes cualitativos que intentan, a partir de unproceso inductivo, abordar el tema con la miradade los actores. Partiendo de la identificación de lasdimensiones consideradas y su operacionalización,así como de las técnicas puestas en juego para llevaradelante el relevamiento de la información, serealiza una propuesta de preguntas de investigaciónorientadas a identificar los procesos, obstáculos,facilitadores e impactos originados en los procesos deaprendizaje organizacional, como espacios en los quese recupera e incorpora en las rutinas organizacionalesla experiencia adquirida en la resolución de losproblemas que se enfrentan","palabras_clave":"DIMESNSIONES DEL APRENDIZAJE ORGANIZACIONAL|FACILITADORES|OBSTÁCULOS|INSTRUMENTOS DE RELEVAMIENTO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14350,"idioma_id":5,"titulo":"Conservación utilización y acceso a recursos fitogenéticos de importancia para la agricultura y la alimentación.","resumen":"La Argentina posee una importante riqueza de plantas nativas y es centro deorigen y diversidad de importantes cultivos. La diversidad genética de especies vegetales de importancia para la agricultura y la alimentación, es conservada en el marco de distintas iniciativas, destacándose la Red de Recursos Fitogenéticos del INTA. El objetivo es conservar y utilizar especies en forma sustentable para distintas regiones agroecológicas del territorio nacional. La biotecnología y la informática son utilizadas en el manejo de los recursos genéticos;se emplean para la conservación, evaluación y uso de las especies conservadas en la Red. Se presentan las iniciativas existentes referidas a la protección legal de los recursos fitogenéticos.","palabras_clave":"."},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14353,"idioma_id":5,"titulo":"Los 'Cuadernos Médico Sociales' de Rosario y las revistas de la Medicina Social Latinoamericana entre las décadas de 1970 y 1980","resumen":"Entre 1970 y 1980, un conjunto de revistas fueron creadas con el objetivo de difundir las ideas de la Medicina Social latinoamericana en distintos países del continente, en una etapa temprana en la institucionalización de este movimiento que luego se afianzó en Brasil bajo el nombre de ?Salud Colectiva?. En este trabajo recorremos las principales características de esos emprendimientos: la ?Revista Centroamericana de Ciencias de la Salud?, ?Saúde em Debate?, ?Salud Problema?, ?Revista Latinoamericana de Salud? y ?Cuadernos Médico Sociales?. En particular, nos focalizamos en los Cuadernos Médico Sociales de Rosario, analizando las condiciones de su surgimiento y los procesos editoriales que marcaron esta publicación, donde fue central la figura de Carlos Bloch como editor e ideólogo de la revista.","palabras_clave":"Medicina Social Latinoamericana, |Revistas, |Salud Pública, |Ciencias  Sociales"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14365,"idioma_id":4,"titulo":"The carry-over effects of pollen shortage decrease the survival of honeybee colonies in farmlands","resumen":"1. Many studies have reported honeybee colony losses in human-dominated landscapes.While bee floral food resources have been drastically reduced over past decades in human dominated landscapes, no field study has yet been undertaken to determine whether there is a carry-over effect between seasonal disruption in floral resource availability and high colony losses.2. We investigated if a decline in the harvest of pollen by honeybees in spring affected managed honeybee colony dynamics (brood size, adult population and honey reserves) and health (Varroa mite loads and colony survival) throughout the beekeeping season.3. A decline in pollen harvest was associated with a direct reduction in brood production,leading to a negative effect on the adult population size later in the season, and lower honeyreserves before the onset of winter. Furthermore, the decline in pollen harvest negativelyimpacted the health of the colony, resulting in higher Varroa mite loads and higher seasonaland winter colony losses.4. Early-warning signs of these carry-over effects were identified, showing that preferentialinvestment in honey reserves instead of brood production early in the season increased thedecline in pollen harvest and its associated carry-over effects.5. Synthesis and applications. The results suggest that the decline in pollen harvest may havebeen overlooked as a cause of pollen shortage and associated bee colony losses. Strategies toavoid such losses in intensive farmland systems include (i) limiting or avoiding honey harvests in spring, (ii) monitoring colonies for early-warning signals of colony failure and (iii) increasing the amount of floral resources available through wise land-use management.","palabras_clave":"agricultural landscapes|floral resource scarcity|honeybee colony losses|life-history strategy"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14366,"idioma_id":4,"titulo":"Predictive systems models can help elucidate bee declines driven by multiple combined stressors","resumen":"Bee declines are driven by multiple combined stresses, making it exceedingly difficult to identify experimentally the most critical threats to bees and their pollination services.We highlight here the too often ignored potential of mechanistic models in identifying critical stress combinations. Advanced bee models are now available as open access tools and offer an unprecedented opportunity for bee biologists to explore bee resilience tipping points in a variety of environmental contexts.We provide general guidelines on how to run beemodels to help detect a priori critical stress combinations to be targeted in the field. This so-called funnel analysis should be performed in tight conjunction with the recent development of large-scale field monitoring programs for bee health surveillance.","palabras_clave":"field monitoring program|mechanistic modeling|agent-based models|Apis mellifera"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14388,"idioma_id":4,"titulo":"Predictive outcomes for HER2-enriched cancer using growth and metastasis signatures driven by SPARC","resumen":"Understanding the mechanism of metastatic dissemination is crucial for the rational design of novel therapeutics. The secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein which has been extensively associated with human breast cancer aggressiveness although the underlying mechanisms are still unclear. Here, shRNA-mediated SPARC knockdown greatly reduced primary tumor growth and completely abolished lung colonization of murine 4T1 and LM3 breast malignant cells implanted in syngeneic BALB\/c mice. A comprehensive study including global transcriptomic analysis followed by biological validations confirmed that SPARC induces primary tumor growth by enhancing cell cycle and by promoting a COX-2-mediated expansion of myeloid-derived suppressor cells (MDSC). The role of SPARC in metastasis involved a COX-2-independent enhancement of cell disengagement from the primary tumor and adherence to the lungs that fostered metastasis implantation. Interestingly, SPARC-driven gene expression signatures obtained from these murine models predicted the clinical outcome of patients with HER2-enriched breast cancer subtypes. In total, the results reveal that SPARC and its downstream effectors are attractive targets for antimetastatic therapies in breast cancer. Implications: These findings shed light on the prometastatic role of SPARC, a key protein expressed by breast cancer cells and surrounding stroma, with important consequences for disease outcome.","palabras_clave":"her2|breast cener|sparc"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14412,"idioma_id":4,"titulo":"Local Texture Descriptors for the Assessment of Differences in Diffusion Magnetic Resonance Imaging of the Brain","resumen":"Purpose: Descriptors extracted from magnetic resonance imaging (MRI)of the brain can be employed to locate and characterize a wide range of pathologies. Scalar measures are typically derived within a single voxel unit, but neighborhood-based texture measures can also be applied. In this work we propose a new set of descriptors to compute local texture characteristics from scalar measures of diffusion tensor imaging (DTI), such as mean and radial diffusivity, and fractional anisotropy.Methods: We employ weighted rotational invariant local operators, namely standard deviation, inter-quartile range, coefficient of variation, quartile coefficient of variation, and skewness. Sensitivity and specificity of those texture descriptors were analyzed with tract-based spatial statistics of the white matter on a diffusion MRI group study of elderly healthy controls (HC), patients with mild cognitive impairment (MCI), and mild or moderate Alzheimer´s disease (AD). In addition, robustness against noise has been assessed with a realistic diffusion weighted imaging phantom and the contamination of the local neighborhood with gray matter has been measured.Results: The new texture operators showed an increased ability for finding formerly undetected differences between groups compared to conventional DTI methods. In particular, the coefficient of variation, quartile coefficient of variation, standard deviation and inter-quartile range of the mean and radial diffusivity detected significant differences even between previously not significantly discernible groups, such as MCI vs. moderate AD and mild vs. moderate AD. The analysis provided evidence of low contamination of the local neighborhood with gray matter and high robustness against noise.Conclusions: The local operators applied here enhance the identification and localization of areas of the brain, where cognitive impairment takes place, and thus indicate them as promising extensions in diffusion MRI group studies.","palabras_clave":"local texture |white matter|Alzheimer's disease|diffusion tensor imaging"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14413,"idioma_id":4,"titulo":"Automatic ear detection and feature extraction using Geometric Morphometrics and Convolutional Neural Networks","resumen":"Accurate gathering of phenotypic information is a key aspect in several subject matters, including biometric identification, biomedical analysis, forensics, and many other.Automatic identification of anatomical structures of biometric interest, such as fingerprints, iris patterns, or facial traits, are extensively used in applications like access control, anthropological research, and surveillance, all having in common the drawback of requiring intrusive means for acquiring the required information.In this regard, the ear structure has multiple advantages.Not only the ear´s biometric markers can be easily captured from the distance with non intrusive methods, but also they experiment almost no changes over time, and are not influenced by facial expressions.However, the most relevant proposals in the literature for automated ear detection do not take advantage of its phenotypic attributes that biologically determine the ear´s shape and form.Therefore, these methods require acquisition in controlled conditions to perform adequately.In this paper we present a new method, based on two well established methodologies, Geometric Morphometrics and Deep Learning algorithms, for automatic ear detection and feature extraction in the form of 2D landmarks.A convolutional neural network was trained with a set of manually landmarked examples.The trained network is able to provide morphometric landmarks on ears´ images automatically, with a performance that matches human assisted landmarking.The ability to perform in the open ({em i.e.}, in images or video taken with no specific acquisition preparation), together with the feasibility of using ear landmarks as feature vectors for people identification, opens a novel spectrum of biometrics applications.","palabras_clave":"."},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14415,"idioma_id":4,"titulo":"Improvement of copper stress tolerance in pepper plants (Capsicum annuum L.) by inoculation with arbuscular mycorrhizal fungi","resumen":"Improvement of copper stress tolerance in pepper plants (Capsicum annuum L.) by inoculation with arbuscular mycorrhizal fungi?Authors?Marcela Ruscitti?María Arango?José Beltrano?AbstractThe effect of arbuscular mycorrhizal fungi (AMF) inoculation, on pepper plant growth and physiological parameters in response to increasing soil Cu concentrations was studied. Treatments consisted of inoculation or not with Funneliformis mosseae or Rhizophagus intraradices and the addition of Cu to soil at concentrations of 0, 2, 4 and 8 mM CuSO4. The increase in copper concentration diminished the inoculation in all treatments. The highest experimental concentration of Cu (8 mM) reduced significantly the hyphae viability and ALP activity, regardless of the inocula used. The total dry weight and the leaf area were higher for mycorrhizal plants. The mycorrhizal dependence was 30 and 50% for plants inoculated with F. mosseae and R. intraradices, respectively at 8 mM CuSO4. The electrolyte leakage was higher at higher Cu concentrations, in roots and leaves. Net photosynthetic rates and transpiration were lower in plants treated with Cu, regardless of the inocula. At low Cu concentration in soil no differences were observed in Cu content in the shoots and roots. At 4 mM Cu, Cu content in roots was significantly higher than in shoots. At 8 mM Cu, in non-inoculated plants accumulate more Cu than inoculated plants in the roots, leaves and fruits regardless of the inocula. Beneficial microbial inoculants such as AMF, is an attractive strategy to farmers in the context of sustainable agriculture. Pre-inoculation in transplants could be an adequate practice to alleviate the deleterious effects in stress of pepper plants. However different AMF species can differ in their ability to minimize stress effects and promote plant growth.KeywordsCapsicum annuum Copper stress Arbuscular mycorrhiza Funneliformis mosseae Rhizophagus intraradices Heavy metals","palabras_clave":"CAPSICUM ANNUUM|COPPER STRESS|ARBUSCULAR MYCORRHIZAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14427,"idioma_id":5,"titulo":"La materialidad de los jardines de infantes como productora de experiencias: usos de la diversidad y relaciones de desigualdad","resumen":"Este artículo presenta resultados preliminares de una investigación socioantropológica realizada  en escuelas de nivel inicial de la Ciudad de Buenos Aires. Pone el foco en los usos de la diversidad sociocultural\/desigualdad y su vinculación de con la materialidad en que transcurre la vida cotidiana de las instituciones en las que realizamos el trabajo de campo. Se describe analíticamente una situación social -la visita de un funcionario a uno de los jardines de infantes bajo estudio- en la que los actores institucionales tematizan y producen los espacios en que desarrollan sus prácticas, disputando sus lugares y poniendo en tensión las relaciones de diversidad\/desigualdad que caracterizan sus interacciones. Posteriormente, a partir de la consideración de un distrito escolar en toda su extensión, se  analizan las características de la ?oferta educativa? del nivel inicial, la incorporación de teléfonos celulares en el ámbito de los jardines como modo de sostener la tarea docente, y los inicios de la informatización en la inscripción escolar. A partir de estas cuestiones, se va iluminando la historia reciente del nivel inicial en la Argentina, así como aspectos de las experiencias de sus docentes. El artículo sostiene que el abordaje de la materialidad constituye un indicio del procesamiento actual de relaciones de diversidad\/desigualdad.","palabras_clave":"TRABAJO DOCENTE|DIVERSIDAD\/DESIGUALDAD|MATERIALIDAD|NIVEL INICIAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14439,"idioma_id":5,"titulo":"La activacion de un patrimonio natural en Norpatagonia Argentina","resumen":"En este artículo se analizan aspectos relativos a la creación de las áreas protegidas en Argentina, en ligazón con el proceso de construcción del Estado y de consolidación de la Nación en Norpatagonia. Recuperamos la figura de Francisco Moreno y de Exequiel Bustillo, dos personajes clave en la creación de las mismas y en la impronta simbólica y estética otorgada a la Patagonia argentina. Se sostiene que a partir de sus trayectorias, vinculaciones políticas y propuestas se sentaron las bases del ideario fundacional de los Parques Nacionales, las cuales destacaban el rol de la naturaleza como inspiradora de los valores de la patria. Asimismo, se utiliza la categoría de analítica de ?activación patrimonial? con el objeto de ahondar en el interrogante acerca de por qué ciertos espacios naturales son valorados como patrimonio del conjunto de la nación y por ende deben ser preservados. Los resultados que aquí se presentan provienen del trabajo con fuentes documentales y de entrevistas en profundidad, en el marco de una investigación en el Departamento Los Lagos, provincia de Neuquén, Argentina, territorio que integra el Parque Nacional Nahuel Huapi.","palabras_clave":"Estado|Activacion patrimonial|Territorio|Naturaleza"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14458,"idioma_id":4,"titulo":"Allele mining in the Argentine public maize inbred line collection of two paralogous genes encoding NAC domains","resumen":"NAC proteins are plant transcription factors involved in biotic and abiotic stress responses, with conserved sub-domain motifs. To our knowledge, no diversity studies have been carried out at the nucleotide level of candidate NAC genes of crops. Here, we investigated allele diversity and putative protein-coding sequences in two paralogous maize NAC genes, GRMZM2G179885 and GRMZM2G347043. The GRMZM2G179885 gene is the closest ortholog of WNAC-B1, responsible for enhancing nitrogen remobilization and senescence in wheat. The GRMZM2G347043 gene is the homolog to the characterized ZmSNAC1 allele, which promotes the dehydration tolerance response in Arabidopsis. Nucleotide diversity for both genes was determined in a core set of the Argentine public maize collection of temperate inbred lines structured in four diverse subpopulations. The frequency of nucleotide changes at both exons and introns of GRMZM2G179885 and GRMZM2G347043 was lower (1\/137 bp-1\/83 bp and 1\/472 bp-1\/51 bp, respectively) than that of other maize genes. Tajima?s D values were non-significant, indicating the absence of selection at these genes. The five sub-domains of NAC proteins were predicted at both genes, thus implying: (i) high conservation of these two genes at the genomic level, and (ii) scarce divergence between GRMZM2G179885 and GRMZM2G347043 protein-coding sequences, which confirms their relationships as ancestral paralogs. Although the functional activity of both genes in maize metabolism is still unclear, our findings contribute to demonstrating that their NAC proteins are common alleles and would serve as a source for abiotic stress improvement in the Argentine public maize inbred line collection.","palabras_clave":"ZmSNAC1|WNAC-B1|Orthologous|Paralogous|Population diversity|Synteny|Domain conservation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14485,"idioma_id":5,"titulo":"Desde la distancia hacia los cercanos establecimientos de producción lechera","resumen":"Desde la distancia hacia los cercanos establecimientos de producción lechera Sebastián, Recce, Carina, Boggero; Omar, Zoratti(Facultad de Ciencias Veterinarias. Universidad Nacional del Litoral)ArgentinaMagister. Veterinario. Sebastián, RecceMagister. Veterinario. Docente de Grado de la Facultad de Ciencias Veterinarias (FCV) de la Universidad Nacional del Litoral (UNL) de la asignatura Genética Veterinaria. Cargo: Jefe de Trabajos Prácticos. Concursado. Dedicación Exclusiva. Coordinador de la Tecnicatura de Pregrado en Producción Primaria de Leche (FCV.UNL) dictada desde la modalidad a distancia. Docente de las Tecnicaturas Producción Primaria de Leche y Alimentación del Ganado Vacuno (FCV.UNL). Director de un Proyecto de Extensión de Interés Social de la Secretaría de Extensión de la UNL. Director de Cursos de Capacitación para personas relacionadas a la producción primaria de leche. Doctorando en Ciencias Veterinarias. Año de ingreso: 2016. Director de la Cientibecaria: Salazar, Macarena; cuyo título es ?Determinaciones serológicas de Brucelosis y Toxoplasmosis en cabras en sistemas de subsistencia en áreas rurales  del norte Santafesino?. Período 2016-2017. Participación en el Proyecto CAI+D 2011. Código: 50120110100045LI. Resol. CS 245\/13. ?Evaluación de la adaptabilidad al medio y calidad de la carne de tres razas caprinas y sus cruzamientos en explotaciones de pequeños productores del norte santafesino?. Período 2013-2016. Función: Grupo Colaborador.Correspondencia: srecce@fcv.unl.edu.arMagister. Veterinaria. Carina, BoggeroMagister. Veterinaria. Docente de grado de la Facultad de Ciencias Veterinarias de la Universidad Nacional del Litoral. Asignatura: Producción de Pequeños Rumiantes. Producción animal II. Cargo: Jefe de trabajos Prácticos. Dedicación Exclusiva. Docente de posgrado. Facultad de Ciencias Veterinarias y Facultad de Ingeniería Química Universidad Nacional del Litoral en la Especialidad en Ciencia y Tecnología de Productos lácteos. Coordinadora de la Tecnicatura en Alimentación del Ganado Vacuno, modalidad a distancia. Docente de la Tecnicatura en Producción Primaria de Leche y Tecnicatura en Administración agropecuaria (Facultad de Ciencias Agrarias). Directora de un proyecto de Extensión de interés social de la UNL. Coordinadora de la Mención Producción de Rodeos Lecheros de la Maestría en Ciencias Veterinarias. Res. ?C.D.? nº 177.abpg. Investigadora del Proyecto de Investigación y Desarrollo CAI+D denominado ?Competencias sociales en la formación universitaria como objetivo educativo?. Investigadora del Proyecto de Investigación y Desarrollo CAI+D denominado: ?Evaluación de la adaptabilidad de carne de tres razas caprinas y sus cruzamientos en la explotación de pequeños productores del norte santafesino. Investigadora del Proyecto de Investigación y Desarrollo CAI+D denominado: ?Estrés térmico, su impacto en la producción de leche y bienestar animal?. Evaluadora de distintos trabajos de tesis de Maestría y Especialidad de Buiatría.Correspondencia: cboggero@fcv.unl.edu.arIngeniero Agrónomo. Omar ZorattiIngeniero Agrónomo. Profesor para la Enseñanza Media y Superior en Ciencias Agropecuarias, Especialidad Ingeniería Agronómica. Especialista en Docencia Universitaria. Profesor Asociado, concursado, dedicación Exclusiva A, a cargo de la asignatura Producción Animal II de la carrera de Medicina Veterinaria de la Facultad de Ciencias Veterinarias (FCV) de la Universidad Nacional del Litoral (UNL). Responsable de las asignaturas Electivas y Optativas Producción Apícola, Producción Caprina y Acuicultura. Director de Pregrado y Educación a Distancia de la FCV.UNL. Director y Docente de la Tecnicatura en Alimentación de Ganado Vacuno. Consejero del Personal Académico Claustro Profesores Titulares y Asociados. Código: 201101 00026 LI. Integrante del equipo de investigadores en el Proyecto CAI+D 2011 ?Evaluación de la adaptabilidad al medio y calidad de la carne de 3 razas caprinas y sus cruzamientos en explotaciones de pequeños productores del norte santafesino?. Código: 201101 00045 LI. Integrante del equipo de investigadores del Proyecto INTA-AUDES-CONADEV: CIAC-940141 ?Evaluación de factores que mejoren la productividad de forraje en ambientes salinos de la Provincia de santa Fe?. Integrante del Proyecto de Extensión de Interés Social (PEIS) ?Prevención en zoonosis  y capacitación en sistemas de producción caprina en el Departamento Paraná (Entre RíosCorrespondencia: ozoratti@fcv.unl.edu.ar?Desde la distancia hacia los cercanos establecimientos de producción lechera ResumenLa Facultad de Ciencias Veterinarias, junto con la Facultad de Ciencias Agrarias de la UNL, teniendo presente sus funciones sustantivas (Enseñanza-Investigación-Extensión) y adecuándose a los cambios en el medio donde se inserta, diseña la propuesta de pregrado Tecnicatura en Producción Primaria de Leche. La misma nace de una demanda concreta de egresados de la carrera de Medicina Veterinaria, solicitando una propuesta para la capacitación integral de tamberos. Dicha oferta educativa, destinada al personal de campo y recordando que pensar en la educación es poder pensar en instancias formativas integrales, se delinea conociendo el perfil de los destinatarios. Desde la virtualidad se ha brindado una oferta de formación para personas que por diversas situaciones no podrían alcanzar dichos conocimientos de una manera formal. Se destaca la importancia de la educación a distancia como recurso para la inclusión de alumnos al sistema educativo. También la adquisición de conocimientos de los alumnos y egresados que le permiten ascender en sus puestos laborales ya disponibles y\/o conseguir empleos. Por último, la importancia de la UNL en dar respuestas a demandas concretas del medio donde se inserta para favorecer el crecimiento de la región a través de la excelente formación de recursos humanos.Palabras Claves:Alumnos, aprendizaje, enseñanza, tamberos, tecnicatura, universidad, virtualidadAbstract      The Faculty of Veterinary Sciences, together with the Faculty of agricultural sciences of the UNL, tearing in mind its substantive functions (Teaching-Investigation-Extension) and adapting to changes in the environment where it is inserted, he designed the proposal of undergraduate degree in Primary Production of Milk. The same is born of a demand concrete of graduates of the career of medicine veterinary, requesting a proposal that train integrally to dairy. This educational offering, field staff and recalling that thinking in education is to be able to think in integral formative instances, is designed knowing the profile of the recipients. From virtuality it has given an offer training for people who for various situations could not reach such knowledge in a formal way. The importance of distance education as a resource for the inclusion of students in the educational system. Also the acquisition of knowledge of students and graduates who allow you up at their workplaces already available and\/or get jobs. Finally, the importance of UNL in giving answers to specific demands of the environment where it is inserted to support the growth of the region through the excellent training of human resources.Keywords:      Students, learning, teaching, tamberos, tecnicatura, university, virtuality?IntroducciónPensar en la educación es poder pensar en instancias formativas integrales que posibiliten una formación que supere lo netamente informativo para vislumbrarse como un espacio de crecimiento personal, constituyendo a la universidad en espacios de educación para la vida. La  educación, al decir de Linazas, no apunta a llenar cabezas sino a posibilitar una formación integral, que permita contemplar como variable transversal el análisis de los procesos que atraviesan los estudiantes, y el valor primigenio que contempla el desafío diario de forjar y prodigar una formación integral, que no sólo viabilice saberes sino también que permita asumir a la enseñanza como una reconstrucción por parte del sujeto de saberes y conocimientos que ha de inscribir en su proyecto y de los que ha de percibir en qué contribuyen a su desarrollo (Meirieu, 1998) para otorgar de sentido aquello que elige ser y hacer. Introducirnos en este campo nos permite forjar habilidades y competencias que se ajusten a las demandas del hoy, siendo estas habilidades o soft skills, denominadas como aquellos ?atributos, destrezas o características personales que nos permiten interactuar de manera efectiva con los demás, y son resultado de una combinación de habilidades sociales, de comunicación, de acercamiento a los demás y de otros factores que facilitan las relaciones y la comunicación efectiva con las personas?. Por su parte, las habilidades duras ('hard skills') tienen relación con los requerimientos formales y técnicos que nos permiten realizar una determinada actividad; por ejemplo el conjunto de conocimientos teóricos prácticos que un médico veterinario posee al realizar una cirugía. En los últimos años las 'soft skills' o competencias sociales han cobrado mayor importancia para los diversos ámbitos de trabajo, que la misma experiencia diaria ha puesto de manifiesto que en la labor y quehacer profesional no solo se necesita de la preparación técnica sino fundamentalmente capacidades vinculadas al trabajo en equipo, a la asunción del liderazgo, a la colaboración con los demás, a la capacidad de escucha, a la motivación, resultando habilidades centrales para que el desempeño actual (Apiquián 2014).  De este modo, pensar en la educación, es pensar en la interrelación existente entre teoría y práctica, poiesis y praxis, que permite fundar la formación de vínculos fluidos y entrelazados por su fundamental intervención, ya que una educación reducida a la poiesis implica la cosificación del sujeto que aprende, reduciéndolo a ciertos fragmentos desgajados de su integralidad, que sólo persigue una búsqueda, corroborar si ?este? se ajusta a lo proyectado, la praxis en cambio, propone obrar con actores, con sujetos singulares que se comprometen y se encuentran en base a su no-dominio del sentido y de la imprevisibilidad de lo que puede derivar su compromiso y encuentro. Si el formador asume esta convicción póstuma de que su lugar resulta ser de mediador, de guía en el encuentro con el otro, en el respeto por su ser, en la concepción de una formación integral, seguramente los recursos que instrumentaría en esta escenografía educativa serán la posibilidad y oportunidad de crear espacios donde todos y cada uno pueda ser desde lo que se desea y lo que se es, enriqueciendo intrínsecamente las convicciones que desde cada cual operan en sí, fruto de la historización personal. Es necesario analizar los componentes que involucra y tomar conciencia que el aprendizaje y la enseñanza son instancias sistemáticas, siendo ?la tarea más difícil? poner la cultura científica en estado de movilización permanente, reemplazar el saber cerrado y estático por un conocimiento abierto y dinámico, dialectizar todas las variables experimentales, dar finalmente a la razón motivos para evolucionar? (Bachelard 1948)En este marco referencial las Tecnologías de la Información y las Comunicaciones (TICS) permiten favorecer al acceso universal a la educación, en el ejercicio de la igualdad de oportunidades y el fomento de la inclusión educativa como principio rector del proceso educativo. El aprendizaje móvil, también llamado en inglés ?m-learning? ofrece métodos modernos de apoyo al proceso de aprendizaje mediante el uso de instrumentos móviles, tales como los ordenadores portátiles y las tabletas informáticas, los lectores MP3, los teléfonos inteligentes (smartphones) y los teléfonos móviles, al presentar características singulares y diferenciadoras del aprendizaje tradicional, permiten concretar alcances valorativos vinculantes a la cooperación, interacción y personalización del recorrido educativo. Los aspectos distintivos de este enfoque dejan acceder al conocimiento en todo momento y lugar, creando dispositivos de ayuda al aprendizaje formal e informal, poseyendo un enorme potencial para transformar las prestaciones educativas y la capacitación. En definitiva, a través de las TIC junto a otras herramientas adecuadas para la transmisión de los contenidos que se desean enseñar, podemos lograr la armonía entre la poiesis y la praxis mediatizada por la educación a distancia. Los estudiantes en un entorno virtual, adquieren competencias avanzadas relacionadas con la gestión de la información y los recursos, con la interacción y comunicación en entornos TIC, con la autorregulación y el control de su propia actividad (planificación del tiempo, cumplimiento de compromisos, etc.); además, cuando trabajan en situaciones de aprendizaje colaborativo, adquieren competencias avanzadas relacionadas con la colaboración y el trabajo en equipo (gestión de roles y tareas o capacidad de argumentación y negociación), participación en comunidades o generación de conocimiento.En el contexto actual, la Universidad Nacional del Litoral (UNL) y desde la Facultad de Ciencias Veterinarias en particular, teniendo presente sus funciones sustantivas (Enseñanza-Investigación-Extensión) y adecuándose a los permanentes cambios en el medio donde se inserta, participa desde hace ya 16 años, en el Programa de Educación a Distancia de UNLVIRTUAL. Dicho programa consta de una propuesta pedagógica adecuada a las nuevas Tecnologías de la Información y las Comunicaciones, enriquecidas con el desarrollo de material impresos, videos educativos y la utilización de la plataforma virtual generados desde el Centro Multimedial de Educación a Distancia (CEMED) de la UNL. Actualmente se ofrecen diferentes propuestas de pregrado, las mismas presentan título de validez nacional, las que pueden cursarse con una duración  de 2 y ½ años, brindando una formación técnica vinculada a la demanda concreta del mercado laboral. A partir de lo expuesto, se desarrollará en el presente trabajo, la experiencia que se originó en el diseño, ejecución y mantenimiento de una de estas propuestas educativas a distancia. La misma, es llevada a cabo por un equipo docente de dos unidades académicas, cuyos destinatarios son personas que se relacionan directa o indirectamente con la producción primaria de leche.Texto PrincipalLa complejidad de los sistemas productores de leche, ha obligado a trabajar de manera cada vez más eficiente en todos sus eslabones y adecuarse rápidamente a los nuevos tiempos. Aunque cada uno de las partes que forman el sistema productivo es importante, existen algunos que resultan esenciales. Entre éstos merecen citarse los Recursos Humanos que, dependiendo de la estructura organizativa de la empresa, requieren una formación más específica. De ahí que su formación y capacitación permanente sean imprescindibles para el buen funcionamiento de la empresa y para generar una toma de decisión más pertinente.Existe en el medio una creciente demanda de personal competente para llevar a cabo distintas tareas en las empresas tamberas, no sólo por parte de productores que solicitan personal, sino también por parte de jóvenes que desean iniciar un emprendimiento productivo o mejorar el desempeño de las empresas familiares. Resulta crucial el aporte que han vertido los egresados de la Facultad de Ciencias Veterinarias, por la pertinencia de sus contribuciones, ya sea vehiculizando demandas concretas del medio, las que han resultado ser el móvil inaugural del origen de la propuesta, como por el plus enriquecido en las tareas y funciones que desempeñan hacia el interior de la facultad, consistente en el ejercicio de roles de consejeros que permiten complementar una mirada total en consonancia con los requerimientos sociales y profesionales evidenciados. Estos recursos humanos han atravesado vivencias formativas que permiten fortalecer y constituir sólidas experiencias en especialidades asociadas a la producción primaria de leche y específicamente con el sector agropecuario.Fundada en esta razón la Facultad de Ciencias Veterinarias observa con interés acercar y conformar una instancia de creación de la ´Tecnicatura en Producción Primaria de Leche´ como carrera compartida con la Facultad de Ciencias Agrarias (UNL), cuyo perfil técnico contribuirá a formar egresados con competencias para satisfacer esas demandas del mercado laboral.Finalmente, el diseño de esta nueva propuesta académica contribuye al fortalecimiento y concreción de las políticas de integración académica que promueven el trabajo coordinado y cooperativo entre las distintas Facultades de la UNL. La flamante propuesta académica, tal como se mencionara denominada, nace en el 2012. Por tal motivo, es relativamente nueva como propuesta. La Tecnicatura en Producción Primaria de Leche presenta su sede en la Facultad de Ciencias Veterinarias de la Universidad Nacional del Litoral, ubicada en la ciudad de Esperanza en la provincia de Santa Fe (Argentina), esta carrera que busca capacitar a técnicos para aprender a gestionar adecuadamente una empresa tambera con el fomento de una sólida formación en aspectos vinculantes a la producción de leche desde una visión integral, para responder a los requerimientos de profesionales y empresarios. Además se busca detectar en forma preventiva y precoz aquellas debilidades y fortalezas en la producción lechera como así también aquellos factores que pudieran afectar el trabajo y-o éxito de la empresaEl Título de validez nacional que se le otorga, se denomina Técnico Universitario en Producción Primaria de Leche. En cuanto al Perfil del Egresado, se caracteriza en un técnico que recibirá una visión integradora de todos los componentes que conforman un sistema de producción leche, que le permitirá desempeñar tareas de apoyo a los profesionales del sector, en el control de procesos productivos y la aplicación de las normas de seguridad e higiene en el trabajo, en el relevamiento y registro de datos productivos y económicos, en la organización del trabajo y manejo del personal en un ambiente colaborativo. También, el graduado contará con los recursos necesarios para continuar su formación y para colaborar en la capacitación de las personas con las que desempeñe sus tareas.Por su parte los Alcances del Título, brindarán capacitación en el ordeño a fin de obtener un producto de calidad superior, pudiendo estar habilitado en la ejecución de las acciones vinculadas al manejo general y reproductivo del rodeo lechero, asegurando las condiciones de bienestar animal. Además podrá ejecutar prácticas del manejo nutricional  y sanitario del rodeo lechero. Podrá prever las dificultades y\/o problemas que emerjan en el desempeño de las actividades rutinarias, colaborando en la gestión de la empresa mediante la carga de datos en el registro correspondiente y la organización del trabajo, a los efectos de  mejorar su eficiencia, buscando en todo momento lograr un desarrollo integral y eficiente de la empresa agropecuaria.En lo que respecta a la Estructura Curricular, la misma al igual que todo el diseño de la propuesta académica en cuestión, fue pensada en base a las realidades de los posibles destinatarios de la misma. Entendiendo por destinatario toda persona que habiendo culminado sus estudios secundarios y se encuentre desarrollando o no actividades relacionadas con la producción lechera, quiera formarse en esta temática. En este sentido cabe aclarar lo complejo que representa la rutina de trabajo en un sistema de producción primaria de leche. La misma, comprende desde un principio que los animales se deben ordeñar dos veces al día todos los días del año, sumados a todas las tareas conexas al ordeñe, llámese alimentación, crianza artificial de terneros, detección de celos, cuidados sanitarios del rodeo, por solo enumerar algunas tareas diarias llevadas a cabo por el personal. Por tal motivo, la estructura curricular se diseñó en 15 módulos y un Trabajo Final. La Nómina de las asignaturas y su distribución por cuatrimestre se exponen a continuación:La Tecnicatura en Producción Primaria de Leche, con una duración de dos años y medio, presenta las asignaturas con una duración de 12 semanas cada una, aproximadamente. Durante ese lapso, los docentes responsables, van habilitando los contenidos académicos y trabajos prácticos, previamente diseñados para el cursado. Los trabajos prácticos requieren que el alumno se contacte y visite un establecimiento productor de leche de su zona para responder y enviar las consignas. Posteriormente el docente las corrige y le informa al alumno la nota respectiva. En este tipo de enseñanza a distancia los estudiantes y los docentes no están, necesariamente, en el mismo lugar físico y muchas veces tampoco coinciden en el tiempo en el que realizan las tareas mencionadas. Es por ello, que el docente en educación a distancia debe conocer y lograr una empatía con sus estudiantes. Tal docente debe identificar al alumno que desea pasar directamente a la acción o resolución de actividades, o el que quiere investigar un poco más antes de realizar alguna actividad, o aquel desea preguntar buscando ayuda o consejos antes de actuar. Todo a fin de orientar al alumnado en su forma de aprendizaje en la modalidad a distancia utilizando la amplia gama de herramientas disponibles en el aula. Tales herramientas como el Foro (asincrónico), Chat, Correos, Enlaces entre otras, que permiten diseñar el ámbito apropiado para una relación que desde la virtualidad se transforme en tangible. Algunas de las asignaturas del Primer año son por ejemplo: Introducción a los Sistemas de Producción Lechera, Anatomía y Fisiología del Aparato Digestivo del Bovino Lechero, Alimentación del Rodeo Lechero, Manejo Reproductivo; Mejoramiento Animal; Crianza Artificial de Terneros. Durante el segundo año, las asignaturas que deben cursar son: Anatomía y Fisiología de la Lactación, Rutina de Ordeño e Instalaciones, Profilaxis Sanitaria de Rodeos Lecheros, Bienestar Animal, Mecanización Agrícola, Los Recursos Humanos en la Empresa Tambera. Herramientas de Gestión Administrativa. Durante el quinto cuatrimestre, el deberá alumno integrar en una situación concreta de visitas a un establecimiento productor de leche, los conocimientos adquiridos durante el cursado de la Tecnicatura. Consistirá en establecer un diagnóstico de situación, detectando en base a lo aprendido, las fortalezas y debilidades del establecimiento, sugiriendo a su entender, las posibilidades de mejoras o alternativas a implementar para cambiar la situación. Para la realización de este Trabajo Final, se le asignará al alumno un Tutor proveniente del cuerpo docente de la Tecnicatura, relacionado al tema que desarrollará. Deberá cumplimentar un informe escrito, supervisado por el Tutor y posteriormente, defendido ante un tribunal conformado con profesores de la Tecnicatura en un turno de examen. Un recurso interesante y muy utilizado son los foros. Un estudio realizado por el CEMED (Centro Multimedial de Educación a Distancia) determinó que los resultados observados a partir del planteo de una actividad realizada en el foro (el cual supone la participación e interacción activa de los alumnos), puede devenir en un tipo de aprendizaje cooperativo. Esta actividad, herramienta tradicional en las aulas virtuales, es un claro ejemplo de construcción colectiva del conocimiento, ya que si no se trabaja en forma colaborativa, esta no podría llevarse a cabo.Esta es una herramienta asincrónica, muy usada para la comunicación y puede ser tomada como medio para desarrollar una actividad dinámica, participativa y enriquecedora que favorece y soporta a la enseñanza. La participación en los foros es una actividad que permite el intercambio de posiciones sobre un tema específico, habilitando a cada usuario para poder expresar sus ideas o comentarios, de manera pública, socializando así sus opiniones y escuchando las de sus compañeros. En estos espacios de comunicación se evidencian las opiniones compartidas por un grupo de personas cohesionadas por un interés común. Asimismo, es ?un espacio de interacción discursiva en el cual sujetos con diferentes niveles de experiencia cultural y lingüística se presentan a sí mismos, negocian su imagen y sus propósitos comunicativos?. Los docentes utilizan estos espacios para que los alumnos se presenten al inicio del cursado, realicen consultas o expresen inquietudes, como así también para realizar evaluaciones de un tema proponiendo una pregunta a la que los estudiantes deben responder.Las fortalezas de estudiar a distancia son amplias, desde el logro de una disciplina personal, reflejada en la constancia de ingresar semanalmente o diariamente a la plataforma para participar de las actividades previstas hasta el fortalecimiento de la capacidad de autogestión, de interpretación y relación, sumada a la mejora de la comunicación escrita y al desarrollo de competencias para trabajar colaborativamente y en equipo.Por otra parte, al trascender las barreras físicas, la modalidad virtual se constituye en una oportunidad para socializar con personas que viven en distintos lugares del país y del mundo, y participar incluso en distintas iniciativas que ellas impulsen.Una de las ventajas principales de la educación a distancia es su capacidad inclusiva y, por tanto, la mayor oportunidad de acceso que ofrece a segmentos sociales bien identificados, los estudios a distancia poseen una ventaja singular y ella refiere a la perspectiva social ya que colabora con el acceso, permanencia y oportunidad de obtención de los beneficios de la cultura y la inclusión social que ella propicia. Los estudiantes en un entorno virtual, adquieren competencias avanzadas vinculadas con la gestión de la información y los recursos, con la interacción y comunicación en entornos, con la autorregulación y el control de su propia actividad (planificación del tiempo, cumplimiento de compromisos, etc.); además, cuando se trabaja en situaciones de aprendizaje colaborativo, se adquieren competencias relacionadas con la cooperación y el trabajo en equipo (gestión de roles y tareas o capacidad de argumentación y negociación),Una debilidad que posee este sistema educativo es la necesidad de una intervención activa del tutor y\/o docente para evitar el potencial aislamiento y dispersión que puede tener el alumno que estudia en esta modalidad. En nuestra tecnicatura y debido a que muchos de los alumnos trabajan y no disponen del tiempo completo para el estudio, el docente debe hacer un seguimiento continuo del acceso de los estudiantes al aula.ConclusionesLa creación de la Tecnicatura en Producción Primaria de Leche por parte de la Facultad de Ciencias Veterinarias y Ciencias Agrarias, con sede en la primera Unidad Académica, ha sido una respuesta más de la Universidad Nacional del Litoral a las actuales demandas de formación. Asimismo permitió la creación de un equipo de trabajo interdisciplinario entre ambas Unidades Académicas e inter-cátedras lo que se expresó en mejores ofertas en las metodologías de enseñanza, nuevos proyectos entre otras acciones desde el equipo creado ad doc para la Tecnicatura. Se logró apreciar que el perfil de los destinatarios pensado en su momento se modificó en gran medida, ya que actualmente se encuentran imbuidos con la actividad tambera y modifican el sentido de apropiación, otros en cambio la vislumbran como una propuesta atractiva desde el punto de vista de salida laboral. Existe un nutrido grupo de alumnos que son a su vez estudiantes activos de Ciencias Veterinarias y Ciencias Agrarias,  otros alumnos son Licenciados en Administración Rural y desean tener una visión integral del sistema de producción lechera y por estas razones, realizan la Tecnicatura. Por su parte también existen alumnos que trabajan en industrias lácteas de la zona de la Facultad y elijen la propuesta como una póstuma forma para ascender laboralmenteAmén del amplio perfil que caracteriza a la propuesta académica, todos afirman que la modalidad a distancia le permite ?organizar su tiempo? para estudiar y rendir. Asimismo enfatizan que, por el momento, es la única forma que disponen para capacitarse y obtener un título de validez nacional y ser alumno de la Universidad Nacional del Litoral en esta propuesta relacionada a la producción primaria de leche desde un punto de vista integral.El promedio de Aspirantes aunque ha sido sustancialmente menor al esperado, ha sido de 30 alumnos cada cohorte, efectivizándose en 18 los alumnos activos por año. Ya son seis los egresados hasta el momento. Si bien los planes de estudios de las Tecnicaturas están organizados para una duración de 2 años y medio, en promedio los primeros egresados culminaron sus estudios a los 3 años de comenzada la propuesta educativa. Los mismos, a pesar que ya se encontraban trabajando a la hora de comenzar la Tecnicatura coincidieron que la misma le permitió a algunos ascender en sus puestos de trabajo y a otros implementar sus conocimientos adquiridos durante la carrera en los establecimientos donde se desarrollan laboralmente. Actualmente se sigue trabajando en la actualización de contenidos de las asignaturas, incorporar las sugerencias de alumnos y egresados; con el fin de mejorar la calidad educativa de la Tecnicatura en Producción Primaria de Leche y poder acrecentar la labor sustancial de Educación, Extensión e Investigación que ha caracterizado siempre a la Facultad de Ciencias Veterinarias de la Universidad Nacional del Litoral. Porque en el acto heroico de permitirse arriesgarse a una elección diferente, se asume la acción que despliega el ser en todo su esplendor, despojándose de las cadenas y cegueras vendidas, para transitar senderos que sean guiados por la luz propia emanada de las experiencias de la vida y de los aprendizajes conquistados sólo y gracias a permitirse y ofrecerse una oportunidad de hacerlo por sí mismo, ya que el sabor probado es un sabor disfrutado, más que el sabor contado por quien ha sido el gestor gastronómico de ese único menú ofrecido. Bajo este estandarte se resalta lo valeroso y altruista que transparenta la tarea de brindar oportunidades y espacios a quien aprende lo que aprende (Fascendini. 2016) ya que no se ha dado el caso de que un ser humano haya alcanzado el estatus de adulto sin que hayan intervenido en su vida, otros seres humanos, (Meirieu 1998),el hombre se caracteriza por su capacidad para aprender, y adaptarse a nuevos contextos, vivencias y circunstancias, apostando a sus potencialidades y fortaleciendo su ser, por ello resulta crucial sostener estos espacios constructivos del aprendizaje y ajustadas a las posibilidades contextuales, para no añorar ideales sino para hacerlos posibles.Referencias1.P. Meirieu, ?Frankestein educador? Ed. Laertes. Barcelona. Pag 31, 19982.A, Apiquián. ?8 competencias sociales que debes desarrollar? 2014 [online]. Disponible: http:\/\/www.altonivel.com.mx\/45135-8-competencias-sociales-que-debes-desarrollar-en-el-trabajo.html3.G. Bachelard, ?La formación del espíritu científico. Contribuciones a un psicoanálisis del conocimiento objetivo. Ed.  Argos Bs.As, 19484.P. Fascendini ?Estrategias metacognitivas: el ingreso a la universidad. ¿Cómo aprende el que aprende??. Editorial Académica Española. Alemania, 2016","palabras_clave":"ALUMNOS |APRENDIZAJE|ENSEÑANZA|TECNICATURA|UNIVERSIDAD|VIRTUALIDAD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14494,"idioma_id":4,"titulo":"Pushing precipitation to the extremes in distributed experiments: recommendations for simulating wet and dry years","resumen":"Intensification of the global hydrological cycle, ranging from larger individual precipitation events to more extreme multiyear droughts, has the potential to cause widespread alterations in ecosystem structure and function. With evidence that the incidence of extreme precipitation years (defined statistically from historical precipitation records) is increasing, there is a clear need to identify ecosystems that are most vulnerable to these changes and understand why some ecosystems are more sensitive to extremes than others. To date, opportunistic studies of naturally occurring extreme precipitation years, combined with results from a relatively small number of experiments, have provided limited mechanistic understanding of differences in ecosystem sensitivity, suggesting that new approaches are needed. Coordinated distributed experiments (CDEs) arrayed across multiple ecosystem types and focused on water can enhance our understanding of differential ecosystem sensitivity to precipitation extremes, but there are many design challenges to overcome (e.g., cost, comparability, standardization). Here, we evaluate contemporary experimental approaches for manipulating precipitation under field conditions to inform the design of ?Drought-Net?, a relatively low-cost CDE that simulates extreme precipitation years. A common method for imposing both dry and wet years is to alter each ambient precipitation event. We endorse this approach for imposing extreme precipitation years because it simultaneously alters other precipitation characteristics (i.e., event size) consistent with natural precipitation patterns. However, we do not advocate applying identical treatment levels at all sites ? a common approach to standardization in CDEs. This is because precipitation variability varies >fivefold globally resulting in a wide range of ecosystem-specific thresholds for defining extreme precipitation years. For CDEs focused on precipitation extremes, treatments should be based on each site´s past climatic characteristics. This approach, though not often used by ecologists, allows ecological responses to be directly compared across disparate ecosystems and climates, facilitating process-level understanding of ecosystem sensitivity to precipitation extremes.","palabras_clave":"climate extremes|drought, field experiments|precipitation regimes|wet years"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14495,"idioma_id":5,"titulo":"Revisión de Modelos de Madurez en la Medición del Desempeño","resumen":"En un contexto tan dinámico como el actual, las pymes necesitan sistemas de medición de desempeño (SMD) que generen información útil, relevante y confiable para poder gestionar. Medir la madurez de los SMD es un paso fundamental para lograr su evolución a un estado ideal que permita un mejor control de los resultados y actuar en consecuencia. Teniendo en cuenta que las pymes no disponen de mecanismos idóneos de información, se pretende realizar una revisión bibliográfica de los modelos de madurez de SMD existentes para identificar los más factibles de aplicar en tales empresas. De tal revisión surgen como modelos más adecuados los propuestos por Wettstein y Kueng (2002) y Aho (2012), debido a su fácil aplicación y el bajo requerimiento de uso de recursos. Sin embargo, tales modelos no cuentan con una herramienta de evaluación, quedando su definición a cargo de la empresa.","palabras_clave":"Gestión del Desempeño|Modelo de Madurez|Medición del Desempeño|pymes"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14548,"idioma_id":4,"titulo":"Starting points in plant-bacteria nitrogen-fixing symbioses: intercellular invasion of the roots","resumen":"Agricultural practices contribute to climate change by releasing greenhouse gases such as nitrous oxide that are mainly derived from nitrogen fertilizers. Therefore, understanding biological nitrogen fxation in farming systems is benefcial to agriculture and environmental preservation. In this context, a better grasp of nitrogen-fxing systems and nitrogen-fxing bacteria-plant associations will contribute to the optimization of these biological processes. Legumes and actinorhizal plants can engage in a symbiotic interaction with nitrogen-fxing rhizobia or actinomycetes, resulting in the formation of specialized root nodules. The legume-rhizobia interaction is mediated by a complex molecular signal exchange, where recognition of different bacterial determinants activates the nodulation program in the plant. To invade plants roots, bacteria follow different routes, which are determined by the host plant. Entrance via root hairs is probably the best understood. Alternatively, entry via intercellular invasion has been observed in many legumes. Although there are common features shared by intercellular infection mechanisms, differences are observed in the site of root invasion and bacterial spread on the cortex reaching and infecting a susceptible cell to form a nodule. This review focuses on intercellular bacterial invasion of roots observed in the Fabaceae and considers, within an evolutionary context, the different variants, distribution and molecular determinants involved. Intercellular invasion of actinorhizal plants and Parasponia is also discussed.","palabras_clave":"ACTINORHIZAL PLANTS|INTERCELLULAR INVASION|LEGUMES|MOLECULAR SIGNALING|RHIZOBIA|SYMBIOSES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14583,"idioma_id":5,"titulo":"Estrategias de interacción universidad-sectores productivos: Antecedentes y situación actual en las universidades de gestión estatal argentinas (1990-2015)","resumen":"En el presente estudio se describen las estrategias de vinculación que llevan adelante las universidades de gestión estatal en Argentina y las tendencias recientes para abordar las relaciones entre los sectores productivos y la universidad. Para el análisis, en primer lugar, se utilizó una tipología específica distinguiendo tres grandes campos de actuación: las estrategias de promoción y difusión, las estrategias de servicios y las estrategias de cooperación. En el primer tipo de estrategia se agruparon los vínculos que tienen como objetivo difundir las capacidades de investigación científica de la universidad. En el segundo campo, se agruparon las actividades que tienen como finalidad la promoción y venta de la oferta tecnológica de la universidad a través de la realización de servicios de consultoría, formación e investigación. El último campo, se refiere a las actividades de cooperación con actores públicos y privados que incluye compromisos institucionales más amplios. En este marco, el artículo busca contribuir en un doble sentido, por un lado, generar conocimiento empírico sobre las universidades de gestión estatal argentinas y por otro, enriquecer los estudios que abordan las relaciones entre la universidad y los sectores productivos.","palabras_clave":"VINCULACION |ESTRATEGIAS|UNIVERSIDAD|PRODUCCION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14589,"idioma_id":4,"titulo":"Rethinking specificity in defeasible reasoning and its role in argument reinstatement","resumen":"An argument is reinstated when all its defeaters are in turn ultimatelydefeated. This is a kind of principle governing most argument systems in AI.Nevertheless, some criticisms to this principle have been offered in the literature.Assuming that reinstatement is prima facie acceptable, we analyze some coun-terexamples in order to identify common causes. As a result, we found that theproblem arises when arguments in a chain of attacks are related by speci&#64257;city:when non-maximally speci&#64257;c arguments are reinstated, fallacious justi&#64257;cationsare originated. Particularly, we show how the problem affects DeLP, a systemthat combines a speci&#64257;city-based defeat criterion with a warrant process satisfy-ing reinstatement. Following old intuitions by Carl Hempel about the speci&#64257;cityof inductive explanations, we propose to rethink the concept of speci&#64257;city in de-feasible argumentation. Our analysis leads us to propose a general requirement ofmaximal speci&#64257;city for defeasible reasoning. We identify two kinds of speci&#64257;citydefeaters that make an argument non-maximally speci&#64257;c: proper defeaters andcautious defeaters. While proper defeaters are well-known, cautious defeaters areformally introduced here. A system combining cautious and proper defeaters isde&#64257;ned as an extension of DeLP, and dialectic warrant games are proposed for&#64257;ltering out non-maximally speci&#64257;c arguments.","palabras_clave":"ARGUMENT SYSTEMS|SPECIFICITY|REINSTATEMENT|DEFEAT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14597,"idioma_id":5,"titulo":"Be Civic: An Immersive Serious Game","resumen":"Nowadays, serious games is one of the biggest existing industries and it is still growing steadily in many sectors. Particularly, the use ofvirtual worlds and serious games in education is growing. This paper introduces the development of a serious game in an immersive learning environment for teaching Civics. The work´s idea is to develop a game to motivate, educate and train learnerson civic rules by placing users in differentcivic roles and giving them agency to address real-world problems andissues.In order to improve the user´s experience, the gamewas developed to work in a cave-like immersive environment by using aconversational character for a new kind of Human-ComputerInterface. The game includes static and dynamic 3D environments, allowing playersto share the experience of navigation in the scene among users, evengeographically distributed. In order to evaluate the game´s performance, a thirty participants experiment group was set up.","palabras_clave":"Virtual Character|Virtual Reality|Serious Games|CAVE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14599,"idioma_id":5,"titulo":"Análisis de imágenes relacionadas con día\/noche, estaciones y fases lunares en textos de enseñanza primaria","resumen":"Las investigaciones relacionadas con la enseñanza y el aprendizaje acerca de los fenómenos astronómicos cotidianos ponen en evidencia que una gran proporción de estudiantes de los distintos niveles educativos, e incluso de docentes, poseen dificultades para la comprensión adecuada de los mismos. Aquí se presenta un análisis centrado en la hipótesis de que algunas de dichas dificultades pueden ser causadas por el modo en que se desarrolla el tema en los libros escolares.Particularmente, se centra la atención en las imágenes presentes en textos de educación primaria en los que se pretende explicar el ciclo día\/noche, las estaciones del año y las fases lunares. Se detectaron gran cantidad de errores conceptuales y didácticos, lo que refuerza la hipótesis planteada y sugiere la necesidad de revisión del modo en que son producidos este tipo de materiales educativos.","palabras_clave":"Imagenes|Libros|Astronomia|Errores"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14600,"idioma_id":4,"titulo":"Effect of 'Whitemouth Croaker^ (Micropogonias furnieri, Pisces) on the Stability of the Sediment of Salt Marshes?an Issue To Be Resolved","resumen":"Among the predators, fish are prevalent in intertidalsoft-bottom zones, and many create substantial interruptionsin the sediment surface through their feeding, thus affectingthe movement of fluids in the sediment-water interface andtherefore the rates of deposition and local erosion. This studywas designed to determine whether or not Micropogoniasfurnieri?an ecologically significant benthophagic southwesternAtlantic Ocean predator?modified erosion and\/or sedimentationprocesses in salt marshes. The results indicated thatthis species exhibited a preference for areas without vegetationcover at the time of feeding since a greater abundance of pitswas found in those environments. Moreover, the volume analysisof the pits in the two areas indicated that the size of thefish that had foraged in the sediment was significantly larger in the nonvegetated areas. The results of the M. furnieri-exclusionexperiment indicated that the presence of this sciaenidneither resulted in a decrease in benthic organisms in thenonvegetated areas nor affected the vertical distribution ofthe infauna. When M. furnieri was excluded, the sedimentexhibited higher critical-shearing and frictional-velocityvalues than in areas where M. furnieri had access and thereforewas less likely to be eroded. The data from these experimentsenabled us to conclude that the foraging action ofM. furnieri modified the stability of the sediment as a resultof the predatory pressure that the fish exerted on the organismsinhabiting the salt marshes, thus resulting in the generation ofelliptical depressions. That modification of the sediment stabilitywas evidenced in two principal ways: (i) a negativeeffect on the microphytobenthic organisms that decreasedthe concentration of extracellular polymeric substances inthe sediment and (ii) an increased roughness of the bottomand increased percentage of sand in the particle compositionof the sediment, where the fish had foraged.","palabras_clave":"Saltmarshes|Spartina alterniflora|Bahía Blanca estuary|bioturbation|nekton|polychaete|fish predation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14612,"idioma_id":5,"titulo":"VIGILANCIA DE LA SENSIBILIDAD A PENICILINA EN STREPTOCOCCUS AGALACTIAE RECUPERADOS DE EMBARAZADAS ENTRE LAS 35-37 SEMANAS DE GESTACIÓN","resumen":"Streptococcus agalactiae (SGB) es causa de infecciones severas en menores de tres meses. Meningitis, neumonía y sepsis son los principales cuadros en estos niños. Estas infecciones se encuentran entre las más graves que puede sufrir un individuo en sus primeras doce horas de vida. El niño adquiere la infección por transmisión vertical de la madre colonizada. Para prevenir la enfermedad neonatal se recomienda penicilina como droga de elección en la profilaxis intraparto (PIP) en embarazadas colonizadas. Sin embargo, actualmente se han detectado cepas con sensibilidad disminuida a penicilina por lo que resulta importante realizar la vigilancia de la sensibilidad al mismo para asegurar su utilidad durante la profilaxis. El objetivo de este trabajo fue determinar la sensibilidad a penicilina en cepas de SGB recuperados de mujeres embarazadas de 35-37 semanas de gestación. Se estudiaron 96 aislamientos y se determinó la sensibilidad por método epsilométrico Etest® (LIOFILCHEM, Italia), siguiendo las recomendaciones del Clinical Laboratory Standards Institute (CLSI). Se obtuvo la Concentración Inhibitoria Mínima (CIM) para cada aislamiento bacteriano. El 100% (96) de las cepas estudiadas fue sensible a penicilina con valores de CIM comprendidos entre 0,012 y 0,094 µg mL-1. Estos resultados indican que penicilina sigue siendo el antimicrobiano de elección durante la profilaxis intraparto, para la prevención de la enfermedad neonatal causada por SGB en nuestra región. Se destaca la importancia de la vigilancia epidemiológica de la sensibilidad a penicilina y a otros antimicrobianos para alertar sobre nuevos mecanismos de resistencia y adecuar estrategias de tratamiento.","palabras_clave":"STREPTOCOCCUS AGALACTIAE|ANTIMICROBIANO|PENICILINA|PROFILAXIS INTRAPARTO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14650,"idioma_id":4,"titulo":"Against cognitive artifacts: Extended cognition theory and the problem of defining ?artifact?","resumen":"In this paper I examine the notion of ´artifact´ and related notions (namely, ´cognitive artifact´) in the dominant version of extended cognition theory (ECT) grounded on extended functionalism. Although the term is ubiquitous in the literature, it is far from clear what ECT means by it. How are artifacts conceptualized in ECT? Is ´artifact´ a meaningful and useful category for ECT? If the answer to the previous question is negative, should we worry? Is it important for ECT to have a coherent theory of artifacts? And what are the demands and constraints that ECT imposes on this theory? I distinguish between two aspects of ECT, one narrow, aligned with extended functionalism (EF); and one broad or pluralistic, in which EF is combined with other theoretical resources in the context of diverse research programs. I begin by determining the problems in conceptualizing artifacts from EF. Then I address the question of why a concept of artifact may be relevant to ECT. Next, I examine the efforts of Richard Heersmink to combine ECT with dominant theories of artifacts in the philosophy of technology (ECT in its broad aspect). I argue that both approaches fail to yield a meaningful notion of artifact, let alone one of ´cognitive´ artifact. Finally, I argue that narrow ECT places rather strong constraints on a theory of artifacts, since it locates the specificity of ´artifact´ in material aspects of realization that are, by definition, outside its theoretical purview. I examine, then discard, the possibility that a materialist and objectivist theory of artifacts may be of help. And finally I briefly explore some ways in which a broad, pluralistic ECT may address some of these shortcomings.","palabras_clave":"Cognicion extendida|Filosofia de la tecnologia|Filosofia de la mente"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14717,"idioma_id":4,"titulo":"A calcium lactate treatment at harvest, growing system and refrigerated modified atmosphere can affect strawberry?s ´Camarosa´ postharvest quality?","resumen":"The aim of this work was to evaluate the effect of a calcium lactate treatment on postharvest behaviour, organoleptic and nutritional quality of strawberries (Fragaria x ananassa Duch., cv. Camarosa) grown in different growing systems and stored in refrigerated modified atmosphere. Strawberry grown in perlite and soil in greenhouse and soil in open field was harvested and dipped in a calcium lactate 1% solution. Fruits were packed in modified atmosphere at 1°C and 8°C. At 1, 3 and 7 days of storage postharvest behaviour, organoleptic and nutritional quality was evaluated. Calcium had a positive effect on fruit firmness and no differences were observed between storage temperatures in calcium treated fruits. Organoleptic quality (except visual quality) was better in fruits grown in open field soil, regardless calcium treatment and storage temperature. Nutritional quality was better in untreated fruits and stored at 1°C.","palabras_clave":": postharvest behaviour; |organoleptic quality;| nutritional quality; |storage temperature"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14778,"idioma_id":5,"titulo":"Concentración Económica y Comercio Internacional. La Condición Marshall-Lerner en la Argentina (1993-2013)","resumen":"El presente artículo estudia los efectos de la concentración económica en la pérdida de sensibilidad de la Balanza Comercial a las variaciones del Tipo de Cambio Real (TCR). Para esto analizan los flujos comerciales de la Argentina (1993-2013), con el doble objetivo de, por un lado, identificar el cumplimiento de la Condición Marshall-Lerner (CML) y, por otro, determinar la influencia de la concentración económica sobre la misma. Los resultados alcanzados muestran que los movimientos del TCR no generan cambios significativos en la balanza comercial. Sin embargo, cuando se aíslan los efectos directos e indirectos de la concentración económica, esta aumenta su sensibilidad al TCR y se cumple la CML.","palabras_clave":"CONCENTRACIÓN|COMERCIO |INTERNACIONAL|ARGENTINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14779,"idioma_id":4,"titulo":"Metalloproteinase 2 and 9 Activity Increase in Epicardial Adipose Tissue of Patients with Coronary Artery Disease","resumen":"AbstractBACKGROUND:Epicardial adipose tissue (EAT) is a visceral adipose tissue (AT) surrounding and infiltrating myocardium and coronary arteries. Increased EAT may represent a chronic inflammatory injury and represent a link with coronary artery disease (CAD). Metalloproteinases (MMPs) are involved in expansion of AT.OBJECTIVE:to evaluate MMP-2 and -9 behavior in EAT from coronary artery disease patients.METHODS:In EAT and subcutaneous AT (SAT) from patients undergoing coronary artery bypass graft (CABG, n=30) or valve replacement (No CABG, n=18), MMP-2 and -9 activity and localization, inflammatory cells and vascular endothelial growth factor (VEGF) levels were determined.RESULTS:In EAT from CABG, MMP-2 and -9 activity was increased compared with No CABG (p=0.041 and p=0.027 respectively) and compared to SAT (p=0.005 and p=0.048 respectively). Vascular density was higher in EAT from CABG than No CABG (p=0.015) and it was directly correlated with MMP-2 (p=0.006) and MMP-9 (p=0.02). VEGF levels in EAT were directly associated with MMP-2 (p=0.016).CONCLUSION:EAT from CABG presents higher gelatinases activity than No CABG. This finding reveals a potential role of MMPs in EAT expansion making their activity a potential treatment goal.","palabras_clave":"TEJIDO ADIPOSO EPICARDICO|METALOPROTEINASAS|ATEROSCLEROSIS|ENFERMEDAD CORONARIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14801,"idioma_id":4,"titulo":"Multivariate statistical analysis for estimating surface water quality in reservoirs","resumen":"Abstract: Regular water quality monitoring programs are an important aspect of water management. Different multivariate statistical techniques were applied for interpretation and evaluation of the data matrix obtained during a six years monitoring program (2006 to 2011) in the principal reservoirs of the central region of Argentina. Eleven sampling sites located in two reservoirs were surveyed each climatic season for 18 parameters. Cluster analysis grouped the sampling sites into three clusters and classified the different climatic seasons into two clusters based on their similarities. Principal component analysis\/factor analysis showed the existence of five significant varifactors (VF) which account for 79.3 % of the variance, related to soluble salts, nutrients, physico-chemical parameters, and non-common source. Source contribution was calculated using multiple regression of sample mass concentration on the absolute VF scores. This study demonstrates the usefulness of multivariate statistical techniques helping managers to get better information about surface water systems.","palabras_clave":"MONITORING PROGRAM| MULTIVARIATE STATISTICAL TECHNIQUES|RESERVOIRS|WATER QUALITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14838,"idioma_id":4,"titulo":"Differential expression of Low density lipoprotein Receptor?related Protein 1 (LRP-1) and Matrix Metalloproteinase-9 (MMP-9) in prostate gland: from normal to malignant lesions","resumen":"BackgroundMetalloproteinases (MMPs) are relevant modulators of inflammation, tumor microenvironment, cancer invasion and metastasis. They can be regulated by the Low density lipoprotein Receptor?related Protein 1 (LRP-1), a receptor reported to mediate the clearance of lipoproteins, extracellular matrix (ECM) macromolecules and proteinases. The aim of this study was to evaluate the expression of LRP-1, MMP-2 and MMP-9 across various grades of prostatic diseases as benign prostatic hyperplasia (BPH), BPH plus prostatitis (BPH + P), high grade prostatic intraepithelial neoplasia (HGPIN) and prostate cancer (PCa).MethodsLRP-1 was analyzed using immunohistochemistry and MMPs proteolytic activity by zymography in prostate tissues with different prostatic diseases.ResultsLRP-1 was detected in epithelial cells in BPH (16\/18), BPH + P (21\/21) and HGPIN (6\/6), with a staining intensity of 1+, 1+\/2+ and 3+, respectively. In PCa, LRP-1 was absent in 19\/27 samples while a low expression was observed in 8\/27 biopsies. MMP-9 activity was higher and statistically significant in PCa than in BPH (p &#8804; 0.01).ConclusionConsidering that LRP-1, by mediating the clearance of MMPs, is involved in the regulation of ECM remodeling and cell migration, we conclude that a decreased expression of LRP-1 could be involved with the increasing activity of MMPs shown in cancers.","palabras_clave":"Prostate |Cancer|LRP-1|MMP-9|Immunohistochemistry|Zymography"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14840,"idioma_id":4,"titulo":"Epigenetics regulates transcription and pathogenesis in the parasite Trichomonas vaginalis","resumen":"Trichomonas vaginalis is a common sexually transmitted parasite that colonizes the human urogenital tract. Infections range from asymptomatic to highly inflammatory, depending on the host and the parasite strain. Different T. vaginalis strains vary greatly in their adherence and cytolytic capacities. These phenotypic differences might be attributed to differentially expressed genes as a consequence of extra-genetic variation, such as epigenetic modifications. In this study, we explored the role of histone acetylation in regulating gene transcription and pathogenesis in T. vaginalis. Here, we show that histone 3 lysine acetylation (H3KAc) is enriched in nucleosomes positioned around the transcription start site of active genes (BAP1 and BAP2) in a highly adherent parasite strain; compared with the low acetylation abundance in contrast to that observed in a less-adherent strain that expresses these genes at low levels. Additionally, exposition of less-adherent strain with a specific histone deacetylases inhibitor, trichostatin A, upregulated the transcription of BAP1 and BAP2 genes in concomitance with an increase in H3KAc abundance and chromatin accessibility around their transcription start sites. Moreover, we demonstrated that the binding of initiator binding protein, the transcription factor responsible for the initiation of transcription of ~75% of known T. vaginalis genes, depends on the histone acetylation state around the metazoan-like initiator to which initiator binding protein binds. Finally, we found that trichostatin A treatment increased parasite aggregation and adherence to host cells. Our data demonstrated for the first time that H3KAc is a permissive histone modification that functions to mediate both transcription and pathogenesis of the parasite T. vaginalis.","palabras_clave":"EPIGENETIC|GENE TRANSCRIPTION|HISTONE ACETYLATION|PARASITE|PATHOGENESIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14867,"idioma_id":5,"titulo":"NANOTECHNOLOGY, A NEW PARADIGM IN THE ATHEROSCLEROSIS TREATMENT","resumen":"Atherosclerosis, a known and prevalent disease, causes progressive deterioration of affected vessels inducing a blood flow reduction with different complications and its symptoms usually manifest in advanced stages of the disease. Therefore, the classic therapeutic alternatives are insufficient because the damages are many times irreversible. For this reason, arises the need for implement intelligent forms of drug administration and develop new therapeutic targets than reduce the progression of atherosclerotic lesion. It?s of special interest the implementation of new tools for prevention, diagnosis and treatment of this and other cardiovascular pathologies, focusing our attention in achieving a more effective control on immune system. Finally, this review highlights the latest knowledge about nanotechnology as a powerful, modern and promisingtherapeutic alternative applied to atherosclerotic disease, however, we also warns of potential complications with their use.","palabras_clave":"ATHEROSCLEROSIS|NANOTECHNOLOGY|TREATMENT|DIAGNOSIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14910,"idioma_id":4,"titulo":"Structural and functional characterization of a cold adapted TPM-domain with ATPase\/ADPase activity","resumen":"The Pfam PF04536 TPM_phosphatase family is a broadly conserved family of domains found across prokaryotes, plants and invertebrates. Despite having a similar protein fold, members of this family have been implicated in diverse cellular processes and found in varied subcellular localizations. Very recently, the biochemical characterization of two evolutionary divergent TPM domains has shown that they are able to hydrolyze phosphate groups from different substrates. However, there are still incorrect functional annotations and uncertain relationships between the structure and function of this family of domains. BA41 is an uncharacterized single-pass transmembrane protein from the Antarctic psychrotolerant bacterium Bizionia argentinensis with a predicted compact extracytoplasmic TPM domain and a C-terminal cytoplasmic low complexity region. To shed light on the structural properties that enable TPM domains to adopt divergent roles, we here accomplish a comprehensive structural and functional characterization of the central TPM domain of BA41 (BA41-TPM). Contrary to its predicted function as a beta-propeller methanol dehydrogenase, light scattering and crystallographic studies showed that BA41-TPM behaves as a globular monomeric protein and adopts a conserved Rossmann fold, typically observed in other TPM domain structures. Although the crystal structure reveals the conservation of residues involved in substrate binding, no putative catalytic or intramolecular metal ions were detected. Most important, however, extensive biochemical studies demonstrated that BA41-TPM has hydrolase activity against ADP, ATP, and other di- and triphosphate nucleotides and shares properties of cold-adapted enzymes. The role of BA41 in extracellular ATP-mediated signaling pathways and its occurrence in environmental and pathogenic microorganisms is discussed.","palabras_clave":"TPM domain|X-ray crystallography|ATPase|NTPDases|psychrophiles|cold-adaptation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14914,"idioma_id":5,"titulo":"TRAYECTO UNIVERSITARIO, ESPACIO DE FORMACIÓN DEL ESTUDIANTE","resumen":"El propósito del trabajo es describir una experiencia con alcances de investigación de naturaleza institucional, desarrollada en la Universidad Nacional de Lomas de Zamora (Argentina), específicamente en la Facultad de Ciencias Económicas. La misma se originó a partir de la detección de un importante nivel de abandono estudiantil en las carreras de grado, el cual se registraba como sostenido y permanente desde hacía varios años. Se diseñaron y plantearon distintos ejes estratégicos y un conjunto importante de acciones basadas en criterios de calidad formativa: tanto al inicio como durante el desarrollo de los primeros años de las carreras, implementándose el ?Programa de Articulación con el Nivel Medio? con el fin de integrar las culturas de la educación secundaria y universitaria y el ?Programa de Retención de Alumnos? que se encargó de la promoción inmediata de acciones de efectiva implementación en la problemática del abandono durante los primeros años universitarios. Ambos programas conformaron el antes y el después del Curso de Nivelación o introductorio para ingresar a las carreras, este se proponía brindar información sobre el sistema universitario y a la vez reforzar conocimientos previos indispensables para iniciar los estudios de grado. El diseño de un trayecto a través de programas institucionales, permitieron trabajar el desarrollo integral del alumno como un espacio más de aprendizaje, y ocuparse de la problemática con acciones concretas que incorporaron verdaderos procesos de orientación e información efectiva desde antes de su ingreso a la vida universitaria y durante sus primeros años en ella.","palabras_clave":"ARTICULAR|NIVELAR|RETENER|TRAYECTO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":14984,"idioma_id":5,"titulo":"Análisis sobre la percepción frente al riesgo por inundación en dos barrios de Concepción del Uruguay, Entre Ríos, Argentina","resumen":"En  los  últimos  35  años,  en  la  región  del  Litoral  argentino,  casi  un  millón  de  personas han sido evacuadas en inundaciones; estadísticamente uno de cada 13 habitantes  ha  sido  afectado.  Muchos  actores  sociales,  a  pesar  de  haber  vivido  situaciones  de  inundación,  tienden  a  negar  las  consecuencias  o  a  menospre-ciar la ocurrencia del fenómeno. Este trabajo buscó identificar y caracterizar la amenaza  por  inundación,  conocer  la  población  en  riesgo  y  la  percepción  y  el  comportamiento  o  conducta  que  poseen  los  habitantes  de  los  barrios  Cantera  25 y San José y los funcionarios locales de la ciudad de Concepción del Uruguay frente  al  riesgo  por  inundación.  Se  emplearon  técnicas  cuantitativas  y  cualita-tivas  y  los  análisis  espaciales  se  realizaron  mediante  un  SIG.  Se  realizaron  150  encuestas en marzo y abril de 2013 y entrevistas semiestructuradas a funciona-rios,  concejales  de  la  Municipalidad;  representantes  de  Defensa  Civil  y  de  la  Cruz Roja.","palabras_clave":"PERCEPCIÓN DEL RIESGO|INUNDACIÓN|VULNERABILIDAD|DESASTRES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15034,"idioma_id":4,"titulo":"Selected lactobacilli and bifidobacteria development in solid state fermentation using soybean paste","resumen":"At present, consumers are looking for more natural foods and improve health through their active compounds. In this context, soybean is an excellent substrate due to its beneficial effects on consumer health. Moreover, lactic cultures are widely used in the food industry improving the technological, nutritional and functional characteristics of fermented foods. It is interesting to find new matrices in which to transport these starter cultures (potentially probiotic microorganisms). The aim of this research was to obtain a semisolid state fermentation system from soybean to analyze the behavior of selected lactobacilli and bifidobacteria, with the potential to develop a functional vegetarian food to serve as carrier for the microorganisms. A soybean solid substrate system was optimized by selecting the main processing parameters relationship. Soybean homogeneous paste with different moisture was obtained and used as substrate and support for solid substrate fermentation. Moisture, inoculum size, temperature were optimized: 80%, 4%, 37ºC, respectively. L. rhamnosus CRL 981 was chosen as the best starter to use in this kind of fermentation, showing high acidification and cell counts at 24h of fermentation and increased specific growth rate in tested soybean pastes. It was demonstrated that the selected soybean paste could be used as a carrier of these microorganisms with probiotic potential for the production of vegetarian foods. Besides, these microorganisms are able to modify the substrate to enhance their nutritional and functional characteristics changing the soybean in a more attractive product for consumers.","palabras_clave":"SOLID STATE FERMENTATION|SOYBEANS|LACTOBACILLI|BIFIDOBACTERIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15067,"idioma_id":4,"titulo":"Affinity chromatography matrices for depletion and purification of casein glycomacropeptide from bovine whey","resumen":"Casein glycomacropeptide (CMP) is a 64- amino acid peptide found in cheese whey, which is released after &#954;-casein specific cleavage by chymosin. CMP lacks aromatic amino acids, a characteristic that makes it usable as a nutritional supplement for people with phenylketonuria. CMP consists of two nonglycosylated isoforms (aCMP A and aCMP B) and its different glycosylated forms (gCMP A and gCMP B). The most predominant carbohydrate of gCMP is N-acetylneuraminic acid (sialic acid). Here, we developed a CMP purification process based on the affinity of sialic acid for wheat germ agglutinin (WGA). After formation of chitosan beads and adsorption of WGA, the agglutinin was covalently attached with glutaraldehyde. Two matrices with different WGA density were assayed for CMP adsorption. Maximum adsorption capacities were calculated according to the Langmuir model from adsorption isotherms developed at pH 7.0, being 137.0 mg\/g for the matrix with the best performance. In CMP reduction from whey, maximum removal percentage was 79% (specifically 33.7% of gCMP A and B, 75.8% of aCMP A, and 93.9% of aCMP B). The CMP was recovered as an aggregate with an overall yield of 64%. Therefore, the matrices developed are promising for CMP purification from cheese whey. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 33:171?180, 2017.","palabras_clave":"BOVINE WHEY|GLYCOMACROPEPTIDE|DEPLETION|PURIFICATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15068,"idioma_id":5,"titulo":"Adaptación de la escala de probabilidad de perdón a población adolescente argentina","resumen":"El objetivo de la investigación que se informa fue adaptar la Escala de Probabilidad de Perdón de Rye y colaboradores (2001) a una poblaciónadolescente argentina. A tal fin se realizaron dos estudios con residentes de la ciudad de Paraná (Argentina). El Estudio 1 tuvo como objetivo evaluarla validez factorial de la escala y con el Estudio 2 se puso a prueba el modelo de la escala surgido en el Estudio 1 a través de un análisis factorial confirmatorio. La muestra del Estudio 1 estuvo compuesta por 170 adolescentes (85 varonesy 85 mujeres), con una media de edad igual a 15.60 (DE = 1.30) y la muestra del Estudio 2 estuvo compuesta por 294 adolescentes (131 varones y 163 mujeres), con una media de edad igual a 15.60 (DE = 1.35). Para el Estudio 1 se realizóun análisis factorial ex ploratorio. Previamente se evaluó el índice de adecuación muestral de Kaiser-Meyer-Olkin (KMO = .78) y la prueba de esfericidadde Bartlett (&#967;2 = 317; p = .000), los cuales indicaron la pertinencia para realizar el análisis factorial exploratorio. Finalmente resultó un únicofactor que explicaba el 32.79% de la variancia. En cuanto a la consistencia interna de la escala se obtuvo un índice Alpha de Cronbach igual a .76para los diez ítems en la muestra de 170 adolescentes.Teniendo en cuenta el Estudio 2, el análisis factorial confirmatorio mostró un buen ajuste del modelo propuesto, con los siguientes resultados: &#967;2(32) = 86.27; p =.000, &#967;2\/gl = 2.69, CFI = .93, GFI = .94, RMR = .059 y RMSEA = .076. Laadaptación del instrumento mostró buenas propiedades psicométricas de la escala para su uso en población argentina.Palabras clave: Perdón; Adolescentes; Propiedadespsicométricas; Escala; Agravio.","palabras_clave":"Perdón|Adolescencia|Propiedades Psicométricas|Escala"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15077,"idioma_id":5,"titulo":"El castigo como relación social cotidiana en la Argentina actual. El caso de la cárcel de mujeres de Batán","resumen":"El artículo indaga las relaciones sociales a que están sujetas las castigadas en la cárcel N° 50 del Complejo Penitenciario Batán a partir del análisis de los castigos cotidianos. La fuente documental la constituye una copia del Libro de faltas de la cárcel que detalla los castigos aplicados desde junio de 2010 hasta agosto de 2013. Los hallazgos indican que los castigos cotidianos se caracterizan por su cinismo y violencia. Son polivalentes en sus funciones en la medida en que son una forma de gobierno directo, pero también contribuyen al funcionamiento de la tercerización del control carcelario, al funcionamiento de un mercado informal y al ocultamiento de prácticas de tortura. Por otro lado, permiten observar prácticas de resistencia de las castigadas y corroborar entonces que las relaciones de poder para mantenerse necesitan de un ejercicio cotidiano que garantice su reproducción.","palabras_clave":"SANCIONES DISCIPLINARIAS|MÉTODO DE GOBIERNO|CÁRCEL|CASTIGADAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15084,"idioma_id":4,"titulo":"Holocene changes in the trophic  ecology of an apex marine predator in the South Atlantic Ocean","resumen":"ABSTRACTPredators may modify their diets as a result of both anthropogenic and natural environmental changes. Stable isotope ratios of nitrogen and carbon in bone collagen have been used to reconstruct the foraging ecology of South American fur seals (Arctocephalus australis) in the southwestern South Atlantic Ocean since the Middle Holocene, a region inhabited by hunter-gatherers by millennia and modified by two centuries of whaling, sealing and fishing. Results suggest that the isotopic niche of fur seals from Patagonia has not changed over the last two millennia (average for the period: d13C2200-0BP = -13.4 ± 0.5?, d15N2200-0BP = 20.6 ± 1.1?). Conversely, Middle Holocene fur seals fed more pelagically than their modern conspecifics in the Río de la Plata region (d13C7000BP = -15.9 ± 0.6? vs. d13CPRESENT = -13.5 ± 0.8?) and Tierra del Fuego (d13C6400-4300BP = -15.4 ± 0.5? vs. d13CPRESENT = -13.2 ± 0.7?). In the latter region, Middle Holocene fur seals also fed at a higher trophic level than their modern counterparts (d15N6400-4300BP = 20.5 ± 0.5? vs. d15NPRESENT = 19.0 ± 1.6?). Nevertheless, a major dietary shift was observed in fur seals from Tierra del Fuego during the nineteenth century (d13C100BP = -17.2 ± 0.3?, d15N100BP = 18.6 ± 0.7?), when marine primary productivity plummeted and the fur seal population was decimated by sealing. Disentangling the relative roles of natural and anthropogenic factors in explaining this dietary shift is difficult, but certainly the trophic position of fur seals has changed through the Holocene in some South Atlantic regions.RESUMENLos depredadores pueden modificar sus dietas como resultado de cambios ambientales tanto antropogénicos como naturales. Se utilizaron las proporciones de isótopos estables de nitrógeno y carbono en el colágeno de hueso para reconstruir la ecología trófica del lobo fino (Arctocephalus australis) en el Océano Atlántico Sur Sudoccidental desde el Holoceno Medio, región habitada por cazadores-recolectores durante milenios y modificada por dos siglos de caza de ballenas y lobos marinos, y pesquerías. Los resultados sugieren que el nicho isotópico de los lobos finos de la Patagonia no ha cambiado en los últimos dos milenios (promedio del período: d13C2200-0AP = -13,4 ± 0,5 ?, d15N2200-0AP = 20,6 ± 1,1 ?). Por el contrario, los lobos marinos del Holoceno Medio se alimentaron más pelágicamente que sus congéneres modernos en la región del Río de la Plata (d13C7000AP = -15,9 ± 0,6 ? vs. d13CPRESENTE = -13,5 ± 0,8 ?) y en Tierra del Fuego (d13C6400-4300AP = -15,4 ± 0,5 vs. d13CPRESENTE = -13.2 ± 0.7?). En esta última región, los lobos finos del Holoceno Medio también se alimentaron a mayor nivel trófico que sus homólogos modernos (d15N6400-4300AP = 20.5 ± 0.5 ? vs. d15NPRESENTE = 19.0 ± 1.6 ?). Sin embargo, se observó un importante cambio en la dieta de los lobos finos de Tierra del Fuego durante el siglo XIX (d13C100AP = -17,2 ± 0,3 ?, d15N100AP = 18,6 ± 0,7 ?), cuando la productividad primaria marina se desplomó y la población de lobos finos fue diezmada por la caza. Desenmarañar los papelel relativos de los factores naturales y antropogénicos para explicar este cambio en la dieta es difícil, pero ciertamente la posición trófica de los lobos finos ha cambiado a través del Holoceno en algunas regiones del Atlántico Sur.RESUMOPredadores podem modificar suas dietas como resultado de mudanças antropogênicas e\/ou naturais no ambiente. As proporções de isótopos estáveis de nitrogênio e carbono no colágeno ósseo foram usadas para reconstruir a ecologia trófica dos lobos-marinhos-sul-americanos (Arctocephalus australis) no Oceano Atlântico Sul Ocidental desde o Holoceno Médio, uma região habitada por caçadores-coletores por milênios e modificada por dois séculos de caça comercial à baleia e aos lobos-marinhos, além de intensa atividade de pesca. Os resultados sugerem que o nicho isotópico dos lobos-marinhos na Patagônia não mudou nos últimos dois milênios (média do período: d13C2200-0BP = -13,4 ± 0,5 ?, d15N2200-0BP = 20,6 ± 1,1 ?). Contudo, os lobos-marinhos do Holoceno Médio se alimentaram de forma mais pelágica que os espécimes modernos na região do Rio da Prata (d13C7000BP = -15,9 ± 0,6 ? vs. d13CPRESENT = -13,5 ± 0,8 ?) e na Terra do Fuego (d13C6400-4300BP = -15,4 ± 0,5 ? vs. d13CPRESENT = -13,2 ± 0,7 ?). Nessa última região, os lobos-marinhos do Holoceno Médio também se alimentaram em um nível trófico mais elevado do que os espécimes modernos (d15N6400-4300BP = 20.5 ± 0.5 ? vs. d15NPRESENT = 19.0 ± 1.6 ?). No entanto, observou-se uma grande mudança na dieta dos lobos-marinhos da Terra do Fogo durante o século XIX (d13C100BP = -17,2 ± 0,3 ?, d15N100BP = 18,6 ± 0,7 ?), período que coincide com uma grande queda na produtividade primária marinha e com o declínio quase que total da população de lobos-marinhos devido a caça comercial. O esclarecimento da influência relativa dos fatores naturais e antropogênicos na explicação desta mudança na dieta dos lobos-marinhos é difícil, mas certamente a posição trófica destes animais tem mudado ao longo do Holocene em algumas regiões do Atlântico sul.","palabras_clave":"FUR SEALS |ARCTOCEPHALUS AUSTRALIS |HISTORICAL ECOLOGY |HUNTER-GATHERERS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15089,"idioma_id":5,"titulo":"Aportes de la Economía Política Internacional a la comprensión teórica de la relación entre el FMI y los países en desarrollo","resumen":"Si bien existe consenso en que el FMI tuvo éxito en globalizar y extender la dominación de las finanzas hacia los países en desarrollo, la relación entre este organismo y los países en desarrollo no constituye un vínculo en el cual el primero impone y los segundos acatan; ni tampoco uno en el cual el organismo se muestra inevitablemente disconforme frente a los incumplimientos de los países. La comprensión del sentido histórico de la relación y del cambiante equilibrio de fuerzas entre actores requiere analizar las sucesivas negociaciones mediante las cuales emergen y se resuelven los conflictos entre ambos actores. El objetivo de este trabajo es plantear una contribución sobre el estatus teórico de la relación entre el FMI y los países en desarrollo, dado su rol de principales tomadores de crédito, que recupera los aportes de la Economía Política Internacional sobre la importancia de los intereses y la contribución de la Sociología respecto de la crítica a la acción racional. Se propone un marco de análisis que permite considerar la relación entre el FMI y los países en desarrollo como un vínculo complejo y dinámico cuyo resultado no está determinado de antemano.","palabras_clave":"FMI|Países en desarrollo|Negociaciones|Intereses|Acción racional"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15103,"idioma_id":5,"titulo":"La preposición de en el español de Buenos Aires. Un estudio desde la Lingüística cognitiva","resumen":"Desde el punto de vista morfológico, la preposición es invariable. En esto coincide la totalidad de las gramáticas hispánicas. En cuanto a la naturaleza sintáctica y semántica de esta clase de palabra, no se encuentra el mismo consenso. La preposición encierra en principio tres problemas fundamentales: su significado (semántico y pragmático), su función en la oración, y las relaciones sintácticas en las que entra (o que establece) con el elemento que la antecede y con el que la sigue (sea éste visto como término o como complemento).Partiendo de la problemática que suscita la falta de caracterización clara del estatuto gramatical de la preposición de, el presente trabajo propone el estudio pragmático, semántico y sintáctico de la preposición de en contexto nominal, en el español de Buenos Aires. La investigación se enmarca en el Enfoque Cognitivo Prototípico (ECP) (Lakoff, 1987; Langacker, 1987; 1991; Geeraerts y Cuyckens, 2007, entre otros). De este enfoque teórico, se retomarán fundamentalmente los postulados que plantean que no existen formas lingüísticas sin significado y que a cada forma le corresponde un valor semántico específico, que proviene de la regularidad de su empleo en el discurso. La preposición de, entonces, tiene significado. Ese significado presenta una estructura de categoría radial (Lakoff, 1987), cuyo significado central es el de posesión. Este significado básico se combina con el de los elementos que la rodean para establecer los significados restantes. En cuanto al estatuto sintáctico, la preposición de manifiesta dos grados de coherencia. Así, la relación que se establece entre los nombres en estructuras del tipo La casa de Juan corresponde o bien a la relación sintáctica de centro-periferia (Matthiessen y Thompson, 1988) o bien a la relación de coordinación, según el contexto discursivo. Pragmáticamente, la preposición de tiende a introducir el elemento periférico de la construcción, es decir, el elemento que no persiste a la derecha en el discurso (Givón, 1980). Las hipótesis se validan con un análisis cualitativo y cuantitativo del cuerpo de datos oral PRESEEA-Buenos Aires (2010-2011).","palabras_clave":"Gramática cognitiva|Español|Preposición de|Semántica"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15110,"idioma_id":4,"titulo":"Population genetic structure and demographic history of Streptococcus mutans (Bacteria: Streptococcaceae)","resumen":"Population genetic studies can contribute to the current knowledge about the epidemiology of pathogens such as Streptococcus mutans, which is one of the most worldwide distributed bacteria associated with human dental caries. In this study, we investigated whether the population genetic structure of the species is clonal or recombinant, and also evaluated the current levels of gene flow, admixed ancestry and the hypothesis of an expansion of the bacteria in the last 10000 years. Strains of S. mutans from Córdoba (Argentina) were obtained, with sequences of the genes aroE, gltA, gyrA and lepC genes being aligned with those of strains from Japan, Thailand and Finland. Most of our statistical analyses performed on the DNA matrix of 193 strains supported the existence of recombination at an inter-gene level. We also estimated the number of genetic clusters through Bayesian analyses, with three genetic clusters being detected in the four countries at different frequencies, and the number of strains with pure or admixed ancestry varying among countries. Argentina revealed 50% admixed strains whereas these types of strains were present in only 8-19% of the other three analysed countries. This result could be associated with the important human migration waves that Argentina experienced, which could have mixed the strains of S. mutans of different geographic origins. The demographic history was obtained using the Extended Bayesian Skyline Plot, and showed an important growth in the effective population size at about 5000 years ago, coincident with the beginning of dispersion of agriculture and the change to a diet rich in carbohydrates.","palabras_clave":"Bayesian inference |MLST |population genetic structure|Recombination Streptococcus mutans"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15113,"idioma_id":4,"titulo":"Removal of recalcitrant organic compounds from an industrial complex effluent by heterogeneous Fenton-type treatment","resumen":"Because of their chemical complexity, industrial chemi-mechanical pulping effluents are evaporated and burned, in spite of the high associated cost involved in these processes. The aim of this study was to remove recalcitrant compounds from this kind of wastewater using a Fenton-type treatment. The main parameters involved in the process and their influence on the results were determined. Homemade catalysts based on CuO, Fe2O3, NiO, and ZnO, supported on &#947;-Al2O3 have been tested for catalytic oxidation, and the CuO\/&#947;-Al2O3 catalysts showed the greatest effect on total organic carbon (TOC) reduction (52.7%). A series of two-level factorial experiments was subsequently applied to evaluate the most favorable range of conditions for CuO\/&#947;-Al2O3 application. The studied variables were hydrogen peroxide concentration ([H2O2], g\/L), active phase content (metal oxide supported on alumina,%), mass of catalyst (metal oxide\/alumina system, g), and reaction temperature (°C). The highest reduction of all parameters was obtained at the superior level of all variables with CuO\/&#947;-Al2O3, achieving reductions of chemical oxygen demand (COD) and TOC between 40 and 50%. Increasing catalyst mass did not produce additional benefit. This variable has a significant effect only on the reduction of aromatic compounds. At its low level, reduction in aromatic content exceeded 80%. Color reduction was influenced only by temperature (maximum reduction of 90%).","palabras_clave":"ADVANCED OXIDATION|CHEMIMECHANICAL PULPING EFFLUENT|FACTORIAL EXPERIMENTAL DESIGN|HETEROGENEUS TYPE FENTON REACTIONS|RECALCITRANT COMPOUNDS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15136,"idioma_id":5,"titulo":"Poder predictivo de la edad y la inteligencia en el desempeño de una tarea de planificación: Torre de Londres","resumen":"La planificación es un concepto clave de la función ejecutiva que permite a las personas generar un plan de acción necesario para la resolución eficaz de un problema con un propósito. Se trata de una capacidad que se desarrolla desde la infancia hasta mediados de la adolescencia y es fundamental para un funcionamiento cotidiano eficaz. El objetivo de este trabajo es determinar el poder predictivo de la edad y la inteligencia sobre la planificación en una muestra de niños de 6 a 13 años de edad. La muestra estuvo conformada por 240 niños divididos equitativamente en cuatro grupos etarios: 6, 8, 11 y 13. Se administró la prueba Torre de Londres y dos pruebas de la Escala de Inteligencia para Niños de Wechsler. Para determinar el grado de asociación entre las variables, se realizaron análisis de correlación, y para determinar el poder predictivo de la edad y la inteligencia sobre la planificación se realizó un análisis de regresión lineal. Los resultados muestran que ambas variables ?edad e inteligencia? se asocian positivamente con el desempeño en Torre de Londres, y que también esas variables tienen un poder predictivo sobre el rendimiento en la tarea de planificación. Los datos permiten concluir que la planificación es una habilidad que se desarrolla a lo largo de la infancia y principios de la adolescencia, y que el nivel intelectual tiene un efecto en la capacidad para generar planes a partir de problemas con un propósito.","palabras_clave":"PLANIFICACIÓN|INTELIGENCIA|DESARROLLO COGNITIVO|TORRE DE LONDRES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15147,"idioma_id":4,"titulo":"Colleters in American Spermacoceae Genera of Rubiaceae, morphoanatomical and evolutionary aspects, and new insights on their function: Long-Life Colleter.","resumen":"Premise of research. The primary goal of this study is to describe the colleters onvegetative and reproductive organs in the Spermacoceae tribe and to characterizetheir morphoanatomy, distribution and some functional and evolutionary aspects.Methodology. The anatomy, development and vascularization of colleters from 28species were studied using standard light and scanning electron microscopy based onfresh and fixed material. Our results are interpreted within the framework of recentmolecular phylogenies.Pivotal results. Standard type colleters were found on stipules, calyx and bracteoles and they were also found on underground buds in five species of Galianthe. Six species have green colleters and two have vascularized colleters. We discuss previously unknown functional aspects based on the Staelia glandulosa colleters and propose a new term: long-lived colleters.Conclusions. This paper describes the anatomy of colleters in the Spermacoceae tribeof the family Rubiaceae in detail. The presence of underground colleters in Galianthe grandifolia is confirmed and extended to other species of the genus. Vascularization is recorded for the first time in colleters of Mitracarpus and Staelia. This study provides data about the type, distribution and anatomy of colleters in Spermacoceae, contributing important information for ongoing phylogenetic studies in the tribe. The proposal of a new functional type of colleter based on anatomical, morphological and ecological aspects, named long-lived colleter, reflects the need to perform further comprehensive studies based on multidisciplinary approaches.","palabras_clave":"RUBIACEAE|COLLETERS|SPERMACECEAE|GLANDULAR"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15152,"idioma_id":4,"titulo":"Impact of residue addition on soil nitrogen dynamics in complex agroecosystems","resumen":"Soil nitrogen (N) is one of themost important nutrients for plant productivity and microbial activity in terrestrialecosystems. However, soil N is also readily affected by land management practices, influencing N2O emissions.This study assessed N dynamics in soil from different crop systems including a 1:2 (one row of maize and tworows soybean) and 2:3 (two rows of maize and three rows of soybean) intercrop and a maize and soybeansole crop as a result of residue addition frommaize or soybeans. This was achieved through a 140-day incubationstudy using &#948;15N natural abundance. The effect of residue addition on soil TN was greater than its influence oncrop systems when compared to treatments with no residue addition (Cont). The influence of residue additionon intercrops was most readily observed in the fractionated soil. Light fraction N (LF-N) and soil microbial biomassN (SMB-N) were significantly greater (p b 0.05) in the intercrops than in the sole crops. Residue amendedtreatments were significantly (p b 0.05) depleted in &#948;15N-TN, &#948;15N-LF and &#948;15N-SMB compared to Cont treatments.The &#948;15N-SMBwas significantly enriched (p b 0.05) compared to that of the residue, TN and LF-N. Residueamended treatments had significantly lower (p b 0.05) N2O emissions than Cont treatments.However,N2Oemissionswere not significantly different (p b 0.05) between soybean and maize amended treatments, nor betweenintercrops and sole crops. Our results demonstrate that the addition of contrasting residue types influencedshort-term N dynamics in intercrops differently than sole crops.©","palabras_clave":"FREE LIGHT FRACTION NITROGEN|INTERCROPS|N2O EMISSIONS|SOIL MICROBIAL BIOMASS NITROGEN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15154,"idioma_id":4,"titulo":"Early genetic consequences of defaunation in a large-seededvertebrate-dispersed palm (Syagrus romanzof&#64257;ana)","resumen":"Plant populations are seriously threatened byanthropogenic habitat disturbance. In particular, defaunation may disruptplant-disperser mutualisms, thus reducing levels of seed-mediated gene flow andgenetic variation in animal-dispersed plants. This may ultimately limit theiradaptive potential and ability to cope with environmental change. Tropicalforest remnants are typically deprived of medium to large vertebrates uponwhich many large-seeded plants rely for accomplishing effective seed dispersal.Our main goal was to examine the potential early genetic consequences of theloss of large vertebrates for large-seeded vertebrate-dispersed plants. Wecompared the genetic variation in early-stage individuals of the large-seededpalm Syagrus romanzoffiana betweencontinuous protected forest and nearby partially defaunated fragments in theAtlantic Forest of South America. Using nine microsatellites, we found lowerallelic richness and stronger fine-scale spatial genetic structure in thedisturbed area. In addition, the percentage of dispersed recruits aroundconspecific adults was lower, although not significantly, in the disturbed area(median values: 0.0% vs. 14.4%). On the other hand, no evidence of increasedinbreeding or reduced pollen-mediated gene flow (selfing rate and diversity ofpollen donors) was found in the disturbed area. Our findings are stronglysuggestive of some early genetic consequences resulting from the limitation incontemporary gene flow via seeds, but not pollen, in defaunated areas.Plant-disperser mutualisms involving medium-large frugivores, which areseriously threatened in tropical systems, should therefore be protected towarrant the maintenance of seed-mediated gene flow and genetic diversity inlarge-seeded plants.","palabras_clave":"fragmentation|defaunation|genetic structure|seed dispersal"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15175,"idioma_id":4,"titulo":"Generation and correlation of orthogonal complementary pairs of sequences of lengths 2 N 10 M 26 P based on an improved multilevel complementary sequences approach","resumen":"Binary complementary pairs of sequences of lengths 2N10M26P posses some interesting properties for their application in signal detection in noisy channels. Nonetheless, they have not been broadly used because of their greater processing requirements as compared with binary complementary sequences with L&nbsp;=&nbsp;2N. The present work introduces a new approach for generation and correlation of binary complementary pairs of sequences of length 2N10M26P that reduces the number of required operations. The proposed algorithm allows not only to optimize the number of arithmetic operations but also to correlate two orthogonal complementary pairs simultaneously with the use of a single architecture. Due to the fact that multilevel complementary sequences algorithms are used to generate and correlate binary complementary sequences of length 2N10M26P, the aforementioned algorithms are also improved. The proposal is theoretically proved and its arithmetic efficiency is assessed by comparing the number of operations with that of previously published architectures. Copyright &copy; 2017 John Wiley &amp; Sons, Ltd.","palabras_clave":"Complementary Sequences|Efficient Algorithms|Generation|Multilevel"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15194,"idioma_id":4,"titulo":"Microbial oxidation of refractory gold sulfide concentrate by a native consortium","resumen":"A defined mesophilic consortium including an iron oxidizing bacterium and a sulfur oxidizing bacterium was constructed to evaluate its ability for bioleaching a flotation concentrate from Andacollo mine in Neuquén, Argentina. Experiments were performed in shake flasks with a pulp density of 10% (w\/v), using a basal salt medium containing ferrous iron at pH 1.8. The leaching solutions were analyzed for pH, redox potential (using specifics electrodes), ferrous iron (by UV-Vis spectrophotometry) and metal concentrations (by atomic absorption spectroscopy). The results showed that the consortium was able to reduce the refractory behavior of the concentrate, allowing 91.6% of gold recovery; at the same time, high dissolution of copper and zinc was reached. These dissolutions followed a shrinking core kinetic model. According to this model, the copper solubilization was controlled by diffusion through a product layer (mainly jarosite), while zinc dissolution did not show a defined control step. This designed consortium, composed of bacterial strains with specific physiological abilities, could be useful not only to optimize gold recovery but also to decrease the leachates metallic charge, which would be an environmental advantage.","palabras_clave":"BIOOXIDATION|REFRACTORY GOLD|NATIVE CONSORTIUM|KINETIC ANALYSES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15204,"idioma_id":5,"titulo":"La complementariedad de procesos opuestos.   Santa Fe-Paraná en el inicio de la consolidación metropolitana","resumen":"La Región Metropolitana Santa Fe-Paraná, se presenta como un ámbito urbano-rural, que habiendo sobrepasado el millón de habitantes, reconoce como particularidad la duplicación de su ciudad central en dos núcleos  urbanos -Paraná y Santa Fe-, localidades aglomeradas, ciudades perimetrales y pequeñas localidades en el anillo interior definido.En el marco de la investigación en curso se vienen desarrollando estudios que enfocan distintos aspectos de esta conformación urbano-territorial. En este trabajo se presenta un estudio de su dinámica, en función de la disponibilidad de los resultados del Censo 2010.En términos de resultados, este análisis socio-espacial posibilita detectar la evolución de una serie de procesos que ameritan ser profundizados, como la continuidad de un tránsito hacia un modelo de organización con indicios de la integración de nuevas áreas a la aglomeración y, a la vez, la consolidación de algunos subcentros metropolitanos, con capacidad de influencia en la estructura integral.","palabras_clave":"REGIÓN METROPOLITANA|SANTA FE-PARANÁ|ANÁLISIS TERRITORIAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15222,"idioma_id":4,"titulo":"Throat Carriage Rate and Antimicrobial Resistance of Streptococcus pyogenes In Rural Children in Argentina","resumen":"Objectives: Determine the prevalence of asymptomatic carriers of GAS in children from a rural community and investigate the association between episodes of acute pharyngitis and carrier status.Methods: observational, prospective and transversal study. Throat swabs were collected from September to November 2013 among 5-13 years old children from a rural community (Maria Ignacia-Vela, Argentina). Phenotypical characterization of isolates was performed by conventional tests. Antimicrobial susceptibility was assayed for penicillin, tetracycline, chloramphenicol, erythromycin and clindamycin (disk diffusion) Minimum Inhibitory Concentration was determined for penicillin, cefotaxime, tetracycline and erythromycin.  Results: Carriage of &#946;-hemolytic streptococci has been detected (18.1%): Streptococcus pyogenes (n: 18) followed by S. dysgalactiae ssp. equisimilis (n: 5). Highest percentage of GAS was found in 8-10 years old children. No significant association between the number of episodes of acute pharyngitis suffered in the last year and the carrier state was detected (p>0.05). Tetracycline resistance (55.5%) and macrolides resistant phenotypes (11.1%) were observed. Penicillin, cefotaxime and chloramphenicol resistance was not expressed in any streptococcal isolate.Conclusions: The present study has proven a significant throat carriage of GAS and the presence of Group C streptococci (S. dysgalactiae ssp. equisimilis) in an Argentinian rural population. These results point out the need of a continuous surveillance of GAS and non-GAS carriage as well as the antimicrobial resistance in a highly susceptible population, such as school aged rural children. An extended surveillance program including school aged children from different cities should be considered to estimate the situation in Argentina.","palabras_clave":"STREPTOCOCCUS PYOGENES|CARRIAGE|ANTIMICROBIALS|RESISTANCE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15229,"idioma_id":4,"titulo":"Light wavelength distribution effects on the growth rate of Scenedesmus quadricauda","resumen":"One of the main problems posed by the growth of microalgae is to achieve efficient lighting in the photo-bioreactors (PBRs). Poor distribution of light within the culture can cause that real productivity achieved in large scale reactors is two to three orders of magnitude lower than those achievable with better distributions. Physical and mathematical modeling is a valuable tool for the design and optimization of these type of bioprocesses. In this study, kinetic models of the growth rate of Scenedesmus quadricauda and of the production rate of chlorophylls, were proposed. These models consider the influence of the radiation wavelength composition and of monochromatic light density on microalgal cultures. The parameters of the kinetic model were regressed from experimental data by using a main computer program based on a Genetic Algorithm (GA), supported by a home-built subroutine that consists on a Monte Carlo (MC) simulator for predicting the values of the relevant properties of the radiation field, which was developed in previous work. With the proposed kinetic models, it was possible to achieve the correct simulation of different microalgal cultures carried out in two types of PBRs, illuminated with light of different wavelength composition provided by different light emitting diodes (LEDs) arrangements.","palabras_clave":"MICROALGAE|RADIANT FIELD|PHOTOBIOREACTORS| LIGHT EMITTING DIODE|MONTE CARLO|GROWTH KINETIC MODEL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15231,"idioma_id":5,"titulo":"Evidencias sobre una nueva especie del género Dirofilaria en perros de Neuquén, Argentina","resumen":"Resumen: La dirofilariasis canina en Argentina se extiende desde la provincia de Buenos Aires hacia el norte. En todos los casos documentados, el agente etiológico es el gusano del corazón del perro, Dirofilaria immitis, única especie del género identificada como causal de infecciones naturales autóctonas en el país. En este estudio, se presentan evidencias morfológicas, serológicas y moleculares de la infección de otra especie del género Dirofilaria en 8 perros de la ciudad de Neuquén, en el extremo norte de la Patagonia. Las microfilarias observadas tuvieron una media de 370 mm de largo y 7,1 mm de ancho. Las secuencias obtenidas mostraron homologías inferiores al 95 % con otras secuencias de filáridos reportadas en el GenBank.","palabras_clave":"Filaria|Perro|Patagonia|Argentina"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15342,"idioma_id":5,"titulo":"Vulnerabilidad y riesgo en la Producción Hortícola. El caso del Cinturón Verde de Córdoba, Argentina","resumen":"El Cinturón Verde de la Ciudad de Córdoba (cvcc) en Argentina está marcado por la reproducción de relaciones desiguales, la informalidad y débil institucionalidad para la regulación de la exposición laboral a plaguicidas. Objetivo: visibilizar situaciones de vulnerabilidad y riesgo como construcción social-material, que afecta a quienes trabajan en unidades productivas hortícolas del cvcc, asociadas a condiciones de vida y trabajo. Metodología: estudio epidemiológico descriptivo correlacional. Se conformó una muestra de 101 trabajadores \/ productores, con un nivel de confianza del 95%. Se obtuvo información mediante encuesta, indagando aspectos sociodemográficos, condiciones de vida, prácticas laborales, cultivos, estilos de vida y condiciones de salud del productor \/ trabajador y su familia. Se calcularon estadísticas descriptivas, se usó xi2 como test de hipótesis y análisis factorial de correspondencias múltiples. Resultados: encontramos diferencias en la situación de vulnerabilidad y riesgo en grupos de propietarios, arrendatario-medieros. En el primero se objetiva el riesgo vinculado a la falta de cuidados al usar plaguicidas; en el segundo se configuran situaciones de vulnerabilidad asociadas a la reproducción de relaciones desiguales. La comprensión de la vulnerabilidad y el riesgo desde la condición laboral, permite precisar aspectos de la exposición a plaguicidas a ser contemplados en programas de salud.","palabras_clave":"CONDICIÓN LABORAL|VULNERABILIDAD|RIESGO|EXPOSICION|HORTICULTURA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15379,"idioma_id":4,"titulo":"Do species' strategies and type of stress predict net positive effects in an arid ecosystem?","resumen":"A proposed refinement to the stress-gradient hypothesis requires consideration of the strategies of the interacting species and the characteristics of the stress factors. While the strength and direction of these interactions can be predicted for different ecosystems, this idea remains largely untested in the field. We performed a manipulative field experiment complemented with a descriptive study to test the predictions in a natural setting that represents the extreme end of a precipitation gradient. There, wind driven desiccation and water availability are the main stressors (non-resource and resource-based stresses, respectively). We evaluated the interaction between the shrub and grasses that are dominant in the Patagonian steppe. The species had differences in morpho-functional traits and drought tolerance that fit into the C?S axis of Grime´s strategies. We experimentally separated root zones to limit direct competition for soil moisture and reduce the resource-based stress on grasses. We also manipulated the distance to shrubs to evaluate non-resource stress amelioration by canopies (e.g., sun and wind) on grasses. Finally, we evaluated the distribution of naturally established C and S grasses in the neighborhood of C and S shrubs to infer process-pattern relationships. Our growth data coincide to a large degree to the predictions. We found positive effects on the growth of beneficiaries when stress was non-resource based and when strategies differed (i.e., Cshrub?Sgrass and Sshrub?Cgrass). We also found strong negative effects when the abiotic stress was driven by water, particularly on C grasses. Additionally, shrubs only increased the survival of grasses when strategies differed (i.e., Cshrub?Sgrass and Sshrub?Cgrass). Our manipulative and descriptive study supported previous results that showed that stress-tolerant species are important for the persistence of competitive species at high stress. While the applicability and generality of these predictions remains to be tested with more field experiments, some ecological factors, such as stress types and species traits, can explain much of the variation in how dominant shrubs and grasses interact in this extreme arid environment. Moreover, this framework could be extended to specifically test the importance of facilitation under different levels of stress.","palabras_clave":"ARID ENVIRONMENTS|FACILITATION|PLANT-PLANT INTERACTIONS|SPECIES TRAITS|STRESS GRADIENT HYPOTHESIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15385,"idioma_id":5,"titulo":"Sexo y edad en la experiencia censal moderna","resumen":"A pesar de las sospechas sobre el proceso de construcción de datos, existe todavía hoy un vacío en lo que respecta al estudio concreto de los resultados del censo de 2010 en la Argentina. El artículo analiza, a nivel del total del país, cuáles fueron las limitaciones y alcances de la información disponible y publicada del último censo de población de la Argentina en lo que respecta a dos de las variables básicas y fundamentales para las ciencias sociales: sexo y edad. A partir de la comparación con los censos modernos y a través del uso de técnicas demográficas, se muestra que la declaración de la edad y sexo logró altos niveles de calidad. El desempeño del censo 2010 frente al anterior no fue sustantivamente superior, cuando sólo se preguntó solamente por la edad en años cumplidos; a pesar de ello la doble pregunta presenta distintas ventajas metodológicas. Por su parte, la pregunta sobre el sexo mantiene ambigu&#776;edades sobre su definición, lo que implica la necesidad de revisitar su definición.","palabras_clave":"CENSO 2010|SEXO|EDAD|EVALUACIÓN DE CALIDAD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15386,"idioma_id":5,"titulo":"La mortalidad de las cohortes en la ciudad de Buenos Aires","resumen":"Las investigaciones acerca de los cambios en los niveles de mortalidad mostraron que desde fines del XIX hasta principios del siglo XXI la esperanza de vida al nacer en la Ciudad de Buenos Aires siguió una tendencia ascendente, aumentado de 32 años en 1855 a 77 en 2009. A pesar del conocimiento acumulado sobre este proceso, su exploración fue casi exclusivamente de forma transversal. El objetivo de este artículo es analizar los cambios en los niveles de mortalidad de cohortes reales en la Ciudad de Buenos Aires, desde fines del siglo XIX. Las esperanzas de vida al nacer de periodo y de cohorte revelaron significativas mejoras y consecuentes diferencias a favor de las últimas; estas brechas se hicieron mayores a medida que desciende la mortalidad, hasta la cohorte de 1958. Los datos construidos permiten reexaminar, desde un punto de vista comparativo y longitudinal, probables trayectorias de las cohortes en el pasado e hipotéticos escenarios futuros de mortalidad de las cohortes más recientes y reabrir preguntas acerca del proceso de transición demográfica, y su corolario, el envejecimiento, así como sobre probables escenarios futuros y características del crecimiento de la población en la Ciudad.","palabras_clave":"MORTALIDAD|CIUDAD DE BUENOS AIRES|TABLAS DE VIDA DE COHORTE|ESPERANZA DE VIDA AL NACER"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15389,"idioma_id":4,"titulo":"Study of the TP53 codon 72 polymorphism in oral cancer and oral potentially malignant disorders in Argentine patients","resumen":"The aim of this work was to evaluate the prevalence of TP53Arg72Pro mutations and their possible relationship with oral carcinoma and oral potentially malignant disorders in Argentine patients. A cross-sectional study was performed on 111 exfoliated cytologies from patients with oral cancer (OC), oral potentially malignant disorders (OPMD) and controls. The TP53Arg72Pro mutations were determined using conventional PCR. We evaluated univariate and multivariate study variables, setting p < 0.05. We found: (a) a low frequency of Pro72 variant in control group and a high frequency in OC and OPMD, as well in OC and oral leukoplakia (OL) diagnosis; (b) multivariate association among the TP53CC genotype and females over 45 years with no tobacco nor alcohol habits with oral lichen planus pathology; (c) multivariate association between the TP53GC genotype and males with alcohol and tobacco habits and OC and OL pathologies. Our results showed that the wild-type Arg72variant was related to control patients and Pro72variant was related to OC and OPMD, in Argentine patients.","palabras_clave":"POLYMORPHISM|CANCER"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15392,"idioma_id":5,"titulo":"Cada quien atiende su juego. Un estudio acerca de las alianzas electorales en la pelea por la cámara baja en Argentina (1983-2013)","resumen":"La integración entre diferentes niveles de las organizaciones partidarias tiene importantes consecuencias para el funcionamiento del sistema político multinivel. Las alianzas electorales es uno de los elementos en los cuales es posible evidenciar la integración de los partidos. Cuando el nivel local de las organizaciones cuenta con autonomía para armar sus propias alianzas electorales para cargos legislativos nacionales, los compañeros de dichas alianzas pueden diferir de aquellos con los que el partido nacional hace alianza para la competencia por la Presidencia.Este artículo encuentra evidencia acerca de que el grado de congruencia aliancista de los partidos argentinos ha ido bajando entre 1983 y 2013 en la competencia por las bancas de Diputados Nacionales. Aquí se plantea que cuando la elección de Presidente se realiza de manera concurrente con de la de Diputados Nacionales, la congruencia aliancista de los partidos entre los distintos distritos, tiende a aumentar. Y lo mismo ocurre cuando el sistema de partidos se encuentra más nacionalizado.","palabras_clave":"ALIANZAS|COALICIONES|DIPUTADOS|PARTIDOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15438,"idioma_id":5,"titulo":"'El enemigo en casa'. La inmigración Latinoamericana como amenaza a la identidad cultural estadounidense: La identidad desde las Relaciones Internacionales.","resumen":"Este trabajo forma parte de mi tesis de doctorado (2015) y se encuentra determinada desde unaperspectiva teórica sostenida desde el desarrollo constructivista a través de un abordaje descriptivoexplicativo.¿Cómo se establece y formula la percepción en los diferentes actores sociales?, o ¿Cómolos diversos actores se expresan sobre esta inmigración? Nos lleva a preguntarnos, cómo y por quéalgunos flujos migratorios son percibidos como amenaza a la identidad cultural, depende del lugar deacogida y cómo ésta se define a sí misma. En general nos encontramos con una serie de principiosque van desde establecer a quienes se admiten; por qué se los admite; y a qué tipo de migración seacepta. Los factores culturales e identitarios han sido poco discutido por las teorías tradicionales, estose debe, a su dificultad en cuanto a su cuantificación y, a que no formaban parte de la alta política. Enla década del noventa Huntington propuso una descripción simplificada de la realidad, sosteniendoque nos encontrábamos en una nueva etapa, donde los factores culturales serían los determinantesdel sistema internacional. La teoría del ?choque de las civilizaciones? determinaba la identificación del?enemigo fuera de casa?. En su último libro ¿Quiénes somos? convierte esta teoría en virtud deseñalar al ?enemigo en casa?, la determinación de un síntoma, un discurso que sigue la lógica del?chivo expiatorio?. De esta manera este término ha sido utilizado como sinónimo de excusa, principalargumento, o pantalla, entender lo valioso de un discurso argumentando y convalidando actitudespara quienes desean emprender una campaña contra otros, es decir, el juego de la ?CartaNacionalistas?, el todo vale en defensa de nuestra supuesta identidad.","palabras_clave":"IDENTIDAD|CONSTRUCTIVISMO|CHIVOEXPIATORIO|RELACIONESINTERNACIONALES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15458,"idioma_id":4,"titulo":"Valorization of Different Wastes and Their Use for the Design of Multifunctional Eco-catalysts","resumen":"The desire to protect the environment for future generations has led to the reutilization of all recoverable and recyclable wastes. Consequently, different residues from various sources were collected to make mixed compounds to be used as catalyst supports. Such wastes included sand and cement from the building industry, nonreturnable glass bottles, and used tires. The synthesized supports were impregnated with molybdophosphoric acid, a heteropolyacid with Keggin structure, and characterized by potentiometric titration, optical microscopy, SEM?EDS, and textural property analyses. The bifunctional properties of the new catalysts were evaluated in two relevant transformations in green conditions: (i) the selective oxidation of sulfides to sulfoxides using a green oxidant such as tert-butyl hydroperoxide, and (ii) the multicomponent synthesis of 3,4-dihydropyrimidinones (Biginelli reaction, catalyzed in acid media).","palabras_clave":"Waste valorization|Catalysts|Heteropolyacids|3,4-Dihydropyrimidinones|Sulfide oxidation|Green Chemistry"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15467,"idioma_id":4,"titulo":"First Miocene record of Akaniaceae in Patagonia (Argentina): a fossil wood from the early Miocene Santa Cruz formation and its palaeobiogeographical implications","resumen":"Today, Akaniaceae are confined to south-eastern Queensland, north-eastern New South Wales, south-easternChina, and northern Vietnam. Akanioxylon santacrucensis gen. and sp. nov. is described as the first fossil wood ofAkaniaceae from the early Miocene Santa Cruz Formation (c. 18?16 Ma; Burdigalian) on the Atlantic coast of SantaCruz Province, Argentina. The diagnostic features are growth rings inconspicuous, with most latewood vessels onlyslightly narrower than earlywood vessels; diffuse porous wood; mainly solitary vessels, occasionally radial or tangentialmultiples and clusters; mainly simple, occasionally reticulate and rarely scalariform with many interconnectionsbetween bars perforation plates; bordered, minute to small intervessel pits; axial parenchyma scanty paratrachealand apotracheal diffuse; vessel-ray parenchyma pits with much reduced borders to apparently simple; vessel-axialparenchyma pits scalariform or transitional; mainly multiseriate (four to six cells wide) and rare uniseriate rays,heterocellular, occasionally crystals in ray cells; septate and non-septate fibres with simple to minutely borderedpits. These features resemble the extant Akania Hook.f. and Bretschneidera Hemsl. The eco-anatomical analysissuggests that this fossil wood grew under temperate to warm-temperate and semi-arid climatic conditions. Thisrecord of Akania\/Bretschneidera-like wood in South America reinforces the existence of an old relationship with theAustralasia flora. The discovery of Akaniaceae in the Santa Cruz Formation extends the record of the taxon in SouthAmerica c. 30 Ma and 10°S in latitude and suggests that the family was widespread in Patagonia as a component offorests developed in a frost-free humid biome in South American at mid to high latitudes.","palabras_clave":"early Miocene fossil wood ? |high latitudes ? |Santa Cruz Formation ? |South America"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15491,"idioma_id":4,"titulo":"Single ionization and capture cross sections from biological molecules by bare projectile impact","resumen":"Abstract. We report calculations on single differential and total cross sections for single ionization and single electron capture from biological targets, namely, vapor water and DNA nucleobasese molecules, by bare projectile impact: H + , He 2+ , and C 6+ . They are performed within the Continuum Distorted Wave? Eikonal Initial State approximation and compared to several existing experimental data. This study is oriented to the obtention of a reliable set of theoretical data to be used as input in a Monte Carlo code destined to micro- and nano- dosimetry.","palabras_clave":"IONIZATION|CAPTURE|COLLISIONS|BIOMOLECULES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15492,"idioma_id":4,"titulo":"Degradation alternatives for a commercial fungicide in water: biological, photo-Fenton and coupled biological-photo Fenton processes","resumen":"Imazalil (IMZ) is a widely used fungicide for the post-harvest treatment of citrus, classified as Blikely to be carcinogenic in humans^ for EPA, that can be only partially removed by conventional biological treatment. Consequently,specific or combined processes should be applied to prevent its release to the environment. Biological treatment with adapted microorganism consortium, photo-Fenton, and coupled biological photo-Fenton processes were tested as alternatives for the purification of water containing high concentrationof the fungicide and the coadjutants present in the commercial formulation. IMZ-resistant consortium with the capacity to degrade IMZ in the presence of a C-rich co-substrate was isolated from sludge coming from a fruit packagingcompany wastewater treatment plant. This consortium was adapted to resist and degrade the organics present in photoFenton-oxidized IMZ water solution. Bacteria colonies from the consortia were isolated and identified. The effect of H2O2 initial concentration and dosage on IMZ degradation rate, averageoxidation state (AOS), organic acid concentration, oxidation, and mineralization percentage after photo-Fenton process was determined. The application of biological treatment to the oxidized solutions notably decreased the totalorganic carbon (TOC) in solution. The effect of the oxidation degree, limited by H2O2 concentration and dosage, on the percentage of mineralization obtained after the biological treatment was determined and explained in terms of changesin AOS. The concentration of H2O2 necessary to eliminate IMZ by photo-Fenton and to reduce TOC and chemical oxygen demand (COD) by biological treatment, in order to allow the release of the effluents to rivers with different flows, was estimated.","palabras_clave":"Imazalil|Bioremediation|Photo Fenton|Coupled Treatment"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15535,"idioma_id":5,"titulo":"El espacio y los recursos: análisis arqueo faunístico mediante SIG en los distintos ambientes de la provincia de Santa Fe (Argentina)","resumen":"El objetivo de este trabajo es evaluar el uso de los recursos faunísticos que realizaron las poblaciones humanas que habitaron los distintos ambientes de la provincia de Santa Fe, particularmente establecer una comparación entre las ecoregiones del Chaco Húmedo, el Espinal y Delta e Islas del Paraná vs. la llanura pampeana durante el Holoceno. Para ello se compila información zooarqueológica publicada proveniente de 13 contextos de 12 sitios arqueológicos los cuales fueron analizados por diferentes equipos de investigación. Para llevar a cabo el análisis de la composición de los conjuntos en términos espaciales se implementa el uso de un Sistema de información geográfica (SIG). Esta herramienta facilita la comparación entre la representación de los distintos taxa a nivel espacial en una zona que presenta diferencias ecológicas que pueden haber redundado en un uso diferencial de los recursos.","palabras_clave":"zooarqueología|SIG|ambientes de la provincia de Santa Fe"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15550,"idioma_id":5,"titulo":"Cuando la carrera no rinde. Las consecuencias de la convergencia salarial de trabajadores white y blue collar en grandes empresas en la Argentina","resumen":"En este trabajo, analizamos las consecuencias del solapamiento salarial entre los mandos medios y los trabajadores sindicalizados que se viene produciendo en la Argentina desde hace algunos años. Nos preguntamos acerca de la reticencia de los managers a sindicalizarse para defender sus intereses. Esto nos lleva a indagar la relación entre el peronismo y las clases medias. Este artículo es el producto de reflexiones basadas en una investigación en curso sobre cuadros de conducción de grandes empresas de diferentes sectores de la economía argentina y con diversos orígenes de sus capitales. La estrategia metodológica es cualitativa y se basa en entrevistas en profundidad semiestructuradas.","palabras_clave":"MANAGERS|CARRERA|SOLAPAMIENTO SALARIAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15553,"idioma_id":4,"titulo":"Spectroelectrochemical analysis of the controlled modification of the surface of HOPG? E. A. Franceschini, G. I. Lacconi*  Appl. Surf. Scie 400 (2017) 254-261. DOI: 10.1016\/j.apsusc.2016.12.115","resumen":"In situ Raman spectroscopy is used to characterize the changes induced by electrochemical oxidation and silver electrodeposition at the step-edge and terrace sites of highly-oriented pyrolytic graphite (HOPG) surfaces. Ag crystallites are observed to become preferentially deposited onto previously oxidized step edges, thereby leading to an enhancement of the Raman active modes of the HOPG surface. Ex situ Raman spectra recorded after HOPG oxidation exhibit clear differences for both terrace and step-edge areas of the surface. An increase of D and D&#305;´ band intensity and two well-defined D-band contributions, D1 (at 1324 cm&#8722;1) and D2 (at 1344 cm&#8722;1), are the main features observed after oxidation. This effect can be correlated with the presence of step-edge sites on the surface, and are found to be strongly dependent on the pH of the solution used in the surface electrochemical oxidation experiments.","palabras_clave":"Silver electrodeposition |Electrochemical oxidation|SERS|HOPG step edges"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15594,"idioma_id":5,"titulo":"Efecto de la variabilidad climática sobre el estado de la vegetación y la cobertura de agua en una cuenca de clima templado (Argentina)","resumen":"El área de estudio se encuentra en el sur de la provincia de Buenos Aires (Argentina) y forma parte de la región pampeana Argentina. Se caracteriza por el predominio de un clima templado. El objetivo de este trabajo fue cuantificar los efectos de los eventos climáticos extremos en el estado de la vegetación y la extensión del área cubierta por agua, en una cuenca hidrográfica de clima templado (cuenca del arroyo Napostá Chico). El período de estudio fue 2000-2013. La metodología incluyó el análisis de serie de datos del Índice Estandarizado de Precipitación y Evapotranspiración (SPEI) a escala 1, 3 y 12 meses, para la detección de eventos climáticos extremos. Mediante interpretación visual de imágenes satelitales, se determinaron las diferentes coberturas de la cuenca y se calculó el Índice de Vegetación de Diferencia Normalizada (en inglés, NDVI). Además, se delinearon  los cuerpos de agua del área de estudio mediante procesamiento digital de imágenes satelitales Landsat 5 TM y 7 ETM+ correspondientes a los eventos extremos definidos mediante la aplicación del SPEI. Los mismos fueron definidos para 2001 y 2004 (eventos húmedos), 2008 y 2009 (eventos secos) y 2007 (evento normal). El estado de la vegetación así como también las extensiones cubiertas por los cuerpos de agua, presentaron variaciones a lo largo de los diferentes eventos climáticos extremos. La vulnerabilidad climática de la cuenca y el conocimiento de los eventos de precipitación extremos es fundamental para la gestión de los recursos hídricos y de las actividades agroeconómicas que allí se desarrollan.","palabras_clave":"VARIABILIDAD CLIMATICA|SPEI|NDVI"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15610,"idioma_id":4,"titulo":"Integrated process for the purification and immobilization of the envelope protein domain III of dengue virus type 2 expressed in Rachiplusia nu larvae and its potential application in a diagnostic assay","resumen":"Dengue incidence has grown dramatically in the last years, with about 40% of the world population at risk of infection. Recently, a vaccine developed by Sanofi Pasteur has been registered, but only in a few countries. Moreover, specific antiviral drugs are not available. Thus, an efficient and accurate diagnosis is important for disease management. To develop a low-cost immunoassay for dengue diagnosis, in the present study we expressed the envelope protein domain III of dengue virus type 2 in Rachiplusia nu larvae by infection with a recombinant baculovirus. The antigen was expressed as a fusion to hydrophobin I (DomIIIHFBI) to easily purify it by an aqueous two-phase system (ATPS) and to efficiently immobilize it in immunoassay plates. A high level of recombinant DomIIIHFBI was obtained in R. nu, where yields reached 4.5 mg per g of larva. Also, we were able to purify DomIIIHFBI by an ATPS with 2% of Triton X-114, reaching a yield of 73% and purity higher than 80% in a single purification step. The recombinant DomIIIHFBI was efficiently immobilized in hydrophobic surface plates. The immunoassay we developed with the immobilized antigen was able to detect IgG specific for dengue virus type 2 in serum samples and not for other serotypes.","palabras_clave":"RACHIPLUSIA NU LARVAE|RECOMBINANT FUSION PROTEIN|HYDROPHOBIN|DOMAIN III"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15626,"idioma_id":4,"titulo":"Effect of steviosides and potassium sorbate on the growth and thermal inactivation of Zygosaccharomyces bailii in acidified model aqueous systems","resumen":"Zygosaccharomyces bailii growth and thermal inactivation curves were obtained in acidified aqueous systems, simulating low sugar products. Growth curves were fitted with Gompertz equation, while thermal inactivation curves were modeled using Baranyi equation. The parameters of the models were estimated and the effect of steviosides (EE) and potassium sorbate (KS) on the growth and survival of Z. bailii was established. The addition of KS decreased Z. bailii growth rate and increased its inactivation rate. The presence of EE promoted Z. bailii growth and protected yeast from thermal treatment. The joint use of KS and EE decreased the growth and nullified the protective effect of the sweetener on thermal inactivation. Results allow the selection of the appropriate concentrations of EE and KS to ensure the microbiological stability of evaluated systems and contribute to the development of low sugar products.","palabras_clave":"STEVIOSIDES|POTASSIUM SORBATE|ZYGOSACCHAROMYCES BAILII"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15631,"idioma_id":5,"titulo":"Políticas educativas y condiciones de trabajo de los profesores de secundaria de la Provincia de Buenos Aires (2004-2014)","resumen":"Este estudio tiene como objetivos analizar la normativa educativa nacional y provincial del período 2004-2014 y su impacto en las condicioneslaborales de los docentes, y el perfil y las condiciones laborales básicas de los ocupados en la Rama de Enseñanza durante eseperíodo, en la provincia de Buenos Aires.El estudio utiliza el análisis documental y un abordaje de tipo cuantitativo basado en la información recogida por la Encuesta Permanentede Hogares (EPH) durante los años 2004, 2009 y 2014, en los aglomerados urbanos del Conurbano Bonaerense, Mar del Plata, La Plata yBahía Blanca. El análisis documental permite considerar el impacto de ciertos aspectos de la normativa educativa para el nivel secundariosobre las condiciones laborales de los docentes. Por su parte, del análisis de la información cuantitativa surgen, entre otras cosas, elincremento importante del número de ocupados en la Rama de Enseñanza, la mejora sufrida por los ingresos promedio de los ocupadosen la Rama de Enseñanza, el aumento de las horas promedio de trabajo de los docentes y una disminución de la precarización del empleodocente durante los primeros años del período considerado. Persisten como problemas a resolver, los relativamente altos porcentajes dedocentes que trabajan en varios establecimientos y los que tienen una importante carga laboral semanal, tomando en cuenta que otraimportante cantidad de horas son dedicadas a la preparación de clases, actualización de contenidos, corrección de trabajos y exámenesde los alumnos, etc. Esto resultados serán profundizados y enriquecidos, en una segunda etapa, con un estudio cualitativo.","palabras_clave":"POLITICAS EDUCATIVAS|EDUCACIÓN SECUNDARIA|DOCENTES |CONDICIONES LABORALES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15645,"idioma_id":5,"titulo":"DIALÉCTICA, TEOLOGÍA, ONTOLOGÍA Roscelino y Anselmo","resumen":"RESUMENEste artículo presenta una relectura de la Epistola de incarnatione verbi anselmiana exponiéndolacomo una interpretación textual y doctrinal efectuada por Anselmo sobre la sentencia de Roscelin deCompiègne. Jalonada por tres momentos: oír, entender y responder. Oír se aplica al texto literal de lasentencia de Roscelino en la versión condicional de la Epistola de incarnatione verbi y en la epístola 128por una parte, y en la versión disyuntiva excluyente de las epístolas 129 y 136 por la otra. Entender exigela experiencia del creyente en la palabra encarnada. Responder refuta la tesis de Roscelino.Palabras clave: cosa - encarnación - persona.","palabras_clave":"Encarnación|Persona|Cosa|Trinidad"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15658,"idioma_id":4,"titulo":"Clearance of tritrichomonas foetus in experimentally infected heifers protected with vaccines based on killed T. foetus with different adjuvants","resumen":"Tritrichomonas foetus is a flagellated protozoan that causes a sexually transmitted disease in cattle. Trichomonosis is characterized by early abortions, subfertility and a significant decrease in productivity. Vaccine preparations containing whole T. foetus can reduce the time of residence of the pathogen in the host cervix after experimental infection. Here, T. foetus vaccines prepared with different adjuvants were tested, in parallel with a commercial vaccine, for their efficacy to clear the infection. The median time for clearance of infection was 69days in non-immunized animals, 55days in animals treated with aluminum hydroxide, 41days with oil-in-water or saponin based vaccines or with a commercial vaccine and 27days in animals treated with saponin plus aluminum hydroxide. A slight increase in the risk of T. foetus clearance from the genital tract was found with the saponin based vaccine (hazard ratio, 2.52; 95% confidence interval, 1.03-6.17) or the commercial vaccine (hazard ratio, 2.61; 95% confidence interval, 1.07-6.38). A significant increase in the risk of T. foetus clearance was found with the combination of saponin plus aluminum hydroxide based vaccine (hazard ratio, 5.12; 95% confidence interval, 2.04-12.83).KEYWORDS: Bovine; Control; Cow; Disease; Immunity; Trichomonas; Venereal","palabras_clave":"Venereal|Disease|Bovine|Cow|Control|Immunity"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15682,"idioma_id":5,"titulo":"Presencia de serotipos de Campylobacter jejuni O:19 en la cadena avícola Argentina","resumen":"Las especies termotolerantes de Campylobacter han tomado gran relevancia en losúltimos a?nos debido a que son los principales agentes zoonóticos causantes de enfermedadestransmitidas por alimentos. Adicionalmente, Campylobacter jejuni serotipo O:19 ha sidorelacionado con el desarrollo del síndrome posdiarreico de Guillain-Barré. El objetivo de estetrabajo fue determinar la proporción de cepas de C. jejuni que se corresponden con el serotipoO:19 dentro de las aisladas en diferentes etapas de 3 cadenas de producción de carne aviar enla provincia de Santa Fe.Se observó que el 18% del total de cepas de C. jejuni recuperadas (10\/55) pertenecían alserotipo O:19; estas se aislaron en 4 de las 5 etapas de producción de carne aviar elegidas a losfines de este estudio. Este hallazgo da cuenta de un riesgo importante para la salud pública delos consumidores y debería ser considerado en los estudios epidemiológicos de Campylobacter,para implementar en forma urgente medidas de control sobre este microorganismo.© 2017 Asociaci´on Argentina de Microbiolog´ýa. Publicado por Elsevier Espa?na, S.L.U. Este es unart´ýculo Open Access bajo la licencia CC BY-NC-ND","palabras_clave":"CAMPYLOBACTER TERMOTOLERANTE|SEROTIPO O:19|GUILLIAN-BARRÉ|POLLOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15696,"idioma_id":4,"titulo":"Stratosphere\/troposphere joint variability in southern South America as estimated from a Principal Components Analysis","resumen":"In order to understand how the tropopause annual evolution relates to the troposphere and lower stratosphere over southern South America, the study analyzes the joint behavior of single and double thermal tropopauses with the 500 and 100 hPa levels in the region. Radiosonde data spanning the period 1973-2014 was used. Geopotential height time series that were filtered known cycles were used as input for an unrotated S-mode Principal Components Analysis. The first three leading modes of variability were analyzed. The first one has a strong semi-annual behavior, linked to wind cycles, with maximum activity in the center of the study region on the lee of the Andes. It appears to be linked to the vertical propagation of planetary and gravity waves. Semi-annual and terannual cycles dominate the second mode, the associated spatial patterns having strong resemblance with the occurrence of cold fronts. The annual time series for the third mode is coupled to a blocking index over the South Atlantic, and the associated spatial structures are also similar to blocking patterns. Results are in good agreement with observations, showing that the use of thermal tropopauses is a valid tool for studying different phenomena taking place in the region.","palabras_clave":"STRATOSPHERE\/TROPOSPHERE JOINT VARIABILITY|SOUTHERN SOUTH AMERICA|PRINCIPAL COMPONENTS ANALYSIS|THERMAL TROPOPAUSE|RADIOSONDES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15719,"idioma_id":5,"titulo":"Los compromisos normativos de la aserción relativista","resumen":"Como han puesto de relieve Evans ('Does tense logic rest upon a mistake?') y García-Carpintero ('Relativism, vagueness, and what is said'), uno de los problemas más importantes respecto de la aserción en el marco de una concepción relativista radical de los discursos evaluativos es dar un tratamiento coherente de los compromisos y de las responsabilidades que la aserción misma genera cuando sus condiciones de corrección son inestables. Construyendo sobre la base de un trabajo de Losada ('Relativismo, corrección y responsabilidad'), el presente trabajo busca ofrecer dicho tratamiento.","palabras_clave":"ASERCIÓN|RELATIVISMO DE LA VERDAD|RELATIVISMO RADICAL|PROBLEMA DE EVANS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15730,"idioma_id":5,"titulo":"Educación a distancia sin distancia","resumen":"Que pasa con la educacion en el contexto actual . posibilidades requerimientos y desafios","palabras_clave":"EDUCACION A DISTANCIA|ERA DIGITAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15743,"idioma_id":4,"titulo":"Intra and interspecific interactions between aphidophagous ladybirds: the role of prey in predator coexistence","resumen":"Cannibalism (CANN) and intraguild predation (IGP) may provide critical energy and nutrients to individuals, and eliminate potential competitors. However, these negative competitive interactions that also may affect the coexistence of predatory species. The spatial and temporal co-occurrence of aphidophagous ladybird species in crops creates opportunities for CANN and IGP, especially when aphids become scarce. The Lotka-Volterra model predicts the coexistence of two species if intraspecific competition is stronger than interspecific interference interactions. Cycloneda sanguinea L. and Eriopis connexa (Germar) (Coleoptera: Coccinellidae) coexist in sweet pepper crops in La Plata (Argentina) consuming mainly Myzus persicae (Hemiptera: Aphidae). The present study used laboratory experiments to estimate levels of CANN and IGP by adults and larvae on eggs, and by adults on larvae, in both the presence and absence of prey in an effort to explain the effect of prey on coexistence of these two predators. Levels of CANN by C. sanguinea and E. connexa were high in absence of aphids, and decreased when prey was present. IGP was bidirectional and asymmetric. Adults and larvae of E. connexa were more voracious intraguild predators of C. sanguinea than vice versa, the former being the stronger intraguild predator and interference competitor. E. connexa always won when larvae of the same instar were paired whereas the larger larvae always won when larvae were of different instars, regardless of species. In the presence of prey, CANN by both species decreased, but IGP by E. connexa on C. sanguinea remained high, suggesting that E. connexa could displace C. sanguinea via interspecific interference competition. Other factors potentially affecting the coexistence of C. sanguinea and E. connexa in sweet pepper crops are discussed.","palabras_clave":"CANNIBALISM|INTRAGUILD PREDATION|APHIDS|COCCINELLIDS|ERIOPIS CONNEXA|CYCLONEDA SANGUINEA|MYZUS PERSICAE."},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15749,"idioma_id":4,"titulo":"Sex chromosomal abnormalities associated with equine infertility:  validation of a simple molecular screening tool in the Purebred  Spanish Horse","resumen":"Chromosomal abnormalities in the sex chromosome pair (ECAX and ECAY) are widely associated with reproductive problems in horses. However, a large proportion of these abnormalities remains undiagnosed due to the lack of an affordable diagnostic tool that allows for avoiding karyotyping tests. Hereby, we developed an STR (single-tandem-repeat)-based molecular method to determine the presence of the main sex chromosomal abnormalities in horses in a fast, cheap and reliable way. The frequency of five ECAX-linked (LEX026, LEX003, TKY38, TKY270 and UCDEQ502) and two ECAY-linked (EcaYH12 and SRY) markers was characterized in 261 Purebred Spanish Horses to determine the efficiency of the methodology developed to be used as a chromosomal diagnostic tool. All the microsatellites analyzed were highly polymorphic, with a sizeable number of alleles (polymorphic information content > 0.5). Based on this variability, the methodology showed 100% sensitivity and 99.82% specificity to detect the most important sex chromosomal abnormalities reported in horses (chimerism, Turner´s syndrome and sex reversal syndromes). The method was also validated with 100% efficiency in 10 individuals previously diagnosed as chromosomally aberrant. This STR screening panel is an efficient and reliable molecular?cytogenetic tool for the early detection of sex chromosomal abnormalities in equines that could be included in breeding programs to save money, effort and time of veterinary practitioners and breeders.","palabras_clave":"chimerism|diagnostic tool|equines|genetic infertility"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15770,"idioma_id":5,"titulo":"Efecto del stress por plomo en Ludwigia peploides e Hydrocotyle ranunculoides","resumen":"Wetlands usually provide a natural mechanism to diminish the transport of toxiccompounds to other compartments of the ecosystem by immobilizing heavy metals and storingthem below ground in roots and\/or soil. The aim of this study is to evaluate the Pb uptake andtranslocation into two aquatic plants - Ludwigia peploides (Kunth) P.H. Ravenand and Hydrocotyleranunculoides L.f. - and to quantify potential histological changes by metal action. For this, an assayin greenhouse was carried out in summer (November to April). Lead, as Pb(NO3)2, was added tothe sediments attaining concentrations of 300 &#956;g Pb\/g sediment (T300) and 900 &#956;g Pb\/g sediment(T900). These treatments were tested against controls without Pb addition and KNO3 addition forquantifying nitrate effect (C300 and C900). The concentration of Pb was determined at root, stem,leaf, water and at different sediment fractions. Histological sections were prepared to determinemorphometric parameters. More than 80% of Pb was associated with little mobile sediment fraction(organic matter-sulfide and oxides of Fe and Mn). Both species, H. ranunculoides and L. peploides,showed a significant increase in root Pb concentration at treatment with Pb addition (p<0.01). Leadconcentration of stem and leaf of H. ranunculoides increased at T300 treatments (p<0.05 and p<0.01,respectively) and T900 (p<0.01) with respect to control treatments. An increase of Pb concentrationin stem and leaf of L. peploides was only observed at T900 (p<0.01). In polluted sediments, innercortex cells of H. ranunculoides root showed less height (p<0.01) and width (p<0.01), and a decreasein porosity (p<0.05) with loss of parenchymatous tissue was observed. The measured parametersof L. peploides were similar to control. Since reducing environments favour Pb immobilization, thedecrease of parenchymatous tissue in H. ranunculoides could contribute to its retention in therhizosphere. The absence of morphological alterations in L. peploides suggests that the studiedphenotype could be tolerant to the assay conditions.Keywords: phytoremediation, aquatic plants, lead, light microscopy, morphological alterations.","palabras_clave":"PHYTOREMEDIATION|AQUATIC PLANTS|LEAD|LIGHT MICROSCOPY|MORPHOLOGICAL ALTERATIONS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15792,"idioma_id":5,"titulo":"MACROFAUNA EDÁFICA ASOCIADA A DIFERENTES AMBIENTES DE UN VIVERO FORESTAL (SANTA FE, ARGENTINA)","resumen":"La edafofauna comprende una gran variedad deorganismos que intervienen en numerosos procesos del suelo, afectando tanto elcrecimiento de la vegetación como el mantenimiento de la productividad. Elobjetivo del trabajo fue estudiar la abundancia y composición de la macrofauna enrelación a tres ambientes con uso del suelo, características edáficas&nbsp; y composición vegetal diferentes, localizadosen el vivero forestal de Recreo Sur (Santa Fe, Argentina). Se extrajeron decada ambiente 15 bloques de suelo en primavera 2013 y otoño 2014siguiendo el método estándar TSBF. Se determinaron densidad, número de familiasy grupos funcionales por ambiente. Se colectaron untotal de 5344 individuos pertenecientes a 17 órdenes y 56 familias. La densidadmedia de la macrofauna mostró diferencias entre ambientes (P&lt; 0,05), destacándose Parquizado con el valor más alto (966ind.m-2). El número de familias fue mayor en Pastizal (43) siguiendoPlantación (31) y Parquizado (29). Los taxa más representativos fueronHymenoptera (47,93%), Haplotaxida (26,83%), Isopoda (8,29%), Coleoptera(7,20%), Chilopoda (3,07%) y Araneae (2,35%). Los grupos funcionales mostrarondiferencias por ambiente (P&lt; 0,05), siendo los más abundanteslos ingenieros del suelo (745 ind.m-2) y los detritívoros (151 ind.m-2)en Parquizado y herbívoros en Pastizal (28 ind.m-2). El grupo depredadores no mostró diferencias entre ambientes (P&gt;0,05). Nuestros resultados muestran que las comunidades de macrofaunavariaron, no sólo en relación al&nbsp; uso delsuelo sino también por la composición vegetal presente en los ambientes delvivero forestal. ","palabras_clave":"MACROINVERTEBRADOS|SUELO|COMPOSICION VEGETAL|USO DEL SUELO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15796,"idioma_id":4,"titulo":"Rational design of dendritic thermoresponsive nanogels that undergo phase transition under endolysosomal conditions","resumen":"In the last few decades, the synthesis of nanodevices has become a very active research field with many applications in biochemistry, biotechnology, and biomedicine. However, there is still a great need for smart nanomaterials that can sense and respond to environmental changes. Temperature- and pH-responsive nanogels (NGs), which are prepared in a one-pot synthesis from N-isopropylacrylamide (NiPAm) and a Newkome-type dendron (ABC) bearing carboxylic acid groups, are being investigated as multi-responsive drug carriers. As a result, NGs have been developed that are able to undergo a reversible volume phase transition triggered by acidic conditions, like the ones found in endolysosomal compartments of cancer cells. The NGs have been thoroughly characterized using dynamic light scattering and spectroscopies, such as infrared, nuclear magnetic resonance, UV-visible, and stimulated Raman. Strong hydrogen bonds have been detected when the ABC moieties are deprotonated, which has led to changes in the transition temperatures of the NGs and a reversible, pH-dependent aggregation. This pH-dependent phase change was exploited for the effective encapsulation and sustained release of the anticancer drug cisplatin and resulted in a faster release of the drug at endolysosomal pH values. The cisplatin-loaded NGs have exhibited high toxicities against A549 cells in vitro, while the unloaded NGs have been found to be not cytotoxic and hemocompatible.","palabras_clave":"SMART NANOGELS|DENDRITIC POLYMERS|PH-THERMO RESPONSIVE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15825,"idioma_id":4,"titulo":"Density of real and complex decomposable univariate polynomials","resumen":"We estimate the density of tubes around the algebraic variety of decomposable univariate polynomials over the real and the complex numbers.","palabras_clave":"Polynomial composition|Real polynomials|Complex polynomials|Volume|Tubes"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15835,"idioma_id":4,"titulo":"Testing assortative mating: evidence from Argentina","resumen":"In this paper we study the marriage market in Argentina. Inparticular, we test the positive -assortative- mating (PAM) hypothesis thatposits that marriages can be positively sorted along the couples education,using survey data from Greater Buenos Aires between 1980 and 2014. First,we use a regression approach to assess assortative mating controlling by manyfamily level characteristics. We nd that the eect of husbands´ educationon wife´s education is positive and signicant. Then, we empirically verifyif the observed matching distribution is super-modular, i.e., the local logodds ratios of education are all positive. We conclude that the data (weakly)supports Becker´s positive assortative mating hypothesis in Argentina. Themodel that best describes marriage formation is more consistent with preference for own type rather than with PAM.","palabras_clave":"MARRIAGE|ASSORTATIVE MATING|EDUCATION|LOG-ODDS RATIOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15877,"idioma_id":4,"titulo":"Multiparameter quantum groups, bosonizations and cocycle deformations","resumen":"The multiparameter quantized enveloping algebras U_q(g)constructed by Hu, Pei and Rosso are presented as the pointed Hopf algebras U(D,l) defined by Andruskiewitsch and Schneider.The result is applied to show that under a certain assumption, U_q(g)depends, up to cocycle deformation, on only one parameter in eachconnected component of the associated Dynkin diagram. In the special case that g is simple, this was already shown by [HPR] inan alternative way.","palabras_clave":"QUANTUM GROUPS|BOSONIZATIONS|COCYCLE DEFORMATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15878,"idioma_id":4,"titulo":"Quantum subgroups of simple twisted quantum groups at roots of one","resumen":"Let G be a connected, simply connected simple complex algebraic group and let e be a primitive lth root of unity with l odd and coprime with 3 if G is of type G_2. We determine all Hopf algebra quotients of the twisted multiparameter quantum functionalgebra O_e^f(G)introduced by Costantini and Varagnolo. This extends the results ofAndruskiewitsch and the first author, where the untwisted case is treated.","palabras_clave":"TWISTED QUANTUM FUNCTION ALGEBRAS|QUANTUM SUBGROUPS|HOPF ALGEBRA QUOTIENTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15910,"idioma_id":5,"titulo":"La electrificación rural en la agenda pública del gobierno de la provincia de Buenos Aires. Argentina, 1946-1955","resumen":"Existe un consenso historiográfico en torno a la contribución de las políticas públicas del peronismo histórico a la ?democratización del bienestar?, en especial en las ciudades (Argentina, 1946-1955). Ahora bien, ¿hasta qué punto la acción redistributiva se encauzó hacia la movilidad social ascendente de los habitantes rurales, en una lógica de equidad social y territorial tendiente a reducir la brecha entre zonas rurales y zonas urbanas? Las evidencias sugieren que, a pesar de que el Estado asumió nuevas funciones en materia social y de que desde distintos ámbitos se admitía la necesidad de mejorar las condiciones de vida de los residentes rurales y desalentar las migraciones internas, la intervención estatal exhibió límites para subyugar las desigualdades en áreas ?extracéntricas?. Eso ocurrió con los servicios públicos, cuya provisión fue problemática en ámbitos menos densamente poblados y más distantes de los grandes centros urbanos. En vista de la importancia que asume la electrificación rural para el mejoramiento de la calidad de vida y para el desarrollo económico, el propósito del trabajo es examinar las concepciones del peronismo histórico sobre la misma y su correlato en el diseño de políticas públicas. Para ello se tendrán en cuenta las iniciativas y los diagnósticos de la época expuestos por técnicos y expertos en la materia. En base a fuentes gubernamentales, prensa y bibliografía publicada en el período estudiado, se prestará particular atención a la provincia de Buenos Aires, evaluando particularidades, cambios y continuidades entre las gobernaciones de Domingo Mercante y Carlos Aloé. La electrificación rural, ¿era concebida como un servicio público indispensable y, como tal, incorporada a la agenda pública? ¿Se la presentaba como respuesta a una demanda social? ¿Qué rol se le asignaba al Estado nacional, provincial y municipal, al sector privado y a las cooperativas? ¿Se priorizaba una lógica de rentabilidad económica u otra de equidad social y territorial para mejorar la calidad de vida del medio rural?","palabras_clave":"PERONISMO|ELECTRIFICACIÓN|BIENESTAR SOCIAL RURAL|PROVINCIA DE BUENOS AIRES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15914,"idioma_id":5,"titulo":"Estado y bienestar rural argentino en la primera mitad del siglo XX. Un problema historiográfico","resumen":"El propósito de este trabajo es avanzar en la construcción del bienestar rural estatal como objeto de interés historiográfico. Con ese propósito, en el siguiente artículo realizamos un análisis crítico del bienestar rural argentino en perspectiva histórica, ciñéndonos a la primera mitad del siglo XX. Para ello, primero, exploramos los avances historiográficos producidos sobre esta temática, sus posibilidades analíticas y algunos vacíos subsistentes. A continuación, debatimos sobre los usos de lo rural en la comprensión histórica de las políticas sociales. Finalmente, resumimos algunos avances realizados en la dilucidación de las experiencias históricas del bienestar rural estatal en la Argentina que pueden ser útiles para una discusión en ciernes.","palabras_clave":"POLÍTICAS PUBLICAS|BIENESTAR RURAL|SIGLO XX|ARGENTINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15915,"idioma_id":5,"titulo":"Introducción al dossier 'Estado y bienestar rural en la Argentina de la primera mitad del siglo XX'","resumen":"El propósito de este dossier ha sido el de problematizar el fenómeno del bienestar durante la primera mitad del siglo XX a través de la singularidad que planteó la experiencia histórica de la población rural en la Argentina. Con ello, nos propusimos descentrar la mirada sobre las políticas sociales en los grandes centros urbanos y aprehender las modalidades de intervención estatal frente a las problemáticas que las poblaciones de menor tamaño, en heterogéneos contextos socioeconómicos e institucionales, plantearon respecto a la distribución del bienestar.","palabras_clave":"ESTADO|BIENESTAR RURAL|ARGENTINA|SIGLO XX"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15929,"idioma_id":5,"titulo":"Sitios web e investigación social. Recetario para cocinar populismo","resumen":"Escribo un breve recetario en donde presentodistintos sitios web que contribuirán a la investigación sobre los populismos latinoamericanosa través de sus directas implicancias para dos canteras importantes en lainvestigación sobre populismo: el análisis del discurso y la fotografía.&nbsp; Bajo la premisa tácita de la necesidad deaprender lenguajes de programación, este texto informa sobre algunasherramientas promovidas desde el campo de las ?humanidades digitales?. &nbsp;","palabras_clave":"HUMANIDADES DIGITALES|POPULISMO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15954,"idioma_id":4,"titulo":"Gram positive bacteria with probiotic potential for the Apis mellifera L. honey bee: the experience in the Northwest of Argentina","resumen":"Apis mellifera L. is one of the most important natural pollinators of significant crops and flowers around the world. It can be affected by different types of illnesses: American foulbrood, Nosemosis, Varroasis, viruses, among others. Such infections mainly cause a reduction in honey production and in extreme situations, the death of the colony. Argentina is the world?s second largest honey exporter and the third largest honey producer, after China and Turkey. Given both the prominence of the honey bee in nature and the economic importance of apiculture in Argentina and the world, it is crucial to develop efficient and sustainable strategies to control honey bee diseases and to improve bee colony health. Gram-positive bacteria, such as lactic acid bacteria, mainly Lactobacillus, and Bacillus spp. are promising options. In the Northwest of Argentina, several Lactobacillus and Bacillus strains from the honey bee gut and honey were isolated by our research group and characterized by using in vitro tests. Two strains were selected because of their potential probiotic properties: Lactobacillus johnsonii CRL1647 and Bacillus subtilis subsp. subtilis Mori2. Under independent trials with both experimental and commercial hives, it was determined that each strain was able to elicit probiotic effects on bee colonies reared in the northwestern region of Argentina. One result was the increase in egg-laying by the queen which therefore produced an increase in bee number and, consequently, a higher honey yield. Moreover, the beneficial bacteria reduced the incidence of two important bee diseases: nosemosis and varroosis. These results are promising and extend the horizon of probiotic bacteria to the insect world, serving beekeepers worldwide as a natural tool that they can administer as is, or combine with other disease-controlling methods.","palabras_clave":"honey bee|probiotic|Lactobacillus|Bacillus"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15961,"idioma_id":4,"titulo":"Self-regeneration of hairy vetch ( Vicia villosa Roth) as affected by seedling density and soil tillage method in a semi-arid agroecosystem","resumen":"Vicia villosa Roth is a forage legume with the capability for biological N fixation and natural reseeding, which could contribute to sustainability in semi-arid regions. This study aimed to determine (i) the relationship between vetch density, seed production and spontaneous seed dispersal; (ii) the impact of the post-dispersal tillage treatment over the soil seedbank dynamics; and (iii) potential predation of the seedbank by feral pigeons. A density range between 50 and 200 plants m&#8722;2 did not influence seed production or seed dispersal. Shallow disc tillage (SDT) clearly favoured self-regeneration, resulting in higher amount of emerged seedlings during autumn compared to no tillage (NT). Based on observed emergence data, the percentage of emerged seedlings under SDT and NT were 38 and 6% of the seedbank, respectively, during 18 months after plot harvest. The lowest emergence values registered under NT could be associated with higher pressure from natural predators, soil-borne pathogens, seed decay by ageing and false breaks. The feral pigeon (Columba livia var.) might be considered the main cause of vetch seedbank depletion in this study. Under controlled conditions, a single pigeon is able to consume, on average, between 184 and 768 seeds per day, depending on seed exposure and alternative food sources availability.","palabras_clave":"HAIRY VETCH|SEED PRODUCTION|FORAGE LEGUME CROP|RESEEDING|PREDATION|ANNUAL PASTURE|ARID-SEMIARID REGION|SEED DORMANCY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":15973,"idioma_id":5,"titulo":"Los sin tierra. Representaciones y estrategias de circulación de reivindicaciones en las sociedades en red","resumen":"El artículo propone un análisis comparativo de las estrategias de divulgación adoptadas por la UST(Argentina) y el MST (Brasil) por medio de sus respectivos espacios Web, frente a los reclamos yreivindicaciones por la propiedad de la tierra de movimientos que surgen y se organizan principalmentepor la defensa de acceso a la tierra. Se indaga la potencialidad de difusión que la sociedad en red ofrece,en especial frente a los reclamos de movimientos que pujan por una Reforma Agraria. El abordaje serealiza desde la perspectiva de las Representaciones Sociales y el Análisis del Discurso y contempla lalógica diferenciada del soporte virtual como espacio de circulación simbólico de la información.","palabras_clave":"TICs|REPRESETACIONES|MOVIMIENTOS SOCIALES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16022,"idioma_id":4,"titulo":"On the three terminal interactive lossy source coding problem","resumen":"In this work we explore the three-node multi-terminal lossy source coding problem which seems to offer a formidable mathematical complexity. We derive an inner bound to the general rate-distortion region of this problem which is a natural extension of the seminal work by Kaspi on the interactive two-terminal source coding problem. It is shown that this (rather involved) inner bound contains several rate-distortion regions of some relevant source coding settings. In this way, besides the non-trivial extension of the interactive two terminal problem, our results can be seen as a generalization and hence unification of several previous works in the field. By specializing the inner bound to particular cases we obtain some novel rate-distortion regions for several lossy source coding problems.","palabras_clave":"SOURCE CODING|DISTORTION|RATE|INTERACTION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16029,"idioma_id":5,"titulo":"La filosofía de la tecnología de André Gorz","resumen":"André Gorz (1923-2007) es más conocido como un pensador de izquierda que colaboró con J. P. Sartre en Les Temps Moderns, que como un filósofo de la tecnología. El objetivo de este trabajo es mostrar que su pensamiento ofrece una reflexión inteligente sobre el papel que puede tener la tecnología en la construcción de una sociedad alternativa a sociedad industrial, es decir, a la estructurada sobre el triple vértice capital, ciencia y técnica. Mi estrategia para delinear el alcance de su filosofía de la tecnología será establecer un contrapunto ?no exhaustivo, pero sí significativo? con la teoría crítica de la tecnología propuesta por el filósofo americano Andrew Feenberg.","palabras_clave":"GORZ|FILOSOFÍA|TECNOLOGÍA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16038,"idioma_id":4,"titulo":"High-technology augmentative communication for adults with post-stroke aphasia: a systematic review","resumen":"Introduction: Augmentative and alternative communication (AAC) systems were introduced into clinical practice by therapists to help compensate for persistent language deficits in people with aphasia. Although, there is currently a push towards an increased focus on compensatory approaches in an attempt to maximize communication function for social interaction, available studies including AAC systems, especially technologically advanced communication tools and systems, known as ?high-technology AAC?, show key issues and obstacles for these tools to become utilized in mainstream clinical practice. Areas covered: The current review synthesizes communication intervention studies that involved the use of high-technology communication devices to enhance linguistic communication skills for adults with post-stroke aphasia. The review focuses on compensatory approaches that emphasized functional communication. It also summarizes recommendations for the report of studies evaluating high-technology devices that may be potentially relevant for other researchers working with adults with post-stroke aphasia. Expert commentary: Taken together with positive results in heterogeneous studies, high-technology devices represent a compensatory strategy to enhance communicative skills in individuals with post-stroke aphasia. Improvements in the design of studies and reporting of results may lead to better interpretation of the already existing scientific results from aphasia management.","palabras_clave":"Aphasia|Review|Communication|High Technology"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16059,"idioma_id":4,"titulo":"THE ROLE OF LEAF CELLULOSE CONTENT IN DETERMINING HOST PLANT PREFERENCES OF THREE DEFOLIATING INSECTS PRESENT IN THE ANDEAN-PATAGONIAN FOREST.","resumen":"Phytophagous insects choose their feeding resources according to their own requirements in addition to properties of the host plants, such as biomechanical defences. The feeding preferences of the native folivorous insects of the Andean-Patagonian forest (Argentina) have rarely been studied. These environments present a wide diversity and abundance of insects associated with trees of the Nothofagus and Lophozonia (Nothofagaceae) genera, which represent the main tree species of the forests of the southern hemisphere. In particular, Lophozonia alpina and Lophozonia obliqua are of great interest because they have a wide distribution, a high capacity for hybridization and exhibit great phenotypic plasticity. This versatility causes substantial variation in the biomechanical properties of leaves, affecting the feeding preferences of insects. The purpose of this work was to study the food selection behaviour of three leaf-chewing insects (Polydrusus nothofagii, Polydrusus roseaus (Coleoptera: Curculionidae) and Perzelia arda (Lepidoptera: Oecophoridae)) associated with L. alpina and L. obliqua as host plants. Based on their choices, our aim was to determine a preference scale for each insect species and the variables on which these preferences were based. Therefore, we selected trees of L. alpina and L. obliqua, measured several properties such as cellulose content and recorded which leaves were eaten. As a result, we determined that the three species of insects feed on both host plants but prefer the leaves of L. obliqua, with cellulose content being the main determining factor for their decisions. However, in the case of P. arda, there was a positive relationship between cellulose and host plant preference, whereas there was an opposite relationship for the weevils. We conclude that during feeding selection, there are some properties of the leaves that have a more important role than others and that the same property does not exert the same behavioural response in all folivorous insects.","palabras_clave":"Bayesian analysis|biomechanical properties|feeding preferences|native forest|phytophagous|Thurstone scale"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16098,"idioma_id":5,"titulo":"La ocupación colonial temprana (s. XVI y XVII) en Casas Quemadas (Cusi Cusi, Rinconada, Jujuy): primeras aproximaciones a las relaciones entre lo global y lo local.","resumen":"En este trabajo presento los resultados de lasexcavaciones realizadas en el Recinto 1 de Casas Quemadas, Cusi Cusi, Jujuy ylos relaciono con el contexto global de la Colonia temprana en la Puna Jujeñadurante los siglos XVI y XVII. Para ello, presento una síntesis de los procesosocurridos en la Puna Jujeña durante el Periodo Tardío o de DesarrollosRegionales (900 -1430 DC), el Periodo Imperial Inka (1430 ? 1536 DC) y elColonial temprano (siglos XVI y XVII); y los relaciono con las distintasocupaciones del Recinto 1. Las diferentes ocupaciones pueden ser interpretadascomo respuestas de los pobladores locales al contexto global de la Conquista.Desde un primer momento, donde el sitio funcionó como un complejo agrícolavinculado con la ocupación Inka de la región, se produce un paulatino abandonoy cambio en la funcionalidad del recinto, que va desde una disminución en lafrecuencia del material recuperado hasta su abandono y reutilización comoparadero en circuitos arrieros vacunos. Este proceso puede vincularse con loscambios producidos por la presencia española y la presión recibida por laspoblaciones locales de insertarse en los circuitos mercantiles capitalistas.","palabras_clave":"PUNA|PASTORES|ARRIERIA|MERCADO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16153,"idioma_id":4,"titulo":"Loss of dystrophin is associated with increased myocardial stiffness in a model of left ventricular hypertrophy","resumen":"Transition from compensated to decompensated left ventricular hypertrophy (LVH) is accompanied by functional and structural changes. Here, the aim was to evaluate dystrophin expression in murine models and human subjects with LVH by transverse aortic constriction (TAC) and aortic stenosis (AS), respectively. We determined whether doxycycline (Doxy) prevented dystrophin expression and myocardial stiffness in mice. Additionally, ventricular function recovery was evaluated in patients 1 year after surgery. Mice were subjected to TAC and monitored for 3 weeks. A second group received Doxy treatment after TAC. Patients with AS were stratified by normal left ventricular end-diastolic wall stress (LVEDWS) and high LVEDWS, and groups were compared. In mice, LVH decreased inotropism and increased myocardial stiffness associated with a dystrophin breakdown and a decreased mitochondrial O2 uptake (MitoMVO2). These alterations were attenuated by Doxy. Patients with high LVEDWS showed similar results to those observed in mice. A correlation between dystrophin and myocardial stiffness was observed in both mice and humans. Systolic function at 1 year post-surgery was only recovered in the normal-LVEDWS group. In summary, mice and humans present diastolic dysfunction associated with dystrophin degradation. The recovery of ventricular function was observed only in patients with normal LVEDWS and without dystrophin degradation. In mice, Doxy improved MitoMVO2. Based on our results it is concluded that the LVH with high LVEDWS is associated to a degradation of dystrophin and increase of myocardial stiffness. At least in a murine model these alterations were attenuated after the administration of a matrix metalloprotease inhibitor.","palabras_clave":"DYSTROPHIN |HYPERTROPHY |DIASTOLIC|MYOCARDIAL STIFFNESS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16154,"idioma_id":4,"titulo":"Macrophytes as dispersal vectors of zooplankton resting stages in a subtropical riverine floodplain","resumen":"The resting stages of freshwater zooplankton constitute a special mechanism for passive dispersal, often displaying a variety of adaptations so as to ease transport. In floodplain systems, macrophytes are one of the most representative biotic groups showing interactions with the zooplankton community. The annual fluctuations in the hydrometric level of the Paraná River favour the displacement of this aquatic vegetation in floodplain environments. This paper hypothesizes that the roots and submerged portions of different macrophytes contain zooplankton resting stages which are able to hatch when environmental conditions are favourable. In turn, this contributes to the dispersal of zooplankton by plants when they are displaced by the flood pulse. Six macrophyte species were sampled (Eichhornia crassipes, Azolla filiculoides, Limnobium spongia, Pistia stratiotes, Eichhornia azurea and Nymphoides indica) from lakes within the Parana´ River floodplain. Roots and submerged portions of vegetation were stored (90 days) at 4 °C then incubated at 25 °C for 90 days. Hatchling emergence was recorded at 2-day intervals during this period. In total, 70 zooplankton taxa were recorded in all macrophyte samples; rotifers were the most representative group (69%) followed by cladocerans (28%) and copepods (3%). The roots and submerged parts of aquatic vegetation house viable zooplankton resting stages. This phenomenon allows the dispersal of resting stages and therefore colonization of new habitats during the displacement of macrophyte species.","palabras_clave":"FLOOD PULSE|CONNECIVITY|DIVERSITY|EGG BANKS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16155,"idioma_id":4,"titulo":"Disruption of the hatching dynamics of zooplankton egg banks due to glyphosate application","resumen":"Hatching rhythms of eggs banks are important processes because they favor species co-existence and promote resilience of ecosystems after natural disturbances. Anthropogenic stressors can disrupt such natural hatching dynamics. This work examines the effects of concentrations ranging from 1 to 8 mg l-1 of a commercial glyphosate-based formulation (Sulfosato TouchdownR) on the hatching dynamics of zooplankton dormant stages, present in the sediment of a natural lake. Sediment samples were collected from the surface sediment (<10 cm deep) of an isolated shallow lake free from pesticide pollution. An ex situ emergence assessment method was carried out and four treatments plus one control (without pesticide) were performed with three replicate each. Zooplankton hatching from the resting stages was monitored during 30 days. In total, 30 zooplankton taxa were recognized. The species diversity decreased significantly at concentration above 2.7 mg l-1 glyphosate. The proportion of cladocerans within hatchling organisms decreased, while that of rotifers Bdelloidea increased in all treatments with glyphosate. Time of the first hatching (TFH), time of maximum hatching (TMH) and the frequency of hatchings (FH) of most zooplankton species were also altered. In conclusion, the application of a glyphosate-based pesticide selectively affected the hatching dynamic of zooplankton egg banks, which suggest that these resting structures are highlysensitive to the toxicity of the pesticide.","palabras_clave":"PESTICIDES|BDELLOIDEA |RESTING EGGS|RESILIENCE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16178,"idioma_id":4,"titulo":"MIToS.jl: mutual information tools for protein sequence analysis in the Julia language","resumen":"Motivation: MIToS is an environment for mutual information analysis and a framework for protein multiple sequence alignments (MSAs) and protein structures (PDB) management in Julia language. It integrates sequence and structural information through SIFTS, making Pfam MSAs analysis straightforward. MIToS streamlines the implementation of any measure calculated from residue contingency tables and its optimization and testing in terms of protein contact prediction. As an example, we implemented and tested a BLOSUM62-based pseudo-count strategy in mutual information analysis.","palabras_clave":"Julia Language|mutual information|sequence analysis|structure analysis"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16186,"idioma_id":4,"titulo":"Three new Idiops (Mygalomorphae: Idiopidae) from Argentina and redescription of the male of I. hirsutipedis Mello-Leit&atilde;o, 1941","resumen":"Three new Argentinean species of the front-eyed trapdoor spider genus Idiops namely I. minguito sp. nov. from Salta and Jujuy provinces, I. piluso sp. nov. from Córdoba province and I. tolengo sp. nov. from Santiago del Estero province, are described. The male of I. hirsutipedis is redescribed and new distributional data in Argentina are presented for this species and for I. clarus. An identification key for all these species is provided.","palabras_clave":"MYGALOMORPHAE|NEW SPECIES |TRAPDOOR SPIDERS|ARGENTINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16235,"idioma_id":5,"titulo":"Evolución y escenarios futuros de la deforestación en el suroeste de la provincia del Chaco, Argentina","resumen":"En este estudio se analizó el proceso de deforestación en el suroeste de la provincia del Chaco, desde 1989 hasta 2010 y su proyección al año 2030. Para ello se utilizaron imágenes Landsat 5 TM, procesadas en estudios previos mediante clasificación supervisada con el software ENVI, para obtener los cambios de coberturas de suelo en el período 1989-2010. A través del Sistema de Información Geográfica IDRISI se aplicaron métodos de reclasificación y superposición temática (Overlay), asimismo se realizaron simulaciones espaciales con cadenas de Markov y autómata celular. Los resultados permiten afirmar que en el periodo 1989-2010, el área de bosques se redujo en un valor superior al 70%. La simulación de cambios para los años 2020 y 2030 indica que, de continuar la tendencia actual, la pérdida de superficie forestal podría alcanzar el 74,64% y el 76,28%, respectivamente.","palabras_clave":"Deforestación|Teledetección |Sistemas de Información Geográfica"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16271,"idioma_id":4,"titulo":"The predator and prey behaviors of crabs: from ecology to neural adaptations","resumen":"Predator avoidance and prey capture are among the most vital of animal behaviors. They require fast reactions controlled by comparatively straightforward neural circuits often containing giant neurons, which facilitates their study with electrophysiological techniques. Naturally occurring avoidance behaviors, in particular, can be easily and reliably evoked in the laboratory, enabling their neurophysiological investigation. Studies in the laboratory alone, however, can lead to a biased interpretation of an animal´s behavior in its natural environment. In this Review, we describe current knowledge ? acquired through both laboratory and field studies ? on the visually guided escape behavior of the crab Neohelice granulata. Analyses of the behavioral responses to visual stimuli in the laboratory have revealed the main characteristics of the crab´s performance, such as the continuous regulation of the speed and direction of the escape run, or the enduring changes in the strength of escape induced by learning and memory. This work, in combination with neuroanatomical and electrophysiological studies, has allowed the identification of various giant neurons, the activity of which reflects most essential aspects of the crabs´ avoidance performance. In addition, behavioral analyses performed in the natural environment reveal a more complex picture: crabs make use of much more information than is usually available in laboratory studies. Moreover, field studies have led to the discovery of a robust visually guided chasing behavior in Neohelice. Here, we describe similarities and differences in the results obtained between the field and the laboratory, discuss the sources of any differences and highlight the importance of combining the two approaches.","palabras_clave":"ESCAPE RESPONSE|LOBULA|CRUSTACEANS|FIELD EXPERIMENTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16280,"idioma_id":4,"titulo":"Calculation of debonding strength at the interface of particles with different shapes and matrix","resumen":"The debonding process at the interface of filler-matrix is studied. The relevanceof this process lays in its triggering effect of toughening mechanisms in polymer basedcomposites. Based on a micromechanical model, a general approach of the debondingcondition was derived. The proposed expression was applied for different particleshapes: spherical, ellipsoid, cubic, rectangular and fiber. Results of debonding strengthversus geometric parameters of the different particles showed that oblate ellipsoids andcubic particles can be easily analyzed as spherical filler.","palabras_clave":"Polymer-matrix composites (PMCs)|Debonding|Interface\/interphase|Analytical modelling"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16292,"idioma_id":5,"titulo":"Una lectura sobre las prácticas de lectura de los textos de enseñanza Secundaria de Lengua y Literatura: apuntes preliminares de un Proyecto de Investigación","resumen":"El texto compartirá los problemas, hipótesis, objetivos y avances del P. I. ?Tram(p)as textuales: una lectura sobre las prácticas de lectura de los textos de enseñanza Secundaria de Lengua y Literatura? que llevamos adelante desde el año 2013 un grupo de profesores y alumnos de la UNPSJB.  Este proyecto se propone describir, sistematizar y analizar las prácticas de lectura o modos de leer de los textos educativos de la Educación Secundaria pertenecientes al área de Lengua y Literatura; en función de determinar los modelos de lectura que están siendo canonizados desde las políticas educativas estatales; y, por ende, la concepción de literatura que circula en estas instituciones educativas. El análisis se enfocará en determinar qué posturas epistemológicas subyacen en estos modelos de lectura, cuál es el canon crítico que explícita o implícitamente diseña al objeto de estudio denominado literatura y qué implicancias y relaciones tienen estas prácticas con los proyectos culturales y políticos hegemónicos. El proyecto se centra en analizar los alcances de estos modelos de lectura, los conceptos y categorías que circulan en ellos, las afiliaciones que estos explicitan, detentan o esconden y, por ende, la definición de campo y frontera disciplinar en las prácticas de lectura legitimadas desde los textos de Lengua y Literatura de enseñanza secundaria.","palabras_clave":"Enseñanza|Lengua|Literatura|Practicas de lectura"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16301,"idioma_id":4,"titulo":"Mechanism, Explanatory Pluralism and Efficient Coding Explanation in Neuroscience","resumen":"There is a growing debate within the Philosophy community concerning the unity and diversity of explanation in neuroscience. The new Mechanist philosophy claims that neuroscience exhibits a mosaic unity in which models from multiple scientific fields contribute to the collective mechanistic explanation of an explanandum phenomenon &#966; by setting causal constraints on the space of possible mechanisms for &#966;. Non-mechanist philosophers acknowledge the relevance (even the centrality) of mechanistic research, but they want to emphasize the plurality and diversity of explanatory research programs in neuroscience. In this paper I argue, first, that the kind of explanatory pluralism many non-mechanist philosophers endorse which I call 'causally restricted pluralism' is not a genuine alternative to Mechanism. Then, I present a liberalized interpretation of explanatory pluralism, one according to which there are models in neuroscience that contribute to the collective explanation of some phenomenon &#966; but that are not intended to set causal constraints on the space of possible mechanisms for &#966;. Finally, I review an explanatory research program in neuroscience, namely, efficient coding explanation, that is better accounted for by the liberalized interpretation of pluralism.","palabras_clave":"Mechanism|Unity of Science|Explanatory Pluralism|Efficient Coding Explanation"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16313,"idioma_id":5,"titulo":"Posibles herramientas jurídicas para la erradicación de la corrupción en el servicio de agua en Argentina","resumen":"LATINDEX CATÁLOGO (cumple requisitos 20 y 21) - DOSSIER: LOS DESAFÍOS DE LA POLÍTICA PÚBLICA Y GESTIÓN DEL AGUA Y SANEAMIENTO EN ARGENTINA. El objetivo principal de este trabajo es el de realizar un estudio de casos de privatización y re-estatización del servicio de suministro del agua potable en las provincias de Buenos Aires y Santa Fe (1993-2006), a la luz del sistema de indicadores de calidad ambiental ?Presión, Estado y Respuesta?. La medición de la corrupción se realiza a través de la adaptación jurídica del sistema de indicadores de Golden y Picci. Desde el punto de vista metodológico, se utilizará el método de observación documental, el analítico y el comparativo de datos. Una posible conclusión tras los incumplimientos legales que surgieron al aplicar el sistema de indicadores de Golden y Picci, es que la normativa vinculada con el servicio de agua no es lo suficientemente rigurosa como para desalentar dichas prácticas y defender los derechos de los usuarios del servicio.","palabras_clave":"SERVICIO|AGUA|ARGENTINA|CORRUPCIÓN|INDICADORES|AMBIENTALES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16317,"idioma_id":4,"titulo":"Four approaches to guide ecological restoration in Latin America","resumen":"WILLEY Library, puesto 33 en ranking en SPI (Schorlarly Publisers Indicators) de 2014 - There is strong upswing in conservation and restoration efforts in Latin America (LA), particularly in the recent decades after several countries have committed to international agreements such as the Aichi targets of the Convention on Biological Diversity, Initiative 20×20, and the Bonn Challenge. To fulfill these agreements, the practice of ecological restoration has to be defined based on ecological knowledge, but also on the specific social, economic, and legal aspects of each country in the region. Here, we give some examples about the national understanding of ecological restoration in 10 countries of LA. We identify difficulties and opportunities to define restoration priorities and needs, and discuss some approaches to cope with economic constraints and agreements, including the potential role of restoration networks in this process. On the basis of the socioecological complexity of these countries and the expectations they have in relation to restoration, we proposed four approaches to guide restoration practice and policy in the region: (1) including biodiversity and ecosystem services approach into ecosystem restoration initiatives; (2) promoting restoration in their frequently human modified landscapes; (3) accounting for cost?benefit trade-offs; and (4) assembling ?horizontal? communication frameworks. These approaches should be based at national levels, but adapted to local-regional levels, in a bottom-up perspective. We consider that national and international restoration networks in the region can help to overcome difficulties, fostering a solid scientific community, helping to develop national approaches that better match the specific conditions of each country and enhancing communication among different groups of stakeholders.","palabras_clave":"BIODIVERSITY|ECOSYSTEM |SERVICES|PUBLIC|POLICY|SOCIO|ECOLOGICAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16340,"idioma_id":5,"titulo":"Los países productores de materias primas en la unidad mundial de la acumulación de capital: un enfoque alternativo","resumen":"El objetivo de este artículo es presentar los fundamentos de un enfoque alternativo, difundido recientemente en la literatura especializada, sobre la naturaleza de las economías nacionales históricamente dedicadas a la producción de materias primas para el mercado mundial. A tal fin, se discute la relevancia que tiene para la comprensión de este tipo de economías, en primer lugar, el reconocimiento del capital como una relación social de contenido mundial y de forma nacional y, en segundo lugar, la dilucidación de cómo se realiza la ?ley del valor? en el mercado mundial cuando se intercambian mercancías portadoras de renta de la tierra. Finalmente, se considera la especificidad que, dadas estas determinaciones fundamentales, caracteriza a los países productores de materias primas tomando como base investigaciones recientes sobre al caso argentino. En el curso de esta presentación se destacan las diferencias sustantivas que tiene este enfoque con las explicaciones dominantes en la literatura especializada.","palabras_clave":"MERCADO MUNDIAL|LEY DEL VALOR INTERNACIONAL|SUBDESARROLLO|ECONOMÍAS LATINOAMERICANAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16353,"idioma_id":4,"titulo":"A look inside an emerging nuclear supplier of the South. Advocacy coalitions and change in Argentine foreign nuclear policy","resumen":"What light can Foreign Policy Analysis (FPA) shed on how and when the balance of power between domestic coalitions in foreign nuclear policymaking changes and how these different balances directly affect policy outcomes? Drawing on interviews with scientists, technologists and career diplomats, this comprehensive examination of Argentine nuclear exports policy as public policy aims to depict when and how policies varied between 1976 and 2004, due to shifts in the balance amongst advocacy coalitions, albeit of incentives and constraints placed by international and institutional nuclear environments. The article provides a better account of how Argentine nuclear foreign policy changed under the influence of four competitive and contrasting advocacy coalitions: the pro-import substitution and protectionist coalition, the pro-technological autonomy and South-South trade coalition, the pro-business and commercial openness coalition and the antinuclear and pro-environment coalition.","palabras_clave":"Foreign Policy Analysis|Foreign Nuclear Policy|Advocacy Coalitions|Science Diplomacy"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16354,"idioma_id":4,"titulo":"Analysis of the interaction between neotectonic and surface processes in a low-land intracratonic setting of South America","resumen":"The Quaternary sedimentary record in the continental interiors has generally been studied taking into consideration the climatic forcing. However episodes of uplift controlling the development of landforms have often been dismissed. The interiors of continents are typically considered to have low deformation rates, lower than the rates of exogenous processes. Deformation in the middle of the Pampean plains, an intracratonic setting of South America, has been observed to have generated an elevated area surrounded by lowland plains. This elevated area is susceptible to fluvial erosion. From this fact we developed a geomorphologic modelling constrained from geomorphic markers in order to estimate the relative incidence of the different factors that control erosion in lowland landscapes. An adapted erosion code was employed, which combines fluvial incision (the stream power law), an uplift function spatially distributed and the hillslope diffusion equation. A low-DEM was achieved for restoring an initial non-deformed topography affected by low fluvial incision. It represents a palaeosurface chrono-stratigraphically constrained. The estimation of the model parameters was achieved by applying the inversion method. The best-fit between the numerical solution (calculated topography) and the measured topography (simulated by means a DEM) was approached by comparison of the stream longitudinal profiles. The yield numerical approach suggests that a geomorphological modelling based on the stream power law is possible to be applied in low-land landscapes. For this, a large scale change of the magnitude of the processes modelling the landscape should be expected in comparison with mountain erosional environments. Remarkably low K empirical values (K= 5.10-6) suggest that the extremely low slopes exert a larger influence on the stream power in low-land landscapes. Regional uplift rates can be higher (0.35 mm\/yr) than it is generally expected in low uplift rate settings (0.1 - 0.25 mm\/yr). These estimations evidence highly dynamic surface and tectonic processes controlling the landscape evolution over intermediate time scales in an intracratonic setting.","palabras_clave":"Tectonic Geomorphology|Intracratonic settings |Late Pleistocene\/Holocene fluvial incision rates| low uplift rate regions"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16374,"idioma_id":4,"titulo":"Effect of pH at drainage on the physicochemical, textural and microstructural characteristics of mozzarella cheese from goat milk","resumen":"The aim of this study was a contribution to standardazation the process of making mozzarella cheese from goat milk by draining at different pH values 5.0 (MC50), 5.3 (MC53) and 5.6 (MC56), so as to obtain a product with suitable physicochemical, microstructural and textural characteristics. MC50 had lower protein and calcium, with very few strands. MC53 had adequate moisture content, fat, protein and calcium. The cheese yield was higher, the hardness parameters were lower, and the microstructure revealed the presence of long, thin strands, giving it the distinctive texture for this type of cheese. MC56 curd did not reach a good stretching property, requiring longer exposure to heating to obtain the yarn. This resulted in lower retention of fat, lower cheese yield, increased calcium and hardness values, and absence of strands. Overall, the goat milk presented aptitude for processing this type of cheese, however the pH 5.3 was selected to obtain a product with suitable physicochemical, textural and microstructural characteristics.","palabras_clave":"GOAT MILK|MOZZARELLA|CHEESE|pH|MICROSTRUCTURE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16376,"idioma_id":4,"titulo":"Global Stability Results for Swit- ched Systems Based on Weak Lyapunov Functions","resumen":"In this paper we study the stability of nonlinear and time-varying switched systems under restricted switching. We approach the problem by decomposing the system dynamics into a nominal-like part and a perturbation-like one. Most stability results for perturbed systems are based on the use of strong Lyapunov functions, i.e. functions of time and state whose total time derivative along the nominal system trajectories is bounded by a negative definite function of the state. However, switched systems under restricted switching may not admit strong Lyapunov functions, even when asymptotic stability is uniform over the set of switching signals considered. The main contribution of the current paper consists in providing stability results that are based on the stability of the nominal-like part of the system and require only a weak Lyapunov function. These results may have wider applicability than results based on strong Lyapunov functions. The results provided follow two lines. First, we give very general global uniform asymptotic stability results under reasonable boundedness conditions on the functions that define the dynamics of the nominal-like and the perturbation-like parts of the system. Second, we provide inputto- state stability (ISS) results for the case when the nominal-like part is switched linear-time-varying. We provide two types of ISS results: standard ISS that involves the essential supremum norm of the input and a modified ISS that involves a power-type norm.","palabras_clave":"SWITCHES|LYAPUNOV METHODS|SWITCHED SYSTEMS|ASYMPTOTIC STABILITY|NONLINEAR SYSTEMS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16390,"idioma_id":4,"titulo":"Natural vibrations and buckling of a spatial lattice structure using a continuous model derived from an energy approach","resumen":"Lattice structures composed by parallel members named chords (or legs for vertical configurations) and connected by diagonals are very common among steel constructions in Civil and Mechanical Engineering and in particular, in the telecommunications industry. In the present study, a continuous model of a typical spatial lattice structure is derived. The legs configure a triangular cross-section and the diagonals are arranged in a zig-zag pattern. The differential system is derived from the potential and kinematic energies of the discrete model as the sums of each component contribution. Then, after accepting that the number of diagonals is large enough, the sums are approximated in the limit with classical integrals. Thus, the discrete system is replaced with a continuous formulation. The natural vibration problem of a lattice mast with a zig-zag diagonal pattern is studied using the proposed model. Also, the axial load influence is also accounted for through the second-order effect allowing to solve the buckling problem. Static deflection problems are also addressed. The Hamilton principle application yields the governing differential system in terms of nine unknown displacements. Several examples are solved numerically and the results are compared with the outcomes of a finite element spatial model. It is shown that there is an excellent agreement. The proposed continuous model can represent adequately the spatial lattice with a strong reduction in the degrees of freedom and the time of computation of the solution in comparison with a finite element approach.","palabras_clave":"SPATIAL LATTICE|ENERGY|FREQUENCIES|STATIC DEFLECTION|BUCKLING"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16422,"idioma_id":5,"titulo":"RANGO GEOGRÁFICO Y ESTRUCTURA ESPACIAL DE LINAJES GENÉTICOS EN SOPHORA LINEARIFOLIA (FABACEAE), UN ARBUSTO ENDÉMICO DE LAS SIERRAS CENTRALES DE ARGENTINA","resumen":"Las sierras de Córdoba y San Luis albergan una gran riqueza de especies endémicas. Un grupo importante de ellas muestra una distribución disyunta entre ambas serranías. Hasta la actualidad no existían estudios genéticos que permitieran inferir procesos históricos asociados a este patrón. Con este propósito caracterizamos el área de distribución y el patrón filogeográfico de Sophora linearifolia, abarcando todo su rango geográfico que incluye Sierras Chicas (SC) y Cumbres de Gaspar (CG) en Córdoba y suroeste de las Sierras de San Luis (SL). Contrastamos la distribución actual con la distribución predicha a partir del modelado del nicho ecológico. Analizamos el nivel de variabilidad, la estructuración espacial del marcador de ADN cloroplastidial trnH-psbA y reconstruimos las relaciones genealógicas entre los haplotipos. Las distribuciones actual y predicha mostraron una disyunción entre Córdoba y San Luis, pero la distribución actual presentó una disyunción entre SC y CG que no fue modelada en la distribución potencial. Se obtuvieron 8 haplotipos de distribución restringida con bajos niveles de diferenciación genética agrupados en 4 filogrupos: SC, CG y dos en SL. Nuestros resultados indican que S. linearifolia presentaría baja capacidad de dispersión y que se habría diversificado recientemente, sugiriendo que se trataría de un neoendemismo.","palabras_clave":"ADN CLOROPLASTIDIAL|BIOGEOGRAFIA|DISTRIBUCION DISYUNTA|FILOGEOGRAFIA|MODELADO DE NICHO ECOLOGICO|NEOENDEMISMOS|SIERRAS PAMPEANAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16429,"idioma_id":5,"titulo":"El recurso a los animales en la obra de Cromacio de Aquileya","resumen":"La literatura patrística recurrió muy frecuentemente a la construcción de analogías entre ciertos animales y determinados individuos, grupos religiosos, tipos humanos o entidades. El fenómeno, sin embargo, ha permanecido prácticamente al margen de los intereses de los investigadores al  menos por  cuanto concierne  a la  obra  de los  obispos del  norte de  la Península Itálica de finales del siglo IV y comienzos del V. El presente trabajo se propone presentar algunas reflexiones sobre la cuestión derivadas del análisis de los Sermones y del Tractatus   in   Mathaeum  de   Cromacio   de   Aquileya   (?392-406?).   Tras   una   primera aproximación  cuantitativa,   nos   detendremos   en   la   consideración   de   los   objetivos perseguidos por el uso de tales analogías y en la observación de algunos de sus mecanismos de construcción y de legitimación.","palabras_clave":"CROMACIO DE AQUILEYA|LITERATURA PATRÍSTICA|ANIMALES|ANALOGÍAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16467,"idioma_id":4,"titulo":"Extinction and recovery of an avoidance memory impaired by scopolamine","resumen":"Pre-training administration of scopolamine (SCP) resembles situations of cholinergic dysfunction, leading to memory impairment of mice trained in an inhibitory avoidance task. We suggest here that SCP does not impair memory formation, but acquisition is affected in a way that reduces the strength of the stored memory, thus making this memory less able to control behavior when tested. Hence, a memory trace is stored, but is poorly expressed during the test. Although weakly expressed, this memory shows extinction during successive tests, and can be strengthened by using a reminder. Our results indicate that memories stored under cholinergic dysfunction conditions seem absent or lost, but are in fact present and experience common memory processes, such as extinction, and could be even recovered by using appropriate protocols.","palabras_clave":"MEMORY EXPRESSION|AMNESIA|MEMORY EXTINCTION|MEMORY RECOVERY|SCOPOLAMINE|CHOLINERGIC DYSFUNCTION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16469,"idioma_id":5,"titulo":"AVANCES EN EL ESTUDIO DE BIODETERIORO ASOCIADO A PRESENCIA DE LÍQUENES EN MATERIALES ARQUEOLOGICOS LÍTICOS. LA PRIMAVERA (SANTA CRUZ, ARGENTINA)","resumen":"RESUMENCon el objetivo de indagar acerca del biodeterioro causado por líquenes creciendo sobre materiales arqueológicos líticos, en este trabajo preliminar se analizaron diferentes artefactos procedentes de la localidad La Primavera. La metodología de análisis incluye técnicas de observación de bajos y altos aumentos y análisis de EDAX. Se identifican los líquenes presentes y se observan las superficies de estos artefactos que constituyen soportes para su crecimiento. Se observó y analizó la diversidad de especies presentes y se reconocieron cuatro tipos de bioalteraciones asociadas (microperforaciones, desagregación superficial de la roca, microfracturaciones internas y microfracturaciones superficiales). Entre los morfotipos identificados, el que al parecer causa mayores daños es el crustoso endolítico, seguido del folioso. Estas bioalteraciones dificultan la observación de los caracteres tecnológicos principales, así como estudios específicos acerca de la funcionalidad del instrumental lítico  lo que produce pérdida de información. Conocer más detalladamente cómo estas bioalteraciones afectan a estos materiales es relevante para las interpretaciones arqueológicas. Por lo tanto, este trabajo es una importante contribución al estudio de biodeterioro sobre artefactos líticos que hasta el momento no ha sido objeto de investigaciones específicas.","palabras_clave":"BIODETERIORO|LÍQUENES|ARTEFACTOS LITICOS ARQUEOLÓGICOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16519,"idioma_id":5,"titulo":"Valoración económica de los efectos de la contaminación por vertido de residuos sólidos urbanos. El caso del aglomerado urbano del Gran Mendoza, Argentina","resumen":"En América Latina, la mayoría de los sitios de disposición final de los residuos sólidos urbanos carece de la infraestructura necesaria para controlar adecuadamente la contaminación que produce la basura enterrada. En este trabajo se estima, en términos monetarios, el cambio en el bienestar social por los posibles efectos que estos sitios imponen al medio ambiente. Se aplicó el método de los experimentos de elección discreta para estimar el valor que tiene para los ciudadanos del Gran Mendoza (Argentina) los efectos del vertido sobre la calidad del agua, calidad del aire y la proliferación de vectores. Se estimó  que una disminución de la calidad del agua, efecto del vertido que más preocupa a la población, equivale en términos de pérdida de bienestar por hogar a un gasto promedio anual de 182,49 pesos argentinos (20,48 dólares estadounidenses) a precios de 2015. Esta información puede ser de interés para los administradores de la gestión integral de RSU, gestores del territorio y ecologistas en el diseño de sus programas y actividades.","palabras_clave":"RESIDUOS SÓLIDOS URBANOS|MÉTODO DE LOS EXPERIMENTOS DE ELECCIÓN DISCRETA |BIENESTAR SOCIAL|GRAN MENDOZA|CALIDAD DEL AGUA|CALIDAD DEL AIRE|PROLIFERACIÓN DE VECTORES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16539,"idioma_id":4,"titulo":"Methylene blue oxidation over iron oxide supported on activatedcarbon derived from peanut hulls","resumen":"In order to contribute to the environment preservation, catalysts based on iron oxides supported onactivated carbon were prepared from peanut hulls and evaluated in Fenton reaction to remove methy-lene blue from model wastewaters. The activated carbons were prepared by simultaneous carbonizationand activation of peanut hulls with low amounts of sodium hydroxide and then impregnated with ironnitrate solutions to get samples with 5, 7.5,10, 12.5 and 15 wt.% Fe. All solids were microporous andmade of hematite and magnetite supported on activated carbon. The amount of magnetite changed withiron content and was related to surface oxidation, producing more oxygenated groups (carboxylic acids,lactones, carboxylic anhydrides and phenols) than activated carbon. Both activated carbons and iron-based catalysts were able to remove methylene blue from aqueous streams by adsorption and oxidation,the activity of activated carbon being assigned to oxygenated groups. For iron oxide-based catalysts, theadsorption capacity was related to the increase of surface oxygenated groups while the oxidation activitywas assigned to the amount and crystals size of magnetite, besides the surface oxygenated groups. Theassociation of these properties led to catalysts with close performances, being the catalyst with 10 wt.%Fe slightly more efficient than the others in dye removal. The obtained catalysts produced low amountsof byproducts, being promising to remove dyes in industrial wastewaters. In addition, they have theadvantage of being prepared with less sodium hydroxide than the traditional preparations, decreasingthe amount of wash water, besides reducing the amounts of peanut hulls disposed in the environment.","palabras_clave":"Activated carbonPeanut hulls|Iron oxide|DyesMethylene blue|Fenton reaction"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16545,"idioma_id":4,"titulo":"Adaptive metabolic rewiring to chronic SFK inhibition","resumen":"Src family kinases (SFK) are key regulators of cellular proliferation, differentiation, survival, motility and angiogenesis. As such, SFK inhibitors are being tested in clinical trials to prevent metastasis as an alternative to current treatment regimens for a variety of cancers including breast cancer. To contribute to the development of molecular tools improving SFK-targeted therapies, we used the SFK inhibitor dasatinib and a well characterized triple negative breast cancer cell line (BT20). Comparison of the response of BT20 cells with acquired resistance to dasatinib and its? parental counterpart suggest that chronic exposure to SFK inhibition results in increased dependency on TGF&#946; signaling for proliferation, both in the absence or the presence of dasatinib. In addition, we found that acquired (but not de novo) resistance to dasatinib was reduced by non-cytotoxic concentrations compounds hindering on PI3K, mTORC1 signaling, endoplasmic reticulum stress or autophagy.","palabras_clave":"acquired resistance|SKF inhibition|PI3K|TGF&#946;|metabolism"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16554,"idioma_id":4,"titulo":"The process of lipid storage in insect oocytes: the involvement of &#946;-chain of ATP synthase in lipophorin-mediated lipid transfer in the Chagas´ disease vector Panstrongylus megistus (Hemiptera: Reduviidae). Article","resumen":"Lipophorin is the main lipoprotein in the hemolymph of insects. During vitellogenesis, lipophorin delivers its hydrophobic cargo to developing oocytes by its binding to non-endocytic receptors at the plasma membrane of the cells. In some species however, lipophorin may also be internalized to some extent, thus maximizing the storage of lipid resources in growing oocytes. The ectopic Beta chain of ATP synthase (Beta-ATPase) was recently described as a putative non-endocytic lipophorin receptor in the anterior midgut of the hematophagous insect Panstrongylus megistus. In the present work, females of this species at the vitellogenic stage of the reproductive cycle were employed to investigate the role of Beta-ATPase in the transfer of lipids to the ovarian tissue. Subcellular fractionation and western blot revealed the presence of Beta-ATPase in the microsomal membranes of the ovarian tissue, suggesting its localization in the plasma membrane. Immunofluorescence assays showed partial co-localization of Beta-ATPase and lipophorin in the membrane of oocytes as well as in the basal domain of the follicular epithelial cells. Ligand blotting and co-immunoprecipitation approaches confirmed the interaction between lipophorin and Beta-ATPase. In vivo experiments with an anti-Beta-ATPase antibody injected to block such an interaction demonstrated that the antibody significantly impaired the transfer of fatty acids from lipophorin to the oocyte. However, the endocytic pathway of lipophorin was not affected. On the other hand, partial inhibition of ATP synthase activity did not modify the transfer of lipids from lipophorin to oocytes. When the assays were performed at 4°C to diminish endocytosis, the results showed that the antibody interfered with lipophorin binding to the oocyte plasma membrane as well as with the transfer of fatty acids from the lipoprotein to the oocyte. The findings strongly support that Beta-ATPase plays a role as a docking lipophorin receptor at the ovary of P. megistus, similarly to its function in the midgut of such a vector. In addition, the role of Beta-ATPase as a docking receptor seems to be independent of the enzymatic ATP synthase activity.","palabras_clave":"LIPID METABOLISM|LIPOPHORIN|OOCYTE |TRIATOMINE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16619,"idioma_id":5,"titulo":"El Qualitative Comparative Analysis (QCA) como herramienta analítica. Dos aplicaciones para el análisis de entrevistas","resumen":"El objetivo del artículo es presentar una técnica que aborda de manera consistente y sistemática la etapa analítica de datos cualitativos: el llamado Qualitative Comparative Analysis (QCA) o Análisis Comparativo Cualitativo. En la primera parte se presentan los conceptos básicos vinculados a las herramientas lógicas (álgebra booleana) que son el fundamento del QCA. En la segunda, se ejemplifica la aplicación del QCA a partir de la información producida en dos investigaciones: un estudio sobre los trabajadores de la cosecha de algodón en Chaco y una investigación sobre las empresas vitivinícolas en la provincia de Mendoza.","palabras_clave":"QUALITATIVE COMPARATIVE ANALYSIS|ANALISIS ENTREVISTAS|DATOS CUALITATIVOS|METODOLOGIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16635,"idioma_id":4,"titulo":"Pharmacokinetics of the antimicrobial drug sulfanilamide is altered in a preclinical model of  vascular calcification","resumen":"In vascular smooth muscle, calcium overload is linked to advancing age. The pharmacokinetics of Sulfanilamide (SA), a compound with antibacterial properties, was evaluated in a preclinical model of vascular calcification. SA was used since it is useful to study possible modifications in the renal and hepatic management of drugs. Vascular calcification was induced by administration of a single high dose of vitamin D3 to rats (treated group) 10 days before the experiments. A parallel control group was processed.The decrease of renal blood flow due to calcification of the renal arteries explains, at least in part, the decrease in the renal clearance of SA observed in treated rats. The liver metabolic function increased in treated rats as demonstrated by increases in plasma appearance rate of acetylated-Sulfanilamide(ASA), hepatic ASA content and hepatic N-acetyltransferase activity. The decrease in renal excretion of SA was not completely compensated by the hepatic metabolism increase, since the elimination rate of SA from the central compartment (K1-0) decreased in the treated group. In summary, in this experimental model with sustained arterial calcinosis induced by a single high dose of vitamin D3 10 days before the experiments, the pharmacokineticsof an aminobenzenesulfonamide is modified, at least in part, by theincrease in the activity of hepatic N-acetyltransferase and the decrease in renal blood flow. This study emphasizes the importance of considering the presence of vascular calcification when a drug dose scheme is performed, in order to optimize pharmacotherapeutic results.","palabras_clave":"SULFANILAMIDE|VASCULAR CALCIFICATION|RAT|PHARMACOKINETICS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16639,"idioma_id":4,"titulo":"Intra- and Extracellular Biosynthesis and Characterization of Iron Nanoparticles from Prokaryotic Microorganisms with Anticoagulant Activity","resumen":"Background: The use of microorganisms for the synthesis of nanoparticles (NPs) is relatively new in basic research and technology areas. Purpose: This work was conducted to optimized the biosynthesis of iron NPs intra- and extracellular by Escherichia coli or Pseudomonas aeruginosa and to evaluate their anticoagulant activity. Study Design\/Methods: The structures and properties of the iron NPs were investigated by Ultraviolet?visible (UV-vis) spectroscopy, Zeta potential, Dynamic light scattering (DLS), Field emission scanning electron microscope (FESEM)\/ Energy dispersive X-ray (EDX) and transmission electron microscopy (TEM). Anticoagulant activity was determined by conducting trials of Thrombin Time (TT), Activated Partial Prothrombin Time (APTT) and Prothrombin Time (PT). Results: UV-vis spectrum of the aqueous medium containing iron NPs showed a peak at 275 nm. The forming of iron NPs was confirmed by FESEM\/ EDX, and TEM. The morphology was spherical shapes mostly with low polydispersity and the average particle diameter was 23 ± 1 nm. Iron NPs showed anticoagulant activity by the activation of extrinsic pathway. Conclusion: The eco-friendly process of biosynthesis of iron NPs employing prokaryotic microorganisms presents a good anticoagulant activity. This could be explored as promising candidates for a variety of biomedical and pharmaceutical applications.","palabras_clave":"ANTICOAGULANT ACTIVITY|ESCHERICHIA COLI|PSEUDOMONAS AERUGINOSA|MICROBIAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16648,"idioma_id":4,"titulo":"A study on fibre addition to gluten free bread: its effects on bread quality and in vitro digestibility","resumen":"The aim of this study was to assess the impact of fibre addition on gluten-free (GF) dough properties and bread technological quality, and on protein and starch in vitro digestibility. Soluble (Inulin, In) and insoluble fibres (oat fibre, OF, and type IV resistant starch, RSIV) were used at 5 and 10% substitution levels. Dough firmness increased when insoluble fibres were added, and decreased when In was used. Incorporation of insoluble fibres resulted into bread with a low specific volume (SBV) since firmer dough were more difficult to expand during proofing and baking. Staling rate was reduced after fibre addition, with the exception being OF 10%, as its lower SBV may have favoured molecule re-association. In general, protein and starch digestibility increased when fibres were added at 5%, and then decreased after further increasing the level. Fibres may have disrupted bread crumb structure, thus increasing digestibility, although the higher addition may have led to a physical and\/or chemical impediment to digestion. Inulin has well-known physiological effects, while RS presented the most important effect on in vitro starch digestibility (GI). These results showed the possibility of adding different fibres to GF bread to decrease the GI and increase protein digestibility, while obtaining an overall high quality end-product.","palabras_clave":"Gluten free bread|Soluble and insoluble fibres|Bread technological quality|Protein in vitro digestibility"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16693,"idioma_id":4,"titulo":"Adsorption thermodynamics of two-domain antifreeze proteins: theory and Monte Carlo simulations","resumen":"In the present work, the adsorption of three-domain antifreeze proteins on ice is studied by combininga statistical thermodynamics based-theory and Monte Carlo simulations. The three-domainprotein is modeled by a trimer, and the ice surface is represented by a lattice of adsorption sites.The statistical theory, obtained from the exact partition function of non-interacting trimers adsorbedin one dimension and its extension to two dimensions, includes the configuration of themolecule in the adsorbed state, and allows the existence of multiple adsorption states for the protein.We called this theory ?lattice-gas model of molecules with multiple adsorption states' (LGMMAS).The main thermodynamics functions (partial and total adsorption isotherms, Helmholtz freeenergy and configurational entropy) are obtained by solving a non-linear system of j equations,where j is the total number of possible adsorption states of the protein. The theoretical results arecontrasted with Monte Carlo simulations, and a modified Langmuir model (MLM) where the arrangementof the adsorption sites in space is immaterial. The formalism introduced here providesexact results in one-dimensional lattices, and offers a very accurate description in two dimensions(2D). In addition, the scheme is capable to predict the proportion between coverage degrees correspondingto different conformations in the same energetic state. In contrast, the MLM doesnot distinguish between different adsorption states, and shows severe discrepancies with the 2Dsimulation results. This finding indicates that adsorbate structure and l attice geometry play fundamentalroles in determining the statistics of multistate adsorbed molecules, and consequently,must be included in the theory.","palabras_clave":"Protein|Adsorption|Antifreeze|theory"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16721,"idioma_id":4,"titulo":"Morphometric analysis of camelid remains from the Alero Deodoro Roca (ADR) site (Córdoba, Argentina). An attempt to characterize body size variability in Sierras Pampeanas Australes region.","resumen":"This paper focuses in the morphometric analyses of Lama guanicoe remains recovered from the hunter-gatherer archaeological site Alero Deodoro Roca (ADR), located at Sierras Pampeanas region (Córdoba Argentina), an area that has little information on the body-size variability of these artiodactyls. Because of the sparse osteometric data in the region, we focused on determining inter-intraspecific differentiation of wild camelids through corroborated osteometric techniques and multivariate statistical analyses of proximal phalanges. Our results showed a clear interspeci&#64257;c differentiation between modern vicuñas and archaeological specimens. We could also distinguish at least 3 guanaco size groups (small, medium and large) with the archaeological remains from the late Holocene (3000-3600 BP) of the site, presenting medium size characteristics. Finally this paper aims at establishing a first approach in the characterization of guanaco body size in the mountainous region of Córdoba, known as Sierras Pampeanas.","palabras_clave":"Lama guanicoe|osteometrics|multivariate analyses|Hunter-gatherer's"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16751,"idioma_id":4,"titulo":"Multibiomarker responses in aquatic insect Belostoma elegans (Hemiptera) to organic pollution in freshwater system","resumen":"The present study analyzes a battery of biomarkers in the water bug Belostoma elegans from a stream polluted with organic matter (OMS), and another one considered as reference site (RS) during spring-summer season (December to March). Biochemical parameters of glucidic, lipidic and oxidative metabolic pathways were analyzed in males and females of insects. In general, no significant differences were observed in all biomarkers assayed between both sexes, except lactate concentration which was higher in males than females (p<0.0006) in the first three months. About carbohydrate metabolism parameters, only pyruvate-kinase showed significant differences between insects collected in both streams (p<0.05) during December. However, the total lipid content, saturated fatty acid, and mainly, triacylglycerol were higher in insects from RS compared to those from OMS (p<0.002) in all months sampled. Levels of lipoperoxidation, protein oxidation, reduced glutathione and glutathione-S-transferase activity showed no differences between insects collected from both streams. Nevertheless, the significant increase observed in superoxide dismutase and catalase activities (p<0.004) could be due to the elevated oxidative metabolism in insects from RS compared to those from OMS with lower dissolved oxygen. Regarding those responding biomarkers, males accounted better the differences between the two sites during the study period. In conclusion, our results support that lipidic energetic reserves and antioxidant enzyme activities in B. elegans could be used as biomarkers of environmental pollution by organic matter.","palabras_clave":"AQUATIC INSECTS|BIOCHEMICAL COMPOSITION|BIOMARKERS|ECOTOXICOLOGY|ORGANIC MATTER|WASTEWATER BIOLOGICAL EFFECTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16756,"idioma_id":4,"titulo":"Strain engineering and process optimization for enhancing the production of a thermostable steryl glucosidase in Escherichia coli","resumen":"Biodiesels produced from transesterification of vegetable oils have a major problem in quality due to the presence of precipitates, which are mostly composed of steryl glucosides (SGs). We have recently described an enzymatic method for the efficient removal of SGs from biodiesel, based on the activity of a thermostable &#946;-glycosidase from Thermococcus litoralis. In the present work, we describe the development of an Escherichia coli-based expression system and a high cell density fermentation process. Strain and process engineering include the assessment of different promoters to drive the expression of a codon-optimized gene, the co-expression of molecular chaperones and the development of a high cell density fermentation process. A 200-fold increase in the production titers was achieved, which directly impacts on the costs of the industrial process for treating biodiesel.","palabras_clave":"Steryl glucosidase |Green chemistry|Biodiesel|Molecular chaperones"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16774,"idioma_id":5,"titulo":"El 'modelo' norteamericano en la reglamentación de las intervenciones federales en la Argentina del siglo XIX. Debates en el Congreso de la Nación (1869 y 1894)","resumen":"Este trabajo examina el lugar de la legislación de los Estados Unidos como referencia doctrinal en los dos mayores debates legislativos de la Argentina decimonónica acerca de la reglamentación de las facultades del gobierno nacional para intervenir en las provincias.","palabras_clave":"Argentina|Estados Unidos|Intervenciones Federales|Congreso Nacional"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16798,"idioma_id":4,"titulo":"Bifidobacterium infantis NLS Super Strain Reduces the Expression of &#945;-Defensin-5, a Marker of Innate Immunity, in the Mucosa of Active Celiac Disease Patients.","resumen":"BACKGROUND:We have previously shown a reduction of gastrointestinal symptoms after the oral administration of Bifidobacterium infantis Natren Life Start super strain (NLS-SS) in untreated celiac disease (CD) patients. The symptomatic improvement was not associated with changes in intestinal permeability or serum levels of cytokines, chemokines, or growth factors. Therefore, we hypothesized that the beneficial symptomatic effect observed previously in patients with CD treated with B. infantis may be related to the modulation of innate immunity.GOALS:To investigate the potential mechanisms of a probiotic B. infantis Natren Life Start super strain on the mucosal expression of innate immune markers in adult patients with active untreated CD compared with those treated with B. infantis×6 weeks and after 1 year of gluten-free diet (GFD).METHODS:Numbers of macrophages and Paneth cells and &#945;-defensin-5 expression were assessed by immunohistochemistry in duodenal biopsies.RESULTS:We showed that GFD decreases duodenal macrophage counts in CD patients more effectively than B. infantis. In contrast, B. infantis decreases Paneth cell counts and expression of &#945;-defensin-5 in CD (P<0.001).CONCLUSIONS:The results identify differential innate immune effects of treatment with B. infantis compared with 1 year of GFD. Further studies are needed to investigate synergistic effects of GFD and B. infantis supplementation in CD.","palabras_clave":"Bifidobacterium infantis|Celiac Disease"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16801,"idioma_id":4,"titulo":"Physicochemical and environmental characterization of pistachio shells","resumen":"Numerous residual biomasses have been studied in a variety of uses, including biomass-energy processes, as adsorbentof heavy metals contained in liquid effluents, as source of chemicals with higher added value, as raw materials inconstruction industry, etc. In this work, a very common and abundant residual biomass, which is found in the area of fruitproduction in Argentina, peach stones, is studied. This material has been characterized in relation to its possible use as poreformer in ceramic matrices, with the following techniques: scanning electron microscopy with semi quantitative chemicalanalysis (SEM-EDS), differential thermal and thermogravimetric analysis (DTA-TGA), X ray diffraction (XRD), loss weighton ignition (LOI), among others. Figure 1 shows the microscopic appearance of the stones by SEM. A fibrous structure on theouter surface and granular on the inside are observed. The semi-quantitative chemical analysis by EDS shows, in addition tolarge quantities of C and O, the presence of elements such as Na, K, Mg, Al, Si and Fe. DTA-TGA results show some exothermicpeaks corresponding to the combustion of hemicellulose, cellulose and lignin phases. From these curves, it is possible toestimate the composition of this material in relation to the content of adsorbed gases and water, biopolymers and inorganicfraction (ash formation). As the structure of the biopolymers (hemicellulose, cellulose and lignin) becomes more complex, thecombustion temperatures are higher. The DTA-TGA analysis shows that this organic material is burned in a wide temperaturerange, between 300°C and 550°C. This is important to ensure that when this material is incorporated into clay mixtures as poreformer, the sintering process takes place without crack formation in the brick. This test further indicates that after the heattreatment, the residual material that will eventually be incorporated into the bricks (ashes) is less than 2%. XRD analysis revealsthe presence of some peaks corresponding to semi crystalline cellulose.","palabras_clave":"Ceramics|Biomass|Pistachio"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16827,"idioma_id":4,"titulo":"Numerical simulations of windblown dust over complex terrain: The Fiambalá Basin episode in June 2015","resumen":"On 13 June 2015, the London Volcanic Ash Advi- sory Centre (VAAC) warned the Buenos Aires VAAC about a possible volcanic eruption from the Nevados Ojos del Salado volcano (6879 m), located in the Andes mountain range on the border between Chile and Argentina. A vol- canic ash cloud was detected by the SEVIRI instrument on board the Meteosat Second Generation (MSG) satellites from 14:00UTC on 13 June.In this paper, we provide the first comprehensive descrip-tion of this event through observations and numerical sim- ulations. Our results support the hypothesis that the phe- nomenon was caused by wind remobilization of ancient py- roclastic deposits (ca. 4.5 ka Cerro Blanco eruption) from the Bolsón de Fiambalá (Fiambalá Basin) in northwestern Ar- gentina.We have investigated the spatiotemporal distribution of aerosols and the emission process over complex terrain to gain insight into the key role played by the orography and the condition that triggered the long-range transport episode. Numerical simulations of windblown dust were performedusing the ARW(Advanced Research WRF) core of the WRF (Weather Research and Forecasting) model (WRF-ARW) and FALL3D modeling system with meteorological fields downscaled to a spatial resolution of 2km in order to re- solve the complex orography of the area. Results indicate that favorable conditions to generate dust uplifting occurred in northern Fiambalá Basin, where orographic effects caused strong surface winds. According to short-range numerical simulations, dust particles were confined to near-ground lay- ers around the emission areas. In contrast, dust aerosols were injected up to 5?6km high in central and southern regions of the Fiambalá Basin, where intense ascending airflows are driven by horizontal convergence. Long-range transport numerical simulations were also per-formed to model the dust cloud spreading over northern Ar- gentina. Results of simulated vertical particle column mass were compared with the MSG-SEVIRI retrieval product.We tested two numerical schemes: with the default configura- tion of the FALL3D model, we found difficulties to simulate transport through orographic barriers, whereas an alternative configuration, using a numerical scheme to more accurately compute the horizontal advection in abrupt terrains, substan- tially improved the model performance.","palabras_clave":"NUMERICAL SIMULATIONS|RESUSPENSION EVENT|FIAMBALA BASIN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16853,"idioma_id":4,"titulo":"Obese neuronal PPAR&#947; KO mice are leptin sensitive but show impaired glucose tolerance and fertility","resumen":"PPAR&#947; is expressed in the hypothalamus in areas involved in energy homeostasis and glucose metabolism. In this study, we created a deletion of PPAR&#947; (BKO) in mature neurons in female mice to investigate its involvement in metabolism and reproduction. We observed that there was no difference in age at puberty onset between female BKOs and littermate controls, but the BKOs gave smaller litters when mated and fewer oocytes when ovulated. The female BKO mice had regular cycles but showed an increase in the number of cycles with prolonged estrus. The mice also had increased LH levels during the LH surge and histological examination showed hemorrhagic corpora lutea. The mice were challenged with a 60% high fat diet. Metabolically the female BKO mice showed normal body weight, glucose and insulin tolerance, and leptin levels but were protected from obesity-induced leptin resistance. The neuronal knockout also prevented the reduction in estrous cycles due to the HFD. Examination of ovarian histology showed a decrease in the number of primary and secondary follicles in both genotypes due to the HFD, but the BKO ovaries showed an increase in the number of hemorrhagic follicles. In summary, our results show that neuronal PPAR&#947; is required for optimal female fertility, but is also involved in the adverse effects of diet-induced obesity by creating leptin resistance potentially through induction of the repressor Socs3. - See more at: http:\/\/press.endocrine.org\/doi\/abs\/10.1210\/en.2016-1818#sthash.yRrX8XJ0.dpuf","palabras_clave":"Leptin|Obesity|PPARg|Reproduction"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16865,"idioma_id":4,"titulo":"Ferrioxalate-assisted solar photo-Fenton degradation of a herbicide at pH conditions close to neutrality","resumen":"The solar photo-Fenton degradation of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) in aqueous solution at a natural pH (pH = 5) using ferrioxalate as iron source was investigated. The kinetic model proposed and validated in a previous contribution was used to predict the reactants concentrations during the oxidation process in a non-concentrating pilot-plant solar reactor. The effects of hydrogen peroxide to 2,4-D initial concentration ratios (R), temperature, and radiation levels were studied. Furthermore, the spectral UV\/visible and broadband solar radiation fluxes incident on the reactor window were evaluated by the Simple Model for the Atmospheric Radiative Transfer of Sunshine (SMARTS2) code. The complete destruction of 2,4-D and its main intermediate 2,4-dichlorophenol (2,4-DCP) was achieved in all the experimental runs in only 90 and 120&nbsp;min of reaction, respectively. In agreement with these results, a reduction of toxicity in the system (expressed as % of inhibition of Vibrio fischeri) for longer times to 90&nbsp;min of reaction was attained. It is important to emphasize the good agreement between kinetic model results and experimental data obtained.","palabras_clave":"2,4-D |FERRIOXALATE|NEUTRAL PH|SOLAR PHOTO-FENTON"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16875,"idioma_id":4,"titulo":"Search for photons with energies above 10 18 eV using the hybrid detector of the Pierre Auger Observatory","resumen":"A search for ultra-high energy photons with energies above 1 EeV is performed using nine years of data collected by the Pierre Auger Observatory in hybrid operation mode. An unprecedented separation power between photon and hadron primaries is achieved by combining measurements of the longitudinal air-shower development with the particle content at ground measured by the fluorescence and surface detectors, respectively. Only three photon candidates at energies 1 - 2 EeV are found, which is compatible with the expected hadroninduced background. Upper limits on the integral flux of ultra-high energy photons of 0.027, 0.009, 0.008, 0.008 and 0.007 km-2 sr-1 yr-1 are derived at 95% C.L. for energy thresholds of 1, 2, 3, 5 and 10 EeV. These limits bound the fractions of photons in the all-particle integral flux below 0.1%, 0.15%, 0.33%, 0.85% and 2.7%. For the first time the photon fraction at EeV energies is constrained at the sub-percent level. The improved limits are below the flux of diffuse photons predicted by some astrophysical scenarios for cosmogenic photon production. The new results rule-out the early top-down models - in which ultra-high energy cosmic rays are produced by, e.g., the decay of super-massive particles - and challenge the most recent super-heavy dark matter models.","palabras_clave":"Photons|Pierre Auger Observatory"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16900,"idioma_id":4,"titulo":"Evaluation of the proper coherence representation in random flow generation based methods","resumen":"The interest in synthetic methods relies in the fact that reliability of methodologies such as large eddy simulations (LES) or direct numerical simulations strongly depends on how well the developed turbulence is characterized, which generally leads to computationally expensive simulations. Turbulence generation methods allow the initialization and up-keeping of the velocity fluctuations field to promote the observed\/needed turbulence in the flow. In this work the methodology known as ?modified discretizing and synthesizing random flow generation? (MDSRFG) jointly with a LES method is analyzed for its use in the study of tall building aerodynamics. A comparison with other generation techniques, that are closely related by their features and their conceptual origins, is presented with particular emphasis on the correct representation of the coherence of the velocity field. Particularly, an expression for the coherency function for the MDSRFG is derived. After an analysis and revision of these generation methodologies, the turbulent air flow around a rectangular prismatic model is computationally simulated. A comparison of the results obtained from different methods is performed. The resulting wind loads on the model, along with the statistical characteristics of the flow, show that the MDSRFG technique allows to represent a field of spatially correlated velocities correctly.","palabras_clave":"Turbulence synthesis|Computational Fluid Dynamics|Large eddy simulation|OpenFOAM|Tall buildings"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16914,"idioma_id":4,"titulo":"Effect of cement composition on the early hydration of blended cements with natural zeolite","resumen":"This paper studies the addition (0?40% w\/w) of natural zeolite (NZ, 84% clinoptilolite) in blended cements made with Portland cement (PC) with low and medium C3A content. The isothermal calorimetry was used to understand the effect of NZ on the early cement hydration. For low C3A cement, the addition of NZ produces mainly a dilution effect and then the heat released curve is similar to plain cement with lower intensity. For medium C3A cement, the curve shows the C3S peak in advance and a high intensity of third peak attributed to C3A hydration. The high cation fixed of NZ reduces the ions concentration (especially alkalis) in the mixing water stimulating the PC hydration. The flowability decreases when the NZ replacement level increases. Results of Fratini?s test show that NZ with both PCs used presents slow pozzolanic activity. At early age, XRD and FTIR analyses confirm that hydration products are the same as that of the corresponding PC and the CH is progressively reduced after 28 days and some AFm phases (hemi- and monocarboaluminate) appear depending on the NZ percentage and the PC used. For low replacement levels, the compressive strength is higher than the corresponding PC from 2 to 28 days. For high replacement levels, the early compressive strength is lower than that of corresponding plain PC and the pozzolanic reaction improves the later compressive strength of blended cements.","palabras_clave":"Zeolite|Hydration \u0002 Cement |Isothermal calorimetry \u0002 |Cation exchange"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16915,"idioma_id":4,"titulo":"Study of dimensional change of high-silicon ductile iron with ADI and Dual-Phase-ADI microstructures starting from different as-cast structures","resumen":"In this work the percent dimensional change (DC%) and its dispersion in high silicon Ductile Iron with ADI and Dual-Phase-ADI structures obtained through heat treatment starting from different as-cast microstructures, was studied. Specimens were obtained from three different melts with Si content ranging from 3.1 to 4.2%. Dual-Phase-ADI structures were obtained using special heat treatment, starting from as-cast structures. Regarding dimensional change,DC% in ADI and Dual-Phase-ADI decrease as Si% and the proportion of ferrite phase in as-cast specimens increased. On the other hand, DC% increased with austenitizing temperature and ausferrite content in the final microstructure. A fuzzy model to predict DC% in ADI parts was adapted to include DC% prediction in Dual-Phase-ADI. The fuzzy model allowed to predict the DC% for ADI and Dual-Phase-ADI parts with an root mean square <0.05%.","palabras_clave":"Dimensional Change|Dual-Phase-ADI|High Silicon Ductile Iron|Fuzzy modeling"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16968,"idioma_id":5,"titulo":"UN APORTE A LA EDUCACIÓN COMO PRÁCTICA DE LIBERTAD. LA CÁTEDRA GESTIÓN Y DESARROLLO DE LA VIVIENDA POPULAR?,","resumen":"La intención de esta ponencia es presentar una propuesta formativa, precursora, innovadora y motivadora para la creación de otras cátedras en distintas universidades de nuestro país y de Latinoamérica, a treinta años de su creación. Intentaremos recuperar brevemente el camino recorrido a través de algunos ejemplos de prácticas de enseñanza-aprendizaje, llevados adelante durante losúltimos años, en las dimensiones docencia, extensión e investigación.También presentaremos una nueva propuesta curricular como continuidad del camino iniciado. Este complejo académico pretende consolidar una modalidad de acción que articule la teoría con la práctica concreta, cogestionando con otras disciplinas, otros actores sociales y, fundamentalmente, con los destinatarios.","palabras_clave":"EDUCACION |HABITAT SOCIAL|PROBLEMÁTICA HABITACIONAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16979,"idioma_id":4,"titulo":"The bead on a rotating hoop revisited: an unexpected resonance","resumen":"The bead on a rotating hoop is a typical problem in mechanics, frequently posed to junior science and engineering students in basic physics courses. Although this system has a rich dynamics, it is usually not analysed beyond the point particle approximation in undergraduate textbooks, nor empirically investigated. Advanced textbooks show the existence of bifurcations owing to the system´s nonlinear nature, and some papers demonstrate, from a theoretical standpoint, its points of contact with phase transition phenomena. However, scarce experimental research has been conducted to better understand its behaviour. We show in this paper that a minor modification to the problem leads to appealing consequences that can be studied both theoretically and empirically with the basic conceptual tools and experimental skills available to junior students. In particular, we go beyond the point particle approximation by treating the bead as a rigid spherical body, and explore the effect of a slightly non-vertical hoop´s rotation axis that gives rise to a resonant behaviour not considered in previous works. This study can be accomplished by means of digital video and open source software. The experience can motivate an engaging laboratory project by integrating standard curriculum topics, data analysis and experimental exploration","palabras_clave":"NUMERICAL METHODS|LAGRANGIAN MECHANICS|EXPERIMENTS|RIDIG BODIES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16990,"idioma_id":4,"titulo":"Micropillar Resonators for Optomechanics in the Extremely High 20?100-GHz Frequency Range","resumen":"Strong confinement, in all dimensions, and high mechanical frequencies are highly desirable forquantum optomechanical applications. We show that GaAs\/AlAs micropillar cavities fully confine notonly photons but also extremely high frequency (19?95 GHz) acoustic phonons. A strong increase of theoptomechanical coupling upon reducing the pillar size is observed, together with record room-temperatureQ-frequency products of 10 14 . These mechanical resonators can integrate quantum emitters or polaritoncondensates, opening exciting perspectives at the interface with nonlinear and quantum optics.","palabras_clave":"OPTOMECHANICS|MICROPILLAR|CAVITY|DBR"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16991,"idioma_id":4,"titulo":"The production and utilization of GDP-glucose in the biosynthesis of trehalose-6-phosphate by Streptomyces venezuelae","resumen":"*Equally contributed to the workTrehalose-6-phosphate synthase OtsA from streptomycetes is unusual in that it uses GDP-glucose as the donor substrate rather                     than the more commonly used UDP-glucose. We now confirm that OtsA from Streptomyces venezuelae has such a preference for GDP-glucose and can utilise ADP-glucose to some extent too. A crystal structure of the enzyme shows                     that it shares twin Rossmann-like domains with the UDP-glucose-specific OtsA from Escherichia coli. However, it is structurally more similar to Streptomyces hygroscopicus VldE, a GDP-valienol-dependent pseudo-glycosyltransferase enzyme.","palabras_clave":"trehalose-6P|actinobacteria|glucosyltransferase|GDP-glucose"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":16992,"idioma_id":4,"titulo":"PT-VWD -posing diagnostic and therapeutic challenges- small case series","resumen":"Despite the increased worldwide awareness, over the last decade, of the platelet type von Willebrand Disease (PT-VWD), many uncertainties remain around this rare platelet bleeding disorder. This report aims to correctly identify and study the phenotype of new patients and highlights the diagnostic and therapeutic challenges this disease remains to pose. We describe four PT-VWD cases confirmed by genetic analysis in which either the diagnosis and\/or the treatment posed challenge. We provide the details of the clinical presentation, laboratory analysis and the treatment and the responses in each case. We show that in addition totype 2B VWD, PT-VWD can be misdiagnosed as idiopathic thrombocytopenicpurpura (ITP), neonatal alloimmune thrombocytopenia (NAIT) and unexplained gestational thrombocytopenia. The disease can be diagnosed as early as 1 year of age and with phenotypically normal parents. Bleeding in some patients can be managed successfully using Humate P and DDAVP combined with tranexamic acid with no significant thrombocytopenia. We provide for the first time an evidence of an efficient response to rFVIIa in PT-VWD. Anaphylactic reaction to VWF preparations may be related to PT-VWD and the development of HLA antibodies is not uncommon. Progressive thrombocytopenia with normal VWF levels can be seen with PT-VWD and the platelet count was normalized at 2.5 weeks postpartum in one case. We conclude these studies represent a record of clinical observations\/interventions that help improve diagnoses\/management of PT-VWD, highlight the variations in age and clinical presentations, laboratory diagnostic approaches, the importance of genetic testing for accurate diagnosis and consideration of therapeutic alternatives.","palabras_clave":"PT-VWD|genotype|phenotype|VWD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":17006,"idioma_id":4,"titulo":"The metamorphic basement of the southern Sierra de Aconquija, Eastern Sierras Pampeanas: Provenance and tectonic setting of a Neoproterozoic back- arc basin","resumen":"The Eastern Sierras Pampeanas are mainly composed of Neoproterozoic?early Palaeozoic metamorphic complexes whose protoliths were sedimentary sequences deposited along the western margin of Gondwana. South of the Sierra de Aconquija, Eastern Sierras Pampeanas, a voluminous metamorphic complex crops out. It is mainly composed of schists, gneisses, marbles, calk-silicate schists, thin layers of amphibolites intercalated with the marbles and granitic veins. The new data correlate the Sierra de Aconquija with others metamorphic units that crop out to the south, at the middle portion of the Sierra de Ancasti. Bulk rock composition reflects originally shales, iron rich shales, wackes, minor litharenites and impure limestones as its protoliths. Moreover, comparisons with the northern Sierra de Aconquija and from La Majada (Sierra de Ancasti) show similar composition. Amphibolites have a basaltic precursor, like those from the La Majada (Sierra de Ancasti) ones. The analyzed metamorphic sequence reflects low to moderate weathering conditions in the sediments source environment and their chemical composition would be mainly controlled by the tectonic setting of the sedimentary basin rather than by the secondary sorting and reworking of older deposits. The sediments composition reveal relatively low maturity, nevertheless the Fe ? shale and the litharenite show a tendency of minor maturity among them. The source is related to an acid one for the litharenite protolith and a more basic to intermediate for the other rocks, suggesting a main derivation from intermediate to felsic orogen. The source of the Fe- shales may be related to and admixture of the sediments with basic components. Overall the composition point to an upper continental crust as the dominant sediment source for most of the metasedimentary rocks. The protolith of the amphibolites have basic precursors, related to an evolving back- arc basin. The chemical data in combination with the specific sediment association (wackes, shales, Fe- shales and minor litharenites) are characteristic for turbidity currents deposits along tectonically active region. They are also commonly associated with calcareous clays (marbles), commonly observed in the evolution of basins with slope and shelf derived carbonate turbidites. The amphibolites members are probably derived from lava-flows synchronous with the sedimentation during the basin evolution. The basin was controlled by a continental island arc possible evolving to a back-arc setting, as indicated for the mixed nature of the inferred source. The metasedimentary sequence from the Cuesta de La Chilca have petrographic, structural and strong chemical similarities, building a north-south striking belt from the north of the Sierra de Aconquija and to the south along the Sierra de Ancasti (La Majada area). The observed similarities allow to present this portion of the Eastern Sierras Pampeanas as a crustal block that records the sedimentary sequences developed along the geodynamic context of the southwestern margin of Gondwana during the Neoproterozoic and Early Palaeozoic.","palabras_clave":"METASEDIMENTARY|GEOCHEMISTRY|TECTONIC SETTING|EASTERN PAMPEAN RANGES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":17007,"idioma_id":4,"titulo":"Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization.","resumen":"While PKC-mediated phosphorylation of protein kinase D1 (PKD1) has been extensively characterized, little is known about PKD1 regulation by other upstream kinases. Here, we report that stimulation of epithelial or fibroblastic cells with G protein-coupled receptor (GPCR) agonists, including angiotensin II or bombesin induced rapid and persistent PKD1 phosphorylation at Ser203, a highly conserved residue located within the PKD1 N-terminal domain. Exposure to PKD or PKC family inhibitors did not prevent PKD1 phosphorylation at Ser203, indicating that it is not mediated by autophosphorylation. In contrast, several lines of evidence indicated that the phosphorylation of PKD1 at Ser203 is mediated by kinases of the class I PAK subfamily. Specifically: 1) exposing cells to four structurally unrelated PAK inhibitors (PF-3758309, FRAX486, FRAX597 and IPA-3) that act via different mechanisms abrogated PKD1 phosphorylation at Ser203; 2) siRNA-mediated knockdown of PAK1 and PAK2 in IEC-18 and Swiss 3T3 cells blunted PKD1 phosphorylation at Ser203; 3) Phosphorylation of Ser203 was markedly increased in vitro when recombinant PKD1 was incubated with either PAK1 or PAK2 in the presence of ATP. PAK inhibitors did not interfere with GPCR activation-induced rapid translocation of PKD1 to the plasma membrane but strikingly prevented the dissociation of PKD1 from the plasma membrane and blunted the phosphorylation of nuclear targets, including class IIa histone deacetylases (HDACs).","palabras_clave":"GPCR|PKD|PAK|CANCER"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":17013,"idioma_id":5,"titulo":"La Sierra de Santiago y el Valle de Catamarca (Gobernación del Tucumán) a principios del siglo XVII: reflexionando sobre una nueva regionalización","resumen":"Presentamos el análisis de un informe fechado enfebrero de 1607, resultado de la Visita al Partido de laSierra ?dependiente y parte de la jurisdicción de laciudad de Santiago del Estero?, que fue realizada porel Teniente de Naturales Francisco de Betanzos quien,por orden del Gobernador del Tucumán Alonso deRibera, recorrió la tierra aplicando las Ordenanzas deAbreu y desagraviando a los indios. La visita incluyeinformación sobre el valle de Catamarca y la laderaoriental del cordón Ancasti y Alto-Gracián, lassociedades indígenas y el funcionamiento de lasencomiendas. Su análisis nos permite proponer unanueva regionalización para la Gobernación delTucumán y una posible complementariedadeconómica entre sus distintos espacios aprovechadapor los encomenderos en el período temprano colonial.","palabras_clave":"COLONIA TEMPRANA|SANTIAGO DEL ESTERO|VALLE DE CATAMARCA| ENCOMIENDAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":17056,"idioma_id":5,"titulo":"Evaluación del uso de diferentes antenas y la influencia de la no verticalidad en mediciones GPS","resumen":"En este trabajo se realizaron seis tests de mediciones episódicas GPS, con 48 horas de observación, cuyo objetivo es el de evaluar la repetividad de una posición al usar diferentes modelos de antenas y estimar la influencia de la no verticalidad en las coordenadas resultantes. El requerimiento de obtener posicionamientos precisos en estudios de la dinámica de la Tierra, donde los fenómenos que se quieren observar producen efectos de apenas unos milímetros, lleva a considerar factores importantes como el tipo de antena a utilizar, evitar inclinaciones en la monumentación y la aplicación de los archivos de correcciones a los centros de fases de las antenas. Las observaciones GPS fueron procesadas con el software Bernese v5.0, utilizando distintos observables, pseudo-observables y estimación de parámetros troposféricos. La comparación entre antenas mostró resultados con diferencias significativas, de 3 a 5 cm en la componente Vertical, principalmente cuando se utilizan antenas aptas para uso topográfico o cartográfico (Trimble Zephyr), en redes de líneas de base mayores a 1000 km, con soluciones de la combinación libre de ionósfera con estimación de parámetros troposféricos (L3+Tropo). En líneas de base cortas (aproximadamente 200 m) y procesamientos de simple frecuencia L1, las diferencias en la componente Vertical resultaron con valores entre 0,02 cm y 0,1 cm. En el caso en que la monumentación fue inclinada aproximadamente 5º en la dirección norte, se observó una variación de las coordenadas del orden de 1 cm en la componente Norte, dirección de la inclinación.","palabras_clave":"GPS|GEODESIA SATELITAL|POSICIONAMIENTO PRECISO|CAMBIO DE ANTENAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":17060,"idioma_id":5,"titulo":"Repensar el conflicto sindical latinoamericano frente a las estrategias del capital transnacional","resumen":"Labour movements in Latin America are facing a new crossroads due to socioeconomic and political changes that affect the place and the forms of conflict. The reintroduction of state intervention under neodevelopmental governments has proven insufficient to change the productive structure and the balance of power in labour-capital relations. The expansion of transnational capital pushes unions to re-evaluate strategies which were historically conditioned by corporativist arrangements centered on the State. The growth, transnationalization and concentration of capital creates a novel context that challenges the capacity of conventional corporativism to respond to these circumstances. Based on the work of authors Nicos Poulantzas and Antonio Gramsci, this paper discusses the current debates about capital-labour relations and the role of the State, with a centre on the issue of conflict and it is shape in the present economic context.","palabras_clave":"UNION|CONFLICT|STATE|MULTINATIONAL COMPANIES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":17079,"idioma_id":5,"titulo":"PLANTAS MEDICINALES COMERCIALIZADAS EN LA CIUDAD DE S. S. DE JUJUY (JUJUY, ARGENTINA) Y SU CALIDAD BOTANICA","resumen":" Resumen: Doce especies medicinales (Matricaria chamomilla, Senna alexandrina, Equisetum giganteum, Tilia cordata, Valeriana officinalis, Malva sylvestris, Illicium verum, Peumus boldus, Picrasma excelsa, Borago officinalis, Passiflora caerulea y Baccharis articulata), las más comercializadas en la ciudad de San Salvador de Jujuy, fueron evaluadas según sus modos de comercialización, su calidad botánica, sus usos y rol en la medicina urbana. Se relevaron 31 sitios de expendio para la obtención de muestras representativas, posteriormente se realizó un análisis macroscópico, y en complementación, una indagación bibliográfica. Los resultados indicaron que estas especies son comercializadas incumpliendo normativas vigentes de presentación y rótulo. La mitad de las muestras evidencian signos de adulteración. Si bien estas especies son de amplia difusión y consumo, en pocas sus usos han sido validados por la literatura etnofarmacológica. Se concluye que esto podría generar un descreimiento en la fitoterapia. ","palabras_clave":"medicinales|medicina andina|etnobotánica urbana|productos comercializados"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":17099,"idioma_id":4,"titulo":"Selection of Bacillus thuringiensis strains toxic to cotton boll weevil (Anthonomus grandis, Coleoptera: Curculionidae) larvae","resumen":"Preliminary bioassayswith whole culture (WC) of 124 Bacillus thuringiensis strains wereperformed with neonate larvae of Anthonomus grandis, a major cotton pest in Argentinaand other regions of the Americas. Three exoticand four native strains were selected for causing more than 50% mortality. Allof them were â-exotoxin producers.The native strains shared similar morphology of parasporal crystals, similarprotein pattern and identical insecticidal gene profiles. These features resembled toLepidoptera-toxic strains. Furthermore these strains showed aRep-PCR pattern identical to the lepidoptericidal strain HD-1, suggesting thatthese strains may belong to the serovar kurstaki. However, some differences appeared in theplasmid profiles and in the production of â-exotoxin. To determine the culture fractions where theinsecticidal metabolites were present, bioassays including resuspendedspore-crystal pellets, filtered supernatants (FS) were compared with that ofWC. Both fractions tested showed some level of insecticidal activity. Theresults may suggest that the main toxic factors can be found in FS and could bedirectly correlated with the presence of â-exotoxin. According to the bioassays with FS andautoclaved FS, the participation of thermolabile virulence factors such asCry1I in toxicity is not discarded too. In the selected strains, the majorassociated virulence factor would be the â-exotoxin, so their use in biological control of A. grandis should be restricted.Nevertheless, these strains could be the source of genes (e.g cry1Ia) to produce transgenic cottonplants resistant to this pest.","palabras_clave":"ANTHONOMUS GRANDIS | CRY1IA| BETA-EXOTOXIN|BACILLUS THURINGIENSIS |VIRULENCE FACTORS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":17938,"idioma_id":4,"titulo":"Influences of Secondary Phases on Ferroelectric Properties of Bi(Na,K)TiO3 Ceramics","resumen":"The effects of secondary phases on ferroelectric properties of Bi0.5Na0.5TiO3 (BNT) have been studied. Ceramic powders were prepared by solid state reaction employing different sintering temperatures and characterized by X-ray diffraction (XRD), Scanning Electron Microscopy and impedance spectroscopy. The perovskite structure was detected by XRD; together with small peaks corresponding to a secondary phase assigned to the Na2Ti6O13-based phase in calcined powders. In addition, morphology and the content of the secondary phase were modified by the sintering temperatures, affecting the ferroelectric properties, and ac and dc conductivities. We believe that our results can benefit not only the understanding of BNT ceramics, but also expand the range of applications.","palabras_clave":"Powders: solid state reaction|Ferroelectric properties|Piezoelectric properties|Perovskites"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":19941,"idioma_id":4,"titulo":"A mathematical method for parameter estimation in a tumor growth model","resumen":"In this paper, we present a methodology for estimating the effectiveness of a drug, an unknown parameter that appears on an avascular, spheric tumor growth model formulated in terms of a coupled system of partial differential equations (PDEs). This model is formulated considering a continuum of live cells that grow by the action of a nutrient. Volume changes occur due to cell birth and death, describing a velocity field. The model assumes that when the drug is applied externally, it diffuses and kills cells. The effectiveness of the drug is obtained by solving an inverse problem which is a PDE-constrained optimization problem. We define suitable objective functions by fitting the modeled and the observed tumor radius and the inverse problem is solved numerically using a Pattern Search method. It is observed that the effectiveness of the drug is retrieved with a reasonable accuracy. Experiments with noised data are also considered and the results are compared and contrasted.","palabras_clave":"AVASCULAR TUMOR|PDE-CONSTRAINED OPTIMIZATION|INVERSE PROBLEM|MATHEMATICAL MODELING"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":20229,"idioma_id":4,"titulo":"The Modal Logic of Copy and Remove","resumen":"We propose a logic with the dynamic modal operators copy and remove. Thecopy operator replicates a given model, and the remove operator removes paths in a given model. We show that the product update by an action model in dynamic epistemic logic decomposes in copy and remove operations, when we consider action models with Boolean pre-conditions and no post-condition. We also show that copy and remove operators with paths of length 1 can be expressed by action models with post-conditions. We investigate the expressive power of the logic with copy and remove operations, together with the complexity of the satisfiability problem of some of its syntactic fragments.","palabras_clave":"MODAL LOGIC|DYNAMIC EPISTEMIC LOGIC|EXPRESSIVITY|COMPLEXITY"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":20493,"idioma_id":4,"titulo":"Semi Industrial Drying of Vegetables in Quebrada de Humahuca Using An Array Of Large Solar Air Collector","resumen":"The design, structure, and evaluation of an indirect solar tunnel dryer of the air forced convection type are presented. The solar dryer was built and tested in Huacalera, Quebrada de Humahuaca, operated by a cooperative of small agricultural producers. The dryer consisted in a tunnel chamber of 450 kg load capacity and a bank of 10 solar collectors of 9.75 m long each. The collectors allowed temperatures in the drying chamber above 50 °C for 6 hours, requiring mixing with ambient air to produce the correct temperature for drying vegetables. During without load tests, with minimum air flow, 0.06 kg\/s, a maximum rank of outlet temperatures of 80-90 °C and temperature differences of 50-60 °C were obtained. The dryer was operated with different vegetables, obtaining good quality products in approximately one and a half day of sun. The optimum point of the collector behavior was determined with 0.4 kg\/s of air flow, and lower than 0.23 kg\/s is needed to work near to the 50 °C of outlet temperature. It was also performed a financial evaluation of the dryer, eflecting that the investment return rate of the device was around one year. In the Huacalera area, due to the gusts of winds and the day-night thermal amplitude, solar drying practice to semi-industrial scale was feasible with this kind of technology","palabras_clave":"Solar dryer|Drying of vegetables|Large solar collector"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":20767,"idioma_id":4,"titulo":"Compact homogeneous Riemannian manifolds with low co-index of symmetry","resumen":" We develop a general structure theory for compact homogeneous Riemannianmanifolds in relation to the co-index of symmetry. We will then use these resultsto classify irreducible, simply connected, compact homogeneous Riemannian mani-folds whose co-index of symmetry is less or equal than three. We will also constructmany examples which arise from the theory of polars and centrioles in Riemannian symmetric spaces of compact type. ","palabras_clave":"INDEX|SYMMETRY|COMPACT|HOMOGENEOUS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":20771,"idioma_id":4,"titulo":"Dynamical Sampling","resumen":"Let Y={f(i),Af(i),. .,Alif(i):i&#8712;&#937;}, where A is a bounded operator on &#8467;2(I). The problem under consideration is to find necessary and sufficient conditions on A,&#937;,{li:i&#8712;&#937;} in order to recover any f&#8712;&#8467;2(I) from the measurements Y. This is the so-called dynamical sampling problem in which we seek to recover a function f by combining coarse samples of f and its futures states Alf. We completely solve this problem in finite dimensional spaces, and for a large class of self adjoint operators in infinite dimensional spaces. In the latter case, although Y can be complete, using the Müntz-Szász Theorem we show it can never be a basis. We can also show that, when &#937; is finite, Y is not a frame except for some very special cases. The existence of these special cases is derived from Carleson´s Theorem for interpolating sequences in the Hardy space H2(D). Finally, using the recently proved Kadison-Singer\/Feichtinger theorem we show that the set obtained by normalizing the vectors of Y can never be a frame when &#937; is finite.","palabras_clave":"Sampling Theory|Frames|Sub-Sampling|Reconstruction|Müntz-Szász Theorem|Feichtinger conjecture|Carleson's Theorem"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":20794,"idioma_id":4,"titulo":"Bird fruit consumption results from the interaction between fruit-handling behaviour and fruit crop size","resumen":"Bird foraging behaviour is a major factor involved in mutualistic interactions of fleshy-fruited plants. Despite much research, we still lack quantified demonstrations of how fruit display traits affect fruit removal behaviour. Although the fruit crop size hypothesis proposes a general mechanism for fruit trait selection, it overlooks the fact that distinctive bird behaviours in a bird assemblage would have different effects on fruit crop size. Here, we show that the relevance of fruit crop size for bird fruit consumption is driven by two basic components of fruit foraging behaviour: fruit handling and residence time. We assessed bird fruit-eating behaviour (fruit consumption, fruit handling and residence time) and its relationship with fruit crop size, taking into account body size and spatial focal context (conspecific neighbour density and distance to the forest edge from individual plants) in a population of Vassobia breviflora (Solanaceae) in Tucumán, Argentina. At the assemblage level, fruit consumption was positively related to fruit crop size and residence time, and the interaction between fruit crop size and residence time depended on fruit-handling behaviour. At the functional group level, both gulpers and pulp consumers showed a positive relationship between fruit consumption and residence time. However, gulpers showed a negative interaction between fruit crop size and residence time, while pulp consumers showed no interaction. At the species level, fruit consumption by Turdus rufiventris (gulper) was positively related to fruit crop size, whereas fruit consumption by Thraupis sayaca and Zonotrichia capensis (pulp consumers) depended positively on residence time. Essentially, gulpers spent short residence times in plants with larger fruit crops, whereas pulp consumers spent long residence times in plants regardless of fruit crop size. The segregation between fruit-eating behaviours and their relationship with fruit crop size suggests that bird functional groups (i.e. gulpers and pulp consumers) would shape fruit display traits with different intensities.","palabras_clave":"Frugivory|Seed dispersal mutualism|Fruit-handling behaviour|Fruit crop size"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":21179,"idioma_id":4,"titulo":"Spermatogenesis in the parasitoid Diachasmimorpha longicaudata (Hymenoptera, Braconidae)","resumen":"The study of spermatogenesis in Hymenoptera is limited to few taxa due to limitations to access the material in the right stage for analysis. The information available up to now states that the gametogenesis in males involves a modified meiosis, similar to mitosis. This is due to the haplodiploid sex determination system present in the order, where females are diploid and males are haploid. In the present work, we examined the spermatogenesis process in the parasitoid Diachasmimorpha longicaudata (Ashmead) (Hymenoptera: Braconidae). We performed squash preparations from testes of individuals from the third larval instar until the adult stage. Some cytological traits, such as the presence of a monopolar spindle, were analysed in detail by means of histological semi-thin sections. The spermatogenesis in this species comprises an abortive first division with the formation of ananucleated cytoplasmic bud and a nucleated cell, and an equal second division of the nucleated cell, leading to the generation of two mature spermatozoa. The results presented herein provide more information about the process of spermatogenesis in Hymenoptera, which has not been studied in depth in parasitic species.","palabras_clave":"HYMENOPTERA|MODIFIED MEIOSIS|ABORTIVE DIVISION|SPERMATOGENESIS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":21191,"idioma_id":4,"titulo":"Squamocin, an annonaceous acetogenin, enhances the degradation of naphthalene mediated by Bacillus atrophaeus CN4","resumen":"Abstract Squamocin belongs to a group of compounds called annonaceous acetogenins.They are secondary products of Annonaceae metabolism and can be isolated from Annonacherimolia seeds. This paper deals with the stimulation of biofilm formation of Bacillusatrophaeus CN4 by employing low squamocin concentrations to increase naphthalene degradation.Bacillus atrophaeus CN4, isolated from contaminated soil, has the ability to degradenaphthalene as the only source of carbon and energy. In the absence of additional carbonsources, the strain removed 69% of the initial concentration of naphthalene (approx. 0.2 mmol\/l)in the first 12 h of incubation. The addition of squamocin in LB medium stimulated Bacillusatrophaeus CN4 biofilm formation and enhanced naphthalene removal. Squamocin (2.5 g\/ml)does not affect planktonic growth and therefore, the observed increases are solely due to thestimulation of biofilm formation.© 2017 Asociaci´on Argentina de Microbiolog´&#305;a. Published by Elsevier Espa?na, S.L.U. This is anopen access article under the CC BY-NC-ND license (http:\/\/creativecommons.org\/licenses\/bync-nd\/4.0\/).","palabras_clave":"SQUAMOCIN|ANNONACEOUS ACETOGENINS| NAPHTHALENE|BACILLUS ATROPHAEUS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":21193,"idioma_id":4,"titulo":"On the use of stochastic ranking for parent selection in differential evolution for constrained optimization","resumen":"The role of parent selection is to distinguish between individuals based on their quality. Parent selection has been a key component in the design of evolutionary algorithms, since it is partially responsible for improving the quality of the population. Stochastic ranking is quite a successful approach for evolutionary constrained optimization, and has usually been employed during the survival selection process. This paper provides the first insight into the use of the stochastic ranking procedure during the parent selection mechanism in the design of new evolutionary algorithms for constraint handling. We adopted differential evolution as the base algorithm, mainly because of its outstanding performance in continuous optimization found in literature. We undertake seven experiments in order to validate our proposal. The results indicate that our proposed approach is able to find solutions that are competitive with respect to other recently proposed approaches, but uses a fraction of the required computational effort. Furthermore, our proposal can easily be incorporated into any probabilistic evolutionary algorithm that is based on parent selection.","palabras_clave":"xx"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":21286,"idioma_id":4,"titulo":"Mechanical behavior of fibers and films based on PP\/quartz composites","resumen":"In this work, films and fibers of Polypropylene basedcomposites reinforced with quartz were investigated. The materials were processedin a twin screw extruder with filler contents of 1, 2.5, 5 wt.%. Morphology,thermal properties and mechanical behavior of these materials were studied. A homogeneous filler dispersionand particle alignment in the extrusion direction was detected for the films. Thermogramsdisplayed a marginal nucleating effect of quartz particles. Uniaxial tensiletests indicated a high ductility level and strain hardening for the compositesprocessed as films (in the extrusion direction). Single fiber tests displayedimproved tensile properties compared to the same materials produced as films. Quasi-staticfracture tests showed a completely ductile behavior for the films in theextrusion direction. In addition, films fracture toughness was found toincrease with filler content.","palabras_clave":"POLYPROPYLENE FIBERS|DRAWING|MECHANICAL PROPERTIES|THERMAL PROPERTIES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":21323,"idioma_id":4,"titulo":"Requirement of an early activation of BDNF\/c-Fos cascade in the retrosplenial cortex for the persistence of a long-lasting aversive memory","resumen":"During the past few years there has been growing interest in the role of the retrosplenial cortex (RSC) in memory processing. However, little is known about the molecular changes that take place in this brain region during memory storageformation. In the present work, we studied the early posttraining participation of RSC in the formation and storage of a long-lasting memory in rats. We found an increase in c-Fos levels in the anterior part of the RSC (aRSC) after inhibitory avoidance (IA) training. Interestingly, this increase was associated with memory durability, since blocking c-Fos expression using specific antisense-oligonucleotides (ASO) impaired long-lasting retention 7 days after training without affecting memory expression 2 days after training. In addition, we showed that BDNF is one of the upstream signals for c-Fos expression required for memory persistence, since blocking BDNF synthesis prevents IA training induced-increase in c-Fos levels in aRSC and affects memory persistence. In addition, we found that injection of BDNF into aRSC around training was sufficient to establish a persistent memory and that this effect was prevented by c-fos ASO infusion into the same structure. These findings reveal an early posttraining involvement of aRSC in the processing of a long-lasting aversive memory.","palabras_clave":"c-fos|BDNF|IA|memory"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":21838,"idioma_id":5,"titulo":"Caracterización de cepas de Escherichia coli patógeno extraintestinal aislados de perros y gatos de Buenos Aires, Argentina","resumen":"El pangenoma de Escherichia coli se compone de un core conservado y regionesgenómicas variables. El componente genético constante permite determinar la filogeniadel microorganismo, mientras que la variabilidad genética ha permitido el surgimiento decepas patógenas intestinales y extraintestinales. En este estudio caracterizamos genéticamente85 cepas patógenas extraintestinales aisladas de caninos y felinos. Se utilizó el esquema deClermont para agruparlas en relación con el filogrupo de pertenencia (intestinal: A y B1; extraintestinal:B2 y D) y se investigó en ellas la presencia de varios marcadores de virulencia (pap1-2,pap3-4, sfa, afa, hlyA, aer y cnf), así como de marcadores de patovares híbridos. El 69,4% delos aislamientos pertenecieron al filogrupo A; el 1,2% al B1; el 16,5% al B2 y el 12,9% al D. El genencontrado con mayor frecuencia fue sfa (21\/85), seguido de los genes pap1-2 y cnf (20\/85) ypap3-4 (19\/85). No se detectaron híbridos. Los aislamientos en animales deben ser estudiadosdebido al potencial zoonótico del microorganismo.","palabras_clave":"UPEC|FILOGRUPOS|FACTORES DE VIRULENCIA|ANIMALES DOMESTICOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":21859,"idioma_id":4,"titulo":"Finite-dimensional pointed Hopf algebras over finite simple groups of Lie type I . Non-semisimple classes in PSL(n,q)","resumen":"We show that Nichols algebras of most simple Yetter-Drinfeldmodules over the projective special linear group over a finite field, corresponding to semisimple orbits, have infinite dimension. We introduce a new criterium to determine when a conjugacy class collapses and prove that for infinitely many pairs (n, q), any finite-dimensionalpointed Hopf algebra H with G(H) &#8771; PSLn(q) or SLn(q) is isomorphicto a group algebra.","palabras_clave":"Nichols algebra|Yetter-Drinfeld module|Hopf algebra|Racks"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":21974,"idioma_id":4,"titulo":"Direct reciprocity in animals: The roles of bonding and affective processes","resumen":"The presence of direct reciprocity in animals is a debated topic, because, despite its evolutionary plausibility, it is believed to be uncommon. Some authors claim that stable reciprocal exchanges require sophisticated cognition which has acted as a constraint on its evolution across species. In contrast, a more recent trend of research has focused on thepossibility that direct reciprocity occurs within long-term bonds and relies on simple as well as more complex affective mechanisms such as emotional book-keeping, rudimentary and higher forms of empathy, and inequity aversion, among others. First, we present evidence supporting the occurrence of long-term reciprocity in the context of existing bondsin social birds and mammals. Second, we discuss the evidence for affective responses which, modulated by bonding, may underlie altruistic behaviours in different species. We conclude that the mechanisms that may underlie reciprocal exchanges are diverse, and that some act in interaction with bonding processes. From simple associative learning in socialcontexts, through emotional contagion and behavioural mimicry, to empathy and a sense of fairness, widespread and diverse social affective mechanisms may explain why direct reciprocity may not be a rare phenomenon among social vertebrates.","palabras_clave":"Porsocialidad|Reciprocidad|Justicia|Empatía"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":21990,"idioma_id":4,"titulo":"Microvertebrates preserved in mammal burrows from the Holocene of the Argentine  Pampas: a taphonomic and paleoecological approach","resumen":"Microvertebrates are a major component of many assemblages recovered from the Quaternary of the Argentine Pampas. The main goal of this paper is to analyse the taphonomic history of a Holocene microfossil bonebed, recovered from the infilling of a burrow. Evidences suggest the plains vizcacha Lagostomus maximus as the putative producer of the burrow. The assemblage includes individuals belonging to different taxa of mammals (marsupials and rodents) and reptiles (snakes). Taphonomic features suggest that the accumulation inside the burrow was related to flooding processes in the plain. The burrow was a natural trap that favoured the accumulation and preservation of remains corresponding to individuals from different sources. According to the taphonomic evidence, some individuals (Lagostomus maximus, Lestodelphys halli and Serpentes indet.) died inside the burrow, whereas others (Microcavia australis, Reithrodon auritus and Ctenomys sp.) died outside the burrow, and after a time of being exposed on the surface their remains were transported by surface run-offs into the burrow. The record of Lestodelphys halli and Serpentes indet. in the burrow produced by Lagostomus maximus could be related to a circumstantial use. Mammal burrows are a significant taphonomic mode for the late Cenozoic of the Argentine Pampas.","palabras_clave":"taphonomy|microvertebrates|mammal burrows|natural traps"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":22439,"idioma_id":4,"titulo":"Oxidative stress indicators in populations of the gastropod Buccinanops globulosus affected by imposex","resumen":"The gastropod Buccinanops globulosus is commonly used as bioindicator of tributyltin (TBT) contamination due to its high imposex incidence in maritime traffic areas. The aim of this study was to evaluate both oxidative stress in B. globulosus at three sites with different maritime activity, and imposex incidence in Nuevo gulf, Argentina.Oxidative stress parameters in digestive glands, like superoxide dismutase (SOD) and glutathione-S-transferase (GST) activities, reduced glutathione levels (GSH), and oxidative damage to lipids, estimated as thiobarbituric acid reactive substances(TBARs) as well as imposex parameters (% imposex and female penis length -FPL-) were measured in females. Gastropods from the harbour area showed 100% imposex, the highest FPL and TBARs content, as well as GSH levels and SOD activity.The different oxidative stress responses and high imposex incidence at the harbour site may indicate a negative effect on the organism´s physiological state due to environmental pollution.","palabras_clave":"OXIDATIVE STRESS|IMPOSEX|MARINE POLLUTION|BUCCINANOPS GLOBULOSUS| NASSARIIDAE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":22527,"idioma_id":4,"titulo":"Synaptosomal bioenergetic defects are associated with cognitive impairment in a transgenic rat model of early Alzheimer's disease","resumen":"Synaptic bioenergetic deficiencies may be associated with early Alzheimer´s disease (AD). To explore this concept, we assessed pre-synaptic mitochondrial function in hemizygous (+\/-)TgMcGill-R-Thy1-APP rats. The low burden of A&#946; and the wide array of behavioral and cognitive impairments described in 6-month-old hemizygous TgMcGill-R-Thy1-APP rats (Tg(+\/-)) support their use to investigate synaptic bioenergetics deficiencies described in subjects with early Alzheimer´s disease (AD). In this report, we show that pre-synaptic mitochondria from Tg(+\/-) rats evidence a decreased respiratory control ratio and spare respiratory capacity associated with deficits in complex I enzymatic activity. Cognitive impairments were prevented and bioenergetic deficits partially reversed when Tg(+\/-) rats were fed a nutritionally complete diet from weaning to 6-month-old supplemented with pyrroloquinoline quinone, a mitochondrial biogenesis stimulator with antioxidant and neuroprotective effects. These results provide evidence that, as described in AD brain and not proven in Tg mice models with AD-like phenotype, the mitochondrial bioenergetic capacity of synaptosomes is not conserved in the Tg(+\/-) rats. This animal model may be suitable for understanding the basic biochemical mechanisms involved in early AD.","palabras_clave":"amiloide beta|enfermedad de Alzheimer|neurodegeneración |sinaptosomas"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":22652,"idioma_id":4,"titulo":"Post-hatching development of the ornamental ?Red Cherry Shrimp? Neocaridina davidi (Bouvier, 1904) (Crustacea, Caridea, Atyidae) under laboratorial conditions","resumen":"The ?Red Cherry shrimp?, Neocaridina davidi is a small freshwater caridean shrimp living, originally, in various kinds of inland water bodies around Asian countries.This shrimp has reached several countries for ornamental use; however,basic information on the biology of the species is still scarce in the literature.Its early postembryonic development morphology has not yet been described. This paper focused onthe production and the development of early post-hatching stages of N. davidi, its malesecondary sexual features, observation of the gonads and the presence of females withembryos. The larval development of N. davidi was almost suppressed as noted by thepresence of relatively large-sized eggs, first stage hatching as adecapodid; and the tail fans were present only from the 2nd post-hatching stage. Abiological important consequence of the presence of this Red Cherry shrimp species inthe Neotropics is its potential release into nature, which could cause its rapid dispersion affecting populations of other indigenous caridean freshwater shrimps.","palabras_clave":"Atyidae|NEOCARIDINA|POST HATCHING|FEEDING"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":22748,"idioma_id":4,"titulo":"INDIVIDUAL AND COMBINED EFFECTS OF POMEGRANATE EXTRACT AND ULTRASONIC TREATMENTS ON KIWIFRUIT JUICE QUALITY PARAMETERS","resumen":"The objectives of this study were to report the effectiveness of ultrasound andpomegranate extract, individually and combined, on kiwifruit juice qualityattributes. Fruit juices were treated with 180 lg\/mL pomegranate extract andsonicated for 10 and 30 min (180 W, 40 kHz). Microbial populations, ascorbic acid retention, sensory attributes and color parameters were evaluated throughrefrigerated storage. By the end of storage, individual ultrasound treatmentswere able to reduce yeast and molds counts compared with that in control.Furthermore, combined treatments of ultrasound and pomegranate extract showedsynergism, with higher reductions on yeast and molds. None of the treatments were able to increase the ascorbic acid retention through storage time. Color parameters evaluated showed that the treatments applied had significant differences from that of control. At Day 2, the treatments showed an improvement in color, with total color difference (DE) lower than that of untreated sample, indicating less color difference from fresh kiwifruit juice. Sensory attributes were not significantly affected by the treatments. However, a significant effect of storage time was perceived by the panelists, with a decrease in overall visual quality score throughout time, indicating the end of shelf-life of the product at Day 7 of refrigerated storage","palabras_clave":"FRUIT JUICES|ULTRASOUND|BIOPRESERVATIVES|POMEGRATE EXTRACTS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":23070,"idioma_id":5,"titulo":"Analisis de caries en superficies  de la corona dentaria: Estudio en una colección osteológica humana documentada","resumen":"La caries es una enfermedad cuya etiología ha sido recurrentemente estudiada. El accionar bacteriano produce una desmineralización que conduce, en caso de no ser tratada, a la pérdida de la pieza dentaria. Esta patología presenta un patrón de incidencia característico, tanto a nivel poblacional como individual. Si bien muchos estudios se han centrado en el impacto de esta patología en las piezas dentarias, los análisis en relación a la frecuencia de caries por superficie en colecciones osteológicas documentadas no son tan numerosos. En el presente trabajo se realizará un análisis de frecuencia de caries por tipo de diente y por ubicación en la superficie del esmalte dentario en una muestra perteneciente a la Colección Lambre (FCM, UNLP). Se realizó un análisis macroscópico en busca de caries relevando la misma por tipo de diente (anterior\/posterior) y por ubicación en la corona dentaria (mesial\/distal\/lingual\/labial\/oclusal). Se encontró que los dientes posteriores fueron los más afectados y la cara oclusal fue la superficie del esmalte dental con mayor presencia de caries. Las diferencias entre las proporciones de caries en dientes posteriores y anteriores resultaron ser significativas, así como también lo fueron las diferencias entre las superficies de la corona dentaria. Los resultados aquí obtenidos coinciden con la mayoría de los estudios realizados tanto en restos arqueológicos, contemporáneos, como también con aquellos estudios epidemiológicos provenientes de casos clínicos.","palabras_clave":"CARIES|COLECCION|OSTEOLOGICA|ESMALTE|SUPERFICIE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":23398,"idioma_id":5,"titulo":"Valorización económica, social y ambiental de la desertificación en el Departamento Santa María, provincia de Catamarca","resumen":"Este trabajo presenta los resultados del estudio de valorización integral de la desertificación en el departamento Santa María,provincia de Catamarca. El método de valorización utilizado combina herramientas de la economía ambiental y economíaecológica, realizando un análisis de todo el sistema, a través de la integración de resultados. El trabajo desarrolló un métodopara valorar la pérdida de secuestro de carbono en la cuenca entre 1997 y 2012. Los resultados obtenidos indican que ladesertificación ha aumentado en el todos los casos, excepto en una localidad. Se evidencia también, problemassocioeconómicos, como bajos ingresos, alto porcentaje de población que vive bajo la línea de pobreza e indigencia, como asíescaza capacitación de los pobladores en temas ambientales y baja percepción de la desertificación como un problema. Laspérdidas por desertificación representan un 2.4% del Producto Bruto Geográfico de la provincia. Las emisiones de CO2, de lacuenca, representan el 0,14% de las emisiones del país como consecuencia de los procesos de deterioro ambiental que sehan producido en la zona. Todos estos resultados indican que se necesitan medidas urgentes para revertir estos procesos.","palabras_clave":"Desertificación|Valoración económica"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":23709,"idioma_id":4,"titulo":"The first human settlement of the New World: A closer look at craniofacial variation and evolution of early and late Holocene Native American groups","resumen":"During its expansion across the globe, Homo sapiens successfully survived to major adaptive challenges as a species, inviting scientific research to plunge into the particularities of continental settlement dynamics. A recurrent paleoanthropological concern is about the understanding of the great deal of craniofacial diversity that evolved into the Americas, which includes a vector of continuum variation between a generalized morphology observed among humans groups leading the Out-of-Africa dispersion, and a derived set of craniofacial traits classically labeled as ?mongoloid? and that would have arise in Asia during the Holocene. Here, we use geometric morphometric techniques and multivariate statistics along with quantitative genetic approaches to look more closely into the human craniofacial evolutionary history during the Late PleistoceneeEarly Holocene from Asia and the New World. We detected significant signals of deviation of the neutral evolutionary expectations, suggesting an important action of non-stochastic evolution (e.g. natural selection, phenotypic plasticity) in the Americas. We also found further support to the Recurrent Gene Flow model that refers to an ancestral, founder population experiencing a standstill in Beringia, and exhibiting high within-group craniofacial variation. This original, internally variable stock would have been the ancestral source of variation that fuelled the subsequent local micro evolution of other derived phenotypic patterns, giving origin to the craniofacial diversity observed among Holocene Native American samples. © 2015 Elsevier Ltd and INQUA.","palabras_clave":"GEOMETRIC MORPHOMETRICS|QUANTITATIVE GENETICS|NEW WORLD SETTLEMENT|CRANIOFACIAL EVOLUTION|PALEOAMERICANS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":23980,"idioma_id":4,"titulo":"The controversy space on Quaternary megafaunal extinctions","resumen":"In this work, we analyze the origin and development of the debate on megafaunal extinctions using the Controversy Space Model (CSM). The CSM is composed of a common ground of theoretical agreements and a dialectical dynamic of disputes regarding the causes of extinction, called refocalization, identifying phases of conceptual blockage and unblockage. The hypotheses are clustered in three major groups, according to causes of extinction: anthropic, biotic, and environmental. We argue that the evolution of the controversy space follows a succession of questions relevant to each period, the answers to which need to be settled to allow the debate to move forward. We postulate that nowadays this controversy space is suffering a period of conceptual blockage. This may be because authors are assembled around two major paradigms: environmental versus anthropic causes. Each of these two theoretical positions looks at a portion of reality that may be partially true, but incomplete in terms of a global theory of extinction. We propose that this conceptual blockage could be solved by developing a mathematical model in which each hypothesis plays a role in a mechanistic way. The relative importance of each hypothesis may vary depending on its respective context. It follows from this that it should not matter which cause is favored: the emphasis should be given to all causes acting together in a predictable manner.","palabras_clave":"Quaternary|Extinctions"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":23981,"idioma_id":4,"titulo":"On the roles of hunting and habitat size on the extinction of megafauna","resumen":"We study a mechanistic mathematical model of extinction and coexistence in a generic hunter-prey ecosystem. The model represents typical scenarios of human invasion and environmental change, characteristic of the late Pleistocene, concomitant with the extinction of fauna in many regions of the world. As a first approach we focus on a small trophic web of three species, including two herbivores in asymmetric competition, in order to characterize the generic behaviors. Specifically, we use a stochastic dynamical system, allowing the study of the role of fluctuations and spatial correlations. We show that the presence of hunters drives the superior herbivore to extinction even in habitats that would allow coexistence, and even when the pressure of hunting is lower than on the inferior one. The role of system size and fluctuating populations is addressed, showing an ecological meltdown in small systems in the presence of humans. The time to extinction as a function of the system size, as calculated with the model, shows a good agreement with paleontological data. Other findings show the intricate play of the anthropic and environmental factors that may have caused the extinction of megafauna.","palabras_clave":"Extinctions|Megafauna"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":24015,"idioma_id":4,"titulo":"Role of M3 muscarinic acethylcholine receptor antibodies as a new marker in Sjögren Syndrome","resumen":"This paper investigates the presence of M3 muscarinic acetylcholine receptor autoantibody present in the serum of patients with primary SjÖgren syndrome (pSS). Main methods: We detected the levels of M3mAChR peptide IgG, PGE2, IL-1&#946; in serum of SS patients using the enzyme-linked immune sorbent assay (ELISA). To measure the quantity of nitrite\/nitrate, we used Griess reagent system. Key findings: Titres of M3mAChR antibody in sera from SS patients are significantly enhanced compared to healthy subjects (control). The enhancement of these autoantibodies is accompanied by the increase of the levels of PGE2, IL-1&#946; and nitrite\/nitrate in serum. Under in vitro conditions, the synthetic human M3 peptide impaires the increment of M3mAChR antibody but not that of nati-Ro\/SSA antibody. In positive anti-Ro\/SSA antibody patients, the increment of M3mAChR peptide IgG and the measured pro-inflammatory substances is related. Significance: On this basis, anti M3mAChR peptide IgG can be said to act as a modulator of the immune system and to play a role in the host-chronic increment of proinflammatory substances in SS patients with positive Ro\/SSA antibody. This association between the antibody and the pathogenesis of SS disease may result in useful predicting SS.","palabras_clave":"ANTI-RO\/SSA ANTIBODY|ANTI-M3 ACHR PEPTIDE|IL-1BETA|PGE2"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":24052,"idioma_id":4,"titulo":"Plasma and tissue clindamycin antimicrobial activity after parenteral administration to cats under surgical conditions","resumen":"Clindamycin plasma and tissue disposition in cats under surgical conditions after a single intravenous (IV), intramuscular (IM) and subcutaneous (SC) administration at a dose rate of 10 mg\/kg were studied. After intravenous, intramuscular and subcutaneous administration, peak plasma concentrations were 10.93±3.78 µg\/mL (Cp(0)), 5.93±1.18 µg\/mL (Cmax)) and 6.30±0.88 µg\/mL (Cmax)), respectively. Eight hours after clindamycin IV, IM and SC administration plasma concentrations declined to 2.01±0.61 µg\/mL, 2.96±0.43 µg\/mL and 3.36±0.97 µg\/mL, respectively. Sixty to 90 minutes after clindamycin administration, tissue concentrations ranged from a minimum in subcutaneous tissue of 4.90 µg\/g (IV), 3.06 µg\/g (IM) and, 3.13 µg\/g (SC) to a maximum in uterus of 13.41 µg\/g (IV), 14.07 µg\/g (IM) and, 14.44 µg\/g (SC). The lowest tissue\/plasma concentration ratio for the three administration routes was observed in subcutaneous tissue, while the highest was observed at genital level (ovary for IV and IM and uterus for SC).Estimated efficacy predictor (AUC\/MIC), considering MIC breakpoint for bacteria isolated from animals, indicates that clindamycin administered IV, IM or SC at the studied dose is appropriated for perioperative prophylactic protocols and that given with a dose interval of 12 hours would be effective for susceptible infection treatment in cats.","palabras_clave":"CLINDAMYCIN|PHARMACOKINETICS|CAT|PARENTERAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":24202,"idioma_id":5,"titulo":"INFLAMACIÓN ESPINAL AGUDA NO IATROGÉNICA POS LAMINECTOMÍA EN RATAS","resumen":"La laminectomía en ratas es un procedimiento normalmente utilizado tanto en los diseñosexperimentales de funcionalidad medular como en aquellos de electrofisiología. También seha utilizado a la rata como modelo experimental de lesiones compresivas y traumáticas de lamédula espinal. Se realizaron laminectomías en ratas sanas anestesiadas y se cuantificó elgrado de respuesta inflamatoria medular luego del abordaje comparado con la respuesta enratas no operadas que fueron anestesiadas y fijadas de la misma manera. Se observó presenciade respuesta inflamatoria en los segmentos medulares expuestos y en aquellos ubicadoscraneal y caudalmente a la laminectomía.","palabras_clave":"LAMINECTOMIA|MIELITIS|RATAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":24207,"idioma_id":5,"titulo":"RESPUESTA MEDULAR A LA APLICACIÓN DE POLIETILENGLICOL LUEGO DEL TRAUMA MEDULAR AGUDO EXPERIMENTAL EN LA RATA","resumen":"La característica multivariada de las lesiones producidas por el Trauma Medular Agudo hace necesaria  la  utilización  de  modelos  animales  completos.  En  este  trabajo  se  estudia  el  efecto protector  del  polietilenglicol,  fusógeno  celular  de  mediano  peso  molecular,  en  la  médula espinal  traumatizada  de  ratas.  La  aplicación  inmediata  del  polietilenglicol  en  la  médula espinal  lesionada  produjo  una  significativa  disminución  de  los  signos  clínicos,  así  como también  una  disminución  de  los  indicadores  histopatológicos  de  respuesta  secundaria  al trauma  medular.  Se  discuten  los  resultados  obtenidos  comparándolos  con  diferentes  grupos control. Concluimos que el efecto neuroprotector del polietilenglicol aplicado en el sitio de la lesión arroja resultados que apoyan la necesidad de probar su efecto sistémico en animales de experimentalmente lesionados","palabras_clave":"TRAUMA MEDULAR AGUDO|RATAS|POLIETILENGLICOL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":24297,"idioma_id":5,"titulo":"Características Diagnósticas e Intervenciones Psicológicas para las Crisis No Epilépticas de Origen Psicógeno (CNEP)","resumen":"Las Crisis No Epilépticas Psicógenas (CNEP) representan un desafío clínico, debido a la complejidad de sus manifestaciones, etiología y comorbilidad. El objetivo de este artículo es presentar los tratamientos psicológicos disponibles para abordar y tratar las CNEP. Se ha llevado a cabo una búsqueda bibliográfica en las bases de datos Medline, Latindex, Redalyc, Cochrane Collaboration EBSCO y Lilacs. Dentro de los abordajes diseñados para el tratamiento de las CNEP, se destacan tres modelos de intervención psicoterapéutica que han obtenido resultados favorables en la puesta a prueba de sus intervenciones: dos modelos cognitivo conductuales y el tratamiento aumentado de Terapia Interpersonal. Se discuten estos hallazgos en función de las limitaciones, tanto metodológicas como provenientes de los distintos estudios clínicos encontrados.","palabras_clave":"CRISIS NO EPILÉPTICAS PSICÓGENAS|DIAGNÓSTICO|TRATAMIENTOS PSICOLÓGICOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":24394,"idioma_id":4,"titulo":"Emotion recognition in never-seen languages using a novel ensemble method with emotion profiles  (IF 2.675)","resumen":"Over the last years, researchers have addressed emotional state identification because it is an important issue to achieve more natural speech interactive systems. There are several theories that explain emotional expressiveness as a result of natural evolution, as a social construction, or a combination of both. In this work, we propose a novel system to model each language independently, preserving the cultural properties. In a second stage, we use the concept of universality of emotions to map and predict emotions in never-seen languages. Features and classifiers widely tested for similar tasks were used to set the baselines. We developed a novel ensemble classifier to deal with multiple languages and tested it on never-seen languages. Furthermore, this ensemble uses the Emotion Profiles technique in order to map features from diverse languages in a more tractable space. The experiments were performed in a language-independent scheme. Results show that the proposed model improves the baseline accuracy, whereas its modular design allows the incorporation of a new language without having to train the whole system.","palabras_clave":"Emotion Recognition|Ensemble Classifier|Emotion Profiles|Not-yet-encountered Languages"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":24419,"idioma_id":4,"titulo":"Cretaceous deformation of the southern Central Andes: synorogenic growth strata in the Neuquén Group (35º 30&#8242;-37ºS)","resumen":"The Neuquen Group is an Upper Cretaceous continental sedimentary unit exhumed during the latest Miocene contractional phase occurred in the southern Central Andes, allowing a direct field observation and study of the depositional geometries. The identification of growth strata on these units surrounding the structures of the frontal parts of the Andes, sedimentological analyses andU?Pb dating of detrital components, allowed the definition of a synorogenic unit that coexisted with the uplift of the early Andean orogen since ca. 100 Ma, maximum age obtained in this work, compatible with previous assignments and constrained in the top by the deposition of the Malarg?ue Group, in the Maastrichtian (ca. 72 Ma). The definition of a wedge top area in this foreland basin system, where growth strata were described, permitted to identify a Late Cretaceous orogenic front and foredeep area, whose location and amplitude contrast with previous hypotheses. This wedge top area was mostly fed from the paleo-Andes with small populations coming from sources in the cratonicarea that are interpreted as a recycling in Jurassic and Lower Cretaceous sections, which contrasts with other analyses performed at the foredeep zone that have mixed sources. In particular, Permian sources are interpreted as coming directly from the cores of the basement structures, where Neopaleozoicsections are exposed, next to the synorogenic sedimentation, implying a strong incision in Late Cretaceous times with an exhumation structural level similar to the present. The maximum recognised advance for this Late Cretaceous deformation in the study area is approximately 500 km east of the Pacific trench, which constitutes an anomaly compared with neighbour segments where Late Cretaceous deformations were found considerably retracted. The geodynamic context of thesedimentation of this unit is interpreted as produced under the westward fast moving of South America, colliding with two consecutive mid-ocean ridges during a period of important plate reorganisation. The subduction of young, anhydrous, buoyant lithosphere would have produced changes in the subduction geometry, reflected first by an arc waning\/gap and subsequently by an arc migrationthat coexisted with synorogenic sedimentation. These magmatic and deformational processes would be the product of a shallow subduction regime, following previous proposals, which occurred in Late Cretaceous times, synchronous to the sedimentation of the Neuquen Group.","palabras_clave":"tectonica|andes patagonicos"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":25258,"idioma_id":5,"titulo":"La materia primera y la forma corporeitatis en la física de Alberto Magno","resumen":"La física de Alberto Magno se centra sobre la base de una materialidad que no puede ser definida como pura potencialidad pues no podría explicarse la  continuidad y teleología propias de todo cambio sustancial. Por esto, en la   materia primera existen ciertas dimensiones cuantitativas indeterminadas que la hacen divisible y le permiten sustentar a la forma sustancial en el cambio.  Estas  dimensiones suponen la presencia de una primera formalidad en la materia, llamada forma corporeitatis, que hacen de la materia primera una realidad actualizada e independiente de la forma sustancial.","palabras_clave":"ALBERTO MAGNO|FÍSICA|MATERIA|FORMA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":25345,"idioma_id":5,"titulo":"Dimensiones de una masacre en la escuela: traducción intersemiótica en We need to talk about Kevin","resumen":"El presente trabajo aborda los procesos de transformación de la materia lingüística literaria en discurso cinematográfico a partir de un caso específico: We need to talk about Kevin, libro de Lionel Shriver y filme de Lynne Ramsay. Nos interesa, en primer lugar, centrarnos en las transformaciones que sufre la materia lingüística en su traducción intersemiótica a otra materialidad significante. Además, resulta pertinente, en segundo lugar, compartir algunas reflexiones sobre las disputas, consideradas en términos de lo político, en torno a la institución escolar construida en el libro y en el filme.","palabras_clave":"TRADUCCIÓN INTERSEMIÓTICA|MASACRES EN ESCUELAS|LO POLÍTICO|DISCURSO AUDIOVISUAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":25394,"idioma_id":5,"titulo":"'LA FORMACIÓN UNIVERSITARIA EN INSTITUIONES COMPLEJAS","resumen":"El punto de partida de este estudio1 es la institución universidad en relación con la formación en educa-ción física en Argentina a partir de los años noventa. Ese periodo instaura un cambio de época social y político que atraviesa a las instituciones de educación superior y a las experiencias de formación de los sujetos. Frente a ello, intento componer una visión actual de las instituciones formadoras, analizando las concepciones que diversos autores tienen sobre las mismas.","palabras_clave":"FORMACION  |UNIVERSIDAD|EDUCACION FISICA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":26070,"idioma_id":5,"titulo":"Los profesores frente a la nueva\/vieja escuela secundaria argentina","resumen":"El nivel secundario es actualmente objeto de múltiples transformaciones, políticas y debates. Se cuestiona su función histórica, la organización del curriculum, el trabajo de los docentes y de qué manera es posible dar sentido a la experiencia escolar de los adolescentes. El artículo presenta los resultados de un proyecto de investigación, cuyo propósito fue indagar cómo perciben los profesores estos cambios, cuáles son los problemas que identifican y qué tensiones se generan en sus identidades profesionales. A tal fin se consideraron los procesos de inclusión de nuevos adolescentes y la integración de TICs en la secundaria. Asimismo, se analizan los desafíos para la formación y desarrollo profesional de los docentes.     La investigación se llevó a cabo desde una perspectiva sociocrítica; con métodos de recolección de información en extensión y la aplicación de un cuestionario semi-estructurado. Las preguntas abiertas fueron sistematizadas con el software Atlas-Ti para análisis de datos cualitativos.","palabras_clave":"DOCENTE DE SECUNDARIA|FORMACIÓN DOCENTE|FORMACIÓN PROFESIONAL|DEMOCRATIZACIÓN DE LA EDUCACIÓN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":26156,"idioma_id":5,"titulo":"Evaluación multicriterio de la expansión urbana, visión 2030. El caso Río Cuarto, Córdoba, Argentina. En Evaluación","resumen":"La tasa de conversión de las tierras rurales a urbanas será mayor que la tasa de crecimiento de la población urbana si se mantiene el patrón de urbanización actual. El objetivo de este trabajo es mostrar un modelo multicriterio para evaluar propuestas de expansión urbana (PEU) mediante una aplicación, en la ciudad de Río Cuarto, Córdoba Argentina. Cinco PEU fueron desarrolladas para el año 2030: PEU1-Tendencial,prognosis del patrón de urbanización; PEU2-Ecociudad, y tres PEU compactas localizadas al norte, oeste y sur de la ciudad. Los criterios de decisión son: la población, la pérdida de la renta agraria, la pérdida de servicios ecosistémicos, el costo de la infraestructura vial, el transporte de residuos sólidos domiciliarios, la extensión de redes de servicios públicos, y el esfuerzo político institucional (la distancia entre la situaciónactual y la visión futura). Un SIG e información inmediata disponible son usados para cuantificar los criterios y el método PROMETHEE es usado para evaluar las PEU. Se concluye que las PEU compactas (incluye ecociudad) tienen mejor performance económica, social, y ambiental que la PEU1 mientras que ésta eselegida solo en los casos que se reduzcan significativamente la cobertura de servicios públicos o el esfuerzo político institucional.","palabras_clave":"Planificación|urbanización|conflictos|rural"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":26270,"idioma_id":5,"titulo":"Caracterización del comportamiento reproductivo de machos cabríos mestizos (Criollo x Anglo Nubian) en la región sur de Córdoba, Argentina. I. Desencadenamiento de la pubertad.","resumen":"El objetivo de este trabajo fue caracterizar en la región centro sur de Córdoba, Argentina; el proceso de madurez sexual en machos cabríos mestizos Criollos locales x Anglo Nubian. Se trabajó con 17 machos púberes, nacidos en otoño en un rodeo de la zona. Se los mantuvo a corral, bajo condiciones ambientales naturales. Fueron alimentados con maíz molido y heno de alfalfa, según los requerimientos para dicha categoría y agua ad-libitum. Mensualmente se registraron peso vivo, circunsferencia escrotal, tono testicular y niveles séricos de testosterona. Dos veces por semana se colectó semen con vagina artificial y se evaluaron los eyaculados para determinar madurez sexual según el siguiente criterio: que el semen contuviera en promedio un volumen de 0,4 ml y una concentración de 2000 x 106 espermatozoides\/ml con 65 % de motilidad rectilínea progresiva y 75 % de morfología normal, como mínimo. Estadísticamente se realizaron análisis exploratorios de los datos y correlaciones mediante el test de Pearson. Se concluye que en la región sur de Córdoba, Argentina, la pubertad en machos cabríos mestizos Criollo local x Anglo Nubian se inicia en promedio a los 340,82 ± 5,76 días (11 meses) de vida con 34,58 ± 3,10 Kg de peso vivo, 27,04 ± 4,03 cm de circunferencia escrotal, 2,44 ± 0,48 de tono testicular y 2,19 ± 0,27 ng\/ml de testosterona y que la edad a la madurez sexual se correlaciona positivamente con el peso vivo, la circunferencia escrotal, el tono testicular y los niveles séricos de testosterona.","palabras_clave":"PRODUCCIÓN CAPRINA|RAZA CRIOLLA X ANGLO NUBIAN|LATITUD|PUBERTAD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":26271,"idioma_id":5,"titulo":"Re-sincronización de celos utilizando progestágenos y benzoato de estradiol, en vacas de carne (Bos Taurus) con cría al pie, manejadas en sistemas pastoriles de regiones áridas","resumen":"El objetivo de este trabajo fue comprobar si la resincronización conprogestágenos y benzoato de estradiol (BE) aumenta el porcentaje de preñez(PP) y la concentración de celos en vacas Aberdeen Angus en sistemaspastoriles. 75 vacas multíparas, con cría al pie, fueron sincronizadas para laprimera inseminación a tiempo fijo (IATF) colocando un progestágenointravaginal (DIV) y 2 mg de BE al día 0. El día 8 se retiró el DIV y se aplicóprostaglandina F2&#945; y 1 mg de BE en el día 9. La IATF se realizó a las 54 hrs deretirado el DIV. Para el segundo servicio, las vacas fueron dividas en 2 grupos.El G1 (n= 17) se resincronizó a los 13 días post IATF re-utilizando los DIV más1 mg de BE. A la semana se retiró el DIV y se aplicó 0,5 mg de BE. La IA acelo detectado comenzó a las 24 hrs. El G2 (n=17) no recibió ningúntratamiento, y la IA a celo detectado fue entre los 18 a 26 días post IATF. El PPfue analizado por regresión logística y la distribución de celos por el método deKaplan-Meier. No hubo diferencias en el PP entre ambos grupos para lasegunda IA (G1 = 76.5% y G2 = 82.3%). No obstante, los celos fueronsignificativamente más concentrados en el G1 (p<0.001). La resincronizaciónde celos aplicando CIDR + BE incrementa la sincronía de retorno al celo devacas vacías a la primera IATF sin afectar la preñez al segundo servicio.","palabras_clave":"PRODUCCIÓN BOVINA|SINCRONIZACIÓN DE CELOS|RESINCRONIZACIÓN|INSEMINACIÓN ARTIFICIAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":26297,"idioma_id":4,"titulo":"New variants of Verticillium dahliae causing sunflower leaf mottle and wilt in Argentina-MP-","resumen":"Thesunflower leaf mottle and wilt caused by Verticillium dahlie Kleb. is a major disease of the crop. The populations of V.dahliae are variable and physiological racesof the pathogen have been reported in lettuce, pepper, spinach, sunflower andtomato. The classification of V. dahliae isolates based on their pathogenicity in differentialsunflower genotypes to determine races of the pathogen gives useful informationfor growers and breeding programmes. Two new V.dahliae races causing sunflower leaf mottle andwilt in sunflower hybrids previously known as resistant wererecognized. The sunflower inbred lines ADV29 and ADV53 allowed to differentiatespecific pathogenicity patterns. One isolate that affected both genotypes was postulatedas race VArg3, and another group that did not cause disease on either genotypewas described as race VArg4. Sunflower genotypes showing inverse differential reactionsto races VArg3 and VArg4 were not found. However, the observed pathogenicitypatterns could be considered a phenotypic marker useful to identify the V.dahliae races VArg3 and VArg4 in monitoring studies. Thecurrent presence of four races of V.dahliae affecting sunflower in Argentina is discussed","palabras_clave":"genotypes|breeding|differential lines|resistance"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":26368,"idioma_id":5,"titulo":"CONFLICTOS DERIVADOS DE LA EROSIÓN COSTERA: RESPONSABILIDADES ESTATALES. CAMET NORTE, PARTIDO DE MAR CHIQUITA, PROVINCIA DE BUENOS AIRES, ARGENTINA","resumen":"La evidencia geológica indica la existencia de un severo proceso erosivo en la zona costera de Camet Norte Partido de Mar Chiquita, provincia de Buenos Aires, producidos, tanto por la acción natural del mar, como por acciones antrópicas. (SCHNACK et al. 1983:130 BUNICONTRO et al. 2012:21)El presente trabajo pretende determinar la participación y la responsabilidad del Estado por su accionar en las respuestas que le dio a la problemática en la zona en estudio. Para ello, se evalúa la situación ambiental de la zona y se establecen los diferentes factores dominantes y legales que determinaron la problemática actual del área, desarrollaremos los argumentos jurídicos que nos permiten dimensionar la responsabilidad del Estado en dicho conflicto, a través de un marco teórico y los comentarios de una causa judicial suscitada como consecuencia de esta problemática.","palabras_clave":"EROSIÓN COSTERA|PLANIFICACIÓN COSTERA|GESTIÓN INTEGRAL COSTERA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":26406,"idioma_id":5,"titulo":"Devenires de la autoridad en la escuela","resumen":"El presente trabajo da cuenta de una experiencia de intervención en una escuela secundaria de la ciudad de Villa Mercedes, San Luís,  a través de la realización de un  taller de reflexión sobre la autoridad docente. El taller se desarrolló con docentes de 6º año con el objetivo de crear condiciones para pensar colectivamente las prácticas profesionales en relación a la autoridad, valiéndonos del espacio grupal como espacio intermediario.El taller permitió recuperar la dimensión subjetiva a partir de la indagación en una instancia individual y colectiva que permitió pensar y pensarse en el ?entre? de un dispositivo grupal, que posibilitó nominar el malestar, y asimismo auguró la posibilidad de construir nuevas significaciones en relación al tema de la autoridad, desarrollando un pensamiento crítico, autonomía de opinión y de criterio, como así también la fuerza creadora de esos miembros del grupo para abrirse a la creatividad  y el devenir.","palabras_clave":"AUTORIDAD|TALLER DE REFLEXION |ESCUELA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":26477,"idioma_id":4,"titulo":"Antisnake venom activities of Aloysia citriodora Palau: New applications for a known aromatic plant","resumen":"Traditional medicine in Corrientes Province (Argentina) uses preparations from herbs as one form of medication for the treatment of bites from venomous animals in the form of infusions and cataplasms. We evaluated the effect of essential oils and extracts from aerial parts of A. citriodora against Bothrops diporus venom, yarará chica, in order to prove the traditional antisnake venom properties suggested for this species. Besides, a seasonal and geographical evaluation of the chemical composition of the essential oil was performed in order to assess about its chemical stability. We also demonstrated that A. citriodora possesses, in vitro, antisnake venom activity against B. diporus venom and that essential oil components could be considered as a part of its active constituents. They are the most likely responsible for the plant?s potential therapeutic benefits since they attenuate the proteolytic, coagulant and indirect hemolytic activities of B. diporus venom.","palabras_clave":"ACTIVIDAD ALEXITÉRICA|FITOQUÍMICA|ETNOMEDICINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":28002,"idioma_id":5,"titulo":"'¿Son a priori los modelos explicativos de la selección natural?'","resumen":"El estatusepistémico de la Selección Natural ha intrigado a biólogos y filósofos porigual, desde sus inicios hasta nuestros días. Un ejemplo contemporáneoprominente es Elliot Sober, quien afirma que la Selección Natural y otrasteorías biológicas ?yquizás económicas?son peculiares por incluir modelos explicativos\/condicionales que son a priorien un sentido en el que los modelos explicativos\/condicionales de la MecánicaClásica y la mayoría de las demás teorías estándar no lo son.En este artículo, analizando lo que creemos ser las cuatro posiblesinterpretaciones de la tesis de Sober, argumentamos que, dejando de lado laspreferencias terminológicas, los posibles sentidos en los que los modelosexplicativos de la Selección Natural pueden contar, o incluyen elementos quepueden contar, como a priori, también se aplican a la Mecánica Clásica y aotras teorías estándar, altamente unificadas.","palabras_clave":"SELECCIÓN NATURAL|SOBER|MODELOS EXPLICATIVOS A PRIORI"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":28272,"idioma_id":4,"titulo":"Egg parasitoid complex of the corn leafhopper, Dalbulus maidis (Hemiptera: Cicadellidae), in northwestern Argentina","resumen":"The corn leafhopper, Dalbulus maidis (DeLong), is the most important leafhopper pest of maize, Zea mays, in the Americas. A survey of the diversity of its egg parasitoids was carried out in northwestern Argentina. During summer from 2004 to 2007 the samples were collected, using sentinel eggs of D. maidis on corn leaves, exposed in 48 cornfields. Sixteen species belonging to four families of Chalcidoidea (Hymenoptera) were identified. Among the parasitoid groups, Trichogrammatidae was the most represented family with eight species, followed by Mymaridae with six species. The mymarid Anagrus incarnatus Haliday and the trichogrammatid Pseudoligosita longifrangiata (Viggiani) were the most abundant and frequent parasitoids. The mean percentage of parasitism of D. maidis eggs was 16.4% varied greatly among the sites, ranging from 0 to 56.7%; generally, it was higher in Yungas and lower in Monte province sites. The species richness was higher in the localities within the Yungas, with 13 parasitoid species, of which two species were dominant comprising 83.6% of the collected individuals. Monte was the province that showed the highest diversity index (H´= 1.62). In addition, we present information on the distribution, known host associations of each parasitoid species and an identification key to all species of egg parasitoids of D. maidis in Argentina.","palabras_clave":"Dalbulus maidis|corn leafhopper|Egg parasitoids|Argentina"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":28428,"idioma_id":5,"titulo":"'Los gestos fundacionales de la patria en la poesía rioplatense de la independencia'","resumen":"      Este  artículo estudia las colecciones de poesías patrióticas editadas en Buenos  Aires y Montevideo, durante las décadas de 1820 y 1830: La lira argentina (1824) y El  parnaso oriental (1835-1837). El objetivo es realizar una presentación de  las mismas, a partir de categorías teóricas propuestas por Raymond Williams,  que nos permitirán evaluar la diversidad discursiva, donde conviven sustratos  culturales de la colonia con nuevas tendencias importantes a futuro. Tras esta  nueva sistematización del corpus, proponemos un análisis de los usos  conceptuales de 'patria', restrictivos y funcionales a los intereses de las  elites criollas urbanas, quienes imponen una acepción política del término,  mediante un aprovechamiento de las potencialidades de articulación de los  imaginarios sociales que la literatura detenta.  ","palabras_clave":"LITERATURA ARGENTINA|POESÍA DE LA INDEPENDENCIA|NACIONALISMO|IMAGINARIOS SOCIALES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":28996,"idioma_id":4,"titulo":"Perspectives on social innovation from the south: power, asymmetries and the role of the State","resumen":"Social innovation (SI) can offer alternative forms of organization and novel solutions to complex problems faced by contemporary societies. As the State is increasingly under pressure from mounting societal challenges, it is assumed that SI can help to provide bottom up solutions in ways that can create transformative change. However, the relation between bottom up initiatives and the State can be difficult and sometimes contradictory.  Even more, assumptions about the diminishing powers of the State can be misleading and overstress the role of SI. Based on the study of the recent South American experience, in this paper we depart from this assumption seeking to understand what could be the role of public policies as initiators or supporter of SI.  By adopting a multi-level perspective (MLP), this paper will analyze processes of linkage and direct intervention of public policies with SI in Argentina and Brazil. We will analyze two top-down initiatives promoted by public policies that ultimately fostered SI in Argentina: the food self-production ?Pro-Huerta? program and the policies of the National Technology and Social Innovation Program. And one complemented case-study of a bottom up SI in Brazil - the One Million Cisterns- which was later inserted into public policies in Brazil.Together, these cases will allow us to understand the potentialities and limitations of SI and the kind of relations they established with public policies. In particular, we will consider how public policies can foster and support SI but also what could be the broader role of the State regarding long term asymmetries of power that can affect the development of SI. Although we recognize differences between Latin American countries with dual economies and deeper social and economic challenges to those of developed countries, we hope to provide some insights on the importance of the role of State as catalyzer of systemic change in certain context, while at the same time reinforcing societal constraints in others.","palabras_clave":"Social Innovation|Public Policies|State|Empowerment"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":29343,"idioma_id":5,"titulo":"Enfoques de aprendizaje en estudiantes universitarios en el Area de Salud Pública","resumen":"Introducción: los enfoques de aprendizaje aluden a la predisposiciónpara aprender en diferentes situaciones académicas. Objetivo: se analizanestos enfoques (tipos profundo y superficial) en estudiantesuniversitarios de Buenos Aires. Metodología: participaron 397 estudiantesde diferentes facultades (Exactas y Naturales, Psicología, Ingeniería,Derecho, Medicina) entre 18 y 36 años. Resultados: los resultadosmostraron diferencias según sexo en los enfoques profundo ysuperficial, favorables en el primer caso a las mujeres, y en el segundoa los varones. Con respecto a la variable Facultad, se registraron variasdiferencias, destacándose los estudiantes de Exactas y Naturales en elenfoque profundo, y los de Ingeniería en el superficial, en relacióncon el resto de las facultades. Posteriormente, se analizó la relaciónentre enfoques y rendimiento académico en cada facultad, verificándoseasociaciones estadísticamente significativas para los grupos deIngeniería y Medicina. Conclusiones: los resultados muestran el efectoque la variable facultad ejerce sobre los enfoques de aprendizaje, dandocuenta de la relevancia que los tipos de enseñanza adquieren en laconfiguración de aquellos. Las correlaciones observadas con el rendimientoacadémico resaltan la importancia del tipo de enfoque paraciertas carreras. Se espera que la información presentada contribuya ala planificación de actividades tendientes a mejorar el aprendizaje decontenidos por parte del estudiantado.","palabras_clave":"enfoque aprendizaje|intensidad de enfoque|salud|universitarios"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":29356,"idioma_id":4,"titulo":"Ecological and evolutionary impacts of increasing climatic variability","resumen":"While average temperature is likely to increase in most locations on Earth, many places will simultaneously experience higher variability in temperature, precipitation, and other climate variables. Although ecologists and evolutionary biologists widely recognize the potential impacts of changes in average climatic conditions, relatively little attention has been paid to the potential impacts of changes in climatic variability and extremes. We review the evidence on the impacts of increased climatic variability and extremes on physiological, ecological and evolutionary processes at multiple levels of biological organization, from individuals to populations and communities. Our review indicates that climatic variability can have profound influences on biological processes at multiple scales of organization. Responses to increased climatic variability and extremes are likely to be complex and cannot always be generalized, although our conceptual and methodological toolboxes allow us to make informed predictions about the likely consequences of such climatic changes. We conclude that climatic variability represents an important component of climate that deserves further attention.","palabras_clave":"climate change|community structure|demography|fitness|geographic range limits|phenological mismatches|phenotypic plasticity|physiological traits|population dynamics|species interactions"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":29965,"idioma_id":5,"titulo":"Localización y tipología de hábitat como dimensiones de análisis de la política habitacional en la Ciudad de Buenos Aires a partir del año 2003","resumen":"Desde  2003,  Argentina  ingresó  en  un  proceso  de  progresiva  recuperación  económica,  que impactó positivamente sobre los salarios y los niveles de empleo. En la ciudad de Buenos Aires, la  construcción  civil  estuvo  entre  las  actividades más  dinámicas  y  la  edificación  residencial experimentó  un  crecimiento  sin  precedentes.  Sin  embargo,  la  situación  habitacional  de  los hogares  no  mejoró.  Este  artículo  describe  el  diseño  e  implementación  de  las  políticas habitacionales desde 2003, a partir del análisis de las intervenciones en la Ciudad de Buenos Aires en diferentes barrios populares: la Villa 31, la Villa 19, el asentamiento Rodrigo Bueno y los conjuntos habitacionales en Lugano y en La Boca. Para ello, se caracteriza la dinámica demográfica  y  la  evolución  del  déficit  habitacional  en  la  ciudad,  se  analizan  las  políticas desplegadas  sobre  diferentes  tipologías  de  hábitat popular  y  se  discute  su  impacto  en  el territorio.","palabras_clave":"Política habitacional|Política urbana|Habitat|hábitat social"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":30277,"idioma_id":5,"titulo":"Guardia Nacional de Buenos Aires en el período del Presidente Derqui","resumen":"La Presidencia de Sarmiento generó para la Guardia Nacional de Buenos Aires un Reconocimiento por su actividad en la Guerra contra el Paraguay, unan reorganización de misiones y les dió un mandato para complementar al Ejército de Línea en sus actividades de ampliar las fronteras.-","palabras_clave":"Constitución |ruptura|pavón |reconocimiento"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":30788,"idioma_id":6,"titulo":"La révolution athénienne. Penser l'événement démocratique","resumen":"Indexación: www.scopus.com - www.aeres-evaluation.com - dialnet.unirioja.es - dbh.nsd.uib.no\/publiseringskanaler\/erihplus - Resumen: En este artículo analizo la democracia ateniense a partir de la relación entre las prácticas políticas y las prácticas discursivas, identificando el acontecimiento democrático con las reformas de Efialtes y examinando esta mutación en su singularidad histórica así como según la manera en que es asimilada a través de las formas de pensar la política. Desde el punto de vista teórico, se trata de estudiar la aparición y la configuración de un sujeto político. La situación ateniense presente elementos singulares al respecto: durante siglo V a.C. los ciudadanos han asumido plenamente que la comunidad tenía que actuar sin ninguna restricción; como reunión del cuerpo político, la asamblea se convirtió entonces en el poder principal; la realización de la soberanía efectiva del dêmos implicó la libertad y la igualdad de todos los atenienses para participar en las decisiones de la colectividad. La conquista por el pueblo de esta capacidad suprema constituye, pues, el punto de partida para pensar el acontecimiento democrático y el sujeto político. En este sentido, la tragedia y la historia son, en mi opinión, dos discursos que pueden ser considerados como diferentes modos de pensamiento que trazan un balance de la aparición de la democracia ateniense. Se trata sobre todo de demostrar que estos discursos organizan un 'pensamiento en interioridad' con respecto a las prácticas democráticas, es decir que constituyen recursos para pensar activamente el acontecimiento democrático aquí designado como 'revolución ateniense' así como el impacto real de la experiencia política inédita desplegada por el dêmos ateniense.","palabras_clave":"Atenas|Democracia|Revolución|Efialtes"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":30842,"idioma_id":5,"titulo":"Desafíos para la educación secundaria","resumen":"ResumenLa presenteexposición parte de considerar que los mandatos fundacionales de la educaciónsecundaria argentina están en crisis&nbsp; yque por lo tanto&nbsp; nuevos desafíos seestablecen en cuanto a sus destinatarios, su función, el tipo de formación quese recibe como así también respecto de sus formatos y estructurascurriculares.&nbsp; Aquí se analizan&nbsp; cada uno de los aspectos mencionados y seenfatiza acerca de las dificultades vinculadas al acceso masivo a la educación.Si bien se analizan un conjunto de factores al respecto,&nbsp; se hace especial&nbsp; hincapié en los formatos escolares y alas&nbsp; estructuras curriculares.&nbsp; Asimismo, se destaca el rol protagónico quetiene la universidad en general y las instituciones de formación docente enparticular respecto de los procesos de formación de los profesores.&nbsp; Parafinalizar&nbsp; se exponen un conjunto deideas tales como: experiencias educativasalternativas, procesos de construcción curricular, saberes del docente,contenidos curriculares comunes, las cuales son consideradas potentes paragenerar cambios en los procesos curriculares y en las&nbsp; prácticas de enseñanza. Quedanplanteados&nbsp; desafíos para la educación delas nuevas generaciones en la época actual.&nbsp;&nbsp;","palabras_clave":"EDUCACION SECUNDARIA |ESTRUCTURAS CURRICULARES |FORMACION DOCENTE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":31166,"idioma_id":5,"titulo":"Angustia y acedia como patología en el monacato medieval. Manifestaciones y recursos curativos","resumen":"Las patologías espirituales y psíquicas propias de los ámbitos monásticos medievales poseían una sintomatología común que se manifiestaba en la angustia frente a la propia existencia y que conoció como acedia. La respuesta terapéutica de los monjes medievales frente a esta situación pasa, entre otros, a través de ciertas variantes litúrgicas, entendida ésta como representación terapéutica y como palabra curadora, herederas ambas de la curatio verbi propia de los monjes del desierto egipcio. Se trata, en definitiva, de la capacidad performativa de liturgia. En este trabajo me propongo presentar los elementos más significativos de la acedia dentro del monacato cristiano y analizar tres textos litúrgicos como instancia terapéutica de esta afección.","palabras_clave":"ANGUSTIA|ACEDIA|LITURGIA|EVAGRIO PONTICO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":31180,"idioma_id":4,"titulo":"Latin American 'Free Trade Unionism' and the Cold War - An Analysis Based on Educational Policies","resumen":"The political education of workers and their leaders was viewed as a strategic concern in the Cold War period?s bipolar world. This article discusses how this issue was dealt with by Latin American reformist trade unions grouped together in the Inter-American Regional Organization of Workers (ORIT, for its Spanish acronym), analyzing the educational policies promoted by its Inter-American Institute for Labor Studies (IIES), focusing specifically on its educational program for trade union instructors. We argue that the nature of the education provided changed, shifting from a rationale based on explicit ideological confrontation to a more focalized technical type of training. We claim that this shift started in the early 1960s, when the Alliance for Progress was launched.","palabras_clave":"WORKERS' EDUCATION|INTER-AMERICAN REGIONAL ORGANIZATION OF WORKERS (ORIT)|LATIN AMERICA|COLD WAR"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":31600,"idioma_id":5,"titulo":"La utilización de lebrillos de cerámica popular como pilas benditeras y bautismales en iglesias coloniales hispanoamericanas","resumen":"Se ha identificado que en diversas iglesias de América Latina existen pilas bautismales hechas con lebrillos de producción manual en España e Inglaterra. Si bien estaba reglada la forma y material en que debían hacerse la falta de recursos llevó a usar objetos que ofrecía el mercado a bajo costo.","palabras_clave":"PILAS BAUTISMALES|CERAMICA|SIGLO XVIII|ARQUITECTURA AMERICANA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":31894,"idioma_id":5,"titulo":"Combinación de hongos movilizadores y solubilizadores de P con rocas fosfóricas y materiales volcánicos (cenizas y pumicitas) para la promoción de crecimiento de plantas de Lechuga (Lactuca sativa L.) Combination of P-solubilizers and mobilizers fungi wit","resumen":"Abstract: Los hongos formadores de micorrizas arbusculares (HFMA)incrementan la toma de fosfatos solubles, mientras que los hongossolubilizadores de P (HSP) promueven la solubilización de complejosinsolubles de fosfato, beneficiando la nutrición de las plantas. Otraalternativa para mantener la productividad de los cultivos es lacombinación de minerales o rocas que aporten nutrientes entre otraspropiedades deseables. El objetivo de este trabajo fue combinar HFMA yHSP con materiales piroclásticos (cenizas y pumicitas) del Volcán Puyehuey rocas fosfóricas (RP) del Grupo Río Chico (Chubut)- en la elaboraciónde un sustrato para la producción en maceta de Lactuca sativa. Paraformular los sustratos se utilizó una mezcla de Terrafertil® : ceniza.Penicillium thomii fue el HSP y esporas de Rhizophagus intraradices(HFMA) (AEGIS® Irriga). Los tratamientos fueron: 1) Sustrato 2) Sustrato+ HFMA 3) Sustrato + HSP 4) Sustrato + HFMA + HSP 5) Sustrato: RP 6)Sustrato: RP + HFMA 7) Sustrato: RP + HSP y 8) Sustrato: RP + HFMA + HSP.Se efectuaron 3 repeticiones por tratamiento. Todos los parámetrosevaluados: contenidos de P total y asimilable en sustrato, P en tejido ybiomasa seca vegetal fueron significativamente mayores en las plantas quecrecieron en el sustrato con RP, HPS y HFMA. Este trabajo confirma que lacombinación HSP\/HFMA con cenizas volcánicas del Puyehue y las RP delGrupo Río Chico formuladas con un sustrato comercial promueven elcrecimiento de L. sativa, incrementando de este modo el valor agregado degeomateriales de origen nacional.","palabras_clave":"Hongos solubilizadores de P|hongos movilizadores de P|roca fosfórica|cenizas volcánicas"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":31914,"idioma_id":4,"titulo":"Carnivore occurrence: do interview-based surveys produce unreliable results?","resumen":"Interviews with local people have been widely used by biologists because they are particularly suitable and cost-efficiently to approach certain topics in wildlife ecology and conservation. However, doubts still exist on the validity and quality of information gathered through them, especially in the case of studies targeting cryptic or elusive species, such as carnivores. In this paper we assessed the reliability of interviews (n=155) to detect the presence of three species of carnivores with different characteristics, by comparing interviews results with those obtained through camera trapping surveys (52 sites) in central Argentina. The degree of concordance between methods was low for the Geoffroy?s cat (Leopardus geoffroyi) and especially the puma (Puma concolor). However, Geoffroy?s cats were detected more frequently by camera traps than interviews, whereas the opposite was true for pumas. For the Pampas fox (Pseudalopex gymnocercus), a less elusive species, we observed a high degree of concordance and a similar probability of occurrence between methods. Our results indicate that data obtained by interviewing local inhabitants must be used with caution because locals provided information of presence that may be inaccurate and biased.","palabras_clave":"ARGENTINA|CAMERA TRAPPING|GEOFFROY'S CAT|PAMPAS FOX|PUMA|QUESTIONNAIRES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":32089,"idioma_id":4,"titulo":"In vitro antifungal\/fungistatic activity of manganese phosphite against soybean soil-borne pathogens","resumen":"Resumen. Las pudriciones de raíz y tallo (PRYT) en el cultivo de soja causadas por patógenos habitantes del suelo son enfermedades comúnmente encontradas en campos de soja y son una de las causas más importantes de pérdidas económicas. La sensibilidad micelial de Fusarium virguliforme, Fusarium tucumaniae, Sclerotinia sclerotiorum y Macrophomina phaseolina fue evaluada en medio de cultivo agar papa glucosa (25 mL) suplementado con diferentes concentraciones (µg mL-1) de fosfito de manganeso (PhiMn) diluido en agua (0; 25; 37.5; 50; 100; 200; 300; 400; 500; 800 y 1000). La sensibilidad del crecimiento micelial fue analizada usando análisis de regresión lineal logarítmico. La concentración de PhiMn necesaria para inhibir el 50% del crecimiento micelial (CI50) fue calculada. Los valores de CI50 fueron desde 105 µg mL-1 (Fusarium spp.) hasta 409 µg mL-1 (M. phaseolina). La formación de esclerocios fue completamente inhibida a 500 µg mL-1. Los resultados del presente estudio representan el primer reporte de la acción fungicida\/fungistática in vitro del Phi contra los hongos agentes causales de PRYT en el cultivo de soja.","palabras_clave":"GLICINE MAX|FUSARIUM VIRGULIFORME|FUSARIUM TUCUMANIAE|MACROPHOMINA PHASEOLINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":32132,"idioma_id":5,"titulo":"Las políticas territoriales y la construcción de la emergencia. La región andina de la provincia de Río Negro","resumen":"En este artículo se explora la historia normativa relacionada a las emergencias en la Provincia de Río Negro, Argentina. Este análisis busca indagar en el carácter político detrás del reconocimiento de una situación como emergencia o catástrofe. Para ello se profundizará en el modo en que se han reconocido las emergencias en un área particular, la zona andina, buscando cruzar las memorias locales sobre situaciones vividas como catástrofes por la propia población, respecto de la trama legislativa que acompaña o no este reconocimiento.Desde esta caracterización se buscará avanzar en la complejidad del reconocimiento de un evento como emergencia, y en la pluralidad de actores involucrados en ese proceso. Como síntesis del estudio se expondrá el detalle histórico sobre el tipo de legislaciones que fueron sancionadas en este sentido, interpelando desde allí los límites y las capacidades para dar cuenta del impacto social de una emergencia con las herramientas estatales.","palabras_clave":"Emergencia|Política|Provincia de Río Negro|Zona Andina"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":32145,"idioma_id":5,"titulo":"LINAJES MITOCONDRIALES EN MUESTRAS DE ESQUINA DE HUAJRA (JUJUY, ARGENTINA). APORTES AL ESTUDIO DE LA OCUPACIÓN INCAICA EN LA REGIÓN Y LA PROCEDENCIA DE SUS HABITANTES","resumen":"El sitio arqueológico Esquina de Huajra (centro-sur de la Quebrada de Humahuaca)corresponde a una instalación ubicada cronológicamente en la Fase Inca (ca. 500-420 AP) y la tradicionalmente asignada en el noroeste argentino como Hispano Indígena o de primeros contactos con el español (ca. 420-320 AP). Enmarcado en la política económica incaica, habría sido clave en la explotación y Distribución de bienes procedentes de las Yungas Orientales.Además, su cultura material sugiere importantes redes de interacción con las tierras altas,planteando interrogantes sobre la conformación poblacional de sus habitantes.En este trabajo se analizan los linajes maternos de individuos de Esquina de Huajra en comparación con otros sitios del centro-sur andino para evaluar su posible origen foráneo,considerando que el reasentamiento de poblaciones fue una práctica imperial recurrente.El ADN fue extraído de piezas dentales de 6 individuos. Se secuenció la Región Hipervariable I del ADN mitocondrial en cuatro individuos hallándose dos A2 y dos C1. La ausencia de B2 discrepa con lo descripto para gran parte de los sitios andinos, donde este haplogrupo es mayoritario. Dos de los cuatro haplotipos se comparten únicamente con otrossitios de la Quebrada de Humahuaca del Período de Desarrollos Regionales (Los Amarillos y San José); pero una variante nodal C1 fue reportada tanto en Juella como en sitios peruanos preincaicos e incaicos. Estos resultados representan un primer aporte al estudio genético de los habitantes de Esquina de Huajra y una evidencia más de los complejos procesos poblacionales en la región andina.","palabras_clave":"ADN ANTIGUO|HAPLOTIPOS MITOCONDRIALES|QUEBRADA DE HUMAHUACA|PERIODO INCAICO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":32512,"idioma_id":5,"titulo":"Variabilidad de la precipitación y su relación con los rendimientos agrícolas en una región semiárida de la llanura pampeana (Argentina)","resumen":"El objetivo de este estudio fue analizar la alternancia de períodos secos, húmedos y normales durante los años 1970-2012 en una región semiárida de la llanura pampeana argentina. La evolución de los rendimientos de un cultivo de secano (trigo) se analizó como indicador de dicha alternancia, durante el período 2000-2012. Se utilizó el Índice Estandarizado de Precipitación y Evapotranspiración (en inglés SPEI) y se analizó la superficie sembrada, cosechada y los rendimientos del cultivo de trigo. Los períodos normales según el SPEI fueron los más frecuentes en el área deestudio mientras que hubo una desigual proporción en la ocurrencia de eventos secos y húmedos. El año 2001 fue húmedo y los años 2008 y 2009 fueron secos. Durante estos últimos, disminuyeron los rendimientos y la extensión de la superficie cosechada de trigo, mostrándose como indicadores de la alternancia de períodos secos y húmedos.","palabras_clave":"Variabilidad de la precipitación|región semiárida|Índice Estandarizado de Precipitación y Evapotranspiración|cultivo de trigo"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":32515,"idioma_id":4,"titulo":"Laicidad and religious diversity: themes in the debates on the regulation of religion in Latin America","resumen":"This article serves as an introduction to the current volume by considering two central analytic themes that run through it: a) laicidad as a political limit on religion, and b) diversity in the forms of religious identification. While these central themes do not necessarily exhaustively reflect the current state of the debates on religion and politics in Latin America, they do represent two ways in which these debates have often been thought of in the region. They are approaches that, in addition to serving as a framework for the works contained in this volume, reflect a great part of the theoretical, analytical, and empirical reflections from Latin America.","palabras_clave":"LAICIDAD|RELIGION AND POLITICS|SECULARIZATION|LATIN AMERICA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":32547,"idioma_id":5,"titulo":"Isotopos estables, movilidad y camelidos en sociedades agropastoriles tempranas de la Puna Meridional Argentina","resumen":"En este trabajo se explora el manejo y la adquisición de camélidos domésticos y silvestres en las estrategias económicas y de movilidad de los grupos agropastoriles de Antofagasta de la Sierra (Catamarca, Puna Meridional Argentina) durante el Período Formativo, entre ca. 3000 y 1000 años AP. Para ello presentamos 25 valores de &#948;13C generados a partir de colágeno obtenido de restos óseos de camélidos recuperados en el sitio Casa Chávez Montículos. Dichos valores son discutidos en relación con los datos isotópicos de camélidos actuales del área de estudio. Los resultados alcanzados permiten sostener la hipótesis de la existencia de un patrón logístico de caza territorialmentegeneralizado a lo largo de todo el lapso cronológico considerado, como así también de un cambio en las estrategias de manejo del espacio y de los recursos de rebaño entre los momentos iniciales y tardíos del Formativo. De esta manera, mientras que durante el Formativo temprano la principal estrategia de pastoreo habría consistido en la explotación de las pasturas naturales presentes en los diferentes sectores microambientales del área, con énfasis en los pajonales de altura, hacia los 1800 años AP se observarían los primeros indicios de una nueva estrategia. Esta última se caracterizaría por una reducción de la movilidad y la posible complementación de la dieta de los recursos domésticos mediantes forrajes suplementarios.","palabras_clave":"Isótopos estables| Movilidad|Puna Meridional Argentina|Pastores,"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":32579,"idioma_id":4,"titulo":"Climate change in the mountains: Insights from a study of Saxicolous lichen communities in relation to altitude and microsite","resumen":"The extent to which small shifts among local topographic microsites could mitigate the effects of larger-scale climate change in arctic?alpine systems including mountain top organisms is largely unknown. This study is among the &#64257;rst to evaluate the relative contribution of microsite and altitude as a proxy for climate change on saxicolous lichen communities. We registered 107 lichen species in 54 boulders ranging from 900 to 2700 m.a.s.l. and in a large array of microsites in central Argentina. Communities ordinated along NMS multivariate analysis axes 1, 2 and 3 presented a cumulative R2 of 80%. The three axes were explained by altitude with axis 1 only being explained by altitude. Axis 2 was also explained by slope and aspect whereas axis 3 was explained by the interaction of altitude with aspect indicating that aspect was important only at lower altitudes but not at the mountain top. Lichen cover and richness were similar throughout the altitudinal gradient. We interpret that under a climate warming scenario, lower altitude species occupying pole ward facing slopes will have to migrate upwards while at the mountain top?for most communities?there still is scope for microsite segregation to compensate climate change.","palabras_clave":"diversity|lichen cover|rock outcrops|succession"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":32806,"idioma_id":4,"titulo":"Pecked and polished materials from southern Patagonia: An experimental techno-functional approach.","resumen":"The archaeological contexts of different periods from Southern Patagonia (Chile and Argentina) frequently include materials showing evidence of pecking and polishing techniques. Functional analysis of these materials is essential in order to identify traces of manufacture and use, and therefore to help us understand the techno-economic organization of these hunter-gatherer societies.This paper presents the results of an experimental program on manufacture and use wear traces on pecked and polished artefacts. This analysis allowed us to recognize natural, taphonomic, and technological traces and to build a methodological framework for the analysis of archaeological artifacts. These results are relevant for the analysis of the archaeological record, since they imply that it will be possible to recognize these traces on tools made by polishing techniques that have subsequently been used with other types of materials.","palabras_clave":"Tierra del Fuego|Hunter-gatherers|Use wear traces|Microscopy|Microwear analysis"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":32847,"idioma_id":5,"titulo":"'Están revueltas todas las cosas'. Sintomatología del Dinero Transferido por el Estado Mexicano a los Mayas Yucatecos","resumen":"En este artículo analizo cómo el dinero de las transferencias monetarias condicionadas del programa Oportunidades afecta corporalmente a sus receptores, en un pueblo del Este del Estado deYucatán, México. Más que como un puro medio de comunicación de valores económicos, estas transferencias monetarias estatales son consideradas, en una primera instancia, en tanto que desórdenes en las vidas de sus beneficiarios. Apartir de la descripción de distintas ideologías semióticas describo las cualidades, afecciones y marcas indexicales que el dinero transferido va dejando en el cuerpo de sus administradores. Finalmente sugiero que estos casos contradicen puntualmente una de las idealizaciones occidentales del dinero: el mismo puede ser entendido como expresión perfecta de un valor (i.e. relación derelaciones) únicamente si se adscribe a cierta ideología semiótica del valor marginal.","palabras_clave":"Transferencia Monetaria|Dinero|Maya|Cuerpo"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":33093,"idioma_id":4,"titulo":"DYNAMIC DAYLIGHT SIMULATION VARIABILITY ACCORDING TO WEATHER FILE USE","resumen":"While the use of satellite weather files is a possibility in regions without terrestrial stations, it is necessary to consider their impact on daylight simulations. This paper aims to verify the variability of dynamic daylight simulation results according to the weather file used. This study compares the results of daylight simulations in learning spaces using different weather files (land-based station data - satellite data). This work is divided in three main stages: comparative analysis of climatic databases; comparative analysis of annual outside horizontal illuminance; analysis of dynamic daylight performance metrics. Annual calculated dynamic daylight metric indicates variations of up to 13% under the different weather files analyzed. This is a relevant topic since the accurate prediction of daylight levels for indoor environments guides daylighting design.","palabras_clave":"DAYLIGHTING|CLEAR SKY|DYNAMIC DAYLIGHT SIMULATION|WEATHER DATA FILES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":33170,"idioma_id":4,"titulo":"Di(ethylene glycol) methyl ether methacrylate (DEGMEMA)-derived gels align small organic molecules in methanol","resumen":"Residual dipolar couplings (RDCs) constitute an important NMR parameter for structural elucidation in all areas of chemistry. In this study, di(ethylene glycol) methyl ether methacrylate (DEGMEMA)-basedgelsare introduced as alignment media for the measurement of RDCs of small organic molecules in polar solvents such as methanol. The low viscosity of methanol permits the execution of J-scaled BIRD HSQC experimentsthat yield very sharp lines in anisotropic conditions. The gels have excellent mechanical properties, and their compression and expansion in the swollen state can be reversed and performed multiple times.  This process enables the easy loading and release of analytes. The excellent performance of these new aligning gels is demonstrated by analyzing the structure of the alkaloid retrorsine.","palabras_clave":"J-SCALED BIRD HSQC|RESIDUAL DIPOLAR COUPLINGS|DEGMEMA GELS|ALIGNMENT MEDIA|RETRORSINE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":33172,"idioma_id":4,"titulo":"Circumscription of the South American Moonwort Botrychium (Ophioglossaceae)","resumen":"The genus Botrychium (Ophioglossaceae) is comprised of about 30 widely distributed species. Because of their small size and few, yet variable, morphological characters, many questionable taxa have been described over the years. Since its description in 1906, B. dusenii has been treated as both a distinct species and variously divided into four taxa: B. lunaria var. dusenii, B. lunaria var. antarctica, B. ramosum var. patagonicum, and B. matricariifolium subsp. patagonica. The aim of this study is to evaluate the validity of these taxa using spore wall sculpture, spore size, allelic composition employing enzyme electrophoresis, and morphological characters. We conclude that only one species of Botrychium occurs in the study area and recognize this as B. dusenii, a species distinct from B. lunaria. Enzyme electrophoresis and spore size suggest that B. dusenii is an allotetraploid derived through hybridization between a diploid member of B. lunaria complex and a diploid member of the B. campestre complex. We provide information about habitat, distribution, and full exsiccate citations.","palabras_clave":"ALLOZYMES|BOTRYCHIUM|ENZYME ELECTROPHORESIS|FERN SPORES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":33236,"idioma_id":4,"titulo":"Violent death, publics problems and changes in Argentina","resumen":"Nota: es la versión impresa del artículo que había aparecido antes en forma digital en la misma revista, por lo cual se modifica el año.This article makes connections between violent deaths, public problems and changes seenin the past 30 years in Argentina. The authors argue that the ways in which people werekilled, the ways in which their dead bodies were handled and the ways in which the dead andtheir behaviours were described in terms of morality play a key role in determining socialreaction and the challenging of public authorities. It is suggested that shock and outragein the face of the violent death of a defenceless, innocent person trigger political, socialand cultural changes in highly complex ways. Where contemporaries tend to establishalmost immediate causal relationships, a retrospective analysis shows that the rupturesand continuities following each death result from a variety of temporal and causal chains.A death?s ability to pose public problems can help us think about democratic processesin Latin America, indicating that democracies in the region are judged in terms of theircapacity to solve the public problems embodied by deaths like those analysed here.","palabras_clave":"VIOLENT DEATH|PUBLICS PROBLEMS|POLITICAL CHANGES|ARGENTINE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":33297,"idioma_id":4,"titulo":"DNA content in species of Vernonia and Vernonanthura from South America: An approach to systematics and evolution of the vernonieae (asteraceae)","resumen":"There are relatively few studies of DNA content in the Vernonieae (Asteraceae) tribe. The first studies were realized in the Lessingianthus genus and determined the DNA content of 25 species. After DNA content, ploidy level and the total karyotype were compared in 6 Chrysolaena species. The aim of this study was to present, for the first time, the DNA content values of Vernonanthura and Vernonia and to thereby expand knowledge of the Vernonieae tribe. A total of 19 natural populations belonging to the genera Vernonanthura and Vernonia were studied for the first time. The results were compared with other Vernonieae genera and with other Asteraceae tribes. Our results found that Vernonieae have the smallest range of 1C value variation in Asteraceae. Furthermore, there were differences in the DNA content of Vernonia and Vernonanthura. These results show that low DNA content and herbaceous habit in Vernonia are characters derived from the higher DNA content and woody habit present in Vernonanthura. These results could indicate a hybrid origin of one species and allow the determination of both the ploidy and chromosome number of other taxa. The results observed in Vernonanthura species showed a highly significant correlation between 1C-value and latitude.","palabras_clave":"Asteraceae|evolution trends|genome size|systematic"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":33340,"idioma_id":5,"titulo":"La provincia fitogeográfica del monte, límites territoriales y su representación","resumen":"La definición de límites de cualquier unidad geográfica, en base a la fisiografía del paisaje, resulta útil al momento de desarrollar políticas y pautas de manejo ambiental. Distintos autores han divido la República Argentina en regiones de acuerdo a las características de su vegetación nativa. En Argentina, estas divisiones se conocen como Provincias Fitogeográficas o Ecorregiones. La Provincia Fitogeográfica del Monte constituye una de las ecorregiones más extensas del país y se caracteriza por ser una unidad donde los aspectos ambientales son complejos y difíciles de categorizar. En el presente trabajo se realiza una revisión de los límites de esta Provincia Fitogeográfica, conforme a los antecedentes bibliográficos y diferentes autores, tomando como criterio diferentes sistemas de clasificación en forma combinada y alternada. Los límites y características propuestos han sido corroborados a través de viajes y evaluaciones de algunas variables de suelo, topografía, vegetación y clima más relevantes in situ, realizados sobre dicha región por los autores del presente trabajo. Se considera que la definición de J. Morello del año 2012 puede ser la representación más consistente con la realidad del territorio, aunque se recomienda incluir como Distrito a la región de la Prepuna en el Monte Septentrional.","palabras_clave":"Monte|Límites"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":33563,"idioma_id":4,"titulo":"Assessment of physiological effects of sublethal Cadmium on Cyprinus carpio","resumen":"The effects of sublethal and short-term exposure to Cd were assessedwith the purpose of studying the energy metabolism parameters in youngCyprinus carpio under laboratory conditions. The fish were exposed to Cdsolutions (0.20 mg Cd. L?1) over a two-week term. The assayed concentrationwas environmentally realistic since it was frequently found in most highlypolluted peri-urban water bodies in Argentina. No mortality was recordedamong the animals during the experiments. The relationships betweenassimilation efficiency (U), oxygen consumption as a measure of specificmetabolic rate (SMR) and ammonium excretion (AE) were determined. Afterexposure to Cd, a significant correlation was found between SMR and AE.It was concluded that under the assayed conditions the metal caused alterationsin energy-related homeostasis of fish. Most of the responses may be interpretedas indicative of adaptations to compensate for increased energy requirementsdue to the physiological impairments caused by Cd","palabras_clave":"CYPRINUS CARPIO|CADMIUM|ASSIMILATION EFFICIENCY|OXYGEN COMSUMPTION|SPECIFIC METABOLIC RATE|AMMONIUM EXCRETION|SURFACE RESPONSE"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":33694,"idioma_id":5,"titulo":"Cuerpos, lenguajes y poéticas subjetivas. Aportes de la translingüística barthesiana para pensar la experiencia biográfica (y las derivas de la identidad) en clave cultural, educativa e histórica","resumen":"En el presente trabajo expondremos algunas nociones centrales de la semiología barthesiana relacionadas con la constitución (e imposibilidad) de la subjetividad, a partir de una lectura de la inscripción de intensidades simbólicas (biográficas y educativas) sobre el propio cuerpo. Es decir que intentaremos pensar una particular relación epistémica entre semiología, educación, subjetividad, saber y verdad. Realizamos esta articulación clave desde la perspectiva del Análisis Político del Discurso (que retoma la tradición de la lingüística saussureana a partir de los aportes del post-estructuralismo y de la deconstrucción, fundamentalmente), situándonos en sus lineamientos teóricos y metodológicos transdisciplinarios y en la crítica barthesiana al sistema de sentido de la racionalidad occidental.Creemos importante analizar los principales aportes conceptuales de Barthes (en el contexto del pensamiento semiológico francés post-estructural) sobre el abordaje de diferentes sistemas significantes indagados desde las luces y sombras del paradigma lingüístico, para intentar una cierta interrogación de diversas dimensiones psíquicas y sociales que configuran históricamente los discursos, la identidad y las lógicas simbólicas de la vida cultural y subjetiva (en lo que se ha denominado la 'translingüística barthesiana' y su crítica semiológica al 'sistema de clausura' logocéntrico).A tales fines, abordaremos en especial su momento teórico post-estructuralista, para vincular sus nociones 'fantasmadas' centrales en la configuración del sentido -tales como cuerpo, experiencia, texto plural, valor, significancia, diferencia, imaginario, punctum, semiografías, biografemas, rasgos, entre otras- con nociones centrales de la perspectiva teórica del Análisis Político de Discurso -tales como significante vacío y punto nodal, en Laclau y Mouffe; point de capiton, en Lacan y Zizek; différance y huella en Derrida-.Desde esta mirada transdisciplinaria que toma sus elementos analíticos fundamentalmente de la semiología postestructuralista, del psicoanálisis lacaniano y de la teoría política postmarxista -mediante un posicionamiento filosófico post fundacional- intentaremos pensar la constitución de la subjetividad en tanto experiencia educativa (o inscripción biográfica de saberes y des-conocimientos vitales), analizando cómo la propia historia del sujeto puede ser repensada y resignificada en relación con estos conceptos teóricos que no son sólo interpretaciones del mundo, sino, como lo sostiene Barthes, 'una historia implicada en el propio mundo vivido'.","palabras_clave":"LENGUAJES|SUBJETIVIDADES|IMAGINARIOS|BIOGRAFEMAS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":33738,"idioma_id":5,"titulo":"Juego de carta: la lucha por el poder en Leviatán y Behemoth de Thomas Hobbes","resumen":"Resumen: el artículo propone avanzar en una lectura de Hobbes en la que se identifique la persistencia de la lucha por el poder una vez celebrado el pacto y el modo en que esta afecta la puesta en escena del monopolio de los juicios que determinan los límites de la obediencia política. A tal fin se abordan dos de sus textos (Leviatán y Behemoth) para observar cómo se entremezclan los principios racionales con hipótesis sobre el funcionamiento histórico de la sociedad. Con ello se busca denotar el modo en que Hobbes constituye simbólicamente el orden sin desconocer, al mismo tiempo, que el cuerpo político del soberano, tal como lo describe, supone lidiar con la inmanencia del poder instituyente imposible de monopolizar. Así, Hobbes teme sus irrupciones, pero también reconoce la imposibilidad de su sacrificio último a través, por ejemplo, de una formulación de la soberanía fundada en el poder de facto del terror.","palabras_clave":"CUERPO POLÍTICO|LUCHA POR EL PODER|SOBERANÍA|RESISTENCIA|INMANENCIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":33742,"idioma_id":5,"titulo":"Estrategias de organización del sindicato Camioneros (1991-2011)","resumen":"En los últimos veinte años, la mayor visibilidad y protagonismo del sindicato de Camioneros en el desarrollo de las relaciones laborales de la Argentina, no sólo respondió a diversos factores del contexto socioeconómico que desde 2003 alentaron la acción sindical, sino también a su trayectoria y consolidación institucional. Analizar dicho protagonismo constituye el objetivo de este artículo, el cual buscará comprender cómo aquél actor construyó y fortaleció su capacidad de organización, entendida ésta como la habilidad para configurar una estructura interna capaz de afrontar los cambios del contexto político-económico en el que la organización se desenvuelve. El abordaje metodológico seleccionado es el estudio de caso, a partir del cual se procedió a la comparación diacrónica de dos procesos socio-históricos del sindicato, 1990-2002 y 2003-2011. Para ello se realizaron entrevistas en base a una muestra intencional multivocal que facilitó la interpretación de dichos procesos. Nuestro análisis muestra que a partir del 2003 no fueron sólo las oportunidades provistas por el contexto las que fortalecieron la capacidad de organización del sindicato de Camioneros, sino que resultó fundamental la habilidad de sus dirigentes para interpretar lo que sucedía. Así, sus acciones buscaron aprovechar las características y escenarios que presentaba cada período (y contexto) estudiado. El aporte del artículo se sitúa en el campo disciplinario de las relaciones laborales, utilizando las teorías de análisis estratégico que toman como elemento central el concepto de ?opciones estratégicas'. Bajo esta perspectiva teórica, el estudio de la capacidad de organización del sindicato Camioneros, permite no sólo reconstruir la dinámica de las relaciones laborales argentinas entre los años 1991-2011, sino que al mismo tiempo colabora con la profundización del análisis de la heterogeneidad sectorial que mostró el resurgimiento sindical en la Argentina durante dicho período.","palabras_clave":"ESTRATEGIA SINDICAL|CAPACIDAD DE ORGANIZACIÓN|SINDICATO CAMIONEROS|RECURSOS DE PODER SINDICAL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":34072,"idioma_id":5,"titulo":". Indicadores de conocimiento sobre biodiversidad aplicados a colecciones científicas: diagnosis de la colección Cicadellidae (Insecta: Hemiptera) del Museo de La Plata, Argentina.","resumen":"Se caracterizó la diversidad de la colección de Hemiptera Cicadellidae del Museo de La Plata utilizando los siguientes indicadores: 1) Identificación taxonómica, grado de resolución taxonómica de la colección, 2) Representatividad taxonómica y geográfica de los especímenes montados, 3) Porcentaje de asociaciones biológicas con plantas o parasitoides. Estos indicadores fueron comparados con los del Neotrópico y con la escala del Índice de Salud de Colecciones (escalas 6, 7 y 8). Se registraron 74 géneros, 119 especies y 2.796 ejemplares de Cicadellinae, Coelidiinae, Deltocephalinae, Idiocerinae, Ledrinae y Xestocephalinae para Argentina más 110 especímenes del extranjero. Para la identificación taxonómica, el material se agrupó en cuatro categorías: A- Tipo etiquetado, fichado, catalogado y publicado, B- Identificado a especie, etiquetado, fichado, con datos biológicos (escalas 6 y 7), C- Identificado a género, etiquetado, fichado y D- Identificado a Subfamilia, etiquetado, fichado (escala 8). Del grupo A se encontraron 166 especímenes, el grupo B representa el 94,95% de los ejemplares (2.655) (escalas 6 y 7), del grupo C el porcentaje fue de 2,18% (61 ejemplares) y del grupo D el 2,86% (80 ejemplares) (8). La representatividad taxonómica de la colección es del 40,9% a subfamilia respecto al Neotrópico. A nivel genérico, las mejor representadas fueron Xestocephalinae, Ledrinae (33,3%), Cicadellinae (18,7%) y Deltocephalinae (17,7%). A nivel específico Ledrinae (12%), Deltocephalinae (6,5%) y Cicadellinae (4,2%). Cicadellinae y Deltocephalinae representan el 96% de los ejemplares. La representatividad geográfica respecto a la Argentina fue alta 86,95 %; sólo el 12,53% de los ejemplares presentó plantas asociadas.","palabras_clave":"Auchenorrhyncha| Chicharritas| Colección Entomológica| Indicadores de biodiversidad"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":34168,"idioma_id":5,"titulo":"Politizar la economía política. Un diálogo epistémico con Nancy Fraser","resumen":"El presente trabajo revisa tesis centrales de Nancy Fraser que suscitan la hipótesis que afirma que los proyectos probables de país, de economía y de sociedad para la Argentina actual, tendrán un componente de cultura política de mayor significación que el imperante en países cercanos. La sospecha es que la razón práctico política recibe una carga normativa desbordante desde la experiencia y la historia. En este contexto se indagará la posibilidad de hacer converger la noción fraseriana de justicia social con una lectura democrática del concepto de lo político en Carl Schmitt. El propósito es volver sobre la urgencia de una nueva crítica de la economía política.","palabras_clave":"JUSTICIA|POLÍTICA|ECONOMÍA|DEMOCRACIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":34439,"idioma_id":4,"titulo":"Lost in Translation: Unknowable propositions in probabilistic frameworks","resumen":"Some propositions are structurally unknowable for certain agents. Let me call them 'Moorean propositions'. The structural unknowability of Moorean propositions is normally taken to pave the way towards proving a familiar paradox from epistemic logic, the so-called 'Knowability Paradox', or 'Fitch´s Paradox', which purports to show that if all truth are knowable, then all truth are in fact known. The present paper explores how to translate Moorean statements into a probabilistic language. A successful translation should preserve fundamental traits of standard Moorean propositions; in particular, adequate translations should enable us to derive a version of Fitch´s Paradox in a probabilistic setting. I offer a suitable schematic form for probabilistic Moorean propositions, as well as a concomitant proof of a probabilistic Knowability Paradox. To do so I rely on a Kripke framework enriched with evidential probabilities. The framework provides a unified account for both knowledge and probability attributions; we can then think of possible refinements of the basic setting, which may lead to a unified solution for the two versions of the paradox. Moreover, I argue that traditional candidates to play the role of probabilistic Moorean propositions will not do, precisely because they are not structurally unknowable in the chosen framework. In particular, we can show that violations of the so-called 'Reflection Principle' in probability (as discussed for instance by van Fraassen) need not yield structurally unknowable propositions. Among other things, this should lead us to question whether violating the Reflection Principle actually amounts to a clear case of epistemic irrationality, as it is often assumed. This result challenges the importance of the principle as a tool to assess both synchronic and diachronic rationality, a topic which is largely independent of Fitch´s Paradox, from a somewhat unexpected source.","palabras_clave":"Fitch's Paradox|Reflection Principle|Epistemic Logic|Knowability"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":34452,"idioma_id":4,"titulo":"A Worldwide Phylogenetic Classification of the Poaceae (Gramineae)","resumen":"We present a new worldwide phylogenetic classification of 11 506 grass species in 768 genera, 12 subfamilies, seven supertribes, 52 tribes, five supersubtribes, and 90 subtribes; and compare two phylogenetic classifications of the grass family published in 2015 (Soreng et al. and Kellogg). The subfamilies (in descending order based on the number of species) are Pooideae with 3968 species in 202 genera, 15 tribes, and 30 subtribes; Panicoideae with 3241 species in 247 genera, 13 tribes, and 19 subtribes; Bambusoideae with 1670 species in 125 genera, three tribes, and 15 subtribes; Chloridoideae with 1602 species in 124 genera, five tribes, and 26 subtribes; Aristidoideae with 367 species in three genera, and one tribe; Danthonioideae with 292 species in 19 genera, and one tribe; Micrairoideae with 184 species in eight genera, and three tribes; Oryzoideae with 115 species in 19 genera, four tribes, and two subtribes; Arundinoideae with 40 species in 14 genera, two tribes, and two subtribes; Pharoideae with 12 species in three genera, and one tribe; Puelioideae with 11 species in two genera, and two tribes; and the Anomochlooideae with four species in two genera, and two tribes. We also include a radial tree illustrating the hierarchical relationships among the subtribes, tribes, and subfamilies. Newly described taxa include: supertribes Melicodae and Nardodae; supersubtribes Agrostidodinae, Boutelouodinae, Gouiniodinae, Loliodinae, and Poodinae; and subtribes Echinopogoninae and Ventenatinae.","palabras_clave":"classification|DNA|Gramineae|grasses|morphology| phylogeny"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":34865,"idioma_id":5,"titulo":"Indicadores de Productividad en Hospitales Públicos","resumen":"El hospital público es el gran receptor por excelencia en lo que se refiere a traumatizados, pero dicha excelencia parece desvanecerse ante las malas condiciones edilicias y los procesos ineficientes, producto, tal vez, del imponente mensaje actual que establece que la salud pública debe ser solo para los indigentes, actuando como un hospital indigente en sí mismo.Esta investigación aborda el análisis de eficiencia de esta entidad no lucrativa del sector público sanitario en función de indicadores como herramienta útil de gestión. Se determinó que el resultado de la actividad del hospital público como entidad no lucrativa no suele ser un output tangible, sino el cumplimiento de unos objetivos en la prestación de un conjunto de servicios a la comunidad. La contribución de las mismas al bienestar social resultaría el punto de referencia último para orientar la asignación de recursos destinada a satisfacer las necesidades de la población.El objetivo de este trabajo es elaborar indicadores de gestión desde una perspectiva interna y externa que permitirá la  consecución y el seguimiento de la estrategia, y como consecuencia mejorar el servicio de salud. Esta matriz  de indicadores permitirá  presentar la realidad de la institución en un instante determinado.Este artículo presenta indicadores específicos de la gestión hospitalaria relacionados con el área de internación, como parte integrante del cuadro de mando desarrollado.","palabras_clave":"Indicadores|gestion|Productividad|Hospital"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":34891,"idioma_id":4,"titulo":"EFFECT OF THE SUPPORT AND PROMOTERS IN FISCHER-TROPSCH SYNTHESIS USING SUPPORTED FE CATALYSTS","resumen":"The effect of support and promoters on the catalytic propertiesof Fe supported in the FTS was studied. Precursors of supported Fe onSiO2 and SBA -15 were synthesized and doped with Cu and K. The precursorswere activated in pure H2 and catalytically tested with a mixture ofH2:CO=2:1, T=543K and P=10bar. The samples were characterized by atomicabsorption, N2 adsorption, X-ray diffraction, TEM spectroscopy and TPR.Also, we used the DFT to study the changes of the electronic structurewhen the Fe, K and Cu are adsorbed on the SBA-15 surface. Theincorporation of different ions do not alter the structural and texturalproperties of the support. In the FTS, all the catalysts supported onSBA-15 presented a low selectivity towards methane and a promisinghydrocarbon production in the range of gasoline, showing positive effectof the support for iron catalysts for the FTS reaction. The activityorder obtained was: Fe\/K-SBA-15> Fe\/Cu-SBA-15 &#8776; Fe-SBA-15 > Fe-SiO2,which is the same order for the selectivity towards olefins. The presenceof K on the SBA-15 surface increases the activity and selectivity towardsolefins; an effect that can be attributed to the electrostatic effectgenerated by the alkaline ions.","palabras_clave":"Fischer Tropsch|Supported Fe|Potassium|Cupper"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35044,"idioma_id":4,"titulo":"'The Rise of the Textile District of Buenos Aires and the limits of Import Substitution Industrialization in the first half of 20th Century'","resumen":"This paper analyzes the origins of the textile district of Buenos Aires in the first half of the 20th Century. In this period, the cotton industry led the import substituting industrialization. This industrial development accentuated the characteristics that the industrial location had assumed in the Argentina; especially the spatial concentration in the city of Buenos Aires and the outskirts. It is supported that this case adapts it partially to the industrial district model. Although the industrial concentration in Buenos Aires, allowed to the argentine textile industry to benefit of the external economies defined by Marshall, the industrial growth assumed typical forms of the ?late, late industrialization? analyzed by Albert Hirschman. On this subject, the article analyzes the factors that shaped the rising of the industrial district and limits of the Import Substitution Industrialization model imposed on the industrial agglomeration advantages.","palabras_clave":"TEXTILE INDUSTRY|INDUSTRIAL DISTRICT|IMPORT SUBSTITUTION INDUSTRIALIZATION|ARGENTINA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35129,"idioma_id":5,"titulo":"Estudio crítico sobre el libro: Rivera Castro, Faviola, Virtud, felicidad y religión en la filosofía moral de Kant, México, IIF, UNAM, 2014","resumen":"Se trata de un estudio crítico sobre el libro de Rivera Castro, Faviola, Virtud, felicidad y religión en la filosofía moral de Kant, México, IIF, UNAM, 2014. Se presenta una serie de críticas metodológicas.","palabras_clave":"KANT|FELICIDAD|BIEN SUPREMO|VIRTUD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35216,"idioma_id":4,"titulo":"Novel tactics for neuroprotection in Parkinson?s disease: Role of antibiotics, polyphenols and neuropeptides","resumen":"Parkinson?s disease is a progressive neurodegenerative disorder characterized by the degeneration ofmidbrain nigral dopaminergic neurons. Although its etiology remains unknown, the pathological role ofseveral factors has been highlighted, namely oxidative stress, neuroinflammation, protein misfolding,and mitochondrial dysfunction, in addition to genetic predispositions. The current therapy is mainlysymptomatic with L-DOPA aiming to replace dopamine. Novel therapeutic approaches are beinginvestigated with the intention of influencing pathways leading to neuronal death and dysfunction. Thepresent review summarizes three novel approaches, the use of which is promising in pre-clinical studies.Polyphenols have been shown to possess neuroprotective properties on account of their well-establishedantioxidative and anti-inflammatory actions but also due to their influence on protein misfolding andmitochondrial homeostasis. Within the amazing ancillary effects of antibiotics, their neuroprotectiveproperties against neurodegenerative and neuroinflammatory processes are of great interest for thedevelopment of effective therapies against Parkinson?s disease. Experimental evidence supports thepotential of antibiotics as neuroprotective agents, being useful not only to prevent the formation of toxica-synuclein oligomers but also to ameliorate mitochondrial dysfunction and neuroinflammation.Neuropeptides offer another approach with their diverse effects in the nervous system. Among them,pituitary adenylate cyclase-activating polypeptide, a member of the secretin\/glucagon superfamily, hasseveral advantageous effects in models of neurodegeneration, namely anti-apoptotic, anti-inflammatoryand antioxidant actions, the combination of which offers a potent protective effect in dopaminergicneurons. Owing to their pleiotropic modes of action, these novel therapeutic candidates have potential intackling the multidimensional features of Parkinson?s disease.","palabras_clave":"POLYPHENOLS|ANTIBIOTICS|ANTIOXIDANTS|PACAP"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35547,"idioma_id":5,"titulo":"Grandes maestros: una aproximación al estudio de la identidad docente en la Facultad de Humanidades de la UNMdP","resumen":"Este trabajo se inscribe la trayectoria de diez años de investigaciones delGrupo de Investigaciones en Educación y Estudios Culturales, que se hadedicado a la indagación sobre la buena enseñanza y los profesoresmemorables en la UNMDP mediante el método biográfico-narrativo. En estecontexto, nos abocamos a develar el desarrollo de la identidad profesionaldocente desde su surgimiento y a lo largo de las trayectorias de vida degrandes maestros señalados como tales por los estudiantes de losprofesorados de la Facultad de Humanidades de la UNMDP. Abordamos enaquí narrativas biográficas que dan voz a los docentes permitiéndoles de estemodo la expresión de su identidad, que asumimos en su carácter situadohistórica y socialmente y que, como toda identidad se presenta de manerafluida, siempre en continua formación. La perspectiva biográfico narrativa nospermitirá incorporar a la indagación sobre buenas prácticas docentes lastrayectorias de vida los docentes, entrelazando su vida personal y profesionalLa mirada retrospectiva de los docentes sobre este entramado identitariopersonal y profesional deja aflorar sus modos de ser y conocer, y permiten unacomprensión más profunda de sus prácticas. El interés en el tema radica en lacentralidad que la configuración de dicha identidad implica para el proceso dela formación del profesorado y la vida profesional docente.","palabras_clave":"IDENTIDAD DOCENTE|FORMACIÓN DOCENTE|NARRATIVA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35581,"idioma_id":4,"titulo":"Histomorphologic and ultraestructural recovery of miophaty in rats treated with Low Lever Laser Therapy","resumen":"The purpose of the present work was to study the effect of Low Level Laser Therapy (LLLT): Helium-Neon (He-Ne) and Gallium Arsenide (Ga-As) laser on the histomorphology of muscle and mitochondria in experimental myopathy in rats. Thirty Suquía strain female rats were distributed in groups: A) control (intact), B) injured, C) injured and treated with He-Ne laser, D) injured and treated with Ga-As laser, E) irradiated with He-Ne laser on the non-injured muscle, and F) irradiated with Ga-As laser on the non-injured muscle.Myopathy was induced by injecting 0.05 mg\/rat\/day of adrenaline in the left gastrocnemius muscle at the same point on 5 consecutive days, in groups B, C and D. LLLT was applied with 9.5 J.cm-2 daily for 7 consecutive days in groups C, D, E and F. The muscles were examined with optic and electronic microscopy. The inflammation was classified as: absent, mild and intense and the degree of mitochondrial alteration was graded I, II, III and IV. Categorical data were statistically analyzed by Chi-square and the Fisher-Irwin Bilateral test, setting significant difference at p <0.05.  The damage found in muscle and mitochondria histomorphology in animals with induced myopathy (B) was intense or severe inflammation with grade III or IV of mitochondrial alteration. They underwent significant regression (p<0.001) compared with the groups treated with He-Ne (C) and Ga-As (D) laser, in which mild or moderate inflammation was seen and mitochondrial alteration grade I and II, recovering normal myofibrillar architecture. No differences were found between the effects caused by the two lasers, or between groups A, E and F. Group A was found to be different from B, C and D (p<0.001). LLLT in experimental myopathy caused significant muscular and mitochondrial morphologic recovery.","palabras_clave":"LASER|MIOPHATY|RECOVERY|RATS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35600,"idioma_id":5,"titulo":"La comunicación entre padres e hijos: su influencia sobre el disfrute y el flow adolescente","resumen":"El objetivo de este trabajo fue estudiar la influencia de la comunicación con los padres  sobre las actividades de disfrute y las experiencias óptimas (flow) en adolescentes.  Participaron 159 adolescentes de ambos géneros (37.7% varones) de tres escuelas públicas  de Buenos Aires, Argentina (edad M = 14.7; DE = 1.7). Se realizaron correlaciones de  Pearson, regresiones lineales simples y múltiples y regresiones logísticas. Los resultados  mostraron que una comunicación positiva (más abierta y con menos problemas) con ambos  padres predice el disfrute y el tiempo dedicado a actividades estructuradas, como el deporte  o las actividades artísticas. Sólo menores problemas en la comunicación con el padre,  predicen un mayor tiempo dedicado a las actividades sociales. Estos resultados se discuten  en función de la importancia de la comunicación con ambos padres para el disfrute y la  experiencia óptima de flow en las actividades que realizan los adolescentes.  Palabras clave: comunicación adolescente-padres - actividades diarias - disfrute - flow  (estado de conciencia).","palabras_clave":"COMUNICACIÓN|ACTIVIDADES|DISFRUTE|FLOW"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35603,"idioma_id":5,"titulo":"Adaptación argentina del Inventario de Fortalezas en adolescentes (VIA-Youth): Propiedades psicométricas y alternativas para su factorización","resumen":"El Values in Action Inventory of Strenghts for Youth (VIA-Youth) es un instrumento desarrollado para evaluar las fortalezas humanas en adolescentes. Este trabajo se propone presentar el proceso de adaptación de dicho instrumento para su uso con adolescentes de Argentina. En la primera etapa, se logró la adaptación lingüística y conceptual. En la segunda etapa, se aplicó la versión local de la escala a una muestra de 542 adolescentes (varones = 45.40%; mujeres = 54.60%), con una edad media de 14.92 (DT = 1.79) que asistían a escuelas públicas y privadas. Se estudió la capacidad de discriminación de los ítems y la fiabilidad. Con el objetivo de estudiar la validez de constructo se realizaron dos análisis factoriales exploratorios (AFE) mediante procedimientos diferentes. Se discuten los resultados a la luz de las recomendaciones actuales sobre AFE y la factorización encontrada para el uso del VIA-Youth en esta población de adolescentes. Indexación: Psicodoc; PsycINFO; Latindex; Cengage; Ebsco; Scopus; Thomson Reuters Web of Science.","palabras_clave":"FORTALEZAS|ADOLESCENTES|ADAPTACIÓN|ANÁLISIS PARALELOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35605,"idioma_id":4,"titulo":"The Sensation Seeking Scale (SSS-V) and its use in Latin American adolescents. Alcohol consumption pattern as an external criterion for its validation","resumen":"Sensation Seeking is a trait defined by the seeking of varied, novel, complex, and intense situations and experiences, and the willingness to take physical, social, and financial risks for the sake of such experience. The Sensation Seeking Scale (SSS-V) is the most widely used measure to assess this construct. In previous studies a variety of psychometric limitations were found when using the SSS-V with Latin American population. The purpose of this study is to present additional psychometric properties for its use with Latin American adolescents. It was applied to a 506 adolescent sample (from 12 to 20 years). The result is a scale of 22 items that cover four factors. It seems that sensation seeking among Latin American adolescents can be described in terms of four factors, but with some slightly content differences from what is usually found in adult samples from other countries. Future lines of research are proposed. Indexada en: Scopus, EBSCO, PsycEXTRA, DOAJ, ProQuest.","palabras_clave":"BUSQUEDA DE SENSACIONES|ALCOHOL|ESCALA|ADOLESCENCIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35607,"idioma_id":5,"titulo":"¿Cómo perciben los adolescentes de la Ciudad de Buenos Aires su futuro? Una mirada desde sus actores","resumen":"La forma en que los adolescentes perciben su futuro tiene una gran importancia para un desarrollo positivo. Este trabajo se propone conocer y comprender cómo un grupo de adolescentes escolarizados de la Ciudad Autónoma de Buenos Aires percibe su futuro. Se realizó un estudio de tipo exploratorio-descriptivo con metodología cualitativa y un diseño transversal. Se trabajó con una muestra intencional de 24 adolescentes (M = 16.10; DE = 1.10) de ambos sexos (mujeres = 54.20%). Se realizaron entrevistas individuales y grupos focales. Se realizó un análisis de contenido temático con los datos recolectados. Se encontraron dos grandes temas respecto de la percepción del futuro en los adolescentes. El primero se refiere a la imagen que los adolescentes tienen de su futuro. Sus componentes son: valoración, contenido y grado de claridad de la imagen del futuro. El segundo, hace referencia a la forma en que los adolescentes construyen su futuro. Sus  componentes son: ocuparse del futuro, entornos en los que los adolescentes construyen su futuro, influencia de la familia y valoración del proyecto. Un hallazgo emergente es que los adolescentes difieren en la descripción que hacen de ellos mismos, de sus pares cercanos o de los otros adolescentes en general. Indexación: Publindex (A2) Colombia, Lilacs - Bireme, Ops, Psicodoc - COP de España, Redalyc, UAM México, SCIELO Colombia, Web Of Knowledge, entre otras.","palabras_clave":"ESTUDIO CUALITATIVO|FUTURO|ADOLESCENCIA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35610,"idioma_id":5,"titulo":"Estudio exploratorio acerca de las fortalezas humanas en deportistas adolescentes de Selecciones Nacionales Argentinas","resumen":"Las fortalezas humanas son un conjunto de atributos positivos que se manifiestan en los pensamientos, sentimientos y en la conducta. El objetivo de este trabajo fue describir las fortalezas humanas de los adolescentes deportistas de Selecciones Nacionales Argentinas y compararlas con adolescentes de otros niveles de práctica. Participaron 721 adolescentes de ambos sexos (47.60% varones; 52.40% mujeres), de entre 11 y 19 años de edad (M = 15.27; DE = 1.53), pertenecientes a Selecciones Nacionales Argentinas (n = 238), adolescentes que realizaban deporte como actividad recreativa extracurricular (n = 238) y adolescentes que no practicaban deporte (n = 245). Instrumentos: cuestionario socio-demográfico e Inventario de Fortalezas para adolescentes (VIA-Youth). Se encontraron diferencias en las fortalezas en función del sexo, la edad, el tipo de deporte y el nivel competitivo. Se discuten los resultados en función del rol del deporte de élite en el desarrollo positivo de los adolescentes.","palabras_clave":"FORTALEZAS|DEPORTISTAS|ALTO RENDIMIENTO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":35652,"idioma_id":5,"titulo":"Estrategias gremiales frente a la precarización laboral. Las luchas de los obreros aceiteros de Rosario por el pase a planta de los trabajadores tercerizados","resumen":"En el sector aceitero, durante la década de 1990, se introdujeron políticas empresariales tendientes a precarizar de trabajo, entre las que se ubica la tercerización laboral mediante la ampliación de la incorporación de trabajadores dependientes de empresas contratistas para realizar tareas habituales en las plantas industriales. En este contexto, el Sindicato de Rosario emprendió diferentes procesos de lucha y desarrolló estrategias gremiales que le permitieron obtener el pase a planta de un conjunto de trabajadores tercerizados.En este artículo se avanza en el análisis de los posicionamientos y accionar del gremio aceitero desde un abordaje centrado en la historización de los procesos de lucha y organización, y en la cotidianeidad laboral. Esta perspectiva permitirá ponderar la dinámica gremial desarrolladas durante los años ?90 como dimensión central para abordar la conflictividad laboral en décadas recientes; y, fundamentalmente, para comprender y explicar las conquistas alcanzadas contra las tercerizaciones y por aumentos salariales.","palabras_clave":"PRECARIZACIÓN LABORAL|TERCERIZACIONES|ESTRATEGIAS GREMIALES|TRABAJADORES ACEITEROS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":36216,"idioma_id":5,"titulo":"¿El Griphus Ternarii Numeri de Ausonio: juego retórico o miscelánea gnóstico-neoplatónica?","resumen":"D. Ausonio fue un poeta de origen galo quien, a partir del ejercicio de la gramática y la retórica, favoreció la recuperación de los moldes del pasado, dando cuenta de que la literatura tardoantigua no fue una mera repetición de preceptos cristalizados sino una labor de reflexión y producción novedosa. Nacido a comienzos del s. IV d. C., Ausonio se dedicó a la formación académica de los miembros pertenecientes a las élites imperiales y destinó parte de su tiempo a la producción poética.El poema del que nos ocuparemos, el Griphus Ternarii Numeri, es una composición breve, constituida por noventa hexámetros, la cual está prologada por una carta dirigida a Símaco, integrante de uno de los últimos clanes paganos de formación neoplatónica, con el que Ausonio mantenía una fluida comunicación. Esta epístola, según la costumbre de su autor, se caracteriza por ser un medio de expresiones metaliterarias; en este caso adoptando una máscara humilis, Ausonio banaliza la materia de su poema al considerarla adecuada a discusiones simposíacas y, para sellar esta característica de género, se vale de alusiones y citas de autores clásicos.","palabras_clave":"AUSONIO|SÍMACO|NEOPLATONISMO|ENIGMA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":36543,"idioma_id":4,"titulo":"Influence of organic additives on the behaviour of zinc electroplating from alkaline cyanide-free electrolyte","resumen":"Two similar polymeric organic compounds from the polyquaternium family were studied as levelling additives in an alkaline cyanide-free zinc plating electrolyte. One additive (LA) has amide bonds between its monomers and the other (LU) has urea unions in its chemical structure. Copper cementation on zinc and gas evolution during aging of the zinc coatings were used to evaluate the effect of the chemical structure of the organic additives on the characteristic deleterious aging process of the coatings when electrodeposited with LA. Scanning electron microscopy and X-ray diffraction were used to follow surface morphology and crystallographic modifications of the coatings during aging. Faster copper cementation kinetics, zinc whiskers growth, blistering of the coating and N2, CH4, CO2and H2evolution were observed during accelerated aging of the coatings when LA was used. The coatings produced with LU did not show any aging effect. These studies show the strong influence that subtle changes in the chemical structure of the organic additive may have on the performance of zinc coating during storage.","palabras_clave":"electroplating|Zinc|organic aditive"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":36590,"idioma_id":5,"titulo":"Notas sobre las experiencias de lucha obrera hacia la década de 1960 en el norte de Salta y su influencia sobre las protestas recientes","resumen":"La evidencia reunida en este trabajo indica que la durante la década de 1960 el movimiento obrero del norte de Salta desarrolló procesos de lucha y organización en los que se registró una actuación significativa del Partido Comunista. En particular, se analiza la lucha contra el Plan Larkin y se evalúa brevemente la conformación de la CGTA en la región. Es posible rastrear la incidencia de esas experiencias sobre las luchas que se produjeron a partir de los años 1990.","palabras_clave":"NORTE de SALTA|LUCHAS OBRERAS|DÉCADA de 1960|PROTESTAS SOCIALES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":37530,"idioma_id":4,"titulo":"On abstract normalisation beyond neededness","resumen":"We study normalisation of multistep strategies, strategies that reduce a set of redexes at a time, focussing on the notion of necessary sets, those which contain at least one redex that cannot be avoided in order to reach a normal form. This is particularly appealing in the setting of non-sequential rewrite systems, in which terms that are not in normal form may not have any needed redex. We first prove a normalisation theorem for abstract rewrite systems or ARS, a general rewriting framework encompassing many rewriting systems developed by P-A.Melliès. The theorem states that multistep strategies reducing so called necessary and non-gripping sets of redexes at a time are normalising in any ARS. Gripping refers to an abstract property reflecting the behavior of higher-order substitution. We then apply this result to the particular case of the Pure Pattern Calculus, a calculus of patterns; and to the lambda-calculus with parallel-or.","palabras_clave":"Rewriting|Normalisation|Non-sequential Calculi|Pattern Calculi"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":37679,"idioma_id":5,"titulo":"Textoplasma. La imagen como fantasma de la escritura en la obra de Mario Bellatin","resumen":"La relación que las imágenes establecen con la escritura en varias novelas de Mario Bellatin (Jacobo el mutante, Perros héroes, Biografía ilustrada de Mishima, Los fantasmas del masajista, entre otras) va algo más allá de la función que cumplían en una novela como Nadja de André Breton o los títulos de W. G. Sebald que en cierto modo volvieron a instalar el diálogo entre imagen y palabra en la literatura reciente. En el caso de Bellatin, más allá de su propia autofiguración performativa y de las complejas operaciones relativas al libro como soporte, las imágenes oscurecen y problematizan el texto que se supone ilustran ofreciéndose como un suplemento que enfatiza las cualidades perturbadoras o fantasmáticas de la narración, sin perder su intención irónica. A la luz de las teorías de Hans Belting, Reinaldo Laddaga o W. T. Mitchell, este trabajo pretende estudiar la relación entre palabra e imagen en este autor, cuya obra parece postular un modo muy contemporáneo de las prácticas vanguardistas.","palabras_clave":"MARIO BELLATIN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":43656,"idioma_id":4,"titulo":"Effect of Human Serum on Biofilm Formation by Oral Mycoplasma on Nitinol Surfaces","resumen":"Intoduction: Dental plaque harbors microorganisms that can enter the blood stream due to bacteremia, and reach heart prosthetic devices and become secondary septic foci. The presence of Mycoplasma in gingival-periodontal plaque and the ability of Mycoplasma to adhere to nitinol surfaces in cultures with horse serum have been documented. Human serum, a source of cholesterol, may promote Mycoplasma colonization of prosthetic devices.Objective: To study the effect of human serum on biofilm formation by Mycoplasma on Nitinol® surfaces, using scanning electron microscopy (SEM).Materials and methods: Sixty samples of nitinol were suspended in PPLO broth supplemented with 20% human serum, inoculated with Mycoplasma spp., and incubated under anaerobiosis for 5 days. The samples were then washed with sterile distilled water and processed for observation by SEM. Nitinol samples suspended in PPLO broth supplemented with 20% horse serum and inoculated with Mycoplasma spp. served as control.Results: Mycoplasma spp. formed biofilms on all nitinol surfaces; the biofilms mostly consisted of cells undergoing cell division. Given a 95% confidence interval and a sample size of n=60, the lower confidence bound on the percentage of positive cases was 94%. The results showed that human serum enhanced biofilm formation by Mycoplasma on nitinol surfaces.","palabras_clave":"BIOFILM|HUMAN SERUM|MYCOPLASMA |NITINOL"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":44193,"idioma_id":4,"titulo":"Theoretical Study of Hydrogen Adsorption on Ru-Decorated (8,0) Single-Walled Carbon Nanotube","resumen":"&amp;amp;amp;lt;!-- \/* Font Definitions *\/@font-face{font-family:'&amp;amp;amp;#65325;&amp;amp;amp;#65331; &amp;amp;amp;#26126;&amp;amp;amp;#26397;';mso-font-charset:78;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:1 134676480 16 0 131072 0;}@font-face{font-family:'&amp;amp;amp;#65325;&amp;amp;amp;#65331; &amp;amp;amp;#26126;&amp;amp;amp;#26397;';mso-font-charset:78;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:1 134676480 16 0 131072 0;}@font-face{font-family:Cambria;panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:-536870145 1073743103 0 0 415 0;} \/* Style Definitions *\/p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-unhide:no;mso-style-qformat:yes;mso-style-parent:'';margin:0cm;margin-bottom:.0001pt;mso-pagination:widow-orphan;font-size:12.0pt;font-family:Cambria;mso-fareast-font-family:'&amp;amp;amp;#65325;&amp;amp;amp;#65331; &amp;amp;amp;#26126;&amp;amp;amp;#26397;';mso-bidi-font-family:'Times New Roman';}p.MsoPlainText, li.MsoPlainText, div.MsoPlainText{mso-style-priority:99;mso-style-link:'Plain Text Char';margin:0cm;margin-bottom:.0001pt;mso-pagination:widow-orphan;font-size:10.5pt;font-family:Courier;mso-fareast-font-family:'&amp;amp;amp;#65325;&amp;amp;amp;#65331; &amp;amp;amp;#26126;&amp;amp;amp;#26397;';mso-bidi-font-family:'Times New Roman';}span.PlainTextChar{mso-style-name:'Plain Text Char';mso-style-priority:99;mso-style-unhide:no;mso-style-locked:yes;mso-style-link:'Plain Text';mso-ansi-font-size:10.5pt;mso-bidi-font-size:10.5pt;font-family:Courier;mso-ascii-font-family:Courier;mso-hansi-font-family:Courier;}.MsoChpDefault{mso-style-type:export-only;mso-default-props:yes;font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:Cambria;mso-ascii-font-family:Cambria;mso-fareast-font-family:'&amp;amp;amp;#65325;&amp;amp;amp;#65331; &amp;amp;amp;#26126;&amp;amp;amp;#26397;';mso-hansi-font-family:Cambria;}@page WordSection1{size:612.0pt 792.0pt;margin:72.0pt 90.0pt 72.0pt 90.0pt;mso-header-margin:36.0pt;mso-footer-margin:36.0pt;mso-paper-source:0;}div.WordSection1{page:WordSection1;}--&amp;amp;amp;gt;First-principles calculations based on the densityfunctional theory (DFT) were applied to study the H2 adsorption onAu@Pd NP (core@shell icosahedral bimetallic nanoparticle). The calculationsindicate that, for almost all adsorption sites, there is no energy barrier forH2 dissociation at the surface of Au@Pd NP, and the H2molecule spontaneously dissociate. The only exceptions are the case of atopfrom edge (AE) and atop from vertex (AV) sites, where there are no-dissociationat all. Looking at the adsorption energies, dissociated cases are 1.3 eV morestable than non-dissociated cases. The work function (WF) values associated toNP with H2 adsorbed are lower than the obtained in the case ofPd\/Au(111) surface. When H2 is dissociated on the NP or surface theWF increases while in the non dissociated case decrease. We also considered thechanges in hydrogen adsorption and dissociation in mixed shell NP structures.The atomic H penetration was also studied for Au@Pd NP.&nbsp;&nbsp; Hydrogen adsorptionon both, Au@Pd NP and Pd\/Au(111) surface, systems lead to slight shift of Pd´sd states to lower energies, while the s and p states are almost unaffected. Ahigher hybridization between Pd and H is detected in the NP case. Each H atomof the H2 molecule adsorbed on the NP becomes negatively charged.Seem that the charge transference occurs toward the NP. The bond order onorbital population analysis indicates no bond for H-H and a decrease in themetal-metal bond while a Pd-H bond is formed.","palabras_clave":"semiconducting SWCNT |Ruthenium|Hydrogen storage|DFT"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":45859,"idioma_id":4,"titulo":"The relationship between executive functions and fluid intelligence in euthymic Bipolar Disorder patients","resumen":"Distinct cognitive deficits have been described in Bipolar disorder (BD), including executive impairments, commonly attributed to frontal dysfunction. However, recent attention has been paid to the heterogeneity of cognitive functioning in this population, suggesting that the executive deficits observed in BD might be due to a loss in fluid intelligence (g). Following our previous line of investigation in multiple neurological and psychiatric conditions we aimed at determining the role of g in frontal deficits in BD. Euthymic BD patients (n = 51) and healthy controls (n = 37) were assessed with Wisconsin Card Sorting Test (WCST), Verbal Fluency, Trail Making Test B (TMTB), a multitasking test, and a theory of mind test. A general cognitive battery was used to derive a measure of g. As in other neuropsychiatric conditions, significant patient-control differences in WCST, Verbal Fluency and TMTB were removed when g was introduced as a covariate. Deficits remained significant in the multitasking test. We suggest that neuropsychological assessment in BD should include tests of general intelligence, together with one or more specific tasks that allow for the assessment of residual frontal deficits, putatively associated with anterior frontal functioning.","palabras_clave":"executive function|fluid intelligence|schizophrenia|frontal lobe|multitasking|decision making"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":49082,"idioma_id":5,"titulo":"En busca de una identidad nacional","resumen":"tres bailarines españoles de visita por argentina hablan sobre la identidad en el flamenco, Maria Juncal, Manuela Rios y Alvaro Madrid.","palabras_clave":"mariana astuti|nuevo flamenco festival"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":49953,"idioma_id":4,"titulo":"EFFECTS OF RECREATIONAL ACTIVITIES ON PATAGONIAN ROCKY SHORES","resumen":"Recreational activities can be an important source of anthropogenic disturbance in intertidal benthic assemblages. On rocky shores, activities such as trampling, snorkeling and the handling of organisms may have a negative effect on benthic communities by modifying the abundance and distribution of key species. Here, we describe and quantify impacts due to recreational activities on benthic communities on a Patagonian rocky shore by investigating their resilience to two types of human disturbance: vehicle traffic and human trampling. To evaluate the effects of these activities, we carried out an observational study and assessed post-disturbance assemblage recovery. The rocky shores is most intensively visited during summer, and marked differences in the distribution and abundance of benthic species among disturbed and control plots were found after this season. The benthic community on the high intertidal was weakly impacted by disturbance generated due to vehicle traffic in summer (one vehicle on a single occasion, pulse disturbance); which did not affect the cover of dominant species. This suggests that the high intertidal community would be resistant to the passage of one vehicle on a single occasion. The effects of continuous trampling (press disturbance) were drastic and the community of the mid intertidal level did not recover before the next recreational season. Mid intertidal communities exposed to press disturbances require more than one tourist season of human inactivity to recover from anthropogenic effects, suggesting that resilience mechanisms in this community operate at broad timescales. Our findings highlight the need to establish and implement management actions that contemplate the nature of the disturbance and intertidal level to minimize habitat degradation due to human recreational activities.","palabras_clave":"ROCKY REEFS|HUMAN IMPACTS|DISTURBANCE|SCUBA DIVING|TOURISM|MARINE INVERTEBRATE|ALGAE|PATAGONIAN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":50538,"idioma_id":5,"titulo":"¿Cómo investigar un problema que involucra a distintas disciplinas? (propuestas para la investigación en bioética)","resumen":"Cómo investigar desde diferentes disciplinas tomando como variables la contextualización del problema abordado. Breve historia de la bioética.","palabras_clave":"ciencia|ética|investigación | interdisciplinariedad"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":50903,"idioma_id":5,"titulo":"La comunicación entre padres e hijos: Su influencia sobre el disfrute y el flow adolescente","resumen":"El disfrute y la experiencia óptima de flow constituyen experiencias subjetivas de relevancia para un desarrollo positivo durante la adolescencia. Los padres, como principal contexto de socialización en esta etapa, adquieren un rol fundamental en la facilitación de estas experiencias positivas. El objetivo de este trabajo fue estudiar la influencia de la comunicación con los padres sobre las actividades de disfrute y las experiencias óptimas (flow) en adolescentes. Participaron 159 adolescentes de ambos sexos (37.7% varones) de tres escuelas públicas de Buenos Aires (edad M = 14.7; DE = 1.7). Se realizaron correlaciones de Pearson, regresiones lineales simples y múltiples y regresiones logísticas. Los resultados mostraron que una comunicación positiva (más abierta y con menos problemas) con ambos padres predice el disfrute y el tiempo dedicado a actividades estructuradas, como el deporte o las actividades artísticas. Sólo menores problemas en la comunicación con el padre, predicen un mayor tiempo dedicado a las actividades sociales. Estos resultados se discuten en función de la importancia de la comunicación con ambos padres para el disfrute y la experiencia óptima de flow en las actividades que realizan los adolescentes.  Indexada en: ScIELO, Redalyc, EBSCO, Latindex, DOAJ.","palabras_clave":"COMUNICACION|ADOLESCENTES-PADRES|DISFRUTE|FLOW"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":51001,"idioma_id":5,"titulo":"La experiencia de teis","resumen":"Con motivo de celebrarse en el 2017, el 40° aniversario de la creación del Departamento de Turismo, se dará a conocer en este artículo un proyecto de extensión del mismo, desarrollado a lo largo de los últimos once años, y que forma parte de los proyectos permanentes de la Secretaría de Extensión y Vinculación Tecnológica de la Facultad de Humanidades y Ciencias Sociales de la Universidad Nacional de Misiones. El mismo tuvo inicio formal en el año 2007 y continúa vigente hasta la actualidad, siendo aprobado por Disposiciones Nº 137\/06 y Nº 074\/10 del Honorable del Consejo Directivo.El proyecto consiste en un ciclo de conferencias, charlas, debates y mesas redondas, en los que se busca la transferencia de conocimientos, difusión y capacitación de diferentes temáticas vinculadas al turismo, y destinado principalmente a estudiantes y egresados de las carreras de turismo, pero abierto a todos los claustros y comunidad en general.Este escrito permitirá hacer un repaso de la evolución de este proyecto a lo largo de once años consecutivos de desarrollo, describiendo sus inicios, temáticas abordadas, público destinatario, proceso de gestión y organización de los encuentros.","palabras_clave":"investigacion|tesis|experiencia|tesistas"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":51018,"idioma_id":4,"titulo":"Union Organizing after the Collapse of Neoliberalism in Argentina: The Place of Community in the Revitalization of the Labor Movement (2005&ndash;2011)","resumen":"Recent Argentine history showed that since 2003 the labor movement became increasingly relevant due to protests organized by unionized formal workers. Labor revitalization in a context of persistent informality raised the following question: Were there union organizing strategies that related formal workers to the broader working class community that included informal workers? This article answered the question through the analysis of union strategies from three formal sector firms located in one city of the Northern Gran Buenos Aires, Argentina, between 2005 and 2011. The evidence from this comparison showed that in two of the factories there were union strategies to reach the community. The existence of a grassroots democratic union in the shop floor appeared as a necessary condition for inclusive union strategies. The scale of those relations varied according to the geographical pattern of workers? housing, which was the result of the company?s localization strategy.","palabras_clave":"WORKING CLASS|LABOR MOVEMENT|CLASS IDENTITY |POST-NEOLIBERALISM"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":51761,"idioma_id":5,"titulo":"cambio estructural y desarrollo productivo en sgo del estero .1194\/2007","resumen":"One of the features that distinguish the type of truncated transition in which someunderdeveloped economies such as those of Latin America are located is represented by thestructural heterogeneity, the result of processes of transformation that achieved high productivitydeployments in enclaves - detached from the internal market but integrated And a vast productivenetwork that does not reach adequate levels of competitiveness, in the context of an economy thatis still based on its natural resources. Santiago del Estero in the productive, is integrated as amarginal region of peripheral capitalism, where the process of productive modernization did notat any moment become a factor of change.In the period under study, which begins during the beginning of the cycle of the convertibilityboom (1994) and culminates with the end of the recovery phase of the model implemented afterthe fall of this plan (2007), Santiago del Estero recorded a rate of Growth of the Gross ProvincialProduct above the national rate. This was mainly due to the trend break in 2004.The study shows that structural change led to an acceleration of the growth rate of all activities,but labor market deficiencies, based mainly on a weak industrial sector, prevented breaking withlow level equilibria. Deforestation of the rural sector, which does not manage to be absorbed bythe manufacturing sector, generates a continuous tension in the labor market. The services sectorthen acted as a decompression valve and grew disproportionately, in informal activities and inpublic employment.","palabras_clave":"DESARROLLO PRODUCTIVO|HETEROGENEIDAD ESTRUCTURAL|CRECIMIENTO ECONOMICO"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":52173,"idioma_id":10,"titulo":"Análise interlinguística de gêneros textuais: contribuições para o ensino e a tradução","resumen":"Este artigo se situa na linha do interacionismo sociodiscursivo (Bronckart1997 e 2008b, entre outros) e tem o objetivo de propor uma via específi cade estudo de gêneros textuais: a análise de gêneros em uma perspectivacomparativa interlinguística. O trabalho começa refl etindo sobre anoção de gênero textual e a concepção específi ca do interacionismosociodiscursivo sobre os gêneros. Depois, as características da abordagemcomparativa de gêneros são apresentadas. Finalmente, observam-sealgumas potencialidades e contribuições signifi cativas dessa abordagempara o ensino de línguas e para a tradução. Os dados para alimentara discussão e exemplifi car as questões tratadas surgem de projetos depesquisa desenvolvidos em Portugal e na Argentina sobre gêneros diversos(e vinculados a diferentes atividades sociais \/ de linguagem) produzidosem português e espanhol.","palabras_clave":"géneros textuales|estudios comparados|interaccionismo sociodiscursivo"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":53124,"idioma_id":5,"titulo":"EXPERIENCIAS Y CONTEXTOS DE DESEMPEÑO PROFESIONAL DE LOS RECIENTES TITULADOS DEL PROFESORADO DE FILOSOFIA Y CS DE LA EDUCACIÓN (1996). Facultad de Humanidades. UNCa'","resumen":"El presente trabajo se enmarca dentro del proyecto de investigación ?La inserción y primeros desempeños profesionales docentes. Un estudio desde los graduados y alumnos avanzados de los profesores de Historia, Geografía, Ingles, Filosofía y Ciencias. de la Educación. Facultad de Humanidades- U.N.Ca.?. Dentro del campo de la formación docente, la noción ?docentes noveles?, refiere a la fase de inserción de los primeros años de desempeño docente en la enseñanza. Estos, se desarrollan en contextos laborales que emergen como espacios que impactan en la formación profesional, convirtiéndose en un proceso complejo en las que aparecen nuevos saberes y sentidos que van configurando los trayectos formativos. Nos preguntamos: ¿Cuáles son las debilidades y fortalezas del proceso formativo que perciben ante nuevos escenarios de inserción? ¿A qué herramientas acuden los docentes noveles al momento de insertarse a los contextos particulares de desempeño laboral? El estudio se inscribe en un enfoque cualitativo y es de carácter exploratorio, la recolección de los datos es a través de entrevistas semiestructurada a los recientemente titulados, cohorte 2011-2012 del Profesorado en Filosofía y Ciencias de la Educación (plan 1996) y que trabajan en escuelas secundarias e IES de la ciudad Capital de Catamarca. El tratamiento de los datos será a partir del análisis de contenidos y la triangulación de fuentes.","palabras_clave":"DOCENTES NOVELES |FORMACION PROFESIONAL |EXPERIENCIAS |PRIMEROS DESEMPEÑOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":53832,"idioma_id":5,"titulo":"Saberes docentes y enseñanza: la autorización de la palabra","resumen":"Este trabajo expone algunos hallazgos en una investigación referida a ?Prácticas pedagógicas y atención a la diversidad: el desarrollo de las competencias comunicativas en una población escolar de Nivel Inicial en contexto de pobreza? aprobada y subsidiada por el Instituto Nacional de Formación Docente (2008-09).  El objetivo general de la investigación estuvo dirigido a la identificación y el análisis de las concepciones y representaciones que orientan las prácticas pedagógicas de las maestras de nivel inicial respecto al desarrollo de las competencias comunicativas de sus alumnos. La implementación se hizo en una escuela pública ubicada en una zona periurbana de la capital tucumana, con   marcados índices de repitencia y deserción en todos los niveles.  Este artículo expone y analiza las prácticas pedagógicas que proponen las docentes con respecto al desarrollo del lenguaje, con el objetivo de explorar la  función que tiene la escuela en las prácticas lingüísticas y comunicativas de los  niños en el inicio de la escolaridad.   Con un enfoque metodológico cualitativo, se realizaron entrevistas a las docentes y se observaron clases y actividades dirigidas.   Los hallazgos muestran debilidades en ?el quehacer pedagógico-didáctico? en el acto dialógico que implica poner en juego la palabra , sostenerla y  visibilizar al ?otro? en sus? ?decires? .Recuperar la palabra y los saberes de los alumnos,   en el contexto de la clase para construir conocimientos que habiliten a trayectorias comunicativas potentes y sustentadas en discursos coherentes con posibilidades de complejizarse en saberes necesarios  hacia  la construcción de un  conocimiento cada vez más autónomo.","palabras_clave":"Competencias comunicativas|Educación Inicial|Prácticas docentes"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":54499,"idioma_id":5,"titulo":"LA CIUDAD INTERPELADA: PERCEPCIONES  DE SAN JUAN DE PUERTO RICO EN  EDUARDO LALO","resumen":"En el sugerente ensayo Pensar por islas, Frank Lestringant postula la existencia de un ?pensamiento geográfico del texto? donde la imagen del mundo informa la escritura literaria y en el cual el mapa precede a la ficción, condicionando en cierta manera su aparición, su organización y su lectura. Lestringant afirma que el espacio y más concretamente la topografía, es una forma del pensamiento. Estas líneas críticas me impulsaron a preguntarme y en consecuencia preguntarle a los textos del escritor puertorriqueño Eduardo Lalo, hasta qué punto el espacio insular caribeño cobra peso y forma en su escritura literaria, de qué manera(s) recorre alguno de sus motivos y tropos, cómo se configura el locus de enunciación de un escritor situado en una isla, cómo incide el particular estatuto de Puerto Rico en el mapa más amplio de América Latina. Por otra parte los textos de Lalo no solo dan cuenta de la isla sino que se localizan con particular énfasis en el espacio urbano; desde sus páginas pero también a partir de fotografías, grabados, instalaciones y videos, dado que es escritor pero también artista visual, emerge la ciudad de San Juan, consustanciada con los materiales y soportes que la conforman como ciudad « escrita », « mirada », « imaginada ». En este artículo procuro detenerme en una crónica temprana de Eduardo Lalo, En el Burger King de la calle San Francisco (1986), publicada luego en La isla silente (2002), para analizar la representación de la ciudad en  Los pies de San Juan (2002), crónica y libro objeto cuyas páginas albergan dibujos, caligrafías, tipografías, grabados y collages, cerrando el trabajo con algunas breves reflexiones en torno al último libro de Lalo, titulado Necrópolis (2014), que reúne poesía y dibujos. Procuramos volver visible una red textual entretejida a través de una sostenida reflexión sobre la ciudad y la isla, el desplazamiento y la condición de desarraigo del sujeto especialmente en el Caribe, la reflexión sostenida sobre materialidad misma de la escritura.","palabras_clave":"CIUDAD|ESPACIO|CARIBE|IDENTIDAD"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":55203,"idioma_id":4,"titulo":"On quadrupole and octupole gravitational radiation in the ANK formalism","resumen":"Following the approach of Adamo?Newman?Kozameh (ANK) we derive the equations of motion for the center of mass and intrinsic angular moment for isolated sources of gravitational waves in axially symmetric spacetimes. The original ANK formulation is generalized so that the angular momentum coincides with the Komar integral for a rotational Killing symmetry. This is done using the Winicour?Tamburino Linkages which yields the mass dipole-angular momentum tensor for the isolated sources. The ANK formalism then provides a complex worldline in a fiducial flat space to define the notions of center of mass and spin. The equations of motion are derived and then used to analyse a very simple astrophysical process where only quadrupole and octupole contributions are included. The results are then compared with those coming from the post newtonian approximation.","palabras_clave":"Gravitational Radiation|ANK Formalism"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":55662,"idioma_id":5,"titulo":"El léxico de la sexualidad en Filón de Alejandría: observaciones sobre la traducción","resumen":"El presente trabajo propone un análisis del vocabulario sobre sexualidad utilizado por Filón de Alejandría en su tratado Las leyes particulares 3 y una reflexión sobre los problemas que suscita la traducción de los términos de este campo léxico del griego helenístico a una lengua moderna como el español. Por un lado, el traductor debe enfrentarse a la dificultad de interpretar y hallar equivalentes en la lengua de llegada para conceptos que en la lengua de origen se expresan a través de eufemismos o procedimientos metafóricos. Por otro, existe el riesgo de introducir anacronismos o nociones foráneas al texto original en la traducción de vocablos referentes a un área de la vida social en que las diferencias culturales implican muchas veces conceptualizaciones de los comportamientos y prácticas aludidos absolutamente disímiles.","palabras_clave":"LÉXICO|SEXUALIDAD|FILÓN DE ALEJANDRÍA|TRADUCCIÓN"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":57992,"idioma_id":5,"titulo":"Los ríos de Homero: una mirada sofística de la 'paideia' en las 'Imágenes' de Filóstrato","resumen":"Las referencias explícitas e implícitas a Homero constituyen la influencia poética más importante en las Imágenes de Filóstrato el Viejo. Este trabajo ofrece un análisis del proceso creativo de la mímesis épica en tres ekfraseis de la colección, cuyo tema central son ríos de los relatos míticos. El estudio de los intertextos en las 'grafai' permitirá revelar cómo la segunda sofística construye una re-vision del poeta ciego a su imagen y semejanza: un Homero sofista.","palabras_clave":"EKFRASIS|HOMERO|FILOSTRATO|IMAGENES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":58364,"idioma_id":4,"titulo":"Analysing the cognitive effectiveness of the WebML visual notation","resumen":"WebML is a domain-speci&#64257;c language used todesign complex data-intensiveWeb applications at a concep-tual level. As WebML was devised to support design tasks,the need to de&#64257;ne a visual notation for the language wasidenti&#64257;ed from the very beginning. Each WebML elementis consequently associated with a separate graphical symbolwhich was mainly de&#64257;ned with the idea of providing sim-ple and expressive modelling artefacts rather than by adopt-ing a rigorous scienti&#64257;c approach. As a result, the graphicalmodels de&#64257;ned withWebML may sometimes prevent propercommunication fromtaking place between the various stake-holders. In fact, this is a common issue for most of the exist-ing model-based proposals that have emerged during the lastfew years under the umbrella of model-driven engineering.In order to illustrate this issue and foster in using a scienti&#64257;cbasis to design, evaluate, improve and compare visual nota-tions, this paper analysesWebML according to a set of solidprinciples, based on the theoretical and empirical evidenceconcerning the cognitive effectiveness of visual notations. As aresult,wehaveidenti&#64257;edasetofpossibleimprovements,some of which have been veri&#64257;ed by an empirical study.Furthermore, a number of &#64257;ndings, experiences and lessonslearnt on the assessment of visual notations are presented.","palabras_clave":"MODELLING|LENGUAGE|VISUAL|NOTATION"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":66383,"idioma_id":4,"titulo":"Congenital transmission of Trypanosoma cruzi in Argentina, Honduras, and Mexico: study protocol","resumen":"Compared with South America, there is a lack of epidemiologic studies about the risk of congenital transmission of Trypanosoma cruzi in Central America and Mexico. It has been suggested that T. cruzi genotypes might differ by region and that congenital transmission might vary according to the parasite´s genotype. Our objective was to compare T. cruzi congenital transmission rates in three countries. We performed an observational prospective study in 2011-2014 enrolling women at delivery in one hospital in Argentina, two hospitals in Honduras, and two hospitals in Mexico. Congenital T. cruzi infection was defined as the presence of one or more of the following criteria: presence of parasites in cord blood (direct parasitological microscopic examination) with positive polymerase chain reaction (PCR) in cord blood, presence of parasites in infant´s blood at 4-8 weeks (direct parasitological microscopic examination), and persistence of T. cruzi-specific antibodies at 10 months, as measured by at least two tests. Among 28,145 enrolled women, 347 had at least one antibody rapid test positive in cord blood and a positive enzyme-linked immunosorbent assay in maternal blood.PCRin maternal blood was positive in 73.2% of the cases, and genotyping identified a majority of non-TcI in the three countries. We found no (0.0%; 95% confidence interval [CI]: 0.0, 2.0) confirmed congenital case in Honduras. Congenital transmission was 6.6% (95% CI: 3.1, 12.2) in Argentina and 6.3% (95% CI: 0.8, 20.8) in Mexico. Trypanosoma cruzi non-TcI predominated and risks of congenital transmission were similar in Argentina and Mexico.","palabras_clave":"Trypanosoma cruzi|Chagas disease|Congenital transmission|Latin America"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":74900,"idioma_id":5,"titulo":"La convergencia de la historia y el psicoanálisis en Paul Ricoeur","resumen":"El tratamiento del psicoanálisis y la historia ha estado presente a lo largo de toda la obra de Ricoeur. Sin embargo, ambas temáticas han sido desarrolladas durante largo tiempo por caminos paralelos. En la década de los ochenta se observan acercamientos desde su interpretación del psicoanálisis hacia la historia. Por su parte, la historia adquiere un giro psicoanalítico en La memoria, la historia, el olvido. Nuestra hipótesis es que Ricoeur debió modificar su concepción de historia y de psicoanálisis para lograr este proceso de convergencia. Para decirlo brevemente, el psicoanálisis se tuvo que ?historizar?, y la historia que ?patologizar?.","palabras_clave":"inconsciente|narración|imaginación|pulsiones"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":83618,"idioma_id":4,"titulo":"Three New Thiosaccharin Derivatives Generated in a Complex Reaction System","resumen":"The reaction between thiosaccharin and ethylamine showed to be relatively complex. The main product of this reaction is 3-ethylamino-1,2-benzisothiazole 1,1-dioxide (1), which could be clearly identified by NMR and IR spectroscopies. Ethylammonium thiosaccharinate (2) and 3-vinylamino-1,2-benzisothiazole 1,1 dioxide (3) were generated as minor by products during this reaction and their structures weredetermined by X-ray diffraction methods. The (2) salt crystallizes in the monoclinic P21\/c space group with a=13.1367(5), b=9.9721(4), c=8.8217(3) Å, &#946;=99.125(4)°, and Z=4, whereas compound (3) belongs to the P21\/m space group with a=7.1572(5), b=7.0242(7), c=9.5503(8) Å, &#946;=95.008(7)°, and Z=2.","palabras_clave":"Thiosaccharin\/ethylamine reaction|3-ethylamino-1,2-benzisothiazole 1,1 dioxide;|ethylammonium thiosaccharinate|3-vinylamino-1,2-benzisothiazole 1,1 dioxide|Crystal structures"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":86114,"idioma_id":5,"titulo":"Doctrina","resumen":"SE ANALIZA EL REGIMEN JURIDICO DE UN SITIO WEB. CON SU IDENTIFICACION Y CONTENIDOS. ASI COMO LAS RESPONABILIDADES CIVILES DERIVADAS DE INTERNET","palabras_clave":"Capacidad|Ancianidad|Restricciones|Reconocimiento"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":88445,"idioma_id":4,"titulo":"Environmental effects of ozone depletion and its interactions with climate change: progress report, 2011","resumen":"The Parties to the Montreal Protocol are informed by three Panels of experts. One of these is the Environmental Effects Assessment Panel (EEAP), which deals with two focal issues. The first focus is the effects of UV radiation on human health, animals, plants, biogeochemistry, air quality, and materials. The second focus is on interactions between UV radiation and global climate change and how these may affect humans and the environment. When considering the effects of climate change, it has become clear that processes resulting in changes in stratospheric ozone are more complex than previously believed. As a result of this, human health and environmental issues will be longer-lasting and more regionally variable. Like the other Panels, the EEAP produces a detailed report every four years; the most recent was published as a series of seven papers in 2015 (Photochem. Photobiol. Sci., 2015, 14, 1-184). In the years in between, the EEAP produces less detailed and shorter Progress Reports of the relevant scientific findings. The most recent of these was for 2015 (Photochem. Photobiol. Sci., 2016, 15, 141-147). The present Progress Report for 2016 assesses some of the highlights and new insights with regard to the interactive nature of the direct and indirect effects of UV radiation, atmospheric processes, and climate change. The more detailed Quadrennial Assessment will be made available in 2018.","palabras_clave":"CLIMATE CHANGE|UVR"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":91216,"idioma_id":4,"titulo":"First Report of Sweet potato leaf curl virus infecting sweet potato in Argentina","resumen":"iruses of the genus Begomovirus (family Geminiviridae) have circular single-stranded DNA genomes composed of one or two components. They are transmitted by the whitefly Bemisia tabaci (Hemiptera: Aleyrodidae) and are agents of important diseases in dicotyledonous crops worldwide (Navas-Castillo et al. 2011). The sweepoviruses constitute a monophyletic group of monopartite begomoviruses that infects sweet potato (Ipomoea batatas) and other species of the family Convolvulaceae. Sweet potato is an important vegetable crop and is widely cultivated and consumed in Argentina. Leaf curl disease was first reported in the country in 2012 (Rodríguez-Pardina et al. 2012) associated with an increase of whitefly populations. In September 2014, random samplings of more than 100 plants showing upward leaf curling and mild vein clearing symptoms were conducted in eight sweet potato plots in Colonia Molina, Mendoza Province, Argentina (32.8316311°S, 68.7238142°W). The presence of begomovirus was suggested by PCR using degenerate primers SPG1 and SPG2 that amplified a 912-bp fragment from a conserved region in open reading frames C2 and C1 (Li et al. 2004). Total DNA from three samples was used as a template for rolling circle amplification (RCA) and viral DNA enrichment (Inoue-Nagata et al. 2004). RCA products were pooled and submitted to deep sequencing in an Illumina MiSeq system. Sequencing analysis showed one contig corresponding to the full-length genome of Sweet potato leaf curl Georgia virus (SPLCGV) with coverage of over 40,000 reads. Overlapping primers were designed based on the contig sequence to recover the full-length viral DNA genome. The expected size &#8764;2.8-kb fragment was amplified from one of the samples and was cloned into the TOPO TA 2.1 and sequenced. The obtained sequence had the genome structure characteristic of a sweepovirus. Species demarcation tool (SDT) analysis showed the highest nucleotide sequence identity (92%) with an SPLCGV isolate from Cuba (KC253236) and identities ranging from 90 to 91% with other SPLCGV isolates from China and the United States. The obtained sequence had 83.5% sequence identity with the Sweet potato leaf curl virus (SPLCV) isolate from Argentina (Rodríguez-Pardina et al. 2012). In accordance with the current taxonomic criteria for begomovirus classification (Brown et al. 2015), this begomovirus isolate from sweet potato in Argentina represents a new strain of SPLCGV, which was named SPLCGV- [AR-MDZ] (KX611145). This is the first report of SPLCGV in Argentina, and our findings expand the geographical distribution of this begomovirus that to date had been reported in the United States, China, and Cuba.","palabras_clave":"Ipomoea batatas  |Geminivirus|Begomovirus|sequence"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":101764,"idioma_id":5,"titulo":"La noción de comunidad en Heidegger y su recepción en la filosofía francesa","resumen":"El trabajo aborda la noción de comunidad en Heidegger en sus escritos y discursos del período del Rectorado en Friburgo (1933\/34) y la compara con la perspectiva francesa (Bataille, Blanchot, Derrida, Nancy) en torno al debate contemporáneo sobre la comunidad. A propósito se analizan en detalle las nociones heideggerianas que estos pensadores trabajan, para distinguir qué aspectos de éstas retoman y cuáles rechazan. Con esto, el trabajo sostiene que esta comparación permite elaborar una reflexión sobre la tensión inherente a la noción de comunidad y, de este modo, descubrir por qué esta tensión es parte de su naturaleza.","palabras_clave":"Heidegger|comunidad|interpretación francesa"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":104664,"idioma_id":5,"titulo":"Ampliando el concepto de ética y responsabilidad social empresaria","resumen":"El Documento ?La vocación del empresario: una reflexión? elaborado por el Consejo Pontificio para la Justicia y la Paz recoge la preocupación existente en las últimas décadas por la ética y la responsabilidad social empresarias pero ampliando y profundizando su alcance. El auge de éstas últimas tuvo su causa, al menos en el discurso, en el avance en nuestra sociedad de tres opiniones cada vez más generalizadas. La primera es la toma de conciencia del enorme costo que representan, en términos sociales, ambientales y humanos, los efectos colaterales o, como los denominan los economistas, las externalidades negativas de nuestras acciones económicas y empresariales. La segunda es el redescubrimiento del factor humano en la economía y la empresa que ha aumentado enormemente la expectativa acerca de la necesidad de una rendición de cuentas por parte de los responsables de las empresas.La tercera es la necesidad creciente que se experimenta de contrarrestar la fragmentación y separación existente entre los distintos ámbitos económico, político, social, tecnológico de la cultura y de integrarlos entre sí y con los fines esenciales de la vida (Koslowski, 2001: 4-7).","palabras_clave":"ETICA|RSE|EMPRESA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":116693,"idioma_id":5,"titulo":"PROLOGO","resumen":"Como arqueólogos, en el transcurso de nuestras investigaciones solemos encontrarnos con problemas cuya resolución puede demorarse o, directamente, no lograr ser alcanzada. Ello se debe a que el registro material con el que trabajamos, por definición, es fragmentario o incompleto. El estudio de las tecnologías originarias es un campo en el que despejar determinadas incógnitas puede llevar años de investigación, de pruebas, de consultas y de trabajo interdisciplinario y en equipo. Estos trayectos, muchas veces truncos, suelen estar ausentes en las presentaciones en encuentros científicos y en las publicaciones periódicas de los resultados obtenidos. Ello se debe principalmente a que en dichos espacios convencionales de exposición y divulgación científica se privilegian las metodologías y las conclusiones que dealguna manera ?llegan a buen puerto? o, en su defecto, la agenda de trabajos futuros que proyectan la evaluación de aspectos no esclarecidos durante la investigación. Es decir, en los mencionados ámbitos usualmente se enfatiza sobre aquellos aspectos que se muestran confiables y arrojan resultados acordes con los estándares científicos. De esta manera, los esfuerzos infructuosos, los errores, las dudas no resueltas, las posibilidades abandonadas, las incertidumbres que aún quedan pendientes y demás elementos del día a día del quehacer científico quedan fuera de la discusión o simplemente se invisibilizan.En función de lo expresado y en el marco de la configuración del Ciclo de Talleres de la División Arqueología del Museo de La Plata, se planteó la posibilidad de conformar un espacio en el que se puedan discutir los aspectos problemáticos y poco visibles de nuestras investigaciones; por así decirlo, el ?detrás de escena? de las mismas. Justamente, la modalidad de taller permite la generación y el intercambio de ideas a la vez que los asistentes ponen a prueba diferentes modos de resolución de interrogantes, lo que fomenta la diversidad deopiniones y el desarrollo de vías alternativas de abordaje. En este sentido, el presente encuentro tiene como objetivo establecer un espacio en el que los equipos de investigación de la División Arqueología, en particular, y de la Facultad de Ciencias Naturales y Museo, en general, expongan las situaciones problemáticas a las que se enfrentan\/ron en el estudio de diferentesaspectos de las tecnologías líticas prehistóricas. Se invita a que detallen los aciertos, errores y dudas en sus estudios, así como los resultados (parciales o concluyentes) a los que han arribado, con el fin de compartir aquellas experiencias tradicionalmente ?no publicables? y fomentar debates en los que las ideas ajenas puedan enriquecer las investigaciones propias y, por otra parte, conocer en qué aspectos están trabajando otros equipos.","palabras_clave":"HISTORIA|CIUDAD|CATEGORIAS|ARQUITECTURA"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":117213,"idioma_id":5,"titulo":"Reseña","resumen":"Gentile selecciona para su publicación dos fuentes documentales de gran valor para analizar la participación de los jesuitas en el escenario de las relaciones hispano-calchaquíes de mediados del siglo XVII. Cabe señalar que al día de hoy se puede acceder a los originales de ambas fuentes, a través de la página web de la Biblioteca Nacional de Brasil en la sección Manuscritos. Estos documentos se suman a un número importante de fuentes pertenecientes a la provincia jesuítica del Paraguay colectados en nuestro país por Pedro de Angelis y vendida al Brasil en 1853.","palabras_clave":"historia|clase|trabajadora|argentina"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":118923,"idioma_id":5,"titulo":"Actualidad en Derecho Penal","resumen":"Compendio de jurisprudencia Penal y Procesal Penal de la provincia de Buenos Aires.","palabras_clave":"ACTUALIDAD|DERECHO|DAÑOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":121334,"idioma_id":5,"titulo":"Cultura, Sociedad vida cotidiana y política durante el estalinismo: nuevos aportes de investigación","resumen":"En los últimos años, se ha verificado una gran apertura y renovación en los estudios de la Rusia soviética. Presentamos en este trabajo un debate historiográfico acerca de una serie de estudios provenientes mayormente de la historiografía anglosajona de las últimas décadas que siguieron a la caída de la Unión Soviética con la intención de entender el sistema de valores, las prácticas culturales y la sociedad que se fue forjando en la Unión Soviética bajo los años de la revolución de Stalin. Se trata de una sociedad que estuvo signada por las profundas transformaciones económicas impuestas a través de los planes quinquenales, las persecuciones políticas y el intento -no sin contradicciones- de poner en marcha un hombre nuevo, imbuido de los valores soviéticos. El estalinismo supuso una enorme transformación para la Rusia todavía predominantemente campesina que había hecho la revolución de 1917. La profundidad de esta transformación revolucionaria no sólo se advierte en las formas de producción y de gobierno, sino en la vida cotidiana, la sociedad, la cultura, los valores y las costumbres de todo un pueblo. Son estas precisamente las aristas que más han contribuido a iluminar los estudios que aquí presentaremos.","palabras_clave":"Estalinismo|historiografía|vida cotidiana|totalitarismos"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":123924,"idioma_id":5,"titulo":"Leer y escribir en las Ciencias Sociales en universidades argentinas","resumen":"Este trabajo explora los puntos de vista de docentes y alumnos universitarios sobre la escritura y lectura involucradas en el estudio de las Ciencias Sociales. Los datos fueron recogidos predominantemente a través de entrevistas, complementadas con grupos focales. Los resultados muestran que leer y escribir son requerimientos ubicuos en las materias estudiadas pero suelen pasar inadvertidos: no aparecen mencionados en los programas de cátedra, y resultan escasamente orientados por los docentes ya que se dan por sabidos. Sin embargo, los entrevistados revelan que la lectura y escritura requeridas en estas materias son prácticas novedosas y desafiantes para los alumnos porque difieren de los modos de leer y escribir ejercitados en la escuela secundaria. A pesar de que los problemas de los alumnos son reconocidos, los docentes no suelen ocuparse de cómo leen y escriben sus estudiantes por limitaciones institucionales y por considerarlo impropio de su función en base a ciertos supuestos, cuestionados por las investigaciones. Estos resultados son relevantes para la discusión de políticas institucionales atinentes a quiénes cabe la responsabilidad de ayudar a participar en las prácticas de estudio que la universidad demanda. La respuesta debería considerar también el cómo y el porqué. http:\/\/revistas.udistrital.edu.co\/ojs\/index.php\/enunc\/article\/view\/12350DESCARGAR. http:\/\/revistas.udistrital.edu.co\/ojs\/index.php\/enunc\/article\/download\/12350\/12884","palabras_clave":"enseñanza|universidad|escritura|lectura"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":135990,"idioma_id":4,"titulo":"The Relationship between Parental Variables, Empathy and Prosocial-Flow with","resumen":"The goal of this study was to explore the relationship between two different aspects ofthe parent-child relationship (parental challenge and authoritative parental style) andempathy as well as prosocial flow with prosocial behavior toward strangers, friends,and family. The participants were 422 young adults who were enrolled inundergraduate social responsibility courses at a University. The results show that thecombination of parental support and parental challenge has an important influence onprosocial flow and on positive behavior such as prosocial behavior toward friends andfamily, but no influence on that toward strangers. Moreover, in the same way, empathyand prosocial flow promote prosocial behavior toward these three targets. Theinterpretations of these findings are delineated in the discussion.","palabras_clave":"EMPHATY|PROSOCIAL FLOW|AUTHORITATIVE PARENTAL STYLE|PARENTAL CHALLENGE|PROSOCIAL BEHAVIOR"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":136052,"idioma_id":5,"titulo":"Transformaciones recientes en el proceso de trabajo y en la acumulación de capital en la producción agraria argentina","resumen":"En este artículo se realiza un análisis de las transformaciones recientes en la producción material y en la acumulación de capital en la producción agraria argentina. Con base en una variedad de fuentes estadísticas, se muestra que el cultivo genéticamente modificado ha hegemonizado esta producción permitiendo la aparición de nuevas economías de escala. Luego, se presentan algunos estudios de casos representativos que muestran que esta transformación no alcanzó para superar las barreras de entrada que históricamente encontraron los capitales más concentrados de la economía nacional en este sector. Esta última conclusión desafía a varias concepciones dominantes en la literatura especializada.","palabras_clave":"PRODUCCION AGRARIA ARGENTINA|PROCESO DE TRABAJO AGRARIO|CAPITAL AGRARIO|AGRIBUSINESS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":136085,"idioma_id":5,"titulo":"Evaluación radiográfica de la erupción dentaria permanente en individuos de 4 a 14 años","resumen":"SE EVALUARA SOBRE RADIOGRAFi&#769;AS PANORAMICAS LA ERUPCION DELAS PIEZAS DENTARIAS PERMANENTES EN UNA POBLACIo&#769;N DE LA CIUDAD DE LA PLATA. EL RANGO DEEDAD CONSIDERADO SERA DE ENTRE 4 Y 14 An&#771;OS.EL TAMAn&#771;O DE LA MUESTRA SERA DE 300 UNIDADES EXPERIMENTALES, CONSIDERANDO COMO TAL A CADA RADIOGRAFi&#769;A PANORa&#769;MICA","palabras_clave":"PANORAMICA|HEREDITARIOS|PIEZAS DENTARIAS|NIÑOS"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":136148,"idioma_id":4,"titulo":"Antioxidant properties of Calendula officinalis L. (Asteraceae) on Fe2+-initiated peroxidation of rat brain mitochondria","resumen":"In the study reported here, the effect of Calendula officinalis L. (Asteraceae) extract (CO) on the polyunsaturated fatty acid composition, chemiluminescence, and Peroxidizability Index (PI) of mitochondria isolated from brain rat was analyzed. After incubation of mitochondria in an ascorbate (0.4&#8201;mM)-Fe++ (2.15&#8201;µM) system (180&#8201;min at 37&#8201;°C), it was observed that the total cpm\/mg protein originated from light emission: chemiluminescence was lower in brain mitochondria obtained from CO group than in the control group (without extract supplementation). Moreover, it was observed that the extract was reduced, concentration dependent, of chemiluminescence, measured as total cpm. The fatty acid composition of brain mitochondria from control group was profoundly modified when subjected to non-enzymatic lipoperoxidation with a considerable decrease of arachidonic acid C20:4&#969;6 and docosahexaenoic acid C22:6&#969;3. As consequence, the PI, a parameter based on the maximal rate of oxidation of specific fatty acids was higher in the CO group than in the control group. The simultaneous analysis of PI, chemiluminescence, and fatty acid composition indicates that CO may act as an antioxidant protecting rat brain mitochondria from peroxidative damage.","palabras_clave":"Antioxidant|Calendula officinalis|rat brain mitochondria"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":136197,"idioma_id":5,"titulo":"Evaluación de FAMACHA© en el control de nematodes gastrointestinales en cabras de San Luis (Argentina)","resumen":"Evaluación de FAMACHA© en el control de nematodes gastrointestinales en cabras de San Luis (Argentina)RESUMENDentro de las enfermedades que ocasionan  un  gran  deterioro  en la  producción  caprina,  las parasitosis por los nematodes gastrointestinales tienen  una importancia   preponderante, especialmente  las  producidas por Haemonchus contortus,  especie dominante en  el centro de la Argentina y de mayor significación por las pérdidas que ocasiona. Con el objetivo de evaluar el sistema de control FAMACHA© (FAM) en la detección de anemia en cabras de San Luis (Argentina), se muestrearon 42 animales en un establecimiento de producción de cabritos ubicado en Villa Mercedes (SL). Durante los meses estivales se determinó el color de la mucosa ocular según la escala de la carta de colores FAM con cinco grados, el hematocrito (Hem), la condición corporal (CC), el conteo de huevos (hpg) y las especies de nematodos presentes. Las  observaciones se realizaron sobre dos grupos de 21 animales: el G1 sin desparasitar al comienzo del ensayo y el G2 desparasitado al comienzo de la estación estival (manejo del establecimiento) con Ricobendazol al 15 % ajustada a dosis caprina. Los animales con los grados FAM 4 y 5 fueron desparasitados con la misma droga y dosis. Se estimó la correlación existente entre los grados de  FAM, Hem y CC, como la sensibilidad (S), especificidad (E) y los valores predictivos positivo (VP+) y negativo (VP-) usando el Hem &#8804;19% para determinar anemia. Los coprocultivos demostraron un predominio de Haemonchus superior al 64% promedio del período. Los grados de FAM 2 y 3 fueron los más numerosos y con hematocritos más alto que los de la bibliografía, mientras que los grados 4 y 5 se encontraron dentro de los parámetros de hematocritos anémicos. Los coeficientes de correlación (p&lt;0,01) fueron: entre Hem-FAM r= - 0,56 y r= - 0,50, entre  el hpg-FAM y r= 0,46 y r= 0,29 y entre CC- FAM  r= - 0,53 y r= - 0,35 respectivamente para G1y G2.  La S en ambos grupos fue mayor (100%) cuando se usaron los criterios FAM 3, 4 y 5 como positivos, sin embargo la E de ambos grupos fue mayor (93% y 99% respectivamente) para los criterios positivos de 4 y 5. En ambos grupos, el VP- siempre fue alto (&gt; a 99,2%) demostrando seguridad al diagnosticar a los verdaderos negativos. Por el contrario el VP+ fue bajo al considerar positivos los valores 3, 4 y 5 seguramente debido al alto porcentaje de falsos positivos, pero mediano al considerar positivos los valores 4 y 5. Al final del estudio se observó la misma carga de hpg entre los grupos, a pesar que G1 utilizó un 41% menos de antihelmíntico respecto a G2. El uso de FAMACHA© en caprinos constituye una herramienta de gran utilidad para el control de la haemoncosis, ya que permite detectar y desparasitar a los animales del rebaño que se manifiestan como más sensibles a los Haemonchus (Tratamientos selectivos). Palabras clave: Haemonchus contortus,  anemia, control por color de la conjuntiva ocular, tratamientos selectivos.","palabras_clave":"Haemonchus contortus|anemia |control por color de la conjuntiva ocular|tratamientos selectivos"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":136286,"idioma_id":5,"titulo":"Adaptación Argentina de la Escala de Ambiente Invalidante Infantil (ICES-A)","resumen":"El ambiente invalidante es un concepto central del Modelo Biosocial de Marsha Linehan (1993).La Escala de Ambiente Invalidante Infantil (ICES) es un cuestionario diseñado específicamente paraevaluar este constructo de manera retrospectiva. Se presenta la adaptación al español de esta es-cala, junto con datos sobre las cualidades psicométricas del instrumento. La escala exhibió unabuena consistencia interna. Según el análisis factorial exploratorio, mostró una estructura de dosfactores, diferenciando los ítems relacionados con la reacción negativa del padre hacia la expresiónemocional del niño, de los que reflejan la respuesta de apoyo de los padres hacia el niño. Estos pri-meros ensayos muestran que esta adaptación del ICES es una prueba adecuada para evaluar el am-biente invalidante infantil en sujetos de habla hispana.","palabras_clave":"Ambiente Invalidante|Teoría Biosocial|Trastorno Límite de la  Personalidad"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":136456,"idioma_id":5,"titulo":"Investigaciones arqueológicas en el sitio Alero Dupuy, provincia de San Luis","resumen":"Completar","palabras_clave":"ARQUEOLOGIA|SAN LUIS|ALERO DUPUY|CAZADORES RECOLECTORES"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":136811,"idioma_id":5,"titulo":"'Malentretenidos, puñales y besos. Sobre algunas escenas homoeróticas en la tradición gauchesca'","resumen":"    Según  Nicolás Rosa, 'la tenebrosa sexualidad del gaucho' sólo puede recomponerse en  los límites temerarios de lo decible. Efectivamente, generando fricciones entre  lo sancionado y la transgresión, la sugerencia y lo explícito, la tradición  gauchesca fue articulando numerosas representaciones sobre una homoerótica  propia del género. Este trabajo propone un recorrido desde las afectividades  veladas de Martín Fierro y las  parejas gauchas de Eduardo Gutiérrez, hasta la homofobia de Juan Filloy y el  exhibicionismo de Néstor Perlongher, tratando de discernir cómo estas  representaciones postulan deconstrucciones de los tópicos del género (la  virilidad, la amistad, etc.) desde el ocultamiento, la hipérbole o la parodia.  ","palabras_clave":"LITERATURA ARGENTINA|TRADICIÓN GAUCHESCA|HOMOEROTISMO|INTERTEXTUALIDAD"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":139791,"idioma_id":5,"titulo":"Identidades políticas y perspectiva regional. En torno a la irrupción del  fenómeno peronista en Argentina","resumen":"La intención del presente artículo es contribuir a la reflexión en torno  a la dimensión sociocultural de los procesos políticos y a la complejidad de  los factores implicados en los fenómenos de conformación y redefinición de  identidades. A un nivel específico el eje del interés pasa por analizar la  naturaleza del lazo político que vinculó a los habitantes de las tierras  altas de Jujuy (Argentina) con el peronismo, identificando para ello los  diversos contextos que gravitaron sobre los procesos de configuración de los  sentidos que informaron sus acciones y decisiones políticas. Entre estas  realidades contextuales, se focaliza la atención en la tradición política  reivindicativa en torno a la cuestión agraria y en la gravitación de un  liderazgo local.","palabras_clave":"HISTORIOGRAFÍA ARGENTINA|PERSPECTIVA REGIONAL|FENÓMENO PERONISTA|IDENTIDADES POLÍTICAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":139829,"idioma_id":5,"titulo":"Una ofrenda como acto fundacional de estructuras de cultivo. Primer milenio de la era en el valle de Tafí (Provincia de Tucumán, Argentina)","resumen":"El estudio sistemático del paisaje agrario en el valle de Tafí ha permitido reconocer numerosas prácticas vinculadas al ciclo agrícola y doméstico. En esta oportunidad se analiza un depósito arqueológico registrado en una estructura para el cultivo emplazada en el sitio arqueológico La Bolsa 1, un asentamiento aldeano ocupado principalmente entre el 200 a.C y el 800 d.C. Los análisis arqueológicos realizados permiten proponer que el conjunto fue generado por prácticas rituales que, de acuerdo a referencias etnográficas y arqueológicas del área andina, se habrían destinado a la búsqueda de fertilidad y buenas cosechas.","palabras_clave":"OFRENDA|AGRICULTURA|PRIMER MILENIO|ARQUEOLOGÍA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":140504,"idioma_id":4,"titulo":"Pilcomayo River Basin - International Hydraulic Challenges","resumen":"The Pilcomayo river basin raises the three countries that share (Argentina, Bolivia and Paraguay) a huge challenge in various aspects such as social (more than 20 ethnic groups living in the basin), economic (demand is high and is located away of the major economic centers in each country), environmental (in the upper basin mining and oil-gas activities are intense for centuries, in the middle basin the river has a high mobility and sediment transport of the highest in the region and in the lower basin its singular nature of interrupt-stream leads to various wetlands with high biodiversity). A compilation and analysis of major hydraulic problems encountered in the basin are presented in this chapter. These are the high mobility of the channel, the possibility of changing course during floods and high difficulties in the distribution of water and sediment between Argentina and Paraguay.","palabras_clave":"Pilcomayo river basin|fluvial hydraulic challenges|water and sediment distribution|channel mobility"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":140559,"idioma_id":4,"titulo":"Effect of climatic seasonality and food availability on the activity budget and the diet of black and gold howler monkeys (Alouatta caraya)","resumen":"Abstract. The activity budget and the diet of primates are influenced by climatic seasonality and daylength. Here, we examined the effect of seasonality and food availability on the activity budget anddiet of black and gold howler monkeys (Alouatta caraya). These monkeys are living near the southernlimit of their geographic distribution in a subtropical environment, near a transitional limit to beinga warm and temperate climate. Their habitat is characterized by seasonal fluctuations in temperatureand day length. In the winter months, days are colder and about three hours shorter than inthe summer. Fall and spring are intermediate in terms of temperatures and day length. There was amarked seasonality in resource availability, mainly in seasonal foods: new leaves, flowers, and fruits.Non-seasonal foods, mostly mature leaves, were less variable and more abundant throughout theyear. The monkeys´ activity budget and diet composition differed between seasons. Their time spentresting was highest in the summer and lowest in the spring. Their time spent moving and engagingin social activities was highest in the spring, the season with the greatest availability of seasonal foods.Temperature had no influence on their activity budget. There was a negative relationship betweenthe abundance of non-seasonal foods and time spent feeding, and also between the abundance ofseasonal foods and time spent resting. The abundance of seasonal foods positively correlated withtime spent moving and engaging in social activities. During the spring, their diet was dominated bynew leaves. In the summer and early fall, their diet consisted mainly of mature leaves and fruits. Ourresults indicate that seasonality influences both the activity budget and diet of Alouatta caraya livingnear the southern limit of their distribution. The periods of time with low availability or absence ofseasonal foods may be the key variable in determining the limits for primate geographic distributiontowards the southern latitudes.","palabras_clave":"ACTIVITY PATTERN|ALOUATTA CARAYA|TEMPERATE CLIMATE|FOOD AVAILABILITY"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":140665,"idioma_id":5,"titulo":"Conocimientos en intersección: regulaciones estatales y experiencias formativas cotidianas, escolares y comunitarias, en grupos indígenas de Argentina.","resumen":"En este capítulo, nos proponemos abordar las experiencias formativas cotidianas de niños y niñas indígenas de dos colectivos étnicos de Argentina, qom y mbyà, producidas tanto en contextos escolares como a través de su participación en otros espacios sociales. Las principales y más recientes políticas educativas destinadas a los pueblos indígenas en Argentina están enmarcadas en la Modalidad de Educación Intercultural Bilingüe (EIB), establecida en 2006 y reconocida como derecho en la Constitución Nacional desde el año 1994. La normativa que regula estas políticas es de carácter general y, en consecuencia, comprende a todas las escuelas donde asisten niños indígenas; es decir que su aplicación debería ser independiente del número de alumnos, tipo de gestión, nivel o contexto. Sin embargo, el trabajo de campo con población qom y mbyà nos permite mostrar cómo las instituciones se inscriben en forma variable en la modalidad de EIB, resultando la experiencia escolar de los niños y niñas indígenas altamente heterogénea. Los rasgos principales de variación son la presencia de docentes o auxiliares indígenas, el uso de la lengua propia en la alfabetización, la inclusión de contenidos culturales particulares en el curriculum y las formas de enseñanza.","palabras_clave":"Conocimientos|Regulaciones|Experiencias formativas|Grupos indígenas"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":140812,"idioma_id":4,"titulo":"Spanish discovers Yiddish (or the cultural policies of Salomón Resnick in Argentina in the Interwar period)","resumen":"Solomon Resnick (Russia, 1894-Argentina, 1946) was, and remains to this day, one of the most important facilitators of the encounter between two linguistic and cultural worlds that rarely met before him: Spanish and Yiddish. His historical significance as a cultural mediator can be measured in the variety and number of intellectual tasks that he carried out as well as in his being one of the first to perceive the need to foster this contact.  For him and for the handful of intellectuals and cultural entrepreneurs that propelled similar actions, it was about presenting a yet unknown literary and intellectual repertoire to the new country of arrival, Argentina, and through it to the whole geography of Spanish speakers. His work, which can be read as an extended political-cultural project that unfolded throughout his life, developed through different actions. First, translation itself. This is, the passage of essays as well as political and literary texts from Yiddish into Spanish. His successive selections and translations appeared in various newspapers, magazines and books. In addition to these translations, he published a large number of notes, prologues, short articles, etc., where he sought to present to Spanish-speaking readers the names, styles, concerns, traditions, movements and transformations of Jewish culture in general and Yiddish in particular. Third, Resnick stands out among his contemporaries for the creation and support of publishing projects of great importance. On the one hand, he participated in a number of periodicals, of which the most important were the daily Mundo Israelita (co-founded by Resnick in 1923 and co-directed by him in its first ten years) and the journal Judaica (created in 1933 and directed by him until his death in 1946). On the other hand, he was a constant promoter of the publication of books, mostly produced in not entirely favorable conditions. The fact that all of these publications were not under one imprint has made it difficult to recognize this aspect of his work as a cultural mediator. The first four decades of the twentieth century, the period during which he developed his intellectual work, were the heyday of literary, intellectual and political creation in Yiddish in the world. But these were also the decades, especially the 1930s, where migrations, ideological disputes within the Jewish world and the growing anti-Semitic persecution in Europe, presaged  serious threats to the survival of this language.","palabras_clave":"YIDDISH LANGUAGE|ARGENTINE JEWISH HISTORY |TRANSLATION|PUBLISHING"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":140813,"idioma_id":4,"titulo":"Biodegradable Composites Based on Thermoplastic Starch and Talc Nanoparticles","resumen":"Nowadays, technological interest is focused on a new generation of compositespolymers based on biodegradable matrixes from renewable raw materials with organic or mineral fillers. These biocomposites have several advantages mainly due to their ecofriendly character since they can be naturally degraded plus their renewable origin.Thus, starch is a good candidate because of its availability, biodegradability, and low cost. Naturally, starch is not considered as a thermoplastic polymer but, when is compounding with a plasticizers, under high temperature and shear stresses, allows the disruption of its granular structure, becoming into thermoplastic starch (TPS). Main disadvantages of TPS materials are related to their poor mechanical properties and moisture absorption. Addition of natural fillers or mineral particles to improve their final properties is an interesting alternative. In this sense, talc particles can be used to reinforce starch matrixes mainly due to its laminar morphology, as well as, its nanometric size thickness. The aim of this chapter comprises the development of starchbased composites with talc nanoparticles. Well dispersed and distributed nanoparticles in TPS matrix is obtained by direct melt mixing. Final TPS properties result improved.These results are interpreted in terms of an accurate analysis of the processingproperties- structure relationship","palabras_clave":"BIOCOMPOSITES |THERMOPLASTIC STARCH|TALC NANOPARTICLES|PROCESSING|MICROSTRUCTURE|FINAL PROPERTIES|APPLICATIONS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":140822,"idioma_id":5,"titulo":"¿Niños pobres? ¿Niños ricos? Discusiones sobre las representaciones y regulaciones de la vida familiar en torno a la escolaridad infantil","resumen":"Este artículo se centra en los modos de representar y regular las relaciones entre las familias y las escuelas en pos del desarrollo de la escolaridad infantil, considerando las similitudes y diferencias que se producen según la clase social de pertenencia de los niños. Surge de dos investigaciones etnográficas que abordaron estas relaciones a partir del trabajo con sujetos pertenecientes a la 'clase alta', por un lado, y a los sectores subalternos, por otro. Los referentes empíricos sobre los que nos basamos refieren al trabajo de campo realizado a partir de entrevistas y observación participante en contextos escolares y en el ámbito doméstico, con adultos con niños a su cargo (incluyendo padres, madres, otros parientes, docentes, etc.) en el área metropolitana de la Ciudad de Buenos Aires. El análisis incorpora también fuentes producidas por organismos internacionales (tales como UNESCO y UNICEF), de organismos nacionales (políticas y legislación de diferentes niveles jurisdiccionales), y de la literatura académica y de divulgación destinada a la regulación de estas relaciones en diversos momentos históricos.El objetivo específico es documentar algunas regulaciones hegemónicas contemporáneas en cuanto a las obligaciones y responsabilidades en torno a la escolaridad de los niños, y a las representaciones sociales que se articulan con las mismas. Se trata de indicaciones que establecen la necesidad de predisposiciones afectivas y acciones específicas por parte de las familias de los niños (más concretamente, de los padres), como condiciones previas y simultáneas al desarrollo de la escolarización infantil. En estas regulaciones subyacen representaciones profundamente ancladas en la contemporaneidad sobre las formas en que debe organizarse y configurarse lavida familiar para garantizar el desarrollo educativo infantil. Estas orientaciones tienden a establecer relaciones lineales entre las acciones adultas y sus efectos en los niños, y entre los resultados de escolarización infantil y las posibilidades de movilidad social de los mismos.Al basarnos en lo registrado en contextos atravesados de forma antagónica por los procesos dedesigualdad social, se realiza un análisis comparativo de los modos en que estas regulaciones y representaciones generan apelaciones diferenciales según la clase social a la que estén dirigidos, al tiempo que pivotan sobre concepciones de infancia genéricas, alejadas de las experiencias cotidianas relevadas. Se ponen en primer plano los procesos de desigualdad que resultan velados en estas producciones hegemónicas, en su tendencia a desplazar las causas de la desigualdad social hacia los procesos educativos y hacia los adultos vinculados de forma inmediata a la cotidianeidad de los niños.","palabras_clave":"NIÑOS|CLASES SOCIALES|REPRESENTACIONES Y REGULACIONES SOBRE LA VIDA FAMILIAR|ESCOLARIDAD INFANTIL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":140847,"idioma_id":5,"titulo":"ENDERMEDAD Y CURA EN EUMÉNIDES DE ESQUILO. ORESTES, LAS ERINIAS Y LA PÓLIS?","resumen":"El presente trabajo analiza la relación entre la enfermedad como fenómeno individual y sus consecuencias amplias en el cuerpo de la pólis. Partiendo de la locura como caso testigo, se plantea la hipótesis según la cual los tratados médicos, específicamente el Corpus Hippocraticum, se centran en una perspectiva individual de la enfermedad sin considerar los efectos que el accionar del enfermo pueda causar en su ciudad. La tragedia, por su parte, sirviéndose de descripciones y vocabulario médico, utiliza la enfermedad como un  recurso para plantear las consecuencias sobre la comunidad que proyecta la condición del personaje trágico. De esta manera, los textos se presentan como una visión diferente y \/>complementaria de la enfermedad y plantea la necesidad de revisar los tratados médicos (y científicos en general) en clave social.","palabras_clave":"ENFERMEDAD|COMUNIDAD|INDIVIDUO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":140879,"idioma_id":5,"titulo":"Contextos y sentidos de las prácticas escritas bilingües entre jóvenes wichis?,","resumen":"En este capítulo nos proponemos aportar algunos elementos para la comprensión de la emergencia de nuevas prácticas multilingües que involucran a las lenguas indígenas y al español en Argentina. Según sostendremos, el incremento fabuloso del acceso a la telefonía celular y a internet por parte de jóvenes de diferentes sectores sociales en los últimos años ha derivado en cambios importantes en las prácticas letradas, incluso entre quienes emplean cotidianamente lenguas de incipiente tradición escrita (Unamuno, 2013). Nuestro trabajo se basa en el estudio sociolingüístico del uso de la lengua wichi y del español en la interacción mediada por la tecnología (IMT), con especial referencia a las redes sociales digitales (Facebook). Para ello, nos detendremos en el análisis de un corpus de datos multimodales,  con el fin de dar cuenta de los usos bilingües (mezcla de códigos y alternancias de lenguas) en los contextos digitales a partir de su estudio conversacional y sociolingüístico (Gumperz, 1982; 1984; 1998; Mondada, 2007). Según argumentaremos aquí, el sentido de los usos bilingües escritos en los contextos digitales ha de ser comprendido en relación a las características particulares de la IMT en general, y a través del teléfono, en particular. Entre estas características, subrayamos el hecho que tales contextos albergan espacios de interacción definidos en la tensión entre lo privado y lo (semi)público. En estas condiciones, los usos de las lenguas minoritarias obtienen sentidos particulares, ligados a la forma de producir públicamente identidades etnolingüísticas individuales y colectivas. Nota: ISBN","palabras_clave":"BILINGÜISMO|ESCRITURA|NUEVAS TECNOLOGÍAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":140904,"idioma_id":5,"titulo":"Taller de Evaluación Sensorial de Productos Pesqueros","resumen":"Evaluación Sensorial de Especies Pesqueras y sus productosDeterminación de Nitrógeno Básico Volátil y pHActividad 1. Características de cada especieSe reconocerán las características morfológicas distintivas de cada especie presentada. Actividad 2. Se realizará la evaluación sensorial de la especie y producto que corresponda.Actividad 3. Se realizará la determinación de Nitrógeno Básico Volátil (NBV) y pHActividad 4. Se elaborará un informe con los datos obtenidos, se analizarán y discutirán los mismos y se arribará a Conclusiones.","palabras_clave":"EVALUACIÒN SENSORIAL|CALIDAD|FRESCURA|PRODUCTOS PESQUEROS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":141143,"idioma_id":5,"titulo":"Virus hepatitis A","resumen":"hepatitis A","palabras_clave":"HAV"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":141619,"idioma_id":5,"titulo":"Cianobacterias y cianotoxinas. Efectos en la salud humana. Casos informados y primeros acercamientos al estudio epidemiológico.","resumen":"Hace ya muchos años que se conocen, aunque aisladamente, casos de muertes o daños en la salud humana y animal relacionados con la exposición de éstos a aguas contaminadas con cianobacterias y sus toxinas. De estos casos y de estudios realizados sobre poblaciones expuestas se ha recabado una interesante cantidad de datos que tienen utilidad como evidencia en la necesaria epidemiología que debe realizarse en referencia a estos casos.La utilidad de estas evidencias radica en contar con una buena definición del caso clínico, una buena caracterización de las condiciones de exposición a cianobacterias y sus toxinas y la disposición de una base de datos que permita consultar y comparar dichos datos. La información con la que contamos surge principalmente de una serie de afecciones a la salud humana, debida a exposiciones agudas o crónicas a estas toxinas, que varían desde síndromes gastrointestinales, alteraciones respiratorias y cutáneas, promoción de tumores, hasta la muerte por fallo hepático con la importante característica de encontrarse ausente cualquier otro agente etiológico que usualmente puedeser el causante de estas afecciones. Debido a que los florecimientos de cianobacterias toxígenas constituyen uno de los graves problemas sanitarios relacionados con la fuerte eutrofización de los ambientes naturales, principalmente cuerpos de agua utilizados para obtener agua potable o como lugares de recreación, y a la ausencia de características especiales de estas intoxicaciones, que las distingan de otro tipo de afecciones que cursan con unasintomatología similar, es posible que las mismas puedan pasar desapercibidas o sean sub-diagnosticadas. Como consecuencia de ello surge la necesidad de poner en conocimiento del personal involucrado en el cuidado de la salud como médicos, bioquímicos, enfermeras, terapeutas, las características y existencia de casos documentados de daños o intoxicaciones debidas a diversas formas de contacto de la población con las cianobacterias y sus toxinas; con el fin de que incluyan esta posibilidad dentro de su práctica diagnóstica diaria. En este capítulo se discutirán los principales casos de afecciones a la salud humana vinculados conexposiciones agudas o crónicas a cianobacterias y sus toxinas, describiéndose las condiciones de exposición, sintomatología y evolución de los pacientes y alteraciones en los parámetros de laboratorio. Con el fin de una mejor comprensión dividiremos los casos en aquellos que generan efectos sobre la saluda corto plazo, los cuales derivan principalmente de intoxicaciones de tipo agudo, y los que producen efectos a largo plazo usualmente debidos a intoxicaciones crónicas con estas cianobacterias y sus toxinas.Finalmente comentaremos los primeros estudios de tipo epidemiológico realizados hasta el momento.","palabras_clave":"Cianobacteria|Cianotoxinas|salud humana|epidemiologia y casos"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":142333,"idioma_id":5,"titulo":"Matemática","resumen":"Teoría y práctica de Matemática a desarrollar en el curso de Ingreso","palabras_clave":"MANUAL|INGRESO|DEPARTAMENTO|ECONÓMICAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":142707,"idioma_id":5,"titulo":"Cianotoxinas. Farmacología y efectos de las principales toxinas presentes en Argentina. Microcystinas, Saxitoxinas, Anatoxinas, Cylindrospermopsinas, lipopolisacáridos.","resumen":"Las cianotoxinas son un grupo química y toxicológicamente diverso de toxinas naturales. A pesar de su origen acuático, la mayor parte de las cianotoxinas que se han identificado hasta la fecha parecen ser más peligrosas para los mamíferos terrestres que para la biota acuática. Las Cianobacterias sintetizan una gran variedad de metabolitos inusuales cuya función natural es variada y muchas veces no determinada. La investigación se ha centrado fundamentalmente en los compuestos que afectan a seres humanos y animales domésticos y en aquellos de interés farmacológico y biotecnológico. Otras gamas de productos no tóxicos también se han encontrando en cianobacteria y las características bioquímicas y farma cológicas de éstos son totalmente desconocidas. Los mecanismos de toxicidad cianobacterial descritos y entendidos actualmente son muy diversos y se extienden desde efectos hepatotóxicos, neurotóxico y dermatotóxicos a la inhibición general de la síntesis de proteínas. Para determinar los peligros específicos de toxinas cianobacteriales es necesario entender sus características químicas y físicas, su ocurrencia en las aguas utilizadas por la población, la regulación de su producción y su desarrollo en el ambiente.","palabras_clave":"Cianobacteria|Cianotoxinas|Farmacologia|Toxicología"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":161242,"idioma_id":5,"titulo":"Acumulación, poder y hegemonía. Algunos conceptos para la comprensión del territorio. (actualizado)","resumen":"El capitulo es el marco teórico del libro que sirve de articulación a todos los capítulos que lo integran.Las principales categorías que se plantean son territorio como ámbito de relaciones sociales; las categorías de la Escuela de la Regulación Francesa: régimen de acumulación y modo de regulación y las categorías gramscianas de bloque de poder y hegemonía.","palabras_clave":"Régimen de acumulación|Modo de regulación|Territorio|Bloque en el poder"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":161245,"idioma_id":5,"titulo":"La relación estado, economía y sociedad en la Provincia de San Juan en el periodo de transición (1976-1989)","resumen":"En este capítulo final, se procede a articular las categorías fundamentales abordadas en la introducción con los análisis de los capítulos anteriores. Esta tarea, pretende desentrañar la configuración de un territorio, la Provincia de San Juan, en el periodo 1976-1989 o periodo de transición. Por lo tanto, procesos sociopolíticos en dimensión histórica y entrelazados con las estructuras pretenden dar cuenta de las transformaciones en las relaciones sociales fundamentales y del papel del Estado como sostenedor de las mismas a la vez que árbitro de los conflictos sociales en esta etapa del capitalismo.","palabras_clave":"Estado|Economía|Bloque en el poder"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":161325,"idioma_id":4,"titulo":"Lateinamerika","resumen":"El estudio de la esclavitud grecorromana no tiene una larga tradición en América Latina, aunque varios estudios sobre la economía colonial han sugerido algunas notas comparativas con respecto a la esclavitud antigua. Dejando de lado estas observaciones incidentales, recientemente el tema ha sido estudiado en una serie de análisis de estudiosos mexicanos y argentinos. Es difícil establecer una relación directa a lo largo del tiempo entre las investigaciones sobre la esclavitud antigua y el contexto socio-político en América Latina, porque la escasa investigación realizada sobre este tema ha estado orientada por los debates historiográficos desarrollados en los centros académicos con una larga tradición en los estudios de la esclavitud. Sólo las investigaciones sobre la esclavitud moderna y la dependencia en América Latina han estado ligadas a las cambiantes circunstancias políticas e ideológicas del siglo XX (por ejemplo la alternancia entre democracias y dictaduras); pero esta situación no ha afectado a las líneas de investigación que los estudiosos han adoptado en relación con el mundo antiguo. A partir de esto, este artículo pondera los aportes latinoamericanos, exceptuando Brasil, a los estudios de la esclavitud antigua.","palabras_clave":"Antigüedad|Esclavitud|Dependencia|Historiografía"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":164615,"idioma_id":5,"titulo":"PLANIFICACIÓN AMBIENTAL SUSTENTABLE.  Área Metropolitana de San Juan","resumen":"El enfoque del trabajo que se expone a continuación se fundamenta en la necesidad de contribuir al conocimiento ambiental del Área Metropolitana de San Juan, para proponer herramientas de planificación urbana sustentable, orientadas al campo bioclimático de ambientes áridos. Por tanto, se presentan resultados de investigaciones que estudian integradamente aspectos urbanos de la ciudad en relación con las características climáticas del espacio en el cual se manifiestan. Se parte del análisis de los principales indicadores urbanísticos para definir las Bandas Urbanas Características. La masa térmica urbana conforma la base de datos que se aplica en estudios de interrelación con el clima urbano resultante de dicha urbanización. Se analiza la isla de calor, uno de los principales aspectos de ese clima urbano. Se estudia la forestación pública en su rol bioclimático, como aporte a la disminución de dicha isla de calor. Los árboles se examinan individualmente por especies arbóreas y luego conformando espacios verdes urbanos (EVU). Se cuantifica la cobertura higrotérmica arbórea del AM San Juan y se obtienen isotermas estacionales de la ciudad, donde se verifica la influencia de los EVU.","palabras_clave":"PLANIFICACIÓN URBANA|BANDAS URBANAS CARACTERÍSTICAS|CLIMA URBANO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":165380,"idioma_id":5,"titulo":"Entrada: 'Testigo'","resumen":"TESTIGO: etimológicamente, del griego: mártûs; y del latín: testis. Testigo es quien ha presenciado un acontecimiento y testimonia frente a alguien lo que dice haber visto u oído. El testigo es quien da cuenta de lo que ha presenciado describiendo la escena, de forma oral, escrita u ostensiblemente; y estableciendo relaciones entre lo visto u oído. El testigo realiza su declaración desde una posición de tercero respecto a los protagonistas de una acción. Sin embargo, Benveniste recuerda que también superstes hace referencia al testigo. Así, mientras testis designa a ?quien asiste en tercer lugar [terstis] en un asunto en el cual dos personajes están interesados? (1969: 277); superstes remite a quien ?sobrevive más allá de?, al testigo que es al mismo tiempo sobreviviente, que estuvo allí y ahora está presente.   También es testigo quien da fe, o confiesa su fe, en favor de algo o alguien; de ahí una de las derivaciones del término griego: el mártir. En este sentido, el mártir es un testigo que sufre, o incluso perece, por lo que cree y pretende atestiguar. Como Sócrates o Jesús, afirma Ric?ur, ?es el hombre que se identifica con la causa justa, odiada por la muchedumbre y los grandes, y por esta causa justa arriesga su vida? (1983: 22). Aunque son pocas las ocasiones en que se llega a esas instancias, esa clase de atestiguación va más allá de una articulación de palabras y una relación establecida entre acontecimientos, se trata de una ?atestación por la acción y por la muerte? (Ibídem: 23).","palabras_clave":"TESTIGO|DEFINICIÓN|ANTECEDENTES|ALCANCES CONTEMPORÁNEOS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":165765,"idioma_id":5,"titulo":"Sarmiento y Gallegos","resumen":"El ensayo traza resonancias no sólo temáticas sino operaciones de escritura entre El Facundo de D.F. Sarmiento y Doña Bárbara de Rómulo Gallegos.","palabras_clave":"SARMIENTO|GALLEGOS|FACUNDO|DOÑA BARBARA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":165852,"idioma_id":5,"titulo":"Interacciones. Enlazados evolutivamente","resumen":"Las especies de todos los grupos de organismos interactúan y están estrechamente relacionadas con otras por medio de una amplia variedad de mecanismos. Éstos se han desarrollado a lo largo del tiempo por coevolución: un proceso permanente de selección recíproca entre organismos interrelacionados. Los sistemas de relación son promotores de  la generación de biodiversidad; la complejidad característica de las interacciones entre especies a lo largo de tiempos geológicos no solamente ha resultado en una enorme abundancia y diversidad de organismos en tiempo y espacio, sino que también ha generado muchas de las adaptaciones evolutivas que encontramos hoy en el mundo biológico. Las interacciones pueden variar desde simples relaciones entre dos especies, hasta complejas interrelaciones que involucran numerosas especies e intrincados mecanismos. Las consecuencias en la evolución de las especies son diversas, dependiendo de los efectos sobre cada participante.  Los tipos de interacción varían desde las de tipo mutualista en la cual todas las especies involucradas se benefician (este es el caso de la polinización biológica o de la dispersión de semillas, por ejemplo), hasta relaciones de tipo antagonista, en la cual la relación es  negativa para al menos una de ellas (por ejemplo, las relaciones predador-presa o las de parasitismo, beneficiosas para una de las especies y negativas para la otra). En la competencia, en cambio, ambas especies aprovechan los mismos recursos, llegando a excluirse cuando estos son insuficientes para la coexistencia de poblaciones numerosas  de ambas especies. Existen también relaciones de tipo neutral, que no afectan directamente la relación entre las especies involucradas. El mimetismo es otro tipo de interacción entre especies. En ella, el ?modelo? y el ?imitador? no interactúan directamente, sino que ambos se relacionan con un tercero, que es el predador. Hay numerosos ejemplos en los cuales una especie de insecto es muy similar en forma y\/o textura a  algunas plantas, sobre las que se protege o caza sin ser detectado. Por otro lado, muchos animales poseen los mismos patrones de color o el comportamiento de especies venenosas o tóxicas, lo que se convierte en un medio de defensa, ?advirtiendo? al potencial depredador sobre un peligro que en realidad no existe. Esta forma de ?camuflaje? se conoce como mimetismo aposemático.  La existencia de una especie en un ambiente necesariamente influye sobre la supervivencia, el comportamiento y la reproducción de otras especies y esto es un proceso constante. De esta forma, por ejemplo, los herbívoros desarrollaron modificaciones en su conformación, en su fisiología y en su comportamiento, que los hicieron particularmente aptos para alimentarse de diferentes partes vegetales, y por su lado, las plantas cambiaron  a formas que dificultan ser comidas. Asimismo, los predadores desarrollaron complejos mecanismos con los que superan las defensas de sus presas, al tiempo que estas cambian espontáneamente de modo que evitan hasta cierto punto ser capturadas.  La evolución de espinas o de defensas químicas en las plantas también pudo haber sido modulada por la presión natural de selección resultante de la relación con los herbívoros a lo largo del tiempo. A su vez, la fisiología de los modernos herbívoros pudo haber sido modificada al mismo tiempo, con mecanismos de detoxificación o mediante superficies  coriáceas (duras) en sus lenguas o labios, con lo que se sobreponen a los mecanismos de defensa desarrollados por las plantas. En relación a la polinización, las plantas desarrollaron estructuras vistosas (flores) que atraen a los polinizadores, así como sustancias dulces (néctar) que el polinizador obtiene a modo de ?recompensa? por el ?servicio? que estos animales les brindan.  En las interacciones, y dependiendo de la escala en la que se analicen, no todo es como parece. Por ejemplo, en general se cree que las relaciones de tipo antagonista son perjudiciales para uno de los integrantes de la interacción. Esto es así cuando se analiza a nivel de individuos; pero si el análisis se lleva a nivel de la población, el resultado suele ser diferente. Suele suceder que el impacto de los predadores a nivel poblacional beneficia a las especies presa, puesto que contribuyen a eliminar individuos enfermos o débiles, favoreciendo la supervivencia de los más saludables. También ocurre que la herbivoría  promueve la regeneración y dinámica de las comunidades vegetales. En biomas megadiversos, se estima que cada especie de plantas puede estar asociada directa o indirectamente con unas 200 o 300 especies de animales.  Como se verá, la trama de interacciones es enorme y compleja, y probablemente hayamos explorado solo la ?punta del iceberg? quedando aún un mundo por descubrir y comprender. Las historias (interacciones) que vamos a presentar en este capítulo ponen de manifiesto sobre todo lo mencionado antes respecto de las interrelaciones biológicas, su dinámica y el carácter inacabado: ninguna especie evoluciona sola; siempre hay otros organismos involucrados en un proceso coevolutivo por medio del que los cambios de una especie modifican las condiciones de vida de otra u otras, día a día, todo el tiempo.","palabras_clave":"INTERACCIONES|BOSQUE CHAQUEÑO|ANIMALES |PLANTAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":166148,"idioma_id":4,"titulo":"Early to Middle Holocene Climatic Change and the Use of Animal Resources by Highland Hunter-Gatherers of the South-Central Andes","resumen":"A paradox regarding the relationship between environmental change and the use of animal resources by hunter-gatherers has become common place in archaeological and anthropological literature. On the one hand, environmental carrying capacity and its evolution through time has emerged as a key feature in most theoretical models of behavioral ecology and other ecological perspectives in hunter-gatherers studies. On the other hand, the relationship between environmental changes and the actual impact on animals and other resources important for human subsistence remain almost unexplored in empirical terms, with a few exceptions (Grayson 2000; Broughton et al. 2008; Wolverton 2008). With this in mind, the goal of this paper is to study the relationship between the use of animal resources by hunter-gatherers and the environmental modification that occurred with the onset of Middle Holocene aridity in the southern Altiplano of the Andes.","palabras_clave":"Isotopes|Holocene|Hunter-Gatherers|Animal resources"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":166250,"idioma_id":5,"titulo":"Testimonio","resumen":"En el trabajo se distinguen los distintos alcances que el concepto de testimonio alcanza en la historia.    Nota: se colocó un ISBN cualquiera ya que todavía la publicación no lo tiene y el sistema no permite cargar la información sin ese dato.","palabras_clave":"TESTIMONIO|HISTORIA|TRAUMA|REFERENCIAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":168045,"idioma_id":5,"titulo":"¿Es el 'argumento del conocimiento' un argumento acerca del conocimiento?","resumen":"Todo el mundo coincide con la idea de Jackson (1982) de que lo que adquiere María al salir de su prisión es un nuevo conocimiento, las diferentes interpretaciones y respuestas al argumento tratan de especificar el tipo de conocimiento involucrado en este caso. Sin embargo, surgen muchas dificultades al tratar de clarificar en qué consiste este conocimiento. El propósito de este trabajo es defender dos ideas. Primero, trataré de mostrar que todas las respuestas fisicalistas a este problema tienen serios problemas.  Segundo, quiero proponer una lectura diferente de la conclusión del argumento del conocimiento, negando que sea correcto decir que en el momento mismo de su liberación María adquiere algo que merezca ser llamado conocimiento. Más específicamente, distinguiré tres tipos de relaciones que un sujeto puede tener con sus estados mentales: conocimiento, percatación (awareness) y sensación (feeling, experiencing). Mi propuesta es que el estado mental de María al ser liberada es el de una nueva experiencia que por sí misma no puede ser considerada un tipo de conocimiento.","palabras_clave":"qualia|conocimiento proposicional|saber cómo|conocimiento directo"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":171526,"idioma_id":5,"titulo":"Canon","resumen":"Esta entrada de manual se propone revisar y presentar las principales discusiones en torno a la noción de canon vigentes en el campo de los estudios literarios.","palabras_clave":"LITERATURA|TEORÍA LITERARIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":171527,"idioma_id":5,"titulo":"Literatura","resumen":"Esta entrada  propone ofrecer a estudiantes que ingresan en la carrera de Letras un recorrido que les permita comprender la complejidad de la noción de literatura, revisando los principales aportes y perspectivas desarrollados por las teorías literarias del siglo XX.","palabras_clave":"ESTUDIOS LITERARIOS|TEORÍA LITERARIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":174775,"idioma_id":4,"titulo":"SHORT-DISTANCE VOCALIZATIONS OF THE BLACK-AND-GOLD HOWLER MONKEY (ALOUATTA CARAYA) IN THE ATLANTIC FOREST OF ARGENTINA","resumen":"The vocal behavior of howler monkeys (Alouatta spp.) includes long and short-distance vocalizations, the latter of which have seldom been studied. Naturally emitted short distance vocalizations (used in intra-group communication) of two groups (26 individuals) of black-and-gold howler monkeys (Alouatta caraya) in the Atlantic Forest of Argentina, were recorded during a period of six months (June 2007-November 2007). For each sound-recording, sex and age of the sender and behavioral context (feeding, playing, aggression between group members, isolation, tense moments and infant distress situations) were noted. Four spectrogram measurements (minimum, maximum and peak frequency and duration) were taken in 331 calls using the software Raven 1.4 (Cornell University). We recognized (by sound and form) eight different types of short-distance calls: Hu-hu-hu, Heh, Bark, Moo, Ar, Yell, Screech and Oodle. Although we did not test functionality, the consistency of some of the contexts in which the signals were recorded show that some of these vocalizations can function to reestablish contact between lost individuals (Moo call), as a warning of a close danger (Bark), or during aggressive interactions between group members (Screech). This descriptive study sets the stage for future ones designed to test hypotheses about the proximate mechanisms and function of each call to further our knowledge of intra-group communication in howler monkeys.","palabras_clave":"BLACK-AND-GOLD HOWLER MONKEY|INTRA-GROUP COMMUNICATION|VOCAL REPERTOIRE"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":174780,"idioma_id":4,"titulo":"THE BROWN HOWLER MONKEY (ALOUATTA GUARIBA CLAMITANS) IN ARGENTINA: CURRENT STATUS, THREATS AND CONSERVATION CHALLENGES","resumen":"The brown howler monkey (Alouatta guariba clamitans) is an endemic species of the Atlantic Forest of Brazil and Argentina. It persists at extremely low densities over an area of &lt;10.000 km2 in the central-eastern portion of Misiones Province, and its presence has been confirmed in five small strictly protected areas. The species is classified as Critically Endangered for Argentina. The objectives of this contribution are to review our knowledge on brown howler?s status, analyze the main threats and challenges that affect the species in Misiones and recommend some necessary steps for the development of a conservation strategy for this population.   Most of our knowledge on the brown howler in Argentina comes from a study conducted at El Piñalito Provincial Park between 2005 and 2007. Following the 2008-2009 yellow fever outbreak, brown howlers have been decimated throughout the region.  Brown howlers have being affected by progressive and severe habitat loss in Misiones. In addition, as all members of the genus, this species is particularly susceptible to epidemic diseases such as yellow fever. Thus, recurrent yellow fever epidemics coupled with the high susceptibility of howlers to this disease may be the most important threat to the persistence of this small population in Argentina. Finally, these two threats, habitat loss and yellow fever, are further compounded by a lack of awareness among governmental, non-governmental institutions and general public. A recent workshop on brown howlers in Argentina that used Population Viability Analysis as a tool indicates yellow fever as the main threat to this brown howler population persistence. The threat analysis, focused on the dynamics of yellow fever outbreaks and their impact on howler populations, led to the identification of gaps in knowledge that helped prioritize objectives and actions for the development of a Species Conservation Strategy in Argentina.","palabras_clave":"BROWN HOWLER MONKEY|THREAT ANALYSIS|POPULATION VIABILITY ANALYSIS|YELLOW FEVER"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":176134,"idioma_id":5,"titulo":"La intoxicación etílica en tempranas fases del desarrollo: Impactos morfológicos y funcionales","resumen":"Generalmente, la visión de los efectos nocivos del alcohol sobre el individuo y la sociedad se deriva de patrones de uso y abuso del psicotrópico por parte del adolescente y el adulto. Dicha visión se centra en el desarrollo de la adicción hacia el alcohol, enfermedades de orden neurológicas y hepáticas asociadas a la ingesta abusiva, coparticipación del alcohol en el aumento del riesgo en contraer patologías venéreas, mortalidad o incapacitación generada por accidentes de tránsito y laborales bajo estado de ebriedad, violencia familiar y social, etc. Sin embargo, enfocar la problemática etílica sólo a partir del consumo juvenil o adulto implica un sesgo ontogénico y posiblemente resta efectividad al análisis de causas o factores moduladores que subyacen al desarrollo de patrones de uso y abuso del psicotrópico.  El objetivo del presente capítulo es retrotraer nuestra visión a etapas tempranas del desarrollo presentando evidencias preclínicas, clínicas y epidemiológicas sobre los riesgos de la exposición fetal, infantil y adolescente sobre el bienestar del individuo y principalmente ilustrar como estas experiencias pueden repercutir sobre la subsiguiente afinidad etílica y la sensibilidad hacia los efectos motivacionales de la droga. Las temáticas que recibirán especial interés implican tempranas capacidades para procesar y retener información sensorial (gustativa y olfatoria) inherente al alcohol, la sensibilidad a los efectos reforzantes de la droga, la generación de aprendizajes asociativos a partir de la contigüidad temporal entre la percepción sensorial etílica y sus efectos interoceptivos, la interacción entre experiencias del feto y el lactante con el alcohol sobre la posterior ingesta y búsqueda de la droga, el rol del principal metabolito del alcohol (acetaldehído) en la generación de efectos reforzantes a nivel del sistema nervioso central y consecuencias de la sensibilidad periadolescente frente al desafío etílico.  A fin que el lector pueda lograr una mejor comprensión sobre los temas aquí abordados, resulta pertinente brindar una visión resumida sobre dos aspectos relevantes en cuanto al desarrollo temprano. El primero de ellos implica la posibilidad de patologías durante el desarrollo embrionario y fetal debido al consumo materno de alcohol. Nos referiremos al problema del alcohol en calidad de teratógeno (agente con la capacidad de inducir o aumentar la incidencia de malformaciones congénitas cuando se administra o actúa durante la organogénesis). Conjuntamente analizaremos otras formas de exposición postnatal temprana al psicotrópico que existen en diversas culturas y que han recibido relativamente poca atención en referencia a sus efectos a corto y largo plazo. En segundo lugar, abordaremos brevemente evidencias sobre capacidades tempranas de percepción, aprendizaje y memoria; capacidades que pueden observarse durante la vida prenatal tardía y durante la lactancia. El objetivo de estos abordajes es permitir una visión integrada acerca de la factibilidad de experiencias tempranas con la droga y como dichas experiencias pueden modificar la sensibilidad hacia el alcohol  y la búsqueda y el consumo del psicotrópico.   El descubrimiento que el alcohol posee la capacidad de actuar como un agente teratogénico amplió considerablemente el espectro de alteraciones que es posible esperar a partir del uso y abuso de este psicofármaco (Jones & Smith, 1973; Lemoine, Harousseau, Borteyru, & al., 1968). Actualmente, dos entidades nosológicas aluden a los efectos adversos del uso del alcohol durante la gestación. El Síndrome Fetal de Alcohol (en la literatura anglosajona: Fetal Alcohol Syndrome o FAS) implica un espectro de malformaciones craneofaciales (entre otras: perímetro craneal disminuido, fisuras palpebrales pequeñas, ausencia de pliegue nasolabial o philtrum, labio superior largo y delgado, hipoplasia del maxilar inferior), retraso en la tasa de crecimiento fetal e infantil y un amplio espectro de trastornos neurológicos que se expresan a través de disfunciones lingüísticas, alteraciones sensoriales, perceptuales y en la coordinación motora y déficits en la capacidad de aprendizaje y memoria. El llamado Espectro de Desórdenes Fetales producidos por el alcohol (Fetal Alcohol Spectrum Disorders o  FASD) es diagnosticado en niños con disfunciones neurológicas asociadas con la historia de ingesta materna durante el embarazo pero que no presentan las típicas alteraciones morfológicas del FAS (Riley & McGee, 2005). Tomadas en conjunto, estas dos entidades patológicas representan en el mundo occidental la primera causa congénita asociada a alteraciones neurocomportamentales, entre las que se incluye el retraso mental (en calidad de revisiones recientes véase: (de Sanctis, Memo, Pichini, Tarani, & Vagnarelli; Fernández-Mayorales & Fernández-Jaén, 2011; Riley, Infante, & Warren, 2011). La severidad de los desórdenes morfológicos o funcionales generados por el insulto etílico embrionario o fetal depende de una multiplicidad de factores. Entre ellos,  la cantidad y frecuencia del consumo materno. El llamado ?atracón etílico? o ?binge drinking? (altas dosis en poca cantidad de tiempo) implica un factor de alto riesgo teratológico. Nótese que dicho tipo de consumo, en la actualidad, es característico en poblaciones jóvenes en edad reproductiva. Influyen también en la naturaleza y la magnitud de las alteraciones fetales, la hiponutrición y la capacidad metabólica materna (Shankar, Ronis, & Badger, 2007) y el período de gestación en el que se produce el desafío etílico (Kumada, Jiang, Cameron, & Komuro, 2007; Maier, Miller, Blackwell, & West, 1999; Sulik & Johnston, 1983; Zhou, Sari, Powrozek, Goodlett, & Li, 2003).  En términos del desarrollo del sistema nervioso central y considerando la multiplicidad de procesos que determinan su configuración morfológica y funcional (inducción de la placa neural, proliferación neuronal y glial, migración, agrupamiento, sinaptogénesis, muerte neuronal programada y reorganización de los circuitos neurales), resulta imposible considerar a cualquier etapa de la ontogenia cerebral como refractaria a efectos adversos del alcohol.     La posibilidad de exposición temprana al alcohol no se circunscribe al periodo del embarazo. La investigación epidemiológica y clínica indica que también existen otras modalidades de exposición a la droga durante el transcurso de la temprana ontogenia (en carácter de revisiones, véase (Molina, Spear, Spear, Mennella, & Lewis, 2007; Spear & Molina, 2005). En distintas culturas, incluyendo a nuestro país (Argentina), se continúa utilizando paños embebidos en alcohol con la finalidad de evitar infecciones neonatales derivadas del remanente del cordón umbilical o buscar disminuir espasmos estomacales en el lactante. Estas prácticas implican la absorción percutánea del alcohol e inhalación del vapor etílico lo que genera considerables niveles de la droga en sangre (Choonara, 1994). El consumo materno de alcohol durante la lactancia, basado en la creencia científicamente no sustentada sobre su poder galactogénico, representa otra forma de exposición temprana a la droga. Si la cantidad ingerida no inhibe la producción y eyección de leche, fenómenos relacionados con alteraciones en los niveles de oxicitocina y prolactina, el lactante estará expuesto a leche contaminada con alcohol. Esta exposición es suficiente para generar memorias relacionadas con el alcohol (Giglia & Binns, 2006;  Mennella & Beauchamp, 2002; Mennella, Pepino, & Teff, 2005) o alterar la interrelación socioafectiva y nutricional entre la madre y el bebé (Pepino, Abate, Spear, & Molina, 2002a; Pueta, Abate, Haymal, Spear, & Molina, 2008).  Finalmente, recientes estudios epidemiológicos reflejan la alta prevalencia de consumo y abuso etílico tanto en niños como en adolescentes en prácticamente todos los países examinados (Ahlstrom & Osterberg, 2005; Johnston, O?Malley, & Bachman, 2005).  Los efectos nocivos a corto y largo plazo que ejerce el alcohol, incluyendo entre ellos a los patrones de abuso y adicción, dependen significativamente de la edad de inicio del consumo o la exposición a sus efectos tóxicos (Ahlstrom & Osterberg, 2005). Cuatro trabajos epidemiológicos indican que la exposición prenatal al alcohol, derivada incluso de patrones moderados de consumo materno, es un factor que predice el subsiguiente abuso etílico (Alati, et al., 2006; Baer, Barr, Bookstein, Sampson, & Streissguth, 1998; Baer, Sampson, Barr, Connor, & Streissguth, 2003; Yates, Cadoret, Troughton, Stewart, & Giunta, 1998). Esta asociación es aun significativa al controlar variables intervinientes que por sí mismas pueden determinar el hábito de ingesta (por ejemplo: predisposición genética, co-utilización de otros psicotrópicos durante el embarazo y características del entorno familiar a nivel postnatal). La mayoría de estos estudios reconoce como antecedente a la información preclínica, generada a través de modelos animales, que sustenta  la asociación bajo consideración y provee mecanismos por los cuales se establece la misma (por ejemplo: Chotro & Arias, 2006; Molina, Chotro, & Domínguez, 1995; Molina, et al., 2007; Spear & Molina, 2005).  Una significativa fracción de los estudios conducidos por nuestro laboratorio está abocada a comprender como la experiencia temprana con el alcohol (entendiendo por temprana a etapas tardías de la gestación, las primeras horas de vida postnatal, la fase de lactancia y el comienzo de la vida juvenil) determina o modula la subsiguiente reactividad hacia atributos sensoriales y tóxicos de la droga, cómo afecta la búsqueda de estímulos originalmente asociados a los efectos interoceptivos del alcohol y finalmente cómo incide sobre la estructuración de patrones de consumo etílico. Por lo general los estudios implican la utilización de dosis etílicas bajas o moderadas que no generan alteraciones teratológicas a nivel fetal ni alteraciones fisiológicas permanentes durante la temprana vida postnatal. Se utilizan modelos animales que permiten  analizar como el contacto temprano con el alcohol puede dar origen a aprendizajes y memorias específicas, su incidencia sobre procesos de sensibilización o tolerancia hacia el alcohol y como estos factores se entrelazan para determinar conductas de búsqueda o ingesta de la droga. Basados en estas aproximaciones experimentales y cuando existieron posibilidades metodológicas, técnicas y fundamentalmente de cumplimiento con normativas éticas, también se realizaron investigaciones en la esfera humana. Por ejemplo, a partir de estudios que demuestran la capacidad de procesamiento quimiosensorial por parte del feto de especies altriciales, hemos investigado patrones de reconocimiento del olor etílico en neonatos humanos cuyas madres exhibieron patrones de ingesta etílica moderada durante el embarazo (Faas et al., 2000). En coincidencia con estudios animales que indicaban que el feto a término procesa estímulos olfativos presentes en el líquido amniótico (Molina, et al., 1995; Schaal, Hummel, & Soussignan, 2004) pudo demostrarse que la exposición prenatal al alcohol promueve el reconocimiento postnatal de los atributos sensoriales de la droga. Este efecto es altamente específico ya que no se observa generalización hacia otros estímulos y es detectable en niños que no exhiben signos o síntomas característicos de la acción teratogénica del alcohol (Faas, Sponton, Moya, & Molina, 2000).   Brindado este ejemplo, y como fuese originalmente señalado, resulta conveniente que el lector también pueda comprender capacidades de percepción y de aprendizaje presentes en la ontogenia temprana. Abordaremos en forma resumida estas capacidades para facilitar la subsiguiente comprensión acerca del rol de la experiencia temprana con el alcohol sobre subsiguientes pautas de reconocimiento y aceptación de la droga. Durante la vida fetal es posible concebir un rico contexto de estímulos a los que está expuesto el organismo en desarrollo. La capacidad para reaccionar a estímulos cutáneos, vestibulares y térmicos emerge rápidamente en el feto. De hecho, la re-exposiciòn a estímulos experimentados durante la gestación tardía, generan en el neonato claras respuestas de orientación en el plano comportamental y neurovegetativo (Alberts, 1984; Ronca, Kamm, Thelen, & Alberts, 1994).   En referencia a los estímulos quimiosensoriales existen evidencias de la funcionalidad del sistema olfatorio durante la vida fetal de ciertos mamíferos; por ejemplo en el ratón (Coppola, 2001) y en el humano (Schaal, et al., 2004). Un cuerpo considerable de investigaciones neurobiológicas ha demostrado que fetos a término como neonatos de distintas especies (conejos, ovejas, ratas y humanos; Robinson & Smotherman, 1995 Robinson, Hoeltzel, & Smotherman, 1995; Schaal, et al., 2004) detectan y discriminan estímulos quimiosensoriales presentes en el líquido amniótico o en el ambiente postnatal; respectivamente. Tanto en ratas como en humanos, es claro que existe memoria relativa a atributos sensoriales del líquido amniótico que repercuten  sobre la orientación y preferencia del neonato hacia el olor de este fluido biológico; orientación que también modula la búsqueda y prensión del pezón materno aromatizado con olores percibidos in útero (Schaal, Marlier, & Soussignan, 2000; Smotherman, 1984). Como lo señala Nicolaidis (2008), la experiencia prenatal con estímulos gustativos y olfatorios específicos puede dar lugar a aprendizajes similares a la impronta que determinan subsiguientes pautas de preferencias hacia determinadas dietas e incluso hacia drogas tales como el alcohol.  Se observa también a nivel fetal y neonatal la capacidad de habituarse a estímulos que son presentados en forma monótona y que no implican relevancia biológica. La habituación, una forma simple de aprendizaje no asociativo, ha sido observada a nivel conductual y neurovegetativo en el feto de rata a término ante la estimulación repetida con un olor artificial (Smotherman & Robinson, 1992). Similar proceso de aprendizaje ha sido constatado en el feto ovino y humano ante estímulos de orden vibroacústicos (Hepper & Dornan, 2012; Leader, Baillie, Martin, Molteno, & Wynchank, 1984; Leader, Stevens, & Lumbers, 1988). Avances técnicos y metodológicos han permitido también analizar si el feto a término y el neonato de rata poseen la capacidad de adquirir, retener y expresar aprendizajes de orden asociativos. La respuesta ha sido afirmativa y como se verá en el desarrollo del capítulo, este tipo de aprendizaje ha sido investigado sistemáticamente con el alcohol a fin de evaluar la capacidad reforzante de la droga durante distintas etapas de la ontogenia temprana. Cabe señalar que los aprendizajes asociativos a nivel fetal y neonatal han sido originalmente investigados valiéndose de distintos procedimientos experimentales. Por ejemplo, se han obtenido evidencias de condicionamiento clásico o pavloviano, aversivo o apetititvo, al asociar estímulos olfativos y gustativos con agentes eméticos, estimulación táctil activadora del movimiento o leche infundida a nivel intrabucal (Domínguez, López, & Molina, 1999; Gruest, Richer, & Bernard, 2004; Petrov, Varlinskaya, & Smotherman, 2000; Smotherman, Richards, & Robinson, 1984). Una reciente serie de estudios experimentales ha puesto también de manifiesto que los roedores recién nacidos, rápidamente asocian distintos comportamientos con reforzadores naturales, tal el caso de la leche. En función de dicha asociación, el organismo logra auto-administrarse el agente nutricional e incluso presenta conductas de búsqueda del reforzador (Arias, Spear, Molina, & Molina, 2007; Bordner, Molina, & Spear, 2008; March, Abate, Spear, & Molina, 2009).  En resumen, esta introducción a la temática específica, ha intentado dar un contexto de conocimiento relativo a posibilidades de exposición temprana al alcohol, sus efectos adversos sobre el desarrollo del organismo y también señalar que existen capacidades de aprendizaje temprano; las cuales, a través de distintos procesos, pueden afectar el comportamiento subsiguiente. Los ítems que se abordarán a continuación resaltarán experiencias tempranas con el alcohol, los aprendizajes que se derivan de las mismas y su impacto sobre la subsiguiente apetencia y afinidad etílica.","palabras_clave":"ALCOHOL|DESARROLLO TEMPRANO|APRENDIZAJE Y MEMORIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":176142,"idioma_id":5,"titulo":"Conflicto","resumen":"Análisis del concepto de 'conflicto' y de sus antecedentes históricos en el pensamiento político y social.","palabras_clave":"Conflicto|Acción|Política"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":177113,"idioma_id":4,"titulo":"Behaviour and Ecology of Pomacea canaliculata in Southern Pampas","resumen":"Pomacea canaliculata is in many aspects the best known species among apple snails (family Ampullariidae) although the available information is both fragmentary and geographically biased. Most studies in the exotic range focused in applied aspects in man-managed or artificial wetlands scattered over different countries in South Eastern Asia. In the natural range, on the contrary, the emphasis has been on basic studies of its reproductive biology, ecology and behaviour in populations from small streams located at the southernmost extreme of its distribution (Southern Pampas, Argentina). The extreme geographic position and the lotic nature of these populations may have biased some conclusions about the etoecological traits of P. canaliculata; contemporary evolution and genetic exchange may have also diversified these traits in the invaded range. Even though the ecological information from native populations may not be directly applicable elsewhere, it nevertheless remains as a necessary reference to understand the full potential of adaptation and spread of P. canaliculata to new environments around the world. Surprisingly enough, comparative studies of native and exotic populations of Pomacea spp. are almost lacking.","palabras_clave":"Pomacea canaliculata|Invasiveness|Morphology"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":177162,"idioma_id":4,"titulo":"PRIMATES FROM THE INSIDE: GENOMES AND CHROMOSOMES","resumen":"Earlier studies on primates in Ar¬gentina were carried out in the 1980?s, and dealt with descriptions at the species level of specimens kept in zoos and animal houses. Some of the species were used as models in biomedical research because of their close relationship with humans, giving rise to basic and applied studies. Over the next 20 years, there was a noticeable leap in both methodological and theoretical development when the population level was included in the debate about the concept of species, and evolutionary relationships among them. We deepened our knowledge of chromosomal rearrangements valuable from an evolutionary point of view in Argentine species by describing heterochromatin polymorphisms ?which are distinctive characteristics for some genera?. At the same time, particular structural rearrangements were described, such as multiple sex systems, which were characterized by meiotic studies and genomic conservation analysis using Fluorescence in situ Hybridization (FISH). At the molecular genetic level, studies of variability in mitochondrial and nuclear DNA polymorphisms contributed to characterize the intra- and interspecific variability of primate species from Argentina. These qualitative studies provided an interpretation of the evolutionary process at the level of family, proposing a chromosomal phylogeny related to other taxonomic variables, among other issues. A second methodological and argumentative leap was achieved with the introduction of Comparative Genomic Hybridization (CGH), which allows analyzing how much of the genome is shared among congeneric species and on what chromosomes differences are located. Currently, our approach for studying primates allows the analysis of the structure and organization of the cell nucleus in the context of genome dynamics. Within this framework, we discuss how the evolutionary process might occur and how primate genomes might be modulated.","palabras_clave":"CYTOGENETICS|GENOMES|PLATYRRHINI|EVOLUTION"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":177891,"idioma_id":5,"titulo":"Alfabetización y evangelización: una mirada comparada acerca de propuestas educativas hacia los qom en el marco de congregaciones religiosas","resumen":"La participación de las congregaciones religiosas en la educación indígena en la Argentina ha adquirido distintas formas a lo largo de la historia, incidiendo tanto las doctrinas y estrategias de intervención de cada uno de los credos, como las políticas estatales, la región y el colectivo étnico implicados. Especialmente desde el siglo XIX, los qom fueron objeto de acciones específicas por parte de misioneros que, en localizaciones urbanas y rurales del Chaco, articularon de modo diverso la evangelización y la alfabetización en español. Teniendo en cuenta estos antecedentes, este trabajo se propone comparar dos intervenciones educativas producidas en los años 60? y 90? en relación con el colectivo qom por parte de congregaciones religiosas: la acción misional protestante en la ciudad de Castelli entre 1964 y 1972, y la escolarización católica en un Barrio Toba del Gran Buenos Aires desde 1995 hasta el 2006. La elección de estas dos intervenciones religiosas sobre un mismo colectivo étnico nos permitirá desplegar las características que asumió cada propuesta educativa y a la vez problematizar algunos rasgos en su historicidad, en particular el papel otorgado a la lengua indígena y la inculcación de la doctrina religiosa en las propuestas de educación intercultural.En la comparación es necesario advertir dos dimensiones claves para profundizar el sentido histórico de las diferencias entre las intervenciones educativo-religiosas sobre el colectivo Qom: una de ellas es que la experiencia de Castelli se dio en un marco misional de educación no formal, destinada a niños, jóvenes y adultos, mientras que la del GBA se desarrolló dentro de una escuela primaria. Esta diferencia se vincula con el propio desarrollo de la educación destinada a poblaciones indígenas en la Argentina, donde los primeras intervenciones se desarrollaron en contextos religiosos, siendo el Estado (y a través de él, las escuelas) actor central en la actualidad. La segunda dimensión a considerar es el de los diferentes contextos socio-históricos y religiosos en que se producen ambas propuestas, donde como veremos, las relaciones contemporáneas del colectivo con la iglesia católica en Buenos Aires pueden entenderse en relación con las vinculaciones establecidas décadas atrás con las congregaciones protestantes en Chaco. En este sentido en el capítulo presentaremos, en primer lugar, la expansión del evangelismo en su interpenetración con las prácticas de lectura y escritura de la biblia en idioma qom en los ?60, y en segundo lugar, su contracara de desmarcación indígena en la intervención católica para los alumnos tobas en los ?90. Estos hallazgos se apoyan en dos trabajos de campo. Uno se inició en 2011 en las provincias del Chaco y Buenos Aires (localidades de Resistencia, Juan J. Castelli, El Sauzalito, y Villa Lugano, respectivamente), donde se relevaron documentos y se efectuaron entrevistas a los protagonistas de las intervenciones educativas religiosas (Almirón 2011, 2013). Esta investigación se vincula con un proyecto que estudia la historia de la enseñanza de la lectura y escritura en varias localizaciones del país desde mediados del Siglo XX.  El segundo trabajo de campo se efectuó en dos etapas, la primera de ellas entre 2005 y 2006 y la segunda entre 2010 y 2012, en un barrio de la zona norte del conurbano de la provincia de Buenos Aires, donde se realizaron observaciones de clase y entrevistas abiertas al personal docente y a los padres de los alumnos indígenas (Borton, 2011). Esta segunda investigación se vincula con varios proyectos que abordan las experiencias formativas e identificaciones contemporáneas en distintos colectivos étnicos y de migrantes del país .En virtud de los acuerdos de confidencialidad que se efectuaron en cada caso, en las intervenciones en el Chaco en el período 1964-1972 hemos identificado a las localizaciones y los principales referentes, dado que contamos con la autorización de los mismos; mientras que en las acciones educativas iniciadas en 1995 en la provincia de Buenos Aires, hemos conservado el anonimato de los lugares e interlocutores.","palabras_clave":"organizaciones religiosas|qom|cultura escrita"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":177963,"idioma_id":5,"titulo":"Asteraceae, Mutisieae,  Holocheilus, Mutisia, Schlechtendalia, Panphalea, Perezia, Trichocline","resumen":"Flora Rioplatense: Sistemática, ecología y etnobotánica de las plantas vasculares rioplatenses","palabras_clave":"FLORA RIOPLATENSE|ASTERACEAE|MUTISIEAE"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":177964,"idioma_id":5,"titulo":"Asteraceae, Eupatorieae, Chromolaena","resumen":"Flora Rioplatense: Sistemática, ecología y etnobotánica de las plantas vasculares rioplatenses","palabras_clave":"FLORA RIOPLATENSE|ASTERACEAE|EUPATORIEAE|CHROMOLAENA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":178784,"idioma_id":5,"titulo":"Constitucionalismo Social","resumen":"El artículo indaga sobre la géness yvisiónactual del Constitucionalismo Social","palabras_clave":"CONSTITUCIONALISMO|ESTADO|LIBERALISMO|LUCHA OBRERA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":180027,"idioma_id":5,"titulo":"Comunidad textual en la red: el caso de los reconocimientos comentativos de ?Ningún historiador nace chorro?","resumen":"En el capítulo, que cierra el libro, se efectúa el análisis de los reconocimientos comentativos sobre textos, rumores y ?mitos? grupales, que tienen lugar en una comunidad de Facebook: ?Ningún historiador nace chorro?, con la pretensión de ilustrar las dimensiones de negociación del sentido y de cooperación interpretativa que se dirimen en la interacción y el seguimiento de los mensajes publicados en el sitio.   El caso, que supone el aprovechamiento de las posibilidades comunicativas de la plataforma para reunir y diversificar la conversación social alrededor de un conjunto de intereses académicos y de ocio de un amplio grupo de usuarios universitarios, fue creado en agosto de 2011, por tres estudiantes de Historia de la Facultad de Filosofía y Letras de la Universidad de Buenos Aires, Argentina, y, a partir de su paulatina popularidad, ha ido sumando alrededor de 35 mil seguidores.","palabras_clave":"RETOMAS|MEDIOS|DISCURSOS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":181715,"idioma_id":5,"titulo":"'Romanticismo'","resumen":"El capítulo realiza una presentación de los aspectos más significativos del período romántico.","palabras_clave":"PERIODIZACIÓN LITERARIA|ROMANTICISMO|RASGOS DISTINTIVOS|OBRAS CANÓNICAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":181716,"idioma_id":5,"titulo":"'Realismo'","resumen":"El capítulo presenta los aspectos más representativos del realismo como movimiento literario.","palabras_clave":"PERIODIZACIÓN LITERARIA|REALISMO|RASGOS DISTINTIVOS|OBRAS CANÓNICAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":181717,"idioma_id":5,"titulo":"'Naturalismo'","resumen":"El capítulo presenta los aspectos más representativos del naturalismo como movimiento literario.","palabras_clave":"PERIODIZACIÓN LITERARIA|NATURALISMO|RASGOS DISTINTIVOS|OBRAS CANÓNICAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":183536,"idioma_id":10,"titulo":"Tempo","resumen":"La noción de tiempo tiene en la sociología antropológica de Pierre Bourdieu una centralidad que ha sido poco puesta en evidencia. Es, por otra parte, uno de los conceptos que mejor permite ver la vinculación de su obra con la fenomenología husserliana, así como sus rupturas.","palabras_clave":"PIERRE BOURDIEU|TIEMPO|HUSSERL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":184988,"idioma_id":5,"titulo":"Las casas del sol naciente. Arqueología de la vertiente oriental de El Alto","resumen":"En este trabajo presentamos un panorama general sobre los avances de nuestras investigaciones en la vertiente nordeste de la sierra de El Alto-Ancasti, realizadas con una visión anclada en la zona que aborda los paisajes sociales en las diversas materialidades, prácticas y procesos que allí tuvieron lugar. El área de estudio, que comprende gran parte del Dto. El Alto (Catamarca), ofrece a la vez muchas posibilidades de análisis aunque pocos antecedentes arqueológicos. Si bien presentamos resultados sobre sus principales ambientes (pastizales de altura, yungas y arbustales del Chaco semiárido) en esta oportunidad centramos nuestra atención en las tierras altas de la sierra. Para su abordaje implementamos herramientas propias de la Arqueología del Paisaje integradas con Sistemas de Información Geográfica y con análisis específicos de arte rupestre, arquitectura y otras materialidades. Los resultados obtenidos apuntan a definir la existencia de comunidades agrarias, que habrían sido autosuficientes, económica y políticamente autónomas de otros ámbitos de ocupación en los valles occidentales con los cuales, sin embargo, habrían tenido lazos de interacción durante la segunda mitad del Primer Milenio.","palabras_clave":"Sierra El Alto-Ancasti|Arqueología del Paisaje|Pastizales de altura|SIG"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":185741,"idioma_id":5,"titulo":"Geografías imaginadas. Pensando la colonización española de la costa oriental patagónica (siglo XVIII) en el contexto regional.","resumen":"El proyecto Arqueología Histórica en Península de Valdés, Chubut (1779-1810)? , se inició en 2009 con el fin de abordar el poblamiento español de la costa patagónica, desde una perspectiva integrada entre la historia y la arqueología; específicamente, se centra en el Fuerte San José ? localizado en la actual Península Valdés. Pese a que el foco en un asentamiento particular, las investigaciones se proponen justamente, vincular el proceso de colonización de la costa con el resto de la región patagónica. La conformación del paisaje colonial en Península Valdés se indaga a partir de la puesta en práctica de los establecimientos españoles, los cuales son resultantes de la articulación histórica de relaciones sociales, económicas y políticas específicas, originadas por la expansión europea sobre la región y sobre sus poblaciones nativas.   Esta perspectiva crítica implica que el relato histórico deja de lado la concepción atlántica que lo circunscribe a la línea costera para integrar  los procesos ocurridos en la costa con los del interior patagónico y del área transandina. Esto lleva a cuestionar la funcionalidad defensiva de los asentamientos y  la homogeneidad regional asumida tanto a nivel social como geográfico. A su vez, en la compleja red de producción e intercambio coloniales, se integra a las poblaciones indígenas como agentes activos; finalmente se busca comprender el paisaje, no ya como mero telón de fondo, sino como una dimensión más del cambio social a través del cual se entretejen las redes sociales, políticas y económicas.","palabras_clave":"COLONIALISMO|PATAGONIA| SIGLO XVIII|RELATOS MAESTROS|ESPACIALIDAD"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":185881,"idioma_id":5,"titulo":"Alfabetización y evangelización: una mirada comparada acerca de propuestas educativas hacia los qom en el marco de congregaciones religiosas","resumen":"La participación de las congregaciones religiosas en la educación indígena en la Argentina ha adquirido distintas formas a lo largo de la historia, incidiendo tanto las doctrinas y estrategias de intervención de los distintos credos como las políticas estatales, la región y el colectivo étnico implicados. Especialmente desde el siglo XIX, los qom fueron objeto de acciones específicas por parte de misioneros que, en localizaciones urbanas y rurales del Chaco, articularon de distinto modo la evangelización y la alfabetización en español.   Teniendo en cuenta estos antecedentes, este trabajo se propone comparar dos intervenciones en la historia reciente: la acción misional en la ciudad de Castelli por parte de religiosos protestantes entre 1964 y 1972, y la escolarización en un Barrio Toba del Gran Buenos Aires por parte de una congregación católica, desde 1995 hasta el 2006. En la comparación es necesario advertir dos dimensiones claves que permiten profundizar el sentido de las diferencias: una de ellas es que la experiencia de Castelli se dio en un marco misional de educación no formal, destinada a niños, jóvenes y adultos, mientras que la del GBA se desarrolló dentro de una escuela primaria. La segunda dimensión a considerar es el de los diferentes contextos históricos en que se producen ambas propuestas.","palabras_clave":"Alfabetización|Evangelización|Formación moral|Educación intercultural"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":186014,"idioma_id":5,"titulo":"Geometría","resumen":"Contenido teórico y práctico de los temas de Geometría para desarrollar el dictado del curso de ingreso para alumnos aspirantes a ingresar a carreras de Ingeniería, Tecnicaturas y Arquitectura del Departamento de Ingeniería e Investigaciones Tecnológicas de la Universidad Nacional de La Matanza.Incluye movimientos en el plano, Semajanza, Trigonometría y cuerpo geometricos.Contiene Link a materiales interactivos","palabras_clave":"GEOMETRÍA|INGRESO|INGENIERÍA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":186202,"idioma_id":4,"titulo":"Antarctic archaeology: Revising the history of the Southernmost end of the world","resumen":"Antarctica was the last continent to be known. Human encounters with the region acquired different characteristics over time. Within the framework of dominant narratives, the early 'exploitation' of the territory was given less attention than late nineteenth-early twentieth-century 'exploration'. Nineteenth-century exploitation was especially associated with sealing on the South Shetland Islands. Dominant narratives on the period refer to the captains of sealing vessels, the discovery of geographical features, the volume of resources obtained. However, they do not consider the life of the ordinary sealers who lived and worked on the islands. In this chapter we will try to show the power of archaeology to shed light on these 'invisible people' and their forgotten stories. We hold that archaeology offers a possibility for reimagining the past of Antarctica, calling for a revision of traditional narratives.","palabras_clave":"Antarctica|archaeology|history|invisible people"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":186330,"idioma_id":5,"titulo":"Tenemos la fuerza que nos da la comunidad, la organización. Resistencia indígena, escuela media y trabajo docente en el Chaco (1994-2010)","resumen":"En este capítulo, sus autoras proponen analizar el proyecto intercultural que tiene lugar en una escuela media de la provincia del Chaco, el Bachillerato Libre para Adultos Bilingüe Intercultural, destinado a jóvenes y adultos qom, que funciona desde 2001 en Pampa del Indio .  Consideran que constituye un contexto inédito -desconocido, nuevo   - para los profesores y las profesoras de las escuelas medias de la provincia. La vinculación de su origen y su desarrollo con las actuales dinámicas étnicopolíticas de organizaciones indígenas que confrontan con el Estado por tierras, cultura y reconocimiento político (Bartolomé, 2005; Guarino, 2008\/2012 y 2010) ponen en cuestión rasgos estructurales de la escuela media argentina. Da lugar a un proyecto intercultural que interpela las dimensiones política, epistemológica, cultural y educativa del trabajo docente; que tensa y cuestiona los modos tradicionales de organización, gobierno y gestión institucional, de selección de los docentes, de organización y desarrollo del currículum, de relación entre la escuela media y las comunidades en las que está inserta. El trabajo principia con una historia de la educación bilingüe intercultural (en adelante EBI) que comenzó en el Chaco en 1987. La profundidad y extensión otorgada a la misma obedece a la necesidad de conocer el estado de situación de la EBI y  los procesos que se desarrollan en la mediana duración. Entendemos que permiten comprender más acabadamente el caso que nos ocupa porque lo liga con la situación socio-educativa de los Qom y las carencias de la política de la EBI en el Chaco, entre las que se destacan la falta de propuestas de Nivel Medio y un desarrollo de la normativa de carácter contradictorio, asincrónico y con vacíos que afectaron particularmente el trabajo de los docentes indígenas. Se procede luego a analizar el programa educativo del que ese Bachillerato es parte y que fue gestado por una organización indígena, el Consejo Qompi de Pampa del Indio, con el apoyo de organizaciones no indígenas a partir de 1994. Se reconstruye la génesis del proyecto y se señalan las propuestas de formación que incluye. Posteriormente se caracteriza el Bachillerato Libre para Adultos Bilingüe Intercultural (en adelante BLA). Se examinan situaciones que ponen en evidencia procesos de apropiación de la escuela media por parte de la organización qom y configuraciones y sentidos de la escuela y del trabajo docente que cuestionan y trasmutan rasgos habituales. Los testimonios, las voces de docentes y miembros de la organización qom y de la organización no indígena nos permiten escuchar los sentidos que otorgan al proceso en el que están inmersos y el análisis que hacen de las relaciones con el Estado provincial en el período que transcurre entre 1994 y 2010 ?cuando ya habían comenzado cambios en la política provincial para los pueblos indígenas que exceden este trabajo  . A la vez, esos mismos testimonios y los documentos de su autoría nos permiten profundizar en los procesos de apropiación de recursos culturales (Rockwell, 2004-2005) y en los procesos de construcción de autonomía escolar impulsada desde abajo (Feldfeber, 2009; Pini, 2009),  vinculada a colectivos indígenas que tienen un horizonte de lucha por derechos que incluyen, pero que no se reducen al ámbito escolar. La perspectiva teórica sobre interculturalidad en educación que sustenta el análisis considera las históricas relaciones antagónicas de pueblos indígenas con el Estado (Bartolomé, 2005) y se apoya en la noción de un proyecto intercultural, en tanto ?procesos y prácticas situadas sociohistóricamente que configuran y se configuran en un campo de disputa; en el que existen correlaciones de fuerza variables entre diversos actores con diferentes ?y frecuentemente opuestos- intereses. Están presentes en esa construcción: las formaciones, estructuras y resistencias; las relaciones de desigualdad social y la lucha para transformarlas? (Grimberg, 2003 y Walsh, 2002 citado en Diez, 2004:195). Es ésta una conceptualización potente cuyo correlato empírico se encuentra ?sostenemos- en este caso en estudio. Las fuentes y procedimientos de relevamiento de información consistieron en entrevistas en profundidad a docentes indígenas ?uno de los cuales es miembro del Consejo Qompi- y a integrantes de la organización no indígena Che?Eguera que acompaña el proyecto desde sus comienzos. Asimismo, entrevistas grupales a docentes no indígenas, observaciones en terreno (reuniones y talleres), análisis de documentos elaborados por integrantes del proyecto y consulta de estadísticas educativas, datos censales y normativas provinciales y nacionales. El trabajo que se presenta no agota los temas que aborda y deja afuera niveles y aspectos de análisis. Pretende constituir un aporte parcial a la comprensión de un proceso específico de construcción de lo intercultural y de las transformaciones que el mismo supone para las configuraciones y significados del trabajo docente.","palabras_clave":"ESCUELA MEDIA|TRABAJO DOCENTE|DOCENTES INDÍGENAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":186526,"idioma_id":4,"titulo":"A Brief History of Production and Labour of a State-owned Enterprise: A Case Study of an Argentinean Shipyard, Astillero Río Santiago","resumen":"With a regulatory protectionist framework promoting the construction of ships in the country, the development of the shipbuilding industry in Argentina was characterized by strong State intervention. The State had an important participation in supply, being the owner of large shipyards, and also in demand for ships for the Argentinean Navy and for the country?s main transport and production companies, constituting an important public, productive, and commercial framework.   The characteristics of the Argentine shipbuilding industry, its recent history and the role of the State are not the focus of this chapter: a case-perspective approach is adopted to observe how macro-social processes (changes in capitalism and in the organization of production, and the economic role of the State) are expressed at a micro-social level, in this case, at company level. The aim of this chapter therefore, is to characterise several dimensions of Argentina?s largest and most significant state-owned shipyard: Astillero Rio Santiago (ARS) and to highlight the most significant developments in production, employment, working conditions and industrial relations at the shipyard in the last five decades.    The chapter is divided into five parts. First, I trace the history of the enterprise, as well as its relationship with the National Industrial Policy and the role of the State. Second, I describe the characteristics of production, technology and organization of labour present in the shipyard, and identify the changes that occurred in the last few decades. Third, the characteristics of workers in ARS are analysed, their working conditions, and the features of the internal labour market. Fourth, and in relation with the previous topic, I describe the specific work culture built around the shipyard, highlighting the material and symbolic (values, visions, norms, beliefs, symbols) aspects which supported it. Fifth, I will analyse the recent history and current characteristics of labour relations in the company. I will also focus on two key points in the history of labour disputes in the shipyard: the strategies of workers during the last military dictatorship in Argentina (1976?82) and the struggles of resistance faced in the 1990s privatization onslaught. Finally, I reflect upon developments in the company, remarking on the current organizational and productive challenges, and the place that social actors (especially unions) have within the enterprise.","palabras_clave":"SHIPBUILDING|GLOBAL LABOUR HISTORY|WORKERS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":186720,"idioma_id":4,"titulo":"The shift to 'modern' and its consequences: changes in property rights and wealth distribution in Buenos Aires, 1839-1914","resumen":"        From 1839 to 1914, rural areas of Buenos Aires experienced  significant changes. They included the transformation of old rights on land  access, and the settling up of new or ?modern? property rights, granted by  specific government offices. Through a sample case, this paper is trying to  evaluate the impact of these changes in land prices (which rise at a pace often  double than other production factors), and how that rise affected wealth  distribution. All the period is scored by fast economic development, shifting  from extensive cattle production to sheep farming and then to commercial crops.  But, if this development asserted increases in the proportion of landowners on  total population, at the same time inequality between owners grew, or did not  declined substantially. As our case study shows, capital investment that took  place since 1881, with the new system of property rights in full force, was a  contributing factor to hold up inequality. But, the peak of inequality was  reached through the previous period, when new property rights were settled up. If  conclusions are not to be generalized, in any case they show a new approach to  the effects of ?modern? property rights in a context of fast rural growth.  ","palabras_clave":"PROPERTY RIGHTS|WEALTH DISTRIBUTION|AGRICULTURE|PAMPAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":186832,"idioma_id":5,"titulo":"Geologia de la costa marina bonaerense","resumen":"GEOLOGÍA DE LA COSTA MARINABONAERENSESilvia Cristina Marcomini y Rubén Alvaro LópezDepartamento de Geología, Facultad de Ciencias Exactas y Naturales, Universidad deBuenos Aires. scm@gl.fcen.uba.arMORFOESTRUCTURALa forma y evolución de la costa de Buenos Aires está relacionada con la morfología y estructuras que posee el subsuelo en profundidad y las geoformas superficiales presentes en la actualidad.La provincia de Buenos Aires está integrada por una extensa llanura compuesta por sedimentos cenozoicos interrumpida por dos cordones serranos: las sierras Septentrionales y Australes (Figura 1). Las primeras, también denominadas Tandilia, constituyen un cordón alineado en sentido noroeste-sudeste con una altitud no mayor de 530 m, cuyos afloramientos se extienden hasta Cabo Corrientes, en la ciudad de Mar del Plata.Su estructura se continúa hacia la plataforma continental. Estas sierras son discontinuas y se dividen en dos grupos orográficos: sierra de Olavarría y sierras de Balcarce.Las rocas más antiguas del país afloran en Tandilia.Las sierras Australes o Ventania constituyen una estructura en arco, donde se destacael Cerro Tres Picos que alcanza una altitud de 1.247 m.El subsuelo de la provincia de Buenos Aires presenta tres cuencas sedimentarias principales,que se extienden hacia la plataforma continental. Las mismas están separadaspor dorsales del basamento que forman subcuencas o depocentros aislados. Estascuencas, si bien son muy antiguas, en muchos casos han controlado la evolucióncostera durante el Neógeno. Entre las cuencas principales que se extienden hacia laplataforma continental se distinguen (Figura 1):Cuenca del Salado: Tiene forma elongada y se ensancha hacia el sudeste donde intersecta el margen continental. Un 40 % de su superficie se extiende en el ámbito marino.Limita hacia el norte con el umbral de Martín García y hacia el sur con la escarpa de Tandilia. El relleno estimado por estudios sísmicos es de 7.000 m de sedimentos mesozoicos y cenozoicos. Sobre esta cuenca se ha desarrollado la unidad morfológica conocida como Pampa Deprimida (Tricart, 1973).Cuenca de Claromecó: Se extiende entre los cordones de Tandilia y Ventania. Setrata de una cuenca asimétrica de forma oval con varios miles de metros de relleno,especialmente con unidades del Paleozoico superior. A nivel geomorfológico se ladenomina Pampa o Llanura Interserrana (Frenguelli, 1950).Cuenca del Colorado: Limita hacia el sur por el borde norte y la extensión marítimadel Macizo Norpatagónico, hacia el noreste con la sierra de Ventania y hacia eleste con la denominada ?Cuenca Argentina? con profundidades mayores a los 1.000m. Está integrada por una secuencia tectonoestratigráfica precámbrica-paleozoica de prerift, una Jurásica superior-Cretácica inferior de sinrift y una etapa final de margen pasivo (Cingolani, 2005).En el sudoeste de la provincia de Buenos Aires se encuentra en profundidad y no aflorante, el Macizo Norpatagónico, constituido por rocas del Precámbrico-Paleozoico inferiory del Permo-Triásico","palabras_clave":"GEOLOGIA|ECOLOGIA|AMBIENTE"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":187125,"idioma_id":4,"titulo":"Macrocyclic lactones: endectocide compounds","resumen":"General pharmacology: avermectins and milbemycinsMechanism of action: ecto-endoparasiticidal activityPharmacokinetics  -Exchange between bloodstream and target tissues  -Metabolism. Bile and intestinal excretion. Involvement of drug   transport systems. Pharmacokinetic-pharmacodynamic relationshipTherapeutic uses: animal species-specific considerationsResistanceAvailable pharmaceutical preparationsDrug and host-related factors affecting pharmacokinetics and efficacy in ruminantsTissue residues. Withdrawal timesSafety and toxicityEcotoxicological impactConcluding remarks","palabras_clave":"Macrocyclic lactones|endectocide compounds"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":187133,"idioma_id":5,"titulo":"La construcción discursiva del desaparecido en Clarín. Avatares de una figura (1975-1981)","resumen":"La desaparición forzada de personas constituyó la metodología fundamental del plan represivo coordinado e instrumentalizado por las Fuerzas Armadas (en adelante FFAA) durante la última dictadura militar en Argentina. El ocultamiento de las evidencias y la dificultad para identificar a los responsables, así como la disminución de los costos políticos que, a corto plazo, implicaba la desaparición frente al asesinato público, la convirtió en la técnica represiva elegida por excelencia (Novaro y Palermo, 2006; Aguila, 2008). No obstante, a pesar de la sistematicidad y organización con la que operó el poder desaparecedor (Calveiro, 1998), las consecuencias no deseadas del crimen no tardaron en salir a la luz pública. Como se busca demostrar en estas páginas, las desapariciones se constituyeron en protagonistas cada vez más predominantes de la crónica periodística diaria y su figura emblemática, la del desaparecido, se ubicó en el centro de complejos y contradictorios procesos de construcción discursiva que le permitieron ir desde las sombras en las que intentó recluirlo el Terrorismo de Estado hacia una visibilidad mediática producto de la incansable lucha del movimiento de derechos humanos, pero también, de las respuestas que debió ensayar el régimen ante las incesantes protestas.","palabras_clave":"Pasado reciente|dictadura militar|violencia política"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":187490,"idioma_id":5,"titulo":"El régimen internacional de la tutela, curatela e instituciones análogas","resumen":"La tutela y la curatela son institutos cuyo principal objetivo radica en asegurar la protección de menores e incapaces.  Al adentrarnos en la regulación de estos institutos a nivel internacional, los diversos ordenamientos jurídicos han adoptado diversos criterios para la atribución de competencia, como a fin de establecer el derecho aplicable.  De este modo, en relación a la determinación del juez competente a los fines de entender en estos supuestos, diversos son los sistemas entre los que pueden optar las legislaciones. Entre ellos, podemos encontrar aquellos que determinan que el mismo será:   - El de la nacionalidad del incapaz.   - El del domicilio del incapaz.   - El de la residencia del incapaz.   De manera coincidente, en materia de derecho aplicable diversas son las opciones que nos ofrecen las diferentes normativas elaboradas a los fines de regular la materia que nos incumbe. Así, nos encontramos con que la tutela y curatela podrán ser regidas por:   - La ley del domicilio del incapaz.   - La ley de la nacionalidad del incapaz   - La 'lex fori'.  -Sistema mixto, donde rige la ley del domicilio o de la nacionalidad para lo atinente a la persona, mientras que las cuestiones relativas a los bienes serán regidas por la del lugar de situación de los mismos.   Estos institutos no poseen gran desarrollo en la legislación interna, al menos en lo que respecta al Derecho Internacional Privado. Por lo que se considera pertinente profundizar el estudio y desarrollo de esta problemática que no deja de ser importante en relación a la protección internacional de la minoridad.  En razón de ello, realizaré un abordaje de los temas reseñados, comenzando por su desarrollo en nuestra fuente interna, continuando luego por la fuente convencional, pasando a posteriori por los diversos proyectos de reforma, la diversidad de regulaciones previstas a nivel del derecho comparado, coronando con la jurisprudencia existente en la materia.","palabras_clave":"TUTELA INTERNACIONAL|CURATELA INTERNACIONAL|RESPONSABILIDAD PARENTAL|FILIACION INTERNACIONAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":187491,"idioma_id":5,"titulo":"LA ADOPCIÓN INTERNACIONAL EN EL MARCO DE UN DESASTRE NATURAL. ?G. S. M. s\/ exequátur (inscripción de partida extranjera - adopción y acciones vinculadas)?, 2 de Agosto de 2010","resumen":"La adopción se erige ante nosotros como una de las temáticas más fascinantes y relevantes en materia de minoridad.   En primer lugar, es dable tener presente que se entenderá por adopción internacional aquella en la que estamos en presencia de elementos extranjeros.   Estos elementos extranjeros estarán dados por la falta de coincidencia de domicilio y\/o residencia habitual entre adoptantes y adoptado. En consecuencia, estaremos frente a un supuesto de adopción internacional cuando 'el domicilio de los adoptantes se encuentra en un país distinto al lugar donde el adoptado tiene su domicilio o residencia habitual.'   El presente comentario versa, precisamente, sobre la cuestión anteriormente reseñada, pero constituida en el marco de una situación especial: una catástrofe natural.   En tal sentido, se nos presentará una nueva forma de estudiar la materia, con algunas visiones novedosas, pero conservando como criterio basal la prevalencia del interés superior del niño.   En el mismo se describirá el pedido de una madre adoptiva conforme sentencia extranjera, de la que se solicita su reconocimiento, como así también su conversión en adopción plena y la adición de un segundo nombre para el menor.","palabras_clave":"ADOPCION INTERNACIONAL|INTERES SUPERIOR DEL NIÑO|CATASTROFE NATURAL|COOPERACION INTERNACIONAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":187492,"idioma_id":5,"titulo":"EL DERECHO DE VISITAS VIRTUAL. ?FS C\/ CE S\/ Régimen de Comunicación?, 30 de Diciembre de 2008","resumen":"El derecho de visitas es una problemática cuyo tratamiento no ha sido profusamente abordado, en contraposición con lo que sucede en otras materias relacionadas con la minoridad como la filiación y la adopción, entre otras.   Este instituto es definido por la más autorizada doctrina no sólo local, sino también por la internacional, como 'el derecho que permite el contacto y comunicación permanente entre padres e hijos, permitiendo el desarrollo afectivo, emocional y físico, así como la consolidación de la relación paterno filial. Jurídicamente, visitar implica estar, supervisar, compartir, responsabilizarse; por tanto, resulta más conveniente referirnos, de manera integral, al régimen de comunicación y de visita.  En el presente comentario, no sólo me abocaré al estudio de esta cuestión, sino que adelanto que el fallo dispondrá la interconexión de la misma con la máxima expresión de la modernidad, materializada en la posibilidad de mantener un 'régimen de visitas virtual'.","palabras_clave":"DERECHO DE VISITA|RESPONSABILIDAD PARENTAL|MENOR|REGIMEN COMUNICACION VIRTUAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":188195,"idioma_id":5,"titulo":"'Conformación y dinámica de los ministerios 'políticos' del gabinete nacional. El Ministerio del Interior y la Jefatura de Gabinete a través de sus miembros jerárquicos (1983-2007)'","resumen":"Los distintos ministerios que componen el gabinete nacional recortan dominios de intervención específicos, se relacionan con diversos conjuntos de interlocutores y se componen de elencos relativamente diferentes entre sí. Hemos mostrado en otras investigaciones que la confianza personal del presidente, la expertise y el arraigo o los soportes organizacionales externos tienen mayor o menor importancia para explicar la designación y permanencia de los ministros según el tipo de cartera de que se trate: económico, social o político (Gené, Heredia y Perelmiter, 2014).   En este trabajo caracterizamos a los dos principales ministerios de intermediación política que componen el gabinete, el Ministerio del Interior y la Jefatura de Gabinete de Ministros. Con historias institucionales particularmente distintas ?el primero de ellos existe desde que se constituyó el Estado nacional, mientras que la Jefatura de Gabinete fue creada hace apenas diez años, con la reforma constitucional de 1994- dichos ministerios han tendido a solaparse en algunas de sus funciones y principales responsabilidades en la estrategia del gobierno nacional durante los últimos años. El presente artículo analiza la conformación de sus elites dirigentes, tipifica sus trayectorias y capitales, y avanza hacia una comprensión de sus dinámicas de funcionamiento. Se inscribe, así, a la vez en la creciente literatura sobre gabinetes en América Latina y en el programa de sociología de las elites que nuclea a los autores del libro.","palabras_clave":"ELITES|MINISTERIOS|POLITICA|ARGENTINA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":188256,"idioma_id":5,"titulo":"Patogénesis Bacteriana","resumen":"Los editores no solicitaron resumen de este capítulo.","palabras_clave":"Patogénesis|Bacterias|Factores de Virulencia"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":188362,"idioma_id":5,"titulo":"Dignidad, responsabilidad, liberación. Reflexiones bioéticas sobre la muerte en el contexto de una legislación reciente","resumen":"La reciente 'Ley de muerte digna' 26742, aprobada en 2012, permite repensar nuestras actitudes, valoraciones y opciones relativas al buen morir. Este artículo se propone, en primera instancia, recuperar y problematizar algunas de las nociones filosóficas más influyentes al respecto. En segundo lugar, se analizan los principales elementos conceptuales en bioética contemporánea, en particular la noción de autonomía y dignidad, así como también sus consecuencias prácticas. A continuación se propone una interpretación de la muerte como posibilidad de dignidad. Luego se indagan los principales aspectos de la ley en cuestión, las opciones que abre, y los criterios para su justificación. Finalmente el texto propone una posición propia respecto del modelo filosófico y bioético de trabajo en el contexto latinoamericano: bioética de liberación y bioeticistas públicos.","palabras_clave":"BIOETICA|MUERTE DIGNA|AUTONOMIA|DIGNIDAD"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":188374,"idioma_id":5,"titulo":"Participación en redes transnacionales. Vinculaciones entre lo global y lo local en una cooperativa de cartoneros","resumen":"El objetivo de este articulo es analizar de que manera la participación en estos espacios se ha vuelto esencial tanto en relación con la construcción política de la cooperativa como para el acceso a recursos provenientes de ONGs y empresas que se vinculan con la Red Latinoamericana y del Caribe de Recicladores (Red LACRE), redefiniendo tanto ideas como concepciones de la cooperativa y sus dirigentes. Al mismo tiempo, los encuentros internacionales han potenciado el reconocimiento de la experiencia, tanto a nivel local como internacional, por diferentes organismos públicos como la Secretaría de Ambiente y Desarrollo Sustentable municipal o la Secretaría de Ambiente y Desarrollo sustentable de la Nacio&#769;n.","palabras_clave":"activismo transnacional|Cooperativas|Cartoneros"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":188382,"idioma_id":5,"titulo":"Modos de hacer y pensar colectivamente. Reflexiones en torno a las formas de participación y ?compromiso? a partir de dos casos etnográficos","resumen":"Este artículo presenta algunos de los resultados de nuestras tesis de licenciatura y sintetiza una serie de reflexiones que mantuvimos en el marco del proyecto de investigación del que formamos parte desde una preocupación compartida centrada en el análisis de las formas de participación en diversos espacios de organización colectiva.  Recuperamos aquí nuestro trabajo de campo realizado con una radio ?comunitaria y popular?  creada en el marco de una fábrica recuperada por sus trabajadores y con una organización no gubernamental que gestiona préstamos para cooperativas de trabajo. Desde un enfoque etnográfico nos interesa comparar el modo en que las personas que integran estos espacios experimentan y significan su participación. en este trabajo nos proponemos comparar el modo en que en estas dos organizaciones que son definidas por sus integrantes como espacios de construcción política, el ?compromiso? es producido, actualizado, negociado y tensionado en  sus relaciones y prácticas cotidianas. Siguiendo a Elías (1990) entendemos que el ser humano individual está siempre y completamente inmerso en relaciones con otros y que el trato con otras personas produce en el individuo ideas, convicciones, afectos y necesidades en un tejido de relaciones caracterizado por un continuo dar y recibir. Partiendo de estas relaciones de ?encadenamiento? e ?interdependencia? que producen al individuo como tal (Elías, 1990) en este artículo buscaremos analizar las modalidades de participación de las personas en espacios de organización colectivos dando cuenta del modo en que se producen obligaciones recíprocas. En este sentido sostenemos que sentirse obligado a (hacer) y con (otros), es decir, esas obligaciones recíprocas deben ser pensadas en el marco de relaciones de interdependencia que son condición de posibilidad de la producción y reproducción de esos espacios de construcción política.","palabras_clave":"Formas de participación|procesos de organización colectiva|Antropología Política"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":188449,"idioma_id":5,"titulo":"La documentación de prácticas lingüísticas emergentes en situación de desplazamiento lingüístico: 'hablar idioma' entre los jóvenes tapietes de Argentina","resumen":"Como respuesta a la creciente preocupación por la rápida desaparación de las lenguas minoritarias en el mundo, la lingüística de la documentación se ha propuesto el registro de corpora representativos de las lenguas y sus distintos usos que se buscan documentar con multiples propósitos. Muchos proyectos de documentación han privilegiado el registro de los usos y formas de las lenguas que pertenecen al pasado de una comunidad y se encuentran en retroceso con el fin de dejar registros de aquello que representa cierta 'tradición' cultural y lingüística que puede dejar de existir en el futuro. Este trabajo se propone, en cambio, reflexionar sobre la importancia de considerar todas las formas contemporáneas del habla presentes en una comunidad que atraviesa procesos de desplazamiento avanzado de la lengua originaria por el español, a la vez que lleva adelante actividades de revitalización lingüística. A partir de un repaso de distintas tradiciones y propuestas de la lingüística de la documentación y desde un enfonque crítico con respecto a la aproximación al fenómeno de desplazamiento lingüístico vinculado a la idea de ?muerte de lengua?, el objetivo de este artículo es describir el trabajo de relevamiento y documentación de prácticas emergentes del tapiete en hablantes jóvenes de Argentina que tienen el español como lengua primera; un tipo de trabajo menos presente en los programas de documentación. Asimismo, el artículo retoma el debate sobre la necesidad de vincular los proyectos académicos y los comunitarios como requerimiento necesario para las posibilidades de desarrollo de los primeros.","palabras_clave":"Documentación lingüística|Desplazamiento lingüístico|lengua tapiete (tupí- guaraní)|Hablantes jóvenes"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":188450,"idioma_id":5,"titulo":"La lingüística de la documentación y las lenguas amenazadas: de los ejes fundacionales a las experiencias colaborativas en América del Sur","resumen":"La documentación lingüística, ligada al trabajo de campo con comunidades de habla y a la recolección de los datos in situ, ha sido una práctica central desde el principio de la lingüística como ciencia, tanto en Europa como en América del Sur. Sin embargo, la lingüística de la documentación, tal como se la reconoce actualmente, surgió en la década de los noventa. El objetivo de esta disciplina es la creación de registros de las lenguas del mundo y de sus patrones de uso, orientándose su tarea especialmente hacia la anotación de tales recursos del lenguaje, su preservación en formatos durables y su difusión. En este capítulo nos proponemos, a modo de introducción,  trazar las trayectorias y ejes centrales de la LD desde su surgimiento hasta la actualidad. En este sentido, por un lado, presentamos los debates e ideas fundantes de esta disciplina a nivel internacional. Por otra parte, vinculamos estos antecedentes con las prácticas concretas de investigación y acción en América del Sur.","palabras_clave":"Lingüística de la documentación|Lenguas amenazadas|Textos fundacionales|Proyecciones"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":188819,"idioma_id":10,"titulo":"Las políticas migratorias regionales y los derechos de los trabajadores","resumen":"Se analizan las migraciones  y sus perspectivas  desde la  visión hegemónica y la perspectiva alternativa  de la región suramericana y los ámbitos en que ésta última se viene construyendo.  Se evalúa el tratamiento de la cuestión en el MERCOSUR , sus avances y limitaciones poniendo especial énfasis en los órganos sociolaborales   del espacio de integración regional y la necesidad de adecuación a las políticas migratorias regionales.","palabras_clave":"derecho del trabajo|migraciones"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":189231,"idioma_id":4,"titulo":"The Place for Morality in Law: An Exchange Between Robert Alexy and Joseph Raz","resumen":"There is a recurrent debate in legal theory related to which is the best way to understand law. Many prominent legal theorists maintain that it is crucial to understand law to determine whether there is a necessary relation between law and morality. Robert Alexy is one of them.  All his writings from the very beginning were surrounded by this idea.  In this paper I want to highlight how sharing the idea that there is a necessary connection between law and morality stimulates the discussion about the better way to understand law, rather than to put an end to it. Robert Alexy and Joseph Raz are the authors I have chosen to make this point. Although they coincide that to understand what law is it is necessary to understand a moral value, they explain this moral value differently. Their different understanding of the moral value to which law is necessarily bounded has (in principle) big impact. They determine their view of how to identify normative dispositions that integrate legal systems, as well as their practical force.","palabras_clave":"RAZONAMIENTO JURIDICO|RAZONAMIENTO JUDICIAL|INTERPRETACION JURIDICA|ALEXY"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":189849,"idioma_id":5,"titulo":"«Sicut cancer, amplius serperet in occulto». La herejía oculta en el derecho bajomedieval y tempranomoderno","resumen":"La tendencia a la visibilización de lo oculto que destila la cultura bajomedieval puede ya detectarse en textos fundadores de la legitimación de la persecución como en la decretal de Inocencio III Vergentis in senium en la que se asimila la herejía con el crimen de lesa majestad y donde se califica a la herejía como una peste mortífera que no se ha podido aniquilar ni evitar que se extienda ?in occulto? como un cáncer. Llegará un momento en que los manuales de inquisidores incluirán casi de rigor una quaestio de haeresi occulta. Pero esta normalización supone una historia cuyo desarrollo se debe cartografiar vinculándolo a la dinámica de la war on heresy (al decir de Robert Moore), de la construcción ?jurídico-política? de mecanismos de poder en Europa occidental, de las transformaciones intelectuales de la Baja Edad Media, etc. En este trabajo, exploramos esta cuestión, abordándola desde tres flancos. En primer lugar, intentamos captar un momento de formación de la noción de herejía oculta a partir del análisis de un desacople detectable entre el texto del Decretum de Graciano y su Glosa Ordinaria. En segundo lugar, procedemos a examinar una categoría distinta pero paralela y fuertemente relacionada en nuestra perspectiva, como es la del credens, uno de los subtipos de los fautores haereticorum que la legislación canónica condena en sucesivos concilios como parte del plan de erradicación de la herejía. Por último, planteamos unos interrogantes en torno del caso extremo del haereticus omnino occultus: la idea de una herejía totalmente oculta, de naturaleza únicamente mental, constituye un caso límite que suele generar debate, tensiones sémicas y paradojas y cuyo análisis obliga a contemplar las modalidades de la casuística medieval.","palabras_clave":"DERECHO MEDIEVAL|HEREJIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":189850,"idioma_id":5,"titulo":"Entre el museo y el taller: recorriendo itinerarios jurídicos del pasado","resumen":"Introducción a compilación de trabajos sobre historia del derecho medieval","palabras_clave":"DERECHO MEDIEVAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":189967,"idioma_id":5,"titulo":"Política y trincheras. Los pueblos en la organización del ?Ejército Federal´ del Sitio a la ciudad de Buenos Aires, diciembre de 1852-febrero de 1853","resumen":"El presente trabajo analizará el proceso de militarización y la crisis general que provocó en Buenos Aires el denominado ?Sitio de Lagos?. Nuestra propuesta es avanzar en el análisis de la rebelión con una mirada que incluya el estudio del Sitio en el marco de las actitudes y estrategias de los pueblos en tiempos de guerra. La movilización implicó levas, contribuciones y afiliaciones de los pueblos del interior de la provincia de Buenos Aires tanto para un bando como para otro. También motines, deserciones y otras formas de resistencia al enrolamiento. Puso en juego los criterios de legitimidad utilizados para defender las causas y generó una oleada de movilización que, ensamblada a los problemas provinciales, dan cuenta de variados aspectos de la vida política de estas sociedades. Particularmente, expresan lo dificultoso y agitado que fueron los años posteriores a la caída de Rosas y a la formación del Estado de Buenos Aires. Se analizan aquí los primeros dos meses del conflicto, momento en el cual se produce el cambio de autoridades y el enrolamiento, cuestión que genera caos en los pueblos.","palabras_clave":"GUERRA|SIGLO XIX|NACIÒN|MUNDO RURAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190257,"idioma_id":5,"titulo":"Impacto del volcanismo holocénico sobre el poblamiento humano del extremo noroeste de la Patagonia Argentina","resumen":"Para el extremo noroeste de la Patagonia Argentina, se ha debatido intensamente sobre la existencia de un período extenso de baja ocupación humana provocado por un aumento de la aridez, que abarcaría una parte importante del Holoceno medio. En este trabajo, se presentan los resultados de una investigación geoarqueológica diseñada para contrastar la posibilidad que haya sido el volcanismo una de las causas o la causa principal de esa posible caída demográfica reflejada en la disminución de registros arqueológicos para el lapso comprendido entre los años 7000 y 5000 AP. El estudio se desarrolló especialmente en La Payunia, uno de los campos volcánicos más importantes del planeta, ubicado en sureste de la provincia de Mendoza (Argentina). Se describen brevemente las características geomorfológicas y la extensión de una serie de eventos efusivos de retroarco, ubicados en el Holoceno mediante fechados directos por termoluminiscencia. Por otra parte, se articulan esos resultados con estudios referidos a volcanes de arco y con datos obtenidos de la caracterización química y fechado de lluvias de material piroclástico localizadas en sitios arqueológicos y en depósitos geológicos con la intención de relacionar el impacto de esos eventos sobre el ambiente y discutir las propuestas realizadas para explicar las discontinuidades temporales observadas en los registros arqueológicos de la región.","palabras_clave":"VOLCANISMO|HOLOCENO|ARQUEOLOGÍA|NORTE PATAGONIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190384,"idioma_id":5,"titulo":"De lazos familiares a redes sociales: nuevos aportes para la discusión de interacciones entre poblaciones de la Puna y las Tierras Bajas orientales.","resumen":"Si bien numerosas investigaciones arqueológicas han propuesto, a partir de la recuperación de bienes foráneos, la existencia de antiguas interacciones entre poblaciones que habitaron diferentes zonas geográficas, mucha menos atención ha recibido el análisis de las circunstancias que pudieron estar vinculadas con el traslado de los productos y\/o la naturaleza de las relaciones entabladas entre las personas que intervinieron en esos contactos. Es en el marco de la problemática de interacciones entre poblaciones geográficamente distantes que presentamos aquí un abordaje multidisciplinario que integró diversos enfoques y líneas de evidencia para el examen de un contexto funerario infantil y múltiple, recuperado en la microrregión de Antofagasta de la Sierra, NO de Catamarca. Dichos análisis abarcaron: aproximación arqueobotánica que incluyó la identificación taxonómica de macro y micro restos y discusión sobre su área de distribución natural, determinación composicional de cuentas minerales (DRX); análisis tecnológico y morfo funcional del contenedor cerámico (urna) y otros elementos asociados al ajuar, especialmente del conjunto de ítems de cestería y redes o mallas de fibra vegetal conservadas. Los estudios precedentes fueron complementados con información arqueológica y antropológica asociada a un conjunto de prácticas que creemos relevantes en vinculación con las particularidades del contexto tales como: tradiciones funerarias, tecnologías de producción cerámica y textil y modalidades de transporte de contenedores, entre las principales.","palabras_clave":"PRACTICAS FUNERARIAS|PUNA MERIDIONAL|TIERRAS BAJAS ORIENTALES|INTERACCIONES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190448,"idioma_id":5,"titulo":"Estrenos y reestrenos de las comedias de Pascual Guillén en los escenarios de Buenos Aires","resumen":"Este capítulo revisa cuáles fueron las obras de Pascual Guillén que se reestrenaron en Buenos Aires hasta 1936, pero se centra en las producciones originales que presentó una vez establecido en dicha ciudad a partir de 1939. Las reseñas y comentarios en la prensa de la época permiten deducir que, aunque durante esta segunda época de su producción teatral Pascual Guillén prácticamente no se apartó del tono ni de las convenciones propias de la comedia popular, cómica, flamenca, andaluza que había desarrollado en España, contó con la posibilidad de estrechar contacto con otros artistas exiliados, como Gori Muñoz o Salvador Valverde. El contacto con otros españoles y el intercambio con artistas argentinos le permitieron concebir nuevos argumentos y aliviar el exceso de elementos musicales flamencos que habían sido parte fundamental del despliegue escénico en las representaciones de aquella primera época madrileña junto a Quintero. Por esos años cuarenta, Buenos Aires era una especie de caldo de cultivo de los géneros cómicos. Operetas cómicas, disparates, farsas, revistas, sainetes y juguetes cómicos, entre otras formas, se sucedían en las diferentes carteleras, la mayoría de ellas nutridas por compañías y autores españoles, tales como Jacinto Benavente, Isaac Pacheco y Carlos Arniches, entre otros. Pascual Guillén, sin lugar a dudas, participó de ese momento teatral estelar que tuvo como notas características la combinación de teatro y música, cantaores, bailarines y demás, el despliegue de elementos espectaculares y la búsqueda de un público masivo que les reportara bonanza comercial tanto a autores como productores y empresarios teatrales. En esa especie de prolongación allende el mar del teatro cómico y popular madrileño de los años veinte y treinta, Pascual Guillén halló un lugar propio.","palabras_clave":"PASCUAL GUILLÉN|TEATRO REPUBLICANO|EXILIO EN BUENOS AIRES|COMEDIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190449,"idioma_id":5,"titulo":"Teatro y espectáculo en la obra dramática de Eduardo Borrás estrenada en Buenos Aires","resumen":"El capítulo analiza la presencia de Eduardo Borrás, dramaturgo español exiliado en Argentina, en el teatro rioplatense de los años cuarenta y cincuenta. Borrás constituye uno de los casos de asimilación profunda de escritores españoles exiliados en el mencionado país sudamericano, a punto tal que su procedencia española se disimuló notablemente luego de codearse con buena parte de la comunidad artística nacional más emblemática de los años cincuenta. Esta adaptación al nuevo medio se confirma con su aparición en varios de los más importantes diccionarios teatrales del Río de la Plata. En esas biografías las alusiones a las razones de su exilio o a sus vinculaciones políticas son breves y poco detalladas en contraste con sus contribuciones en el mundo artístico durante su estadía en el país de recepción. Tanto el cine como el teatro fueron para Eduardo Borrás sus hábitats naturales, pero fue el primero el que le dio al autor la posibilidad de trascender los límites nacionales, puesto que varios de sus guiones se filmaron en el extranjero, especialmente en México. A diferencia de otros exiliados que mantuvieron más activas sus redes de integración con la comunidad republicana en el exilio y que frecuentaron con mayor asiduidad en sus obras los conflictos políticos en España o el tema propio del exilio, Borrás pareció inclinarse hacia un cine y un teatro de corte más comercial liderado por un grupo de artistas locales que contaban con gran popularidad en el país e incluso con marcada proyección internacional, tales como Hugo del Carril, Narciso Ibáñez Menta, Amelia Bence, Tita Merello, Alberto Closas, entre otros. Por estas circunstancias, sus guiones y sus puestas en escena se embebieron de elementos del mundo cinematográfico ?decorados, efectos de luces y sonido, vestuario, etc.?, cuya espectacularidad le granjeó tanto simpatías como objeciones entre los críticos.","palabras_clave":"TEATRO|EXILIO REPUBLICANO|RECEPCIÓN|EDUARDO BORRAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190450,"idioma_id":5,"titulo":"Hitos del exilio teatral republicano en Argentina: El adefesio, La dama del alba y La casa de Bernarda Alba, tres estrenos mundiales en el Teatro Avenida","resumen":"Entre junio de 1944 y marzo de 1945 se produjeron en el Teatro Avenida tres estrenos mundiales que provocaron gran expectativa en el ámbito cultural porteño y cosecharon amplias y diversas repercusiones: El adefesio, de Rafael Alberti, ocurrido el 8 de junio de 1944; La dama del alba, de Alejandro Casona, el 3 de noviembre de ese mismo año; y La casa de Bernarda Alba, de Federico García Lorca, el 8 de marzo de 1945. Además del consabido reconocimiento con que contaban sus autores, ya entonces distinguidos representantes de la literatura española contemporánea, fue la presencia de la actriz catalana Margarita Xirgu (Barcelona, 1888-Montevideo, 1969) en la piel de los personajes protagónicos el motivo principal por el que esos estrenos fueron intensamente aclamados. Con todos ellos cultivó la actriz una intensa amistad, a tal punto que tanto Gorgo, la protagonista de El adefesio, como la Peregrina de Casona fueron compuestas por sus autores pensando en que ella las llevara a escena. La mayoría de los periódicos y revistas culturales porteños de larga tirada de la época anunciaron estos estrenos y los comentaron durante los días posteriores en sus secciones dedicadas a espectáculos. Desde los más conservadores, como La Nación o La Prensa, incluyendo la prensa católica de El Pueblo o Criterio, hasta los más antifascistas, como Antinazi, pasando por La Vanguardia, de tendencia socialista u otros, como Noticias Gráficas o El Diario. También algunos de menor tirada, tanto argentinos como españoles, en el caso de España Republicana y varios más. Sin distinción de perfil editorial e ideológico, estos estrenos convocaron la pluma de numerosos cronistas que no quisieron perder la oportunidad de dar cuenta de lo que entendían como acontecimientos culturales de gran magnitud. En ocasiones la prensa consiguió entrevistar a la actriz protagonista y directora de las obras, una de las principales encargadas de la divulgación de los estrenos; al tiempo que recogieron la palabra de Rafael Alberti y Alejandro Casona, presentes en las vísperas de sus respectivas presentaciones y también en el estreno mundial de la obra de García Lorca. Asimismo, revistas de crítica literaria y cultural con diversas procedencias editoriales, tales como Sur, Latitud, Correo Literario, entre otras, reservaron varias páginas para el análisis de estos estrenos. Estas crónicas y otros documentos visuales disponibles, tales como carteles, anuncios publicitarios, programas y fotografías, constituyen un material valioso para revisar la resonancia que tuvieron estos estrenos en el país sudamericano, los cuales en la actualidad perviven como momentos estelares de la obra republicana exiliada en Argentina.","palabras_clave":"RAFAEL ALBERTI|EXILIO ESPAÑOL|TEATRO |TEATRO AVENIDA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190451,"idioma_id":5,"titulo":"Tras los pasos de Francisco Madrid y su teatro exiliado en Argentina","resumen":"El propósito de este artículo es presentar algunos resultados de la investigación en curso sobre la vida y la obra de Francisco Madrid (1900-1952), exiliado en Argentina desde 1936. Periodista, crítico teatral y cinematográfico, dramaturgo, guionista y traductor, el estudio de su legado invita a explorar las mallas finas del exilio español republicano en Argentina. En particular, me detendré en su obra dramática, en lo que concierne tanto a su producción original, como también a sus trabajos de adaptación de obras extranjeras de renombre. Este acercamiento permite valorar la inserción de Francisco Madrid en el ámbito teatral y cultural argentino de los años cuarenta, una época de gran efervescencia para la escena rioplatense, puesto que la ciudad de Buenos Aires ya se había constituido en una de las capitales internacionales de la industria del teatro, atractiva para las grandes compañías extranjeras, y al mismo tiempo, gestora de nuevas inquietudes expresivas e ideológicas que cuajaron, por ejemplo, en el teatro independiente.","palabras_clave":"EXILIO REPUBLICANO|TEATRO|RECEPCION|RIO DE LA PLATA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190452,"idioma_id":5,"titulo":"Jacinto Grau en la escena teatral de Buenos Aires: los estrenos de El cuento de Barba Azul y La casa del diablo","resumen":"Jacinto Grau nació en 1877 en Barcelona y llegó a Argentina en junio de 1939, cuando habían transcurrido apenas dos meses desde el fin de la Guerra Civil Española. Luego de una estadía en Chile, decidió cruzar la cordillera y establecerse en la capital del país en busca de una mejor inserción en el mundo cultural y teatral. Entre otras actividades profesionales, consiguió estrenar en Buenos Aires dos de sus obras: El cuento de Barba Azul, en 1939, y La casa del diablo, en 1942. En esa ciudad argentina permaneció hasta su muerte, ocurrida el 14 de agosto de 1958. A través de la recuperación de los anuncios y las reseñas críticas de sus estrenos teatrales ha sido posible analizar algunos aspectos pertinentes de la recepción de dichos estrenos, como así también reconocer el nivel y la calidad de la adaptación del escritor español al ámbito teatral y cultural de Buenos Aires.","palabras_clave":"EXILIO REPUBLICANO|TEATRO|RECEPCIÓN|RÍO DE LA PLATA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190453,"idioma_id":5,"titulo":"La narrativa testimonial sobre los campos de concentración franceses: intervenciones en el exilio republicano","resumen":"Los testimonios sobre el internamiento en los campos de concentración del sur de Francia escritos por republicanos y republicanas españoles que emprendieron el éxodo en las postrimerías de la Guerra Civil Española conforman en la actualidad un objeto de estudio relevante dentro de la producción cultural del exilio, no solo por el amplio espectro temporal en que han circulado -comenzaron a publicarse en los años cuarenta en simultáneo con el funcionamiento de los campos y continúan apareciendo al día de hoy manuscritos editados por hijos o nietos de algunos supervivientes-, sino también por el interés creciente que vienen suscitando en el seno de la comunidad académica. En este ensayo me interesa acotar las características específicas del corpus testimonial sobre la experiencia concentracionaria en Francia a fin de reflexionar sobre cómo estos discursos han colaborado en la representación del campo y del exilio republicano. Asimismo, propongo revisar sucintamente algunos hitos significativos de la organización diacrónica o periodización de dichos testimonios, con especial interés en los contextos de circulación del exilio, para valorar en qué medida los exiliados republicanos, al tiempo que pensaron en su pasado reciente, colaboraron en los procesos históricos que tenían lugar más allá de España.","palabras_clave":"EXILIO REPUBLICANO|CAMPOS DE CONCENTRACIÓN |TESTIMONIO|ESPAÑA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190470,"idioma_id":4,"titulo":"Taphonomy of surface bone assemblages in coastal Patagonia: a case study","resumen":"Surface archaeological bone assemblages are a key source of information for understanding the regional properties of the zooarchaeological record in Patagonian coastal landscapes. The number of archaeological deposits that are exposed every year as a consequence of erosion is noticeable, and by applying different research tools, they may help improve our knowledge of the formation processes of these assemblages. In this paper we analyze archaeological site P 37 in order to understand bone modification patterns displayed in three bone samples exposed on surface and recovered successively in 2008, 2010 and 2011. P 37 is located in Southern Patagonia, Argentina, close to the high tide line of Santa Cruz estuary. Bones (mainly pinnipeds) and stone artifacts were lying on a sandy substrate along with few mollusk shells. Weathering profiles, bone fragment size and bone modification data have been considered to discuss the taphonomic history of the bone materials recovered. Results show that P 37 displays signs of past stability and is currently in a transitional situation towards a completely eroded condition. Weathering profiles are a relatively more sensitive line of evidence to differentiate surface and stratigraphic samples recovered at different time intervals. The general picture of P 37 is in agreement with that of a time exposure longer than the 16\/20 month observations that we have registered in this study. Nevertheless we could identify some taphonomic properties which could be informative of the transition between burial and exposure conditions in shorter time intervals than those displayed by the general weathering picture of the assemblage.","palabras_clave":"taphonomy|surface assemblages|Patagonia|Neotropics"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190471,"idioma_id":4,"titulo":"Osteometrics of South-Central Andean wild camelids: new standars","resumen":"The osteometry of Neotropical camelids has drawn increasing attention over the last years given its potential to segregate species. Here we present two new osteometric standards for appendicular bones of wild camelids from the South-Central Andes (>3500 m.a.s.l.): a vicuña (Vicugna vicugna) and a guanaco (Lama guanicoe). The vicuña is from Antofagasta de la Sierra, near the margins of its present southern range. The Andean guanaco is from Sierra del Aconquija, also in NW Argentina, where this species is poorly documented. These new standards are generally consistent with other available ones. While vicuñas and guanacos do not generally overlap in size, they do with their domestic counterparts: alpacas and llamas, respectively. The new measured guanaco individual is among the smallest known ones, and compares to other specimens from NW Argentina. The measured vicuña and guanaco front first phalanx, one of the most diagnostic elements, varies mainly in the breadth dimension of the articular surface and not so much in its width. The forelimb first phalanges of both camelids are about the same length, as are the rear ones and the second phalanges, unlike other studies have reported. Yet, the guanaco first phalanges are much more robust in their diaphysis. Thus, bone gracility, and not just gross maximum linear size, may be a distinctive trait in some cases. Some measures are more powerful than others to discriminate taxonomy, as has often been emphasized, although this should be used with caution until size and shape variation is further recognized. Variation recognition in wild camelid osteometry is crucial to help understand its whole range and to link it to specific conditions.","palabras_clave":"Osteometria|Camelidos|Andes Meridionales|Neotrópicos"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":190815,"idioma_id":5,"titulo":"El arte de pedir. Una introducción antropológica a prácticas suplicantes.","resumen":"Este libro da cuenta de la labor desarrollada durante el período 2012-2013 por el equipo de Investigacióndel proyecto denominado 'Ritos orales y desarrollo en dos pueblos indígenas de América Latina: un estudio comparativo de regímenes concomitantes de pobreza y propiedad.' Al mismo se han sumado importantes contribuciones de otros investigadores. Nuestra investigación parte de descripciones lingüísticas y etnográficas de numerosos contextos indoamericanos en donde las invocaciones a'dueños' de la tierra, el bosque, los cielos, las especies animales y vegetales son consideradas fundamentales para lograr prosperidad. Las mismas se utilizan regularmente para revertir ciclos de hambruna, miseria y carencia dealimentos, lluvias y salud. Por medio de ofrendas y plegarias denominadas 'rogaciones' o 'rogativas' se solicitan salud, riqueza, bienestar, buenas cosechas, buena caza y buena pesca. Aunque dichas categorías eran permanente y relacionalmente constituidas y descriptas desde perspectivas seculares y religiosas como fenómenos sociales, afectivos y políticos, carecíamos de descripciones etnográficas, y comparaciones precisas de las mecánicas propias de estos procesos de demanda. Si bien teníamos numerosas descripciones de ritos, plegarias e invocaciones a 'guardianes', 'amos' o 'dueños' de la tierra, el bosque, las aguas y distintas especies vegetales y animales, dichos espíritus administradores, protectores y propietarios de especies animales y vegetales, territorios y otras entidades (Seeger 1981: 181) y de cómo extendían un vínculo metafórico de paternidad y maternidad a numerosos contextos (Viveiros de Castro 2002: 82; Fausto 2008) de la vida cotidiana, hasta la conformación de este grupo de investigación no existía un estudio comparativo y sistemático de dichas oraciones, de sus contextos rituales, y mucho menos, de las modulaciones que los mismos ritos orales producen de las categorías 'pobreza' y 'propiedad', en las condicionespolíticas y sociales actuales.","palabras_clave":"Súplica|Pobreza|Oración|Economía"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":191132,"idioma_id":5,"titulo":"La república popular-liberal de Juan Espinosa: crónica de un fracaso ejemplar","resumen":"El Diccionario para el pueblo por un soldado&nbsp; de Juan Espinosa&nbsp; publicado en Lima en 1855 representa un texto fundamental para reconstruir en Latinoamérica las tensiones que atraviesan el cruce de la tradición republicana, la democracia y la defensa de los derechos individuales y colectivos. A fin de dimensionar la propuesta de Espinosa enmarco su análisis en la noción de 'Estado democrático' de Claude Lefort, ya que la interrogación que este dirige a la revolución política moderna no pone el eje en una forma de institucionalidad particular, sino en el modo de inscripción política de los conflictos sociales. En resumen, en el presente capítulo busco mostrar cómo la revolución democrática que se inicia en el siglo XVIII en América no es objeto de invención, sino de análisis. Este matiz que tomo de Lefort implica que la lectura ideológica que de ella se hizo, en este caso por Espinosa al acotar los sujetos de derechos, no ofusca las derivaciones prácticas que ya eran operativas aunque de forma difusa y no consciente de su alcance real (aun para la lectura de la historia de América que emprende el propio Lefort). Por tanto, tras la invención democrática el derecho no puede ya subordinarse a una lógica de conservación de un sistema de dominación, en tanto supone un valor simbólico de impugnación a toda práctica jurídica. Las diatribas de Espinosa contra el abatimiento moral de los americanos no le ocultan que su república política, democrática y popular radica, amén de su 'fracaso', en que lo socialmente legítimo se impone a la objetivación del derecho cada vez que este sea usurpado o que la ley deje de responder al 'carácter del pueblo'. ","palabras_clave":"REPUBLICANISMO|POPULISMO|LIBERALISMO|JUAN ESPINOSA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":191160,"idioma_id":4,"titulo":"Poéticas sonoras tradicionales. Modos de apropiación y percepción de músicas y prácticas ?andinas? en Buenos Aires","resumen":"Este trabajo focaliza en reflexiones teórico-metodológicas de abordaje comparativo de grupos de música tradicional integrados por migrantes y argentinos, denominados ?bandas de sikuris o sikus?, que constituyen el mapa de la identidad ?andina? de Bolivia y Perú en la Ciudad de Buenos Aires. Para ello, problematiza la multidimensionalidad de los procesos de producción musical a partir de dos aspectos centrales. Primero, aborda cómo este tipo de prácticas reproducen, crean y actualizan en el discurso y el ritual, sentidos, emociones y experiencias corporales vinculados al 'comunitarismo' y la ?complementariedad? en tanto unidad-visión del mundo andina. Segundo, cómo los sujetos perciben y resuelven las estructuras musicales microconflictivas surgidas en la experiencia de la performance -en particular en la ronda como ?ícono? de esta música- que apelan a significaciones sobre sonoridades tradicionales. El objetivo es analizar cómo en la práctica del ?saber hacer? música ?colectiva? ?entendida como una experiencia de ?liberación? y ?bienestar?-, se generan estrechos lazos emocionales vinculados con valores y creencias compartidos y un estado de percepción activa con ?el otro? y la ronda. A su vez, el trabajo devela cómo esta ?interconexión? alcanzada entre los tocadores produce inscripciones corporales que son vivenciadas de distinto modo según las trayectorias artístico-culturales y sociales de los mismos y que delimitan las agrupaciones.","palabras_clave":"MUSICA TRADICIONAL|CUERPO|EMOCIÓN|CREATIVIDAD"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":191333,"idioma_id":5,"titulo":"Reflexiones para repensar una teoría de la hegemonía","resumen":"Existen tres importantes limitaciones, en las teorizaciones sobre la hegemonía deGramsci y Laclau, que requieren de un trabajo de reelaboración. En primerlugar, en sus obras no hay una sistematización teórica clara, lo cual setraduce en un déficit a la hora de contar con una herramienta que guíe elanálisis de las situaciones concretas. En segundo lugar, si bien ambos autoresle otorgan una gran centralidad al lenguaje y a lo discursivo(respectivamente), no presentan un diálogo constructivo con las tradicioneslingüísticas o de análisis del discurso, de modo de retomar sus aportes y poderproponer líneas y metodologías de análisis claras. A mi entender, laprofundización de las miradas disciplinares y los encapsulamientos endeterminadas ortodoxias teóricas se han convertido en serios obstáculos paraavanzar en la elaboración de una mejor teoría de la hegemonía. Y en tercerlugar, las teorizaciones de Gramsci y de Laclau fueron elaboradas para procesarsituaciones de derrota y esto habría sesgado sus conceptualizaciones, por loque no serían apropiadas, tal como fueron formuladas originalmente, paraanalizar coyunturas y estrategias de avance en la disputa política como, porejemplo, la realidad latinoamericana de la primera década del siglo XXI. En lamisma es posible observar una importante capacidad\/habilidad de las fuerzas decentro-izquierda e izquierda para disputar, durante períodos relativamenteextensos, la hegemonía en el terreno de la lucha electoral y para emplear elEstado en pos de intentar superar las realidades que había construido elneoliberalismo en todos los países de la región.En relación a estas tres limitaciones, en elpresente trabajo procuro (1) señalar los contextos en los que se elaboraron lasteorizaciónes sobre la hegemonía, a fin de destacar la necesidad de sureconceptualización para dar cuenta de la realidad latinoamericanacontemporánea, (2) justificar la pertinencia de un enfoque interdisciplinario ymultiteórico para la elaboración de una teoría de la hegemonía, y (3) reseñarmuy brevemente los principales aportes que quiero retomar de las elaboracionesde Marx, Gramsci, Laclau, Voloshinov\/Bajtín y algunos analistas del discurso(Fairclough, van Dijk y Angenot).","palabras_clave":"Hegemonía|Análisis del Discurso|Gramsci|Laclau"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":191335,"idioma_id":5,"titulo":"Reconceptualización de las formas sociales de producción que se enfrentan en la región pampeana","resumen":"En este capítulo, una primera parte esta dedicada a distinguir los distintos recursos productivos que sirven para, analizando sus combinaciones, diferenciar entre las formas sociales de producción. En una segunda parte, estudiando estas combinaciones históricamente, conceptualizaremos las distintas formas sociales de producción que se fueron sucediendo en la historia del agro pampeano. Y, en la última parte, abordamos las tensiones que se generan, entre estas distintas formas sociales de producción en la región pampeana, en torno a estos recursos.","palabras_clave":"Concentración|Formas de producción|Agricultura|Argentina"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":191336,"idioma_id":5,"titulo":"Subjetividades subordinadas en la agricultura pampeana: procesos de concentración, recursos productivos y sujetos agrarios","resumen":"En las últimas décadas ha tenido lugar un intenso proceso de concentración de la producción agrícola en la región pampeana, que fue acompañado por sustanciales modificaciones en las formas sociales en que se organizaba esta actividad. Existieron una serie de factores que influyeron para que estos cambios acontecieran, pero los mismos no hubieran sido posibles si los actores poseedores de los distintos recursos productivos no hubieran adoptado conductas que concretaran estas transformaciones. Es que los diferentes modelos de desarrollo agrario precisan de subjetividades que los encarnen. En el presente capítulo reflexionaremos acerca de estas modificaciones en los sujetos agrarios a fin de aportar al conocimiento de cómo se construyeron subjetividades subordinadas a la lógica del capital concentrador que hicieron posible la concretización de una fuerte tendencia en favor del despliegue de grandes y enormes unidades productivas capitalistas en la agricultura pampeana.","palabras_clave":"Subjetividad|Agricultura|Argentina|Megaempresas"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":191337,"idioma_id":5,"titulo":"10) La ideología de los productores rurales bonaerenses en   la actualidad","resumen":"A la par de las transformaciones ocurridas en las últimas décadas en el agro pampeano se gestó una discursividad que se construyecomo hegemónica en el discurso público sobre la cuestión agraria. Enotros trabajos (Balsa, 2007; Liaudat, 2013 y 2015) hemos indagado ensus características y mostrado cómo una particular combinación entre ideas tecnologizantes propias del discurso de los agronegocios yalgunos núcleos conceptuales propios de la discursividad liberal-conservadora aparecen regularmente en los discursos públicos de las entidades técnicas, gremiales, empresariales, del Estado y de los mediosde comunicación.","palabras_clave":"Ideología|Hegemonía|Agricultura|Encuesta"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":191351,"idioma_id":5,"titulo":"Algunos problemas de epistemología social: probabilidades grupales dinámicas","resumen":"The article aims to discuss and model a satisfactory concept of group probability; this task can be seen as a particular aspect of the more general question of how to aggregate intentional individual attitudes into a single collective attitude. For the most part my proposal will leave the exact aggregation mechanism for probabilities open. Rather, I aim at solving a previous aspect of the aggregation problem, to wit, I seek to clarify which individual probability functions are to be taken into account at the time of determining the probabilities of the group as a whole. I argue that the probabilities that ought to be aggregated are the individual functions conditionalized on group knowledge. But, as it happens, there are at least two well-defined ways in which we can attribute propositional knowledge to a group: common knowledge, and distributed knowledge. This leads to two different ways in which we can conditionalize. I contend that we should actually focus on the distance between the two; this leads to a dynamic concept of group probability. To address this problem I begin by presenting some standard tools from epistemic logic that enable us to characterize both common and distributed knowledge. I then explain how the machinery of public announcement logics can bridge the gap between the two. Next I present my perspective on dynamic group probabilities in a Kripke framework enriched with probabilities; we will see how to use public announcement logics also in the probabilistic setting. The proposal is further refined by considering a geometric pooling method on the conditional measures, which enables us to establish some connections with technical results from the recent literature.","palabras_clave":"Probability aggregation|common knowledge|distributed knowledge|public announcements logic"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":191385,"idioma_id":5,"titulo":"Jorge Romero Brest","resumen":"Análisis de la labor como crítico e historiador del arte de Jorge Romero Brest, presentación de sus datos biográficos, selección bibliográfica y presentación de uno de sus textos más significativos en su trayectoria profesional: el prólogo al libro Pintores y grabadores rioplatenses, de 1951.","palabras_clave":"ROMERO BREST|CRITICA|MODERNISMO|PUBLICACIONES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":191454,"idioma_id":5,"titulo":"Reciclar material y trabajar como cooperado. La producción de prácticas colectivas en una cooperativa de reciclaje","resumen":"Este artículo es una reformulación de la ponencia presentada en la XRAM,el cual se propone repensar, a partir del abordaje etnográfico de una cooperativa de reciclaje de San Pablo, la asimilación inequívoca de valores morales y prácticas colectivas. Se analiza qué importancia adquieren dichos valores en la práctica y cómo una cierta imagen ideal de lo que sería una cooperativa y el 'ser trabajador' es negociada y resignificada en los discursos y prácticas cotidianas.  El objetivo de este artículo es mostrar, a partir de una experiencia corta de trabajo de campo, que la producción de prácticas colectivas es un juego dinámico y negociado.","palabras_clave":"POLITICA|ANTROPOLOGÍA|RECICLAJE|COOPERATIVA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":191470,"idioma_id":4,"titulo":"'Malaise in political representation: Citizen attitudes and sociocultural tensions in Argentine democracy'","resumen":"To what extent does politics represent the interests and opinions of the social groups under its sway? What factors play a role in determining preferences for and levels of satisfaction with democratic politics? Argentina is an interesting case of analysis. Between 1930 and 1983, it alternated between civil and military governments. Its recent history is plagued with extreme experiences included the claim of 'all go home' to politicians experienced in 2001. Based on an original survey, we analyse the three dimensions of malaise in representation: disaffection, disapproval, and distrust. We examine the relationship between this phenomenon and a set of social, cultural, and political factors that influence its structure; before, finally, looking at the relationship between malaise and the democratic regime.","palabras_clave":"DEMOCRACIA|REPRESENTACIÓN|MALESTAR|AMÉRICA LATINA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":192171,"idioma_id":5,"titulo":"Descifrar mundos estatales. Sobre la circulación de autoridad en las burocracias públicas","resumen":"La idea de que el Estado argentino carece de una burocracia de carrera, organizada en función de criterios de reclutamiento y promoción meritocráticos y formales, es un punto bien establecido en la literatura especializada. Sin embargo, esta aceptación contrasta con la ausencia de estudios que, frente a ello, busquen comprender las dinámicas relacionales que subyacen en la circulación de funcionarios en las organizaciones estatales. En parte, se podría pensar que esto es así debido a los límites que ciertas categorías políticas implican, por su formalismo o por su carácter normativo, para descifrar mundos estatales atípicos. A partir del relato de dos experiencias de ascenso y descenso de funcionarios públicos, este texto se propone: en primer lugar, explicitar las alternativas conceptuales y metodológicas que orientaron la interpretación de dichas dinámicas y mostrar el uso que, en este caso, se hizo de ciertas categorías sociológicas para comprenderlas; en segundo lugar, realizar una reflexión metodológica de orden más general sobre la posible fecundidad de utilizar las sociologías interpretativas en la interpretación del funcionamiento de organizaciones políticas.","palabras_clave":"FUNCIONARIOS|DESIGNACIONES|CIRCULACIÓN|BUROCRACIA ASISTENCIAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":192604,"idioma_id":5,"titulo":"UNIDAD TEMÁTICA NÚMERO 1. HISTORIA","resumen":".","palabras_clave":"CURSO DE ADMISIÓN 2015|EDUCACIÓN FÍSICA|EDUCACIÓN SUPERIOR"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":192802,"idioma_id":4,"titulo":"Tiempo de retorno del estado: Realidades y desafíos del seguimiento y la evaluación de políticas y programas en la Argentina.","resumen":"capítulo Tiempo de retorno del estado: Realidades y desafíos del seguimiento y la evaluación de políticas y programas en la Argentina. Neirotti N., Brissón ME, Mattalini M. en el libro: El Panorama de los Sistemas Nacionales de Seguimiento y Evaluación de Programas y Políticas Públicas en América Latina.","palabras_clave":"Evaluación|Estructuras y dispositivos|Políticas Públicas"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":192836,"idioma_id":5,"titulo":"Lo que la realización no es","resumen":"En este trabajo, brindo razones para pensar que el enfoque dimensionado de la realización en neurociencia está profundamente desencaminado, de varias maneras, en la comprensión de la realización física. En primer lugar, el enfoque dimensionado ofrece una lectura tendenciosa y poco caritativa de las divergencias teóricas entre las propuestas clásicas de Putnam (1967) y Block y Fodor (1972). En segundo lugar, la realización dimensionada no posee los recursos conceptuales necesarios para formular adecuadamente la tesis de la realizabilidad múltiple de lo mental, pues implica la existencia de casos espurios de realización múltiple.","palabras_clave":"Fisicalismo|Realizabilidad Múltiple|Mecanismo|Neurociencia"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":192892,"idioma_id":5,"titulo":"Los cuerpos invisibles. Sobre las aguafuertes cariocas de Roberto Arlt","resumen":"En este capítulo se pretende continuar con la línea metodológica en el estudio sobre la obra del escritor periodista que inauguró Saítta y que continuó Juárez, para observar cómo la imagen de autor que la crítica ha establecido a propósito de la figura de Roberto Arlt, se tensiona y establece nuevas asociaciones ideológicas y literarias en el corpus de las crónicas cariocas. Si bien el viaje que el aguafuertista realizó durante un año por España y África puede ser considerado como el más importante de su carrera,  los recorridos que llevó a cabo dentro del país y por algunos territorios de Latinoamérica también presentan elementos que resultan productivos a la hora de reflexionar sobre la producción periodística de Arlt. Es por eso, que el objetivo de este trabajo consiste en analizar la ?prosa de prensa? que el escritor configura en sus aguafuertes sobre Río de Janeiro, para observar qué afiliaciones ideológicas, estéticas y literarias confluyen en el espacio de la crónica. Se intentará demostrar cómo en el corpus de notas cariocas emerge un entramado de ideas, modos de ver y de considerar ?lo otro? que no coincide con las figuraciones de Arlt en tanto escritor ?marginal?, para acercarlo, en cambio, al pensamiento positivista argentino. Para ello, se estudiará, en primer lugar, qué imágenes sobre lo negro figuran en los artículos que componen el corpus brasileño y cuál es la biblioteca a la que el cronista refiere en dichas descripciones. Si bien Arlt afirma no estar interesado en representar las particularidades de estos ?cuerpos invisibles?, en muchas de sus notas refiere a partir de clichés, mayormente estigmatizantes, la cultura negra presente en Brasil. En segundo lugar, se intentará mostrar el vínculo que existe entre la mirada que Arlt presenta en estas aguafuertes y las descripciones sobre la cultura africana que figuran en el texto de José Ingenieros titulado ?San Vicente. Los negros?. Por último, y con el objetivo de repensar la figura de Arlt como cronista de denuncia, se observará cómo las representaciones fosilizadas sobre lo negro conviven conflictivamente con la presencia de un discurso antiesclavista en el corpus carioca.","palabras_clave":"PRENSA|CRONICAS|VIAJE|ARLT"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":192961,"idioma_id":5,"titulo":"El reconocimiento del otro y de sí mismo en América Latina.","resumen":"Para Arturo A. Roig la autoidentificación es ejercida por un sujeto social e histórico. Su  categoría a priori antropológico alude a un ?ponerse? a sí mismo, ese sujeto plural, como tema de reflexión, reconociéndose como valioso desde la propia cotidianidad e historicidad, en que se gesta a sí mismo. En el marco de lo que Martí llamara Nuestra América conocernos a nosotros mismos constituye un saber de liberación. Este a priori cobra dimensión ético- política, como punto de partida de la afirmación de la dignidad plena de todo ser humano. Pero, además, al ser el ser humano parte del orden inmanente a la naturaleza, éste incumbe intrínsecamente a su condición humana, y su cuidado es incluido en su responsabilidad por el reconocimiento de la propia dignidad. Una filosofía intercultural es así  entendida como conjunto de voces dentro de un universo discursivo en que se detectan presencias y ausencias, e implica la problematización de dimensiones intra e inter culturales, basada en el reconocimiento de posibilidades de comprensión del otro, constituyéndose en una forma de pensamiento alternativo, abordando las profundas asimetrías que tienden a naturalizar la exclusión de los sujetos sociales más desposeídos, entre ellos los pueblos indígenas y afrodescendientes.","palabras_clave":"NUESTRA AMERICA|RECONOCIMIENTO|PUEBLOS INDIGENAS|AFRODESCENDIENTES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":193364,"idioma_id":5,"titulo":"Nota de los compiladores","resumen":"Nota introductoria al 3er volumen de la serie Clic!, Fotografía y Percepción. El mismo recorre distintas reflexiones sobre la recepción y la mirada, la producción de sentido en torno de la imagen fotográfica y, también, sus restos de insignificancia. Resuenan en estos textos los debates e influencias teóricas que han atravesado la conformación y el devenir de los estudios semióticos\/semiológicos y de análisis del discurso. Desde los aportes más tempranos de Roland Barthes que se inscribían en el intento de extender el modelo de análisis saussuriano de la lengua al estudio de la imagen y otros sistemas significantes a sus elaboraciones más tardías contenidas en La Cámara Lúcida, que destacaban el carácter indiciario de la fotografía 'lastrada por la contingencia' y la imposibilidad de refererise a ella en singular, como La Fotografía. Las ideas de Charles S. Peirce sobre el signo indicial y su modelo terciario han sido a su vez recuperados por Philippe Dubois en su teorización sobre el acto fotográfico. Mientras que las tensiones que se plantean entre indicialidad e iconicidad del signo fotográfico son abordadas por Jean-Marie Schaeffer, entre otros.Se reconoce en las discusiones teóricas un desplazamiento general del interés por el signo hacia el interés por el discurso, de las unidades a los conjuntos significantes; correlato también de la puesta en discusión del ahistoricismo estructuralista y la incorporación de conceptualizaciones sobre la producción discursiva como práctica material, históricamente situada. Este desplazamiento se evidencia en los análisis que abordan las fotografías como prácticas discursivas, insertas -en la línea señalada por Foucault- en procesos técnicos, instituciones, patrones de comportamiento, formas pedagógicas. Los interrogantes pasan de dar prioridad a la cuestión del referente a preguntarse por las condiciones de producción de la práctica discursiva en sí misma, sus formas de animar ciertos significados antes que des-cubrirlos. Como indica John Tagg, no se trata de la fotografía como 'prueba' de la historia, sino como elemento histórico. El último capítulo del volumen se aproxima a la mirada psicoanalítica sobre la producción significante y las posibilidades de la fotografía -originada en una voluntad de registro exacto de la realidad inmediata- de abrir el acceso a lo fantástico, lo onírico, lo imaginario, lo inconsciente. Se recrea en la imagen fotográfica, en su toma, en su contemplación, una vez más la tensión entre Eros y Tánatos. Si por un lado la foto congela, mortifica, domina, cosifica -y entonces algo de ella parece cifrarse irreductiblemente en el orden de la perversión-, por otro lado la solicitación del sentido, de la palabra, del reconocimiento, cobijan también la demanda del otro, la voluntad de encuentro que no deja -pese a todo- de habitar en el deseo.","palabras_clave":"FOTOGRAFIA|SOCIEDAD|ENSAYO SOCIOLOGICO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":193365,"idioma_id":5,"titulo":"Nota de los compiladores","resumen":"Nota introductoria al volumen Fotografía y Estética. El mismo compila textos que revisan los diálogos que se han establecido en la práctica fotográfica entre arte y técnica en sus posibilidades expresivas y creativas, en tanto ambos constituyen modalidades de producción de lo sensible. Como bien ha advertido Benjamin, la reproductibilidad técnica -y específicamente la fotografía- introduce una transformación cualitativa en el hacer artístico, en sus procedimientos de realización, sus sistemas de circulación y de consumo, sus condiciones de experiencia y percepción. El reconocimiento de la Fotografía como arte no ha estado exento de debates, y este volumen recorre algunos de los más sobresalientes. Por ejemplo, la confrontación entre 'puristas' y 'pictorialistas', o entre partidarios del documentalismo y de la experimentación estética; las tensiones entre la 'objetividad' y la cuestión del 'estilo' o las marcas de la enunciación del autor o autora de la fotografía. Varios de los textos indagan en las relaciones entre la fotografía y otras artes. Con la pintura (en cuyo ámbito -como nos recuerda Jorge Glusberg en este volumen- se había construido la demanda de exactitud mimética que condicionó buena parte de los desarrollos iniciales de la fotografía), contribuyendo a perfeccionar y transformar la representación pictórica, que ya nunca volvería a ser igual, y experimentando a su vez con el retoque manual sobre negativos y copias fotográficas, con la elaboración de fotomontajes y collages. En este sentido,la introducción de la imagen digital da cuenta de una intensificación de las intervenciones en la fase de postproducción, facilitada por los programas de edición de imágenes. Con el cine, la fotografía se constituye en campo de indagación, de exploración poética, y aquel en estímulo, inspiración y tema de la fotografía. Se destaca en los textos reunidos la reflexión sobre la materialidad de la fotografía como huella de señales luminosas y las posibilidades de exploración que permite en términos de la relación de la imagen con lo real, con el espacio y el tiempo, con el azar, con la potencia del instante, tal como ha sido pensado por Bachelard y también por Cartier-Bresson. Se indaga también en la fotografía como materialización de una mirada moderna, en su estrecha vinculación con la máquina, con la matriz científico-técnica y el ideal de proveer un medio para que la naturaleza pueda 'reproducirse a sí misma'. Al mismo tiempo, al modo de la dialéctica entre mito y logos que exploran Horkheimer y Adorno en su Dialéctica de la Ilustración, algunos trabajos se detienen en la presencia de lo mítico, de lo mágico, de lo sagrado,en fin del valor cultual -para volver, una vez más, a Benjamin- en los usos fetichistas e idólatras de la imagen fotográfica. Si la relación entre Fotografía y Modernidad no se pone en discusión, las transformaciones posmodernas en la producción de imágenes y en los modos de mirar habilitan en cambio debates productivos que lejos están de haber sido agotados. Alain Renaud advierte al respecto que la visibilidad ha mudado de régimen cualitativamente, cambiando tanto el modo de producción cuanto el de almacenamiento, de intercambio y de uso social de las imágenes, mientras que Armando Silva pone el acento en las formas de creación que permite la producción de imágenes numéricas, ya no tanto ancladas en el lugar, sino en caída de tiempo, como fragmento sin espacio fijo, como flujo.","palabras_clave":"FOTOGRAFIA|ESTETICA|ENSAYO SOCIOLOGICO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":193403,"idioma_id":5,"titulo":"Gentianaceae, Linderniaceae, Menyanthaceae, Orobanchaceae, Plantaginaceae, Primulaceae, Santalceae","resumen":"En el presente trabajo se realizó una nómina de las especies de las familias Gentianaceae (2 géneros y 2 especies), Linderniaceae (2 géneros y 2 especies), Orobanchaceae (3 géneros y 6 especies), Menyanthaceae (1 género y 1 especie), Plantaginaceae (10 géneros con 28 especies, 2 subespecies y 2 variedades), Primulaceae (4 géneros y 4 especies) y Santalaceae (2 géneros y 6 especies) que crecen en el Parque Nacional Mburucuyá, Mburucuyá, Corrientes; con actualización de los nombres de acuerdo al sistema del APG III; además se incorporaron datos del hábito de la planta, status y ambiente donde crece cada una de especies.","palabras_clave":"Taxonomía|Mburucuyá"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":193452,"idioma_id":5,"titulo":"Higuera, circunferencia y río: notas sobre el convencionalismo semántico a partir del Crátilo de Platón y Canino de Giórgos Lánthimos","resumen":"En este trabajo me propongo explorar la tesis según la cual los nombres de una lengua son instituidos de manera convencional, a causa del acuerdo o del empleo frecuente de los términos por parte de un individuo o de una comunidad. Basándome en el tratamiento que de esta tesis hacen Platón en el Crátilo y Giórgos Lánthimos en su película Kynódontas, me detendré especialmente en el análisis de la figura del instaurador de nombres, en vistas a considerar los fundamentos e implicancias de su acción. La hipótesis que intentaré defender es que mientras en el Crátilo la actividad del instaurador de nombres se presenta supeditada al conocimiento de las Formas y regulada por el uso de los términos que hace el dialéctico, en Kynódontas el instaurador de nombres procede de manera completamente arbitraria y su actividad redunda en el poder sobre la vida de quienes están sometidos a él, poder que se pone en entredicho cuando se cuelan en la comunidad algunos significados no regulados por el instaurador.","palabras_clave":"CRATILO|KYNODONTAS|LENGUAJE|CONVENCIONALISMO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":193536,"idioma_id":4,"titulo":"Gaining Insight into Plant Responses to Beneficial and Pathogenic Microorganisms Using Metabolomic and Transcriptomic Approaches","resumen":"Plants are constantly interacting with microorganisms. Many of them have the potential to cause disease, while many other may establish beneficial interactions where plants enhance their ability to incorporate important nutrients and improve disease resistance. During these interactions, plants must regulate the expression of thousands of genes, which ultimately triggers distinct hormonal signaling pathways and affects the concentration of numerous metabolites. Transcriptomics and metabolomics have played a pivotal role in identifying the genes and metabolites involved in such responses, which has given crucial hints to refine our current strategies for plant protection and crop yield improvement. However, there is still a gap on our knowledge on many features that distinguish the interplay between plants and microorganisms. This chapter initially discusses the contributions of these high-throughput technologies to the understanding of this field of research, and ends with future prospects in the search for interaction-specific biomarker genes and metabolites","palabras_clave":"PLANT DEFENCE|BENEFICIAL MICROORGANISMS|PATHOGENS|TRANSCRIPTOMICS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":193818,"idioma_id":5,"titulo":"La ruta de la Lingüística del Texto","resumen":"La metáfora madre que subyace a esta convocatoria, ?Rutas de la lingüística?, es de naturaleza espacial: la lingüística se concibe como un espacio por recorrer y las diferentes sub-disciplinas o enfoques serían rutas posibles, que las personas ? los lingüistas ? escogerían según sus intereses y metas de investigación. Me voy a permitir reformular  y expandir la metáfora convocante, para poder organizar y ordenar con más comodidad esta presentación.    Tal vez la idea de recorrido (y más aún el plural, recorridos) sea más adecuada para la presentación de las corrientes y sub-disciplinas lingüísticas que la de ruta, puesto que esta sugiere un punto de partida y de llegada, en un trazado preexistente y dado, y por tanto, cierto carácter estático: en cambio, los recorridos permiten alternativas (distintos caminos, desvíos e incluso el cruce y la bifurcación), y el ejercicio de la iniciativa y la variación en la elección de senderos y caminos posibles por parte de quien realiza el recorrido. A esta metáfora responde mejor la lingüística del texto (en adelante, LT), puesto que como dirección de investigación constituye más un conglomerado de enfoques, cuya unidad consiste en la concentración en el objeto de estudio, que, de hecho, da el nombre a la subdisciplina. La LT es un recorrido posible, flexible y variable en sí dentro de los muchos otros que la lingüística ofrece. Ordenaré esta exposición en dos partes de muy desigual extensión: en primer lugar, presentaré un panorama de la LT como campo de trabajo dentro de la disciplina,  incluyendo un recorrido histórico breve y la presentación sintética de los principales temas de trabajo y de las líneas actuales de investigación; en segundo lugar, expondré de manera muy condensada la introducción de la LT en el contexto de la lingüística argentina y el recorrido personal realizado , es decir, la adopción de la LT como una alternativa teórico-metodológica en el desarrollo de la labor de investigación.","palabras_clave":"Lingüística del Texto|Corrientes de la lingüistica|Análisis del discurso"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":194660,"idioma_id":5,"titulo":"Transporte, Metabolismo y Mecanismos de Acción de las Hormonas Tiroideas","resumen":"NO SE DISPONE","palabras_clave":"TIROIDES|BIOSÍNTESIS|MECANISMOS DE ACCIÓN|METABOLISMO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":194727,"idioma_id":4,"titulo":"Fermented beverages from the Andean region","resumen":"Latin American indigenous tribes used the fermentation processes as means of food processing and preservation. In the Andean regions of Latin America where the Inca empire had its civilization, the production of beverages was among the major practices that involved a natural fermentation processes. For the Inca?s population, the production of alcoholic beverages was important because they played an essential role in their spiritual beliefs., These drinks were considered to have a high symbolism because of the Incan cosmovision. The present chapter describes the traditional fermented beverages of pre-Columbian cultures of the Andean region of South America. Spontaneous fermentation processes were used as a way of alcohol production by using native (in pre-Colombian time) and Old World crops (in post-Colombian time). By allowing an aqueous mixture of fruits or vegetables to ferment, a great variety of alcoholic beverages with a low to a moderate alcoholic content (2?12%) were obtained. Such substrates are rich in fermentable sugars and\/or polysaccharides. In some cases preliminary steps such as chewing, germination or roasting were carried out to allow the process to easily occur and also to obtain assorted drinks. This chapter elaborates on the raw materials used, including: Manioc or Çassava, Banana, Sugar Cane, Sweet Potato, Rice, Cacao, Carob Beans, Maize and others. Maize production was of great importance, and for this reason, food crop also became an ingredient beverage manufacturing and this elaboration Method was spread along the entire Andean region. Thus the most important and well known drink in this region was a Maize beer or maize-based beverage, called chicha. In Andean Latin America all chicha-like beverages with similar production methodology were called chicha as well. Nowadays many of these beverages are still being artisanally produced and consumed although they may have undergone changes in their composition and chemical characteristics due to the incorporation of new raw materials and elaboration methodologies. The main objective of this chapter is to introduce an improved knowledge of these traditional Andean fermented beverages, highlighting those coming from the Northwest region of Argentina. A revision of the processes involved in their manufacture will be useful in understanding biochemical changes associated to the action of native microorganisms on raw materials.Traditional and new technological procedures involved in their manufacture are discussed. By increasing and updating the available knowledge from a technicaland scientific point of view it is expected to make a helpful contribution for those who are interested in traditional fermented foods.","palabras_clave":"Fermentation|traditional|beverages|andes"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":194753,"idioma_id":5,"titulo":"Phylum Nematoda","resumen":"VER ADJUNTO","palabras_clave":"MACROPARASITO|DIVERSIDAD|BIOLOGÍA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":194799,"idioma_id":5,"titulo":"La aplicación de fosfito en Kiwi como herramienta tecnológica para el agregado de valor.","resumen":"El trabajo está vinculado con la aplicación de fosfito (Phi) como herramienta tecnológica para el agregado de valor del kiwi (Actinidia deliciosa). El kiwi es climatérico y al no tener un cambio de color externo mientras madura, el contenido de sólidos solubles totales (SST) es el índice utilizado para la cosecha. El contenido de materia seca (%MS) está relacionado con la calidad sensorial y el potencial de almacenamiento. El Phi induce muchas respuestas asociadas a los mecanismos de defensa de las plantas y al metabolismo secundario y no es un producto contaminante del ambiente. Seis aplicaciones foliares semanales de 0,3% (v\/v) de KPhi (30% P2O5, 20% de K2O) o agua (control) se realizaron en una plantación de kiwi ´Hayward´. Se evaluó la respuesta del KPhi en los índices de madurez de la fruta a la cosecha y después de las 10 días a 20°C (vida de anaquel). También se evaluó la tolerancia a la podredumbre gris causada por Botrytis cinerea, para lo cual fruta tratada y no tratada se inoculó con el patógeno. La fruta tratada con Phi presentó a cosecha mayor %MS (control: 15,6%; KPhi: 17,4%), SST (Control: 5,8%; KPhi: 6,5%) respecto al control y también mostró mejor calidad en términos de SST y firmeza en la vida de anaquel. El kiwi tratado con KPhi resultó más tolerante a la podredumbre gris, con menor incidencia y severidad respecto al control. Estos resultados preliminares indican que el uso de fosfito puede inducir cambios metabólicos que contribuyen con la calidad y la tolerancia a pudriciones.","palabras_clave":"Innovación|transferencia|kiwi"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":194846,"idioma_id":4,"titulo":"FORTY YEARS OF PRIMATOLOGY IN ARGENTINA, THE VERY FIRST VOLUME","resumen":"For those outside of the primatological community, it may seem surprising that this is the first volume about the primatology in Argentina in almost 40 years. In Argentina we found 5 species of extant primates that inhabit different type of forests in the North part of the country especially in the Northeastern region with different conservation status. Alouatta caraya (black and gold howler monkeys), Alouatta guariba clamitans (brown howler monkeys), Aotus azarai (owl monkeys), Cebus nigritus -taxonomically synonymous with Sapajus nigritus- (black horned capuchins), and Cebus paraguayanus -taxonomically synonymous with Sapajus cay- (brown-capped capuchins)","palabras_clave":"Primatology|Argentina"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":194873,"idioma_id":5,"titulo":"Vegetales IV Gama: Producción, comercialización y aspectos sanitarios en la región NOA y en Argentina.","resumen":"Las frutas y hortalizas son consideradas, desde el punto de vista nutricional, como una excelente fuente de agua, minerales, fibras y compuestos bioactivos a los que se les atribuyen efectos benéficos para la salud humana. Sin embargo, en Argentina, el consumo de frutas y hortalizas alcanza valores muy inferiores de lo sugerido por la FAO y OMS, el cual corresponde a 400g de por persona. En los últimos años, a nivel mundial, ha crecido la demanda de frutas y hortalizas frescas y se ofrecen en el mercado internacional una amplia variedad de vegetales IV Gama o mínimamente procesados. Los aspectos críticos a considerar durante la comercialización de este tipo de alimentos son la corta vida útil y la necesidad de contar con una logística que asegure la cadena de frío hasta el lugar de venta y su almacenamiento refrigerado hasta el momento del consumo. En este capítulo se analizan las tendencias del mercado de vegetales de la IV Gama, las características de sus consumidores y los principales problemas asociados con su elaboración en la región NOA y en Argentina. Así mismo se evalúa la situación de la normativa sanitaria en nuestro país, los aspectos a mejorar en la producción y se plantean pautas para incrementar el consumo de frutas y hortalizas mínimamente procesadas.","palabras_clave":"VEGETALLES MINIMAMENTE PROCESADOS|PRODUCCIÓN|COMERCIALIZACIÓN"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":194923,"idioma_id":4,"titulo":"Computational prediction of novel miRNAs from genome-wide data.","resumen":"The computational prediction of novel microRNAs (miRNAs) within a full genome involves identifying sequences having the highest chance of being bona fide miRNA precursors (pre-miRNAs). These sequences are usually named candidates to miRNA. The well-known pre-miRNAs are usually only a few in comparison to the hundreds of thousands of potential candidates to miRNA that have to be analyzed. Although the selection of positive labeled examples is straightforward, it is very difficult to build a set of negative examples in order to obtain a good set of training samples for a supervised method. In this chapter we describe an approach to this problem, based on the unsupervised clustering of unlabeled sequences fromgenome-wide data, and the well-known miRNA precursors for the organism under study. Therefore, the protocol developed allows for quick identification of the best candidates to miRNA as those sequences clustered together with known precursors.","palabras_clave":"Genomics|MicroRNA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":194992,"idioma_id":5,"titulo":"Una aproximación al Envejecimiento Activo: el caso de la Ciudad de Buenos Aires","resumen":"El envejecimiento activo ha demostrado ser un paradigma integral y flexible que intenta dar respuesta al desafío que representa el incremento de las personas mayores a nivel global; en tanto que, envejecer activamente, supone propiciar el bienestar de las personas mayores. Según la definición oficial que propone la Organización Mundial de la Salud (2002), el envejecimiento activo es el proceso de optimización de las oportunidades para la salud, la participación y la seguridad, con el fin de mejorar la calidad de vida conforme las personas envejecen.En este trabajo nos proponemos presentar un panorama preliminar de la situación de los adultos mayores de la Ciudad de Buenos Aires respecto a las dimensiones que definen el envejecimiento activo: el empleo, la participación social, la salud percibida, el nivel educativo y el contexto familiar entre otros. Para ello utilizamos datos primarios resultantes del proyecto ?Seguridad Social, Políticas Sociales y Redes de Apoyo en la Vejez. Un análisis integral entre programas Institucionales y actores? (UBACyT 2014). Estos resultados nos permitieron un primer acercamiento al estudio del envejecimiento activo en la población urbana local. Este panorama brinda información valiosa sobre la temática y permite identificar, específicamente, los factores que favorecen el incremento de un envejecimiento saludable y activo. De este modo, los resultados que se presentan son útiles para el diseño y perfeccionamiento de políticas sociales dirigidas a mejorar la calidad de vida de las personas mayores. A su vez, estos hallazgos sirven para la triangulación con futuros estudios y contextualizan los datos cualitativos de nuestra investigación.","palabras_clave":"ENVEJECIMIENTO ACTIVO|DIMENSIONES|PERSONAS MAYORES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195036,"idioma_id":5,"titulo":"VIOLENCIA DE GÉNERO Y DICTADURA CÍVICO-MILITAR EN LA ARGENTINA","resumen":"Los debates que giran en torno a la violencia que se vivió en la Argentina en la década de los años ´70 del siglo XX, suponen intentos para develar creencias, valores, ideologías, memoria, formas de sociabilidad, que se orientan a dar explicaciones acerca de la historia reciente. La memoria no supone el restablecimiento total del pasado, sino una selección, pues ciertos elementos del suceso serán conservados, mientras otros van a ser progresivamente marginados y finalmente olvidados. De aquí se desprende que hay que distinguir entre la recuperación del pasado y su utilización subsiguiente. A partir de la aceptación de que la memoria es selección, ésta se hará partiendo de las informaciones recibidas de acuerdo a determinados criterios; y esos juicios, sean o no conscientes, van a servir, probablemente, para orientar la utilización que se hará del pasado. 'Sin embargo, desde otro punto de vista, de legitimidad y no ya de origen, existe una gran discontinuidad: no se puede justificar un uso engañoso por la necesidad de recordar. Nada debe impedir la recuperación de la memoria.","palabras_clave":"Género|Feminimos|Memoria|Violencia"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195050,"idioma_id":5,"titulo":"Recursos genéticos caprinos de la República Argentina.","resumen":"Desde la introducción de animales domésticos al territorio argentino porlos conquistadores españoles, los caprinos se han extendido y adaptadoa diversas regiones agroecológicas del país. En la actualidad la especiecaprina adquiere un valor relevante para las comunidades humanas, enespecial para aquellas más desprotegidas, dado el impacto social y económicoque ejercen, así como por su capacidad de adaptación a los ambientesáridos y semiáridos en que se desenvuelven, lo cual los convierten enun recurso genético de importancia para el país. En las últimas décadasse repiten sin éxito estrategias de mejora de la producción a través de laincorporación de razas caprinas exóticas de alta producción, las que no hanlogrado adaptarse y demostrar su potencial genético en áreas marginales.Es allí donde la utilización de los recursos genéticos caprinos locales setorna fundamental, y por ello afortunadamente se han iniciado tareas decaracterización con el objetivo de diferenciar, evaluar y ponerlos en valor.En varias provincias argentinas instituciones nacionales y provinciales han llevado adelante un arduo trabajo con estrecha vinculación de losusuarios de los recursos genéticos caprinos locales, avanzando hasta laobtención de productos diferenciados, en un caso hasta la denominaciónde origen. Se describen en este capítulo los aspectos relacionados con lacaracterización fenotípica, demográfica y de los sistemas de producciónde las siguientes poblaciones caprinas: la cabra criolla del norte neuquino(ccn), cabra criolla del norte de Córdoba (ccnc), la cabra colorada pampeana(ccp), la cabra criolla del oeste formoseño (cof), la cabra criolla deLa Rioja (cclr), y la cabra criolla serrana del Noa (ccs-noa). La diversidadencontrada en las cinco poblaciones descriptas, refleja la enormeriqueza actual del patrimonio caprino criollo argentino.","palabras_clave":"Conservación|Biodiversidad|Caprinos|Red CONBIAND"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195083,"idioma_id":4,"titulo":"Chemistry of hybrid multifunctional and multibranched composites","resumen":"The aim of this chapter is to illustrate, through different examples, the importanceof the design of hybrid materials and the properties obtained as a consequenceof the presence of hyperbranching and adequate functionalization. We will showprominent examples of chemical modification on different substrates (flat surfacesor curved 3D structures). As substrates, we have selected inorganic or highlycrosslinked organic polymers such as porous polymeric supports, inorganic nanoparticles,or electrodes, in order to obtain greater insight into the control and adjustabilitybased on size, architecture, and functionality. We place special emphasison structure\/property relationships and provide interesting examples of potentialapplications and uses.","palabras_clave":"hybrid structures|dendritic|hyperbranched, |functional materials|multifunctional"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195109,"idioma_id":4,"titulo":"Biotechnological production and significance of triacylglycerols and wax esters. (Update)","resumen":"Global fat, oil, and wax ester demand is forecasted to increase in the next years. Steadily growing biodiesel requirements will lead to an increased demand for vegetable oils, in combination with a constant rise in the consumption of vegetable oil as food and feed. This situation will prompt the use of alternative sources for the production of oils and wax esters during the next years. In this context, microorganisms (yeasts, fungi, microalgae, and bacteria) are receiving increasing attention as alternative oils and wax esters sources. The knowledge acquired during the last decade about the production of bacterial triacylglycerols (TAG) and wax esters (WE) and their fundamental aspects could provide a new production platform for&#8201;oils. The applied potential of bacterial TAG and WE may be similar to that of vegetable sources, such as additives for feed, cosmetics, oleochemicals, lubricants, and other manufactured products. In addition, bacterial oils could be used for biofuel production. The development of an industrial and commercially significant process may depend on the optimization of engineered cells and the technological procedures. This chapter will focus on the potential biotechnological application of TAG and WE produced by bacteria.","palabras_clave":"Applied Microbiology|Environmental Engineering\/Biotechnology"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195118,"idioma_id":4,"titulo":"An overview on microbial degradation of lindane.","resumen":"Lindane is a cyclic, saturated and highly chlorinated pesticide with a broad spectrum, which has been used worldwide for many decades to control a variety of pests, and also in human health and veterinary. Afterward, it has been demonstrated that lindane and its isomers may cause serious damage to health in the short and long term. Besides, lindane is known to be persistent in the environment and tends to bioaccumulate along the food chain. Thus, lindane residues remain in the environment for a long time and have been recently found in water, soil, sediments, plants, and animals all over the world, and even in human fluids and tissues. In this context, nowadays, scientists, working all over the world, are involved in developing lindane remediation technologies including physical, chemical, and biological techniques. This article provides updated information on the biologic degradation of lindane using different microorganisms such as bacteria, fungi, and algae, under both aerobic and anaerobic conditions.","palabras_clave":"LINDANE|MICROORGANISMS|DEGRADATION|BIOREMEDIATION"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195275,"idioma_id":4,"titulo":"Composites and nanocomposites based on starches. Effect of mineral and  organic fillers on processing, structure and final properties of starch","resumen":"Composites development by incorporating organic or mineral fillers to starch matrices can be used to improve their final properties. Accordingly, composites of different starch matrices reinforced with organic fillers, as well as, with mineral particles are described in this chapter. In this sense, it was reported the use of cellulose fibers from different botanical origins and clays particles. Nowadays, both academic and industrial interest in nanoscale fillers is growing since a nanostructured composite could be developed from a polymeric matrix and layered mineral particles. Thus, in this chapter is also included the development of nanocomposites based on thermoplastic starch and talc nanoparticles from different geological origins and morphologies. Processing methods are described and structural and final properties of composites are reported.","palabras_clave":"STARCH COMPOSITES|TALC NANOPARTICLES|BENTONITE PARTICLES|ORGANIC FILLERS|THERMAL PROCESSING|MICROSTRUCTURE|THERMAL AND OPTICAL PROPERTIES|MECHANICAL BEHAVIOR|BARRIER PROPERTIES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195312,"idioma_id":4,"titulo":"CURRENT PERSPECTIVES IN WILD PRIMATE RESEARCH IN ARGENTINA.","resumen":"In order to promote the conservation of primates in Argentina it is important to: 1. Sustain the long-term sites that already exist. The research conducted in them provides unique and important data that allow to develop management and conservation strategies for the different primate species, 2. Finish and implement the National Plan for the conservation of primates in Argentina, 3. Promote the establishment study sites for S. paraguayanus, A. guariba clamitans, and A. caraya in protected areas plus S. nigritus in unprotected areas, 4. Develop studies on genetic variability of several populations of each species. These studies will allow defining priority areas for establishing conservation units applicable to all primates in Argentina.","palabras_clave":"PRIMATE RESEARCH|ARGENTINA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195357,"idioma_id":5,"titulo":"Catolicismo político en la ciudad de Buenos Aires a comienzos del siglo XX: entre la secularización política y las sombras del clericalismo político, 1900-1919","resumen":"La  problemática de las actitudes políticas de los católicos argentinos y de sus  intentos de articulación a comienzos del siglo XX no han recibido una atención  comparable al crecimiento constante experimentado en la historiografía dedicada  a estudiar otras áreas de la historia de la Iglesia Católica en la Argentina,  si bien se ha constatado un avance creciente en los últimos años. Los intentos por  constituir agrupaciones políticas que expresaran una cierta inspiración  católica reflejaban en la Argentina (y específicamente en la ciudad de Buenos  Aires) la continuidad de una tradición que se había esbozado en el siglo XIX  como respuesta a embates anticlericales y al avance secularizador del estado. En  este artículo se pretende explorar las formas que asumiría aquella intervención  en la ciudad de Buenos Aires a comienzos del siglo XX proponiendo algunas  conclusiones referidas a las actitudes y estrategias de los católicos en relación  a las formas de hacer política dentro de los límites del llamado orden  conservador y a la adaptación de los notables y asociaciones católicas al nuevo  escenario planteado por las transformaciones observadas como consecuencia del  proceso de reforma electoral.","palabras_clave":"CATOLICOS|ANTICLERICALISMO|CLERICALISMO|SECULARIZACION POLITICA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195391,"idioma_id":5,"titulo":"El cuento de Los Dos Hermanos. Interpretación narrativo-simbólica y planos de significación","resumen":"El presente capítulo forma parte de una compilación de estudios sobre relatos de la literatura egipcia. Aquí se analiza el cuento de Los Dos Hermanos, una historia de la dinastía XIX que se conserva en el Papiro d´Orbiney. El trabajo presenta en primer lugar características generales del papiro, así como referencias a publicaciones e investigaciones desde la egiptología. Se realiza una interpretación general, a partir de la observación de sus características de estilo y del estudio de ciertos aspectos del cuento. Entre los temas particulares abordados podemos mencionar la descripción y análisis de la situación familiar, consideraciones acerca del exilio y las transfiguraciones de Bata, un planteo inicial sobre la legitimación faraónica, y la comparación con ejemplos similares de otras culturas.Cabe destacar igualmente que participé como revisora de las traducciones de los textos literarios incluidos en la compilación.","palabras_clave":"DOS HERMANOS|LITERATURA|SÍMBOLOS|SOCIEDAD"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195399,"idioma_id":2,"titulo":"Partizipatives Entwickeln","resumen":"Die akademische Disziplin der Berufspädagogik ist auf Zusammenarbeit mit Personen aus Wissenschaft und Praxis angewiesen. Die große Heterogenität der Forschungsfragen zwischen Technik, Ökonomie, Soziologie, Psychologie und Pädagogik, aber auch zwischen Betrieb, Korporationen, Schulen, Nicht-Regierungsorganisationen und Staat, d.h. ? die Vielzahl von Akteuren, Forschungsfeldern, Zuständigkeitsbereichen und Modi der Verkoppelung führt dazu, dass kaum eine Wissenschaftlerin oder ein Wissenschaftler in einem umfassenden Sinn mehr und Genaueres weiß als ihr informiertes Gegenüber.Eben diese direkte Zusammenarbeit mit der Praxis macht zugleich ein hohes Maß an Selbstreflexion erforderlich, um mit dem immanenten politischen Widerspruch umzugehen, dass die Berufspädagogik einerseits für das zu bildende Individuum Partei zu ergreifen und es zu Selbstbestimmung zu führen hat, zugleich aber ihre Aufgabe darin sieht, für die Tätigkeit in häufig fremdbestimmten Arbeitsverhältnissen zu ertüchtigen.Partizipatives Entwickeln ist ein Forschungsansatz, der die Spannungsfelder, die sowohl aus der Interdisziplinarität als auch aus dem genannten Zielkonflikt entstehen, aufzulösen versucht, indem Lösungsansätze für und gemeinsam mit handelnden Subjekten in der Praxis entwickelt werden. Wir fassen dabei unter Partizipatives Entwickeln denjenigen Teilbereich teilnehmender Forschung, der auf die Entwicklung neuer Strukturen, Verfahren oder Prozesse angelegt ist. Wissenschaftlerinnen und Wissenschaftler leisten diese Entwicklungsarbeit durch ihre aktive Expertise gemeinsam mit den Akteuren aus dem Forschungsfeld.","palabras_clave":"INVESTIGACIÓN PARTICIPATIVA|EDUCACIÓN|TRABAJO|ETNOGRAFÍA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195458,"idioma_id":4,"titulo":"Indigenous Children In and Out of Schools","resumen":"This is a moment in the history of educational research when scholars are beginning to recognize that research conducted in only one country cannot fairly represent the meanings and trajectories of education in the world as a whole. There are new efforts?often spurred by researchers from the global South?to take all voices into account (e.g. Bagchi et al. 2014; Connell 2007; Manzon 2011). The edited volume we propose, Comparing Ethnographies: Toward an Ethnology of Education across the Americas, is part of that emerging movement, and would be seen as particularly significant if published by AERA from the center of educational research in the global North.   The proposed volume, focused on ethnographies of education as conducted in Latin American countries on the one hand and in the United States on the other, aims to show what can be learned by comparing research across national and linguistic boundaries. It will also ask how other scholars can carry out such comparative work in spite of the challenges inherent in the task. The book aims to convince readers that work done in all parts of the hemisphere is significant and needed to expand the boundaries of their own research and theorizing, and that finding and using that work is feasible. Our long-term goal is to contribute toward building an ?ethnology of education? of global applicability, that is, an anthropologically and sociologically informed understanding of education grounded in ethnographic cases and stretching beyond the national borders that often limit the international relevance of educational research.    The core of the volume consists of five co-authored chapters that compare key ethnographic studies done in two or more countries, seeking to understand both the different contexts in which they were done and the different approaches that scholars used in studying similar educational problems. The authors of each chapter had not previously worked with each other, so had to face challenges in crossing both linguistic, discursive and conceptual boundaries in order to do comparisons. These exercises attempt both to apply existing methodological guidelines for comparison and to offer new insights and guidance for future comparative ethnography?and indeed all comparative educational research.","palabras_clave":"ETHNOGRAPHY|COMPARATIVE STUDIES|ETHNOLOGY OF EDUCATION|AMERICA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195489,"idioma_id":5,"titulo":"Creatividad y ontología","resumen":"La creatividad es sin lugar a dudas una de las capacidades más representativas y propias del ser humano. Talento, capacidad inventiva, originalidad, genialidad. Poesía, pintura, escultura, literatura, música, ideas, teorías científicas, mitos, religiones, inventos tecnológicos, hasta platos gastronómicos. Todos estos conceptos caen dentro del campo semántico de lo que, usualmente, asociamos con el ser creativo, con la creatividad humana. Pero, ¿qué es lo que nos hace creativos?, ¿de dónde proviene tal maravillosa capacidad? Tradicionalmente, la creatividad fue asociada con las producciones artísticas que representaban a las élites políticas o religiosas de una cultura. Su romántico fundamento, se alegaba, provenía de la inspiración súbita, de la epifanía proveniente de seres alumbrados por un halo de divinidad o motivados por la naturaleza misma. Immanuel Kant afirmaba, por ejemplo, que el 'genio', como talento innato y responsable de la producción del arte bello, era el medio por el cual el artista creador era guiado de manera inconsciente e involuntaria por reglas que la naturaleza misma dictaba. Todo arte bello, para Kant, era inexplicable en algún punto, e irreproducible en otro; en la misma medida en que el arte resultaba bello y creativo, era familiar cercano de la naturaleza misma.  Frente a las explicaciones románticas y puramente individualistas de la creatividad humana, que la singularizaban en la figura sublime de genio, los enfoques socioculturales han hecho su aparición e impuesto su sello. Más allá de la indudable inspiración individual, se hace cada vez más innegable el papel que la sociedad y la cultura juegan en todo proceso creativo. A todo invento subyace una sociedad entera, con sus contradicciones y fortalezas; a toda obra de arte subyace un completo movimiento de ideas y tendencias de una generación. Los estudios de cultura comparada y antropología sociocultural ampliaron, a su vez, el espectro de aquello que llamamos 'creativo'. La visión occidental y decimonónica de la creatividad, restringida a un selecto repertorio europeo, es progresivamente abandonada dando paso a un enfoque verdaderamente universal y humano de la creatividad, donde el Arte de la Fuga de Bach convive con las pirámides de Teotihuacán. Progresivamente, la creatividad y todos los productos humanos asociados a ella se convierten en baluartes de la humanidad, aunque histórica y culturalmente especificables, mutando de sentido a medida que recorremos años y lugares. Sin embargo, ¿hasta dónde podemos extender el campo de lo creativo? No vacilamos al incluir dentro de este campo los innumerables ejemplos artísticos, arquitectónicos y literarios de cada cultura y época histórica. Tampoco caben dudas acerca del genio inventivo que yace detrás de la máquina a vapor, producto del visionario James Watt y la pujante sociedad inglesa en plena revolución industrial. Usualmente, una idea que revoluciona nuestra visión del mundo también es llamada 'creativa', como las nociones de espacio y tiempo propuestas por la teoría de la relatividad (especial y general). El concepto de creatividad o 'ser creativo' es sumamente complejo y multifacético, escapando a cualquier definición que permita, de manera unívoca, determinar qué entra dentro de su campo de aplicación y qué no. Pero, ¿hasta dónde correr los grises y difusos límites de lo que llamamos creativo? Una teoría científica, ¿es producto de la creatividad humana? ¿Lo es un modelo computacional? ¿Y un libro de historia natural? La respuesta no parece tan evidente en todos los casos.","palabras_clave":"Creatividad|Ontologías múltiples|Espacio-tiempo|Dimensionalidad"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195515,"idioma_id":5,"titulo":"Morteros de argentina. Miradas desde y hacia la arqueología de los siglos XIX y XX y prospectos para futuros estudios","resumen":"The purpose of this paper is to visit the various approaches developed on dimpled stones, or large rocky substrates with holes, which have been known as fixed mortars in the Argentine Northwest, from the traditional perspectives of the pioneers of the national archeology, at the late nineteenth century, to subsequent studies carried out around the first half of the twentieth century. At the same time, we take a look at the concepts used by these archaeologies, through their approaches to the grindstones. Early nomenclatures and subsequent derived terminology are revisited. Some continuities between current and previous works are highlighted. Finally, the value of early studies as sources of expectations for modern analysis of artifacts and milling practices, is sustained, within the framework of the current and future challenges of the theme.","palabras_clave":"MORTEROS|ARQUEOLOGÍA ARGENTINA|PRÁCTICAS SOCIALES|SIGLOS XIX Y XX|PIEDRAS TACITAS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195517,"idioma_id":5,"titulo":"La movilidad en cuestión. Aportes para un diálogo interdisciplinario","resumen":"El presente capítulo se propone realizar una identificación de los distintos abordajes al fenómeno de la movilidad urbana presentes en la actualidad en el ámbito académico de la región y de Argentina. Como veremos, salvo algunas excepciones, no es fácil encontrar enfoques teórico metodológicos que permitan organizar investigaciones empíricas cuantitativas y cualitativas, sino más bien miradas que otorgan centralidad a un aspecto en detrimento de otros.","palabras_clave":"Movilidad urbana|Estado del arte"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195518,"idioma_id":5,"titulo":"Movilidad y subjetividad. Viajes y experiencias del espacio en los bordes de la ciudad","resumen":"Sostenemos que vivir en una ciudad metropolitana pone inexorablemente a los desplazamientos en el centro de la escena cotidiana y a lo largo de este libro, hemos aportado elementos para el análisis de los contextos, las condiciones, lasprácticas y las sociabilidades que les son propias. En este capítulo procuramos iluminar lo que los actores sociales piensan y hacen mientras éstos se planean o suceden, así como las representaciones sobre sus lugares de residencia y el espacio urbano más amplio que los desplazamientos conectan material y simbólicamente.","palabras_clave":"Movilidad|Subjetividad|Experiencias metropolitanas|Conurbano Bonaerense"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195529,"idioma_id":2,"titulo":"Percepción, narración y lectura en el prisma textual: hacia una definición de lo fantástico y su aplicabilidad a la obra de Adolfo Bioy Casares","resumen":"El objetivo general del presente artículo es revisar e interpretar transversalmente algunas de las definiciones generales de lo fantástico, a partir de sus propios presupuestos, funciones y finalidades, a fin de ver su alcance y aplicación a la obra novelística de Adolfo Bioy Casares, y, específicamente, en sus novelas: La invención de Morel y El sueño de los héroes, para comparar el funcionamiento y uso de los procedimientos  que construyen lo fantástico en estos textos, aunque no necesariamente los definen como tales. Simultáneamente, intentaremos dar cuenta de los análisis de la obra de dicho autor dedicados al tema, a fin de recortar nuestra posición en el contexto de su análisis. De esta forma, la revisión crítica del uso de 'lo fantástico' en nuestro corpus nos permitirá proponer una lectura del mismo con la ayuda de otras categorías literarias generales, con las que se relaciona la construcción de lo fantástico en la novelística de Bioy Casares. Nuestro abordaje recorta sólo aquellos interrogantes que permiten leer la especificidad de lo fantástico en la obra del autor y de acuerdo con su propia construcción, antes que en términos netamente teóricos.","palabras_clave":"Literatura fantástica|Bioy Casares|Lectura|Narración"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195656,"idioma_id":4,"titulo":"Disruption of pollination services by invasive pollinator species","resumen":"Plant?pollinator interactions and associated pollination services are essential for crop production and the integrity of terrestrial ecosystem services. Introduced pollinators, in particular social bees like honeybees and bumblebees, have become invaders in many regions of the world, strongly affecting the pollination of native, cultivated, and non-native plants. These effects can be ?direct?, when invaders interact with local flowering plants, or ?indirect?, when invaders modify the interaction of native pollinators with flowering plants. Direct effects on pollination depend on whether the plant benefits from the flower visits are greater than their costs, a relation that can be density-dependent. Shifts from mutualism to antagonism occur when invasive pollinators reach extremely high densities, because interaction costs exceeds benefit. Indirect effects depend on whether pollinator invaders alter the benefit?cost of native pollinator visits, displace them, or trigger reductions in native pollinator diversity. Through a literature review we found that the impacts of invasive pollinators on pollination were predominantly negative for native plants, mixed for crops, and positive for invasive plants. Furthermore, they can synergistically interact with other stressors on pollination like climate change and habitat disturbance. Although invasive pollinators can backup pollination of some native plants in highly disturbed habitats, and some crops in intensively modified agroecosystems, they cannot replace the role of a diverse pollinator assemblage for wild plant reproduction and crop yield. Hence, managing agroecosystems for enhancing wild pollinator diversity, and avoiding further introductions of non-native pollinators are realistic cost-effective measures for the provision and stability of pollination services.","palabras_clave":"APIS|BOMBUS|INTRODUCED POLLINATORS| INVASIVE SPECIES|POLLINATION SERVICE"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195682,"idioma_id":4,"titulo":"Meteorological Drought Indices: Rainfall Prediction in Argentina","resumen":"There are many meteorological indices being used to detect the climate atmospheric and oceanic forcing. Some of them are hemispheric and represent climate forcing associated with changes in atmospheric circulation, which drive rainfall anomalies in different parts of the earth. They are known as ?teleconnections? and the most relevant is the El Niño?Southern Oscillation. Other indices are defined near the area to detect the possible causes of rainfall anomalies; they are closely related to the regional circulation patterns, like mountains or local winds. The challenges of a changing climate increase the need to continue working toward the development of better indicators and methods to monitor rainfall in different parts of the world. Rainfall behavior becomes important for regional economies, especially in agricultural resources and hydrological energy generation, among other activities. The aim of this chapter is to identify some of the meteorologicalindices that are actually being used and their development and uses in Argentina.","palabras_clave":"PRECIPITACION|PRONOSTICO ESTACIONAL|FORZANTES CLIMATICOS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195742,"idioma_id":5,"titulo":"Marcas subjetivas.  Racismo y discriminación en la trama educativa","resumen":"Investigar la convivencia, la conflictividad y las violencias en la trama educativa requiere abordar la dimensión socio-psíquica, corporal y emocional de la subjetividad. Ello significa correr el velo y visibilizar las formas en que se instituye lo social, simbólica y materialmente, en la afectividad y en la corporeidad. Entendiendo que las emociones y los cuerpos han sido históricamente objetos de estudio prácticamente ausentes  en el campo de investigación en las Ciencias Sociales, y más particularmente en la Sociología de la Educación, se torna pertinente la promoción de nuestra línea de investigación sobre la construcción social de las emociones en la vida escolar. Es a partir de la consolidación de los Estados y la monopolización de los mecanismos de la violencia que se ejerce control externo e interno de las experiencias emocionales de los sujetos. En el proceso civilizador, con el control progresivo de emociones tales como la vergüenza, el miedo, el desagrado o la humillación, el cuerpo juega un papel cardinal. Nos interesa analizar la trama vincular de la cotidianeidad escolar -mediatizada por discursos, imágenes y prácticas- en lo concerniente a los procesos de estigmatización y de inferiorización que operan en la construcción de subjetividad y en la constitución de lazos sociales. Estamos en condiciones de afirmar que hemos consolidado un trabajo de indagación teórico con base empírica sobre las relaciones entre escuela y violencias desde la perspectiva de los jóvenes estudiantes; haciendo foco en la dimensión simbólico-subjetiva de lo social.  A través de la realización de focus groups (entrevistas grupales) en escuelas públicas urbano-marginales de la Provincia de Buenos Aires, Argentina, exploramos los mecanismos de producción de la violencia y las transformaciones de las experiencias emocionales en contextos de exclusión social. Partiendo del supuesto de que la afectividad no puede ser reducida al despliegue de una interioridad individual. Toda emoción es, por principio, una dimensión relacional, histórica y situada.","palabras_clave":"EMOCIONES|CUERPOS|VIOLENCIAS EN LA ESCUELA|ESTIGMATIZACIÓN"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195768,"idioma_id":5,"titulo":"Estrategias campesinas en contextos de avance capitalista en la región pampeana","resumen":"El propósito de este capítulo reflexionar en torno a las estrategias campesinas en el contexto actual de expansión capitalista en Argentina. Se conciben a las estrategias como construcciones sociales producto del sentido práctico de los sujetos. Son acciones y formas de percepción realizadas en forma permanente que permiten el desarrollo de procesos de producción-reproducción de los grupos (Bourdieu 2014 [2006]). La capacidad de acción, intervención y de movilidad de recursos depende de la posición de los sujetos en el campo social, la lógica del mismo y las situaciones particulares en las se encuentren comprometidos (Gutiérrez 1998). En este marco, a través de un estudio de caso, se buscan reconstruir las estrategias de reproducción social puestas en acción por campesinos de dos parajes rurales del Oeste de La Pampa, Argentina. Frente al avance del capital, cabe interrogarse qué posibilidades de persistir poseen estos sujetos y qué perspectivas pueden esbozarse en función de posibles escenarios futuros.Para la reconstrucción de las estrategias el trabajo se enmarca en el paradigma interpretativo. Se combinan diferentes técnicas de metodología cualitativa que articulan historias de vida con entrevistas en profundidad y análisis de fuentes documentales, cartográficas y estadísticas. A continuación se realiza un breve mapeo teórico de las principales líneas de interpretación sobre el campesinado en el capitalismo actual y las posibles tendencias en un escenario de avance capitalista.","palabras_clave":"AGRONEGOCIOS|ALTERNATIVAS|MODELOS|DESARROLLO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195773,"idioma_id":4,"titulo":"A Plea for an Historical Anthropology of Ancient Palestine","resumen":"The following arguments and thoughts deal with an interpretive direction that, although already advanced in some recent works within the field of Old Testament studies and the archaeology of the southern Levant,  it deserves to be fully expanded and realised: a socio-anthropological understanding of historical processes in ancient Palestine during the first millennium BCE that successfully overcomes the shortcomings found in standard 'histories of ancient Israel' and their almost exclusive attention to Old Testament-related themes and events.","palabras_clave":"ANCIENT PALESTINE|HISTORICAL ANTHROPOLOGY|HEBREW BIBLE|HISTORIOGRAPHY"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195949,"idioma_id":4,"titulo":"Transport phenomena in biodegradable and edible films","resumen":"The transport properties of edible films and coatings play a key role in reducing, deceleration and improving the exchange of substances between the coated food and its surrounding environment. This chapter describes the fundamental aspects of mass transfer phenomena and the applicable methods for characterization and evaluation. It also gives an introduction to the mathematical methods based on finite elements, which are used as a means to simulate and predict mass transfer.","palabras_clave":"Edible and biodegradable films|Finite element methods|Mass transport|Transport phenomena"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195960,"idioma_id":5,"titulo":"El desafio de incorporar frutos del bosque semiárido a sistemas productivos rentables","resumen":"El trabajo presenta las potencialidades de los frutos silvestres de algunas leguminosas arbóreas, especies del género Prosopis, Ziziphus y Geoffroea, ampliamente difundidas en el Gran Chaco Americano, particularmente en el Noroeste Argentino. Los frutos de estas especies fueron ancestralmente empleados por comunidades rurales y aborígenes, por sus múltiples usos como recursos alimentarios, medicinales y tintóreos y como piensos para el ganado. Sin embargo, a pesar de sus potencialidades y de la profundización de los estudios, en  las últimas dos décadas, al respecto de sus cualidades nutricionales y posibles incorporaciones en procesos productivos, aún no se consolidaron sistemas efectivos a escala semi-industrial o industrial. En este sentido, se realizó un análisis de los distintos factores que se detectaron como posibles causales del actual estado de situación, los puntos críticos comunes de los distintos procesos productivos, las investigaciones realizadas y las que aún faltan profundizar, el desarrollo de tecnologías adecuadas para las líneas de trabajo, la articulación de distintos actores; pobladores rurales, instituciones públicas y privadas; y una breve reseña de aspectos referidos a la comercialización y mercado de los productos. El capítulo es el resultado de las investigaciones y experiencias de los autores del trabajo y de la revisión bibliográfica sobre el tema.","palabras_clave":"FRUTOS|CHACO ARGENTINO|SISTEMAS PRODUCTIVOS|ARTICULACIÓN INSTITUCIONES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195972,"idioma_id":4,"titulo":"Mycorrhizas across successional gradients","resumen":"Ecological succession has been widely studied for over a century, yet the focus has mainly been on plant community dynamics over time. In the last two decades there has been a steady increase of research focused on mycorrhizal fungal succession, in part due to methodological advancements. In this chapter, we first review mechanisms of mycorrhizal succession in terms of ?habitat?, ?plant?, and ?fungal? drivers. Habitat drivers point to the importance of soil pH, phosphorus (P), nitrogen (N), and moisture during primary and secondary succession while P availability and soil pH are more important during long-term pedogenesis and at large spatial scales. Plant drivers such as size and age of root systems and host plant identity are often identified as important factors structuring and diversifying mycorrhizal fungal communities. Fungal drivers can also be important; mechanisms such as dispersal limitation of fungi can strongly influence the composition of ectomycorrhizal fungal communities and shows considerable spatial and temporal dependencies. We conclude that no single driver rules them all; instead the drivers interact and the relative importance of each driver depends on the spatial and temporal scales. We propose the ?Interacting drivers? hypothesis to highlight the importance of interactions between drivers. We also highlight promising topics and approaches for future research that should increase our understanding of the ecology of the mycorrhizal symbiosis but also better inform models of carbon sequestration and climate change.","palabras_clave":"Mycorrhizal fungi|Community ecology|Soil properties|Causal statistics"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195976,"idioma_id":5,"titulo":"Conservación del águila coronada (Harpyhaliaetus coronatus) en Argentina: amenazas, situación actual y lineamientos para una estrategia de conservación de la especie.","resumen":"El águila coronada (Harpyhaliaetus coronatus) es una de las rapaces de mayor tamaño de las que habitan la región semiárida y central de la Argentina y el sur de Sudamérica. Su distribución alcanza desde el sur de Brasil hasta el norte de la patagonia Argentina y está considerada como una especie en peligro de extinción a nivel nacional e internacional, con una población mundial estimada entre 250 y 1000 individuos. A pesar de su amplio rango de distribución, diversos aspectos de la biología y ecología de la especie son aún desconocidos y muchos de ellos se encuentran directamente asociados a las causas de su actual estado de conservación. Actualmente se desarrollan tareas de investigación y actividades de extensión y educación en solo algunas provincias comprendidas dentro del rango de distribución de la especie, existiendo un gran vacío de información sobre la ecología de la especie y de las amenazas que podrían sufrir sus poblaciones para una gran parte de los biomas del país donde la especie ha sido registrada. En la provincia de La Pampa la especie es perseguida por considerar que preda sobre el ganado doméstico, aspecto que no ha sido reflejado en los estudios sobre los hábitos de alimentación de la especie realizados hasta el momento. Sin embargo, y aún cuando este conflicto existiera en el pasado, la actitud y percepción negativa hacia la especie por parte de los pobladores locales persiste actualmente. Se han registrado casos de electrocución de grandes águilas, incluyendo al águila coronada entre las especies afectadas, en tendidos de distribución de energía tanto en Mendoza como en La Pampa. En los últimos años se han realizado una serie de talleres con el fin de acordar un Plan de Acción para la conservación del águila coronada en Argentina, acordándose entre los especialistas las prioridades de conservación e investigación en base a las principales  amenazas para la especie: pérdida de hábitat, persecución directa, electrocución con tendidos eléctricos y la expoliación de nidos y tráfico ilegal. Los resultados de estas reuniones e investigaciones han puesto de relevancia la necesidad de generar información básica necesaria para el manejo efectivo de la especie, incluyendo aspectos de su distribución, abundancia, diagnóstico de amenazas y ecología básica. Aunque la cría en cautividad no se plantea como una acción prioritaria, otras acciones de conservación ex-situ, como la recuperación y liberación de individuos rehabilitados, pueden servir para reforzar poblaciones silvestres cuando la procedencia de los mismos y origen esté debidamente documentada. Las tareas de investigación, sumadas a un fuerte componente de educación y extensión en cada una de las áreas donde se identifiquen poblaciones estables de la especie, son medidas prioritarias y fundamentales para establecer las bases de un programa de conservación del águila coronada en Argentina.","palabras_clave":"Águila coronada|Harpyhaliaetus coronatus|Amenazas|Conservación"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":195979,"idioma_id":5,"titulo":"El argumento como dato","resumen":"El libro es el producto del primer congreso del instituto Medios y Sociedad y compila el material discutido en la Universidad de San Andrés en el año 2015","palabras_clave":"medios|periodismo|innovacion|agendas"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196047,"idioma_id":10,"titulo":"Perfeccionismo y burnout.","resumen":".","palabras_clave":"Perfeccionismo |Burnout"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196098,"idioma_id":4,"titulo":"Urbanization and bird communities: Spatial and temporal patterns emerging from southern South America","resumen":"Urbanization is an expanding process worldwide, and South America seems to follow the general pattern observed in more urbanized regions of the world. Most conceptual models on the response of biodiversity to urbanization, however, are based on the experience in developed economies. In this chapter, we summarize patterns of bird communities found at different spatial and temporal scales in southern South America. Along a 1,400-km latitudinal gradient we found that urbanization: 1) obscured the latitudinal pattern of bird species richness, 2) had a stronger negative effect on bird richness in tropical than in temperate or arid regions, and 3) resulted in more similar communities than the seminatural or rural areas, suggesting a process of biotic homogenization. The analysis of urban centers of different sizes indicated that bird richness and abundance were negatively affected by urbanization only in cities above 7,000 and 13,000 inhabitants, respectively. In the Pampean region, urbanization affected negatively birds that nest on the ground, with insectivorous and carnivorous diets, feeding on the air and on vegetation and with solitary and migratory behaviors. Urbanization decreased the seasonal and interannual variability of bird species composition. We suggest future directions of research on the influence of latitude on temporal dynamics of bird communities in urban areas, comparison of bird responses to urbanization among biogeographical regions using a mechanistic approach, and including functional and phylogenetic diversity as response variables in the analyses.","palabras_clave":"urbanization|Neotropic|birds|conservation"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196132,"idioma_id":5,"titulo":"Moral","resumen":"Si  bien pueden reconocerse usos triviales del término 'moral' en la lengua castellana  ('el equipo tiene la moral muy alta', 'el ejército no tiene la moral baja pero  hay inquietudes'), existen dos usos centrales que serán analizados  detalladamente: el uso descriptivo y el uso normativo. El objetivo de esta entrada es definir y diferenciar entre ambos.","palabras_clave":"MORAL|ETICA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196152,"idioma_id":5,"titulo":"Liderazgo, popularidad, emotividad. Evaluación de la hipótesis de un populismo macrista","resumen":"En ocasión del triunfo electoral de Mauricio Macri, circuló en el debate intelectual y en el discurso público la idea de que la construcción política que lo condujo a la presidencia lo acercaba en cierta medida al populismo o, cuanto menos, que presentaba algunos tintes populistas. Esta caracterización permitía avanzar ciertas hipótesis generales relativas al vínculo emocional que el nuevo presidente habría de trabar con sus adeptos. En este capítulo, interesa ponderar los componentes populistas del lazo político articulado por el nuevo presidente. Esto permitirá ganar claridad respecto de la dimensión emotiva específica a la articulación política macrista.","palabras_clave":"populismo|liderazgo|carisma|emociones"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196165,"idioma_id":10,"titulo":"Introdução: a questão urbana, hoje","resumen":"En este capítulo se recuperan las tradiciones actuales y los debates actuales en torno a la cuestión urbana hoy.","palabras_clave":"CUESTIÓN URBANA|DESIGUALDAD"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196166,"idioma_id":5,"titulo":"Dinámicas territoriales en la producción de la desigualdad de Buenos Aires","resumen":"Este escrito tiene por objetivo contribuir a la comprensión del modo en el que se producen las desigualdades sociales en Buenos Aires. Para ello nos centraremos en las dinámicas territoriales de la ciudad que se expresan, en parte, en los modos conflictivos de construcción y apropiación desigual del espacio urbano. Se analizan tres postales en las que&nbsp;es posible observar las dinámicas, narrativas y procesos de interacción social entre diferentes grupos sociales a través de y en los que las desigualdades se (re)producen:&nbsp;la ocupación de tierras en el parque Indoamericano en el sur de la ciudad a fines2010, la presencia de recolectores informales de residuos en las calles de los barrios de clase media y alta y&nbsp;la&nbsp;existencia de personas en situación de calle en los barrios céntricos de la ciudad.&nbsp;En la primera de las postales nos centramos en el habitar y nos adentramos en los&nbsp;conflictos por el acceso al suelo urbano. En el segundo caso, es el circular por la ciudad lo que se pone en el centro de indagación. Nos enfocamos aquí en los modos en los que ciertos grupos sociales acceden (o buscan hacerlo)a la ciudad de Buenos Aires, en las pugnas por el uso del espacio, en el modo en que se construyen la territoralidad y los órdenes urbanos. En el tercero, abordamos las dinámicas concomitantes del circular y el habitar tomando como base la experiencia de las personas en situación de calle.","palabras_clave":"DESIGUALDAD URBANA|BUENOS AIRES|TOMA DE TIERRAS|CIRUJEO|PERSONAS EN SITUACIÓN DE CALLE"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196222,"idioma_id":4,"titulo":"Electroless plating of  Pd binary and ternary alloys and surface characteristics for application in hydrogen separation","resumen":"Electroless plating has been defined as a controlled autocatalytic deposition of a continuous layer on a catalytic surface by the reaction of a complex compound and a chemical reducing agent. This method allows the easy preparation of films using simple equipment and any type of support with low thickness.Palladium based layers are able to separate hydrogen selectively because of the high solubility and diffusivity of hydrogen atoms in their lattice. The electroless deposition and characterization of Pd based binary and ternary alloys are discussed taking into account their superior properties concerning hydrogen permeability and\/or chemical resistance.","palabras_clave":"COMPOSITE MEMBRANES|PALLADIUM TERNARY ALLOYS|PALLADIUM BINARY ALLOYS|SURFACE SEGREGATION"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196224,"idioma_id":4,"titulo":"Disadvantages of Starch Based Materials, Feasible Alternatives In Order To Overcome These Limitations","resumen":"It is well-known that starch based materials are hydrophilic and water-soluble. Even though, water solubility raises degradability and increases degradation speed; this moisture sensitivity limits their industrial applications. Thus, in this chapter the main disadvantages of starch based materials are well described, especially those related to their poor mechanical behavior and high water vapor permeability.  Within this context, several options to solve these drawbacks are also introduced in order to widespread their industrial and commercial applications.","palabras_clave":"Starch, |WVP|Mechanical properties, | Processability"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196228,"idioma_id":4,"titulo":"Polyelectrolyte-drug ionic complexes as nanostructured drug carriers to design solid and liquid oral delivery systems","resumen":"Aqueous dispersions of acid or basic polyelectrolytes (PE) loaded with ionizable drugs (D) of opposite charge are characterized by a high degree of counterionic condensation. In solid state, these PE-D complexes are stable amorphous materials that, in many cases, quickly swell reverting to the original dispersion in the presence of aqueous fluids. Such systems exhibit a set of unique properties. Among them, the reversibility of the PE-D association modulates the release of D when dispersions are in contact with biological fluids. Besides, some of them exhibit interesting bioadhesive properties. By compaction of solid complexes swellable PE-D matrices (SPDM) are obtained. Kinetics and rate of D delivery from SPDM can be modulated by changes in their composition to satisfy the design of extended delivery systems. Among the factors that control the delivery of D, the rate of swelling, complex dissociation of ionic pairs and further diffusion of D, as well as hydrogel layer erosion, are mainly involved. PE-D complexes formulated as matrices, multiparticulate ordispersed systems play an important role in the design of drug delivery systems.","palabras_clave":"POLYMERS|POLYELECTROLYTE|DELIVERY SYSTEMS|COUNTERIONIC CONDENSATION|POLYELECTROLYTE MATRIX"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196253,"idioma_id":4,"titulo":"Influence of protein conformation on the properties of soybean protein edible films","resumen":"ver Full text","palabras_clave":": soybean protein based films,   |soybean protein isolates,|protein conformation,|structure ?functionality relationship,| active release film."},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196267,"idioma_id":4,"titulo":"La Plata River\/Río de la Plata Estuary","resumen":"The La Plata River system can be defined as a funnel coastal plain tidal river with a semi-closed shelf at the mouth. La Plata River is both the world?s widestfreshwater system and an estuary that drains the second largest basin in SouthAmerica and the fifth largest in the world. The Rio de la Plata system is shared by Argentina and Uruguay and has an area of 38,000 km2, extends almost 300 km inlength, and widens from about 40 km at the inner freshwater part to 227 km at the Atlantic Ocean boundary. The system is mainly formed by the Paraná andUruguay rivers that provide 97 % of the water discharge contributing with amean annual flow of 16,000 and 4,000 m3\/s, respectively. The Rio de la Platacomprises three well-defined areas: the internal zone that starts at the end of the Parana Delta and is characterized by only freshwater, an intermediate or mixing zone, and an external or marine zone.","palabras_clave":"Wetlands|Río de la Plata"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196274,"idioma_id":4,"titulo":"GENETIC VARIABILITY IN ARGENTINEAN HOWLER MONKEYS (Alouatta caraya): A NATURAL PROCESS OR AN ANTHROPIC EFFECT?","resumen":"Black and gold howler monkeys (Alouatta caraya) are the most southerly primates t in the Neotropical region. Currently, they are threatened by the process of forest loss and fragmentation induced mainly by the expansion of the agricultural frontier  notably for cattle ranching and soy production. Previous studies suggest that habitat fragmentation modifies the dispersal patterns of black and gold howler monkeys, and might reflect a trend towards a reduction in their ability to disperse. Howler monkeys are very important from an epidemiological point of view because they are considered sentinels of yellow fever virus. Populations of this species have been seriously threatened by the yellow fever virus, with reported deaths in Argentina and Brazil. In the current study, we present preliminary results on a study of the genetic variation in several black and gold howler populations in Argentina. We studied nine A. caraya populations from various provinces of northern Argentina, and one population from Paraguay. With the aim of characterizing the level of genetic variability, and the processes that determined the actual genetic structure, we analyse eight already-described microsatellites or STRs (short tandem repeats). We found significant differences between populations (FST= 0.105, p<0.001). However, our analysis showed that there are some populations that share genetic characteristics and that these could be pooled as clusters. These populations are connected by rivers and riparian forests suggesting that dispersion may had taken place through them.Contributing to the biological knowledge of the genus Alouatta, our results have direct and important applications in the field of conservation, allowing the of defining priority areas for establishing conservation units for  A. caraya.","palabras_clave":"Alouatta caraya|population genetics"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196316,"idioma_id":4,"titulo":"Recasting diversity in language education in postcolonial, late-capitalist societies","resumen":"Social realities of increasing (super)diversity, mobility and the corresponding high valuation of linguistic competences and skills are currently not developing - as was expected - into egalitarian systems and structures in multilingual communities. Where such communities are characterized by linguistic hybridization, some form of recognition of the changing social contexts would have seemed reasonable. However, to the contrary, much evidence has been put forward that shows how former inequalities, prejudices and social and linguistic hierarchies are still active and even amplified in many apparently liberal societies today. Thus, in spite of the discourses celebrating multilingualism becoming more and more commonly reproduced and globally supported, they have not necessarily changed the way multilingualism is managed in schools, and in other social domains. This paper will pay attention to examining how various late capitalist and postcolonial regimes recast new forms of diversity into old moulds through the implementation of language education policies and programs. In what follows we will explore the main forces and processes of which some simply continue outdated dispensations while others are new even if still not bringing fundamental change. This is done as a means of explaining the current shape and role of diversity in language education, that is in recasting diversity within changed societal forms.","palabras_clave":"PLURILINGÜISMO|EDUCACIÓN|POSTCOLONIALISMO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196470,"idioma_id":4,"titulo":"Soybean response to pest attack","resumen":"Soybean (Glycine max), the most important legume crop in South and North America, is attacked by different insect pests that decrease crop yield. Plants have evolved sophisticated signaling networks that allow them to perceive and to cope with leaf herbivory. Herbivore attack alters levels of defensive phytohormones jasmonic acid (JA), salicylic acid (SA) and ethylene (ET) in plants, resulting in a reconfiguration of their transcriptomes and proteomes. Leaves damaged by chewing herbivores accumulate chemical defenses, such as proteinase inhibitors (PIs), polyphenol oxidase, isoflavonoids or alkaloids. Although damage is perceived by plants through mitogen-activated protein kinases (MPKs) that induce defense responses against herbivores, the response can change in accordance with the attacked organ. Interestingly, some insects prefer to feed only on certain organs and plant parts, like caterpillars feed on leaves and stink bugs on pods.  Here we explain the mechanisms that regulate the triggered responses produced by different insect pests on soybean organs. Understanding the specific responses of plant organs to insect pests will help to develop more tolerance crops to insects.","palabras_clave":"SOYBEAN|HERBIVORY|SIGNAL TRANSDUCTION"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196616,"idioma_id":5,"titulo":"Régimen de Bienes del Matrimonio (Caps. XXV - XXVI - XXVII)","resumen":"Aclaración: La obra ha sido recientemente publicada y los ejemplares están en vía de distribución a los coautores (Julio 2017). Mi contribución son 3 capítulos de un total de 500 páginas.CAPÍTULO XXVEFECTOS PATRIMONIALES DEL MATRIMONIOI. CONCEPTOS GENERALES548. DefiniciónEl matrimonio produce, como hemos analizado precedentemente, efectos jurídicos de carácter personal e igualmente efectos jurídicos de carácter patrimonial; de estos últimos nos vamos a ocupar a con-tinuación.Régimen patrimonial del matrimonio es el conjunto de relaciones jurídicas de naturaleza patrimonial que el matrimonio establece entre los esposos y de éstos con respecto a terceros  .Como se advierte hay una doble relación:a) Interna entre los esposos. Las obligaciones que se derivan varían según el régimen económico adoptado. Tal la naturaleza de los bienes (propios y o gananciales o personales), la forma de soportar los gastos o cargas. La gestión de los bienes de cada uno de los esposos. La forma de extinción y liquidación .La forma de disolución y liquidación de la sociedad conyugal.b) Externa de los esposos en relación con los terceros. La legislación persigue como fin mantener en forma equilibrada el vínculo que puede haberse generado ya por los cónyuges, ya por la comunidad, con los terceros, de manera tal que se salvaguarde el interés patrimonial de éstos.549. Clasificación de los regímenes patrimonialesLos regímenes patrimoniales han pasado en la historia del derecho diversas etapas, según el estatus jurídico que tenían la mujer y el varón en razón del matrimonio.","palabras_clave":"FAMILIA|MATRIMONIO|REGIMEN DE BIENES|NUEVO CODIGO CIVIL Y COMERCIAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196640,"idioma_id":4,"titulo":"Bacterial Endophytes of Plants: Diversity, Invasion Mechanisms and Effects on the Host","resumen":"Plant inner tissues are colonized by bacterial organisms known as endophytes. The relatively recent application of culture independent and molecular high throughput techniques allowed the description of a large diversity of endophytic bacterial taxa. These microorganisms can be found in any plant organ, including fruits and legume nodules. Some endophytic bacteria benefit the host by several mechanisms, and their application to economically important crops represents an interesting alternative to the use of agrochemicals. However, more studies are required to clearly assess their effects on the hosts (especially in co-inoculation with other beneficial bacteria) and the molecular events that lead to the interaction between plants and endophytic microorganisms. In this chapter, we focus on bacterial endophytes from legumes and non-legumes plants, analyzing their diversity and effects on the hosts. We also discuss the endophytic colonization of legume nodules, with emphasis on the endophytic bacterial diversity, the mechanisms involved in the nodule invasion and their effects on the hosts.","palabras_clave":"ENDOPHYTES|NODULE ENDOPHYTES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196695,"idioma_id":5,"titulo":"Experiencias interculturales vida de los jóvenes: reflexiones sobre estudiar y trabajar en contextos migratorios","resumen":"Una pregunta recurrente en nuestro trabajo ha sido ¿cómo construyen los niños\/as y los jóvenes, con biografías atravesadas por la experiencia migratoria, nuevas tramas de relaciones en un contexto de fuerte interpelación nacional y desigualdad social? Pretendo traer al debate del Foro algunas reflexiones iniciales a partir del trabajo de campo en curso, que permitan pensar la especificidad delos procesos que viven las generaciones migrantes en distintos espacios y atraviesan a la juventud de sectores subalternos. Durante la última década abordé la discusión sobre interculturalidad y educación, vinculando las experiencias formativas dentro y fuera de la escuela de niños\/as y jóvenes migrantes latinoamericanos en contextos escolares del sur de la Ciudad de Buenos Aires. Más recientemente empecé a estudiar la relación entre educación y trabajo en el norte del área metropolitana de Buenos Aires, atendiendo a los procesos vividos por los jóvenes y sus tránsitos entre las escuelas y el mundo del trabajo. Se trata de la investigación sostenida en un barrio fuertemente asociado a Bolivia, por la confluencia de población identificada con el referente Bolivia, y el peso y  visibilidad de sus organizaciones.Larelación entre educación y trabajo ha sido un tema presente en lainvestigación educativa, particularmente en el estudio de lascondiciones diferenciales de acceso y retención escolar de jóvenesde sectores populares. En este trabajo me propongo retomar latemática, poniendo atención en los jóvenes bolivianos (o hijos deinmigrantes de Bolivia) residentes de un barrio del conurbanobonaerense, con fuerte presencia de organizaciones productivas yrecreativas nucleadas como colectividad. Problematizoel lugar de las generaciones en contextos migratorios, abordando elpeso que el desplazamiento vivido por las familias imprime sobre lasdefiniciones de los jóvenes y su participación en distintosespacios institucionales de prácticas. Abordo al mismo tiempo latensión entre desigualdades estructurales y diferenciassocioculturales, como nudo problemático de las relaciones escolares,laborales y comunitarias de la población.","palabras_clave":"INTERCULTURALIDAD |MIGRACIÓN|EDUCACIÓN Y TRABAJO|JUVENTUD"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196699,"idioma_id":4,"titulo":"Aquaporins-Aquaporins in fetal development","resumen":"AQPs are essential for the correct development of many organs like heart, skin, lung, central nervous system and so others.The regulation of placental water transfer and intramembranous resorption are poorly understood; however, both phenomena support the hypothesis thatAQP water channels may be fundamental to the regulation of fetal water flow. In addition, several disorders such as abortion, premature birth, amniotic fluid volume.Abnormality, malformation and fetal growth restrictions may result when the homeostasis of the maternal-fetal fluid exchange is disrupted.","palabras_clave":"AQUAPORINS|HUMAN PLACENTA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":196823,"idioma_id":5,"titulo":"La derecha nacionalista. Decepciones políticas e influjos culturales","resumen":"El recorrido de la tendencia que le puso nombre a la década del 30, es la historia de una voluntad  ideológica atemorizada y muy dinámica que instaló pautas culturales de amplio y extendido alcance, pero no logró traducirlas en posiciones políticas y de poder concretas. Su radicalización liberó del estigma derechista a otras corrientes y movimientos que aparecían como moderados, incluso democráticos, en términos comparativos. No alcanzó desarrollos teóricos profundos, aunque penetró los imaginarios sociales y políticos. Buena parte de sus manifestaciones más radicales fueron una apelación a los propios, casi como una contraseña identitaria surgida de los fracasos, una coraza aglutinante y protectora,  antes que un recurso  para interpelar o convocar a otros individuos o sectores sociales.","palabras_clave":"derecha|nacionalismo|década infame"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197022,"idioma_id":5,"titulo":"Mburucuyá o los artificios de la representación","resumen":"La figura de Alexander von Humboldt (1769-1859) es una de las más significativas de la cultura de Occidente, y su relevancia alcanza tanto a la historia de Europa como a la de América Latina, ya que, según Simón Bolívar, fue su descubridor científico. Numerosos ensayos e investigaciones desde la historia cultural y política, así como de la historia de la ciencia, se han ocupado de destacar el enorme aporte de Humboldt al conocimiento, poniendo el acento en su concepción holística e integradora de la naturaleza, que alcanzó con él una máxima formulación pero que no tendría continuidad merced a la compartimentación de las ciencias especializadas en el transcurso del s. XIX. Pero nuestro propósito no es sumar un homenaje más ni abordar algún aspecto de la vida y obra de Humboldt. Este texto habla de ?representaciones? y más específicamente del film Mburucuyá, cuadros de la naturaleza, que Jorge Luis Acha rodó en 1996 inspirándose en Viaje a las regiones equinocciales del Nuevo Continente, uno de los textos más difundidos de Humboldt. Acha propone en su película una versión del sabio y de su experiencia en Sudamérica que difiere notablemente de aquella, establecida en forma canónica, que lo instala como modelo de héroe científico. A la vez, como veremos, la película recoge ciertas constantes de las representaciones que han configurado el imaginario sobre América, aunque en una clave que permite ponerlas en cuestión.","palabras_clave":"MBUCURUCYA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197059,"idioma_id":5,"titulo":"Programa Pueblos Indígenas de la Universidad Nacional del Nordeste. Algunas reflexiones y propuestas en torno a la inclusión y la interculturalidad","resumen":"En un trabajo anterior hemos realizado una descripción general del Programa Pueblos Indígenas (PPI) que tiene lugar en la Universidad Nacional del Nordeste (UNNE) de Argentina, tomando en cuenta rasgos principales del mismo.En este capítulo nos interesa avanzar en la descripción y el análisis de dos aspectos centrales como son el ingreso y la permanencia de estudiantes indígenas, y las acciones implementadas recientemente en torno a desarrollar procesos de interculturalidad en la Universidad. En primer término hacemos una presentación somera del contexto étnico-político en el cual surge el PPI, y de datos estadísticos sobre la inclusión de los indígenas en el sistema educativo provincial. Posteriormente, realizamos una breve caracterización del Programa. A continuación, nos extendemos en los temas propuestos. En lo relativo al ingreso y la permanencia caracterizamos el total de becarios según pueblo y lugar de procedencia, género y carrera que cursan; tratamos el tema según las visiones de los estudiantes y de los miembros del PPI, y exponemos acciones emprendidas tendientes a apoyar la permanencia y logros recientes. En lo atinente a procesos de interculturalidad, narramos las acciones implementadas y reflexionamos sobre los sentidos implicados en la participación de integrantes de la Comisión Asesora en el diseño y el desarrollo de las mismas. Cerramos el capítulo dejando planteadas propuestas y desafíos con vistas a garantizar el ingreso, la permanencia y la graduación de indígenas, y el desarrollo de procesos de interculturalidad en las Universidades.","palabras_clave":"ESTUDIANTES INDIGENAS|AUTORIDADES TRADICIONALES|PARTICIPACIÒN|UNIVERSIDAD CONVENCIONAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197161,"idioma_id":4,"titulo":"Neuropsychiatric symptoms related to cholinergic deficits in Parkinson´s disease","resumen":"Given its ability to explain the most frequent motor symptoms of Parkinson disease (PD), degeneration of dopaminergic neurons has been considered one of the disease´s main pathophysiological features. Several studies have shown that neurodegeneration also affects noradrenergic, serotoninergic, cholinergic and other monoaminergic neuronal populations. In this work, the characteristic contribution of cholinergic deficits to cognitive dysfunction, psychosis and sleep disturbances in PD and their treatment will be explored. Important neurophysiological processes at the root of several motor and cognitive functions remit to cholinergic neurotransmission at the synaptic pathway and circuital levels. The bulk of evidence highlights the link between cholinergic alterations and the aforementioned symptoms. The pathophysiology of these symptoms is related to degeneration of cholinergic nuclei, most importantly the nucleus basalis magnocellularis and the pedunculo-pontine nucleus. Rivastigmine, a drug that increases cholinergic tone by inhibiting the enzyme cholinesterase, is effective for dementia, whereas the use of Donepezil is still in the realm of investigation.Evidence on the clinical effects of these drugs for psychosis and REM-sleepdisturbances is still weak. Anticholinergic drugs should be used with caution in PD, as they may aggravate these cholinergic symptoms.","palabras_clave":"PARKINSON'S DISEASE|ACETYLCHOLINE|NEURODEGENERATION|TREATMENT|PATHOPHYSIOLOGY"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197361,"idioma_id":4,"titulo":"Political representation and malaise in representation in present-day Argentina","resumen":"Para comprender las tensiones en la representación política en la Argentina reciente, se analizan dos dimensiones de la relación entre ciudadanos y políticos vinculadas con el juego electoral, el proceso institucional y la movilización social. Primero, el devenir del vínculo de los ciudadanos con los partidos y con los gobiernos en relación a algunos clivajes políticos y culturales ?en especial la oposición entre peronismo y no peronismo? que especifican la distancia de los primeros con los segundos. Segundo la constitución a lo largo del actual ciclo democrático de formas de participación en tensión con la mediación partidaria y de gobierno que sirvieron tanto para definir los marcos del descontento político como de canales de expresión de esas demandas no representadas por la política institucional.","palabras_clave":"REPRESENTATION|PARTIES|DEMOCRACY|ARGENTINA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197454,"idioma_id":5,"titulo":"Mapeo de Rocas Metamórficas","resumen":"El metamorfismo es un proceso geológico endógeno que produce cambios en la mineralogía, estructura y composición química de rocas preexistentes y conduce a la formación de rocas metamórficas. En la litósfera, es el resultado de una perturbación térmica que puede o no estar acompañado por deformación y si no se manifiesta tal perturbación, no se produce metamorfismo, y la tectónica por sí misma, sólo produce estructuras de deformación sin cambios mineralógicos sustanciales. Según el tipo de metamorfismo, los agentes físicos y químicos actuantes, los protolitos involucrados y el ambiente geotectónico, los terrenos ígneo-metamórficos tienen rocas y estructuras diagnósticas que se representan en los mapas geológicos como masas rocosas independientes, formando distintas unidades cartográficas.En este capítulo se explican distintas técnicas de mapeo de las rocas metamórficas, que son de uso corriente en el campo. Se complementan con caracterizaciones concisas de las rocas y de sus protolitos, de los minerales, texturas y fábricas producidas por metamorfismo regional y local. El capítulo está ilustrado con ejemplos de rocas metamórficas de los terrenos de basamento más difundidos de Argentina, tanto en los afloramientos como en muestras de mano, y aún en láminas delgadas bajo el microscopio petrográfico.","palabras_clave":"CARTOGRAFIA|METAMORFISMO|GEOLOGIA|PETROLOGIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197637,"idioma_id":5,"titulo":"Morfología postcraneana de las poblaciones humanas neuquinas del Holoceno tardío","resumen":"En este trabajo se evalúa el cambio en la morfología delesqueleto postcraneano entre dos grupos humanos de diferentes antigüedades(4500 a 3500 y 2000 a 200 años). Las muestras se diferencian en la presencia decerámica, interpretada como un cambio tecnológico vinculado al modo dealimentación. Las comparaciones se hicieron a partir de análisis multivariados (MANOVAy PERMANOVA y componentes principales) y univariados (ANOVA y Kruskal- Wallis).Los resultados son consistentes en mostrar que la muestra tardía presentadiáfisis de mayores dimensiones que la temprana, mientras que el resto de lasmedidas no presenta diferencias (a excepción del extremo distal del fémur). Lasdiferencias halladas podrían estar relacionadas con fenómenos de plasticidadfenotípica como consecuencia de cambios en los patrones de actividad. Laevidencia isotópica, en coincidencia con los resultados de este trabajo, permitedescartar que cambios en la dieta hayan actuado en la diferenciación de laspoblaciones. El efecto del clima se observa en escalas geográficas y temporalesmayores a las inherentes a este estudio.","palabras_clave":"POSTCRÁNEO|POBLACIONES HUMANAS|HOLOCENO TARDÍO|NOROESTE DE PATAGONIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197779,"idioma_id":4,"titulo":"StAR","resumen":"For many years now, several studies in steroid-producing systems have led to the postulation of an induced stimulatory protein originally designated as the labile protein factor since after stimulation with ACTH in the presence of a protein synthesis inhibitor as cycloheximide (CHX), the rate of steroidogenesis rapidly returned to its unstimulated level (Haynes et al. 1959; Garren et al. 1965; Schulster et al. 1970). Using two-dimension gel electrophoresis, one of the first papers in the matter identified a protein of 28,000 Da, present as different isoforms in hormone-stimulated adrenal cells but not in quiescent cells. Furthermore, 35S-methionine pulsechase experiments showed that this protein is not produced from a preexisting one, even if protein synthesis is not inhibited (Krueger and Orme-Johnson 1983).","palabras_clave":"StAR|PHOSPHOPROTEIN|HORMONE REGULATION|MAMMALIAN TISSUES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197834,"idioma_id":5,"titulo":"Mapas de Riesgo de Enfermedades Transmitidas por Mosquitos","resumen":"Los mapas de riesgo de enfermedades trasmitidas pormosquitos buscan caracterizar la heterogeneidad espacial de la probabilidad detransmisión de una enfermedad o infección. Suelen usar información temporal yespacial, y pueden basarse en la asociación de casos a variables del entorno(modelos estadísticos) o en modelos matemáticos que simulan los pasos de latransmisión (modelos mecanísticos). Entre los modelos que estiman el riesgo a escalaglobal o continental incluyendo a la Argentina, hay disponibles mapas sobredengue, malaria y dirofilariasis. A escala nacional, existen mapas de riesgo dedengue, malaria, dirofilariasis, chikungunya, y encefalitis de Saint Louis.Para algunas de estas enfermedades existen también pronósticos ante distintosescenarios de cambio climático.","palabras_clave":"MAPAS DE RIESGO|DENGUE|DIROFILARIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197838,"idioma_id":5,"titulo":"El enfoque CTS en carreras de Ingeniería.  Pertinencia y perspectivas.","resumen":"El presente trabajo surge como fruto de una  trayectoria de investigación en lo que hace a la formación de Ingenieros con contenidos de los estudios sociales de la ciencia y la tecnología (CTS).La formación de Ingenieros en la actualidad requiere de un amplio marco conceptual que permita dar cuenta de la complejidad de las relaciones sociales que responden a los patrones del desarrollo de la ciencia y la tecnología en una forma, muchas veces, mas acelerada  de la capacidad misma de comprensión.  En este sentido, observamos que existe una controversia respecto a formar ingenieros con visión instrumental o integral.  Estas posturas conviven en las instituciones, ya sean organizaciones profesionales o instituciones universitarias, a veces de manera implícita, explícita, por acción u omisión en la clasificación de bloques temáticos y la asignación de contenidos o cargas horarias. Los estudios sociales de la ciencia y la tecnología, en adelante CTS, brindan un marco teórico adecuado para la formación integral de ciudadanos en general y profesionales de diversos campos en particular, sobre todo de ingenieros.Debido a la falta de sincronicidad entre los avances del conocimiento científico tecnológico y los cambios en los diseños curriculares de las carreras de Ingeniería, nos encontramos frente a un déficit en cuanto a la incorporación plena de estos contenidos, que, en algunos casos excepcionales se viene haciendo desde el esfuerzo de unos pocos docentes en asignaturas aisladas.  Nos proponemos dar cuenta de la complejidad que reviste el currículo en sí mismo, analizándolo como un dispositivo que responde a las condiciones de contexto y que, en algunas ocasiones, funciona con características diferentes a las premisas de sus enunciados.  Al mismo tiempo presentaremos características del enfoque CTS en general y las propuestas de inclusión de estos contenidos sugeridas desde el propio campo disciplinar.Finalmente describiremos cómo se abordan, o no, estos contenidos en algunas Universidades de nuestro país y daremos recomendaciones para la inclusión de contenidos CTS en carreras de Ingeniería, a tener en cuenta en los nuevos diseños curriculares de carreras de Ingeniería que se encuentran en proceso de elaboración en la actualidad.","palabras_clave":"TECNOLOGIA|FILOSOFIA DE LA TECNOLOGIA|INGENIERIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197849,"idioma_id":4,"titulo":"The crater lake of Copahue volcano (Argentina): geochemical and thermal changes between 1995 and 2015","resumen":"The crater lake and associated hydrothermal features of Copahue volcano have been&lt;br \/&gt;studied intensively over the last 20 years (1995?2015). The geochemical and isotopic compositions&lt;br \/&gt;of the waters provide insights into the processes occurring in the volcanic?hydrothermal system,&lt;br \/&gt;the crater lake and the thermal springs. Variations in the temperature and chemical&lt;br \/&gt;composition of the waters reveal fundamental changes in the system that precede and accompany&lt;br \/&gt;the magmatic and phreatic eruptive events at Copahue. A conceptual model of the summit system&lt;br \/&gt;was developed involving the intrusion of slivers of magma in the hot acidic hydrothermal cell, the&lt;br \/&gt;saturation of waters with secondary minerals leading to reduced permeability, the blocking of fluid&lt;br \/&gt;pathways by liquid sulphur during heating events and the transport of gas from the magma through&lt;br \/&gt;the ductile?brittle transition into the hydrothermal system. Geophysical data were integrated with&lt;br \/&gt;the chemical data to provide new insights into the behaviour of the deep magmatic system that&lt;br \/&gt;feeds the volcano edifice. Multidisciplinary studies were used to identify precursory signals of&lt;br \/&gt;eruptive activity to give an early warning of pending volcanic hazards. Several geochemical ratios&lt;br \/&gt;in river water were identified as potential indicators of upcoming volcanic activity, which could be&lt;br \/&gt;used in co-operation with the community and local authorities to deal with these volcanic hazards.","palabras_clave":"CRATER|LAKE|COPAHUE|GEOCHEMISTRY"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197909,"idioma_id":5,"titulo":"El siglo V y los bárbaros. Una aproximación a las transformaciones militares y sociales en la Antigüedad tardía","resumen":"El presente trabajo intenta realizar una aproximación a algunos de los cambios socio-culturales que tuvieron lugar en el imperio romano tardío, más precisamente, durante el siglo V. Para llevar a cabo esta tarea, el eje de la ponencia estará representado por las transformaciones que se produjeron en el seno de las aristocracias galo romanas, como así también dentro del ejército, institución en la que el elemento ?bárbaro? desempeñó un papel sin igual en el siglo V. Haremos hincapié, además, en las relaciones entre bárbaros y romanos durante este período, las cuales, consideramos, tampoco estuvieron exentas de cambios.","palabras_clave":"BÁRBAROS|ROMANOS|EJÉRCITO |TRANSFORMACIÓN"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":197923,"idioma_id":4,"titulo":"MITOCHONDRIAL BIOENERGETICS DURING ISCHEMIA AND REPERFUSION","resumen":"During recent years many works have described the morphological interactionbetween mitochondria and sarcoplasmic reticulum (SR) with different methodologies,such as co-localization with Ca2+ fluorofores and confocal microscopy in cardiomyocytesor detecting electron-dense bridges between the terminal cisternae ofthe SR and mitochondria by transmission electron microscopy which remain stillduring the isolatio. Nevertheless, these models are far from the pathophysiologicalsituation of ischemia\/reperfusion (I\/R) and they do not provide a good estimationof the functional interaction between mitochondria and SR. Alternatively,the mechano-calorimetrical approach provides a tool to study this interaction inwhole hearts exposed to no-flow ischemia and reperfusion, by means of selectivepharmacological tools.alorimetry was first used to estimate cardiac energetic of beating and restingstate in papillary muscles from different species [5, 6] and then in entire perfusedhearts [7]. The heat fractions associated to the Ca2+ activation (binding to troponin-Cand ATP hydrolysis for cytosolic removal), to the actomyosin ATP-cycling and to themetabolic recovery of ATP levels were recognized by the different methodologies [6,8?11]. The flow calorimeter provided a tool to understand Ca2+ movements [7, 12?14]. The thermopiles were used with papillary muscles under hyperthyroid state tostudy cardiac heat fractions under this pathological influence [15] and in senility[16]. More recently, a new work-loop microcalorimeter is being used with trabeculaefrom diabetic rabbits to study the influence of this pathology on the efficiencyafterloadrelationship [17, 18]. Nevertheless, only the flow calorimeter for entireperfused hearts is able to measure heat rate under no-flow or low-flow ischemia, asmodels to study the consequences of ischemia\/reperfusion in entire hearts [19?26].Mitochondria release an important fraction of the total heat flow, both in restingand during steady-state beating, because they provide metabolism and resynthesisof the ATP continuously consumed by ionic pumps and myofilaments. But part ofthe mitochondrial heat output is related to the maintaining of their own electrochemicalgradient (&#916;&#936;m) and Ca2+ transport. The control of mitochondrial calciumconcentration ([Ca2+]m) is a key to regulate the activity of some enzymes of thetricarboxylic acid cycle (TCA) and adjust metabolism and ATP synthesis to thecardiac cytosolic demand [16, 27]. The [Ca2+]m mainly depends on the uptake bythe uniporter (UCam) driven by the &#916;&#936;m and the extrusion by the mitochondrialNa+\/Ca2+ exchanger (mNCX), in a balance which finally determines that [Ca2+]moscillates in beat-to-beat transients. There are species-dependent differences in the level of free mitochondrial Ca2+, which have been attributed to thecytosolic [Na+], since this ion is the main driver of mitochondrial Ca2+ extrusion via the mNCX. Maack and colleagues demonstrated that inhibition of UCam with Ru360 in guinea-pig myocytes reduced the mitochondrial Ca2+-transients but symmetrically increased the cytosolic Ca2+-transients measured respectively by confocal microscopy with the fluorofores Rhod-2 and Indo-1 in a patch-pipette. In addition, the inhibition of mNCX with CGP-37157 produced the opposite changes . Considering the interaction between mitochondria and SR, it was shown that Ca2+ released by the RyR2 at about 100 &#956;M is able to induce the UCam uptake with the consequent increase in [Ca2+]m. Also, physiologically induced mitochondrial reactive oxygen species (ROS) can regulate the SR release by RyR2.Thus, Ca2+ and ROS participate in the functional interaction as parts of a fine and adjusted control of energetic balance between metabolism and ATP consumption","palabras_clave":"CALORIMETRY     |HEART|MITOCHONDRIA|SARCOPLASMIC RETICULUM|ISCHEMIA-REPERFUSION|CALCIUM|THYROID HORMONES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198035,"idioma_id":5,"titulo":"La figura del líder en el nacionalismo de derecha argentino. Un recorrido por las representaciones acerca del liderazgo político en los escritos de Marcelo Sánchez Sorondo","resumen":"Frente a las preguntas acerca de las razones que motivan a los sujetos a entablar relaciones de obediencia y su influencia en el surgimiento de contextos autoritarios, considero que observar este vínculo en los nacionalistas argentinos es muy fructífero, debido a la importancia de esta corriente en la cultura política y en la sociedad argentina en general de gran parte del siglo XX (1930-1980); período en el que, por otra parte, prevalecieron los regímenes autoritarios.Con esta idea en mente, consideré que volver sobre los rastros de las representaciones del líder ideal en la obra de un intelectual nacionalista representativo de su grupo y de su tiempo, como lo fue Sánchez Sorondo, habría de resultar esclarecedor. Así, desde esta perspectiva, el relato de Sánchez Sorondo acerca de los vínculos del nacionalismo con los presidentes argentinos mencionados a lo largo de este trabajo sirvió como excusa para observar la dinámica de la relación entre el tipo ideal de líder nacionalista y sus seguidores, según se plasmó en el discurso nacionalista.","palabras_clave":"LIDERAZGO POLITICO|SIGLO XX|NACIONALISMO|BIOGRAFIA INTELECTUAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198056,"idioma_id":2,"titulo":"Schmerz und Angst in Migräneanfällen:  metaphorische Konzeptualisierung und Formulierungs¬mittel in Erzählungen von Patienten","resumen":"In diesem Beitraganalisiere ich mehrere Erzählungen von kritischen Situationen, die von Migränepatienten durchlebt wurden. Erzählungen über Krankheit sind Gegenstand steigenden Interesses verschiedener Disziplinen. Medizinsoziologie, Psychologie, Anthropologie und Diskursanalyse bzw. Gesprächsanalyse erkannten schon seit einigen Jahrzehnten die Bedeutung kommunikativer und interaktionaler Aspekte im Feld des Gesundheitswesens (z.B. Atkinson 1995; Atkinson et al. 2001, unter vielen anderen). Später sind auch innerhalb der Medizin Strömungen entstanden, die das Erzählen über die Krankheit in den Vordergrund stellen (Charon, 2006). Im Laufe der letzten Jahrzehnte hat die starke gesellschaftlicheNachfrage die Notwendigkeit verdeutlicht, die Erfahrungen der Patienten und ihre Erzählungen ernst zu nehmen. Dies hatzu verschiedenen Initiativen im Gesundheitsbereich geführt, welche die medizinische Ausbildung hinsichtlich kommunikativer Aspekte verbessern soll. Es geht insbesondere darum, dafür zu sensibilisieren, dass das Wort der Patienten für die Diagnostik und die Behandlung eine ganz besondere Bedeutung hat. So hat die Stimme der Patienten in den letzten Jahren ein neues Gewicht erlangt, nachdem sie im Gesundheitswesen jahrelang nicht beachtet wurde.Wie verschiedene Forschungen über Herzkrankheiten und Anfallserkrankungen gezeigt haben, können sprachwissenschaftliche Untersuchungen einen Beitrag zur Kenntnis und zum Ver¬ständnis von Krankheit leisten, ebenso wie zur Diagnostik und Therapie (vgl. dazu unter anderem Gülich\/Schöndienst 1999; Schwabe et al. 2008; Schwabe et al. 2007).Dieser Beitrag ist Teil eines noch laufenden umfangreicheren Forschungsprojekts . Auf der Grund¬lage der Metapherntheorie und der Theorie der Textproduktion präsentiere ich hier eine Korpusanalyse von Patientenerzählungen, in welchen die Patienten ihre Migräneanfälle gegen¬über Freunden und Familienangehörigen erläutern. Mich interessiert es, dabei die genauen Prozeduren herauszuarbeiten, mit der die Patienten ihre Krankheit konzeptualisieren, insbesondere ihr hauptsächliches Symptom, die Kopfschmerzen.","palabras_clave":"metáforas y dolor|reformulación|producción de discurso|oralidad"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198057,"idioma_id":5,"titulo":"Los textos de la ciencia: Revisión crítica y prospectiva","resumen":"Desde el punto de vista teórico, este trabajo tiene como marco la perspectiva general de la lingüística del texto y desarrollos derivados de esa orientación,  con una impronta fuerte de la tradición alemana. El trabajo se propone, en primer lugar, presentar un conjunto de antecedentes sobre cuestiones epistemológicas que han determinado la investigación de  los textos científicos, esencialmente: qué tensiones han caracterizado la debatida relación entre lenguaje y ciencia; cómo han sido caracterizados tradicionalmente los textos científicos y cuáles de sus modalidades y aspectos se han privilegiado. En segundo lugar, se ofrece una posible definición de los textos científicos, basada en los enfoques multidimensionales de la lingüística textual, para, en una última sección, analizar de manera ejemplar un fragmento oral. Esta ilustración tiene por propósito abogar por una intensificación de las investigaciones sobre el discurso oral en este ámbito.","palabras_clave":"Discurso científico|Textos especializados"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198180,"idioma_id":5,"titulo":"Fitolitos","resumen":"No corresponde","palabras_clave":"Biomineralizaciones|Silicofitolitos|Calcifitolitos|Latinoamerica"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198213,"idioma_id":5,"titulo":"Las sociedades indígenas del Tucumán colonial. Una breve historia en larga duración. Siglos XVI-XIX","resumen":"Este trabajo intenta realizar una apretada síntesis de esa compleja historia poniendo énfasis en dos elementos centrales del proceso de dominación colonial: las formas de tributación y los procesos de reducción de la población sometida junto con las posibilidades de acceso a tierras y recursos propios. La misma abarca desde los procesos de conquista en las diferentes regiones hasta los procesos de desamortización de las tierras indígenas comunales a principio del Siglo XIX.","palabras_clave":"sociedad indigena|colonial|tierras|Tributos"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198241,"idioma_id":4,"titulo":"State and transition models: Theory, applications, and challenges","resumen":"State and transition models (STMs) are used for communicating about ecosystem change in rangelands and other ecosystems, especially the implications for management. The fundamental premise that rangelands can exhibit multiple states is now widely accepted. The current application of STMs for management, however, has been limited by both the science and the ability of institutions to develop and use STMs. In this chapter, we provide a comprehensive and contemporary overview of STM concepts and applications at a global level. We first review in detail the ecological concepts underlying STMs with the goal of bridging STMs to the recent theoretical developments and debates in ecology. We then provide a synthesis of the history of STM development and current applications in rangelands of Australia, Argentina, the United States, and Mongolia, exploring why STMs have been limited in their application for management. Key challenges in the use of STMs for management are addressed and recent advances that may improve STMs, including participatory approaches in model development, the use of STMs within a structured decision-making process, and mapping of ecological states are described. We conclude a summary of actions that could increase the utility of STMs for collaborative adaptive management in the face of global change.Ver: https:\/\/www.ars.usda.gov\/research\/publications\/publication\/?seqNo115=321760","palabras_clave":"ECOLOGIA|MANEJO|RESILIENCIA|SUSTENTABILIDAD"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198269,"idioma_id":5,"titulo":"Tic y lenguas extranjeras en la universidad: un camino hacia la enseñanza","resumen":"La incorporación de las Tecnologías de la Comunicación y Comunicación (TIC) a los procesos educativos dio lugar a la emergencia de la Bimodalidad, un proceso que significa un cambio paradigmatico en la formación. En esencia, proporciona un equilibrio entre la flexibilidad e interactividad signada por la tecnología.","palabras_clave":"UNIVERSIDAD|LENGUAS EXTRANJERAS|TIC|COMPLEMENTACIÓN"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198285,"idioma_id":5,"titulo":"Poder y conflicto. Constitución de actores, entramado social y consolidación del territorio","resumen":"El poder es una relación social que delimita y potencia los vínculos intersubjetivos a través de prácticas que se caracterizan por su dinamismo y su asimetría. Es una capacidad, que no tiene por qué ejercerse, que lo convierte en el medio que permite administrar el conflicto social o, como contrapartida, eliminarlo. El carácter vinculante del poder permite entonces relacionar a distintos actores, con diversas capacidades para actuar y transformar el entramado social. Se destaca el reconocimiento de la diversidad como una característica fundacional del poder, que se combina con la simultánea consolidación de las estructuras institucionales y la constitución de los sujetos en ciudadanos.El conflicto como expresión de esta diversidad de actores también es parte de los vínculos de poder. El saber ocupa entonces un rol fundamental que permite reconocer la heterogeneidad de los sujetos con capacidad de resistencia y destaca la interdependencia que caracteriza al entramado social. Actores, instituciones, reflexiones y conocimientos se delinean a través de la dependencia que el poder tiene con el saber. Siempre es necesario un conocimiento, sistemático o no, para que existan los vínculos de poder pero también para que se produzcan las interacciones sociales. Así, los sujetos se constituyen en actores, se consolidan las instituciones y se socializan los aspectos territoriales y medioambientales en donde se insertan y contienen estos vínculos.EL ISBN CONSIGNADO ES A TITULO INFORMATIVO. VER CERTIFICADO ADJUNTO","palabras_clave":"TERRITORIO|ACTORES SOCIALES|PODER|CONFLICTO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198286,"idioma_id":5,"titulo":"Territorio y poder en el mundo rural. Alcances de una interdependencia social en el siglo XX","resumen":"El poder potencia la complejización del entramado social que demanda un sistema productivo que promueve la transformación de los espacios geográficos. El mundo rural es parte de estos cambios territoriales con implicancias socio-económicas y culturales, en los cuales el vínculo saber-poder impulsa la subjetivación y el carácter social del territorio.  A partir de la interdependencia saber-poder que fundamenta la perspectiva foucaultiana de la gubernamentalidad, el objetivo es conceptualizar al territorio desde la sociología focalizando en el carácter mediador del poder dentro de los vínculos sociales. Al trascender la politización del biopoder acuñada por Michel Foucault, se propone ponderar las implicancias fundacionales de las interacciones sociales en el territorio. Un entramado conceptual que permite reconstruir un recorrido histórico general del ámbito rural pampeano, desde finales la ?Argentina criolla? del siglo XIX hasta la ?Argentina sojera del agronegocio? que se fundamenta en  las transformaciones que introducen los organismos genéticamente modificados (OGM) a finales del siglo XX.La consolidación agropecuaria de la Argentina Moderna del siglo XIX, el fin de la expansión horizontal agraria para mediados de la primera década del siglo XX, las distintas prácticas intervencionistas del período 1930-1955, la revolución verde de la década de 1960, la escisión del sujeto agrario para los años 70 y las lógicas del agronegocio comparten una interpelación del territorio a partir de una interpretación compleja capaz de reflejar los vínculos de poder imperantes. Al trascender la lógica natural y social del espacio geográfico es posible ponderar su capacidad explicativa de la heterogeneidad territorial del agro pampeano.EL ISBN CONSIGNADO ES A TITULO INFORMATIVO. VER CERTIFICADO ADJUNTO","palabras_clave":"AGRO|TERRITORIO|PODER|SIGLO XX"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198301,"idioma_id":5,"titulo":"Buenaventura González Peronismo, sindicalismo y política en la localidad","resumen":"Entrevista a Buenaventura González, secretario general del sindicato Empleados de Comercio durante el primer peronismo en Mar del Plata. Edición.","palabras_clave":"PERONISMO|ENTREVISTAS|SINDICALISMO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198302,"idioma_id":5,"titulo":"Rogelio García Lupo Periodismo, peronismo y nacionalismo","resumen":"Entrevista a Rogelio García Lupo , reconocido periodista argentino, acerca de sus actividades durante el primer peronismo y en los años posteriores a la 'Revolución Libertadora. Edición.","palabras_clave":"PERONISMO|MEDIOS DE COMUNICACIÓN|ENTREVISTA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198304,"idioma_id":4,"titulo":"Approaches for in vitro conservation of woody plants germplasm.","resumen":"The conservation of plant genetic diversity aims at preserving as much as possible extant species by using innovative and complementary approaches to guarantee the effec-tiveness of the safeguarding strategies and to face present problems and future threats. The development and implementation of different in vitro conservation techniques have provided improvements for the international exchange of germplasm, for the storage of different in vi-tro culture forms and for products generated by biotechnology. These methods are also a valuable alternative to relieve the need of large lands extensions, where reserve collections of trees belonging to many woody species are traditionally kept. This chapter provides in-formation of several study cases, describes some useful protocols, and aims at presenting a brief overview of currently available techniques for in vitro conservation to medium and long-term of woody plant germplasm.","palabras_clave":"WOODY PLANTS|SLOW GROWTH|CRYOPRESERVATION|BIODIVERSITY CONSERVATION"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198305,"idioma_id":5,"titulo":"Características biológicas y germinativas de Ludwigia bonariensis (Micheli) Hara (Onagraceae), una maleza importante en el cultivo del arroz.","resumen":"Ludwigia bonariensis (Micheli) Hara (Onagraceae) es una especie nativa de Sudamérica que crece en terrenos inundados, por lo que se la puede encontrar creciendo asociada al cultivo del arroz u otros cultivos e invadiendo cuerpos de agua. Es una especie alógama, produciendo 1.279 ± 251 semillas por cápsula. La germinación de las semillas es usualmente muy alta y se produce únicamente en condiciones de luz (fotoblastismo positivo), sin presentar disminución en su poder germinativo al menos al cabo de un año de almacenamiento a temperatura ambiente. Otra forma de propagación de esta especie es la vía asexual, por tallos subterráneos, lo que favorece su persistencia y brotación de una temporada a la siguiente. La germinación de las semillas se da en superficie en porcentajes entre 90 ± 3 y 95 ± 6 %, disminuyendo el poder germinativo a valores entre 37 ± 11 y 60 ± 9 % a una profundidad de siembra de 1 mm de suelo y a partir de una profundidad de 5 mm no se registra germinación. La inundación no sería una herramienta válida para el manejo de esta maleza ya que láminas de agua de 1 a 4 cm no afectan significativamente la germinación; sólo la presencia de una lámina de agua de 8 cm disminuye el poder germinativo de las semillas, aunque de todos modos la germinación se produce en alto porcentaje (~70%). Considerando la estrategia reproductiva de esta especie, los métodos de control mediante labranzas (enterrando las semillas) y\/o aplicación de herbicidas hormonales serían efectivos en etapas tempranas del establecimiento, contribuyendo a disminuir las poblaciones de plantas al estado adulto.","palabras_clave":"ESTRATEGIA REPRODUCTIVA|ALOGAMIA|FOTOBLASTISMO POSITIVO|RIEGO POR INUNDACIÓN"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198327,"idioma_id":5,"titulo":"Reflexiones sobre educación universitaria en Economía Social y Solidaria. Apuntes para el debate desde una práctica de democratización universitaria","resumen":"El presente trabajo plantea algunas reflexiones para el debate sobre lasvinculaciones entre universidades públicas y economía social y solidaria(ESS) en Argentina, con énfasis particular sobre las estrategias universitariasde formación de actores del sector. Dichas reflexiones se realizandesde una impronta de democratización de la educación superior, y surgendesde una práctica académica integral de docencia, investigación y extensiónuniversitaria en la temática que ya tiene una década","palabras_clave":"Economia social y solidaria|Democratizacion universitaria"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198339,"idioma_id":4,"titulo":"PROTECTIVE AND SYNERGISTIC EFFECTS IN THE RHIZOSPHERE, ARBUSCULAR MYCORRHIZAL FUNGI  AND BENEFICIAL BACTERIA","resumen":"Since the discovery of arbuscular mycorrhizal (AM) fungi, their morphology and beneficial behavior towards the host plant have been profusely investigated. Nowadays, it is also known that microorganisms as bacteria live intimately associated with AM structures. This leads to new studies in the field of sustainable agriculture, about their combination and the beneficial effect on the host plant.AM fungi exhibitfavorable effects on their host plant growth and development. However, AM inoculation is not only dependent on the plant-fungus combination but also on the soil conditions and the physiological state of the plant. These variables joined to the presence of associated bacteria, potentially alter the direct and indirect benefits of the AM symbiosis in the host plant improvement.In vitro assays studying the combined effects of those microorganisms showed impressive results which are buffered under greenhouse and field conditions. Therefore, it is very important to complement the laboratory and greenhouse work with field conditions, and even through working together with agricultural farmers to achieve optimal results. Taking into account the increasing interest for the reduction of the input of chemical fertilizers and the use of combined microorganisms as biofertilizers, particularly applied in organic agriculture, in this chapter we review our own studies on the impact of these rhizospheric microorganisms on plant host physiology and development.","palabras_clave":"arbuscular mycorrhizal fungi|associated bacteria|synergism|rhizosphere"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198385,"idioma_id":5,"titulo":"Nuevas disputas por el Derecho a la Comunicación en Argentina: el giro a la derecha a partir de diciembre de 2015","resumen":"Las políticas de comunicación y cultura que implementó el nuevo gobiernoargentino tras asumir en diciembre de 2015, representaron un cambio radical respecto de laregulación vigente hasta entonces y abarcaron al sector audiovisual, los servicios detelecomunicaciones, algunos espacios públicos de cultura y los medios y señales públicas.Por la vía de los decretos -algunos de ellos de necesidad y urgencia- el PENtransformó la arquitectura institucional creada por las anteriores normativas del Audiovisual y las Telecomunicaciones realizando modificaciones en sus áreas medulares y disolviendo las autoridades en ejercicio cuyos mandatos no había concluido. En paralelo, se aplicaron numerosos cambios en el articulado de ambas leyes, en un movimiento de liberalización y re-regulación a favor de los actores dominantes de mercado.Junto a la promesa de una nueva y única Ley de Comunicaciones Convergentes, segeneraron acciones de repudio y reclamo desde un amplio arco sectorial en el marco de una escena incierta, especialmente para los actores no lucrativos y públicos.","palabras_clave":"DERECHO A LA COMUNICACIÓN|REGULACIÓN |MEDIOS |DEMOCRACIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198429,"idioma_id":4,"titulo":"Indigenous peoples and Higher Education","resumen":"Indigenous Peoples and Higher Education encompasses an increasingly important field of experiences associated with the struggles of indigenous peoples and human rights movements. It involves the institutional practices of universities and other institutions of higher education worldwide, as well as governmental and intergovernmental agencies, non-governmental organizations, private foundations, and sectors of various churches. Experiences in this field take place through a wide variety of institutional arrangements that involve the participation of community leaders, indigenous and non-indigenous students, educators, researchers, and university officers. These include affirmative action programs as well as special degree programs at conventional universities, alliances between universities and indigenous peoples´ organizations, state-established intercultural universities, and college and universities founded by indigenous peoples. The development of these experiences --their achievements, challenges, and conflicts-- constitute significant areas of research and conceptual debates in Anthropology, Education, and interdisciplinary studies, among others","palabras_clave":"Indigenous Peoples|Higher Education"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198466,"idioma_id":5,"titulo":"Memorias migrantes: las identidades migrantes y la construcción de memorias colectivas","resumen":"En este capítulonos proponemos analizar la construcción (retención y reproducción) de la memoria de distintosgrupos mi- grantes, juntoa la formación de identidades hegemónicas y subalternas que los resignifican en las sociedadesde acogida. En particular, examinamos los discursos y las prácticas que contribuyen a la construcción, re- tención y transmisión de experiencias y relatos migrantescompartidos (entre pares, intra- einter- generacionalmente). En base adiversos estu- dios de caso, analizamos cómo distintos colectivos migrantes experimen-tan procesos de identificación, relacionados con la construcción de las memoriascolectivas en los lugares de destino. Nuestro análisis privilegia la interrelación entreel modo en que los grupos migrantes resignifican ? o no- aquellas vivencias, saberes y recuerdosque forman parte de sus ex-periencias en el lugar de origen. Las mismas proveen de marcos para la acción en la sociedadde acogida en donde los diversos grupos migrantestrabajan, se alimentan, enferman, educan (entre otras prácticas) y cuyasinteracciones y experiencias cotidianas los impulsa a recordar, olvidar o silenciar contenidos específicos de sus memorias colectivas.","palabras_clave":"memorias|identidades|migrantes|fronteras"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198535,"idioma_id":5,"titulo":"Pensando la desigualdad urbana desde el trabajo callejero","resumen":"A partir de los trabajos de campo que vengo desarro-llando asi&#769; como de los debates en los diferentes equipos deinvestigacio&#769;n en los que participo, el capi&#769;tulo propone algu-nas li&#769;neas de indagacio&#769;n para el abordaje de los procesos detrabajo considerados informales en el espacio urbano. Paralos casos a los que me voy a referir, las formas de trabajo(como pra&#769;cticas culturales enmarcadas en experiencias declase) marcan maneras sociales de insercio&#769;n urbana y deconstitucio&#769;n de vidas dignas. En tanto la venta ambulante y el cirujeo suelen serabordados como formas de obtencio&#769;n de dinero y recursos,el capi&#769;tulo propone una visio&#769;n que va ma&#769;s alla&#769; de las visio-nes centradas en los procesos econo&#769;micos como un campoauto&#769;nomo. Las dos experiencias de campo me han permi-tido comprender el modo en que los procesos econo&#769;micosesta&#769;n territorializados o, para decirlo de forma ma&#769;s precisa,las pra&#769;cticas de obtencio&#769;n de dinero son inescindibles de laconstitucio&#769;n del territorio y esta se produce a partir de laapropiacio&#769;n del espacio fi&#769;sico (y sus constren&#771;imientos) asi&#769;como de las relaciones interpersonales que se construyenalrededor de aquel.El capi&#769;tulo esta&#769; dividido en tres grandes secciones. Enla primera de ellas, me focalizo en la dimensio&#769;n urbana dela desigualdad marcando la necesidad de pensar el espaciono so&#769;lo como el lugar donde ocurren cosas. Luego, buscocomplejizar los procesos de desigualdad a partir de pensarlas formas de ganarse la vida no so&#769;lo desde la adquisicio&#769;n debienes materiales o de la esfera de lo econo&#769;mico sino comomodos de vida que tienen diferentes niveles de aceptacio&#769;n yque, al mismo tiempo, tienen efectos objetivos sobre la vidade las personas. En funcio&#769;n de la desigualdad territorialconstruida socialmente y de la desigualdad que se generaa partir de los diferentes modos de ganarse la vida, en latercera seccio&#769;n doy cuenta de las relaciones personales quevendedores y cirujas generan y mantienen, y que les permiteacceder al espacio y a la reproduccio&#769;n social.","palabras_clave":"DESIGUALDAD URBANA|TRABAJO CALLEJERO|BUENOS AIRES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198536,"idioma_id":5,"titulo":"La relación lástima-limosna como una variación del intercambio. Mendigos urbanos y vendedores ambulantes de Buenos Aires (Argentina)","resumen":"&amp;amp;amp;amp;lt;!-- \/* Font Definitions *\/@font-face{font-family:Times;panose-1:2 0 5 0 0 0 0 0 0 0;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:3 0 0 0 1 0;}@font-face{font-family:'&amp;amp;amp;amp;#65325;&amp;amp;amp;amp;#65331; &amp;amp;amp;amp;#26126;&amp;amp;amp;amp;#26397;';mso-font-charset:78;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:1 134676480 16 0 131072 0;}@font-face{font-family:'&amp;amp;amp;amp;#65325;&amp;amp;amp;amp;#65331; &amp;amp;amp;amp;#26126;&amp;amp;amp;amp;#26397;';mso-font-charset:78;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:1 134676480 16 0 131072 0;}@font-face{font-family:Cambria;panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:-536870145 1073743103 0 0 415 0;}@font-face{font-family:ACaslonPro;panose-1:0 0 0 0 0 0 0 0 0 0;mso-font-alt:'Times New Roman';mso-font-charset:0;mso-generic-font-family:roman;mso-font-format:other;mso-font-pitch:auto;mso-font-signature:0 0 0 0 0 0;} \/* Style Definitions *\/p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-unhide:no;mso-style-qformat:yes;mso-style-parent:'';margin:0cm;margin-bottom:.0001pt;mso-pagination:widow-orphan;font-size:12.0pt;font-family:Cambria;mso-ascii-font-family:Cambria;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:'&amp;amp;amp;amp;#65325;&amp;amp;amp;amp;#65331; &amp;amp;amp;amp;#26126;&amp;amp;amp;amp;#26397;';mso-fareast-theme-font:minor-fareast;mso-hansi-font-family:Cambria;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:'Times New Roman';mso-bidi-theme-font:minor-bidi;mso-ansi-language:ES-TRAD;}.MsoChpDefault{mso-style-type:export-only;mso-default-props:yes;font-family:Cambria;mso-ascii-font-family:Cambria;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:'&amp;amp;amp;amp;#65325;&amp;amp;amp;amp;#65331; &amp;amp;amp;amp;#26126;&amp;amp;amp;amp;#26397;';mso-fareast-theme-font:minor-fareast;mso-hansi-font-family:Cambria;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:'Times New Roman';mso-bidi-theme-font:minor-bidi;mso-ansi-language:ES-TRAD;}@page WordSection1{size:595.0pt 842.0pt;margin:72.0pt 90.0pt 72.0pt 90.0pt;mso-header-margin:35.4pt;mso-footer-margin:35.4pt;mso-paper-source:0;}div.WordSection1{page:WordSection1;}--&amp;amp;amp;amp;gt;No cualquiera pide de cualquier forma. Los efectos de esepedir están enmarcados en una serie de relaciones e imaginarios sociales queconfiguran formas (sociales) no solo de pedir sino de relaciones amplias. Pedires una relación social. Si un actor dado no agencia signos de lástima, nadie ledonará. Este simple hecho indica que las donaciones imponen exigencias queresultan necesarias para que el acto se concrete, por lo cual donar esestablecer una relación bi direccional: un intercambio desigual de diferentesbienes. A partir de las investigaciones que venimos realizando con personas quepiden en trenes de la ciudad de Buenos Aires (que lidian con la asistenciaestatal por razones médicas en una ciudad del centro de la provincia de BuenosAires, que sufren alguna discapacidad y que se relacionan a partir de esta condiferentes instituciones sociales tanto locales como provinciales&nbsp;&nbsp;ynacionales), en este trabajo ahondaremos en una idea que continuamente aparecevinculada con esta problemática y que habilita un análisis particular sobre losdiscursos y prácticas de los actores en relación con el 'darlástima'. Nos referimos a que antes que pensar que el pedir es un hechopasivo, que la lástima se da, es necesario enmarcar los actos en los procesosdeconstrucción y circulación del dar. Estas relaciones no pueden comprenderse sinoen una vinculación entre dar (pedir), recibir y devolver.&lt;!-- \/* Font Definitions *\/ @font-face{font-family:'Cambria Math';panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:roman;mso-font-pitch:variable;mso-font-signature:-536870145 1107305727 0 0 415 0;} \/* Style Definitions *\/ p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-unhide:no;mso-style-qformat:yes;mso-style-parent:'';margin:0cm;margin-bottom:.0001pt;mso-pagination:widow-orphan;font-size:12.0pt;font-family:'Times New Roman',serif;mso-fareast-font-family:'Times New Roman';}.MsoChpDefault{mso-style-type:export-only;mso-default-props:yes;font-family:'Calibri',sans-serif;mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:Calibri;mso-fareast-theme-font:minor-latin;mso-hansi-font-family:Calibri;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:'Times New Roman';mso-bidi-theme-font:minor-bidi;mso-ansi-language:ES-TRAD;mso-fareast-language:EN-US;}@page WordSection1{size:612.0pt 792.0pt;margin:70.85pt 3.0cm 70.85pt 3.0cm;mso-header-margin:36.0pt;mso-footer-margin:36.0pt;mso-paper-source:0;}div.WordSection1{page:WordSection1;}--&gt;","palabras_clave":"PEDIR|MENDIGOS|VENTA AMBULANTE|LÁSTIMA|INTERCAMBIO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198559,"idioma_id":5,"titulo":"Bases para una gestión del patrimonio arqueológico de la provincia de Córdoba","resumen":"En este acápite se brindará información relacionada con los resultados logrados a través del trabajo de relevamiento geoespacial del patrimonio arqueológico mueble (colecciones) e inmueble provincial. De esta manera se demuestra como la sistematización de los datos referentes a los sitios arqueológicos en un sistema de información geográfica (SIG) ha permitido identificar la distribución departamental de los mismos, los lugares con mayor desarrollo de las investigaciones, la situación de riesgo actual de estos sitios en los distintos departamentos, para mencionar algunas posibilidades. Asimismo, gracias al uso de la herramienta SIG se ha podido modelar áreas de riesgo para el componente patrimonial y planificar su gestión y\/o uso para generar la debida protección legal.Además se presentará aquí una introducción a la problemática del inventariado de sitios arqueológicos en la provincia de Córdoba, revelando el contexto en el que surgen los resultados que se presentan y algunas ideas sobre el estado de la cuestión. En este sentido se brindan datos acerca de la metodología llevada a cabo en el laboratorio, que incluyó el diseño de la base de datos (definición de criterios y construcción), además del relevamiento bibliográfico acerca de la información referente al patrimonio arqueológico de Córdoba. La etapa desarrollada en campo, que contó con la contribución de los más diversos actores interesados en la conservación y gestión del bien no-renovable en cuestión y en donde se llevó a cabo el relevamiento in situ de los datos, también es tratada en el capitulo. Finalmente se realiza una valoración de la información recopilada (en aproximadamente tres años de investigación) en el SIG. Estos datos se presentan divididos por departamento, hecho que ha permitido indagar acerca de la distribución de los sitios arqueológicos en la provincia, la calidad de la información que se dispone para cada departamento (origen del dato), sus condiciones presentes (situación actual y nivel de intervención) y los riesgos de destrucción que sufre el patrimonio arqueológico de la provincia de Córdoba.","palabras_clave":"PATRIMONIO|ARQUEOLOGIA|GESTION|SIG"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198581,"idioma_id":5,"titulo":"Cuenca lechera caprina de Santiago del Estero: producción primaria e industrial y desarrollo de nuevos productos lácteos","resumen":"La Cuenca lechera caprina del área de riego del río Dulce, ubicada en los departamentos Robles, Banda, Capital sur y Silípica norte, y las empresas lácteas que producen quesos caprinos, han sido estudiadas por diversos autores desde diferentes perspectivas. En este caso se realiza un aporte en relación con las características de los tambos caprinos, que impactan en la calidadde la leche que producen. Los resultados alcanzados permiten identificar las particularidades de éstos tambos, en manos de productores rurales, determinar la composición fisicoquímica y microbiológica de la leche producida, observando además que las características de la producción primaria impactan en la producción industrial de quesos, generando una dinámica en la cadena láctea caprina. Por otra parte, se caracterizaron las industrias lácteas caprinas locales en cuanto a la disponibilidad de servicios, infraestructura y equipamiento que emplean, productos que se elaboran, rendimientos y los principales problemas que afrontan para mejorar su rentabilidad.Considerando que dichas empresas se han dirigido exclusivamente a la producción de quesos se ha trabajado en el desarrollo de nuevos productos y procesos, se han diseñado fermentos con cepas autóctonas, pertenecientes al CERELA, con propiedades tecnológicas, para obtener nuevos productos diferenciados por su calidad: queso untable y una bebida láctea a base de suero.","palabras_clave":"BACTERIAS LACTICAS|CULTIVOS AUTOCTONOS|QUESOS CAPRINOS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198663,"idioma_id":5,"titulo":"Panorama etnoecológico de la pequeña horticultura familiar en enclaves rurales y urbanos del  Centro-Norte de la Patagonia.","resumen":"El paisaje patagónico, pensado como una construcción cultural, es causa y efecto de la manipulación humana de todos sus componentes naturales (Reis et al. 2014). Dicha humanización dependen de la visión de las sociedades que lo habita, siendo en este caso un territorio en donde se han proyectado a lo largo del tiempo diferentes cosmovisiones sobre su paisaje (Ladio & Molares, 2014). Para citar un ejemplo paradigmático es el caso de la  manzana (Malus domestica) traída por los Jesuitas a la región desde Chile en su intento infortunado de evangelizar a las comunidades originarias. Los manzanos se asilvestraron rápidamente y se expandieron exitosamente al sudoeste de la provincia de Neuquén, llamándose la zona como ?Gobernación de las Manzanas? en dominios del líder indígena Saihueke (mediados siglo XIX). Hasta el día de hoy las comunidades Mapuches de la zona fabrican una  bebida de significancia cultural y ritual, conocida vulgarmente como ?chicha? (Ladio & Lozada, 2000) y los manzanos asilvestrados constituyen parte primordial de los paisajes valorados por estas comunidades como también son incluidos en sus huertos domésticos. Es decir que los avatares históricos que se imprimen en el paisaje están permanentemente interactuando con los sistemas hortícolas que hoy en este libro nos interesan.Los paisajes hortícolas en el Centro-Norte de la Patagonia (provincias de Neuquén, Río Negro y Chubut), son unos de los paisajes que tienen el mayor grado de procesos de domesticación. Siguiendo a (Blancas et al. 2010), nos referimos al hecho que en estos ámbitos se han puesto en acción un conjunto de intervenciones y transformaciones a nivel de especies y de sus genes, y también a nivel del paisaje,  con el fin de adecuar el espacio para satisfacer  necesidades materiales  y espirituales (principalmente ligadas a la alimentación y la salud).","palabras_clave":"huertos familiares|diversidad agrícola|historia agricola|patagonia"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198787,"idioma_id":5,"titulo":"El doble carácter de la sustentabilidad en las organizaciones asociativas: prácticas económicas, políticas, sociales y ambientales en cooperativas de recuperadores urbanos de la Ciudad de Buenos Aires, 2007-2013","resumen":"La problemática de la sustentabilidad, ha sido abordada de manera continua desde los primeros debates que se abrieron en torno a ella en los años 70´, tras los sucesivos cuestionamientos realizados al modelo de acumulación vigente. A lo largo de las últimas décadas la noción de sustentabilidad ha estado presente en el desarrollo de programas y políticas públicas así como de organismos multilaterales y ha sido objeto de convenciones y acuerdos internacionales. Ahora bien, la noción de sustentabilidad continúa siendo un campo en disputa y han sido remarcadas en sendas ocasiones las dificultades que existen al momento de generar un consenso acerca de su definición así como de indicadores que permitan dar cuenta de ésta.  Uno de los usos más convencionales del término refiere al explicitado en el informe Brutland (1987) en donde se remarcan al menos dos cuestiones: 1. la sustentabilidad refiere a las prácticas del hoy y su incidencia en las generaciones futuras y 2. la necesidad de articular las dimensiones ambientales, económicas, sociales y políticas en los procesos de desarrollo. A partir de allí la noción de sustentabilidad ha sido también incorporada a los objetivos organizacionales de grandes, pequeñas y medianas empresas abriéndose nuevos debates acerca de lo que implica la sustentabilidad en el contexto organizacional. En este marco, las organizaciones asociativas constituyen un campo específico, dado por las particularidades que caracterizan a este tipo de empresas. Este capítulo busca aportar a estos debates a partir del análisis de las cooperativas de cartoneros de la Ciudad de Buenos Aires, en tanto tipo asociativo particular. Estas organizaciones, tras más de una década de su conformación, han tenido un reposicionamiento y legitimación en el sistema de higiene urbana local, siendo actualmente licitarias del servicio de recolección de RSU secos en la Ciudad. De ahí que, en un contexto en el cual el despliegue de políticas ambientales tiene por eje la inclusión social de los recuperadores ?informales? de residuos a través de su cooperativización, resulta de importancia reflexionar acerca de las normas y prácticas que habilitan garantizar la sustentabilidad de estas organizaciones.&#8195;Para ello buscaré dar cuenta de cómo los actores asociados construyen cotidianamente sus organizaciones, las regulaciones que pesan sobre la actividad que las enmarca y cuáles son los vínculos que se generan en estos procesos y de ahí, cómo ello puede producir procesos de transformación o reproducción de determinadas prácticas que habilitan o limitan la sustentabilidad de estas experiencias. Desde esta mirada se propone que el análisis de las prácticas asociativas y su vinculación con la sustentabilidad organizacional debe tener presente de manera continua una doble dimensión: aquella que hace referencia a los requerimientos impuestos a las organizaciones ?desde afuera? y aquellas exigencias propias de los colectivos de trabajo para construir consensos y normas propias de funcionamiento, acordes con las disposiciones externas. Esta dinámica ?en permanente tensión- es entendida como una ?doble sustentabilidad?, externa e interna.  Al hablar de sustentabilidad externa me refiero a los requerimientos de adaptación y encuadramiento de las organizaciones en las disposiciones que ?desde afuera? de la organización, imponen límites al accionar y construyen al mismo tiempo posibilidades de acción. La utilización de la figura jurídica cooperativa, la articulación con una determinada política pública o bien la adaptación a ciertos requisitos del mercado pueden ser entendidas de esta manera. Por otra parte, con sustentabilidad interna, me refiero a las necesidades y requerimientos de la organización en términos de crear y consensuar normas y prácticas que permitan mantener unido al colectivo que la constituye. La creación de símbolos y espacios comunes, de una identidad compartida y de reglas colectivas forma parte de esta dimensión. Cabe remarcar que en sendas ocasiones las exigencias que vienen de ?adentro? y de ?afuera? de las organizaciones no siempre son compatibles y muchas veces son hasta contradictorias, por lo cual la sustentabilidad se encuentra siempre en un equilibrio precario, que requiere ser constantemente recreado al modificarse las condiciones externas e internas de cada experiencia asociativa. De ahí que la reflexión en torno a la producción y reproducción de las prácticas asociativas requiere adoptar una perspectiva dinámica, atenta a las transformaciones contextuales, pero que también permita dar cuenta de los cambios en las aspiraciones e imaginarios de los trabajadores asociados","palabras_clave":"SUSTENTABILIDAD|ASOCIATIVISMO|RECICLAJE|CARTONEROS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198793,"idioma_id":6,"titulo":"La science latinoaméricaine: tensions du passé et enjeux du présent","resumen":"    Dans la première partie, nous faisons un résumé schématique des aspects  et contraintes les plus importantes pour le troisième quart du XXe siècle, de  la science dans les pays de l´Amérique latine et l´institutionnalisation des  différents domaines des connaissances. Dans la deuxième partie, nous analysons  la transition la plus récente d´une phase de construction de l´infrastructure  pour les sciences dans le cadre d´une science mondialisée quie se manifeste d?une  manière spécifique.  Nous examinons ainsi les questions émergentes au cours des dernières années en  termes de tensions entre l´émergence d´une nouvelle division internationale du travail  scientifique vis-à-vis la perspective nationaliste (voire fondamentaliste) apparaissant  dans certains pays. Nous passerons en revue les changements profonds qui ont  subi l´évaluation du système de recherche et les implications pour l´activité  scientifique. On discute également la reconfiguration des domaines de la  science avec l´émergence de nouvelles questions telles que l´environnement et  la biodiversité, les connaissances associées aux nanosciences, les biotechnologies,  les neurosciences et les nouveaux matériaux, ainsi que la diffusion des TICs .  En fait, nous allons regarder la nouvelle compréhension de la dynamique de la technoscience  et nous concluons en soulignant certains défis à l´heure actuelle entre le  développement des connaissances et la dynamique et les besoins des sociétés de  la région.  ","palabras_clave":"Histoire des sciences|Amérique Latine|Disciplines|Institutions"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198888,"idioma_id":4,"titulo":"Photon Transport Phenomena: Radiation Absorption and Scattering Effects on Photoreactors","resumen":"Heterogeneous photocatalysis employing solid semiconductors has been applied to solve a wide variety of environmental problems involving the degradation of chemical pollutants and the inactivation of pathogen microorganisms, both in gas and liquid phase. Particularly, heterogeneous photocaltaysis is able to transform refractory organics into readily biodegradable compounds, and eventually mineralized them into carbon dioxide and water. All photocatalytic reactions are initiated by absorption of radiant energy by the catalyst, which promotes an electron from the valence band to a vacant conduction band, leaving a positive hole in the valence band. These charge carriers can then participate in reduction and oxidation reactions with chemical species adsorbed on the surface of the photocatalyst. The rate of the initial radiation-activated step is proportional to the absorbed energy through a property defined as the local volumetric rate of photon absorption (LVRPA) [1]. The LVRPA represents the amount of photons that are absorbed per unit time and unit reaction volume. To evaluate the LVRPA, we must know the radiation intensity at each point inside the photocatalytic reactor. Intensity values can be obtained from the Radiative Transfer Equation (RTE). To solve the RTE in slurry reactors, in which solid catalytic particles are suspended in aqueous solutions, the optical properties of the catalyst suspension are needed.This chapter includes a derivation of the RTE together with the presentation of some methods that can be employed to solve this equation. A detailed description of the experimental method to measure and calculate the optical properties of the catalyst suspension is also given. Finally, a practical application showing the kinetic modeling of the photocatalytic degradation of an organic compound (the pharmaceutical clofibric acid) is presented. In this example, the optical properties experimentally measured are used in the LVRPA calculation.","palabras_clave":"PHOTOREACTORS|MODELLING|RADIATION"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198927,"idioma_id":5,"titulo":"El oído medio de los cinodontes basales","resumen":"La anatomía del oído medio de los cinodontes no mamaliaformes es especialmente importante para comprender las modificaciones que dieron lugar al particular oído medio observado en los mamíferos. El estribo de los cinodontes no mammaliaformes, el único hueso del oído medio de estos taxones, está bien representado en el registro fósil aunque sólo ha sido estudiado superficialmente. Se analiza aquí con detalle la anatomía del estribo de numerosos cinodontes basales en un marco filogenético, mostrando que la morfología del estribo es más variable que lo que se creía previamente. La re-evaluación de las teorías relacionadas a la posición de la membrana timpánica en cinodontes no mamaliaformes permiten concluir que la hipotética membrana timpánica postcuadrática asociada al surco escamosal es en el mejor de los escenarios relictual y probablemente no funcional dado que no hay evidencia de una conexión directa con el estribo. Las ondas sonoras eran posiblemente transmitidas al estribo desde la membrana timpánica postdentaria (soportada por la lámina refleja del angular) a través del cuadrado. Nuestro análisis resulta en una mejor comprensión del sistema auditivo en cinodontes no mamaliaformes y su evolución, resaltando la variabilidad de la anatomía del estribo y la dificultad de poner a prueba hipótesis funcionales debido a la falta de análogos modernos.","palabras_clave":"ESTRIBO|MEMBRANA TIMPÁNICA|CINODONTES NO MAMALIAFORMES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198953,"idioma_id":5,"titulo":"Economías social, trabajo y subsunción al Capital. Aproximaciones teóricas para una discusión sobre el carácter de estas nuevas experiencias productivas","resumen":"La economía social ha reaparecido con inusitada fuerza en las ciencias sociales desde hace varios años. Ese heterogéneo campo de cooperativas de trabajadores, empresas recuperadas, economías comunitarias y populares, ha tomado gran espesor, luego de la profunda crisis de 2001. Una gran parte del debate sobre la misma se enmarca en las potencialidades de dichas experiencias para configurar formas nuevas de relacionamiento social, modos nuevos de producción que tengan la potencia de crear relaciones sociales no mercantilizadas, atravesadas por los principios de la cooperación y la solidaridad.Sobre esta discusión, que desarrollamos en el primer punto del presente trabajo, planteamos una serie de interrogantes. Estas dudas se disparan a partir de reconocer una serie de transformaciones productivas del capitalismo, por lo tanto, aquello que puede pasar como efecto no deseado del capital, tal como descenso en el empleo formal, heterogeneidad productiva, fragmentación del mundo del trabajo, etc., quizás deba ser pensado como condición de funcionamiento para otorgar una nueva dinámica al patrón de acumulación.  Este problema se desarrolla en el segundo punto del trabajo.Finalmente, planteamos algunas razones sobre la subordinación y funcionalidad de estas formas de trabajo a las nuevas exigencias de acumulación que reclama el capitalismo. Sin embargo, cabe la aclaración, consideramos los procesos históricos de forma dinámica y contradictoria, de manera que la estrategia en la que se inscriben estas experiencias de economía social actualmente, de subsunción al capital, no las condena para siempre a ocupar ese lugar.","palabras_clave":"Economía Social|Trabajo|Subsunción"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":198995,"idioma_id":4,"titulo":"Factors Influencing Creep of Cracked Fibre Reinforced Concrete: What We Think We Know & What We Do Not Know","resumen":"The significance of the creep behaviour of fibre reinforced concrete (FRC) in the cracked state is a matter of debate. As FRC in service could be in the cracked state, the serviceability and failure will depend on the stability of the cracks, and the alteration of the capacity to transfer stresses. Based on the present knowledge, this paper discusses factors influencing the creep of cracked FRC to facilitate further discussions. Effects of load, temperature and humidity, and the importance of progressive debonding and pull-out, creep of the fibres and crack propagation under sustained loading have been discussed for steel and polymer fibres.","palabras_clave":"Fibre reinforced concrete|Creep behaviour|Pull-out|Steel fibres|Polymeric fibres"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199014,"idioma_id":5,"titulo":"El estudio de la diversidad del ADN mitocondrial en poblaciones humanas del Noroeste de Patagonia: estado actual y perspectivas futuras.","resumen":"En los últimos años el estudio de la diversidad genética mitocondrial se convirtió en una herramienta de gran utilidad para comprender el modo del poblamiento, los cambios demográficos que tuvieron lugar desde el poblamiento inicial, así como los procesos y eventos que dieron forma a la estructura que presentaron las poblaciones humanas a lo largo del tiempo. En el caso de la región del Noroeste de Patagonia los estudios bioantropológicos tradicionalmente se han restringido a la obtención y análisis de datos morfológicos en tanto que la información genética molecular aún no ha sido puesta en discusión. En este contexto, el objetivo de este trabajo es realizar un análisis exploratorio de la diversidad de linajes maternos de las poblaciones humanas del Noroeste de Patagonia, utilizando secuencias de ADNmt publicadas previamente. En primer lugar, se estimó la variabilidad haplotípica y nucleotídica para toda la muestra y para cada haplogrupo y se construyeron redes moleculares. Asimismo, se reconstruyó una genealogía molecular y se calculó el tiempo para el ancestro común más reciente de cada región geográfica y del haplotipo más frecuente. Los resultados indican la existencia de altos niveles de variación en el Noroeste de Patagonia, comparado con lo observado para el Sur de esta región. En el Noroeste de Patagonia el linaje más representado en el área fue el D (40.99%), seguido del B (28.83%), el C (22.97%) y por último el haplogrupo A (7.21%). Dentro del haplogrupo de D, el haplotipo más diverso fue el D1g1. Teniendo en cuenta la totalidad de los linajes utilizados fue posible predecir un poblamiento de la región entre los 15.000 y 10.000 años AP. La variabilidad genética encontrada puede deberse a procesos migratorios y\/o evolutivos, como también a procesos demográficos que fueron teniendo lugar a lo largo del tiempo hasta la actualidad","palabras_clave":"polimorfismos genéticos|haplotipos del ADNmt|genealogía molecular|métodos estadísticos moleculares"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199105,"idioma_id":5,"titulo":"Memoria Colectiva y Representaciones Sociales de la Historia","resumen":"Pensar a la memoria y a la historia desde la psicología social implica el ejercicio de situarse en la interacción, en el espacio en donde lo individual y lo colectivo se entrelazan haciendo surgir una tercera dimensión que permite comprender cómo la realidad social se inscribe en las personas, la forma en que la representan y la interiorizan, y como se traslada a otros. Moscovici (1970) denominó a esta perspectiva Psicología Social Tripolar ya que permite comprender los procesos a través de los cuales los objetos adquieren nuevos significados moldeando las visiones de los individuos y creando una realidad psicosocial compartida con los demás (Pérez, 2004). Halbwachs (1952\/1992) habla de memoria colectiva refiriéndose a una imagen del pasado que se reconstruye de manera consonante con los pensamientos que predominan en una sociedad. A través de la historia se puede identificar una trayectoria a la que subyace la esencia de la identidad grupal y su relación con otros grupos. Hay en la historia una narrativa que les dice a los miembros de un grupo quiénes son, de dónde vienen y hacia dónde van. En este marco, no se debe confundir a la memoria colectiva con la memoria histórica que refiere a los eventos que sucedieron objetivamente y están documentados. La memoria colectiva tiene que ver con el recuerdo que sobre los eventos elabora un determinado grupo social, se compone de las experiencias personales, de los hechos vividos o los relatos transmitidos. La inserción de los estudios de la memoria colectiva, desde la última década del siglo pasado, en dinámicas funcionales e intergrupales complejas, han hecho que se convierta en un objeto de estudio con características similares a los planteados por la teoría de las Representaciones Sociales (Haas y Jodelet, 2000). En este sentido, la memoria es un elemento clave de aquello que se pone en juego en los conflictos, por lo que la memoria colectiva es considerada como un conjunto de representaciones sociales controvertidas (Moscovici, 1988). En lo que hace a la Historia, de ella se desprenden por lo menos tres representaciones que ofrecen distintas versiones en sus contenidos, más o menos en tensión o conflicto: la historia escolar, la académica y la cotidiana. La primera se vincula a los libros de texto y al currículo educativo, la académica o historiográfica es la cultivada por los historiadores y científicos sociales siguiendo una lógica disciplinaria de un saber instituido en determinadas condiciones sociales e institucionales, la tercera es la historia cotidiana, que se relaciona con la memoria colectiva y está inscripta en la mente de los ciudadanos (Carretero, Rosa y González, 2006; Rosa, 2006). Liu y László (2007) sostienen que las representaciones sociales de la historia estructuran la situación objetiva a través de procesos de interpretación selectiva, de atribuciones sesgadas y evaluaciones restringidas de legitimidad. Retomando a Werscht (2002), indican que la experiencia histórica acumulada resulta en la formación de plantillas narrativas cognitivas1 sobre las que se interpretan y estructuran las nuevas experiencias, recurriendo a patrones históricos. Estas plantillas resumen los dilemas históricos centrales que las personas enfrentan a través de la historia, e imponen una trama que se estructura en una serie de personajes, eventos y circunstancias específicos. En esta trama, los eventos históricos imparten lecciones y las figuras históricas transmiten valores, por lo que es en el consenso respecto de los héroes y villanos de la historia que se simbolizan los valores y logros a los que los grupos aspiran, y también los que se rechazan (Liu y Hilton, 2005). En este capítulo se comentan los hallazgos obtenidos en estudios locales y transculturales orientados a evaluar los eventos y personajes de la historia universal y argentina en personas adultas, la importancia y las valoraciones que le atribuyen, así como las emociones que les suscitan, y los posicionamientos diferenciales que alrededor de ellos se conforman. La información se enmarca en cuatro ejes relevantes aportados por la literatura sobre la problemática: los sesgos transculturales (Páez et al. 2007), la lógica héroes y villanos (Hanke et al. 2015); las representaciones hegemónicas y polémicas (Zubieta y 1 Cognitive Narrative Templates 3 Barreiro, 2014) y las dimensiones de Calamidades Históricas, Progreso Histórico y Resistencia a la opresión histórica (Liu et al., 2012).","palabras_clave":"MEMORIA COLECTIVA|REPRESENTACIONES SOCIALES|HISTORIA|PSICOLOGIA SOCIAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199189,"idioma_id":4,"titulo":"SYNTHESIS, ACTIONS AND PERSPECTIVES OF NITRIC OXIDE IN PHOTOSYNTHETIC ORGANISMS","resumen":"After the strong influence of a series of works made around the turn of the century, nitric oxide (NO) is now considered a signal molecule with broad participation in the physiological processes of plants. NO acts as a signal in plant-microbe interactions, in plant responses to abiotic stresses, regulation of stomatal opening and gas exchange between plants and environment, and it is an essential cue in plant growth and development. This chapter will highlight key aspects of the diversity of biosynthetic pathways of NO in uni- and multicellular photosynthetic organisms, as well as its metabolism and interactions with cellular components. This review will focus in particular on the biological functions of NO in plants, with emphasis on the fundamental role played by NO in hormones´ signaling. The molecular mechanisms underpinning the NO actions in plant cells will also be addressed. The knowledge of NO biology in photosynthetic organisms showed a unique growth rate during the last years. It is tempting now to think that the acquired wisdom in the plants field might positively influence research in animal systems through innovative ideas and strategies.","palabras_clave":"Nitric Oxide|photosynthetic organisms"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199258,"idioma_id":4,"titulo":"Cytological features of penaut genome","resumen":"The genus Arachis is composed of 82 species (Krapovickas and Gregory 1994; Valls and Simpson 2005; Valls et al 2013; Santana and Valls 2015) mainly distributed within a large region of South America, which extends from the eastern foothills of the Andes Mountains in Bolivia and northern Argentina to the Atlantic coast in Brazil, and from the southern limit of the Amazonian rainforest towards the northern coast of La Plata River in Uruguay. Based on morphology, cross-compatibility, viability of the hybrids, geographic distribution and cytogenetics, the Arachis species have been arranged in nine taxonomic sections: Trierectoides, Erectoides, Procumbentes, Rhizomatosae, Heteranthae, Caulorrhizae, Extranervosae, Triseminatae and Arachis (Krapovickas and Gregory 1994; Fernández and Krapovickas 1994; Lavia 1996; Valls and Simpson 2005). Cross compatibility, karyotypic and meiotic analysis also allowed the identification and description of six different genomes within the section Arachis: namely A, B, D, F, K and G (Smartt et al 1978; Stalker 1991; Robledo and Seijo 2008, 2010; Robledo et al 2009; Silvestri et al 2015). The genomic constitution of the remaining species of the genus, in the absence of comprehensive cytogenetic and molecular analysis, is less precise and have been traditionally assigned on the basis of the subgeneric divisions, that is: Am (Heteranthae), C (Caulorrhizae), E (Trierectoides, Erectoides and Procumbentes), Ex (Extranervosae), T (Triseminatae) and R (Rhizomatosae) (Smartt and Stalker 1982). Classical and modern molecular cytogenetics revealed a huge variability within and among species of different sections. These studies provided important information about the complexity of the peanut genome, and  were  very useful to unravel the taxonomy of the genus and to establish relationships among the wild species with the cultivated peanut. Here we present an update of the cytological information on Arachis species, and some examples in which the use of chromosome markers were decisive to understand critical and long lasting problems in the genus.","palabras_clave":"genome|Arachis|FISH|heterochromatin"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199264,"idioma_id":4,"titulo":"Synthesis and applications of carbohydrate-based polyurethanes","resumen":"Polyurethanes are one of the most important and widespread type of polymers which display a wide range of industrial and biomedical applications. The recent approaches and advances in polyurethane research involve the replacement of petro-based polyols and isocyanates with bio-based molecules. In this regard, carbohydrates offer a great promise due to their rich functionality, varied stereochemistry and renewable production on an impressive scale. The carbohydrate-based polyurethanes are also prone to be biodegradable and biocompatible. These type of materials may be entirely derived from carbohydrates or contain carbohydrates as pendant groups or as constituents of the soft part of the polymer. Artificial polymers prepared by combination of polysaccharides with synthetic monomers or polymers are also included. The synthesis of these materials is described, and their actual or potential applications (mostly in biomedicine, as implants for tissue repair, as permanent or temporary prosthesis or as drug delivery systems) are discussed.","palabras_clave":"POLYURETHANE|CARBOHYDRATE|BIOPOLYMER|ARTIFICIAL POLYMER"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199357,"idioma_id":5,"titulo":"Memorias fotográficas: dispositivos visuales y pasado reciente en Argentina","resumen":"¿De qué manera la creación de singulares dispositivos fotográficos construye memorias acerca del pasado reciente de una sociedad? La fotografía, en su peculiar condición de ida y vuelta entre índice y artefacto, ha sido a menudo soporte y vehículo de memorias sociales. Ciertas obras fotográficas argentinas posdictatoriales evocan una historia traumática común, sin estricta pretensión documental pero interesadas en mantener de diversas formas los vínculos con lo vivido. Son obras que, en sus mismos procedimientos de construcción de lo real, se han conformado como memorias fotográficas de un pasado traumático  -conjugando la posibilidad doble de lo fotográfico de ofrecerse como huella del mundo y despliegue a la vez de nuevos mundos construidos. Las imágenes presentadas a continuación forman parte de este conjunto: a partir de la fotografía construyen dispositivos visuales que ofrecen una distancia para descifrar la dolorosa experiencia colectiva de la pasada dictadura cívico-militar .","palabras_clave":"MEMORIAS FOTOGRAFICAS|ARGENTINA|FOTOGRAFIA CONTEMPORANEA|IMAGEN"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199401,"idioma_id":5,"titulo":"Reestructuración de las áreas comerciales 'a cielo abierto' en el sur de la región metropolitana de Buenos Aires","resumen":"En los 2000, parecería que las lógicas subyacentes a los nuevos 'objetos urbanos' no alcanzan para describir el escenario metropolitano de Buenos Aires y que, a diferencia de lo que sucedía en los 90, resulta necesario atender a otras dinámicas, incluyendo el sector comercial. En este sentido, la transformación de las tipologías y el patrón de localización del comercio 'de calle' en las subcentralidades del corredor sur de la región metropolitana muestran algunas especificidades sobre las que busca indagar este artículo. Dentro de este marco, en primer lugar, se describen las especificidades de los municipios de la primera corona del corredor sur en relación a la estructura del transporte, algunas características socio-demográficas y patrones de la movilidad cotidiana. En la segunda parte del trabajo, se hace foco sobre las principales áreas centrales de estos municipios -entorno de las estaciones ferroviarias de Lanús y Lomas de Zamora, y de la Av. Bartolomé Mitre en Avellaneda-, con eje en el análisis de los recientes procesos y patrones de localización de las franquicias, y sus sinergias con otras actividades comerciales y de servicio. Por último, se plantea una categorización de los subcentros estudiados en relación a las características formales y funcionales del comercio y de los espacios de movilidad asociados.","palabras_clave":"CENTRALIDAD|REESTRUCTURACIÓN COMERCIAL|MOVILIDAD COTIDIANA|CONURBANO BONAERENSE"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199415,"idioma_id":4,"titulo":"Importance of Glutathione in the Legume-Rhizobia Symbiosis","resumen":"Glutathione (GSH) is essential for the proper development of root nodules during the symbiotic association of legume and rhizobia. It is involved in the antioxidant defense, the detoxification of xenobiotics, and the tolerance to abiotic and biotic stresses. The high level of GSH in root nodules and the presence of an active ascorbate-glutathione (AsA-GSH) cycle suggest that GSH participates in the protection of the nitrogen-fixing process against reactive oxygen species (ROS) resulting from the active nodule metabolism. Glutathione-related enzymes also play a critical role in defense against ROS: (a) glutathione peroxidase (GPX) is a H2O2 scavenger that uses GSH as a reductant, (b) glutathione reductase (GR) reduces GSSG using NADPH as a source of reducing power and maintaining the GSH\/GSSG ratio in cells, (c) glutathione-S-transferase (GST) catalyzes the nucleophilic conjugation of GSH with several electrophilic substrates, and (d) glutaredoxins (GRXs), small redox proteins from the thioredoxin (TRX) superfamily, use GSH as electron donor. In this chapter, the role of GSH and its related enzymes was analyzed in free-living rhizobia and in the symbiosis with the legumes as well as the responses to different abiotic stresses (acid pH, saline, drought, and heavy metals\/metalloids).","palabras_clave":"GLUTATHIONE|PLANTS|STRESS TOLERANCE|BIOLOGICAL NITROGEN FIXATION"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199463,"idioma_id":4,"titulo":"Molecular and Cellular Aspects of Mammalian Sperm Acrosomal Exocytosis","resumen":"During capacitation, sperm activate a complex cascade of signaling pathways leading to acquire two essential features: the development of hyperactivated motility and the ability to undergo acrosomal exocytosis upon stimulation with the proper stimuli. Mammalian sperm must undergo acrosomal exocytosis to penetrate the extracellular matrix surrounding the egg, named zona pellucida (ZP). Acrosomal exocytosis shares many molecular mechanisms in common with other cellular secretory processes. However, there are some features that make this process a special type of regulated secretion: a single exocytotic granule per cell is involved; there is no membrane recycling; and rather than a single vesicle-plasma membrane union point, fusion between the outer acrosomal and the plasma membranes occurs at multiple sites to destabilize the structure of the acrosome. Protein kinase A (PKA) plays a pivotal role in almost all known aspects of sperm capacitation, not only restricted to fast events. In mouse sperm, PKA coimmunoprecipitates with the tyrosine kinase Src.","palabras_clave":"SPERM|CAPACITATION|FERTILIZATION|ACROSOME"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199498,"idioma_id":4,"titulo":"Cytological features of peanut genome","resumen":"The genus Arachis is composed of 82 species mainly distributed within a large region of South America, which extends from the eastern foothills of the Andes Mountains in Bolivia and northern Argentina to the Atlantic coast in Brazil, and from the southern limit of the Amazonian rainforest towards the northern coast of La Plata River in Uruguay. Based on morphology, cross-compatibility, viability of the hybrids, geographic distribution and cytogenetics, the Arachis species have been arranged in nine taxonomic sections: Trierectoides, Erectoides, Procumbentes, Rhizomatosae, Heteranthae, Caulorrhizae, Extranervosae, Triseminatae and Arachis. Cross compatibility, karyotypic and meiotic analysis also allowed the identification and description of six different genomes within the section Arachis: namely A, B, D, F, K and G . The genomic constitution of the remaining species of the genus, in the absence of comprehensive cytogenetic and molecular analysis, is less precise and have been traditionally assigned on the basis of the subgeneric divisions, that is: Am (Heteranthae), C (Caulorrhizae), E (Trierectoides, Erectoides and Procumbentes), Ex (Extranervosae), T (Triseminatae) and R (Rhizomatosae). Classical and modern molecular cytogenetics revealed a huge variability within and among species of different sections. These studies provided important information about the complexity of the peanut genome, and  were  very useful to unravel the taxonomy of the genus and to establish relationships among the wild species with the cultivated peanut. Here we present an update of the cytological information on Arachis species, and some examples in which the use of chromosome markers were decisive to understand critical and long lasting problems in the genus.","palabras_clave":"ARACHIS|CYTOLOGICAL FEATURES|GENOME"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199509,"idioma_id":4,"titulo":"Modified Starches Used as Additives in Enhanced Oil Recovery (EOR)","resumen":"Nowadays, oil recovery involves mainly three phases: primary, secondary and tertiary. In primary phase, natural pressure of the reservoir is employed to push crude oil to the surface, allowing a yield up to 10 %. In the second one, pressurized gas and water are injected to recover part of the oil remnant (~ 30 %). However, heterogeneous nature of the reservoirs hinders the complete oil phase extraction. Thus, a tertiary phase emerged called Enhanced Oil Recovery (EOR). This is considered a multidisciplinary area which involves not only scientific but also technological concepts in order to develop new methodologies to enhance the crude oil extraction and to extend the production life of oilfields. EOR implementation arises as a supplementary technology to conventional ones, optimizing the not-easily recoverable oil phase. Within this context, the estimation of oil remnant in reservoirs approaches to 7.0 x 1012 barrels, after primary and secondary recoveries are concluded. One of the strategies proposed for EOR implies the use of sophisticated displacing fluids which are pumped into the reservoir forcing the oil to flow towards the production wells. For this purpose, several ionic polymers are added to flood water to enhance oil extraction mainly through two different mechanisms. On one hand, these displacing fluids force the oil out of the pores and the rocks surfaces. On the other hand, the use of these sophisticated fluids allows reducing water permeability through rocks surfaces.  Even though several water-soluble polymers are currently being used, starch is considered as a good alternative to employ in tertiary recovery due to its wide availability, stability and inherent environmental friendliness. Thus, the state of the art related to the use of different starch derivatives in EOR is included in this chapter. Besides, diverse methodologies used to synthesize modified starches are presented, analyzing the optimal conditions of each reaction. Particularly, the synthesis of cationic and crosslinked starches are reported since these modified starches are the most used in EOR. Modification degree as well as physicochemical properties of the derivatives are included and well discussed in this chapter. Rheological and flow properties of displacing fluids are also discussed as a function of starch concentration.","palabras_clave":"ENHANCED OIL RECOVERY|STARCH DERIVATIVES|CATIONIC AND CROSSLINKED STARCHES|CHEMICAL SYNTHESIS|MODIFICATION DEGREE|PHYSICOCHEMICAL PROPERTIES|RHEOLOGICAL AND FLOW PROPERTIES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199587,"idioma_id":5,"titulo":"Herpetofauna de las dunas costeras bonaerenses","resumen":"Las dunas costeras se encuentran entre los ecosistemas más amenazados del neotrópico. En Argentina, los principales campos de dunas se encuentran localizados en las provincias de Buenos Aires y Río Negro. Aquellos localizados en Buenos Aires son los más importantes en cuanto a superfcie y estarían incluidos dentro de la región pampeana; mientras que aquellos ubicados en Río Negro, de menor superfcie, pertenecerían a las regiones del espinal y del monte (Cabrera, 1976). Actualmente, dentro de las dunas pampeanas, solo restan unos pocos parches de hábitat en relativamente buen estado de conservación, lo que ha llevado a autores como Bilenca y Miñarro (2004) a declarar estos sitios como ?Áreas Valiosas de Pastizal para Sudamérica?.","palabras_clave":"Reptiles|Anfibios|Dunas Costeras|Conservación"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199674,"idioma_id":4,"titulo":"ANIMAL DIVERSITY, DISTRIBUTION AND CONSERVATION","resumen":"In this chapter, we summarize the ecological information available on the species of arthropods, reptiles, terrestrial birds and mammals known to occur at Península Valdés, within the context of the Monte and Patagonia eco-regions. Two hundred species of insects and spiders, 12 species of reptiles, 139 species of birds and 23 species of native mammals inhabit today the island-like peninsula. We describe thecommunity structure, distribution and abundance of the different taxa according to current knowledge. As the Península Valdés region is a World Natural Heritage Site and a provincial protected area of high importance for the conservation of biodiversity and the regional economy, we found relevant to summarize knowledge on the effects of human activities on different components of biodiversity. Habitat degradation, grazing by domestic sheep and poaching are major threats to wildlife, although Península Valdés still harbours some of the most abundant populations of wild species in Patagonia. It is a priority to implement the management plan available for Península Valdés, taking into account the interactions between biodiversity, the different human activities and the physical environment. At the same time, it is necessary to identify and implement actions to conserve wild species and habitats, and also to develop programmes for the coexistence of responsible human activities and healthy wildlife populations.","palabras_clave":"BIODIVERSITY|HUMAN ACTIVITIES|CONSERVATION|PENINSULA VALDES|PATAGONIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199678,"idioma_id":5,"titulo":"La CGT en Jujuy en tiempos del primer peronismo: contextos, actores y dinámicas","resumen":"Desde hace casi dos décadas vienen enriqueciendo el horizonte historiográfico estudios que, anclados en espacios provinciales o locales, complejizan la mirada sobre los tiempos constitutivos del peronismo. Existe la presunción de que al momento de inaugurarse este proceso el interrogante sobre los vínculos entre los obreros y el peronismo podía considerarse saldado por la amplia bibliografía que, desde las clásicas obras de Gino Germani (1955, 1962) hasta la última contribución de Torcuato Di Tella (2003), se había ocupado de la cuestión. Sin embargo, subsisten aún lagunas en el conocimiento de las alternativas que atravesó el movimiento obrero en aquellos años en varias regiones del interior del país, realidad que reclama análisis encarados a través de operaciones de contextualización compleja, capaces de extirpar prejuicios todavía vigentes sobre sus orientaciones políticas y culturales. Tanto la integración de los trabajadores a las estructuras de la Confederación General del Trabajo (CGT) como el involucramiento de los sindicatos no confederados en la dinámica gremial y política provincial a través de los canales de interacción configurados por la Central Obrera presentaron aristas complejas. El camino de su afianzamiento fue sinuoso en una provincia en donde el oficialismo era abrumadoramente de origen radical y no necesitó dirimir con el peronismo disidente el rumbo de sus políticas debiendo, por lo demás, abrirse espacio en un movimiento obrero signado por la impronta socialista y por la intensa expectativa generada por el breve derrotero del Partido Laborista que dieron cauce en las tierras del azúcar a un sindicalismo de marcada tendencia autonomista. Rescatando actores e iniciativas, y reconstruyendo contextos, el artículo pretende arrojar alguna luz sobre estos procesos.","palabras_clave":"CGT|Jujuy|actores|contextos"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199763,"idioma_id":5,"titulo":"Empresa, Producción y Costos","resumen":"Conceptos básicos y ejercitación sobre el tema","palabras_clave":"MICROECONOMIA|APLICACIONES|BASICA|MERCADOS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199801,"idioma_id":5,"titulo":"Introducción: Metamorfosis políticas del Mal","resumen":"¿Por qué escribir un libro ?por qué editarlo? sobre herencias criminalesen Argentina y en Sudáfrica? La necesidad de compren d e r es larespuest a. La ?necesidad de comprensión?, que los sudafricanos asumenya en 1993 en el Epílogo de la Constitución provisional, es decir, en elmismo comienzo del trabajo de dar respues ta a un pasado criminal, dealgún modo resume el motivo de este libro que, en continuidad con eliniciado con Lesa Humanidad (Katz, 2014), se propone un nuevo esfuerzopor dar a ver la luz que el contrast e entre la experiencia argentina y lasudafricana ofrece para reflexionar sobre los debates pendiente s sobre elpasado reciente que no terminan de eclosionar pese a haber transcurridocuarent a años ya de los hechos en Argentina","palabras_clave":"LESA HUMANIDAD|PERPETRADORES|SUDAFRICA|ARGENTINA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199802,"idioma_id":5,"titulo":"¿Despolitizar? ¿Politizar? Lazo político y lesa humanidad en Argentina","resumen":"¿Puede hacerse política frente a la experiencia de gravísimas violacionesa los derechos humanos? ¿puede politizarse el horror? Pero también,¿puede negarse la naturaleza política del advenimiento de los regímenescriminales? ¿no debemos acaso reconocer el carácter político del crimeny, con ello, el carácter político de la respuesta que debemos darle? En fin,¿puede politizarse, puede despolitizarse?Sin pretender dar de antemano una definición de política, en las páginasque siguen, intentaremos dar cuenta de cómo estos interrogantes sepusieron en juego y encontraron históricamente una respuesta en tresmomentos en los que se anudó lo justo y lo político en el lazo común, o elcontrato social, de los argentinos, tres momentos que signaron eltratamiento del pasado criminal en los treinta años de democracia en Argentina: el Juicio a las Juntas, en 1985, las declaraciones del ex marinoAdolfo Scilingo en 1995 y el fallo de la Corte Suprema que declara lainconstitucionalidad de las llamadas ?leyes de impunidad? en 2005.","palabras_clave":"VIOLENCIA POLITICA|LESA HUMANIDAD|JUSTICIA|REPRESORES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199832,"idioma_id":5,"titulo":"La simulación computacional de la complejidad social","resumen":"Este trabajo se propone explorar los siguientes interrogantes ¿cómo ha surgido la simulación social como estrategia de investigación social? (sección 2); ¿qué es modelar?, ¿qué es simular? y ¿qué es la complejidad? (sección 3); ¿por qué y para quien desarrollar la simulación computacional en ciencias sociales? (sección 4); ¿cómo simular computacionalmente la complejidad social? (sección 5). El primer interrogante es de orden socio-histórico, el segundo es de naturaleza teórica y conceptual, el tercero plantea un problema de orden epistemológico y político y, finalmente, el cuarto problematiza una cuestión de metodológica. El artículo procura acercar a los investigadores sociales al campo de la simulación computacional desde un punto de vista epistemológico crítico.","palabras_clave":"COMPLEJIDAD SOCIAL|SIMULACION SOCIAL|MODELIZACION|SISTEMAS COMPLEJOS"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199852,"idioma_id":5,"titulo":"La filosofía Iberoamericana de la Historia. El largo siglo XX","resumen":"Hemos dividido el presente capítulo en cuatro secciones, cada una de las mismas organizada en torno a una cierta constelación de autores, ideas, controversias y problemas en torno al foco de la filosofía de la historia. Las secciones son : I. Irrupción del siglo XX en el pensamiento iberoamericano de la historia: de los quiebres finiseculares de la modernidad a la contra-afirmación de una modernidad latina. El ?modernismo? y el latinoamericanismo: Darío, Rodó. Positivismo, biologismo e ideales históricos en Ingenieros, Caso, Vasconcelos y Alfonso Reyes ; II.  Las recepciones periféricas de Marx en Iberoamérica y la filosofía de la historia. Mariátegui, Aricó, Pereyra, Echeverría ; III. Horizontes contemporáneos de la Filosofía de la historia. Del giro epistemológico al giro lingüístico y el horizonte de la reflexión sustantiva. Brauer, Yturbe ; IV. A guisa de conclusión. Transición al siglo XXI.","palabras_clave":"IBEROAMERICA|METAHIISTORIA|CULTURA|SIGLO XX|CONTROVERSIAS|CONSTELACIONES|MODERNIDAD|LATINO|PERIFERIA|SHAKESPEARE|HISTORIA INTELECTUAL DE LA FILOSOFIA DE LA HISTORIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":199940,"idioma_id":5,"titulo":"Sobre la productividad social de un conflicto urbano. Disputas en torno a la apropiación de la Canchita de los Bomberos (Mar del Plata, 2012-2015)","resumen":"Hacia fines de septiembre de ese mismo año, el Municipio de General Pueyrredón anuncia las tierras disponibles para comprometer en su implementación bajo la modalidad desarrollo urbanístico, entre las que figura el predio conocido como Canchita de los Bomberos en el barrio Parque Luro de la ciudad de Mar del Plata, donde se prevé la construcción de departamentos monoambientes y dúplex,en terrenos aportados por el Estado nacional. Frente a ello, rápidamente se conforma un grupo de vecinos autoconvocados en defensa de la utilización de dicho predio como espacio verde, que lleva adelante una diversidad de estrategias, incluida la presentación de un recurso de amparo ante la justicia, en vistas a manifestarse en contra de la decisión del municipio y evitar la construcción de viviendas en el lugar. Progresivamente, el conflicto suscita la aparición en escena de otros actores que también juegan un papel central en la producción de la ciudad y pugnan por legitimar sus posiciones (asociación vecinal de fomento, colegios profesionales, etc.).Aquí nos proponemos, siguiendo el abordaje de Melé (2003; 2006), reflexionar acerca de los efectos sociales que el conflicto produce en tres dimensiones: la territorialización, que refiere a las formas de apropiación simbólica delespacio que suelen reforzarse o modificarse en el proceso; a la irrupción del conflicto en el espacio público, que remite a las formas de deliberación pública en que el conflicto es procesado; y la actualización local del derecho, que alude a la juridificación del conflicto y, con ello, las resignificacionesy transformaciones que se producen una vez que ingresa al mundo del derecho (Azuela y Mussetta, 2009; Azuela y Cosacov, 2013).En este marco, nos preguntamos: ¿qué representaciones simbólicas y qué imaginarios urbanos emergen en el conflicto? ¿Trascienden el territorio e irrumpen en la esfera pública o más bien se acotan a aquél? ¿De qué forma ingresa el conflicto al mundo jurídico? ¿Se mantienen los objetivos en el corto plazo o se modifican? ¿Es posible identificar estrategias por parte del Estado en función de sus diferentes dispositivos institucionales y jurisdicciones? ¿Son coincidentes o contrapuestas? ¿Cómo se vincula este proceso a la dinámica y a la estructura urbana de la ciudad? En definitiva, ¿qué efectos sociales produce el conflicto?","palabras_clave":"POLITICAS PÚBLICAS|CONFLICTO URBANO|PRODUCTIVIDAD SOCIAL"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200032,"idioma_id":4,"titulo":"Non-Carbonaceous Electrodes for Microbial Electrochemical Systems","resumen":"Bioelectrochemical Systems (BESs) are innovative and sustainable devices. They combine biological and electrochemical processes to engineer sensors, treat wastewater and\/or produce electricity, fuel or high-value chemicals. In BESs, scientists have managed to incorporate biological catalysts, i.e. enzymes and\/or microorganisms, and make them work in advanced electrochemical cells. BESs operate under mild conditions - at close to ambient temperature and pressure and at circumneutral pH - and represent a sustainable alternative to precious metal-based systems. Incorporating biological catalysts into devices while maintaining their activity and achieving electrical communication with electrode surfaces is a critical challenge when trying to advance the field of BESs.From implantable enzymatic biosensors to microbial electrosynthesis, and from laboratory-scale systems and fundamental studies to marketed devices, this book provides a comprehensive overview of recent advances related to functional electrodes for BESs. Suitable for researchers and graduate students of chemistry, biochemistry, materials science and environmental science and technology.","palabras_clave":"MICROBIAL ELECTROCHEMICAL TECHNOLOGIES|MICROBIAL ENERGY CONVERSION|NON-CARBONACEOUS ELECTRODES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200190,"idioma_id":4,"titulo":"Power struggles in the remembering of historical intergroup conflict: hegemonic and counter-narratives about the Argentine ?Conquest of the Desert?","resumen":"The ?Conquest of the Desert?, a military campaign carried out by the Argentine State at the end of the 19th century, involved the massacre and enslavement of indigenous communities. In this chapter we analyzed the hegemonic narrative concerning this historical process as conveyed by a museum?s exhibits along with the indigenous counter-narrative as registered supported by the local Mapuche community. Our analyses show that the hegemonic narrative tends to negate the conflict between the two groups by rendering the indigenous group invisible and representing their identity in an anachronistic fashion. The counter-narrative evidences a tension between indigenous people?s need to assert their identification with their ancestors and secure recognition from the dominant group, while also allowing for change and transformation in their midst.","palabras_clave":"INTERGROUP CONFLICT|HISTORICAL NARRATIVES|HEGEMONIC NARRATIVES|COUNTER NARRATIVES|COLLECTIVE MEMORY"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200191,"idioma_id":5,"titulo":"La justicia como representación social: difusión y posicionamientos diferenciales","resumen":"El objetivo principal de este trabajo es analizar la relación entre el proceso de difusión de las representaciones sociales de la justicia por la prensa y su apropiación por parte de los lectores. Se realizaron dos estudios transversales de manera simultánea. El estudio 1 analizó el sentido y la frecuencia de aparición del término justicia en el periódico de mayor circulación de la Ciudad Autónoma de Buenos Aires. Los resultados obtenidos indican que la representación de la justicia tendría un sentido retributivo e institucional. El estudio 2 indagó la representación social de la justicia en estudiantes universitarios (N = 404) a través de la técnica de asociación de palabras. Los resultados de este estudio indican que el núcleo central de la representación social tendría un sentido retributivo e institucional, al igual que la representación difundida por el periódico de mayor circulación. Sin embargo, se hallaron diferencias en la valoración de la justicia según el periódico que los participantes informaron leer. Se concluye que existiría un movimiento circular de mutua constitución entre la representación social de la justicia difundida por el periódico de mayor circulación y la de los estudiantes universitarios. Además, las diferencias en la valoración de la justicia identifica en los elementos periféricos expresaría la existencia de posicionamientos diferenciales con respecto a una representación social hegemónica","palabras_clave":"REPRESENTACIONES SOCIALES|JUSTICIA|DIFUSIÓN|POSICIONAMIENTOS DIFERENCIALES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200416,"idioma_id":5,"titulo":"Auditoria geoambiental de la costa y monitoreo sistemático de las playas de Quequén, provincia de Buenos Aires","resumen":"El presente trabajo tiene por objetivo el estudio y monitoreo estacional de los aspectos dinámicos y sedimentológicos en el perfil de playa del área comprendida entre la escollera situada al norte de la desembocadura del rio Quequén y la zona denominada Bahía de los Vientos hasta Costa Bonita, como resultado de los cambios ambientales emergentes de la obra de extensión de la escollera Sur del Puerto de Quequén efectuada en el año 2005.","palabras_clave":"MONITOREO|PLAYA|PUERTO|RIESGO|INFRAESTRUCTURA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200464,"idioma_id":5,"titulo":"Francisco: Entre la religión, la política y la cultura","resumen":"A continuación resumire los principales ejes de análisis evidentes en los trabajos reunidos en este libro, para establecer tanto las dimensiones de la realidad social y religiosa para las cuales una figura como la de Francisco puede ser relevante, como las maneras en que los académicos creen que lo puede ser. Intentaré brindar una reseña de las múltiples dimensiones del 'efecto Francisco' apuntadas en este libro, que muestran también el estado de la agenda académica contemporánea al respecto y apuntaré algunos posibilidades de análisis futuros.","palabras_clave":"RELIGION|CATOLICISMO|SOCIOLOGÍA DE LA CULTURA|TEORIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200502,"idioma_id":5,"titulo":"Canal Beagle","resumen":"Se adjunta pdf","palabras_clave":"CANAL BEAGLE|HISTORIA|GLACIACIONES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200503,"idioma_id":5,"titulo":"Glaciar Perito Moreno","resumen":"Se adjunta el pdf","palabras_clave":"GLACIAR PERITO MORENO|HISTORIA|GLACIACIONES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200504,"idioma_id":4,"titulo":"New Strategies for Obtaining Inorganic-Organic Composite Catalysts for Selective Hydrogenation","resumen":"Pd\/composites are catalysts in which the catalytically active metal phase is located in asmall layer on the support surface. The metal distribution obtained on these supportscorresponds to a structure commonly known as ?egg-shell?. This distribution is optimalfor reactions that have heat or mass transfer resistances. The small thickness of the metallayer is mainly attributed to the use of support pellets of mixed organic?inorganiccomposition, the special interaction between the hydrophobic?hydrophillic supportsurface and the metal species (Pd or Pt) present in the impregnating aqueous solution.Pd\/composite catalysts are active and selective for the reactions of selective hydrogenationof styrene, 1-heptyne, 3-hexyne and 2,3-butanone, and enantioselective hydrogenationof ethyl pyruvate. These reactions are of interest in both academic and industrialaspects.","palabras_clave":"Hydrogenation|Composite suppport|egg-shell catalyst"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200668,"idioma_id":5,"titulo":"El MERCOSUR en aprietos...¿crisis en la Integración sub-regional?","resumen":"Una vez más los gobiernos latinoamericanos apelan al regionalismo como instrumento para afrontar los desafíos que plantea el mundo global, obligando a repensar las estrategias de inserción regional e internacional en el marco de las dinámicas globales contemporáneas. Estas dinámicas son una expresión de varios factores: el debilitamiento de los centros del poder mundial y de su capacidad económica con el desplazamiento del eje de gravedad hacia los países emergentes (China, India, Brasil, Sudáfrica); la crisis económico-financiera en los EE.UU. y Europa que condujo al estancamiento de la integración europea a partir de la crisis de la deuda de la eurozona y la salida del Reino Unido; el protagonismo de Asia-Pacífico en las corrientes comerciales, financieras y de inversión al tiempo que adquirió un posicionamiento estratégico en cadenas de valor global; las transformaciones socioeconómicas acaecidas por el cambio tecnológico que fragmentó las cadenas productivas generando una relocalización de las actividades, produciendo tensiones entre la esfera trasnacional, en la que se desarrollan las actividades económicas y financieras, y la nacional; la emergencia de grandes espacios -continentales y regionales- y el surgimiento de nuevas coaliciones a nivel mundial, tal como las negociaciones de convergencia de intereses entre los EEUU y la UE en el Acuerdo Transatlántico sobre Comercio e Inversión (TTIP) y entre Canadá y la UE en el Acuerdo Económico y Comercial Global (AECG); además de otras negociaciones mega-regionales como el Acuerdo de Asociación Transpacífico (TPP) y la Asociación Económica Regional Integral (RCEP), las cuales dejan por fuera a la mayoría de los países latinoamericanos; la pérdida de importancia relativa de la OMC frente a las nuevas regulaciones surgida de los TLC por la erosión que sufrieran los regímenes internacionales de comercio e inversiones debido a la falta de avances en las negociaciones multilaterales como la Ronda de Doha; la aplicación de estrategias defensivas por parte de los Estados para mitigar los efectos adversos de la economía global a través de una multiplicidad de TLC en los que se han negociado concesiones OMC-plus y\/o OMC extra -con efectos de retroalimentación virtuosa sobre la misma economía global- o mediante la adopción de agendas complementarias.","palabras_clave":"REGIONALISMO|INTEGRACION|COMERCIO|RELACIONES INTERNACIONALES"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200699,"idioma_id":4,"titulo":"Wax esters and triacylglycerol biosynthesis in bacteria","resumen":"Bacteria are an extremely diverse group of organisms, some of which possess the ability to synthesize and accumulate neutral lipids, such as triacylglycerols (TAG) and wax esters (WE). Among these microorganisms, Actinobacteria are specialized in the accumulation of TAG, whereas Gram-negative Proteobacteria, such as Acinetobacter and Marinobacter, produce predominantly WE. The capability for accumulating large amounts of TAG seems to be restricted to some members of Actinobacteria, such as those belonging to Rhodococcus, Gordonia, and Streptomyces genera, and to the Gram-negative Alcanivorax borkumensis. The biosynthesis and accumulation of TAG and\/or WE require the occurrence of a set of genes\/proteins working in a coordinated metabolic and regulatory context in the cell. Some components of the lipid-accumulating machinery in native producers have been identified and characterized. They include genes coding for: (1) enzymes catalyzing the last reactions of TAG and\/or WE synthesis; (2) enzymes involved in the reduction of fatty acids to the respective fatty alcohols for the synthesis of WE; (3) enzymes of central metabolism which generate NADPH for fatty acid synthesis; (4) a structural protein involved in the assembly and stabilization of lipid inclusion bodies; and (5) a lipid transporter protein involved in the balance and homeostasis of cellular lipids. Some of these genes identified in native producers have been used for engineering bacterial hosts, which are naturally unable to produce these lipids, in order to produce TAG\/WE with bacterial strains of biotechnological relevance.","palabras_clave":"TRIGLYCERIDES|WAXES|BIOSYNTHESIS|BACTERIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":200903,"idioma_id":5,"titulo":"La defensa oral","resumen":"El presente libro es una versión aumentada del que ya se publicara en el año 2009 en el marco de la Cátedra de Taller de Elaboración de TRabajo Final de la Licenciatura en Comunicación Social de la Universidad Nacional de La Matanza. [...] Desde el punto de vista teórico, la cátedra de Taller de Elaboración de Trabajo Final, abreva en el marco epistémico más general del constructivismo, y en las concepciones que articulan la evaluación de los procesos y los productos desde la perspectiva comunicacional de la Educación. [...]","palabras_clave":"TRABAJO FINAL|MARCO TEORICO|TEMA CIENTIFICO|METODOLOGIA DE LA INVESTIGACION"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":201000,"idioma_id":4,"titulo":"Conflicting Narratives about Argentinean 'Conquest of the Desert'. Representations, cognitive Polyphasia, and Nothingness","resumen":"This chapter looks into how people account for an Argentine historical process called the ?Conquest of the Desert&#8223; (i.e. a military campaign that was undertaken by the Argentine government from 1874 to 1885). Since 1880 this campaign has been very important in the official master narrative in Argentina. However, recent insights from different disciplinary perspectives have given rise to important debates about this master narrative. Although the traditional view is still present in different symbolic resources such as textbooks, museums or monuments, it conflicts with a revisionist narrative that emphasizes the slaughter of indigenous people perpetrated by the Argentine State during this process. The contribution of SR theory to understand how individuals acquire the group?s past, constituting their national identity, will be discussed. Specifically, we will consider the role of SR in understanding how the power struggle among social groups shapes collective memory. Also, their role in the way individuals think about history, determining what can be collectively signified and what can be excluded from the real sphere, will be scrutinized. Finally, we will examine what this implies for intervening in students&#8223; history learning and the possibilities to transform common sense knowledge into the disciplinary knowledge of history.","palabras_clave":"COLLECTIVE MEMORY|HEGEMONIC NARRATIVES|NOTHINGNESS|COGNITIVE POLYPHASIA"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":201048,"idioma_id":5,"titulo":"Capítulo 5. Aportes del estudio de representaciones sociales a la investigación educativa. Representaciones sociales de estudiantes de enfermería sobre la vejez.","resumen":"Este capítulo presenta resultados de una investigación realizada en el Departamento de Salud Comunitaria de la Universidad Nacional de Lanús (unla). Esta investigación surge a partir de una reflexión crítica sobre el lugar de la universidad como institución formadora de futuros profesionales que puedan pensar la vejez desde un posicionamiento que reconozca el bagaje histórico, social y cultural, contextuado espacio-temporalmente respecto de las concepciones y prácticas realizadas sobre dicho grupo poblacional.En concordancia con la misión primaria de la unla de contribuir al desarrollo económico, social y cultural de la región, y su inserción y desarrollo en la comunidad (Jaramillo, 2003), a través de la producción y distribución de conocimientos y de innovaciones científico-tecnológicas, esta investigación pretendió atender las problemáticas sociales en la que nos hallamos inmersos.","palabras_clave":"Representaciones Sociales|Investigación Educativa|Vejez|Enfermería"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":201071,"idioma_id":5,"titulo":"Circuitos productivos, territorio y redefinición de las estrategias de las empresas multinacionales","resumen":"p { margin-bottom: 0.25cm; direction: ltr; line-height: 120%; text-align: left; }Enel marco del desarrollo del denominado capitalismo global, elterritorio, la industria y las relaciones sociales de producción hanexperimentado una proceso de transformación intenso, que entre otrosresultados trajo aparejado un cambio en la morfología de lasciudades y la lógica de localización de las empresas,principalmente las grandes industrias manufactureras. Estos cambiossiguiendo a Mattos, fueron generadas por el agotamiento del paradigmade producción fordista y la introducción del modelo flexible,proceso que guió dichas transformaciones urbanas. Así, las empresasmultinacionales desarrollaron una dinámica de expansión ydespliegue a través de un ?espacio mundial de acumulación?,configurando una nueva arquitectura productiva de expansiónterritorial.Entérminos territoriales, el impacto en la ciudad capitalista se dioprincipalmente en su funcionamiento y las formas de expansión, apartir de los cuales se generaron procesos de periurbanización ydeslocalización de áreas centrales, donde se vislumbra una ?ciudad difusa?, sin centro cuyos nodos compiten y cooperan. Este fenómeno,también abordado desde la perspectiva del desarrollo local, impulsóuna lógica de segregación espacial de la ciudad donde losterritorios buscan ser atractivos para el capital, generando unalógica de competencias en el mercado global.Estosprocesos impactan también en el mercado de trabajo y en lasrelaciones sociales de producción, es decir este proceso decompetencia de los espacios locales tiene incidencia en aquelloslugares donde las empresas están instaladas, y donde los individuostambién compiten con los de otros territorios. En tal sentido esimportante destacar que si bien estos espacios locales o espacioseconómicos en competencia están diferenciados desde el punto devista económico o del capital, no es así para los individuos quecirculan por ellos, y cuyas demandas de empleo trascienden losintereses del capital y su relación con el espacio. Por otra partese establece una relación particular entre empresa y gestión local,donde se establecen acuerdos de cooperación, en los cuales laempresa demanda condiciones apropiadas para su funcionamiento ?ofertade capacitación, políticas públicas tributarias y\/oadministrativas, entre otras- y el gobierno local genera condicionesen el marco de la competencia con otros espacios locales. Creemos,a modo de pregunta que guie el trabajo, que esta relación empresaterritorio se relaciona con los cambios introducidos con el paradigmade la producción flexible y políticas neoliberales, que si bien enArgentina ha habido un proceso de revertirlo, persistenprincipalmente por el contexto de liberalización del capital a nivelglobal. Como segunda pregunta surge la idea en torno a la inscripciónterritorial del capital y su relación con los espacios locales encompetencia como modo de controlar y reducir los conflictossindicales o laborales.Pararesolver estas preguntas ?o formular otras nuevas-, este capítuloindagará sobre la temática sobre tres ejes, con niveles de análisisdistintos. El primero, un nivel macro social, donde abordaremos demanera teórica esta problemática, poniendo énfasis en algunosconceptos clave sobre la temática. El segundo apartado, de caráctermeso social, será el análisis de de las empresas multinacionales,principalmente manufactura industrial y servicios, en función de lasdistintas lógicas de articulación con el Estado ?modelos dedesarrollo- y el territorio. Por último un nivel más empíricodonde analizaremos datos de de fuentes secundarias de los CensosEconómicos de 1994 y 2004, buscando relacionar los conceptosdesarrollados en el primer apartado, fortalecer lo analizado en elsegundo y estableciendo tendencias significativas entre dichosperíodos. ","palabras_clave":"MULTINACIONALES|TERRITORIO|CONFLICTO"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":201143,"idioma_id":5,"titulo":"Subprograma Pinus y Pseudotsuga","resumen":"El sector forestal argentino ocupa un lugar destacado en las políticaspúblicas del Ministerio de Agricultura, Ganadería y Pesca de la Nacióntendientes a promover el desarrollo sustentable y con equidad de las economíasregionales, dado el alto potencial de crecimiento de las cadenas yaglomerados forestoindustriales, su proyección para generar una ampliaoferta de bienes y servicios con incorporación de valor agregado -basadoen los saberes y conocimientos locales- y su capacidad de creación deempleos directos e indirectos calificados y no calificados. Por estas razones,el sector fue considerado una parte importante del Plan Estratégico,Agroalimentario y Agroindustrial, Participativo y Federal (PEA) 2020.El trabajo en este sentido requiere estar a la altura de los desafíosque se presentan en el escenario actual. Como resultado de la difusiónmundial de las tecnologías industriales productivas, el nuevo paradigmade las industrias forestales considera que la ventaja competitiva reside,entre otros factores, en la superioridad de la calidad del material de propagaciónque se utiliza.En este marco, la Unidad para el Cambio Rural (UCAR) brinda apoyoa más de 150 proyectos de investigación y experimentación en todoel país, incluyendo el Programa de Mejoramiento de Especies Forestales(PROMEF) que ejecuta el INTA desde 2010, con una inversión deUS$ 1.800.000. Así, el PROMEF es una herramienta que otorga un impulsosustantivo al trabajo desarrollado por el INTA en mejoramientogenético desde la creación del Programa Nacional Forestales, y actúadando continuidad al Programa de Producción de Material de PropagaciónMejorado, ejecutado entre los años 1996 y 2006 con apoyo de laSecretaría de Agricultura, Ganadería y Pesca como parte del Proyecto deDesarrollo Forestal.La disponibilidad de estas herramientas es fruto de una línea de trabajoque mantiene la UCAR desde su creación. En el año 2011, la instituciónconvocó a los principales referentes sectoriales, integrantes deorganismos públicos y organizaciones privadas, tanto del nivel nacionalcomo provincial, quienes se reunieron a lo largo de ocho meses para debatiry elaborar propuestas destinadas al diseño y la implementación deuna política forestal nacional para el siglo XXI.Entre los instrumentos propuestos, se plantearon el apoyo a la innovacióntecnológica -con énfasis en la generación y transferencia de tecnologíassustentables para la producción de madera de calidad- y la conservacióny el uso estratégico de los recursos genéticos, tanto de especiesintroducidas como nativas. De este modo, existió un consenso en quedichos recursos son imprescindibles para cimentar el desarrollo de unabase forestal diversificada y adaptada tanto a las exigencias ecológicas delas diversas regiones productivas de nuestro país como a las necesidadestecnológicas de las industrias forestales.Por eso, en las últimas décadas, los programas de mejoramiento genéticoforestal en la Argentina y en el mundo han pasado a convertirseen un componente esencial a la hora de lograr grandes avances en el aumentode la adaptabilidad y la productividad de los bosques cultivados a través de la selección de los mejores genotipos. Utilizan técnicas y herramientasde última generación y requieren la participación de recursoshumanos especializados, lo que exige un alto nivel de inversión que enla práctica constituye una barrera económica para que los pequeños productorespuedan disponer de material mejorado, reduciendo la productividady la calidad de sus plantaciones que se traduce en una disminuciónde su valor. Dado que en Argentina se estima que hay más de 5.000pequeños productores forestales y rurales con actividades forestales, es elEstado nacional el que desarrolla programas de mejoramiento genéticoque garanticen la disponibilidad de material de calidad a este sector.Esta publicación reúne los resultados de los esfuerzos en este sentidorealizados en los últimos cinco años en el marco del PROMEF, entre losque se destacan la disponibilidad de nuevos materiales de propagaciónen pinos, eucaliptos, sauces y álamos y la implementación de herramientasmoleculares, tanto en los programas de mejoramiento como en laconservación y uso de los recursos genéticos de importantes especies denuestros bosques nativos. Esto no sólo refleja la mejora en la eficienciade los procesos de domesticación y el mejoramiento o en las gananciasgenéticas obtenidas, sino también en la consolidación de recursos humanoscalificados que constituyen un ingrediente único e irremplazablepara contribuir al desarrollo sustentable del sector forestal nacional.","palabras_clave":"Mejoramiento genético"},{"tipo_produccion_id":2,"anio_publica":2017,"producto_id":201167,"idioma_id":5,"titulo":"Mosquitos que crían en cuerpos de agua permanentes (Subfamilia Anophelinae)","resumen":"En 1878, Lynch Arribálzaga publicó la descripción de tres especies de mosquitoscolectados en Argentina, dando inicio a las investigaciones sobre los Culicidae en el país. Años después, en 1891, publicó ?Dipterología Argentina?, convirtiéndose en una referencia para los investigadores que lo sucedieron debido a que les dedicó una gran atención a los mosquitos.","palabras_clave":"no contiene"},{"tipo_produccion_id":3,"anio_publica":2017,"producto_id":202447,"idioma_id":5,"titulo":"Manual De Derecho Laboral 13º Edición","resumen":"MANUAL DERECHO LABORAL","palabras_clave":"Manual|Derecho|Trabajo"},{"tipo_produccion_id":3,"anio_publica":2017,"producto_id":207371,"idioma_id":5,"titulo":"LACLAU Y LO POLÍTICO","resumen":"El libro analiza las principales dimensiones del concepto de 'lo político', tal como aparece tratado en la obra del filósofo y teórico político Ernesto Laclau, a partir de una perspectiva fenomenológico-hermenéutica. Tal indagación encuentra su condición de posibilidad en el abordaje a la vez específico, fenomenológico-hermenéutico y ontológico de lo político sustentado por el propio autor argentino, el cual resulta pasible de un análisis exhaustivo destinado a sistematizar sus aspectos fundamentales, ponderar sus potencialidades y sus déficits teóricos, y confrontarlo con variantes hermenéuticas alternativas. De esta suerte, la lectura holística de la obra laclauniana que aquí se ensaya, se plantea como una exégesis filosófica crítica desplegada desde la reconstrucción de su concepción de lo político a la luz de la hermenéutica heideggeriana que la informa, hasta su desconstrucción y parcial desplazamiento a partir de una óptica inspirada en Lévinas y en Derrida.","palabras_clave":"LACLAU|LO POLÍTICO|ONTOLOGÍA POLÍTICA|HEGEMONÍA|HERMENÉUTICA|FENOMENOLOGÍA"},{"tipo_produccion_id":3,"anio_publica":2017,"producto_id":210402,"idioma_id":5,"titulo":"Política, sociedad, instituciones y saberes. Diálogos interdisciplinares e intercontinentales.","resumen":"Esta compilación es fruto de una serie de actividades realizadas en el año 2011 con motivo de la presencia del Dr. Alain Chatriot, profesor de la Ecole de Hautes Etudes en Sciences Sociales (EHESS) en Argentina. El objetivo del presente libro es difundir no sólo parte de los trabajos discutidos en esa ocasión -que conforman avances de estas nuevas líneas de investigación a nivel local- sino también hacer accesible al público especializado parte de los novedosos desarrollos del Dr. Chatriot, disponibles en su mayoría en francés, y que forman parte de la renovación de los estudios sobre historia política, de las instituciones estatales y las ideas que viene desarrollándose en el seno del mundo académico francés a partir de nombres como Pierre Rosanvallon o Jean Francois Sirinelli -maestros y colegas respectivamente del Dr. Chatriot-.","palabras_clave":"SABERES|POLÍTICA|SOCIEDAD|FRANCIA|ARGENTINA"},{"tipo_produccion_id":3,"anio_publica":2017,"producto_id":214622,"idioma_id":5,"titulo":"El conflicto entre autoridad y autonomía","resumen":"El texto es una edición de mi tesis doctoral que reúne dos capítulos anteriormente publicados de manera independiente y un capítulo inédito a la fecha. El primero presenta la estructura del conflicto entre autoridad y autonomía, el segundo presenta el conflicto desde una concepción voluntarista de la autonomía como autolegilasación (la posición de R.P. Wolff) y el tercero reconstruye y evalúa la respuesta de Raz al desafío del anarquismo: su teoría de la autoridad como servicio.Nota: el libro aun no tiene isbn, puse uno cualquiera para poder cargar la información.","palabras_clave":"autonomía |autoridad|contradicción conceptual"},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":233685,"idioma_id":4,"titulo":"Improving risk stratification of patients with childhood Acute Lymphoblastic Leukemia: Glutathione-S-Transferases polymorphisms are associated with increased risk of relapse","resumen":"The inclusion of genotype at Acute Lymphoblastic Leukemia (ALL) diagnosis as a genetic predictor of disease outcome is under constant study. However, results are inconclusive and seem to be population specific. We analyzed the predictive value of germline polymorphisms for childhood ALL relapse and survival. We retrospectively recruited 140 Argentine patients with de novo ALL. Genotypes were analyzed using PCRRFLP (GSTP1 c.313A > G, MDR1 c.3435T > C, and MTHFR c.665C > T) and multiplex PCR (GSTT1 null, GSTM1 null). Patients with the GSTP1 c.313GG genotype had an increased risk for relapse in univariate (OR = 2.65, 95% CI = 1.03?6.82, p = 0.04) and multivariate (OR = 3.22, 95% CI = 1.17?8.83, p = 0.02) models. The combined genotype slightly increased risk for relapse in the univariate (OR = 2.82, 95% CI = 1.09-7.32, p = 0.03) and multivariate (OR = 2.98, 95% CI = 1.14?7.79, p = 0.03) models for patients with 2\/3-risk-genotypes (GSTT1 null, GSTM1 null, GSTP1 c.313GG). The Recurrence-Free Survival (RFS) was shorter for GSTP1 c.313GG (p = 0.025) and 2\/3-risk-genotypes (p = 0.021). GST polymorphisms increased the risk of relapse and RFS of patients with childhood ALL. The inclusion of these genetic markers in ALL treatment protocols might improve risk stratification and reduce the number of relapses and deaths.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":233742,"idioma_id":4,"titulo":"Supercritical CO2 impregnation of LDPE films with terpene ketones as biopesticides against corn weevil (Sitophilus zeamais)","resumen":"In this work, the supercritical carbon dioxide impregnation of low density polyethylene (LDPE) films with a mixture of two terpenic ketones (thymoquinone and R-(+)-pulegone) with biopesticide activity is investigated, as a strategy for developing a packaging material or delivery device for protecting seeds, kernels and derivatives during storage and transport. Impregnation runs were performed according to a fractional factorial experimental design in order to evaluate the effect of four process variables at two levels (pressure: 10?15 MPa; depressurization rate: 0.5?2.0 MPa\/min; time: 2?4 h; initial ketone mole fraction: 0.0017?0.0025) on impregnation yield and selectivity between ketones. Operational temperature was constant for all experiments and equal to 45 °C. The impregnated films were analyzed by infrared spectroscpy (FTIR) in order to confirm the presence of both ketones and determine their relative ratio in the final product. ANOVA test of the results indicate that contact time and ketone concentration are the only factors with significant effects on impregnation yield (ranging between 2.25 and 5.59%), while no factor seems to affect significantly the loading selectivity, with thymoquinone\/pulegone ratios in the final product between 0.39 and 0.99. The insecticidal activity of impregnated film samples was evaluated in fumigant assays against corn weevil (Sitophilus zeamais Motschulsky), a major pest of stored kernels. The films showed a high activity level during the first 2 days (&#8764;100% mortality), which gradually decreased until showing no toxicity after 7 days.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":233764,"idioma_id":5,"titulo":"OBTENCIÓN  DE  AZÚCARES    FERMENTABLES    A    PARTIR    DE    ASERRÍN    DE    PINO  PRETRATADO SECUENCIALMENTE CON ÁCIDO-BASE","resumen":"El uso de residuos lignocelulósicos constituye una fuente abundante y de bajo costo, que genera, además, una solución al problema de su disposición final. El objetivo del trabajo fue evaluar el efecto de distintas condiciones de pretratamiento secuencial ácido-base de aserrín de pino, sobre la liberación de azúcares reductores en la etapa de sacarificación. El material lignocelulósico se pretrató en dos etapas: la primera, se realizó con ácido sulfúrico (PT1) y la segunda con hidróxido de sodio (PT2), ambas con tres niveles: 1, 2 y 3 % mediante un diseño 32 factorial. La hidrólisis enzimática se realizó a 50 ºC y 150 rpm en frascos de 50 mL. Se tomaron muestras a las 0.15, 24, 48, 72 y 96 h. Se determinó el porcentaje de lignina ácido soluble (% ASL) y la concentración de azúcares reductores. El nivel óptimo de cada factor que favoreció la mayor deslignificación correspondió a 3 % de ácido sulfúrico y 3 % de hidróxido de sodio. La producción de azúcares reductores no se vio afectada por el PT2, pero si por el PT1, alcanzando un máximo para el nivel 0 del mismo (2 % de ácido sulfúrico). Se optimizó el pretratamiento secuencial ácido-base y se comprobó además que éste mejora la hidrólisis enzimática con respecto al aserrín de pino sin pretratar. La cantidad de azúcares reductores obtenidos fue comparable a la obtenida por otros autores.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":233781,"idioma_id":4,"titulo":"Usefulness of Discriminability and Response Bias Indices for the Evaluation of Recognition Memory in Mild Cognitive Impairment and Alzheimer Disease","resumen":"Background: Most studies examining episodic memory in Alzheimer disease (AD) have focused on patients? impaired ability to remember information. This approach provides only a partial picture of memory deficits since other factors involved are not considered. Objective: To evaluate the recognition memory performance by using a yes\/no procedure to examine the effect of discriminability and response bias measures in amnestic mild cognitive impairment (a-MCI), AD dementia, and normal-aging subjects. Methods: We included 43 controls and 45 a-MCI and 51 mild AD dementia patients. Based on the proportions of correct responses (hits) and false alarms from the Rey Auditory Verbal Learning Test (RAVLT), discriminability(d &#8242; ) and response bias (C) indices from signal detection theory (SDT) were calculated. Results: Results showed significant group differences for d &#8242; (F (2) = 83.26, p < 0.001), and C (F (2) = 6.05, p = 0.00). The best predictors of group membership were delayed recall and d &#8242; scores. The d &#8242; measure correctly classified subjects with 82.98% sensitivity and 91.11% specificity. Conclusions: a-MCI and AD dementia subjects exhibit less discrimination accuracy andmore liberal response bias than controls. Furthermore, combined indices of delayed recall and discriminability from the RAVLT are effective in defining early AD. SDT may help enhance diagnostic specificity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":233873,"idioma_id":4,"titulo":"Can 'Caricia' and 'Princesa' apples be considered low-chilling cultivars?","resumen":"The purpose of this work was to study the response of two apple cultivars bred for low chilling environments to artificial chilling accumulation. Two trials were carried out; in experiment one, excised shoots were randomly taken from ?Caricia? and ?Princesa?, and in experiment two, intact and excised shoots of ?Caricia?, ?Princesa? and ?Gala? (control) were collected. After collection, both shoot types were exposed to artificial chilling accumulation (4.0 ± 0.5°C) from 0 to 1200 chill units (CU). Bud break of mixed buds of ?Caricia? and ?Princesa? was higher than 50% between 0 CU to 1200 CU, irrespective of shoot type. Bud break of ?Gala? mixed buds exceeded 50% only in intact shoots afteraccumulating 900 CU. The mean time to bud break of ?Caricia? and ?Princesa? diminished with increasing chilling accumulation and stabilized after ~600 CU, depending on the type of shoot and the year of experimentation. The low-chill apple cultivars tested in this work showed shallow dormancy, but they required moderate cold accumulation (800 ? 1150 CU) to fully satisfy their chilling requirements. Thus, although their shallow dormancy makes them suitable for cultivation in chill-deficient environments, they cannot be considered low-chill cultivars.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234139,"idioma_id":4,"titulo":"Relative sea-level changes during the Holocene in the Rio de la Plata, Argentina and Uruguay: A review","resumen":"This study critically reviews the relative sea-level (RSL) data from the Río de la Plata (RDP)(Argentina and Uruguay) in order to analyze the Holocene RSL changes in this region and thus capture the general trend illustrated by both the data and the high-degree polynomial regression analyses which show good agreement with the ICE-6G_C (VM6) model. The previously inferred Holocene sea-level histories reconstructed from palynological and diatom records from the northern and the southern RDP are also compared to the RSL curves proposed in this work. Analysis of the RSL database revealed that the RSL rose to reach the present level at or before c. 7000 cal yr BP, with the peak of the sea-level highstand c. +4 m between c. 6000 and 5500 cal yr BP (depending on the statistical method used) or at c. 7000 cal yr BP according to the ICE-6G model prediction, gradually falling after this time to the present position. The subaerial data tell a consistent story for the last 6000 years for the RDP but the subsurface data are not in agreement with these data or with the glacial isostatic adjustment (GIA) predictions. Since much of the subaerial data come from shells on beaches, beach ridges and storm beaches, they cannot be strictly interpreted as RSL index points. It seems likely that the predicted curves are somewhat high and could be overestimated. The ?smooth? model of the late Holocene sea-level decline is in close agreement with both the GIA model predictions and the reconstruction of RSL from palynological and diatom records. The models provide no evidence to suggest that there has been a significant trend of change in the speed of sea-level fall or oscillations during the falling stage system tract. The non-parametric regression model, the GIA predictions and the trend inferred by palynological and diatom data trace out a slow sea-level fall for the last c. 6000 cal yr BP. We critically assessed published Holocene sea-level data from the RDP to produce a Holocene RSL curve of sufficient quality to provide a location in this area for testing theoretical models for the Atlantic coast of South America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234216,"idioma_id":4,"titulo":"Influence of the anodizing process variables on the acidic properties of anodic alumina films","resumen":"In the present work, the effect of the different variables involved in the process of aluminum anodizing on the total surface acidity of the samples obtained was studied. Aluminum foils were treated by the electro-chemical process of anodic anodizing within the following variable ranges: concentration=1.5-2.5 M; temperature=303-323 K; voltage=10-20 V; time=30-90 min. The total acidity of the samples was characterized by two different methods: acid-base titration using Hammet indicators and potentiometric titration. The results showed that anodizing time, temperature and concentration were the main variables that determined the surface acid properties of the samples, and to a lesser extent voltage. Acidity increased with increasing concentration of the electrolytic bath, whereas the rest of the variables had the opposite effect. Theresults obtained provide a novel tool for variable selection in order to use synthetized materials as catalytic supports, adding to previous research based on the morphology of alumina layers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234229,"idioma_id":4,"titulo":"Role of Wnt\/&beta;-catenin pathway in the nucleus accumbens in long-term cocaine-induced neuroplasticity: a possible novel target for addiction treatment","resumen":"Cocaine addiction is a chronic relapsing disorder characterized by the loss of control over drug-seeking and taking, and continued drug use regardless of adverse consequences. Despite years of research, effective treatments for psycho-stimulant addiction have not been identified. Persistent vulnerability to relapse arises from a number of long-lasting adaptations in the reward circuitry that mediate the enduring response to the drug. Recently, we reported that the activity of the canonical or Wnt\/&#946;-catenin pathway in the prefrontal cortex (PFC) is very important in the early stages of cocaine-induced neuroadaptations. In the present work, our main goal was to elucidate the relevance of this pathway in cocaine-induced long-term neuroadaptations that may underlie relapse. We found that a cocaine challenge, after a period of abstinence, induced an increase in the activity of the pathway which is revealed as an increase in the total and nuclear levels of &#946;-catenin (final effector of the pathway) in the nucleus accumbens (NAcc), together with a decrease in the activity of glycogen synthase kinase 3&#946; (GSK3&#946;). Moreover, we found that the pharmacological modulation of the activity of the pathway has long-term effects on the cocaine-induced neuroplasticity at behavioral and molecular levels. All the results imply that changes in the Wnt\/&#946;-catenin pathway effectors are long-term neuroadaptations necessary for the behavioral response to cocaine. Even though more research is needed, the present results introduce the Wnt canonical pathway as a possible target to manage cocaine long-term neuroadaptations. (Figure presented.).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234238,"idioma_id":4,"titulo":"Lithocholic acid: a new emergent protector of intestinal calcium absorption under oxidant conditions","resumen":"LCA and 1,25(OH)2D3 are vitamin D receptor ligands with different binding affinity. The secosteroid stimulates the intestinal Ca2+ absorption. Whether LCA alters this process remains unknown. The aim of our work was to know the effect of LCA on intestinal Ca2+ absorption in the absence or presence of NaDOC, bile acid that inhibits the cation transport.  The data show that LCA by itself did not alter the intestinal Ca2+ absorption, but prevented the inhibitory effect of NaDOC. The concomitant administration of LCA avoided the reduction of intestinal alkaline phosphatase activity caused by NaDOC. In addition, LCA blocked a decrease caused by NaDOC on gene and protein expression of molecules involved in the transcellular pathway of intestinal Ca2+ absorption. The oxidative stress and apoptosis triggered by NaDOC were abrogated by LCA co-treatment. In conclusion, LCA placed in the intestinal lumen protects the intestinal Ca2+ absorption against the inhibitory effects caused by NaDOC. LCA avoids the reduction of the transcellular Ca2+ movement apparently by blocking the oxidative stress and apoptosis triggered by NaDOC, normalizing the gene and protein expression of molecules involved in the Ca2+ movement. Therefore, LCA might become a possible treatment to improve intestinal calcium absorption under oxidant conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234272,"idioma_id":4,"titulo":"Sex differences in depolarizing actions of GABA A receptor activation in rat embryonic hypothalamic neurons","resumen":"GABAA receptor activation exerts trophic actions in immature neurons through depolarization of resting membrane potential. The switch to its classical hyperpolarizing role is developmentally regulated. Previous results suggest that a hormonally biased sex difference exists at the onset of the switch in hypothalamic neurons. The aim of this work was to evaluate sex differences in GABAA receptor function of hypothalamic neurons before brain masculinization by gonadal hormones. Hypothalamic cells were obtained from embryonic day 16 male and female rat foetuses, 2 days before the peak of testosterone production by the foetal testis, and grown in vitro for 9 days. Whole-cell and perforated patch-clamp recordings were carried out in order to measure several electrophysiological parameters. Our results show that there are more male than female neurons responding with depolarization to muscimol. Additionally, among cells with depolarizing responses, males have higher and longer lasting responses than females. These results highlight the relevance of differences in neural cell sex irrespective of exposure to sex hormones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234285,"idioma_id":4,"titulo":"An Improved Extended Kalman Filter for Diffuse Optical Tomography","resumen":"In Diffuse Optical Tomography (DOT) the main objective is to estimate the absorp-tion coecent and the reduced scattering coecient of a certain media given a set ofboundary measurements. Biological tissues contains many objects such as arteries, skinand fat whose optical properties are rather dierent than those of the media. Whenthese values are near to those of the background, linear techniques are usually used toestimate them. However, certain objects, such as tumors, may have properties whichcannot be well estimated with linear models. In this article we present a non-linear ap-proach for the Frequency-Domain problem based on an improvement of the ExtendedKalman Filter (EKF) which is used in Estimation-Observation problems, and modi-ed to the DOT parameter estimation problem. The EKF allows to incorporate priorinformation of the measurement noise as well as certain characteristics of the objec-tive media. We show that the proposed methodology is equivalent to existing methodsbut can be applied to other schemes such as Model Reduction as suggested in previousworks. Some computer simulations as well as experimental results are shown to validateour proposal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234287,"idioma_id":4,"titulo":"Mycobacterium tuberculosis multi-drug-resistant strain M induces IL-17+ IFN&#947;- CD4+ T cell expansion through an IL-23 and TGF-&#946;-dependent mechanism in patients with MDR-TB tuberculosis","resumen":"We have reported previously that T cells from patients with multi-drug-resistant tuberculosis (MDR-TB) express high levels of interleukin (IL)-17 in response to the MDR strain M (Haarlem family) of Mycobacterium tuberculosis (M. tuberculosis). Herein, we explore the pathways involved in the induction of Th17 cells in MDR-TB patients and healthy tuberculin reactors [purified protein derivative healthy donors (PPD+ HD)] by the M strain and the laboratory strain H37Rv. Our results show that IL-1&#946; and IL-6 are crucial for the H37Rv and M-induced expansion of IL-17+interferon (IFN)-&#947;- and IL-17+IFN-&#947;+ in CD4+ T cells from MDR-TB and PPD+ HD. IL-23 plays an ambiguous role in T helper type 1 (Th1) and Th17 profiles: alone, IL-23 is responsible for M. tuberculosis-induced IL-17 and IFN-&#947; expression in CD4+ T cells from PPD+ HD whereas, together with transforming growth factor (TGF-&#946;), it promotes IL-17+IFN-&#947;- expansion in MDR-TB. In fact, spontaneous and M. tuberculosis-induced TGF-&#946; secretion is increased in cells from MDR-TB, the M strain being the highest inducer. Interestingly, Toll-like receptor (TLR)-2 signalling mediates the expansion of IL-17+IFN-&#947; cells and the enhancement of latency-associated protein (LAP) expression in CD14+ and CD4+ T cells from MDR-TB, which suggests that the M strain promotes IL-17+IFN-&#947;- T cells through a strong TLR-2-dependent TGF-&#946; production by antigen-presenting cells and CD4+ T cells. Finally, CD4+ T cells from MDR-TB patients infected with MDR Haarlem strains show higher IL-17+IFN-&#947;- and lower IL-17+IFN-&#947;+ levels than LAM-infected patients. The present findings deepen our understanding of the role of IL-17 in MDR-TB and highlight the influence of the genetic background of the infecting M. tuberculosis strain on the ex-vivo Th17 response.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234292,"idioma_id":4,"titulo":"ASSESSMENT OF OCHRATOXIN A OCCURRENCE IN ARGENTINE RED WINES USING A NOVEL SENSITIVE QUECHERS - SOLID PHASE EXTRACTION APPROACH PRIOR TO ULTRA HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY METHODOLOGY","resumen":"BACKGROUND: The assessment of ochratoxin A (OTA) in wine is relevant for food safety and its continuous control allows to reduce the risk of intake. Thus, a novel sensitive QuEChERS-SPE (Quick, Easy, Cheap, Effective, Rugged and Safe ? Solid Phase Extraction) pretreatment prior to liquid chromatography coupled to tandem mass spectrometry was developed for the determination of OTA in red wine samples from different grape-growing regions in Argentine. RESULTS: A sensitive methodology was achieved and thus the limits of detection and quantification were 0.02 and 0.05 µg L&#8722;1, respectively. Recoveries ranged from 89.0% to 105.3%. The method was applied to 136 red wine samples (Argentina´s flagship varieties: Malbec and Cabernet Sauvignon) from ten grape-growing regions, during vintages 2013?2015. Although all of the samples investigated were contaminated with OTA (concentrations ranged from 0.02 to 0.98 µg L&#8722;1), the levels detected were lower than the maximum allowable concentration limit of 2.0 µg L&#8722;1 established by international regulations. CONCLUSION: The methodology proposed is suitable for reliable OTA analysis in red wines. Similarly, the values obtained from the samples analyzed were in accordance with the current regulations and, as a consequence, preventive actions to reduce this mycotoxin incidence can be undertaken. © 2016 Society of Chemical Industry.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234302,"idioma_id":4,"titulo":"Three symbionts involved in interspecific plant-soil feedback: Epichloid endophytes and mycorrhizal fungi affect the performance of rhizobia-legume symbiosis","resumen":"Aims: Plants interact by modifying soil conditions in plant-soil feedback processes. Foliar endophytes of grasses exert multiple effects on host rhizosphere with potential consequences on plant-soil feedback. Here, we hypothesize that the grass-endophyte symbiosis impairs soil symbiotic potential, and in turn influences legume performance and nitrogen acquisition. Methods: Soil was conditioned in pots, growing Lolium multiflorum with or without the fungal endophyte Epichloë and with or without arbuscular mycorrhizal fungi (AMF). Then, Trifolium repens grew in all types of conditioned soils with high or low rhizobia availability. Results: Endophyte soil conditioning reduced AMF spores number and rhizobial nodules (-27% and -38%, respectively). Seedling survival was lower in endophyte-conditioned soil and higher in mycorrhizal soils (-27 % and +24%, respectively). High rhizobia-availability allowed greatergrowth and nitrogen acquisition, independent of soil conditioning. Low rhizobia-availability allowed both effects only in endophyte-conditioned soil.Conclusion: Endophyte-induced changes in soil (i) hindered symbionts potential by impairing AMF spores availability or rhizobia nodulation, (ii) impaired legume survival irrespective of belowground symbionts presence, but (iii) mimicked rhizobia effects, enhancing growth and nitrogen fixation in poorly nodulated plants. Our results show that shoot and root symbionts can be interactively involved in interspecific plant-soil feedbacks.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234303,"idioma_id":4,"titulo":"Bioactive glasses as delivery systems for antimicrobial agents IF: 2.16","resumen":"Most biomaterial-associated infections are caused by opportunistic pathogens and bacteria that are regularly found within the microflora of the implant site. In addition, a biomaterial implant or device remains at risk of infection by hematogenous spread of bacteria disseminated from infections elsewhere in the body or from infected peri-implant tissue in revision surgery. The resulting infections are frequently accompanied by patient morbidity and discomfort and can lead to surgical replacement of the implant after lengthy, unsuccessful attempts to mitigate infections with antibiotic treatments. Therefore, extensive is aiming to find new infection-resistant antimicrobial biomaterials and coatings for implants and devices to effectively reduce the incidence of biomaterial-associated infections. An overview of the in vitro and in vivo antimicrobial efficacies of the numerous biomaterials currently available is beyond the scope of this review. Herein, we provide a comprehensive review of bioactive glasses as biomaterial delivery systems for antimicrobial agents.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234323,"idioma_id":5,"titulo":"El ensamble de micromamíferos del Parque Nacional Bosques Petrificados de Jaramillo, provincia de Santa Cruz, Argentina","resumen":"RESUMEN. El Parque Nacional Bosques Petrificados de Jaramillo (PNBPJ), situado en la provincia de Santa Cruz, es un área silvestre destinada a la protección de la Estepa Patagónica, una de las ecorregiones más vulnerables y de máxima prioridad de conservación. Estudiamos la composición específica, abundancia relativa, riqueza y diversidad de los micromamíferos del PNBPJ, pobremente documentada hasta el momento. Durante marzo de 2010, 2011, 2012 y 2013 realizamos capturas en los ambientes más representativos del PNBPJ (cañadones,estepa arbustiva y estepa subarbustiva); y presentamos los resultados del análisis de egagrópilas de Tyto alba y Bubo magellanicus recolectadas ocasionalmente entre los meses de enero y abril de 2002, 2004 y 2009en el área protegida. Identificamos un total de 10 especies de micromamíferos: Lestodelphys halli, Abrothrix olivacea, Eligmodontia morgani, Notiomys edwardsii, Graomys griseoflavus, Phyllotis xanthopygus, Reithrodonauritus, Euneomys chinchilloides, Microcavia australis, y Ctenomys magellanicus. La especie más abundante en las capturas fue Eligmodontia morgani (67.55%) y no existieron diferencias significativas en las abundancias de las distintas especies entre los tres ambientes muestreados. La estepa subarbustiva presentó unos valores de riqueza y diversidad específica ligeramente inferiores a los de los otros dos ambientes, cuyos valores fueron muy similares entre sí. Nuestros resultados concuerdan con lo esperado para ensambles de micromamíferos de áreasno protegidas asociados con el Macizo del Deseado y el valle del río Deseado, donde se localiza el PNBPJ. Se discuten las características del ensamble del PNBPJ desde el punto de vista eco-geográfico, y se comparan con ensambles similares situados en la misma latitud.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234364,"idioma_id":4,"titulo":"Triolein reduces MMP-1 upregulation in dermal fibroblasts generated by ROS production in UVB-irradiated keratinocytes","resumen":"Background Cytokine production and oxidative stress generated by ultraviolet radiation B (UVB) skin exposure are main factors of skin photoaging. Interleukin-6 (IL-6) produced by irradiated keratinocytes is proposed to have a role in metalloproteinases (MMPs) expression activation in dermal fibroblasts. Objectives We examined the effect of triolein treatment of UVB-irradiated keratinocytes on MMP1 (interstitial collagenase) expression response of dermal fibroblasts. We assayed UVB-irradiated keratinocytes soluble signals, mainly IL-6 and reactive oxygen species (ROS). Methods IL-6 expression and ROS generation were assayed in UVB-irradiated keratinocytes. MMP1 mRNA expression response was assayed in fibroblasts grown in keratinocytes conditioned medium. We evaluated the effect of treating keratinocytes with triolein on IL-6 expression and ROS generation in keratinocytes, and MMP1 expression in fibroblasts. Results The irradiation of epidermal cells with sublethal UVB doses increased IL-6 expression and ROS generation. Conditioned culture medium collected from keratinocytes was used to culture dermal fibroblasts. MMP1 mRNA expression increase was observed in fibroblasts cultured in medium collected from UVB-irradiated keratinocytes. Triolein treatment reduced the IL-6 expression and ROS generation in keratinocytes and this effect was reflected in downregulation of MMP1 expression in fibroblasts. Conclusions Triolein reduces both the expression of IL-6 and ROS generation in irradiated keratinocytes. It seems to exert an anti-inflammatory and anti-oxidative stress effect on irradiated keratinocytes that in turn reduces MMP1 expression in dermal fibroblasts. Collectively, these results indicate that triolein could act as a photoprotective agent.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234370,"idioma_id":4,"titulo":"Noninfectious complications in patients with pediatric-onset common variable immunodeficiency correlated with defects in somatic hypermutation but not in class-switch recombination","resumen":"BACKGROUND:Common variable immunodeficiency (CVID) is a heterogeneous syndrome characterized by impaired immunoglobulin production and usually presents with a normal quantity of peripheral B cells. Most attempts aiming to classify these patients have mainly been focused on T- or B-cell phenotypes and their ability to produce protective antibodies, but it is still a major challenge to find a suitable classification that includes the clinical and immunologic heterogeneity of these patients.OBJECTIVE:In this study we evaluated the late stages of B-cell differentiation in a heterogeneous population of patients with pediatric-onset CVID to clinically correlate and assess their ability to perform somatic hypermutation (SHM), class-switch recombination (CSR), or both.METHODS:We performed a previously reported assay, the restriction enzyme hotspot mutation assay (Ig&#954;REHMA), to evaluate in vivo SHM status. We amplified switch regions from genomic DNA to investigate the quality of the double-strand break repairs in the class-switch recombination process in vivo. We also tested the ability to generate immunoglobulin germline and circle transcripts and to upregulate the activation-induced cytidine deaminase gene through in vitro T-dependent and T-independent stimuli.RESULTS:Our results showed that patients could be classified into 2 groups according to their degree of SHM alteration. This stratification showed a significant association between patients of group A, severe alteration, and the presence of noninfectious complications. Additionally, 60% of patients presented with increased microhomology use at switched regions. In vitro activation revealed that patients with CVID behaved heterogeneously in terms of responsiveness to T-dependent stimuli.CONCLUSIONS:The correlation between noninfectious complications and SHM could be an important tool for physicians to further characterize patients with CVID. This categorization would help to improve elucidation of the complex mechanisms involved in B-cell differentiation pathways.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234386,"idioma_id":4,"titulo":"Manchette-Acrosome Disorders During Spermiogenesis and Low Efficiency of Seminiferous Tubules in Hypercholesterolemic Rabbit Model","resumen":"Hypercholesterolemia is a marker for several adult chronic diseases. Recently we demonstratedthat sub\/infertility is also associated to Hypercholesterolemia in rabbits. Seminalalterations included: abnormal sperm morphology, decreased sperm number and declinedpercentage of motile sperm, among others. In this work, our objective was to evaluate theeffects of hypercholesterolemia on testicular efficiency and spermiogenesis, as the latterare directly related to sperm number and morphology respectively. Tubular efficiency wasdetermined by comparing total number of spermatogenic cells with each cell type within theproliferation\/differentiation compartments. We found lower testicular efficiency related toboth a decrease in spermatogonial cells and an increase in germ cell apoptosis in hypercholesterolemicrabbits. On the other hand, spermiogenesis±the last step of spermatogenesisinvolved in sperm shaping±was detaily analyzed, particularly the acrosome-nucleusmanchettecomplex. The manchette is a microtubular-based temporary structure responsiblein sperm cell elongation. We analyzed the contribution of actin filaments and raftmicrodomains in the arrangement of the manchette. Under fluorescence microscopy, spermatocyteto sperm cell development was followed in cells isolated from V to VIII tubularstages. In cells from hypercholesterolemic rabbits, abnormal development of acrosome,nucleus and inaccurate tail implantation were associated with actin±alpha-tubulin±GM1sphingolipid altered distribution. Morphological alterations were also observed at electronmicroscopy. We demonstrated for the first time that GM1-enriched microdomains togetherwith actin filaments and microtubules are involved in allowing the correct anchoring ofthe manchette complex. In conclusion, cholesterol enriched diets promote male fertilityalterations by affecting critical steps in sperm development: spermatogenesis and spermiogenesis. It was also demonstrated that hypercholesterolemic rabbit model is a usefultool to study serum cholesterol increment linked to sub\/infertility.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234389,"idioma_id":4,"titulo":"Rational design of nitrofuran derivatives: Synthesis and valuation as inhibitors of Trypanosoma cruzi trypanothione reductase","resumen":"The rational design and synthesis of a series of 5-nitro-2-furoic acid analogues are presented. The trypanocidal activity against epimastigote forms of Trypanosoma cruzi and the toxic effects on human HeLa cells were tested. Between all synthetic compounds, three of thirteen had an IC50 value in the range of Nfx, but compound 13 exhibited an improved effect with an IC50 of 1.0&nbsp;±&nbsp;0.1&nbsp;&#956;M and a selective index of 70 in its toxicity against HeLa cells. We analyzed the activity of compounds 8, 12 and 13 to interfere in the central redox metabolic pathway in trypanosomatids, which is dependent of reduced trypanothione as the major pivotal thiol. The three compounds behaved as better inhibitors of trypanothione reductase than Nfx (Ki values of 118&nbsp;&#956;M, 61&nbsp;&#956;M and 68&nbsp;&#956;M for 8, 12 and 13, respectively, compared with 245&nbsp;&#956;M for Nfx), all following an uncompetitive enzyme inhibition pattern. Docking analysis predicted a binding of inhibitors to the enzyme-substrate complex with binding energy calculated in-silico that supports such molecular interaction.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234403,"idioma_id":4,"titulo":"Apomixis Frequency under Stress Conditions in Weeping Lovegrass (Eragrostis curvula)","resumen":"To overcome environmental stress, plants develop physiological responses that are triggered by genetic or epigenetic changes, some of which involve DNA methylation. It has been proposed that apomixis, the formation of asexual seeds without meiosis, occurs through the temporal or spatial deregulation of the sexual process mediated by genetic and epigenetic factors influenced by the environment. Here, we explored whether there was a link between the occurrence of apomixis and various factors that generate stress, including drought stress, in vitro culture, and intraspecific hybridization. For this purpose, we monitored the embryo sacs of different weeping lovegrass (Eragrostis curvula [Schrad.] Nees) genotypes after the plants were subjected to these stress conditions. Progeny tests based on molecular markers and genome methylation status were analyzed following the stress treatment. When grown in the greenhouse, the cultivar Tanganyika INTA generated less than 2% of its progeny by sexual reproduction. Plants of this cultivar subjected to differentstresses showed an increase of sexual embryo sacs, demonstrating an increased expression of sexuality compared to control plants. Plants of the cv. Tanganyika USDA did not demonstrate the ability to generate sexual embryo sacs under any conditions and is therefore classified as a fully apomictic cultivar. We found that this change in the prevalence of sexuality was correlated with genetic and epigenetic changes analyzed by MSAP and AFLPs profiles. Our results demonstrate that different stress conditions can alter the expression of sexual reproduction in facultative tetraploid apomictic cultivars and when the stress stops the reproductive mode shift back to the apomixis original level. These data togetherwith previous observations allow us to generate a hypothetical model of the regulation of apomixis in weeping lovegrass in which the genetic\/s region\/s that condition apomixis, is\/are affected by ploidy, and is\/are subjected to epigenetic control.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234419,"idioma_id":4,"titulo":"Quaternary deformation and stress field in the Río de la Plata Craton (Southeastern South America)","resumen":"The aim of this research was to analyse the deformation in an intraplate region of southeastern South America. We analysed the motion velocities of GNSS permanent stations to characterise the stress field in the Río de la Plata Craton (RPC). To this end, a multi-year solution of the SIRGAS-CON continuous monitoring geodetic network was analysed. Seven stations in the cratonic region in the Pampean flat-slab subduction latitudes were considered. The solution encompasses the weekly solutions from January 2000 up to one day before the Maule earthquake on February 26th, 2010. The GNSS stations that produce significant results are located in Argentine territory and have a time span of at least 2 years. The stresses inferred from the strain rate tensors obtained from triangle arrays and relative displacement velocities between stations (baselines) suggest a compressive \/ transpressive regimen in the central-western RPC. On the basis of the GNSS velocity field, we can estimate maximum compression axes ranging from 3.5 to 5.3 nano-strain with W-E trends (90.3°-93.8°E), which differs slightly from the convergence vector between the Nazca and South American plates (ENE\/78°E). This result strongly suggests the influence on the South America mid-plate from far-field stresses generated in the plate margins and the rotation of the maximum compression axes due to the growing influence eastward from the Mid-Atlantic ridge push. Satellite gravimetric data allow us to interpret the presence of upper crustal structures, which match surface morphostructural features. It is reasonable to think that the structures concentrate the recent deformation. The geometry of the subsurface structures inferred appears to favour reverse slips, compatible with the stress field interpreted from geodetic data. Regional wetland layers interpreted to be planar geomorphic markers, currently situated at elevations higher than the maximum sea levels reached over the Quaternary, can be interpreted as evidence of deformation and regional uplift. The compressive stresses appear to have substantial control over the uplift in the wide lowland areas of the Chaco-Parana intracratonic basin. The geomorphologic analysis suggests lineal uplift rates from 0.025 to 0.050 mm.yr-1 for the central RPC in the Quaternary time scale and 0.1 to 0.35 mm.yr-1 for the western RPC in the Late Pleistocene time scale.Although geodetic data are not conclusive evidence of seismic hazards, the confluence of geodetic and geologic data allows us to presume that deformation energy is being accumulated in the main fault systems.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234422,"idioma_id":4,"titulo":"Adding recognition discriminability index to the delayed recall is useful to predict conversion from mild cognitive impairment to Alzheimer's disease in the alzheimer's disease neuroimaging initiative","resumen":"Background: Ongoing research is focusing on the identification of those individuals with mild cognitive impairment (MCI) who are most likely to convert to Alzheimer´s disease (AD). We investigated whether recognition memory tasks in combination with delayed recall measure of episodic memory and CSF biomarkers can predict MCI to AD conversion at 24-month follow-up. Methods: A total of 397 amnestic-MCI subjects from Alzheimer´s disease Neuroimaging Initiative were included. Logistic regression modeling was done to assess the predictive value of all RAVLT measures, risk factors such as age, sex, education, APOE genotype, and CSF biomarkers for progression to AD. Estimating adjusted odds ratios was used to determine which variables would produce an optimal predictive model, and whether adding tests of interaction between the RAVLT Delayed Recall and recognition measures (traditional score and d-prime) would improve prediction of the conversion from a-MCI to AD. Results: 112 (28.2%) subjects developed dementia and 285 (71.8%) subjects did not. Of the all included variables, CSF A&#946;1-42 levels, RAVLT Delayed Recall, and the combination of RAVLT Delayed Recall and d-prime were predictive of progression to AD (&#967;2 = 38.23, df = 14, p < 0.001). Conclusions: The combination of RAVLT Delayed Recall and d-prime measures may be predictor of conversion from MCI to AD in the ADNI cohort, especially in combination with amyloid biomarkers. A predictive model to help identify individuals at-risk for dementia should include not only traditional episodic memory measures (delayed recall or recognition), but also additional variables (d-prime) that allow the homogenization of the assessment procedures in the diagnosis of MCI.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234423,"idioma_id":4,"titulo":"Intrafamilial variable phenotype including corticobasal syndrome in a family with p.P301L mutation in the MAPT gene: first report in South America","resumen":"FTD is a neuropathological disorder that causes a variety of clinical syndromes including FTdementia, progressive supranuclear palsy , and corticobasal syndrome. FTD associated with parkinsonism occurs frequently as result ofd mutations in the C9orf72 gene and also in the gene coding for the protein associated with microtubule tau (MAPT) and progranulin (GRN) on chromosome 17. Herein we report an Argentinean family of Basque ancestry with an extensive family history of behavioral variant of FTD with the p.P301L-MAPT mutation, the first in south america.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234424,"idioma_id":4,"titulo":"The role of GABAA in the expression of updated information through the reconsolidation process in humans","resumen":"Consolidated memory can be again destabilized by the presentation of a memory cue (reminder) of the previously acquired information. During this process of labilization\/restabilization memory traces can be either impaired, strengthened or updated in content. Here, we study if a consolidated memory can be updated by linking one original cue to two different outcomes and whether this process was modulated by the GABAergic system. To aim that, we designed two experiments carried out in three consecutive days. All participants learned a list of non-sense syllable pairs on day 1. On day 2 the new information was introduced after the reminder or no-reminder presentation. Participants were tested on day 3 for the updated or original list (Exp. 1). In Exp. 2 we tested whether this new information was incorporated by an inhibitory process mediated by the GABAergic system. For that, participants retrieved the original information before being taken Clonazepam 0.25 mg (GABAA agonist) or Placebo pill. We found that the groups that received the reminder correctly recalled the old and new information. However, the no reminder groups only correctly recalled the original information. Furthermore, when testing occurred in the presence of Clonazepam, the group that received the reminder plus the new information showed an impaired original memory performance compared to the group that received only Clonazepam (without reminder) or the reminder plus Placebo pill. These results show that new information can be added to a reactivated declarative memory in humans by linking one cue to two different outcomes. Furthermore, we shed light on the mechanisms of memory updating being the GABAergic system involved in the modulation of the old and new information expression.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234442,"idioma_id":5,"titulo":"DE LA PRODUCCIÓN AL USO: TECNOLOGÍA DE HOJAS EN EL SITIO CUEVA MARIPE (SANTA CRUZ, ARGENTINA)","resumen":"La tecnología de hojas ha sido reconocida en varias localidades arqueológicas de Patagonia, principalmente en contextos del Holoceno Medio y Tardío. Numerosos autores han afrontado el estudio de estas tecnologías entendiéndolas como formas de aprovechamiento de materias primas tendiente a la optimización. Sin embargo, la producción y uso de hojas muchas veces implica otras decisiones más allá de la disponibilidad de materias primas en un área determinada. En el sitio Cueva Maripe (provincia de Santa Cruz, Argentina) fueron registrados artefactos correspondientes a la totalidad de la cadena operativa de la producción de hojas. Por lo tanto, el siguiente trabajo tiene por objetivo analizar las evidencias de los distintos pasos en la manufactura de esta tecnología durante el lapso ocupacional del Holoceno Medio, desde la preparación del núcleo hasta su uso y descarte. Dado que a lo largo del Macizo del Deseado abundan rocas de buena calidad para la talla, la producción de hojas en Cueva Maripe no estaría dirigida hacia una estrategia de maximización de materias primas. Los resultados obtenidos del análisis tecnomorfológico y funcional permiten sostener que la confección de dichas piezas estaría relacionada con un determinado modo de producción y con diseños orientados a una multiplicidad de usos (trabajo sobre material blando, madera y hueso).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":234975,"idioma_id":5,"titulo":"ARCILLAS ESMECTÍTICAS DE LA REGIÓN NORPATAGÓNICA ARGENTINA COMO BARRERAS HIDRÁULICAS DE RELLENOS SANITARIOS Y AGENTES DE RETENCIÓN DE METALES PESADOS","resumen":"La principal preocupación en los rellenos sanitarios es la posible migración de lixiviadoy eventual contaminación del agua subterránea. Esta migración se controlainterponiendo barreras constituidas por capas de arcilla compactadas que poseen bajaconductividad hidráulica y alta capacidad de retención de contaminantes. El objetivode este estudio fue evaluar la conductividad hidráulica y la capacidad de retenciónde metales pesados de dos arcillas esmectíticas con el fin de determinar sus aptitudescomo barreras hidráulicas y geoquímicas de rellenos sanitarios. Se realizaron ensayosde conductividad hidráulica de mezclas arcilla-arena con agua destilada y un lixiviadoreal de residuossólidos urbanos como fluidos permeantes.Adicionalmente,se realizaronensayos de adsorción en lotes a partir de soluciones monometálicas de Cu(II), Zn(II),Ni(II) y Cd(II). La conductividad hidráulica determinada con lixiviado fue entre unoy tres órdenes de magnitud mayor en relación con el agua, debido principalmente ala elevada salinidad de dicho lixiviado, lo que contribuye a generar un estado masfloculado de las arcillas y a la desaparición de fases minerales solubles. Los datos deadsorción de los metales estudiados sobre las arcillas se ajustaron a la isoterma deLangmuir. La capacidad de adsorción de los metales analizados fue en el orden: Zn(II)> Cu(II) > Ni(II) > Cd(II) para la bentonita CATAE y Zn(II) > Ni(II) > Cu(II) > Cd(II)para la fangolita NTOL. La capacidad de adsorción de Cu(II) y Zn(II) fue superior a lacapacidad de intercambio catiónico de las arcillas, mientras que para Cd(II) y Ni(II),la cantidad retenida no supera este valor. Por otro lado, la conductividad hidráulicade las mezclas arcilla-arena fue menor a 1 x 10-9 m\/s. En función de estos resultados,las arcillas analizadas muestran una aptitud adecuada para ser usadas como barrerashidráulicas y geoquímicas de rellenos sanitarios de acuerdo con lo estipulado en lalegislación internacional para barreras arcillosas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":235132,"idioma_id":4,"titulo":"Evaluation of nickel and copper catalysts in biogas reforming for SOFC","resumen":"The solid oxide fuel cells (SOFC) enable the efficient generation of clean energy, fitting the current requirementsof the growing demand for electricity and for the environment preservation. When powered with biogas(from digesters of municipal wastes), the SOFCs also contribute to reduce the environmental impact of thesewastes. The most suitable route to produce hydrogen inside SOFC from biogas is through dry reforming butthe catalyst is easily deactivated by coke, because of the high amounts of carbon in the stream. A promisingway to overcome this drawback is by adding a second metal to nickel-based catalysts. Aiming to obtain active,selective and stable catalysts for biogas dry reforming, solids based on nickel (15%) and copper (5%) supportedon aluminum and magnesium oxide were studied in this work. Samples were prepared by impregnating thesupport with nickel and copper nitrate, followed by calcination at 500, 600 and 800 ºC. It was noted that allsolids were made of nickel oxide, nickel aluminate and magnesium aluminate but no copper compound wasfound. The specific surface areas did not changed with calcination temperature but the nickel oxide averageparticles size increased. The solids reducibility decreased with increasing temperature. All catalysts were activein methane dry reforming, leading to similar conversions but different selectivities to hydrogen and differentactivities in water gas shift reaction (WGSR). This behavior was assigned to different interactions betweennickel and copper, at different calcination temperatures. All catalysts were active in WGSR, decreasing thehydrogen to carbon monoxide molar ratio and producing water. The catalyst calcined at 500 oC was the mostpromising one, leading to the highest hydrogen yield, besides the advantage of being produced at the lowestcalcination temperature, requiring less energy in its preparation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":235367,"idioma_id":4,"titulo":"Transcriptional regulation of the protein kinase A subunits  in Saccharomyces cerevisiae during fermentative growth","resumen":"Yeast cells can adapt their growth in response to the nutritional environment. Glucose isthe favourite carbon source of Saccharomyces cerevisiae, which prefers a fermentativemetabolism despite the presence of oxygen. When glucose is consumed, the cell switchesto the aerobic metabolism of ethanol, during the so-called diauxic shift. The differencebetween fermentative and aerobic growth is in part mediated by a regulatory mechanismcalled glucose repression. During glucose derepression a profound gene transcriptionalreprogramming occurs and genes involved in the utilization of alternative carbonsources are expressed. Protein kinase A (PKA) controls different physiological responsesfollowing the increment of cAMP as a consequence of a particular stimulus. cAMP?PKAis one of the major pathways involved in the transduction of glucose signalling. In thiswork the regulation of the promoters of the PKA subunits during respiratory and fermentativemetabolism are studied. It is demonstrated that all these promoters are upregulatedin the presence of glycerol as carbon source through the Snf1\/Cat8 pathway.However, in the presence of glucose as carbon source, the regulation of each PKA promotersubunits is different and only TPK1 is repressed by the complex Hxk2\/Mig1 inthe presence of active Snf1.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238072,"idioma_id":5,"titulo":"Minerales con hierro en arcillas vinculadas a la ingresión marina holocena en la llanura costera del estuario del río de la plata (argentina): implicancias paleoambientales","resumen":"En este trabajo se efectúa la caracterización de los minerales portadores de hierroen arcillas de la llanura costera del estuario del Río de la Plata, incluidas en laFacies Villa Elisa de la Formación Las Escobas (MIS1), con el principal objetivode contribuir a su interpretación paleoambiental. Además, los resultados permitenhacer inferencias que se estiman de interés para la Pedología y para lasCiencias Ambientales. El trabajo abarca el uso de diversas técnicas (análisis químicos,determinación de propiedades magnéticas, análisis térmico diferencialtermogravimétrico,difractometría de rayos X y espectroscopia Mössbauer). Losmateriales analizados presentan tonalidades gris-oliva y se clasifican como arcillas.Presentan una asociación mineralógica compleja, resultado de la combinación demúltiples factores, que incluyen procesos vinculados a su procedencia, al ambientede depositación y a los efectos de la pedogénesis. Dominan los argilominerales(aproximadamente 60%), representados principalmente por esmectitas, illita ysecundariamente por caolinita e interestratificados illita\/esmectita con elevadocontenido de capas expansivas. Se identificó también la presencia de cuarzo, plagioclasas,feldespatos alcalinos y en menor medida calcita y óxi-hidróxidos de hierro.El contenido de hierro total es considerable (alrededor del 10%), con un claro predominiode Fe3+ sobre el Fe2+ (92% y 8%, respectivamente). Los óxi-hidróxidosde hierro presentes (goethita y eventualmente ferrihidrita) no constituyen losprincipales portadores de hierro. De esta manera se concluye que el Fe3+ se encuentraprincipalmente en los argilominerales, en particular en esmectitas ricasen hierro (Fe-esmectitas), del tipo nontronita\/Fe-beidellita. La asociación mineraldeterminada tiene importantes implicancias para la interpretación paleoambiental.Se concluye que un ambiente de marisma recibió argilominerales a partir de laerosión de suelos loéssicos (principalmente esmectitas e illita) y por corrientesmareales (más ricos en esmectitas y caolinita). Mecanismos propios del ambientedepositacional, vinculados a ciclos de humedecimiento-secado con oscilaciones de Eh en un medio levemente alcalino permitieron la incorporación de hierro enla estructura de las esmectitas. Un aspecto a destacar es que estos materiales presentancolores glei originados por minerales con Fe3+ (Fe-esmectitas y goethita),lo cual contradice el tradicional supuesto en Pedología, que asocia este patrón decolor a minerales de Fe2+. Finalmente, se destaca que la elevada participación deFe-esmectitas en asociación con óxi-hidróxidos de hierro, contribuye a la adsorciónde metales pesados y otros contaminantes de la región, dándole a la Facies VillaElisa un importante valor ambiental.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238073,"idioma_id":5,"titulo":"Consumo de alcohol en ratas adolescentes tratadas con reserpina y fluoxetina-MP-","resumen":"Si bien se ha estudiado el vínculo entre los trastornos de estado de ánimo y el consumo de alcohol, tanto en humanos como en animales, todavía no es del todo claro cómo se da esta relación, y menos aún durante la adolescencia. La administración de reserpina, un depletor de monoaminas, es un modelo ampliamente utilizado en roedores adultos para inducir comportamientos asociados a depresión, pero se desconoce su utilidad en otras etapas del desarrollo. En este trabajo validamos este modelo en ratas adolescentes y posteriormente estudiamos el consumo de alcohol en estos animales, así como su modulación por antidepresivos. En el experimento 1 se administró reserpina (0.0 o 1.0 mg\/kg, durante 4 días, IP) a ratas Wistar machos de 30 días. El consumo de alcohol fue evaluado luego de observar comportamientos asociados a depresión e indagar indicadores neuroendocrinos de esta patología. En el experimento 2 los animales recibieron reserpina, seguida por el antidepresivo fluoxetina (0.0 o 10.0 mg\/kg, durante 4 días, IG), y luego se evaluó el consumo de alcohol. Los resultados mostraron que la reserpina aumentó significativamente los comportamientos asociados a depresión y alteró los niveles de dopamina en la corteza insular y de hormonas tiroideas en sangre. En la prueba de consumo de alcohol los animales deprimidos, pero no los controles, mostraron un incremento en el consumo a través de los días. El segundo experimento replicó parcialmente este perfil, y no se observó un efecto significativo del antidepresivo en el consumo de alcohol. Los resultados indican que la reserpina es útil para modelar en ratas adolescentes comportamientos asociados a depresión. Se encontró una relación entre este estado y el consumo de alcohol, que no se pudo revertir con antidepresivos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238074,"idioma_id":5,"titulo":"La crítica de lo indecible. Sobre La poesía, reino autónomo, de Roberto Fernández Retamar.-MP-","resumen":"Artículo crítico sobre la edición argentina de La poesía, reino autónomo (2016), de Roberto Fernández Retamar -que amplía la cubana (2000)-, recopilación de casi toda su producción crítica y ensayística sobre poesía y poetas iberoamericanos. Se realiza una valoración de su trayectoria crítica, especialmente de su participación como crítico y poeta de la llamada poesía conversacional hispanoamericana. A tenor con el contexto inicial de la Revolución cubana, de la emergencia de la norma conversacional y de su apuesta por la construcción de una teoría literaria latinoamericana, se polemiza con algunas de sus ideas, o se matizan otras. Se reconocen muchos de sus aportes cognitivos. Se destaca la presencia de la literatura argentina, sobre todo de Borges, en su pensamiento poético. Se trata de caracterizar la índole de su estilo (de su prosa) como crítico y ensayista; la singularidad de su mirada; algunas de sus fuentes y afinidades tanto ideológicas como literarias, así como sus estrategias de (auto)legitimación de la poesía hispanoamericana. Se destaca su etapa formativa en el ámbito del grupo Orígenes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238075,"idioma_id":4,"titulo":"Reply to ?Comment on population trends of southern rockhopper penguins (Eudyptes chrysocome chrysocome) on Isla Pingu&#776;ino, Santa Cruz, Argentina? by Nina Dehnhard","resumen":"Recently N. Dehnhard has commented on our paper publishedin Polar Biology (Gandini et al. 2016). She noted outseveral points of criticism on the interpretation and conclusionof our results, particularly our hypothesis presented inthe discussion stating that the population increase observedat Isla Pingu&#776;ino colony (IP) could not be obtained by intrinsicgrowth but was likely driven by immigration?probablyfrom the Falkland Islands\/Islas Malvinas (hereafter FI-M).The objective of this reply is to respond to the most importantcriticisms, but not first thanking for her willingness toimprove our work. The main objective of our study (Gandiniet al. 2016) was to determine whether the populationat IP has continued to grow since its discovery assessingits population trend over a 30-year period. We also estimatedthe breeding success of this species at this site. Thenotion of a potential immigration from FI-M to IP was ahypothesis, and as we clearly affirmed, ?further studies,including genetic comparisons, are needed to confirm theimmigration hypothesis?. To respond to the main pointsdiscussed by Dehnhard, we will follow the same order asher comments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238076,"idioma_id":4,"titulo":"Role of inbreeding depression, non -inbred dominance deviations and random year-season effect in genetic trends for prolificacy in closed rabbit lines-MP-","resumen":"In closed rabbit lines selected for prolificacy at the Polytechnic University ofValencia, genetic response predicted using BLUP is biased compared to the response measured utilizing a control population. In these lines, there is aconfusion between genetic trend, year-season effects and inbreeding, and therole of dominance is uncertain. This is a common situation in data fromreproductively closed selection lines. This paper fits different genetic evaluation models to data of these lines, aiming to identify the source of these biases:dominance, inbreeding depression, and\/or an ill conditioned model due to the strong collinearity between year-season and inbreeding. The study involvedthree maternal lines (A, V and H), and analyzed two traits, total born (TB) andnumber of kits at weaning (NW). Models fitting year-season effect as fixed orrandom were implemented, in addition to additive genetic, permanent and non-inbred dominance deviations effects. When year-season was fitted as a fixedeffect, the genetic trends were overestimated compared to responses estimatedusing control populations obtained from frozen embryos, inbreeding had anapparent positive effect, and the environmental trends were negative. Whenyear-season was fitted as random, the genetic trends were compatible withcontrol populations results, inbreeding had a negative effect (lower prolificacy), and environmental trends were flat. The model fitting random year-season, inbreeding, and non-inbred dominance deviations yielded the following ratios of additive and dominance variances to total variance for NW: 0.06 and 0.01 for line A, 0.06 and 0.00 for line V, and 0.01 and 0.08 for line H. Except for line H,dominance deviations seem to be of low relevance. When it is confounded with inbreeding as in these lines, fitting year-season effect as random allows correct estimate of genetic trends.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238077,"idioma_id":4,"titulo":"An application of the augmented &epsilon;-constraint method to design a municipal sorted waste collection system","resumen":"The separation at the source of Municipal Solid Waste (MSW) is an initiative that facilitates the subsequent recycling work and contributes to palliate the negative impacts of the traditional unsorted collection system. This paper presents a multi-objective integer linear programming model of the determination of the optimal location of assorted waste bins in an urban area. We consider, jointly, the objectives of minimizing the investment cost and the average distance from the dwellings to the bins. The model was applied in simulated instances of an Argentinian medium-size city, contributing to the transition from the current door-to-door based system to a community bins system. To solve this problem, we apply both the weighting method, which has been used to solve similar problems in the literature, and a novel version of the augmented &#949;-constraint method (AUGMECON2). The results over simulated scenarios show that, in general, AUGMECON2 has a better performance, yielding a larger number of efficient solutions at lower computation times.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238078,"idioma_id":4,"titulo":"Characterization and Molecular Subtyping of Shiga Toxin Producing Escherichia coli Strains in Butcher Shops-MP-","resumen":"Shiga toxin?producing Escherichia coli (STEC) are important emerging foodborne human pathogens. Ruminants are the main animal reservoir of STEC currently known, and meat can become contaminated at different stages of the production chain. The aim of this work was to subtype and establish the epidemiological relatedness of non-O157 STEC strains isolated from ground beef and the environment in butcher shops before (evaluation stage, 2010?2011 period) and after (verification stage, 2013) implementing improvement actions.Sixty-eight non-O157 STEC strains were tested for eae, saa, ehxA, iha, efa1, toxB, subAB, cdt-V, astA, aggR, and aaiC genes, and stx1 and stx2 variants were determined. Pulsed-field gel electrophoresis (PFGE) was carried out with XbaI and XmaJI. From the 68 strains, 92.6%, 75.0%, 58.8%, 53.5%, 10.3%, 7.3%, and 4.4% werepositive for iha, ehxA, subAB, saa, cdt-V, astA, and eae, respectively. All strains were aggR\/aaiC-negative. PFGE showed that 19 strains grouped in 9 clusters and 41 showed unique XbaI patterns. During the evaluation stage (2010?2011), we identified clonal strains in different samples, circulating clones in different butcher shops, and more than one different strain in the same butcher shop. The bovine origin of meat and its manufacturing process could not ensure the total absence of all non-O157 STEC serotypes in this foodstuff. Most strains isolated during the evaluation (2010?2011) and verification (2013) stages did not exhibit a genotypic profile associated with human disease. It is necessary to conduct periodic reviews of the new epidemiological information and verify that the analyses of non-O157 STEC in food are appropriate to identify strains affecting the population.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238080,"idioma_id":5,"titulo":"Favoreciendo el desarrollo de conocimientos y competencias en el contexto de un Proyecto de Investigación-MP-","resumen":"En este trabajo se reflexiona a partir de la puesta en práctica, en el contexto de un Proyecto de Investigación y Desarrollo en la carrera de Ingeniería en Sistemas de Información, sobre la modalidad de ejecución del mismo tomando como base la filosofía ágil de desarrollo de software. Se pretende poner a prueba cómo esta modalidad no solo permite una planificación flexible del Proyecto sino que favorece el desarrollo del conocimiento y las competencias de sus integrantes desde etapas tempranas de su ejecución. Se pone en consideración la heterogeneidad de perfiles que integran el grupo de trabajo: docentes investigadores, maestrandos, graduados y alumnos con distintos estadíos de formación académica. En esta reflexión, que proviene de observar la dinámica en la adquisición de saberes y capacidades desarrollada en el grupo de trabajo durante el primer trimestre de vigencia del Proyecto, se procuran destacar las sinergias observadas que se producen entre los miembros del grupo donde todos aprenden de todos, con un fin común, y los resultados obtenidos en el desarrollo de conocimientos y competencias en pos de los objetivos del Proyecto, generando de esta manera nuevas formas de transferencia en los aprendizajes, la búsqueda de nuevos conocimientos o la mejora de los existentes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238082,"idioma_id":5,"titulo":"TIEMPO DE LATENCIA EN BROTES DE DENGUE DE ZONA TEMPLADA-MP-","resumen":"El Dengue es una enfermedad viral transmitida por el mosquito Aedes aegypti . En los últimos años la propagación de esta enfermedad en Argentina se ha transformado en un problema prioritario de salud pública, siendo la epidemia del 2015-2016 la mayor registrada. La posibilidad de predecir la evolución de esta enfermedad bajo distintas condiciones puede ser una herramienta de suma utilidad para la toma de decisiones en políticas de salud pública. En este trabajo se utilizó el modelado basado en agentes (MBA), implementado en RePast Simphony 2.4.0, desarrollado en la Facultad de Ingeniería de la Univ. Nac. de Entre Ríos. El modelo toma como entradas la población de Oro Verde, Entre Ríos, Argentina; la estimación de huevos del vector, a través de un relevamiento realizado en el año 2016 sobre ovitrampas y el perfil climatológico de la zona para el mismo año. Enel caso de aplicación que se presenta, se utiliza el modelo desarrollado para estimar los momentos críticos del año en los que el ingreso de individuos infectados puede iniciar una potencial epidemia sobre la población en estudio.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238086,"idioma_id":4,"titulo":"Surface charges and J H Poynting's disquisitions on energy transfer in electrical circuits-MP-","resumen":"In this paper we review applications given by J H Poynting (1884) on the transfer of electromagnetic energy in DC circuits. These examples were strongly criticized by O Heaviside (1887). Heaviside stated that Poynting had a misconception about the nature of the electric field in the vicinity of a wire through which a current flows. The historical review of this conflict and its resolution based on the consideration of electrical charges on the surface of the wires can be useful for student courses on electromagnetism or circuit theory.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238087,"idioma_id":4,"titulo":"Biophysical effect of climate change on summer crops-MP-","resumen":"The effect of climate change on yield of soybean and maize crops was determined in Azul, Buenos Aires, Argentina. DSSAT crop models, previously calibrated, were used, under local conditions. Projections of PRECIS regional climate model in the SRESA2stage were used, for the decades 2020-29 and 2050-59, in order to obtain potential yields. Later, the effect of heat waves during the growth cycle 2013-14 was evaluated. Climate projections indicated an increase of yields of crops during dryland farmingcrops. In soybean (Glycine max (L.) Merr.), the increase was 25 and 28 %, and in maize (Zea mays), it was 19 % and 26 %, for the decades 2020-29 and 2050-59, respectively. However, considering thermal variability imposed by the heat wave, it was evidentthat soybean and maize showed a reduction of yield when they are sown without irrigation during those extreme events. Yield decreases reach 19 % in soybean and 36 % in maize. Comparing yields of crops irrigated in a year considered as typical with respectof the year of heat wave, the increase of temperature benefits maize with a 22 % of yield increase, but harms soybean with a decrease of 13 %. Influence of temperature increase, together with water deficiencies, produces different effects on C3 species like soybean,and in C4 like maize. It is suggested to develop more research on the effects of extreme phenomena on different phenological phases of crops so the sustainability of agroecosystems from the center of Buenos Aires province could be mantained.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238088,"idioma_id":4,"titulo":"Total ionization cross sections in particle and antiparticle collisions with rare gases-MP-","resumen":"In this contribution we analyze the total ionization cross sectionsby impact of electrons, positrons, protons and antiprotons in Ne,Ar, Kr and Xe. We compare theoretical results using the continuumdistorted wave eikonal initial state approximation with a detailedcompilation of the available experimental data for the fourprojectiles in each target. The charge and mass effects, and theconvergence at intermediate energies are discussed, which areimportant issues for antiparticle normalization. We remark theinfluence of the post-collisional Auger-like electron emission,which is decisive to describe the total ionization of Kr and Xe atimpact velocities above 9 a.u.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238090,"idioma_id":4,"titulo":"Dengue Virus 1 Outbreak in Buenos Aires, Argentina, 2016","resumen":"The largest outbreak of dengue in Buenos Aires, Argentina, occurred during 2016. Phylogenetic, phylodynamic, and phylogeographic analyses of 82 samples from dengue patients revealed co-circulation of 2 genotype V dengue virus lineages, suggesting that this virus has become endemic to the Buenos Aires metropolitan area.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238093,"idioma_id":4,"titulo":"Semisynthetic esters of 17-hydroxycativic acid with in vitro cytotoxic activity against leukemia cell lines","resumen":"A collection of sixteen semisynthetic 17-hydroxycativic acid esters with alcohols containing a tertiary amine group was evaluated for their in vitro cytotoxicity against two human cancer cell lines, THP-1 and U937, and for their effects on the cell cycle and cell death. While 17-hydroxycativic acid itself is not cytotoxic, all the esters displayed cytotoxic activity, with GI50 values ranging between 3.2 µM and 23.1 µM. In general, the most potent compounds in both cell lines were esters with four carbon long alcohol residues. There was no clear relationship between the identity of the terminal secondary amine and the activity of the compound. Experiments using the 6-(pyrrolidin-1-yl)pentyl ester, 2c, revealed that this compound activates caspases-3\/7 and causes PARP-1 fragmentation in THP-1 and U937 cells, indicating the induction of apoptotic cell death. These results suggest that further investigation into the anticancer activity of diterpene derivatives and other labdane diterpenes may be fruitful.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238095,"idioma_id":4,"titulo":"CRISPR-Cpf1 mediates efficient homologous-directed repair and temperature-controlled genome editing-MP-","resumen":"Cpf1 is a novel class of CRISPR-Cas DNA endonucleases, with a wide range of activity across different eukaryotic systems. Yet, the underlying determinants of this variability are poorly understood. Here, we demonstrate that LbCpf1, but not AsCpf1, ribonucleoprotein complexes allow efficient mutagenesis in zebrafish and Xenopus. We show that temperature modulates Cpf1 activity by controlling its ability to access genomic DNA. This effect is stronger on AsCpf1, explaining its lower efficiency in ectothermic organisms. We capitalize on this property to show that temporal control of the temperature allows post-translational modulation of Cpf1-mediated genome editing. Finally, we determine that LbCpf1 significantly increases homology-directed repair in zebrafish, improving current approaches for targeted DNA integration in the genome. Together, we provide a molecular understanding of Cpf1 activity in vivo and establish Cpf1 as an efficient and inducible genome engineering tool across ectothermic species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238096,"idioma_id":4,"titulo":"EN REVISION: RES complex is associated with intron definition and required for zebrafish early embryogenesis-MP-","resumen":"Pre-mRNA splicing is a critical step of gene expression in eukaryotes. Transcriptome- wide splicing patterns are complex and primarily regulated by a diverse set of recognition elements and associated RNA-binding proteins. The retention and splicing (RES) complex is formed by three different proteins (Bud13p, Pml1p and Snu17p) and is involved in splicing in yeast. However, the importance of the RES complex for vertebrate splicing, the intronic features associated with its activity, and its role in development are unknown. In this study, we have generated loss-of-function mutants for the three components of the RES complex in zebrafish and showed that they are required during early development. The mutants showed a marked neural phenotype with increased cell death in the brain and a decrease in differentiated neurons. Transcriptomic analysis of bud13, snip1 (pml1) and rbmx2 (snu17) mutants revealed a global defect in intron splicing, with strong mis-splicing of a subset of introns. We found these RES-dependent introns were short, rich in GC and flanked by GC depleted exons, all of which are features associated with intron definition. Using these features, we developed and validated a predictive model that classifies RES dependent introns. Altogether, our study uncovers the essential role of the RES complex during vertebrate development and provides new insights into its function during splicing.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238097,"idioma_id":4,"titulo":"Antimicrobial resistant Escherichia coli in the reproductive tract microbiota of cows and sows","resumen":"Escherichia coli is a natural colonizer of the urogenitalmucosa of healthy females; however it is one of the pathogens associatedto reproductive failures in cows and sows. A better knowledge about thecharacteristics of native E. coli will allow us to differentiate themfrom pathogenic strains. Ninety autochthonous isolates from thereproductive tract of sows and cows were characterized to determine thephylogenetic profile, antibiotic resistance and virulence factors; also,comparisons between different breeding systems were performed. Vaginalcolonization of E. coli was statistically higher in cows (57.5%) thansows (23.8%), and most isolates belonged to the phylogenetic group A:79.69 and 80.77%, respectively; moreover phylo-groups B1 (12.5 and11.54%) and D (7.81 and 7.69%) were significantly lower; however, nonewas classified as B2. Positive associations between virulence factors andgroup D were found. Isolates with antimicrobial susceptibility wereassociated with group A and the MDR (Multiple Drug Resistance) wasrelated to the porcine source. These results contribute to the knowledgeof extra-intestinal E. coli populations; which could affect thereproductive performance of females.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238098,"idioma_id":5,"titulo":"Estimación del peso vivo a través de la medición del perímetro torácico en cabras criollas formoseñas (Argentina)","resumen":"Uno de los principales problemas de manejo que ocurren en el campo, es la estimación del peso vivo de los animales, que se hace de forma subjetiva y basándose netamente en la pericia del productor o técnico actuante, haciendo necesaria la búsqueda de una herramienta con base técnica que permita disminuir algunos errores de manejo, originados por la falta de precisión al momento de estimar el peso vivo. El objetivo de estudio fue obtener funciones de predicción del peso vivo (PV) a partir de las mediciones del perímetro torácico (PT) en cabras adultas criollas formoseñas. Y mediante el modelo matemático de regresión lineal simple, confeccionar una tabla de predicciones de peso vivo factible de ser utilizada por los productores. Se utilizaron 126 hembras caprinas criollas formoseñas de Laguna Yema (Argentina) con más de 4 dientes según cronometría dentaria. Se hallaron los estadísticos descriptivos, calculándose los principales estadísticos de tendencia central y dispersiva. Se comprobó la normalidad de los datos obtenidos mediante la prueba de Shapiro-Wilks modificada, posteriormente se efectuó el análisis del coeficiente de correlación de Pearson, el cual determinó una correlación (0,88) positiva, considerable y significativa (p<0,001). El PV puede ser estimado usando la ecuación de regresión lineal simple: PV= (-26,1) + 0,77*PT (R2 ajustado=0,78 y p<0,001), con error estimado de 3,41 kg. El uso del PT para predecir el PV podría ser una herramienta útil, porque la mayoría no posee instrumentos objetivos para determinarlo, resultando ésta una técnica factible de realizar sin la necesidad de utilizar una balanza, lo cual aumentaría la eficiencia en los pequeños y medianos productores que utilizan este recurso zoogenético local en el centro oeste formoseño.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238099,"idioma_id":4,"titulo":"Construction of low&#8209;ethanol wine yeasts through partial deletion of the Saccharomyces cerevisiae PDC2 gene-MP-","resumen":"We propose an alternative GMO based strategy to obtain Saccharomyces cerevisiae mutant strains with a slight reduction in their ability to produce ethanol, but with a moderate impact on the yeast metabolism. Through homologous recombination, two truncated Pdc2p proteins Pdc2p&#916;344 and Pdc2p&#916;519 were obtained and transformed into haploid and diploid lab yeast strains. In the pdc2&#916;344 mutants the DNA-binding and transactivation site of the protein remain intact, whereas in pdc2&#916;519 only the DNA-binding site is conserved. Compared to the control, the diploid BY4743pdc2&#916;519 mutant strain reduced up to 7.4% the total ethanol content in lab scale-vinifications. The residual sugar and volatile acidity was not significantly affected by this ethanol reduction. Remarkably, we got a much higher ethanol reduction of 10 and 15% when the pdc2&#916;519 mutation was tested in a native and a commercial wine yeast strain against their respective controls. Our results demonstrate that the insertion of the pdc2&#916;519 mutation in wine yeast strains can reduce the ethanol concentration up to 1.89% (v\/v) without affecting the fermentation performance. In contrast to non-GMO based strategies, our approach permits the insertion of the pdc2&#916;519 mutation in any locally selected wine strain, making possible to produce quality wines with regional characteristics and lower alcohol content. Thus, we consider our work a valuable contribution to the problem of high ethanol concentration in wine.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238105,"idioma_id":4,"titulo":"Non-destructive evaluation and contrasts of concrete overheated and abruptly cooled-MP-","resumen":"Concrete structures can suffer different pathologies, one of which may be due to exposure to high temperatures. In this briefing article, different concrete types were exposed to high temperatures. To simulate fire extinction, where the temperature of the overheated concrete descends suddenly, different cooling systems were applied: slowly cooling in the open air and fast cooling by spraying different water volumes. Physical and mechanical properties were affected by the increase of the temperature, making damages worst, when water is used as a cooling system. Sclerometer and Ultrasound non-destructive tests were conducted to quantify deterioration and a relationship with the compressive strength results was performed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238106,"idioma_id":5,"titulo":"Factores que inciden en el establecimiento y la permanencia de la violencia de género-MP-","resumen":"Esta investigación tiene como objetivo analizar los factores que inciden en el establecimiento y la permanencia de la violencia de género. Se investiga el fenómeno de la violencia, basándose en la teoría psicoanalítica, y se pretende explicar cómo el desarrollo de la personalidad se encuentra influenciada por modelos de aprendizajes primarios. Para abordar la realidad estudiada se llevó a cabo un taller de concientización de la violencia destinado a mujeres que se encontraban alojadas en un Hogar de refugio para víctimas de violencia. La modalidad de trabajo fue grupal, a partir de la intervención se exploraron indicadores de mecanismos de defensa. El caso que se tomó para su posterior análisis el de una de ellas, afectada a un vínculo conyugal violento por más de treinta años. En la víctima se pudo indagar las características más relevantes de su infancia y su correspondencia con las conductas actuales, los modos y patrones de reacción, su estado y mecanismos psicológicos y las características del vínculo conyugal, por esto se administraron técnicas proyectivas, entre ellas, entrevista inicial, dibujo de la persona humana (DFH) y persona bajo la lluvia. Los resultados del análisis posibilitaron visualizar características e indicadores comunes en mujeres víctimas, entre ellos, el uso de defensas: como la proyección y la anulación. Se observó cómo la construcción del vínculo conyugal disfuncional está teñido por modelos de aprendizajes primarios transferidos a través de la primera agencia socializadora, la familia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238107,"idioma_id":5,"titulo":"Clasificación mecánica de tablas de pinos resinosos cultivados en el nordeste de Argentina","resumen":"En este artículo se presentan y discuten los resultados de una investigación orientada al análisis demodelos mecánicos para clasificar por resistencia tablas de pino resinoso cultivado en el nordeste deArgentina. El programa experimental se llevó a cabo según los lineamientos de las normas europeasEN sobre una muestra de 233 tablas de tamaño estructural ensayadas a flexión y sobre otra conteniendo100 tablas ensayadas en tracción paralela a las fibras. Se diseñaron dos modelos, uno empleando elmódulo de elasticidad global como parámetro simple y otro basado en un parámetro combinado queincluyó al módulo de elasticidad junto a la densidad y la nudosidad. Los resultados mostraron unamayor eficiencia en los modelos desarrollados que en el método visual adoptado por la norma IRAM.Esa mayor eficiencia se puso de manifiesto en i) el alcance de los valores característicos adoptadospara las propiedades principales en la normativa vigente; ii) un aumento del rendimiento en los gradosestructurales y, iii) una disminución de la dispersión en los valores del módulo de elasticidad dentro decada clase resistente, lo cual permite estar en línea con la variabilidad adoptada por las reglas de diseñoestructural del país.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238113,"idioma_id":5,"titulo":"Validación del IAPS en niños y adolescentes argentinos","resumen":"El objetivo del estudio fue analizar el comportamiento psicométrico del conjunto de imágenes para niños y adolescentes del International Affective Picture System. La muestra estuvo compuesta por 141 niños y adolescentes de entre 7 y 14 años, divididos en tres franjas etarias que evaluaron las 60 imágenes en las dimensiones de valencia y arousal. Los resultados mostraron una baja activación para las imágenes consideradas agradables y alta activación para las imágenes consideradas desagradables, con una correlación fuerte y negativa para las segundas. La distribución de las imágenes en el espacio afectivo evidenció una mayor dispersión y menor inclinación de la activación para las imágenes agradables respecto de las desagradables. El comportamiento de la dimensión de valencia sostiene a ésta como el eje principal sobre la cual se organizan las emociones, la cual está vinculada con el proceso de adaptación y evolución humana, a diferencia de la dimensión de arousal que estaría más influenciada por factores socioculturales y de aprendizaje. La distribución de los estímulos afectivos en el espacio bidimensional refleja la organización de las emociones para niños y adolescentes argentinos, demostrándose que el IAPS puede ser un instrumento fiable para evaluar emociones en esta población.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238114,"idioma_id":4,"titulo":"Molecular Insights into Protein-Polyphenols Aggregation. A Dynamic and Topological Description","resumen":"Protein&#8208;polyphenols interactions are of greatest interest in several fields like food technology and leather industry. Also, it is thought that these interactions are responsible for the undesired phenomenon of colloidal turbidity. However, there is sparse information about the molecular implications leading to this phenomenon. In this study, Molecular Dynamic (MD) simulations in conjunction with the analysis of the topology of the electron density are used to study protein\/polyphenol interactions in a model system which consists of a ternary mixture of water, the flavonoids Catechin and Procianidin B3 and proline pentapeptides. After 50 ns of simulation, root mean square deviation, root mean square fluctuation and number of hydrogen bonds were calculated. Information about the intermolecular interactions that drive the assembly of colloidal complexes has been obtained by the analysis of the electron charge density. Results show the formation of a stable adduct, with a very complex network of conventional and non&#8208;conventional hydrogen bonds. This study has also shown the significance of C&#8208;H&#8901;&#8901;&#8901;O and C&#8208;H&#8901;&#8901;&#8901;&#960; interactions in the phenomenon of colloidal turbidity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238117,"idioma_id":4,"titulo":"Bubble nucleation and growth in very strong cosmological phase transitions","resumen":"Strongly first-order phase transitions, i.e., those with a large order parameter, are characterized by a considerable supercooling and high velocities of phase transition fronts. A very strong phase transition may have important cosmological consequences due to the departures from equilibrium caused in the plasma. In general, there is a limit to the strength, since the metastability of the old phase may prevent the transition to complete. Near this limit, the bubble nucleation rate achieves a maximum and thus departs from the widely assumed behavior in which it grows exponentially with time. We study the dynamics of this kind of phase transitions. We show that in some cases a gaussian approximation for the nucleation rate is more suitable, and in such a case we solve analytically the evolution of the phase transition. We compare the gaussian and exponential approximations with realistic cases and we determine their ranges of validity. We also discuss the implications for cosmic remnants such as gravitational waves.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238122,"idioma_id":4,"titulo":"Selection on MHC in a Context of Historical Demographic Change in 2 Closely Distributed Species of Tuco-tucos (Ctenomys australis and C. talarum)","resumen":"Selection necessarily acts within the same current and historical demographic framework as neutral evolutionary processes, and the outcome of the interplay between these forces may vary according to their relative strength. In this study, we compare the variation at an MHC locus (DRB exon 2), typically subject to strong diversifying selection, and mitochondrial diversity (D-loop) across populations encompassing the entire distribution of two species of South American subterranean rodents: Ctenomys australis and C. talarum (tuco-tucos). Although these species are parapatric along most of their distribution, historically they have followed distinct demographic trajectories associated with sea level changes during the Quaternary. We surveyed 8 populations of C. australis and 15 of C. talarum, from which we analyzed 70 and 212 D-loop haplotypes and 91 and 346 DRB genotypes, respectively. Both species have gone through a recent demographic expansion; however, the signal of this process only encompasses the entire distribution of one of the species: C. australis. While balancing selection on MHC in C. talarum enhanced DRB diversity at the local level compared to D-loop, although not promoting divergence among populations, in C. australis local diversifying selection may have driven higher population differentiation at DRB than at D-loop.  Our findings reinforce the idea that the relative strength of selection acting on MHC genes varies spatially and temporally within and among species, even between species using the same macrohabitat and exposed to similar immune challenges.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238123,"idioma_id":4,"titulo":"Hydrogenolysis of glycerol to 1,2-propanediol in a continuous flow trickle bed reactor","resumen":" The reaction of hydrogenolysis of glycerol was studied in a trickle-bed three phase reactor. A thermodynamic study of possible reactions was performed. A feasible reaction network at the reaction conditions was thus written, made up of 9 reactions, including glycerol hydrogenolysis, hydrogenations and dehydrations. The phase equilibrium properties of the feedstock at the reactor inlet conditions were verified, in order to assess the relative concentration of the three phases. At all reaction conditions it was found that three phases, solid, liquid and gas, coexisted in the reactor, and that the flow pattern of the system was 'trickling'. Two catalysts were tested in the reaction test of hydrogenolysis of glycerol to 1,2-propanediol, copper chromite and Cu\/Al2O3. The catalysts were further characterized by ICP, nitrogen sortometry, XPS, XRD, TPR and pyridine-TPD. The catalysts were quite different in composition, acidity and other physicochemical properties. In spite of these differences a similar behavior in reaction was seen. The average reaction rate per unit catalyst mass was found to be practically constant at different varying conditions. The results pointed out to the possible presence of mass transfer limitations and therefore all resistances of the system were estimated with the aid of measured and estimated properties. This study indicated that the resistance to mass transfer of hydrogen from the gas phase to the liquid phase dominated the overall kinetics of the reactor. The overall pellet resistance by diffusion and reaction was estimated to be the smallest (RDR ¡Ö 5 s). The liquid-solid resistance (RSL ¡Ö 23-40 s) had an intermediate value. Hydrogen G-L mass transfer resistance was found to be the highest (RG-L ¡Ö 50-280 s) and thus controlled the overall reaction rate. Operation conditions were varied in different ranges (temperature 210-250 ¡ãC; pressure 8-20 bar and LHSV 1.9-5.63 h-1). It was found that when the temperature was increased the selectivity to 1,2-propanediol was also increased and that a maximum existed at 230 ¡ãC (97 %). At higher temperatures selectivity was decreased and different compounds were also produced, with varying nature and amount depending on the catalyst acidity. When the pressure was increased the selectivity to 1,2-propanediol was also increased, up to a value of 97% at 14 bar. Higher pressures did not modify this selectivity value. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238125,"idioma_id":5,"titulo":"'Coplera del viento'. La presencia de Oscar Matus y del Nuevo Cancionero en el Encuentro de la Canción Protesta de 1967","resumen":"García, María Inés y María Emilia Greco: «?Coplera del viento?. La presencia de OscarMatus y del Nuevo Cancionero en el Encuentro de la Canción Protesta de 1967», enBoletín Música, Casa de las Américas, No. 45, Nueva época, enero-abril, 2017, pp. 25-39.RESUMENManuel Oscar Matus fue uno de los músicos argentinos que participó del Encuentrode la Canción Protesta realizado en Cuba en agosto de 1967. El artículo propone unrecorrido por las prácticas musicales de Matus y su posicionamiento estético e ideológico como miembro fundador del Movimiento del Nuevo Cancionero de la Argentina.Se analizan sus composiciones y su actividad como productor discográfico independiente, con el objetivo de indagar en sus motivaciones y afirmar la pertinencia de suparticipación en dicho encuentro.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238133,"idioma_id":4,"titulo":"Monolithic reactor for VOCs abatement: Influence of non-uniformity in the coating","resumen":"This article presents a theoretical study of the catalytic mineralisation of ethanol via acetaldehyde over manganese - copper mixed oxide catalyst deposited on a monolith reactor. The steady-state operation of the monolith reactor is represented by means a heterogeneous, one-dimensional, adiabatic model, which accounts for external (gas-solid) resistances to mass and heat transfer and internal resistances to mass transfer inside the catalytic coating (washcoat). The effect of catalyst accumulation at the corners of a square section channel is analysed. Under the operating conditions considered, the diffusional resistances have a significant effect on the effective rate of removal of Volatile Organic Compounds and cannot be neglected. Non-uniform coating causes a considerable deterioration of the averaged effectiveness factors of the two reactions under consideration and lower temperatures along the reactor are found. These lower temperatures, together with lower temperature drops over the external film cause additional negative impacts on the Volatile Organic Compounds conversion. The decrease in the reactor performance, caused by the catalyst accumulation, is magnified as the feed concentration rises. Consequently, higher feed temperatures and\/or lower space velocities are necessary to ensure the complete destruction of the volatile organic compounds involved (ethanol and acetaldehyde).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238136,"idioma_id":5,"titulo":"Argentina 1982, primer ensayo para la construcción de un cuerpo cyborg. A propósito de 'Primera línea' de Carlos Gardini","resumen":"El presente trabajo propone una reflexión en torno a la emergencia de la estética cyberpunk en Argentina durante la década del ochenta a partir del análisis del cuento 'Primera línea' de Carlos Gardini. La relevancia de la propuesta es doble. En primer término, el texto es el primer exponente de la estética cyberpunk en Argentina y antecede incluso la publicación de Neuromancer (1984) de William Gibson, el cual es considerado el primer emergente de este subgénero de la ciencia ficción a nivel mundial. En segundo lugar (y de mayor relevancia aún), en tanto el texto de Gardini irrumpe (de forma contemporánea a Los Pichiciegos de Rodolfo Fogwill) en el escenario cultural argentino como el primer relato de representación de la Guerra de Malvinas. Precisada la presentación del texto, este trabajo propone un acercamiento a la pregunta sobre la emergencia del cuerpo cyborg (simbiosis entre humano y máquina) en el contexto de un escenario socio-histórico y cultural nacional que, en las postrimerías de la última dictadura cívico-militar argentina, se encuentra impregnado por los interrogantes sobre el cuerpo: el cuerpo ausente, el cuerpo torturado, el cuerpo mutilado en la guerra.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238137,"idioma_id":4,"titulo":"Using niche-modelling and species-specific cost analyses to determine a multispecies corridor in a fragmented landscape","resumen":"Misiones, Argentina, contains the largest remaining tract of Upper Paraná Atlantic Forest ecoregion; however, ~50% of native forest is unprotected and located in a mosaic of plantations, agriculture, and pastures. Existing protected areas are becoming increasingly isolated due to ongoing habitat modification. These factors, combined with lower than expected regional carnivore densities, emphasize the need to understand the effect of fragmentation on animal movement and connectivity between protected areas. Using detection dogs and genetic analyses of scat, we collected data on jaguars (Panthera onca), pumas (Puma concolor), ocelots (Leopardus pardalis), oncillas (Leopardus tigrinus), and bush dogs (Speothos venaticus) across habitats that varied in vegetation, disturbance, human proximity, and protective status. With MaxEnt we evaluated habitat use, habitat suitability, and potential species richness for the five carnivores across northern-central Misiones, Argentina. Through a multifaceted cost analysis that included unique requirements of each carnivore and varying degrees of overlap among them, we determined the optimal location for primary\/secondary corridors that would link the northern-central zones of the Green Corridor in Misiones and identified areas within these corridors needing priority management. A secondary analysis, comparing these multispecies corridors with the jaguar?s unique requirements, demonstrated that this multispecies approach balanced the preferences of all five species and effectively captured areas required by this highly restricted and endangered carnivore. We emphasize the potential importance of expanding beyond a single umbrella or focal species when developing biological corridors that aim to capture the varied ecological requirements of coexisting species and ecological processes across the landscape. Detection dogs and genetic analyses of scat allow data on multiple species to be collected efficiently across multiple habitat types independent of the degree of legal protection. These data used with multifocal GIS analyses balance the varying degree of overlap and unique properties among them allowing for comprehensive conservation strategies to be developed relatively rapidly. Our comprehensive approach serves as a model to other regions faced with habitat loss and lack of data. The five carnivores focused on in our study have wide ranges, so the results from this study can be expanded and combined with surrounding countries, with analyses at the species or community level.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238138,"idioma_id":4,"titulo":"OXIDATION OF ETHYL ACETATE ON Fe-Mn OXIDES FROM NITRATES \tDEPOSITED BY IMPREGNATION ON MONOLITHS OF AISI 304 STAINLESS STEEL","resumen":"The iron-manganese mixed monolithic catalysts were obtained by impregnation from nitrates as precursors. A monolithic support was studied with and without alumina as surface generator. The characterization consisted in XRD, SEM, Adherence test, SBET and TPR. The monolith was evaluated in the combustion of ethyl acetate. The preparation method was very satisfactory in terms of reproducibility and adherence of the deposited phase. The higher activity of IFeMnx with respect to Al3FeMnx may be attributed for the formation of the solid solution where the Fe is introduced to the bixbyite structure. However, the presence of defective MnOx species in monoliths without alumina which might help to improve their performance is observed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238142,"idioma_id":4,"titulo":"Co-invasive exotic pines and their ectomycorrhizal symbionts show capabilities for wide distance and altitudinal range expansion","resumen":"We asked if exotic Pinus elliotti seedlings can survive and form ectomycorrhizas at higher elevations andlong distances from their current range, and which ECM partners disperse to these soils. We selectedthree plots at four grassland sites along an altitudinal gradient (900, 1600, 2200, and 2700 m asl)established at c. 110, 3000, 6000, and 9000 m from the closest pine plantation, respectively. We combinedfield experiments with glasshouse assays to assess survival and ECM fungi in roots and soils. A pineplantation close to the lowest site was also selected for DNA metabarcoding of soils. Pine seedlingssurvived at all altitudes but not all formed mycorrhizas. They formed mycorrhizas with Suillus granulatusat 900, 1600, and 2200 m asl (i.e. up to 6000 m from the closest pine plantation), and with Rhizopogonpseudoroseolus and Thelephora terrestris at lower altitudes and distances. Twelve ECM fungal OTUs werefound in grasslands and 34 were detected in the pine plantation. Although richness and abundance ofECM fungi decreased with increasing distance from the pine plantation, there was at least one non-nativeECM fungal species present in each sampling site, even at 2700 masl and 9000 m distance from theclosest plantation. This study provides evidence that the availability of suitable fungal symbionts mightconstrain but not hinder the expansion of a pine species over wide distances and altitudinal zones evenin areas with no native ECM fungi","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238143,"idioma_id":4,"titulo":"Effects of cropping systems under no-till agriculture on arbuscular mycorrhizal fungi in Argentinean Pampas","resumen":"Here, we compare arbuscular mycorrhizal fungi (AMF) communities and fatty acids in soils under different no-till (NT) agricultural managements over two seasons in two consecutive years. Two NT practices with different agricultural managements were compared: crop rotation (CR) and soya bean monoculture (MC). Soils of natural grasslands (NGs) were used as a reference. Treatments were tested along a regional gradient (four geographical locations) across a 400-km transect of the Argentinean Pampas. We identified 46 morphospecies. Several morphospecies occurred abundantly at all soils; others appeared to be restricted to specific situations. At the regional scale, CR maintained the same richness levels of AMF spores, whereas MC showed less richness, when compared with the NG. Although AMF spore density was clearly affected by cropping practices in the four locations, we could observe some changes in AMF species richness, and similar diversity under agricultural and natural soils. Fatty acid concentrations (whole-cell, phospholipid and neutral lipid fatty acids) revealed differences between soil managements and showed similar patterns of variation in all locations. Spore density positively correlated with all soil lipids fractions. The results suggest that AMF spore communities and fatty acids in soils are suitable indicators of soil management involving different levels of crop rotation. Spore richness measured at a regional scale proved to be sensitive to different NT agricultural managements. Moreover, certain morphospecies could be good bioindicators for NT practices based on cropping systems on the Argentinean Pampas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238144,"idioma_id":4,"titulo":"RATIO BETWEEN AMOUNT AND NATURE OF Mn-Cu MIXED OXIDE AND THE COMBUSTION MECHANISM OF ETHANOL AND N-HEXANE IN HONEYCOMD TYPE CATALYSTS","resumen":"Mn-Cu mixed oxides were deposited by ultrasonic impregnation on ceramic honeycomb monoliths. Itscatalytic performance was evaluated in the combustion of ethanol and n-hexane, VOC molecules of differentchemical nature. The catalysts were characterized by N2 physisorption, SEM-EDS, XRD, X-ray fluorescence,XPS, TPR, TPD-O2 and OSC measurements. It was observed that the catalyst with the lowestcontent of Mn-Cu phase was the most active in the combustion of ethanol. This was attributed to thehigher content of Mn4+ and the increase of lattice oxygen mobility, which would favor a Mars-vanKrevelen type mechanism. The catalyst with a medium content of Mn-Cu, proved to be the most activein the combustion of n-hexane. This was associated with a high content of oxygen vacancies and easyavailability of oxygen adsorbed on the surface, promoting the combustion of n-hexane, possibly througha Rideal-Eley type mechanism. The catalyst with the highest content of the Mn-Cu phase showed lowactivity in combustion of ethanol and n-hexane, which was attributed to a higher crystallinity of theMn-Cu phases generated.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238148,"idioma_id":4,"titulo":"On the internal structure of piezo-electric devices: Closed and Open Loop Optimal Strategies","resumen":"Piezo-electric devices possess the ability to produce high voltages without load. However, to harvest this energy, the complex and capacitive internal structure must be deal with. This capacitive behavior makes the AC-DC conversion too involved. If a buck-boost topology is to be designed to regulate the DC output, the discontinuous mode provides constant input impedance for small amount of power. However, the input impedance of a buck-boost is a function of the switching frequency and inductance, bounding the maximum values. This open-loop strategy is adequate for small size PCB applications, for instance in energy harvesting applied to sensors, whereas, closed-loop and optimal control algorithms will improve the output power. In this paper a closed-loop optimal control algorithm to work with any source of electrical input voltage in a buck-boost converter is considered. This optimal control yields a much bigger output power when compared to the case of non-optimal control. With piezo-electric devices, the output power harvested shows a significant improvement, thus mitigating their natural drop in open loop. Some simulations as well as comparisons with real measurements using two different kind of commercial piezo-electric devices are presented. On the other hand, the internal structure of piezo-electric generators is explored using an open loop optimal control strategy along with an intermediate active circuit. Following the reading of the measurements and the theory developed in this paper, conclusions and future work are provided.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238149,"idioma_id":4,"titulo":"Chemotaxis detection towards chlorophenols using video processing analysis","resumen":"To our knowledge, this communication is the first report of chemotaxis towards chlorophenols by any bacteria.We used a recently published method based on the agarose in-plug assay combined with video processing analysisand we also present a new index of bacterial mean speed for these assays.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238151,"idioma_id":4,"titulo":"In vitro and in vivo characterization of anodised zirconium as a potential material for biomedical applications","resumen":"In vitro studies offer the insights for the understanding of the mechanisms at the tissue?implant interface that will provide an effective functioning in vivo. The good biocompatibility of zirconium makes a good candidate for biomedical applications and the attractive in vivo performance is mainly due to the presence of a protective oxide layer. The aim of this study is to evaluate by in vitro and in vivo approach, the influence of surface modification achieved by anodisation at 30 and 60V on zirconium implants on the first steps of the osseointegration process. In this study cell attachment, proliferation and morphology of mouse myoblast C2C12-GFP and in mouse osteoprogenitor MC3T3-E1 cells was evaluated. Also, together with the immune system response, osteoclast differentiation and morphology with RAW 264.7 murine cell line were analized.  It was found that anodisation treatment at 60V enhanced cell spreading and the osteoblastic and osteoclastic cells morphology, showing a strong dependence on the surface characteristics.  In vivo tests were performed in a rat femur osteotomy model. Dynamical and static histological and histomorphometric analyses were developed 15 and 30 days after surgery. Newly formed bone around Zr 60V implants showed a continuous newly compact and homogeneous bone just 15 after surgery, as judged by the enhanced thickness and mineralization rate. The results indicate that anodising treatment at 60V could be an effective improvement in the osseointegration of zirconium by stimulating adhesion, proliferation, morphology, new bone thickness and bone mineral apposition, making zirconium an emerging candidate material for biomedical applications.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238157,"idioma_id":4,"titulo":"Sound Spectrum Influences Auditory Distance Perception of Sound Sources Located in a Room Environment","resumen":"Previous studies on the effect of spectral content on auditory distance perception (ADP) focused on the physically measurable cues occurring either in the near field (low-pass filtering due to head diffraction) or when the sound travels distances >15 m (high-frequency energy losses due to air absorption). Here, we study how the spectrum of a sound arriving from a source located in a reverberant room at intermediate distances (1?6 m) influences the perception of the distance to the source. First, we conducted an ADP experiment using pure tones (the simplest possible spectrum) of frequencies 0.5, 1, 2, and 4 kHz. Then, we performed a second ADP experiment with stimuli consisting of continuous broadband and bandpass-filtered (with center frequencies of 0.5, 1.5, and 4 kHz and bandwidths of 1\/12, 1\/3, and 1.5 octave) pink-noise clips. Our results showed an effect of the stimulus frequency on the perceived distance both for pure tones and filtered noise bands: ADP was less accurate for stimuli containing energy only in the low-frequency range. Analysis of the frequency response of the room showed that the low accuracy observed for low-frequency stimuli can be explained by the presence of sparse modal resonances in the low-frequency region of the spectrum, which induced a non-monotonic relationship between binaural intensity and source distance. The results obtained in the second experiment suggest that ADP can also be affected by stimulus bandwidth but in a less straightforward way (i.e., depending on the center frequency, increasing stimulus bandwidth could have different effects). Finally, the analysis of the acoustical cues suggests that listeners judged source distance using mainly changes in the overall intensity of the auditory stimulus with distance rather than the direct-to-reverberant energy ratio, even for low-frequency noise bands (which typically induce high amount of reverberation). The results obtained in this study show that, depending on the spectrum of the auditory stimulus, reverberation can degrade ADP rather than improve it.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238159,"idioma_id":5,"titulo":"Prácticas de participación política. Experiencias de socialización de jóvenes en la ?nocturna?","resumen":"En este artículo se analiza uno delos ejes de las entrevistas realizadas a jóvenes provenientes de dos escuelassecundarias nocturnas en Viedma, Río Negro, Argentina, a partir deinterrogantes destinados a conocer lasprácticas de participación política de los y las jóvenes, en tanto experiencias de socialización en la escuelamedia nocturna. En las prácticas de participación política sevisibilizan diferentes estrategias por parte de los estudiantes: la noparticipación, el desempeño como delegados de curso, en el Centro deEstudiantes, entre otras.Entre los resultados se advierte que, para algunosjóvenes, participar en el Centro de Estudiantes está más relacionado con lanecesidad de conformar un espacio con cierta autonomía respecto de los adultos,que con una estrategia política. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238160,"idioma_id":4,"titulo":"New parasitological findings for pre-Hispanic camelids","resumen":"Paleoparasitological examination provides information of parasite?host associations in the past, shedding light on the geographical origin of some parasites, on the possible dispersal routes and on some of the processes that modelled the parasitic communities. The aim of the present study was to examine parasite remains present in camelid coprolites collected from the archaeological site Alero Destacamento Guardaparque, Patagonia and to discuss the paleoparasitological findings in a biogeographical and paleoecological context. Coprolites were collected from different stratified layers dating from middleto late Holocene, a period covering approximately 7000 years. Paleoparasitological examination revealed the presence of eggs attributed to Lamanema chavezi or Nematodirus lamae, Nematodirus spathiger, Dictyocaulus sp., eggs of three unidentified capillariids, Strongylus-type eggs and oocysts of Eimeria macusaniensis. Enteric parasites of camelids had not changedsignificantly during the Holocene up to the entry of introduced livestock, although environmental conditions fluctuated greatly throughout this period, indicating the stability of these associations over time. This is the first finding of N. spathiger and Dictyocaulus sp. in paleoparasitological record and their presence are associated with the interaction of camelids with introduced livestock, which likely allowed parasite host switching. In the present study, the zoonotic importance of parasites of camelids is also discussed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238163,"idioma_id":5,"titulo":"Calidad microbiológica de hamburguesas degarbanzo elaboradas en forma artesanal y almacenadas bajo diferentes técnicas de refrigeración","resumen":"Seanalizó la calidad microbiológica de hamburguesas de garbanzoelaboradas en forma artesanal y almacenadas bajo diferentestemperaturas de refrigeración. Las hamburguesas refrigeradas (4°C)se analizaron cada 72-96 horas durante 21 días y las congeladas(-20°C) cada 15 días durante 98 días. Se investigaron BacteriasAerobias Mesófilas Totales (BAMT), Staphylococcusspp.identificando S.aureus,Bacilluscereus,coliformes totales, levaduras y hongos filamentosos conidentificación de géneros. En las hamburguesas refrigeradas ycongeladas predominaron las BAMT y se detectaron coliformes totales,aunque en ningún caso constituyeron microorganismos capaces deocasionar un riesgo potencial para la salud. No se observódesarrollo de B.cereusy S.aureus.Estos resultados evidencian que ambas formas de almacenamientopermiten obtener un producto microbiológicamente inocuo para serconsumido en los períodos de tiempo analizados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238164,"idioma_id":4,"titulo":"Chemical characterization, texture and consumer acceptability of yogurts supplemented with quinoa flour","resumen":"Quinoa can be used as a functional ingredient in food formulations. The aim of this study was to evaluate the effects on proximate composition, stability during storage, texture and consumer acceptability of yogurts supplemented with quinoa flour at 1, 3 and 5 g 100 mL-1. A product without supplementation was used as control. Products were assessed for moisture, carbohydrates, proteins, fats, total dietary fibre (TDF), ashes and minerals. The pH, acidity and syneresis of yogurts were measured after 1, 7, 14 and 14 21 days of storage and a Texture Profile Analysis (TPA) was carried out. Applying 15 hedonic scale, 102 consumers analyzed the overall acceptability, color, texture, flavor and aroma of yogurts. Supplemented products showed significant higher protein, carbohydrate and fat contents. Hardness and adhesiveness showed a negative association whereas a positive one was found between springiness and cohesiveness. Yogurt is not necessarily the adequate matrix for hauling quinoa compounds since the addition of greater amounts of 1 g 100 mL-1 quinoa flour had undesirable effects on gel stability (syneresis and increases in total acidity) and consumer acceptability.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238165,"idioma_id":5,"titulo":"Transición y Construcción de la Paternidad.","resumen":"Algunos hechos históricos trajeron aparejadas consecuencias sociales y psicológicas que llevaron a replantear las funciones de los padres. Lo que llevó a que las investigaciones centraran su interés en estudiar qué le ocurría al padre ante su paternidad. Por lo tanto el trabajo que se informa tuvo como objetivo realizar una revisión bibliográfica relacionada a la transición de la paternidad. En el mismo se pueden evidenciar diversas investigaciones que dan cuenta de distintos procesos emocionales que atraviesa el padre y cómo estos influyen en la relación con su familia de origen, pareja e hijo.Se observó que factores tales como la relación matrimonial, las demandas de trabajo, las relaciones tempranas con su familia de origen influyen en la construcción de la identidad paterna. Los estudios revisados destacan la importancia de entender qué le ocurre al padre durante ese período, ya que cómo lo viva incidirá en la relación con su hijo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238167,"idioma_id":5,"titulo":"Relación entre la sensibilidad paterna y los estilos de apego, la personalidad y la capacidad empática, según variables sociodemográficas","resumen":"El objetivo de este estudio fue comprobar si existe relación entre la sensibilidad paterna y los estilos de apego, los rasgos de personalidad y la capacidad empática, según variables sociodemográficas. Participaron 118 sujetos adultos hombres de la Provincia de Buenos Aires, Argentina cuyo rango de edad osciló entre 18 y 50 años (M= 33.80; DE = 5.644). Los instrumentos que se utilizaron fueron: Cuestionario de Sensibilidad Paterna, Big Five Inventory, Índice de Reactividad Interpersonal y el Cuestionario sobre relaciones. Los resultados demuestran que existe relación entre la sensibilidad del padre, los estilos de apego (seguro, evitativo, preocupado y temeroso); los rasgos de personalidad (extraversión, neuroticismo y agradabilidad); y la capacidad empática (toma de perspectiva, malestar personal y preocupación empática). De igual manera, se encontró correlación entre las escalas mencionadas anteriormente y las variables sociodemográficas tales como: edad del padre, edad del hijo, situación civil, situación laboral, cantidad de hijos y nivel de estudios paternos. Finalmente, los padres están que dispuestos a participar en todo lo relacionado al cuidado de su familia, no tienen miedo a establecer relaciones íntimas con los otros.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238168,"idioma_id":5,"titulo":"Diferencias entre la sensibilidad paterna según variables sociodemográficas","resumen":"Durante décadas, diversas investigaciones sostuvieron que la función del padre era la de proveedoreconómico. No obstante, con los cambios históricos que fueron sucediendo en las últimas décadas,muchos psicólogos se interesaron en conocer cuáles eran las funciones del padre y qué le ocurría durantela gestación de su hijo. Igualmente, se ha comprobado que las características socioculturales ysociodemográficas del padre influyen en el ejercicio y la transición hacia la paternidad. Por ello, estainvestigación se centró en analizar si existen diferencias entre los sentimientos, las emociones y lasreacciones de los padres durante la gestación y el nacimiento de su hijo con las variables sociodemográficas:edad paterna, niveles de estudio, estado civil, situación laboral, cantidad de hijos, edad de suhijo y sexo de su hijo. La muestra de este estudio estuvo compuesta por 170 padres con hijos menoresde dos años de edad. El diseño de estudio fue no experimental, de tipo descriptivo. Los instrumentosque se utilizaron fueron: cuestionario de sensibilidad paterna y una encuesta sociodemográfica dise-ñada para dicha investigación. Los resultados demuestran que existen diferencias entre la sensibilidaddel padre con respecto a la edad del padre, la edad del hijo y el nivel de estudios paternos, y no seencontraron diferencias entre esta y el estado civil, situación laboral, cantidad de hijos y sexo de loshijos. A modo de conclusión, la construcción y el desarrollo de la paternidad dependen de diversasvariables tales como el contexto social y cultural, su situación actual, entre otros y la conjunción detodas determinan la manera en que el padre se vincule con su hijo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238169,"idioma_id":5,"titulo":"LA QUINOA (Chenopodium quinoa Willd) Y SU ROL EN LA PREVENCIÓN DE ECNT","resumen":"Laquinoa es un pseudocereal que ha sido cultivado desde hace 7000 años porculturas pre-colombinas. Era un alimento básico en la dieta de los pueblos dela región Andina y los Incas lo llamaban ?el grano madre?. En los últimos años,el interés por el grano ha ido en ascenso debido al reconocimiento de sucalidad nutricional y la presencia de fitoquímicos. Asimismo, la demanda porproductos alimenticios a base de quinoa se ha incrementado gradualmente. Aunquelas propiedades funcionales de distintas semillas han sido revisadas, pocosartículos se han focalizado en aquellas correspondientes a la quinoa. Por lotanto, la intensión de esta revisión es exponer la composición nutricional, loscompuestos bioactivos de las semillas de quinoa y las implicancias para lasalud de su consumo. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238170,"idioma_id":5,"titulo":"Calidad Microbiológica de Dulce de Zanahorias elaborado con Sucralosa en forma Artesanal","resumen":"dulce de zanahorias","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238171,"idioma_id":5,"titulo":"El rol de la felicidad ajena en la filosofía práctica de Kant","resumen":"En este trabajo, presento e intento resolver un problema que la oposición de Kant al eudaimonismo podría plantear al segundo deber de virtud. Tras analizarlo, propondré que el deber de la felicidad ajena consigue disolver al menos uno de los obstáculos para alcanzar la felicidad en la Tierra (la felicidad propia empírica anhelada naturalmente por los seres humanos en tanto que seres racionales y finitos). El motivo de esto es que el deber de promover los fines de los demás logra reubicar la felicidad hedónica en el plano de la moralidad, algo que la noción intelectual de felicidad como componente del bien supremo no consigue hacer y en esto consiste el rol que el deber de la felicidad ajena cumple en el sistema ético kantiano.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238172,"idioma_id":4,"titulo":"The reduced myofilament responsiveness to calcium contributes to the negative force-frequency relationship in rat cardiomyocytes: role of reactive oxygen species and p-38 map kinase","resumen":"The force-frequency relationship (FFR) is an important intrinsic regulatory mechanism of cardiac contractility. However, a decrease (negative FFR) or no effect (flat FFR) on contractile force in response to an elevation of heart rate is present in the normal rat or in human heart failure. Reactive oxygen species (ROS) can act as intracellular signaling molecules activating diverse kinases as calcium-calmodulin-dependent protein kinase II (CaMKII) and p-38 MAP kinase (p-38K). Our aim was to elucidate the intracellular molecules implicated in the FFR of isolated rat ventricular myocytes. The myocytes were field-stimulated via two-platinum electrodes. Sarcomere length was recorded with a video camera. Ca2+ transients and intracellular pHi were recorded by epifluorescence. Increasing frequency from 0.5 to 3 Hz decreased cell shortening without changes in pHi. This negative FFR was changed to positive FFR when the myocytes were pre-incubated with the ROS scavenger MPG, the NADPH oxidase blocker apocynin, or by inhibiting mitochondrial ROS production with 5-HD. Similar results were obtained when the cells were pre-incubated with the CaMKII blocker, KN-93, or the p-38K inhibitor, SB-202190. Consistently, the levels of phosphorylation of p-38K and the oxidation of CaMKII were significantly higher at 2 Hz than at 0.5 Hz. Despite the presence of positive inotropic effect during stimulation frequency enhancement, Ca2+ transient amplitudes were reduced in MPG- and SB-202190-treated myocytes. In conclusion, our results indicate that the activation of the intracellular pathway involving ROS-CaMKII-p-38K contributes to the negative FFR of rat cardiomyocytes, likely by desensitizing the response of contractile myofilaments to Ca2+.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238173,"idioma_id":4,"titulo":"Post-Quantum Cryptography: S381 Cyclic Subgroup of High Order","resumen":"Abstract: Currently there is an active Post-Quantum Cryptography (PQC) solutionssearch, which attempts to find cryptographic protocols resistant to attacks bymeans of for instance Shor?s polynomial time algorithm for numerical fieldproblems like integer factorization (IFP) or the discrete logarithm (DLP). Theuse of non-commutative or non-associative structures are, among others, validchoices for these kinds of protocols. In our case, we focus on a permutationsubgroup of high order and belonging to the symmetric group S381.Using adequate one-way functions (OWF), we derived a Diffie-Hellman keyexchange and an ElGamal ciphering procedure that only relies on combinatorialoperations. Both OWF pose hard search problems which are assumed as notbelonging to BQP time-complexity class. Obvious advantages of present protocolsare their conceptual simplicity, fast throughput implementations, highcryptanalytic security and no need for arithmetic operations and thereforeextended precision libraries. Such features make them suitable for lowperformance and low power consumption platforms like smart cards, USB-keys andcellphones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238175,"idioma_id":5,"titulo":"EVALUACIÓN DE CARACTERES ASOCIADOS AL CRECIMIENTO INVERNAL EN CULTIVARES DE LOLIUM PERENNE Y BROMUS STAMINEUS","resumen":"El crecimiento de gramíneas en regiones templado húmedas es restringido durante el período de bajas temperaturas. Bromus stamineus mostró mayor productividad invernal que Lolium perenne a temperaturas relativamente bajas (i.e. 8 - 10 °C). Conocer las causas de estas diferencias inter-específicas tiene especial aplicabilidad y enorme relevancia. Por ejemplo, este conocimiento puede ser utilizado en programas de mejoramiento genético y de selección de materiales interesados en mejorar el potencial de crecimiento de gramíneas templadas perennes durante la estación fría del año. En dos cultivares de L. perenne y dos de B. stamineus se analizaron variables asociadas al crecimiento individual, la capacidad de macollaje y la precocidad reproductiva con el objeto de entender los principales mecanismos involucrados en la superior capacidad productiva invernal de B. stamineus. En macollos individuales se estimó: la tasa de elongación foliar (TEFM), la longitud de  pseudotallo, el filocrono, el número de hojas vivas y en crecimiento, la aparición de macollos hijos y los macollos con hoja bandera. Finalmente, se estimó la densidad de macollos por unidad de superficie. Bromus stamineus mostró mayor TEFM que L. perenne y esto se asoció positivamente con su mayor precocidad reproductiva, estimada a partir del momento en que comienza la elongación del pseudotallo. Contrariamente a lo esperado, la especie con menor valor de filocrono (B. stamineus) presentó menor densidad de macollos, y esto se asoció a una menor relación entre los macollos y hojas aparecidas (MAP\/HAP) y a una mayor TEFM. La asociación positiva entre crecimiento individual y precocidad reproductiva sugiere que la mayor productividad invernal de B. stamineus estaría explicada por el estatus fisiológico (i.e. ápice inducido\/reproductivo) de los individuos que forman su canopia durante el período invernal, lo que le conferiría características más favorables para la producción de forraje (i.e. mayor capacidad fotosintética y mayor partición hacia órganos aéreos) durante dicho período de bajas temperaturas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238178,"idioma_id":4,"titulo":"Odonata from La Pampa province, Argentina","resumen":"In Argentina approximately 280 odonate species have been recorded, which are chiefly found in the north-eastern and north-western regions. With only three previously recorded species, La Pampa province is one of most understudied parts of the country. In the present work we provide a check-list of 17 species from La Pampa, including 14 new records for the province.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238180,"idioma_id":5,"titulo":"EDAD Y NATURALEZA DEL MAGMATISMO BÁSICO EOCENO DE LOS ALREDEDORES DE LA MESETA DEL CANQUEL","resumen":"En el norte de la meseta de Canquel, entre Paso de Indios y Las Plumas, afloran cuerpos intrusivos y restos de coladas de composiciónbásica alcalina cuyas dataciones previas abarcan un lapso comprendido entre 40 y 52 Ma. En esta contribución se presentan los resultados de análisis químicos de algunos de estos cuerpos junto con cuatro nuevas dataciones 39Ar\/40Ar que permiten acotar el período magmático al Ypresiano (Eoceno inferior). Las características químicas indican que los magmas son compatibles con basaltos de tipo OIB que responderían a un bajo porcentaje de fusión parcial (2%) de una misma peridotita granatífera anhidra, localizada en el manto astenosférico a una profundidad mayor a 70 km. La ausencia de evidencias de contaminación cortical indicaun ascenso rápido a través de la corteza que implica un ambiente extensional para el emplazamiento de los cuerpos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238181,"idioma_id":4,"titulo":"Linear and non Linear Trends for Seasonal NO2 and So2 concentrations in the Southern Hemisphere (2004-2016)","resumen":"In order to address the behaviour of nitrogen dioxide (NO2) and sulphur dioxide (SO2) in the context of a changing climate, linear and non-linear trends for the concentrations of these two trace gases were estimated over their seasonal standardised variables in the Southern Hemisphere?between the Equator and 60° S?using data retrieved by the Ozone Monitoring Instrument, for the period 2004?2016. A rescaling was applied to the calculated linear trends so that they are expressed in Dobson units (DU) per decade. Separately, the existence of monotonic -not necessarily linear- trends was addressed by means of the Mann-Kendall test. Results indicate that the SO2 exhibits significant linear trends in the planetary boundary layer only; they are present in all the analysed seasons but just in a small number of grid cells that are generally located over the landmasses or close to them. The SO2 concentrations in the quarterly time series exhibit, on average, a linear trend that is just below 0.08 DU decade&#8722;1 when significant and not significant values are considered altogether, but this figure increases to 0.80 DU decade&#8722;1 when only the significant trends are included. On the other hand, an important number of pixels in the lower troposphere, the middle troposphere, and the lower stratosphere have significant monotonic upward or downward trends. As for the NO2, no significant linear trends were found either in the troposphere or in the stratosphere, yet monotonic upward and downward trends were observed in the former and latter layers, respectively. Unlike the linear trends, semi-linear and non-linear trends were seen over the continents and in remote regions over the oceans. This suggests that pollutants are transported away from their sources by large-scale circulation and redistributed hemispherically. The combination of regional meteorological phenomena with atmospheric chemistry was raised as a possible explanation for the observed trends. If extrapolated, these trends are in an overall contradiction with the projected emissions of both gases for the current century.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238182,"idioma_id":4,"titulo":"Ripe banana flour as a source of antioxidants in layer and sponge cakes","resumen":"About one-fifth of all bananas harvested become culls that are normally disposed of improperly. However, ripe banana pulp contains significant amounts of fibre and polyphenol compounds as well as a high content of simple sugars (61.06g\/100g),making it suitable for sucrose replacement in bakery products. This work studies the feasibility of incorporating ripe banana flour (20 and 40% of replacement) in cake formulation. Physical, nutritional and sensory attributes of sponge and layer cakes are evaluated. The inclusion of ripe banana flour generally led to an increased batter consistency that hindered cake expansion, resulting in a slightly lower specific volume and higher hardness. This effect was minimised in layer cakes where differences in volume were only evident with the higher level of replacement. The lower volume and higher hardness contributed to the decline of the acceptability observed in the sensory test. Unlike physical attributes, the banana flour inclusion significantly improved the nutritional properties of the cakes, bringing about an enhancement in dietary fibre,polyphenols and antioxidant capacity (up to a threefold improvement in antioxidant capacity performance). Therefore, results showed that sugar replacement by ripe banana flour enhanced nutritional enhancement of cakes, but attention should be paid to its inclusion level.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238183,"idioma_id":4,"titulo":"Paleo-climatic and paleo-environmental evolution of the Neoproterozoic basal sedimentary cover on the Río de La Plata Craton, Argentina: Insights from the &#948;13C chemostratigraphy","resumen":"The Sierras Bayas Group of the Tandilia System constitutes the Neoproterozoic sedimentary cover of the Río de La Plata Craton in Argentina that accumulated amid the breakup of the Rodinia supercontinent and subsequent assembly of Gondwanaland. Evidence for glaciation in the Villa Mónica Formation (VMF) at the base of the succession comes in the form of iron-rich laminated sediments containing dropstones composed predominantly of basement crystalline rocks and quartzites that, are sequentially overlain by a phosphatic mudstone and a ~ 40 m thick stromatolitic dolomite. Subtidal facies preserve columnar forms similar to post-glacial tubestone stromatolites seen in the Neoproterozoic records. These morphologies suggest rapid growth associated with elevated seawater alkalinity and high rates of carbonate accumulation records. The VMF dolomites in our four studied sections near Olavarría-Sierras Bayas area reveal a pronounced negative-to-positive &#948;13C up section that is similarly to these cap carbonates and others worldwide. Our sedimentological and geochemical study of the VMF sections reveal consistent carbon and oxygen isotope trends that may be useful for detailed intra-basinal correlations. Samples of the VMF fabric-retentive dolomite preserve an unusually narrow range of non-radiogenic strontium isotopic compositions (0.7068 to 0.7070) that are consistent with Cryogenian limestone facies in the potential Namibian and Brazilian equivalents. Exceptional preservation of 87Sr\/86Sr compositions suggest the possibility of primary dolomite precipitation in post-glacial seawater, and furthermore that REE patterns and distributions may yield similar insights to redox conditions in the depositional basin. In particular, the VMF dolomites reveal depleted LREE abundances, a negative Ce anomaly, positive La and Gd anomalies, and low Y\/Ho values. As a whole, these observations suggest oxidizing post-glacial seawater conditions associated with significant freshwater inputs into the basin. Global warming and increases in primary productivity and organic carbon burial linked to the buildup of oxygen, the positive &#948;13C trend and the increase in stromatolite biodiversity in the VMF.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238184,"idioma_id":4,"titulo":"Tectonic evolution of the Neoproterozoic Tandilia sedimentary cover, Argentina: New evidence of contraction and extensional events in the southwest Gondwana margin","resumen":"At the northwestern portion of the Tandilia System, a detailed structural analysis on the Precambrian sedimentary units exposed in the quarries of the Olavarría-Sierras Bayas area was carried out. These units exhibit deformational structures of several scales, from centimeters to hundreds of meters. The hundreds of meters scale involves E-W- and NW-SE-trending normal faults and NW-SE- and NE-SW-trending contractional folds. The centimeters to meters scale involves veins, joints, normal faults, shear fractures and stylolites, with a prevailing &#8764; E-W to NW-SE trend. All these structures were formed by two major tectonic events. The first was the folding event at &#8764;580 Ma, with NNE-SSW to NE-SW and NW-SE direction of contraction. The second was the extensional faulting event, given by the widespread NNE-SSW-directed extension event during the Atlantic Ocean opening (Jurassic-Cretaceous). Both major events would have been controlled by the reactivation of basement anisotropies. These major tectonic events controlled the deformation of the Precambrian sedimentary cover of the Tandilia system, leading to an economically important aspect in the mining development of the Olavarría-Sierras Bayas area.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238186,"idioma_id":4,"titulo":"Simultaneous Cr(VI) and lindane removal by Streptomyces M7 is improved by maize root exudates","resumen":"Simultaneous Cr(VI) and lindane removal by Streptomyces M7 is improved by maize root exudates","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238188,"idioma_id":4,"titulo":"Control System to Balance Internal Currents of a Multilevel Current-Source Inverter","resumen":"In this paper, a Model Predictive Control (MPC)strategy is applied to a Multilevel Current Source Inverter(MCSI) and its associated current source. The controller usesa discrete-time model of the entire system in order to predictthe future behavior for each of the available switch states. Thesystem is composed of a multilevel inverter, a buck converter, anoutput filter and a load. Each of the calculated values is used tominimize a set of predefined control objectives within a multitermcost function. It includes costs associated with the switchingfrequency and reference tracking. This allows to control not onlythe output voltages of the load, but also the current source andthe balance of the internal currents of the inverter. Simulationresults show a good performance and fast dynamics with a lowswitching frequency of all the switches involved. These featuresmake the proposed controller a suitable option for use with highpower converters.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238189,"idioma_id":4,"titulo":"Training small producers in Good Manufacturing Practices for the development of goat milk cheese","resumen":"AbstractTraining in Good Manufacturing Practices enhances quality during food processing. This paper evaluates GMP training aimed at improving the chemical, sensory and microbiological quality of goat milk cheese. We worked with 26 families that produce cheese as their main source of income. Semi-structured interviews and observation were conducted to select relevant topics. The manufacturing processes were compared and samples were analyzed before and after GMP training. We trained 80% of the producers. Before receiving training, they used to make cheese from raw milk in unhygienic conditions and with little equipment. The products obtained had bad sensory characteristics, cracks, eyes on the pasta, a high number of aerobic mesophilic bacteria and total coliforms. After training, the producers pasteurized the milk and standardized processing procedures, resulting in final products that contained higher protein and calcium content, suitable sensory characteristics, and a significant reduction in microorganisms, with total coliforms falling to &#8804; 5.103UFC\/g. Therefore, this study shows that the manufacturing process and the chemical, sensory and microbiological parameters of goat milk cheese improved after GMP training.Keywords:cheese; goat milk; Good Manufacturing Practices.Practical Application:Enhance the manufacturing conditions in terms of nutrition, sensory characteristics, and hygiene.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238190,"idioma_id":4,"titulo":"A new method using Scanning Electron Microscopy (SEM) for preparation of anisopterous odonates","resumen":"Anisopterous odonate male?s secondary genitalia is a complex of several structures, among themthe vesica spermalis is the most informative with important specific characters. The observation ofthose characters, mostly of membranous nature, is difficult in the Scanning Electron Microscopedue to dehydration and metallization processes. In this contribution, we discuss a new and lowcost procedure for the observation of these characters in the SEM, compatible with the most commonagents used for preserving specimens.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238192,"idioma_id":4,"titulo":"Crop-wild sunflower hybridization can mediate weediness throughout growth-stress tolerance trade-offs","resumen":"Agricultural weeds are plants well-adapted to agricultural environments interfering directly and indirectly with crop production and causing important economic losses worldwide. Crop-wild hybridization is one of the main forces that have ruled weed evolution along with adaptation to agricultural (or benign) environments. Considering the competing demands for resources in any plant, adaptation to agricultural environments might result in an increase in growth but with lower tolerance to stress. In Argentina, most of the non-native H. annuus populations grow on roadsides, ditches, fences, hedgerows (ruderals), but there are also a few cases of H. annuus growing in agricultural field as weeds (agrestals). We asume that weediness of these agrestal biotypes came after crop hybridization as result of growth-stress tolerance trade-offs. Ruderal, agrestal (with evidence of crop introgression), and crop biotypes were contrasted under studies of drought and defoliation stresses, as well as for plant growth under non-stressful conditions and sequences of stress-related genes. The agrestal biotype was less tolerant to defoliation and drought than the ruderal biotype. Drought tolerance variation was largely explained by plant height rate (growth) and defoliation tolerance variation was mainly explained by biomass accumulation (resource allocation). Agrestal biotype sequences of two genes encoding transcription factors involved in stress response, DREB2 and NAC, showed evidence of positive selection in the crop direction. Therefore, selection in the agricultural environment combined with crop hybridization driver the evolution of a well-adapted genetic variant of H. annuus with fast growth but reduced stress tolerance.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238193,"idioma_id":4,"titulo":"Response of Digitaria insularis seed germination to environmental factors.","resumen":"Digitaria insularis became a weed problem in agricultural fields from the north-central region of Argentina and was reported as resistant to herbicides in some of the neighbouring countries. A better understanding of the germination ecology of local biotypes of D. insularis could help to reduce the colonization and invasion and thus, to improve the long-term management strategies for this weed. The objective of this work was to study the effect of environmental factors on germination of D. insularis seeds from two different populations of Argentina. Three experiments were performed in germination chambers using recently dispersed seeds. No differences were observed on germination between seeds with or without pre-chilling treatments, suggesting an initial low dormancy level. Independently of the origin of the seeds and light treatments, germination at constant 25°C was lower than germination at fluctuating 20\/35°C. At constant temperatures germination was higher for seeds from Santiago del Estero than from Cordoba and as the number of hydration-dehydration cycles increased and germination was reduced with exposition to far red light during one hour. Fluctuating temperatures of 20\/35°C reduced the sensibility to all the other factors evaluated, such as, hydration-dehydration cycles and light quality, even seed origin. Any crop management decision that includes the reduction of soil thermal fluctuations and\/or far red: red ratio (such as stubble, cover crops, etc.), could reduce seedling field emergence.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238194,"idioma_id":4,"titulo":"Characterization of an artisanal fishery in Argentina using the social-ecological systems framework","resumen":"Institutional Analysis and Development (IAD) studies how institutions(the rules of the game of a society) determine the performance of a social-economicsystem. Elinor Ostrom extends the institutional analysis to the collectiveaction for a particular case, the study of the social-ecological systems (SESs)(Ostrom 1990). Any group that attempts to manage a common resource (e.g. aquifers,pastures) for optimal sustainable production must solve a set of problems inorder to create institutions to facilitate collective action. Some evidences showthat following a set of design principles in creating institutions can lead to overcomethese problems. The aim of the paper is to apply the SES framework to anartisanal fishery community in Argentina in order to: 1) describe the principalfeatures, key variables and relations of the small-scale fishery system; 2) detectthe principal drivers of a potential common-management and the leading detractorsfrom the current communal performance; and 3) analyze the possibility thata self-governing for sustainable fishery may appear. Several drivers for potentialcommon-management and some detractors from the current common performanceare summarized. Artisanal fishery SES is currently at a bifurcation point.A common historical and cultural root, the presence of leaderships, the relevanceof local knowledge, the dependence on the resource to sustainable livelihoodsand the threat of big-scale fisheries area have generated incentives to collectiveaction.But, simultaneously, internal conflicts are the most important barrier for anintegrated community-based management. The heterogeneity among actors andthe relevant external conditions have resulted in two groups diverging in theirself-organization. The work is framed by the project COMET-LA (COmmunitybasedManagement of Environmental challenges in Latin America; EuropeanCommission?s Seventh Framework Programme of Research and Development),which aims to identify sustainable community-based governance for the managementof natural resources that can be used in different social-ecological systemsin a context of climate change and increasing competition in the use of resources.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238195,"idioma_id":5,"titulo":"Monitoreo de glifosato en agua superficial en Entre Ríos. La investigación acción participativa como metodología de abordaje","resumen":"There is concern about glyphosate losses from agroecosystems and its impact on surface water in urbanand rural communities of Entre Rios, having a widespread perception of risk in public opinion. Social awarenesswas exacerbated by lack of information, which requires an adequate approach. The objectives were: i) toset up a network for monitoring the effect of glyphosate use on water quality (RMCA) in the agricultural area ofEntre Rios, ii) to estimate glyphosate concentration in surface water as a result of losses from the agroecosystem,and iii) to identify management practices of low environmental impact to be agreed on with membersof the agro alimentary sector. The methodological framework applied corresponds to a Participatory ActionResearch (PAR) approach. An awareness program for professionals, farmers and organizations interested inknowing water quality was carried out. Site selection and water sampling were carried out by RMCA members.A schedule of 3 sampling periods was established: 1º) August 15th - September 15th 2012, 2º) November15th - December 15th 2012 and 3º) March 15th - April 15th 2013. Concentration of glyphosate in the watersamples was determined by the Elisa technique, using as a UPLC-MS\/MS verification method. Glyphosateconcentrations were classified according to the guide levels defined by the Undersecreatriat of Water Resourcesof Argentina and the European Union: < 0.1 &#956;g L-1; 0.1-240 &#956;g L-1 y &#707; 240 &#956;g L-1. The RMCA network wasintegrated by 70 members becoming a community-based organization to promote the preservation of surfacewater. 311 monitoring points and 703 water samples were evaluated. In the first period, 4.7% of the monitoringpoints overcame the level of 240 &#956;g L-1 whereas in the second sampling instance all concentrations resultswere lower, 69% of them showing values below 0.1 &#956;g L-1. 76% of the March-April samples resulted in concentrationsbelow 0.1 &#956;g L-1. Results were discussed by RCMA members in a workshop that was replicated at4 locations. In a second meeting, the members identified on agronomic practices of environmental low impact.The PAR proved to be an adequate methodology to analyze changes in the quality of surface water due to theuse of glyphosate in the agricultural area of Entre Rios. The quantification of glyphosate concentration in waterallowed to know the risk of pollution, not previously measured, which promoted the search for consensualsolutions among stakeholders of the agro alimentary sector to either mitigate or solve environmental impactby the use of agrochemicals.Keywords: Entre Ríos, surface water","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238197,"idioma_id":4,"titulo":"Role of seed environment and covering structures on large crabgrass germination","resumen":"The success of large crabgrass (Digitaria sanguinalis) growing among summer crops in Argentina, may be partly explained by its escape fromweed controls related to theemergence of different seedlings cohorts determined by seed dormancy and germination requirements. The objectives of thiswork were to evaluate the effect of temperature,red (R):far-red (FR) ratio and the possible role of the caryopses covering structures on the release of seed dormancy in D. sanguinalis. Therefore, the effects of moist pre-treatment duration, light and temperature, as well as the caryopsis covering structures, and imbibition with H2O2 and the extract of caryopses covers on seed germination, were investigated. Moist pre-treatment at 5 and 20 °C promoted dormancy release and fluctuatingtemperatures between 20\/30 °C and light promoted germination. However, exposure to 30 min of light with a high R:FR ratio reduced germination. Removing or puncturing some of the caryopsis covering structures, as well as imbibitionwith 2.6MH2O2 enhanced seed germination. Results suggest that the extended seedling emergence throughout the season could be due to the influence of the environmental factors studied here on dormancy release and germination, and that seed covering structures have an important role in seed dormancy imposition for this species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238200,"idioma_id":4,"titulo":"A new method using Scanning Electron Microscopy (SEM) for preparation of anisopterous odonates","resumen":"Anisopterous odonate male?s secondary genitalia is a complex of several structures, among them the vesica spermalis is the most informative with important specific characters. The observation of those characters, mostly of membranous nature, is difficult in the Scanning Electron Microscope due to dehydration and metallization processes. In this contribution, we discuss a new and low cost procedure for the observation of these characters in the SEM, compatible with the most common agents used for preserving specimens.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238202,"idioma_id":5,"titulo":"Biografías escolares de docentes noveles del Profesorado de Inglés: la dimensión profesional y la práctica artesanal.","resumen":"El caudal de estudios que busca ahon- dar en los caminos de la docencia para desanudar sus laberintos es abarcativo y creciente. Desde hace más de un siglo hemos estado buscando el sentido del o cio de enseñar tratando de de nir la profesión docente desde distintos abordajes. Por su parte, el sociólogo es- tadounidense Richard Sennett (2009) ha trazado una línea de indagación que busca entender la docencia como una labor artesanal. El autor explica que la artesanía es la habilidad de hacer las co- sas bien y está activada por un impulso humano duradero y básico: el deseo de realizar adecuadamente una tarea. Ser un artesano implica, en un sentido más amplio, un continuo monitoreo de las propias prácticas al servicio del crecimiento y el desarrollo profesional. Convertirnos en artesanos de nuestra propia obra, comprometidos con lo que hacemos, nos acerca a aquellos con quienes trabajamos a la vez que ?nos proyecta hacia la humanidad que contribuimos a eternizar, porque ele- gimos hacerlo? (Alliaud, 2017, p. 15). Buscamos aquí explorar la dimensión profesional de la biografía escolar de docentes noveles del Profesorado de Inglés de la Universidad Nacional de Mar del Plata y así a trazar un camino que nos permita visualizar las prácticas de los profesores universitarios en un marco particular, el de la artesanía.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238211,"idioma_id":5,"titulo":"INDICE AGROAMBIENTAL PARA LA EVALUACION DEL IMPACTO POR CAMBIO DE USO DEL SUELO A NIVEL PREDIAL EN AGROECOSISTEMAS DEL ESPINAL ENTRERRIANO","resumen":"El objetivo fue desarrollar un índice agroambiental (IAG) integrando indicadores de calidad de suelo (ICS) y vegetación (ICV) para evaluar el impacto por cambio de uso del suelo en áreas de bosques nativos, a nivel predial, en Entre Ríos. Se evaluaron tres agroecosistemas: bosque estable con pastoreo (BE), renoval (REN), y agricultura (AGR) en Argiudoles y Hapludertes. Se utilizaron ICS definidos por la bibliografía cuantificándose a partir de bases de datos y bibliografía, sumado a la determinación a campo del carbono de la biomasa microbiana (CBM) para Argiudoles. Se seleccionaron cinco ICV y se cuantificaron mediante relevamientos de vegetación a campo. El IAG se elaboró aplicando el marco de la Técnica Mixta MESMIS, determinándose valores de referencia, umbrales y escalas nominales para los ICV; y escalas de Calidad Agroambiental para ambos suelos. El BE fue el de mayor IAG clasificándose como de Muy Buena Calidad Agroambiental, reflejando una condición de producción sustentable en los dos suelos evaluados. Le siguió REN; de Buena Calidad en Argiudoles y Regular en Hapludertes, detectándose impactos en la estructura arbórea y la presencia de malezas invasoras en el pastizal. El AGR resultó de muy bajo IAG en Argiudoles y bajo en Vertisol, requiriéndose la incorporación de técnicas para la recuperación de ICS e ICV. El IAG resultó de utilidad para evaluar el impacto del cambio de uso del suelo en los agroecosistemas a nivel predial; identificando las variaciones de calidad en los ICS e ICV y permitiendo el análisis de propuestas de manejo sustentable.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238213,"idioma_id":5,"titulo":"Tratamiento de la pareja infértil: creación de un servicio de fertilidad en el Instituto de Maternidad de Tucumán","resumen":"En el artículo se evalúa el funcionamiento del Servicio de Fertilidad desde su creación en 2013, empleando la técnica del Análisis de las Fortalezas, Oportunidades, Debilidades y Amenazas (FODA). Asimismo, se caracteriza la población a la cual está destinado este esfuerzo sin precedentes a nivel provincial y regional.En Medicina Reproductiva, es esencial contar con un sistema público que asegure calidad, oportunidad e integralidad de la atención.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238214,"idioma_id":5,"titulo":"?Multimodalidad, género y política. Cristina Fernández de Kirchner en Noticias?","resumen":"Análisis de representaciones de género de la figura presidencial de Cristina Fernández de Kirchner en Tapas de&nbsp; Revista Noticias durante su mandato 2011-2015 desde la perspectiva multimodal y de Análisis Crítico del Discurso.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238215,"idioma_id":5,"titulo":"La construcción discursiva de la catástrofe: representaciones en torno a la inundación de Santa Fe?","resumen":"Análisis de las representaciones y estrategias discursivas utilizadas por la prensa gráfica en la construcción&nbsp; de la inundación de 2003 en Santa Fe como catástrofe natural en el diario local.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238217,"idioma_id":4,"titulo":"Low intensity, continuous wave photodoping of ZnO quantum dots ? photon energy and particle size effects","resumen":"The unique properties of semiconductor quantum dots (QDs) have found application in the conversion of solar to chemical energy. How the relative rates of the redox processes that control QD photon efficiencies depend on the particle radius (r) and photon energy (El), however, is not fully understood.Here, we address these issues and report the quantum yields (Fs) of interfacial charge transfer and electron doping in ZnO QDs capped with ethylene glycol (EG) as a function of r and El in the presence and absence of methyl viologen (MV2+) as an electron acceptor, respectively. We found that Fs for the oxidation of EG are independent of E l and photon fluence (jl ), but markedly increase with r. The independence of Fs on jl ensures that QDs are never populated by more than one electron-hole pair, thereby excluding Auger-type terminations. We show that these findings are consistent with the operation of an interfacial redox process that involves thermalized carriers in the Marcus inverted region. In the absence of MV2+, QDs accumulate electrons up to limiting volumetric densities r e,N that depend sigmoidally on excess photon energy E*= El-BG(r), where E BG(r) is the r-dependent bandgap energy. The maximum electron densities: pev,(inf)= 4x10^20 cm^-3 , are reached at E*>0.5 eV, independent of the particle radius.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238218,"idioma_id":5,"titulo":"SELECCIÓN DE CEPAS DE Trichoderma spp. TOLERANTES AL ARSÉNICO Y CON CAPACIDAD DE REMOCIÓN EN MEDIO LÍQUIDO","resumen":"En este trabajo se seleccionó cepas de Trichoderma spp. con capacidad de tolerar y remover arsénico (As). Lametodología utilizada para las pruebas de tolerancia fue la exposición a 500 y1000 mg L-1 de As(III) en medio sólido. El estudio de remoción de As se realizó en medio líquido,cuantificando la concentración de As mediante espectrometría de absorción atómica con generación dehidruros. Los resultados obtenidos indican que de las 4 cepas de Trichoderma spp. bajo estudio las cepas T4R3 y T01 mostraron los menores &nbsp;porcentajes de inhibición 20,2% y 18,7% a 500mg L-1 y 4,1% y 8,7% a 1000 mg L-1 respectivamente a las24 h de cultivo. Estas mismas cepas presentaron los mayores índices detolerancia con valores de 0,80 a 0,93 a las 24 h de cultivo. En medio líquidocon 1,44 mg L-1 de As las cepas que presentaron mayor crecimiento fueronMai y T4R3 con 3,63 y 3,88 g L-1 respectivamente. La que mostrómayor efectividad en la remoción de As luego de 72 h de exposición fue la cepaT1R3 con 40,52%. Estos resultados demuestran el potencial de la cepa T1R3 paraser utilizada en estudios de mitigación del As.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238219,"idioma_id":4,"titulo":"Cu2O\/TiO2 heterostructures for CO2 reduction through a direct Z-scheme: Protecting Cu2O from photocorrosion","resumen":"The development of artificial photosynthesis aims to solve the increasing energy demand and associated environmental problems. A model photosynthetic system employing a composite of semiconductors with a Z-scheme can potentially mimic the combined power of photosystems 1 and 2 to transfer electrons. In this work, octahedral cuprous oxide covered with titanium dioxide nanoparticles (Cu2O\/TiO2) are synthesized by a solvothermal strategy that provides high morphological and crystallographic control. The formation of a p-n heterojunction and characterization of the Type II band alignment of the composite are performed by diffuse reflectance UV-visible (DRUV) spectroscopy, ultraviolet photoelectron spectroscopy (UPS), and X-ray photoelectron spectroscopy (XPS). Upon UV-visible irradiation (&#955; &#8805; 305 nm) of the composite in the presence of water vapor as the hole scavenger, the photoreduction of CO2(g) proceeds selectively to generate CO(g). The production rate of CO by the composite, RCO = 2.11 &#956;mol gcat &#8722;1 h&#8722;1, is 4-times larger than for pure Cu2O under identical conditions. Contrasting XPS analyses of Cu2O and Cu2O\/TiO2, during photocatalysts operation and the detection of photogenerated hydroxyl radicals (HO[rad]) in the heterostructure at variance with the results obtained for pure Cu2O are taken as evidences that TiO2 protects Cu2O from undergoing photocorrosion. These results provide direct evidence of an efficient Z-scheme as the main mechanism for harvesting energy during CO2 reduction in the synthesized materials.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238221,"idioma_id":5,"titulo":"Rafael Iglesia. El último provocador","resumen":"Rafael Iglesia, el último provocador, trata sobre la vida profesional y de sus obras mas relevantes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238222,"idioma_id":5,"titulo":"RCR Arquitectes. El Premio Pritzker y la Arquitectura Glocal","resumen":"El articulo explora tanto la obra de los arquitectos premiados como así también las lógicas implícitas tras los Premios de Arquitectura, especialmente el premio Pritzker.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238224,"idioma_id":5,"titulo":"Selección de cepas de Trichoderma spp. tolerantes al arsénico y con capacidad de remoción en medio liquido","resumen":"Selección de cepas de Trichoderma spp. tolerantes al Arsénico y con capacidad de remoción en medio líquido","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238227,"idioma_id":5,"titulo":"Historia y memoria a doscientos años de la Declaración de la Independencia: espacios, lugares y acontecimientos","resumen":"En el presente artículo se desarrolla la introducción al dossier ?Historia y memoria a doscientos años de la Declaración de la Independencia: espacios, lugares y acontecimientos?, correspondiente al número 17 de la revista Estudios del ISHIR. En el mismo se recorre el contexto y las condiciones de producción de los artículos que integran el mismo, gestados en principio en el Encuentro ?Historia y Memoria. En torno al Bicentenario de la Independencia Argentina?. En esta presentación se atiende a las líneas de investigación y categorías vinculadas a los debates en torno a las problemáticas sobre la construcción de la nación y las implicaciones de la historia y la memoria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238228,"idioma_id":5,"titulo":"La Declaración de la Independencia. Memorias, discursos y antiperonismo en Jujuy, 1956","resumen":"El objetivo del presente artículo supone determinar las características del discurso oficial en homenaje a la Declaración de la Independencia en la provincia de Jujuy durante la Revolución Libertadora. En este sentido se establecen las líneas dominantes del discurso oficial, basadas en rechazar las narraciones sobre el pasado instaurado por el peronismo y en reconstituir la memoria de los acontecimientos de la historia argentina. La interpretación planteada supone que en este contexto el gobierno provincial promovió una nueva significación de la Declaración de la Independencia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238229,"idioma_id":5,"titulo":"Connivencia y oposición: la Unión Cívica Radical frente al gobierno peronista, Jujuy, Argentina (1952-1955)","resumen":"El presente artículo tiene como objetivo establecer las peculiaridades y las condiciones de producción de las prácticas y discursos delineadas por la Unión Cívica Radical (UCR) frente a las políticas socioeconómicas fomentadas por el gobierno peronista en el marco de la provincia de Jujuy (ubicada en el noroeste de la Argentina) durante la primera mitad de la década de 1950.  En este sentido, se reseña las características regionales, la tradición partidaria, las deliberaciones llevadas a cabo en el  contexto de la legislatura y diversos posicionamientos asumidos por la UCR. Sobre los resultados de este trabajo, cabe señalar que esta organización fundó sus prácticas y discursos en función de sus principios yrigoyenistas, de corte popular, que favoreció complicidades y antagonismos con el gobierno peronista.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238233,"idioma_id":5,"titulo":"Manejo de la fertilización en el cultivo trigo en un lote con ambientes productivos diferenciados a través de imágenes. Campaña 2016.","resumen":"En los últimos años se han adoptado tecnologías de insumos y de procesos en losprincipales cultivos extensivos de la región centro, lo que permitió plantear diferentes manejos para potenciar y eficientizar el uso de los recursos disponibles. En la actualidad, con herramientas de teledetección, datos Georeferenciados y uso de sistemas de información geográfico es posible generar estrategias productivas basadas en manejos por sitio específico (MSI). Dentro de un mismo lote hay sectores que ofrecen condiciones particulares que tienenque ver con las propiedades fisicoquímicas de suelo, manejos diferentes en uso, secuencia de cultivos a lo largo del tiempo y aportes de agua subterránea entre otras. Esto puede reflejarse sobre los cultivos, manifestándose como diferencias en crecimiento y desarrollo que pueden o no incidir a nivel del rendimiento de grano. El manejo de la nutrición en trigo a través delagregado de fertilizantes químicos considerando la heterogeneidad del lote, puede resultar en un factor de mejora sobre la condición general del cultivo. Con el objetivo de interpretar a través de imágenes satelitales y capturas por dron, se hizo un trabajo de campo integrando metodologías de muestreo para evaluar distintas variables que pudiesen explicar las respuestas observadas en el cultivo al agregado de fertilizante líquido compuesto de nitrógenoy azufre en dosis crecientes. Se buscó así finalmente aplicar nuevas tecnologías con análisis de imágenes, para interpretar lo que ocurre sobre un cultivo de trigo implantado en un lote con influencia de napas y con características edáficas y de manejo que le son propias. La cuantificación de las variables ayudó a explicar diferencias en rendimiento de grano medido a través de monitor de rendimiento.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238235,"idioma_id":4,"titulo":"Tautomerism of uracil and related compounds: a mass spectrometry study","resumen":"It has been demonstrated that uracil has a preponderant tautomeric form, but it is also known that different tautomers co-exist in this equilibrium. In this work, mass spectrometry is used as a helpful tool to analyze the equilibria, using derivative compounds to forbid the presence of some tautomers and ion trap mass spectrometry to follow relevant fragmentation pathways. Theoretical calculations were performed to confirm tautomers abundance by energy minimization in gas phase. Analysis of mass spectra of uracil, three methyl-substituted uracils, 2-thiouracil and three benzouracils suggest that uracil exists mainly as three tautomers in gas phase: one major structure that corresponds to the classical structure of uracil (pyrimidine-2,4(1H,3H)-dione) bearing two carbonyls and two NH moieties, and two minor enolic forms (4-hydroxypyrimidin-2(1H)-one and 2-hydroxypyrimidin-4(1H)-one). Such tautomeric distribution is supported by theoretical calculations, which show that they are the three most stable tautomers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238236,"idioma_id":5,"titulo":"Campaña de trigo 2016: Evolución de las variables agrometeorológicas medidas en la estación convencional de la EEA INTA Marcos Juárez","resumen":"El clima es un recurso natural que afecta a la producción agraria. Su influencia en un cultivo determinado no depende sólo de las características climáticas de la localidad en que esté situado, sino también en gran medida de las condiciones en que se desarrolla la producción. Así, tiene tanta importancia el nivel de exposición del cultivo al clima como el nivel de vulnerabilidad.Este informe tiene como objetivo presentar los valores actualizados de variablesmeteorológicas tales como: precipitaciones, nivel freático , temperatura ambiente, heliofanía efectiva, humedad relativa ambiente y evapotranspiración potencial desde abril hasta noviembre de 2016 en comparación con registros históricos tomados en la estación meteorológica convencional de la EEA INTA Marcos Juárez correspondientes al período (1960-2015), la misma forma parte de la Red de Estaciones Agrometeorológicas del INTA y de la Red Oficial del Servicio Meteorológico Nacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238237,"idioma_id":5,"titulo":"Los huesos de guanaco pintados de Cueva Huenul 1 (norte del Neuquén, Patagonia septentrional)","resumen":"El objetivo de esta nota es presentar una caracterización detallada de dos huesos de guanaco pintados recuperados durante la excavación de Cueva Huenul 1 (CH1), ubicada en el norte de la provincia del Neuquén (Departamento Pehuenches), en Patagonia septentrional (Figura 1). Estos fueron recuperados en el marco de un proyecto regional de corte biogeográfico orientado a evaluar las pautas de conducta y distribución espacio-temporal de las poblaciones humanas que ocuparon la región, con foco en el Holoceno tardío (Barberena 2013).Una línea de investigación clave dentro del mismo consiste en caracterizar la dinámica de circulación de información implementada, en distintas escalas espaciales, por los grupos humanos que habitaron la región. Para ello, se desarrolló una metodología que integra el análisis de múltiples tipos de imágenes visuales presentes en el registro arqueológico del área, sumado a otros indicadores relativos a la problemática común de la comunicación visual (Romero y Barberena 2015).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238238,"idioma_id":4,"titulo":"Differential effect of acute iron overload on oxidative status and antioxidant content in regions of rat brain","resumen":"The hypothesis of this study is that the cerebral cortex, hippocampus and striatum of the ratbrain are differentially affected in terms of oxidative stress and antioxidant capacity by acute Feoverload because Fe is distributed in a heterogeneous fashion among different regions and cells of thebrain. The effects on the lipophilic and hydrophilic cellular environment were compared betweenregions and with the whole brain. A single dose of Fe-dextran increased Fe deposits, reaching amaximum after 6 hr. Both in whole brain and in cortex region, the ascorbyl\/ascorbate content ratio wasincreased after 6 hr of Fe administration, while in striatum and hippocampus there was no significantchanges after Fe overload. Total thiol content decreased in whole brain and cortex, while in striatumand hippocampus there were no significant changes after Fe overload. The content of &#945;-tocopherol (&#945;-T) whether measured in the whole brain or in the isolated regions, did not change following Fetreatment. Lipid radical generation rate (LR&#9679;) after Fe-dextran overload only increased in the cortexregion. The LR&#9679;\/&#945;-T content ratio was increased by Fe treatment in cortex but not in the whole brain,striatum or hippocampus, in agreement with the study tested hypothesis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238240,"idioma_id":4,"titulo":"Monolithic reactor for VOCs abatement: Influence of non-uniformity in the coating","resumen":"This article presents a theoretical study of the catalytic mineralisation of ethanol via acetaldehyde over manganese - copper mixed oxide catalyst deposited on a monolith reactor. The steady-state operation of the monolith reactor is represented by means a heterogeneous, one-dimensional, adiabatic model, which accounts for external (gas-solid) resistances to mass and heat transfer and internal resistances to mass transfer inside the catalytic coating (washcoat). The effect of catalyst accumulation at the corners of a square section channel is analysed. Under the operating conditions considered, the diffusional resistances have a significant effect on the effective rate of removal of Volatile Organic Compounds and cannot be neglected. Non-uniform coating causes a considerable deterioration of the averaged effectiveness factors of the two reactions under consideration and lower temperatures along the reactor are found. These lower temperatures, together with lower temperature drops over the external film cause additional negative impacts on the Volatile Organic Compounds conversion. The decrease in the reactor performance, caused by the catalyst accumulation, is magnified as the feed concentration rises. Consequently, higher feed temperatures and\/or lower space velocities are necessary to ensure the complete destruction of the volatile organic compounds involved (ethanol and acetaldehyde).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238241,"idioma_id":4,"titulo":"Comparison between WGS membrane reactors operating with and without sweep gas: Limiting conditions for co-current flow","resumen":"In this work, a comparative study is carried out to analyze the behavior of a water gas shift membrane reactor operating with and without sweep gas. The present study includes thermal effects that play a key role in reaction and permeation rates involved in the membrane reactor. Based on a 1-D mathematical model, the effect of the most important operating variables on the membrane reactor performance is comparatively studied. Additionally, novel algebraic expressions are developed when operating without sweep gas, that only depend on inlet variables to calculate the limiting membrane reactor conversions and recovery values. An algebraic equation is developed to estimate limiting recovery when operating with sweep gas. The dependence of limiting membrane reactor conversion and recovery values operating with and without sweep gas on operating parameters is included. From the comparative analysis, some guidelines for an improved operation of the membrane reactor are proposed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238243,"idioma_id":5,"titulo":"Tecnología ósea en la depresión del río Salado (provincia de Buenos Aires)","resumen":"En el humedal de la Depresión del río Salado -habitado durante el Holoceno tardío (entre 2400 y 400 años AP) por grupos de expertos alfareros- los recursos faunísticos más explotados fueron especies de porte menor como coipo, peces, aves terrestres y acuáticas. Los cérvidos fueron recursos complementarios. Estos grupos desarrollaron estrategias de aprovisionamiento y manufactura de huesos, además de incisivos de coipo, para utilizar como instrumentos. Se analizaron tecno-morfológicamente 25 piezas óseas provenientes de los sitios LG1 (n=4) y LG5 (n=21) con evidencias de formatización antrópica. Se tomaron los siguientes parámetros: elemento, tipo de fractura, dimensiones y presencia\/ausencia de huellas; asimismo se registró la incidencia de agentes y procesos tafonómicos sobre los elementos. Se identificaron varios taxa: Aves (=4), Rallidae (n=1), Mammalia (n=2), Cervidae (n=4), Ozotoceros bezoarticus (n=8), Blastoceros dichotomus (n=1), Rodentia (n=1), Rodentia cf. Caviinae (n=3) y Myocastor coypus(n=1). Se definieron los Grupos Morfológicos: tubos, biseles, puntas (ahuecada, acanalada, semiacanalada, roma) y aquellos que no pudieron asignarse a los ya definidos, se indicaron como indeterminados. Se discuten posibles funciones y se propone que esta tecnología ósea es parte del uso integral de los recursos faunísticos del área.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238244,"idioma_id":4,"titulo":"A new species of Iralunelus  &#348;tys (Hemiptera, Heteroptera: Aradidae) from the Neotropics.","resumen":"A new species of genus Iralunelus  &#348;tys, 1974: I. zipaquirensis Contreras, Neder and Coscarón sp. n. from Zipaquirá, Colombia, is described and illustrated. This new species  is close to I. sahlbergi (Bergroth, 1886)  and  I. simulans (Walker, 1873) for the presence of a callus on the scutellum and the anterolateral angles of pronotum  rounded, but can be   distinguished by the following characters: scutellum with a large rounded callus on the anterior half; conexive narrow; male  paratergites VIII rectangular with the truncated apex and located obliquely to the length of pygophore. Figures of the genitalia of the new species are provided","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238246,"idioma_id":4,"titulo":"Cr(VI) and lindane removal by Streptomyces M7 is improved by maize root exudates","resumen":"Environmental mixed pollution by both organic and inorganic compounds aredetected worldwide. Phytoremediation techniques have been proposed as ecofriendly methods for cleaning up polluted sites. Several studies have demonstrated enhanced dissipation of contaminants at the root-soil interface through an increase in microbial activity caused by the release of plant root exudates (REs). The aim of this study was to evaluate the effectiveness for Cr(VI) and lindane removal by Streptomyces M7 cultured in a co-contaminated system in presence of maize REs. Our results showed when REs were added to the contaminated minimal medium (MM) as the only carbon source, microbial removal of Cr(VI) and lindane increased significantly in comparison to contaminant removal obtained in MM with glucose 1 g L-1. The maximum removal of 91% of lindane and 49.5% of Cr(VI) were obtained in the co-contaminated system. Moreover, Streptomyces M7 showed plant growth promoting traits which could improve plant performance in contaminated soils.The results presented in this study provide evidence that maize REs improved growth of Streptomyces M7 when REs were used as a carbon source in comparison toglucose. Consequently, lindane and Cr(VI) removal was considerably enhancedmaking evident the phytoremediation potential of the actinobacteria-plant partnership.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238247,"idioma_id":5,"titulo":"Las envolventes constructivas en la construcción no convencional de edificios del nordeste argentino y el problema de los puentes térmicos","resumen":"SObre el problema tecnologógico que presentan las envolventes constructivas de los edificios en relación a sus comportamientos energéticos. Publicados en: https:\/\/doi.org\/10.22320\/07190700.2017.07.01.03 http:\/\/revistas.ubiobio.cl\/index.php\/RHS\/issue\/view\/253 http:\/\/revistas.ubiobio.cl\/index.php\/RHS\/article\/view\/2619","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238254,"idioma_id":5,"titulo":"Programas de mejora genética de rumiantes menores basados en comunidades","resumen":"Una revisión reciente del estado del conocimiento, principios y ejemplos de programas de mejoramiento, descriptos como basados en comunidades (PMBC), indica que por lo general se refieren a sistemas de bajos insumos con productores que tienen un interés común para mejorar y compartir sus recursos genéticos. PMBC son más frecuentes con productores de rumiantes menores, en particular pequeñosproductores de razas locales, que con bovinos, porcinos o aves de corral, para los cuales los productores suelen tener un acceso más fácil a material genético o programas alternativos. Restricciones que limitan la adopción de las tecnologías convencionales de mejoramiento genético en sistemas de bajos insumos cubren una gama de aspectos organizativos y técnicos. El análisis de siete PMBC ubicados en países de América Latina, África y Asia pone de relieve la importancia que tiene la participación de los productores e instituciones locales en las etapas de planificación e implementación desde su inicio. El análisis también revela una alta dependencia de estos programas de apoyo organizativo, técnico y financiero. Evaluaciones socioeconómicas formales de PMBC proporcionan a los gobiernos y otros organismos de desarrollo la información necesaria para aumentar la escala y extender las experiencias de programas exitosos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238255,"idioma_id":4,"titulo":"2-Arachidonoylglycerol metabolism is differently modulated by oligomeric and fibrillar conformations of amyloid beta in synaptic terminals","resumen":"Alzheimer?s disease (AD) is the most prevalent disorder of senile dementia mainly characterized by amyloid-beta peptide (Ab) deposits in the brain. Cannabinoids are relevant to AD as they exert several beneficial effects in many models of this disease. Still, whether the endocannabinoid system is either up- or down-regulated in AD has not yet been fully elucidated. Thus, the aim of the present paper was to analyze endocannabinoid 2-arachidonoylglycerol (2-AG) metabolism in cerebral cortex synaptosomes incubated with Ab oligomers or fibrils. These Ab conformations were obtained by aging the 1-40 fragment of the peptide under different agitation and time conditions. A diminished availability of 2-AG resulting from a significant decrease in diacylglycerol lipase (DAGL) activity was observed in the presence of large Ab1-40 oligomers along with synaptosomal membrane damage, as judged by transmission electron microscopy and LDH release. Conversely, a high availability of 2-AG resulting from an increase in DAGL and lysophosphatidic acid phosphohydrolase activities occurred in the presence of Ab1-40 fibrils although synaptosomal membrane disruption was also observed. Interestingly, neither synaptosomal mitochondrial viability assayed by MTT reduction nor membrane lipid peroxidation assayed by TBARS formation measurements were altered by Ab1-40 oligomers or fibrils. These results show a differential effect of Ab1-40 peptide on 2-AGmetabolism depending on its conformation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238256,"idioma_id":5,"titulo":"Efecto de tratamientos silvícolas en variables dasométricas de Pinus elliottii var. elliottii × Pinus caribaea var. Hondurensis","resumen":"Sin resumen (en prensa)","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238257,"idioma_id":5,"titulo":"¿Cómo generar un modelo tridimensional in vitro a partir de un adenocarcinoma mamario murino?","resumen":"Las mamosferas son un modelo esferoide tumoral multicelular. Estas son utilizadas como un sistema de cultivo que se asemeja a la tridimensionalidad de los tumores. En este trabajo, hemos desarrollado este modelo utilizando un adenocarcinoma mamario murino con el fin de poder estudiar la fisiología tumoral y posibles aplicaciones terapéuticas. Se han probado diversas técnicas descriptas en trabajos previos. La mejor condición fue usar placas multiwells-96 en forma de V con la adición de una monocapa de agarosa, ya que se generaron esferas compactas y robustas. Además, hemos realizado tinciones histológicas de las mamosferas con hematoxilina-eosina para la observación de su estructura mediante microscopia óptica, y técnicas de inmunohistoquímica para evaluar el índice de proliferación celular y de neovascularización, con bromodeoxiuridina y VEGF (factor de crecimiento de endotelio vascular), respectivamente. Además, hemos estudiado la formación de estas mamosferas utilizando células tumorales y células madre mesenquimales derivadas de cordones umbilicales humanos para evaluar su interacción.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238259,"idioma_id":4,"titulo":"Latex peptidases of Calotropis procera for dehairing of leather as an alternative to environmentally toxic sodium sulfide treatment","resumen":"Dehairing of crude leather is a critical stage performed at the beginning of its processing to obtain industrially useful pieces. Tanneries traditionally apply a chemical process based on sodium sulfide. Since this chemical reactive is environmentally toxic and inefficiently recycled, innovative protocols for reducing or eliminating its use in leather depilation are welcomed. Therefore, latex peptidases fromCalotropis procera (CpLP) and Cryptostegia grandiflora (CgLP) were assayed for this purpose. Enzyme activity on substrates representative of skin such as hide powder azure (UHPA), elastin (UE), azocollagen (UAZOCOL), keratin (UK), and epidermis (UEP) was determined, while depilation activity was assayed on cow hide. Only CpLP was activeagainst keratin (13.4 UK) and only CgLP was active against elastin (0.12 UE). CpLP (93.0 UHPA, 403.6 UAZOCOL, 36.3 UEP) showed higher activity against the other substrates than CgLP (47.6 UHPA, 261.5 UAZOCOL, 8.5 UEP). In pilot assays, CpLP (0.05% w\/v with sodium sulfite 0.6% w\/v as activator) released hairs from cow hide pieces. Macroscopic and microscopic analyses of the hide revealed that the dehairing process was complete and the leather structure was preserved. The proteolytic system of C. procera is a suitable bioresources to be exploited by tanneries.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238260,"idioma_id":4,"titulo":"Qualitative and quantitative factors affecting the relationship between Canola leaf spot epidemic and stem base canker (Leptosphaeria maculans) in Argentina","resumen":"Stem base canker caused by Leptosphaeria maculans (SBC) has been reported to affect canola production worldwide. Ascospores infections produce leaf spots (LS) in early vegetative stages. From these initial spots, the fungus grows towards the stem crown and may cause SBC, lodging and premature ripening at maturity. Growth stage at LS presence, cultivar resistance and environment conditions are factors associated with SBC severity. Since there are no studies that associate the LS epidemic with SBC for the Argentine cropping conditions we performed two experiments to address this essential knowledge for SBC management. In 2010, plants of four cultivars (varying in their level of resistance to LS and SBC) ranging from cotyledon stage up to 9 developed leaves were transplanted to a field where artificial inoculation was carried out by spreading infected canola stubble from the previous year. The probability of SBC occurrence depended on the interaction between cultivar resistance level and the number of developed leaves at the moment of LS detection. Based on these results, in 2011 plots of the most susceptible cultivar (Nexera 8450) received different fungicide protection treatments (azoxystrobin or propiconazole and timing of spraying) and were exposed to natural L. maculans infections. We observed that the maximum incidence of LS up to 8th developed leaf best correlated with SBC severity at maturity and a linear regression was fitted to model the relationship between these two variables.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238262,"idioma_id":4,"titulo":"Anthocyanins inhibit tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity","resumen":"An increased permeability of the intestinal barrier is proposed as a major event in the pathophysiology of diseases\/conditions characterized by chronic gut inflammation.  This study investigated the capacity of various plants extracts, containing different types and amounts of anthocyanins (AC), to inhibit tumor necrosis alpha (TNF&#945;)-induced permeabilization of Caco-2 cell monolayers, characterizing the relative protective capacity of individual AC.  Caco-2 cells differentiated into intestinal epithelial cell monolayers were incubated in the absence\/presence of (TNF&#945;,) with or without the addition of AC-rich extracts (ARE) or pure AC.  ARE inhibited TNF&#945;-induced loss of monolayer permeability assessed as changes in transepithelial electrical resistance (TEER) and paracellular transport of FITC-dextran. Within the range of concentrations studied, the protective actions of the extracts on TNF&#945;-induced TEER increase was positively correlated with cyanidins (r2=0.73) and delphinidins (r2=0.81) extract content. However no correlation was observed between TEER and ARE total AC, malvidin, petunidin, or peonidin content. Similarly, when the action of pure AC (0.1-1 &#956;M) was assessed, cyanidin, delphinidin, but not malvidin protected the monolayer from TNF&#945;-induced decrease of TEER and increased FITC-dextran permeability. These results suggest that foods or supplements containing cyanidins and delphinidins could mitigate the adverse dietary and lifestyle causes of inflammatory conditions affecting the gastrointestinal tract","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238263,"idioma_id":4,"titulo":"Development of a Simple and Economical Diagnostic Test for Canine Leishmaniasis","resumen":"Visceral leishmaniasis is a public health problem worldwide. The early diagnosis in dogs is crucial, since they are an epidemiologically relevant reservoir of the disease. The aim of a field study is to early identify the disease allowing rapid intervention to reduce its effects. We propose an immunoagglutination test as a visual in situ method for diagnosis of canine visceral leishmaniasis. Latex-protein complexes were sensitized by covalent coupling of a chimeric recombinant antigen of Leishmania spp. onto polystyrene latex with carboxyl functionality. The reaction time and the antigen concentration under which the immunoagglutination assay shows greater discrimination between the responses of a positive control serum and a negative control serum were determined. Then, the latex-protein complexes were evaluated as a visual diagnostic tool with a panel of 170 sera. The test may be read between 2-5 min and can be performed even using sera with elevated concentration of lipids, bilirubin or with variable percentage of hemolysis. The sensitivity, the specificity and the diagnostic accuracy were 78%; 100% and >80%, respectively. The visual immunoagglutination test is of potential application as a method for field studies because it shows results in less than 5 min, it is easy to implement and does not require sophisticated equipment","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238265,"idioma_id":4,"titulo":"Petrogenesis of volcanic rocks that host the world-class Ag Pb Navidad District, North Patagonian Massif: Comparison with the Jurassic Chon Aike Volcanic Province of Patagonia, Argentina","resumen":"We present the first study of the volcanic rocks of the Cañadón Asfalto Formation that host the Navidad worldclass Ag + Pb epithermal district located in the North Patagonian Massif, Patagonia, Argentina. These volcanic and sedimentary rocks were deposited in a lacustrine environment during an extensional tectonic regime associated with the breakup of Gondwana and represent themafic to intermediate counterparts of the mainly silicicJurassic Chon Aike Volcanic Province. Lava flows surrounded by autobrecciated carapace were extruded in subaerial conditions, whereas hyaloclastite and peperite facies suggest contemporaneous subaqueous volcanism and sedimentation. LA-ICPMS U\\\\Pb ages of zircon crystals from the volcanic units yielded Middle Jurassic ages of 173.9±1.9Ma and 170.8±3 Ma. In theNavidad district, volcanic rocks of the Cañadón Asfalto Formation show arc-like signatures including high-K basaltic-andesite to high-K dacite compositions, Rb, Ba and Th enrichmentrelative to the less mobile HFS elements (Nb, Ta), enrichment in light rare earth elements (LREE), Y\\\\Ti depletion, and high Zr contents. These characteristics could be explained by assimilation of crustal rocks in theJurassic magmas, which is also supported by the presence of zircon xenocrysts with Permian and Middle- Upper Triassic ages (281.3 Ma, 246.5, 218.1, and 201.3 Ma) and quartz xenocrysts recognized in these volcanic units. Furthermore, Sr and Nd isotope compositions suggest a contribution of crustal components in theseMiddle Jurassic magmas. High-K basaltic andesite has initial 87Sr\/86Sr ratios of 0.70416?0.70658 and &#958;Nd(t) values of -5.3 and -4. High-K dacite and andesite have initial 87Sr\/86Sr compositions of 0.70584? 0.70601 and &#958;Nd(t) values of -4,1 and -3,2. The range of Pb isotope values (206Pb\/204Pb = 18.28?18.37, 207Pb\/204Pb = 15.61?15.62, and 208Pb\/204Pb = 38.26?38.43) of Navidad volcanic rocks and ore minerals suggest mixing Pb sources with contributions ofmantle and crust. 206Pb\/204Pb isotopic ratios of Jurassic volcanicrocks of the Chon Aike Volcanic Province and sulfides of associated epithermal deposits increase with time from the volcanic event V1 (188?178 Ma) to volcanic events V2 (172?162 Ma) and V3 (157?153 Ma), reflecting variationsin the radiogenic Pb source as volcanism was migrating towards the Proto Pacific margin of Gondwana.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238266,"idioma_id":4,"titulo":"Interpretable interval type-2 fuzzy predicates for data clustering: a new automatic generation method based on self-organizing maps","resumen":"In previous works, we proposed two methods for data clustering based on automatically discovered fuzzy predicates which were referred to as SOM-based Fuzzy Predicate Clustering (SFPC) [Meschino et al., Neurocomputing, 147, 47?59 (2015)] and Type-2 Data-based Fuzzy Predicate Clustering (T2-DFPC) [Comas et al., Expert Syst. Appl., 68, 136?150 (2017)]. In such methods, fuzzy predicates allow both data clustering and knowledge discovering about the obtained clusters. This last feature constitutes novelty comparing to other existing approaches and it is a major contribution in the data clustering field. Based on these previous methods, in the present paper a new automatic clustering method based on fuzzy predicates is proposed which uses Self-Organizing Maps (SOMs) and is called Type-2 SOM-based Fuzzy Predicate Clustering (T2-SFPC). The new method does not require any prior knowledge about the clustering addressed. First, a random partition is defined on the dataset to be clustered and SOMs are configured and trained using the resulting data subsets. Second, an automatic clustering approach is applied on the SOM codebooks, discovering representative data of the different clusters, which are called cluster prototypes. Third, interval type-2 membership function formed by Gaussian-shape sub-functions and fuzzy predicates are defined, allowing data clustering and its interpretation. The proposed method preserves all the advantages of the previous methods SFPC and T2-DFPC in relation to the knowledge extraction capabilities and their potential application on distributed clustering and parallel computing, but results obtained on several public datasets tested showed more compactness and separation of the clusters defined by the T2-SFPC, outperforming both the previous methods and the several classical clustering approaches tested, considering internal and external validation indices. Additionally, both clustering interpretation and optimization capabilities are improved by the proposed method when compared to the methods SFPC and T2-DFPC.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238267,"idioma_id":4,"titulo":"Discovering knowledge from data clustering using automatically-defined interval type-2 fuzzy predicates","resumen":"In data clustering fuzzy predicates act as cluster descriptors providing linguistically expressed knowledge which indicates how features are related to each cluster. Fuzzy predicates directly and automatically obtained from data enable discovering knowledge inside clusters, even when there is no prior-information about the clustering problem. In this work a new method for automatic discovering of interval type-2 fuzzy predicates in data clustering is proposed, called Type-2 Data-based Fuzzy Predicate Clustering (T2-DFPC). In a first stage, a data analysis is performed by making a random partition of the original data and running a clustering scheme that automatically determines the suitable number of clusters. From this stage, interval type-2 fuzzy predicates are discovered. Results obtained on very different clustering datasets show that the T2-DFPC method was consistently one of the best in terms of accuracy. The method preserves all known advantages of the interval type-2 FL to deal with problems with vagueness, quantifying the degree of truth of the fuzzy predicates and modelling the variability of the data inside the clusters. The proposed method is a fast, useful, general, and unsupervised approach for interpretable data clustering, being the knowledge-extracting capabilities one of the main contributions. Linguistic expressions can be easily adapted to match the terminology used in the field the data are related to. The predicates are able to generalize the knowledge for new cases (new data), as an intelligent system. This new approach might be surprisingly useful in contexts where, besides the clustering partition, summary information from data is of interest.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238273,"idioma_id":4,"titulo":"Increased prevalence of human herpesvirus type 8 (HHV-8) genome among blood donors from North-Western Argentina.","resumen":"The prevalence of HHV-8 infection varies widely in South American populations, displaying geographical variations in its distribution. The heterogeneous genetic contributions provided by the transatlantic parental populations that modified the Native American genomes may explain this epidemiological observation. Aiming to determine the prevalence of HHV-8 genome among healthy South American blood donors and its potential association with genetic ancestry, 772 individuals were screened by a highly sensitive PCR protocol and ancestry was assessed in 414 samples. HHV-8 DNA was significantly more prevalent among North-western Argentines than among those from the metropolitan region (P&#8201;=&#8201;0.001) and Bolivians (P&#8201;=&#8201;0.0008), but no differences were found when compared with Peruvians and Paraguayans. Although significant differences were observed in the ancestry components of the studied populations, no association was found in the genetic admixture between HHV-8 [+] and HHV-8 [-] samples from the same place. These results support the hypothesis of the existence of geographical factors related to HHV-8 prevalence which could be explained by the presence of specific risk factors, cultural characteristics or behaviors, probably related to contaminated saliva and\/or sexual transmission. The presence of HHV-8 in South American blood units available for transfusion and an increased risk of infection in some provinces of North-western Argentina represent a hazard for immunosuppressed recipients.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238274,"idioma_id":4,"titulo":"Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals","resumen":"In recent years, great progress has been made in the field of new therapeutic options for hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a great hope for millions of chronically infected individuals because their use may lead to excellent cure rates with fewer side effects. In Latin America, the high prevalence of HCV genotype 1 infection and the significant association of Native American ancestry with risk predictive single-nucleotide polymorphisms (SNPs) in IFNL4 and ITPA genes highlight the need to implement new treatment regimens in these populations. However, the universal accessibility to DAAs is still not a reality in the region as their high cost is one of the major, although not the only, limiting factors for their broad implementation. Therefore, under these circumstances, could the assessment of host genetic markers be a useful tool to prioritize DAA treatment until global access to these new drugs can be achieved? This review will summarize the scientific evidences and the potential implications of HCV pharmacogenomics in this rapidly evolving era of anti-HCV drug development.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238275,"idioma_id":4,"titulo":"Macro- and microclimate conditions lead to rapid grapevine deacclimation: Evidences of thermal amplitude incidence from two contrasting wine regions from North and South America","resumen":"Low temperature is a limiting factor that affects vineyard distribution globally. The level of cold hardiness acquired during the dormant season by Vitis sp. is crucial for winter survival. Most research published on this topic has been generated beyond 40° N latitude, where daily mean temperatures may attain injurious levels during the dormant season resulting in significant damage to vines and buds. Symptoms of cold injury have been identified in Mendoza (32?35° S latitude), a Southern Hemisphere wine region characterized by a high thermal amplitude, and warm winds during the dormant season. These symptoms have usually been attributed to drought and\/or pathogens, but not to rapid deacclimation followed by injurious low temperatures. Because local information on meteorological events as probable causes is scarce, this research was designed to test and study this assumption by comparing macro-, meso-, and microclimatic data from Mendoza, Argentina, and eastern Washington, USA. The goal was to unveil why freezing damage has occurred in both regions, despite the existence of large climatic differences. Because environmental parameters under field conditions may not correspond to data recorded by conventional weather stations, sensors were installed in vineyards for comparison. Microclimatic conditions on grapevines were also evaluated to assess the most vulnerable portions of field-grown grapevines. In order to better understand if it may be possible to modify cold hardiness status in a short period with high thermal amplitude conditions, deacclimation was induced using a thermal treatment. Hence, despite the fact that Mendoza is warmer, and temperatures are not as extreme as in Washington, high daily thermal amplitude might be partially involved in plant deacclimation, leading to a differential cold hardiness response.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238281,"idioma_id":5,"titulo":"Morfología polínica de las especies de Ludwigia (Onagraceae, Ludwigioideae) del Noroeste de Argentina","resumen":"Se describe la morfología polínica de siete taxonesdel género Ludwigia (Onagraceae, Ludwigioideae) presentes en el noroeste de Argentina: L. bonariensis, L. decurrens, L. grandiflora ssp. hexapetala, L. major, L. octovalvis, L. peploides ssp. peploides y L. peruviana. Las observaciones y mediciones de granos de polen acetolizadosy sin acetolizar se realizaron con microscopio óptico (MO) mientras que para los estudios con microscopio electrónico de barrido (MEB) se trabajó con granos no acetolizados. Los granos son suboblatos a oblatos, tricolporados y de simetría subisopolar, con poros prominentes,aspidados y se presentan en mónades (33-84 &#956;m) o reunidos en tétrades (52-102 &#956;m). Los hilos de viscina, característicos de la familia, se insertan principalmente en el polo proximal. Los colpos son estrechos y cor tos o largos. La escultura de la exina varía de rugulada arugulada ? estriada fina. En algunos taxones se observan crestas meridionales y laterales. Se analizan diferencias palinológicas entre las entidades estudiadas y se ofrece una clave para su identificación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238283,"idioma_id":4,"titulo":"Chemical derivatization of natural extracts obtained from Larrea divaricata Cav. increase in the antioxidant activity and protein precipitating capacity","resumen":"In the present work modified extracts of Larrea divaricata was obtained by chemical transformations in order to improve the antioxidant activity and the protein precipitating capacity.  Apigenine-7-methylether, quercetin, nor dihydroguaiaretic acid, 3,4-dihydroxy-3,4-dimethoxy-6,7-cyclolignan and pcoumaric acid were identified in the methanolic extract by Electron Impact Mass Spectrometry (EIMS). Chemically modified extracts were prepared through acid hydrolysis, sulfonylation, O-methylation, O-acylationand C-acylation reactions. Total phenolics and flavonoids contents were determined by spectrophotometric methods.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238284,"idioma_id":4,"titulo":"?Anti-inflammatory Activity and Antioxidant Potential of Aqueous Extracts from Stem Bark of Geoffroea Decorticans?","resumen":"In the present work we investigated, for the first time, the anti-inflammatory activity and the antioxidant properties of aqueous and ethanolic extracts, obtained from stem bark of Geoffroea decorticans (Gill. ex Hook. et Arn.) Burk. (Fabaceae). G. decorticans, commonly known as ?chañar? or ?chañarcillo?, is a traditional argentinean plant used as emollient, balsamic, antitussive, expectorant and anti-inflammatory. The stem bark was collected from San Francisco del Monte de Oro, San Luis, Argentina. Anti-inflammatory activity was evaluated by carrageenan-induced paw edema in rats. Antioxidant activity was tested using 1,1-Diphenyl-2-picrylhydrazyl radical-scavenging activity (DPPH), 2,2´-Azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) radical scavenging activity (ABTS) and ferric ion-reducing power (RP-Fe) assays. Aqueous extract 10% p\/v showed anti-inflammatory  activity (3h, 48% inhibition, 5h 37% inhibition and 7h 17% inhibition) and antioxidant activity (DPPH, IC50 (mg\/mL) =0.098 ± 0.032; ABTS, IC50 (mg\/mL) =0.022 ± 0.343, RP-Fe IC50 (mg\/mL) =1.124 ± 0.146). In the other hand, the ethanolic extract 5%p\/v, presented anti-inflammatory activity (3h, 34% inhibition, 5h 38% inhibition and 7h 35% inhibition) and antioxidant activity (DPPH, IC50 (mg\/mL) =0.133 ± 0.027; ABTS, IC50 (mg\/mL) =0.086 ± 0.262, RP-Fe IC50 (mg\/mL) =7.089 ± 0.104). These results suggest that, also fruits, the aqueous and ethanolic extracts from the stem bark of G. decorticans present significant anti-inflammatory activity and antioxidant properties.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238285,"idioma_id":4,"titulo":"Unexpected effect of citrate ions on the corrosion process of carbon steel in alkaline solutions","resumen":"The effect of citrate ions on the passive film stability on carbon steel, at pH 13, was evaluated. The study involved cyclic voltammograms, potentiodynamic polarization curves, micro-Raman spectroscopy and weight-loss tests. No beneficial effects on delaying or inhibiting pitting were observed in the presence of citrate ions. Organic compounds with carboxylate groups are promising corrosion inhibitors. However, the incorporation of citrate ions is clearly harmful to carbon steel in alkaline solutions and accelerates the corrosion process. Citrate ions adsorption is not observed on passive steel. Instead, citrate ions can unexpectedly dissolve the passive layer facilitating the corrosion process.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238287,"idioma_id":5,"titulo":"Respuesta de la comunidad de fitoplancton y zooplancton al afloramiento de agua subterránea y surgencia costera en la península de Yucatán, México","resumen":"Las descargas de agua subterránea (DAS) y la surgencia costera son fenómenos oceanográficosque generan nuevas condiciones hidroquímicas en áreas costeras. El cambio en la composición y la estructurade la comunidad planctónica ante estas condiciones determina la dinámica de los niveles tróficos bajos enlos ecosistemas marino-costeros. El presente estudio describe la respuesta de la comunidad de fitoplanctony zooplancton al marco hidroquímico en dos ecosistemas costeros influenciados por dichos fenómenos en lapenínsula de Yucatán, una región tropical. Se realizaron tres campañas durante el año 2012 (junio, agosto ynoviembre) y se muestrearon transectas de 10 km de extensión. Se midieron in situ temperatura, salinidad yoxígeno disuelto. Además, se colectaron muestras de agua para la determinación de nutrientes inorgánicosdisueltos (NO2, NO3, NH4, PO4 y SiO4) y clorofila a, y análisis de componentes de la comunidad de fitoplanctony zooplancton. En el sitio de estudio influenciado por las DAS (Dzilam de Bravo, 21°23?33?? N - 88°53?29?? O),incrementos en la densidad de copépodos (2484±890 org\/L), sincronizados con disminuciones en la densidadde diatomeas centrales, pennadas y dinoflagelados (1600±1704, 8730±8951 y 22010±3557 cél\/L, respectivamente)en noviembre dan indicios de un cierto control de la comunidad de fitoplancton por parte de dicho grupozooplanctónico durante momentos de mayor intensidad del fenómeno. Por otro lado, la surgencia costerade Cabo Catoche (21°36?21?? N - 87°06?12?? O) ocasionó un incremento en la densidad de diatomeas centrales(248000±126417 cél\/L), lo que resultó en una dominancia clara de este grupo durante el período de intensificacióndel fenómeno, mientras que los dinoflagelados dominaron en momentos de relajación de la surgencia. Las DASen Dzilam de Bravo y la surgencia costera en Cabo Catoche generan respuestas diferenciales en la comunidadde plancton costero, e influyen en la estructura de esa comunidad y en la relación entre sus componentes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238289,"idioma_id":4,"titulo":"Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments","resumen":"In order to evaluate the potential risk of Haemonchus contortus resistant to benzimidazole (BZ) treatments to pass from sheep to cattle aseries of experiments were carried out. Two field isolates of H. contortus resistant (Ayacucho) or susceptible (Cedive) to BZ treatments werereproduced in lambs and involved in the study. Two groups of 4 calves each and two groups of 4 lambs each were infected with larvae(L3) of each isolate respectively. The number of eggs in faeces (EPG), worm count and ratio of worm establishment (RWE) were determined.The number of red blood cells, packed cell volume and haemoglobin concentration was assessed. The EPG levels were higher for Ayacuchoisolate which reached to a peak of 7,168 and 780 at day 42 post inoculation (PI) in lambs and calves respectively. The RWE at day 45 PIwas 28.8 % and 7.16% for Ayacucho isolate in lambs and calves respectively while for Cedive isolate was 36.6% and 0.04% respectively.At day 90 PI the RWE was of 1.94% and 0.69% in lambs for Ayacucho and Cedive isolate respectively, whereas no worms were recoveredfrom calves. The haematological parameters in lambs and calves did not show significant differences between isolates. The present studiesdemonstrate that some populations of H. contortus may complete life cycle in calves and remain established for at least a 45 days periodPI. This finding should be strongly considered when farm production involves mixed or alternate sheep\/cattle grazing and backgrounds ofanthelmintic resistance.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238290,"idioma_id":4,"titulo":"Symmetry energy in the liquid-gas mixture","resumen":"Results from classical molecular dynamics simulations of infinite nuclear systems with varying density, temperature and isospin content are used to calculate the symmetry energy at low densities. The results show an excellent agreement with the experimental data and corroborate the claim that the formation of clusters has a strong influence on the symmetry energy in the liquid?gas coexistence region.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238291,"idioma_id":4,"titulo":"The food web of Potter Cove (Antarctica): complexity, structure and function","resumen":"The study of food web structure and complexity are central to better understand ecosystem functioning. A food-web approach includes both species and energy flows among them, providing a natural framework for characterizing species? ecological roles and the mechanisms through which biodiversity influences ecosystem dynamics. Here we present for the first time a high-resolution food web for the Potter Cove marine ecosystem (Antarctica). We studied eleven food web properties to analyze network complexity, structure and topology. We found a low linkage density (3.4), connectance (0.04) and omnivory percentage (45), as well as short path length (1.8) and low clustering coefficient (0.08). Furthermore, relating the structure of the web to its dynamics, we found an exponential degree distribution (in- and out-links) suggesting that Potter Cove food web may be fragile if the most connected species got extinct. For two of the three more connected functional groups, competition overlap graphs reflect high trophic interaction between demersal fish and niche specialization according to feeding strategies in amphipods. On the other hand, it can be inferred from the prey overlap graph that multiple energy pathways of carbon flux exist across benthic and pelagic habitats in Potter Cove ecosystem. Although alternative food sources might add robustness to the web, network properties (low linkage density, connectance and omnivory) suggest fragility and potential trophic cascade effects.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238293,"idioma_id":4,"titulo":"Phenolic compounds profiling of virgin olive oils from different varieties cultivated in Mendoza, Argentina, by using liquid chromatography-mass spectrometry","resumen":"The aim of this work was to achieve a preliminary characterization of the profile of the phenolic fraction of virgin olive oils (VOOs) from Maipú (Mendoza, Argentina). Thus, 25 commercial VOO samples from Arauco, Arbequina, Picual, Frantoio, Changlot, Empeltre, Nevadillo, Manzanilla and Coratina (both monovarietals and blends) were analyzed using LC-ESI-QTOF MS and LC-ESI-IT MS for identification and quantification purposes, respectively. A rapid LC method (15 min) accomplished quantitative information about a total of 40 phenolic compounds, including secoiridoid derivatives, which have not been evaluated before in samples coming from the sub-region so-called Maipú (Mendoza province, Argentina). The results make evident that olive oils coming from Mendoza can be considered as important sources of phenolic bioactive compounds, exhibiting similar phenolic compounds levels to those shown by oils from other typical world production regions. Moreover, some distinctive features of Arauco variety (Argentinean autochthonous variety) were pointed out; indeed, a correlation between flavonoids content and botanical variety was established herewith.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238294,"idioma_id":5,"titulo":"Productos culturales conmemorativos. La azarosa constitución de la Casa Histórica de la Independencia durante la década de 1940","resumen":"Las representaciones del pasado y las modulaciones de la memoria colectiva resultan de procesos socio-culturales complejos y de largo plazo que involucran de manera indefectible la esfera política. Partiendo de esta premisa, el artículo explora algunas prácticas vinculadas a la fabricación de bienes y productos culturales utilizados en dispositivos conmemorativos. Concretamente, se reconstruyen los proyectos diseñados en torno al Salón de la Jura y la Casa Histórica de la Independencia en Tucumán, durante la década de 1940, cuando el inmueble pasó a ser administrado por la Comisión Nacional de Museos, Monumentos y Lugares Históricos y fue reconstruido en base a las características edilicias que había tenido en 1816: se analizan los actores e instituciones que intervinieron, los avatares del proceso de acuerdo a los vaivenes políticos, las discusiones acerca de la reconstrucción del inmueble y las decisiones adoptadas en relación a qué exhibir y cómo dotarlo de colecciones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238295,"idioma_id":5,"titulo":"Incidencia de la fertilización foliar con potasio, calcio y boro sobre la nutrición y calidad de frutos en mandarino `Nova´ con síntomas de splitting?.","resumen":"--------","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238296,"idioma_id":4,"titulo":"Validation of kinetic modeling of progesterone release from polymeric membranes","resumen":"Mathematical modeling in drug release systems is fundamental in development and optimization of these systems, since it allows to predict drug release rates and to elucidate the physical transport mechanisms involved. In this paper we validate a novel mathematical model that describes progesterone (Prg) controlled release from poly-3-hydroxybutyric acid (PHB) membranes. A statistical analysis was conducted to compare the fitting of our model with six different models and the Akaike information criterion (AIC) was used to find the equation with best-fit. A simple relation between mass and drug released rate was found, which allows predicting the effect of Prg loads on the release behavior. Our proposed model was the one with minimum AIC value, and therefore it was the one that statistically fitted better the experimental data obtained for all the Prg loads tested. Furthermore, the initial release rate was calculated and therefore, the interface mass transfer coefficient estimated and the equilibrium distribution constant of Prg between the PHB and the release medium was also determined. The results lead us to conclude that our proposed model is the one which best fits the experimental data and can be successfully used to describe Prg drug release in PHB membranes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238297,"idioma_id":5,"titulo":"El presente de la comunicación científica. The present of scientific communication","resumen":"La humanidad es testigo de un cambio vertiginoso en los modos y formas de comunicación e información; desde la irrupción de las TIC, todo acto comunicacional ha sido objeto de modificación. Las nuevas formas de acceso a la información científica cosechan cada vez más adeptos y gozan del reconocimiento de miles de intelectuales que se han expresado sobre este fenómeno reconociéndolo como ?el nuevo paradigma de la comunicación científica?. Esto nos enfrenta a un modelo moderno, ágil en su concepción colaborativa y dinámico en su difusión y socialización. Los países en vías de desarrollo necesitan accederal conocimiento actualizado resultante de las investigaciones como insumo básico para la comprensión, el análisis, la confrontación de la realidad en las distintas áreas del saber y para la generación, la creación de nuevos saberes aplicables a la resolución de problemas. Aquí se presenta un estado de situación.Abstract:Humanity is witness to a vertiginous change in the modes and forms of communication and information; with the emergence of ICT, every communicational act has been modified. The new forms of access to scientific information are attracting more and more enthusiasts and enjoy the recognition of thousands of intellectuals, who have expressed about this phenomenon recognizing it as ?the new paradigm of scientific communication?; This confronts us with a modern model, agile in its collaborative conception and dynamic in its diffusion and socialization. Developing countries need access to up-to- date knowledge resulting from research, as a basic input for understanding,analyzing, confronting reality with the various areas of knowledge and for the generation, and the creation of new knowledge in problem solving. Here is a statement on the situation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238298,"idioma_id":4,"titulo":"Risk factors associated with tuberculosis mortality in adults in six provinces of Argentina","resumen":"Tuberculosis (TB) remains a cause of illness and death across the world, especially in developingcountries and vulnerable population groups. In 2013, 1.5 million died from the disease worldwide. In Argentina, the largest proportion of TB-related deaths occurred in the northern provinces. Several international studies reported that TB mortality was related to the presence of certain comorbidities and socio-demographic characteristics. Our aim was to investigate the main risk factors associated with TB mortality in adults from six provinces in Argentina, especially those with higher TB mortality rates. A retrospective case-control study was conducted. It included all patients of &#8805;18 years with clinical and\/or bacteriological TB diagnosis who underwent treatment from January 1st, 2012 to June 30th, 2013. Socio-demographic, clinical and bacteriological variables were surveyed. Information on 157 cases and 281 controls was obtained. Patients reported as deceased to the TB Control Program were considered cases, and those whose treatment result was reported as successful in the same time period were considered controls. For 111 deaths, the average time elapsed between the start of treatment and death was 2.3 months; median: 1. TB-related mortality was associated with poor TB treatment adherence (OR: 3.7 [1.9-7.3], p: 0.000), AIDS (OR: 5.29 [2.6-10.7], p: 0.000), male gender (OR: 1.7 [1.1-2.5], p: 0.009), belonging to indigenous people (OR: 7.2 [2.8-18.9], p:0. 000) and age &#8805; 50 (OR: 2.2 [1.4-3.3], p: 0.000). By multivariate analysis the two first associations were confirmed. This study sets up the basis for planning inter-program and inter-sector work to accelerate the decline in the inequitable TB mortality.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238300,"idioma_id":5,"titulo":"Diagnostico de Osteoatrosisde Articulaciòn Temporomandibular con Tomografìa de Haz Cònico","resumen":"La osteoartrosis es una patología de carácter degenerativo que afecta a la articulación temporomandibular. Si bien el examen clínico representa una herramienta fundamental para su diagnóstico, los estudios imagenológicos son los que permitirán la confirmación de dicho diagnóstico. En la actualidad la tomografía computada de haz cónico resulta el método de elección debido a que nos permite ver con detalle las estructuras óseas de la articulación temporomandibular en diferentes planos utilizando una dosis baja de radiación en comparación con la tomografía computada médica.*","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238303,"idioma_id":5,"titulo":"Evaluación de la Avifauna Para Uso Ecoturístico en Humedales del Sur de Santa Cruz","resumen":"Este estudio comprende una valoración cuali-cuantitativa de las especies de aves asociadas ecológicamente a humedales del sur de la provincia de Santa Cruz, Argentina. Se trabajó en dos reservas naturales municipales con una rica diversidad de aves, la Reserva Costera Urbana en Río Gallegos y Reserva Natural Municipal Laguna Nimez en El Calafate. Se seleccionaron un total de 27 especies de aves posibles de observar entre ambas reservas por su potencial para ser aprovechadas para la práctica del aviturismo, ponderando de forma diferenciada entre quienes lo realizan de forma ocasional y profesional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238304,"idioma_id":4,"titulo":"A new approach to fishery waste revalorization to enhance Nile tilapia (Oreochromis niloticus) digestion process","resumen":"The main goal of this research was to analyse in vitro compatibility of Nile tilapia (Oreochromis niloticus) digestive proteinases and enzymes recovered from species comprising fishery waste as Pleoticus muelleri, Artemesia longinaris and Patagonotothen ramsayi. It evaluated the use of exogenous enzymes as feed supplements to increase digestion efficiency in tilapia fingerlings and juveniles (3.5 ± 0.11 g and 11.6 ± 1.5 g, respectively). We successfully have obtained proteinases from fishery waste as sourceof exogenous enzymes. P. muelleri and A. longinaris enzymes had more activity of acid and alkaline proteinases than P. ramsayi. SDS-PAGE gels demonstrated that Nile tilapia digestive proteinases keep their activity when combined with each exogenous proteinase.Exogenous enzymes varied in their ability to enhance hydrolysis of differentfeed ingredients. P. muelleri by-products are the best candidates to be employed as feed supplements for tilapia juveniles. Enzymes from this by-product did not affect the activity and integrity of fish digestive enzymes, improved the hydrolysis of different protein sources (fish meal, squid meal, shrimp meal and soybean meal), and maintained its activity after being exposed to high temperatures and acid pHs. Our findings are applicable to other places where O. niloticus is raised utilizing local fishery waste, and also to different cultured species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238305,"idioma_id":4,"titulo":"Exogenous enzymes in dairy technology: acidic proteases from processing discards of shrimp Pleoticus muelleri and their use as milk-clotting enzymes for cheese manufacture","resumen":"Argentina is the seventh largest world producer of cheese. Owing to the profitability of this industry,more than a thousand of dairy companies and farms exclusively produce cheeses, and, thus, this activityutilises 42% of total raw milk production of the country. Due to the increase in cheese demand, andbecause calf rennet is relatively expensive, this has motivated the study of new sources of proteases due tothe potential use in biotechnological processes. Previously, crustacean proteases have been considered asgood rennet substitutes for milk coagulation during the cheese making process. The aim of this study wasto evaluate and characterise acidic proteases obtained from Pleoticus muelleri discards and their proteolyticcapability as well as their potential use as a milk-clotting agent. The activity of aspartic proteasesand the satisfactory acceptation by the taste panel for cheese made with shrimp?s enzymes suggest thatP. muelleri proteins offer a high potential for use in dairy biotechnological processes with potential use asmilk-clotting agents for cheese making.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238309,"idioma_id":5,"titulo":"Somos familia. Ficciones sobre el origen en niños nacidos por TRHA","resumen":"El avance en las técnicas de reproducción asistida, acompañado por las novedades legislativas en derecho de familia, han posibilitado diversas conformaciones familiares. Parte de la educación en derechos humanos que propone este equipo de investigación supone formalizar la experiencia adquirida para poder transmitirla. Presentamos a continuación una breve articulación respecto del libro ?Somos familia? ganador del PDE2016 de la Facultad de Psicología, Universidad de Buenos Aires. Contar sobre los orígenes ha sido la consigna que nuclea los relatos cortos que componen el libro, como así también el eje de los talleres a la comunidad que tuvieron por objeto visibilizar la diversidad familiar.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238310,"idioma_id":5,"titulo":"Arte y Psicoanálisis: tres vías de exploración del proceso artístico","resumen":"La creación artística atestigua el paso del tiempo en el devenir de la historia cultural. El siguiente ensayo explora tres vías de acceso a las dinámicas del proceso artístico. El relato corto Las ruinas circulares (1976) del escritor argentino Jorge Luis Borges será la oportunidad para indagar la perspectiva hermenéutica sobre el simbolismo creacionista, la realidad, el simulacro y la ficción. Luego, analizaremos la perspectiva que introduce el sistema de idealismo trascendental (Schelling, 1800) que propone al arte como vía de conciliación entre consciente e inconsciente. Por último, el análisis de la obra Freud: una interpretación de la cultura (Ricoeur, 1970) será la oportunidad para analizar la tesis epistemológica que caracteriza al discurso psicoanalítico, su doble pertenencia a la dimensión del sentido (dimensión hermenéutica) y la fuerza (dimensión energética). Para concluir con la necesidad de rescatar el aporte que el elemento artístico introduce como pausa y momento de conciliación sobre los avatares del devenir cultural.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238311,"idioma_id":5,"titulo":"La Risa: un Espejo de nuestro cerebro","resumen":"La razón del porqué las risas ajenas nos inducen a la risa, es que ésta, así como muchas otras actividades, es un comportamiento esencialmente social. Desde la Neurociencia, la risa (así como el llanto) nos ayuda a comprender como se generan lazos sociales, al jugar un papel importante dentro del proceso de interacción con los demás, a partir de la imitación y empatía. Nuestro cerebro está preparado y diseñado para socializar por lo que contiene ?neuronas espejo? las cuales se activan al ver realizar una acción e imitan como un acto reflejo lo que el otro realiza. En 1992, el científico italiano Giacomo Rizzolatti y cols., estudiaban el cerebro de macacos con el fin de descubrir cómo una región en particular del cerebro organiza los comportamientos motores. Rizzolatti descubrió que esa región cerebral se activaba no sólo cuando los monos estiraban la mano para tomar un  maní, sino también cuando veían a otros monos o humanos hacer lo mismo. En este artículo se repasa la neurobiología de la risa y del humor, y se expone como este fenómeno denominado neuronas espejo, que también se produce en los humanos, juega un rol fundamental en el contagio de la risa, en la percepción del humor, en la empatía y en los procesos que involucran a la Teoría de la Mente. Palabras clave: risa, neuronas espejo, cerebro social, humor, empatía.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238312,"idioma_id":5,"titulo":"El impacto bio-político del descubrimiento de la huella genética a partir de la mini-serie televisiva Code of a Killer (2015) y su incidencia en las sociedades actuales","resumen":"La serie Code of a Killer, presenta bajo la forma de una novela policial, el avance de la ciencia en la determinación dela huella genética. Dicho descubrimiento revolucionó el campo científico permitiendo una nueva forma de identifi&#8208;cación de las personas. Sus usos se inscriben más allá de lo calculado, posibilitando una interrogación acerca delimpacto de la ciencia en la sociedad. Tomando el descubrimiento de la huella genética (también llamada prueba deADN o análisis de ADN) como técnica utilizada para distinguir a los individuos de una misma especie, pondremos endiálogo dos sucesos controvertidos y de un relevante impacto social: la revolución en la investigación forense en laprimera condena basada en el dato de la huella genética y la posibilidad de encontrar a los niños apropiados en laúltima dictadura cívico&#8208;militar argentina a partir del índice de abuelidad. En contraste con estos aspectos positivosde los desarrollos científicos sobre los derechos humanos y la investigación forense es pertinente introducir unareflexión sobre el alcance biopolítico de la huella genética en el contexto de los estados modernos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238314,"idioma_id":4,"titulo":"Interpretable interval type-2 fuzzy predicates for data clustering: a new automatic generation method based on self-organizing maps","resumen":"In previous works, we proposed two methods for data clustering based on automatically discovered fuzzy predicates which were referred to as SOM-based Fuzzy Predicate Clustering (SFPC) [Meschino et al., Neurocomputing, 147, 47-59 (2015)] and Type-2 Data-based Fuzzy Predicate Clustering (T2-DFPC) [Comas et al., Expert Syst. Appl., 68, 136-150 (2017)]. In such methods, fuzzy predicates allow both data clustering and knowledge discovering about the obtained clusters. This last feature constitutes novelty comparing to other existing approaches and it is a major contribution in the data clustering field. Based on these previous methods, in the present paper a new automatic clustering method based on fuzzy predicates is proposed which uses Self-Organizing Maps (SOMs) and is called Type-2 SOM-based Fuzzy Predicate Clustering (T2-SFPC). The new method does not require any prior knowledge about the clustering addressed. First, a random partition is defined on the dataset to be clustered and SOMs are configured and trained using the resulting data subsets. Second, an automatic clustering approach is applied on the SOM codebooks, discovering representative data of the different clusters, which are called cluster prototypes. Third, interval type-2 membership function formed by Gaussian-shape sub-functions and fuzzy predicates are defined, allowing data clustering and its interpretation. The proposed method preserves all the advantages of the previous methods SFPC and T2-DFPC in relation to the knowledge extraction capabilities and their potential application on distributed clustering and parallel computing, but results obtained on several public datasets tested showed more compactness and separation of the clusters defined by the T2-SFPC, outperforming both the previous methods and the several classical clustering approaches tested, considering internal and external validation indices. Additionally, both clustering interpretation and optimization capabilities are improved by the proposed method when compared to the methods SFPC and T2-DFPC.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238315,"idioma_id":4,"titulo":"Discovering knowledge from data clustering using automatically defined interval type-2 fuzzy predicates","resumen":"In data clustering fuzzy predicates act as cluster descriptors providing linguistically expressed knowledge which indicates how features are related to each cluster. Fuzzy predicates directly and automatically ob- tained from data enable discovering knowledge inside clusters, even when there is no prior-information about the clustering problem. In this work a new method for automatic discovering of interval type-2 fuzzy predicates in data clustering is proposed, called Type-2 Data-based Fuzzy Predicate Clustering (T2- DFPC). In a first stage, a data analysis is performed by making a random partition of the original data and running a clustering scheme that automatically determines the suitable number of clusters. From this stage, interval type-2 fuzzy predicates are discovered. Results obtained on very different cluster- ing datasets show that the T2-DFPC method was consistently one of the best in terms of accuracy. The method preserves all known advantages of the interval type-2 FL to deal with problems with vagueness, quantifying the degree of truth of the fuzzy predicates and modelling the variability of the data inside the clusters. The proposed method is a fast, useful, general, and unsupervised approach for interpretable data clustering, being the knowledge-extracting capabilities one of the main contributions. Linguistic ex- pressions can be easily adapted to match the terminology used in the field the data are related to. The predicates are able to generalize the knowledge for new cases (new data), as an intelligent system. This new approach might be surprisingly useful in contexts where, besides the clustering partition, summary information from data is of interest.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238316,"idioma_id":4,"titulo":"PhD Graduates and Students: What professional pathways exist?","resumen":"Ver adjunto","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238317,"idioma_id":4,"titulo":"Teacher training; its history, legal and political bases and educational practices today?","resumen":"Ver adjunto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238319,"idioma_id":4,"titulo":"Intergenerational Educational Mobility of PhDs and the Plafond Effects. A French-Argentine Comparative Study?","resumen":"Ver adjunto","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238320,"idioma_id":4,"titulo":"Inhibition of Helicobacter pylori and its associated urease by two regional plants of San Luis , Argentina","resumen":"The search of alternative anti-Helicobacter pylori agents obtained mainly of medicinal plants is a scientific area of great interest. The antimicrobial effects of Litrahea molleoides and Aristolochia argentina extracts against sensible and resistant H. pylori strains, were evaluated in vitro. Also, the urease inhibition activity and the effect on the ureA gene expression mRNA was evaluated. The L. molleoides and A. argentinae extracts showed antimicrobial activity against all strains assayed. Regardless of the extract assayed a decrease of viable count of approximately 2 log units on planktonic cell or established biofilms in H. pylori strains respect to the control was observed (p<0.05). Also, both extracts demonstrated strong urease inhibition activity on sensible H. pylori (p<0.05). In all strains, the ureA gene expression was down regulation independently of extracts used. The promising results of this work suggest that both L. molleoides and A. argentina, two traditional medicinal plant of Cuyo region, could be used as H. pylori alternative treatment that could attenuate virulence of bacterium and enable the host immune system to combat infection.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238322,"idioma_id":5,"titulo":"Ética e historia: una mirada desde la ética discursiva","resumen":"El siguiente trabajo se propone analizar la relación entre la ética discursiva y la historia, a partir de la reconstrucción realizada por Karl-Otto Apel en las Mercier Lectures de 1999 (Lovaina). Se intentará mostrar cómo la ética discursiva se encuentra entrelazada con las tres dimensiones del tiempo histórico. La relación con el pasado apunta al posicionamiento respecto de la situación moral e institucional 'heredada' por la tradición (eticidad sustancial). La relación con el presente se refiere a la 'situación humana', entendida esta como un proceso evolutivo-cultural (desde la hominización hasta el presente) y como un 'momento' o situación particular dentro de ese proceso. Finalmente, la relación con el futuro alude a la capacidad de la ética de orientar la historia humana hacia un horizonte normativo, en tanto ideal regulativo.Indizada en: Latindex Catálogo","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238323,"idioma_id":4,"titulo":"Epoxy-silica\/clay nanocomposite for silver-based antibacterial thin coatings: Synthesis and structural characterization","resumen":"Development of new functional coatings in the field of health care, as antibacterial applications, deals with a straight control of the diffusive properties that rules the releasing of the active component. In this work, the development of a silver-rich nanocomposite thin coating, loaded with organically modified clay nanoparticles, is presented. The synthesis process included an environment-friendly silanization process of clay nanoparticles (Laponite® S482) with (3-glycidoxypropyl)trimethoxysilane (GPTMS) and the further hydrolytic condensation with tetraethoxysilane (TEOS). Silanization process and the obtained coatings were analysed by Fourier transformed infrared spectroscopy, UV-visible spectroscopy, X-ray diffraction, thermogravimetric curves and scanning electron microscopy. The silanization process of clay nanoparticles with the organically reactive alkyl alkoxysilane, allowed to stabilize and exfoliate the clay nanosheets within a hybrid organic-inorganic sol-gel material. Ring opening of grafted epoxy groups carried to an increasing of the basal spacing, of intercalated clay nanosheets, from 1.3 to 1.8 nm. Moreover, incorporation of organically modified clay nanosheets introduced a significant stabilization on the development of silver nanoparticles inside the structure of the nanocomposite coating, retaining the silver inside the coating material and restricting the growing of silver nanoparticles on the surface of the coating. Antibacterial behaviour, against E.coli cultures, performed through agar diffusion tests, provided promisors results that allow assuming that the studied nanocomposite coating serves as a reservoir of ionic silver, allowing the antibacterial effect.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238326,"idioma_id":5,"titulo":"Hacia una nueva perspectiva de género. El caso del Poder Judicial","resumen":"-","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238328,"idioma_id":5,"titulo":"Artesano de la alegría","resumen":"Este trabajo indaga en Omar Schiliro (1962-1994), artista vinculado a la Galería de Artes Visuales del Centro Cultural Rojas de Buenos Aires fallecido a causa de sida. A través de las reflexiones que provee la teoría queer sobre la temporalidad ?con especial énfasis en los afectos?, se analizan las formas de subjetivación que hicieron a su trayectoria biográfica, los modos de resistencia a la epidemia y su apuesta estética y política por procedimientos y materiales degradados por las ficciones normativas de la cultura.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238333,"idioma_id":4,"titulo":"Thermal buffering capacity of the germination phenotype across the environmental envelope of the Cactaceae","resumen":"Recruitment from seeds is among the most vulnerable stage for plants as globaltemperatures change. While germination is the means by which the vast majority of the world?s flora regenerate naturally, a framework for accurately predicting which species are at greatest risk of germination failure during environmental perturbation is lacking. Taking a physiological approach, we assess how one family, the Cactaceae, may respond to global temperature change based on the thermal buffering capacity of the germination phenotype. We selected 55 cactus species from the Americas, all geo-referenced seed collections, reflecting the broad environmental envelope of the family across 70° of latitude and 3700 m of altitude. We then generated empirical data of the thermal germination response from which we estimated the minimum (Tb), optimum (To) and ceiling (Tc) temperature for germination and the thermal time (h50) for each species based on the linearity of germination rate with temperature. Species with the highest Tb and lowest Tc germinated fastest, and the interspecific sensitivity of the germination rate to temperature, as assessed through h50, varied tenfold. A left-skewed asymmetry in the germination rate with temperature was relatively common but the unimodal pattern typical of crop species failed for nearly half of the species due to insensitivity to temperature change at To. For32 fully characterized species, seed thermal parameters correlated strongly with the mean temperature of the wettest quarter of the seed collection sites. By projecting the mean temperature of the wettest quarter under two climate change scenarios, we predict under the least conservative scenario (+3.7°C) that 25% of cactus species will have reduced germination performance, whilst the remainder will have an efficiency gain, by the end of the 21st century","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238334,"idioma_id":4,"titulo":"Pollination biology of Echinopsis leucantha (Cactaceae): passerine birds and exotic bees as effective pollinators","resumen":"Cactus flowers have traditionally been considered to be specialized to certain pollination guilds, butpollination studies reveal that most species are actually generalists. This suggests that floral traits are not alwayspredictive of the animal visitors that pollinate cactus flowers. Here, we studied the pollination of Echinopsisleucantha (Gillies ex Salm-Dyck) Walp., an endemic cactus of Argentina, whose floral traits would suggest that it ispollinated by moths. The floral lifespan and flower availability throughout the reproductive period were evaluated.Field experiments were carried out to study the reproductive system and the identity and effectiveness offloral visitors. Echinopsis leucantha flowers had a nocturnal anthesis time that extended into the following morning.The species was self-incompatible. Floral visitors included moths, bees, and passerine birds. However, diurnalvisitors were more effective as pollinators than nocturnal ones. The flowers of E. leucantha were phenotypicallyspecialized (sphingophily); however, the pollination system was functionally and ecologically generalized. Theresults confirm that generalized pollination systems are widespread among species of the Echinopsis genus withnocturnal flowers, for which diurnal pollinators seem to have a key role in fruit and seed production. Our studyconstitutes the first record of passerine bird pollination in the Cactaceae for mainland South America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238335,"idioma_id":4,"titulo":"Tropical high Andean drylands: species diversity and its environmental determinants in the Central Andes","resumen":"Diversity determinants have mostly been evaluated in high diversity areas,leaving behind regions with less species diversity such as drylands. Here we aim to analyze the patterns of plant diversity in tropical drylands in the southern Central Andes, and determine the importance of water, energy, and environmental heterogeneity as diversity determinants of the arid and semi-arid adapted flora. We examined the distribution of 645 native species from lowlands to 6000 m.a.s.l. in the north-western region of Argentina (NWA) and define hotspots of diversity within each NWA ecoregion. Diversity is concentrated in regions of middle elevation with intermediate values of water and energy, at the transition between arid and semi-arid regions. Furthermore, we showed that in tropicaldrylands energy input is as fundamental for plant diversity as water input is and, we found that the effects of these variables varied with elevation and, also with aridity. Water variables had the strongest effect on the flora in the arid high Andean ecoregions, where an increase in precipitation during the growing season stimulated species diversity. Energy only became more important than water when the arid adapted flora entered the low and semi-arid regions where energy increments reduce species diversity. Our analysis provides strong quantitative support for climate variables as the main determinants of plant diversity across different ecoregions of the southern Central Andes. Given the present climate change events, knowing how these variables affect the distribution of the arid adapted flora is crucial for planning strategies for achieve their present and future conservation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238336,"idioma_id":4,"titulo":"Setting conservation priorities for Argentina's pseudocereal crop wild relatives","resumen":"Although the considerable value of cropwild relatives (CWRs) as gene donors is well known, in many crop complexes they are subject to increasing threats fromanthropogenic factors. The development of a prioritized inventory of CWR species is an essential step towards the conservation of this vital resource, so in this study, we developed a national inventory of pseudocereal CWRspecies in Argentina and established ex situ and in situ conservation priorities. The resulting prioritized inventory consisted of 16 species, almost all of which were underrepresented in national and global ex situ gene banks. Similarly, the extant reserve network was found to be insufficient for the preservation of pseudocereal CWRs, especially Chenopodium diversity. Three hotspot groupswere identified in the Andean region: northern, central and southern. The northern group has the highest conservation priority because it harbours CWR species from the primary and secondary gene pools, but the central and southern groups are also important because they harbour endemic species that are poorly represented in the extant reserve network. Therefore, new priority areas for protection are necessary for their conservation. This study emphasizes that the conservation of pseudocereal CWRs in Argentina must be maximized using acomplementary in situ and ex situ approach.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238338,"idioma_id":5,"titulo":"La razón y su envés. A propósito de la afectividad transcendental, las paradojas de la cultura y los fundamentos de la civilización en la filosofía de Kant","resumen":"CON-TEXTOS KANTIANOS.International Journal of Philosophy N.o 5, Junio 2017, pp. 503-507ISSN: 2386-7655Doi: 10.5281\/zenodo.807394La razón y su envés. A propósito de la afectividad transcendental, las paradojas de la cultura y los fundamentos de la civilización en la filosofía de KantReason and its Reverse. On the Transcendental Affectivity, the Paradoxes of Culture and the Grounds of Civilization in Kant?s PhilosophyMARCOS THISTED&#61623;Universidad de Buenos Aires, ArgentinaReseña de: Nuria Sánchez Madrid: A civilizaçao como destino: Kant e as formas da reflexão, Florianópolis, Nefiponline, 2016. 288 p. ISBN: 978-85-99608-16-6.A civilizaçao como destino: Kant e as formas da reflexão reúne trabajos ya publicados e inéditos de Nuria Sánchez Madrid, reconocida estudiosa de la antropología kantiana y sus vínculos con otras áreas del criticismo y más allá de él. Esta obra representa, sin lugar a dudas, una original contribución a los estudios kantianos, valiosa no sólo para quienes desean recorrer la filosofía crítica desde perspectivas aún poco exploradas, sino también para aquellos que procuran comprender el lugar prominente que ocupa el pensamiento kantiano en el contexto de la Aufklärung. Publicado en forma digital y accesible al público a través de Néfiponline (el sitio de publicaciones académicas de la Universidad Federal de Santa Catarina - Brasil), el libro se compone de una breve pero fundamental introducción y tres capítulos, cada uno integrado a su vez por tres apartados (originalmente, la mayoría de ellos fueron publicados como artículos en reconocidas revistas especializadas; tres de ellos, no obstante, son originales). Un prefacio de Leonel Ribeiro dos Santos, un postfacio de Márcio Suzuki y una actualizada selección bibliográfica correspondiente a cada capítulo completan la edición.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238339,"idioma_id":4,"titulo":"A Queer Approach to the Representations of Argentina's Recent Past: Anxieties around the Subjects of 'Our' History","resumen":"El artículo pretende aportar un análisis de un conjunto de representaciones públicas del pasado reciente argentino desde la perspectiva de una filosofía queer de la historia. En él se sostiene que tal enfoque provee valiosas herramientas para indagar cómo y por qué forjamos nuestro pasado como lo hacemos, cuál es el ?desorden? que la narrativa histórica con frecuencia intenta ?ordenar? y con qué mecanismos lo hace, y cómo se vincula todo ello con nuestros intereses presentes. Con este objetivo, se describen y analizan, en primer lugar, distintos mecanismos que se ponen en juego en la producción de representaciones acerca de los eventos liminales que conmovieron a la Argentina en los años 70, específicamente respecto a los modos en los que se selecciona, presenta y describe a lxs protagonistas de la resistencia al terrorismo de Estado. Finalmente, se propone leer estas prácticas de la memoria pública como fenómenos de ansiedad política, repensándolas a la luz de la potencia que nos ofrece una mirada queer.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238340,"idioma_id":5,"titulo":"Tres enfoques del pluralismo para la política del siglo XXI","resumen":"Desde diversos ámbitos de la teoría política contemporánea se ha llamado la atención sobre la necesidad de abordar, en todo análisis descriptivo o normativo de la política y lo político, las nociones y dificultades vinculadas con el pluralismo que caracteriza a las sociedades en las que vivimos. Este artículo tiene como objetivo aportar a dicha discusión una lectura crítica de tres abordajes considerablemente diferentes del tema: En torno a lo político (2005) de Chantal Mouffe, Political Liberalism (1996) de John Rawls, y Pluralism (2005) de William E. Connolly. Mediante un diálogo entre estos trabajos, sopesaremos sus fortalezas y debilidades y las proyectaremos hacia las posibilidades que brindan para comprender el fenómeno del pluralismo y llevar los aportes teóricos a la esfera práctica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238341,"idioma_id":4,"titulo":"The Sex-Gender-Revolution Series","resumen":"When carrying out political projects, the use of homosexual\/heterosexual or trans*\/cis distinctions as exclusive categories of analysis may limit our understanding of the complexity of belongings in which each subject is positioned. In many cases, including some queer approaches, this strategy provides for a simplification which attributes a radical or subversive nature to the first term of the pair and a normal or even repressive one to the second. The former case results in what is here called a 'homo-trans*-revolution series'; the latter, in a 'hetero-cis-repression series'. In both instances, a passage from generalization to reduction to invisibilization obstructs any understanding either of the conservative positions existent in the realm of the homo\/trans*, or of the subversive and radical ones in the sphere of the hetero\/cis. Exposing both of them will allow us to understand that a dissident, fertile collective political project cannot be based solely on sexuality or gender: it must build intersectional bridges based on political approaches and objectives, without falling into generalizations, and maintaining the flexibility we seek in queer approaches.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238342,"idioma_id":5,"titulo":"La naturalización del trabajo precario","resumen":"Si bien la tasa de desocupación tieneun comportamiento oscilante alrededor del 7% y 9%, de acuerdo a las estadísticasde los distintos trimestres de la Encuesta Permanente de Hogares, la preguntaque nos tenemos que hacer es la siguiente: ¿es suficiente el monitoreo de lacantidad de desocupados para poder afirmar empeoramientos y\/o mejoras en laocupación? Nuestra respuesta es no.La estructura social y económicaheterogénea de la Argentina nos muestra que otros fenómenos, tales como lasubocupación y la informalidad estructural, según los datos del tercertrimestre de 2016, han aumentado.Si bien hemos afirmado anteriormenteque el mero crecimiento económico no garantiza la resolución de los problemasestructurales, es una condición del entorno o un aspecto contextual necesariopara contener dichos problemas. La situación actual nos muestra que cuando esascondiciones del entorno empeoran, los indicadores del mercado de trabajo,dependientes de la fractura socio-productiva, tienden a agravarse con mayorrapidez.Dicho de manera simple, cuandonuestra economía crece, si no hay un proyecto de desarrollo social y económicode largo aliento, los problemas estructurales permanecen, quizás agazapados,pero esperando su momento. Si además de esta ausencia de proyecto de largoplazo las condiciones empeoran, el deterioro estructural será aún mayor. Uno deestos problemas lo venimos reflejando periódicamente en el indicador deinformalidad estructural.En este número queremos focalizarnosen las características de la persistencia de los problemas estructurales y, ala vez, señalar que, dentro del mercado de trabajo argentino, aquellostrabajadores y trabajadoras que tienen un empleo de calidad sólo representan lamitad de los ocupados de nuestro país.Este fenómeno es, precisamente, loque denominamos como la naturalización del trabajo precario, puesto que conhabitualidad se observan titulares respecto a la cantidad de personas que no tienentrabajo y a aquellos que teniéndolo, no están registrados. Sin dudas esto esimportante señalarlo pero el problema, lamentablemente, es mayor. O sea, existenotros segmentos socio-ocupacionales con graves problemas de precarización desus empleos, que intentaremos caracterizar en esta entrega.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238346,"idioma_id":4,"titulo":"A method for soil moisture probes calibration and validation of satellite estimates","resumen":"Optimization of field techniques is crucial to ensure high quality soil moisture data. The aim of the work is to present a sampling method for undisturbed soil and soil water content to calibrated soil moisture probes, in a context of the SMOS (Soil Moisture and Ocean Salinity) mission MIRAS Level 2 soil moisture product validation in Pampean Region of Argentina. The method avoids soil alteration and is recommended to calibrated probes based on soil type under a freely drying process at ambient temperature. A detailed explanation of field and laboratory procedures to obtain reference soil moisture is shown. The calibration results reflected accurate operation for the Delta-T thetaProbe ML2x probes in most of analyzed cases (RMSE and bias &#8804; 0.05 m3\/m3). Post-calibration results indicated that the accuracy improves significantly applying the adjustments of the calibration based on soil types (RMSE &#8804; 0.022 m3\/m3, bias &#8804; -0.010 m3\/m3).?A sampling method that provides high quality data of soil water content for calibration of probes is described.?Importance of calibration based on soil types.?A calibration process for similar soil types could be suitable in practical terms, depending on the required accuracy level.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238348,"idioma_id":4,"titulo":"Lung recruitment improves right ventricular performance after cardiopulmonary bypass","resumen":"Abstract:BACKGROUND: Atelectasis after cardiopulmonary bypass (CPB) can affect right ventricular (RV) performance by increasing its outflow impedance.OBJECTIVE: The aim of this study was to determine whether a lung recruitment manoeuvre improves RV function by re-aerating the lung after CPB.DESIGN: Randomised controlled study.SETTING: Single-institution study, community hospital, Córdoba, Argentina.PATIENTS: Forty anaesthetised patients with New York Heart Association class I or II, preoperative left ventricular ejection fraction at least 50% and Euroscore 6 or less scheduled for cardiac surgery with CPB.INTERVENTIONS: Patients were assigned to receive either standard ventilation with 6&#8202;cmH2O of positive end-expiratory pressure (PEEP; group C, n&#8202;=&#8202;20) or standard ventilation with a recruitment manoeuvre and 10&#8202;cmH2O of PEEP after surgery (group RM, n&#8202;=&#8202;20). RV function, left ventricular cardiac index (CI) and lung aeration were assessed by transoesophageal echocardiography (TOE) before, at the end of surgery and 30&#8202;min after surgery.MAIN OUTCOME MEASURES: RV function parameters and atelectasis assessed by TOE.RESULTS: Haemodynamic data and atelectasis were similar between groups before surgery. At the end of surgery, CI had decreased from 2.9&#8202;±&#8202;1.1 to 2.6&#8202;±&#8202;0.9&#8202;l min&#8722;1 m&#8722;2 in group C (P&#8202;=&#8202;0.24) and from 2.8&#8202;±&#8202;1.0 to 2.6&#8202;±&#8202;0.8&#8202;l min&#8722;1 m&#8722;2 in group RM (P&#8202;=&#8202;0.32). TOE-derived RV function parameters confirmed a mild decrease in RV performance in 95% of patients, without significant differences between groups (multivariate Hotelling t-test P&#8202;=&#8202;0.16). Atelectasis was present in 18 patients in group C and 19 patients in group RM (P&#8202;=&#8202;0.88). After surgery, CI decreased further from 2.6 to 2.4&#8202;l min&#8722;1 m&#8722;2 in group C (P&#8202;=&#8202;0.17) but increased from 2.6 to 3.7&#8202;l min&#8722;1 m&#8722;2 in group RM (P&#8202;<&#8202;0.001). TOE-derived RV function parameters improved only in group RM (Hotelling t-test P&#8202;<&#8202;0.001). Atelectasis was present in 100% of patients in group C but only in 10% of those in group RM (P&#8202;<&#8202;0.001).CONCLUSION: Atelectasis after CPB impairs RV function but this can be resolved by lung recruitment using 10&#8202;cmH2O of PEEP.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238353,"idioma_id":5,"titulo":"LA ?CASA DE LA CULTURA? COMO ELEMENTO DE ACTIVACIÓN PATRIMONIAL. EL CASO DE ESTUDIO DEL PUEBLO HISTORICO DE CONCEPCION DE LA SIERRA. MISIONES, ARGENTINA","resumen":"RESUMENEste trabajo tiene comoobjetivo principal presentar las actividades de extensión universitaria realizadasen la Casa de la Cultura, un espacio dedicado a actividades sociales ubicado enel pueblo de Concepción de la Sierra (provincia de Misiones). En primera instancia,presentamos un panorama general sobre el patrimonio arqueológico de lasreducciones jesuíticas- guaraníes de la provincia de Misiones, haciendohincapié en el área objeto de trabajo. Y desde este punto de partida, es queanalizamos el nombrado espacio cultural, en base a sus funciones y su relacióncon los elementos patrimoniales. A partir del Proyecto de investigación?Arqueología Histórica en Concepción de la Sierra: espacios reutilizados ymaterialidad arqueológica? el cual confiere a trabajos de investigaciónarqueológica, es que proponemos además una aproximación del patrimoniocotidiano y su articulación con los actores locales. Para esto, presentamos elenfoque teórico metodológico de ?activación patrimonial? como guía de análisis,e integrando las perspectivas de estudio de la arqueología y la museología, yde esta manera generar una mayor inclusión del patrimonio histórico local. Finalmente se discuten cuálesson las ventajas de generar actividades de difusión e integración de lostrabajos arqueológicos con la comunidad, y que pautas establecer para continuaren el mismo camino de articulación entre universidad y población local.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238354,"idioma_id":4,"titulo":"Taxonomic review of Argentine mackerel (Scomber japonicus (Houttuyn, 1782) by phylogenetic analysis","resumen":"Taxonomically, Argentine mackerels were first considered as Scomber japonicusmarplatensis and later as Scomber japonicus Houttuyn 1782, although, in the last years, different studies have suggested that South Atlantic mackerel species belongs to Scomber colias Gmelin 1789. These latter results, incorporated in the main fish databases (FishBase and Catalog of Fishes), promoted a phylogenetic study using cytochrome c oxidase I (COI) gene sequences taken from the Barcode of Life (FISHBOL) database. Thus, 76 sequences of S. japonicus, S. colias, S. australasicus and S. scombrus from different regions were used; including 3 from Sarda sarda as outgroup. Among S. japonicus selected sequences are those corresponding to the Argentine mackerels collected in 2007. Phylogenetic trees were obtained by neighbor joining and maximum likelihood methods and a network of haplotypes was reconstructed to analyze the relationship between species. The results showed the clear differentiation of S. australasicus, S. scombrus and S. japonicus from the Pacific while S. japonicus from Argentina was included in the S. colias group, with genetic differences corresponding to conspecific populations (0.1%). Four of the five Argentine specimens shared the same haplotype with S. colias, and none were shared with S. japonicus from the Pacific. These results suggest that the current specific name of Argentine mackerel S. japonicus should be changed to S. colias, in agreement with several genetic studies carried out with species of the genus Scomber.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238355,"idioma_id":4,"titulo":"Rat Brain Damage due to Iron and Copper Toxicity","resumen":"AbstractBrain damage is associated to oxidative stress in iron (Fe) and copper (Cu)overloads in rats, in a dose- and time-dependent accumulation of the metals inthe organ. The generation of singlet oxygen in brain measured in vivo by in situchemiluminescence indicates that Fe and Cu overloads increased phospholipidand protein oxidation, and decreased non enzymetic endogenous antioxidantscontent in the organ, mainly glutathione (GSH). These results fit with a Fenton\/Haber-Weiss type reaction between iron, copper and endogenously producedsuperoxide anion (O2?-) and hydrogen peroxide (H2O2) to yield hydroxyl radical(OH?), as well as reactions involving thiol groups of GSH and proteins.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238359,"idioma_id":4,"titulo":"Effect of honey on the rheological and textural properties of carrageenan-locust bean gum mixed gel systems","resumen":"The purpose of this study was to evaluate the influence of honey on the rheological and textural properties of mixed polysaccharide gel systems, as a first step to develop a honey-based food product mimicking a commercial vegetable gelatin dessert. Polysaccharides used as gelling and texturizing agents were &#954;-carrageenan and locust bean gum. The profiles of the textural and rheological parameters of the obtained product with honey were similar to those of a commercial product (vegetable gelatin), showing a typical behaviour of polysaccharide gels. However, the gelation and melting temperatures were higher for the former. No significant differences were observed in Bloom strength of honey-based and commercial gels. In addition, honey modified texture parameters and retarded syneresis. The product has significant amounts of honey and exhibitproperties that make it attractive for the formulation of commercial food gels.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238360,"idioma_id":4,"titulo":"Chemometrics and multielement techniques for honey geographic origin","resumen":"In this work, proximal and mineral profile of multifloral honeys from selected regions of Argentina, Portugal, and Angola were determined and related to its geographical origin. Moisture, °Brix sugar, ash, pH, aw and minerals were determined by AOAC methods. Chemometrics supervised, and nonsupervised patterns recognition were applied to construct classification\/discrimination rules to predict the origin of samples on the basis of their parameter physicochemical and mineral content. Namely PCA, HCA, LDA, KNN and SVM. Physicochemical analysis showed the high quality of tested samples. Between minerals, K was the most abundant in all samples, ranging from 363.26-2034.11 mg\/kg followed by a lesser amount P varies between 45.43-115.63 mg\/kg, while Cu was the least abundant 0.18-2.02 mg\/Kg. Results showed differences in composition and mineral profile among the honeys from different regions. The first three principal components explained more than 67% of the variance with minerals having highest discriminating power while HCA successfully classified the honey samples. Results indicated that it was feasible to attribute unknown honey to its geographical origin. SVM had better performance compared to KNN and LDA. Eventually, this study verifies that mineral content is a powerful geographic indicator for the identification of honey origin with the help of SVM technique.  The reliability of classification of chemometrics methods changes (increases or decreases) when the uncertainty is increased. The use chemometrics methods with the evaluation of proximate and mineral contents revealed that the obtained data could be applied as a contribution to the honey quality and authenticity determination.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238362,"idioma_id":4,"titulo":"Pharmacological treatment with cabergoline in three cats with 7 acromegaly","resumen":"Anamnesis: three cats diagnosed with diabetes mellitus (DM) were referred for 13 examination due to the presence of insulin resistance signs, which included polyuria, 14 polydipsia, polyphagia and high fructosamine levels, even with insulin glargine doses greater 15 than 2 U\/kg per application. Clinical and laboratory findings: all patients had enlarged 16 facial features along with an increase in interdental space. The biochemical tests revealed 17 high IGF-1 concentrations. The MRI displayed an enlarged pituitary gland in one of the cats 18 and images compatible with a pituitary macroadenoma in the other two. Acromegaly was the 19 final diagnosis. Therapeutic approach: Oral cabergoline at 10 &#956;g\/kg every 48 hours. 20 Conclusion: the treatment with cabergoline successfully decreased IGF-1 concentrations and 21 all insulin resistance signs, and it enhanced glycemic control for the DM in the three cats. 22 Previous findings evidence that cabergoline is a feasible option for the treatment of 23 acromegaly in cats.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238363,"idioma_id":4,"titulo":"Concurrent hyperadrenocorticism and diabetes mellitus in dogs","resumen":"Hyperadrenocorticism (HAC) and diabetes mellitus (DM) are two diseases that can occur concurrently in dogs. The objective of this study was to evaluate the coexistence of HAC and DM, and the risk factors involved that could contribute to the development of DM in dogs with HAC. A total of 235 dogs with HAC were studied and, according to their fasting glycemia, they were divided into three groups: 10.08mmol\/L. The following parameters were evaluated: age, gender, cause of HAC, body condition, glycemia, total cholesterol, triglycerides, urinary cortisol:creatinin ratio (UCCR) and survival time. A 13.61% concurrence of HAC and DM was observed. Dogs with a fasting glycemia >5.6mmol\/L, with dislipemia, with Pituitary-Dependent Hyperadrenocorticism, UCCR >100×10-6 and non-castrated females showed a higher risk of developing DM. The development of DM in dogs with HAC reduces the survival time.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238365,"idioma_id":5,"titulo":"LA FORMACIÓN DE PROFESORES DE CIENCIAS: DESCRIPCIÓN Y ANÁLISIS DE POSIBLES RELACIONES ENTRE LAS REPRESENTACIONES SOBRE EL APRENDIZAJE DE DOCENTES Y ESTUDIANTES UNIVERSITARIOS DE PROFESORADO","resumen":"ResumenEl cambio educativo no solo requiere de modificaciones curriculares sino también de la reflexión de los docentessobre sus propias concepciones sobre el aprendizaje y la enseñanza, ya que estas determinan su relación con elconocimiento y la práctica docente, cuestión que adquiere especial relevancia en la formación de futurosprofesores. Este trabajo aporta los resultados de la caracterización y el análisis de posibles relaciones entre lasconcepciones implícitas sobre el aprendizaje de docentes y estudiantes universitarios de profesorados en ciencias.Se realizó un estudio descriptivo de la variable Concepciones sobre el aprendizaje, con 167 participantes de laUniversidad Nacional de Mar del Plata, Argentina. El tratamiento de los datos se realizó a través del análisisdescriptivo univariado y multivariado. Los resultados reflejan que cada sujeto convive con diferentesconcepciones simultáneas en función del contexto, observándose similitudes y diferencias entre las concepcionesde cada grupo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238368,"idioma_id":4,"titulo":"Trypsin and N-aminopeptidase (APN) activities in the hepatopancreas of an intertidal euryhaline crab: Biochemical characteristics and differential modulation by histamine and salinity","resumen":"No studies are available about biochemical characteristics and modulation (i.e. by endogenous and\/orenvironmental cues) of trypsin (a key digestive endoprotease) in hepatopancreas of intertidal euryhalinecrabs neither on the possible concomitant modulation of key ectoproteases such as aminopeptidase-N (APN)involved in final steps of protein digestion. Furthermore, nothing is still known in decapods crustaceansabout the role of histamine as primary chemical messenger for modulation of main components of digestiveprocess (i.e. proteases). We determined biochemical characteristics and investigated the effect of histamineinjections; of histamine in vitro and of acclimation of individuals to low and high salinity on trypsin andaminopeptidase-N (APN) activities in the hepatopancreas of the euryhaline crab Cyrtograpsus angulatus(Dana 1851). Trypsin activity was maximal at pH 7.4 and at 45°C. APN activity increased from pH 6.6 to7.6-9.0 and was maintained high at 37-45°C. Both activities exhibited Michaelis-Menten kinetics (apparentKm: trypsin= 0.36 mM; APN=0.07 mM). The injection of 10-4M histamine decreased trypsin activity (about40 %) in hepatopancreas while did not affect APN activity. Similarly, in vitro 10-4M histamine decreasedtrypsin activity (about 52%) in hepatopancreas but not APN activity. Trypsin activity in the hepatopancreaswas not affected by acclimation of crabs to low (10 psu) or high (40 psu) environmental salinity while APNactivity was increased (about 200%) in 10 psu. The results show the differential modulation of trypsin andAPN by distinct cues and point to histamine as modulator of intracellular trypsin by direct action on thehepatopancreas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238369,"idioma_id":5,"titulo":"¿Sueñan los sociólogos con nuevas teorías?","resumen":"Se trata de una introducción al dossier 'Nuevas perspectivas de la teoría sociológica y social contemporánea', coordinado por Alejandro Bialakowsky y Mariano Sasín. Allí, se señala el escenario en el cual se despliegan tales nuevas perspectivas, a partir de su distanciamiento con la generación previa de teóricos. También, se resaltan ciertos tópicos claves para las nuevas propuestas. Por último, se pasa revista a los artículos publicados en el Dossier, al remarcar algunos puntos de contacto y ejes de debates que indican afinidades y divergencias.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238370,"idioma_id":5,"titulo":"Investigar teoría sociológica del Sur y del Norte: la propuesta del abordaje simultáneo","resumen":"Este ensayo propone una metodología para abordar simultáneamente perspectivas de la teoría sociológica del 'Sur' y del 'Norte', a través de sus problemas y sus dimensiones emergentes. Para ello, se pretende evitar los dispositivos de 'distanciamiento temporal' entre 'Sur y 'Norte', ya sean los que señalan un supuesto 'retraso' del Sur respecto del Norte en los estudios de 'recepción', ya sean los que afirman un mero 'relativismo cultural' entre las elaboraciones de ambas regiones. Esto posibilita analizar, en un mismo plano, distintos aportes a la teoría sociológica desde ciertas 'encrucijadas teóricas y epocales' de una modernidad simultánea y desigual.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238373,"idioma_id":5,"titulo":"¿Teorías sin teoría? Tras las huellas del primer pragmatismo en las perspectivas de Archer, Boltanski, Honneth y Latour","resumen":"Frente a la generación de autores como Habermas, Luhmann, Giddens o Bourdieu, desde distintas miradas, Archer, Boltanski, Honneth y Latour han renovado los presupuestos y análisis de la teoría sociológica contemporánea. A pesar de una aparente disimilitud y distancia de sus propuestas, todas ellas han abrevado de forma fundamental en el 'primer pragmatismo' norteamericano de Peirce, James y Dewey. Por tanto, con el objetivo de plasmar una mirada abarcativa multidimensional, este artículo rastrea las huellas del 'primer pragmatismo' en las propuestas de Archer, Boltanski, Honneth y Latour, a partir de cinco dimensiones claves: la crítica a las dicotomías del pensamiento sociológico; el despliegue de una metodología como resolución de problemas prácticos; el estudio de la relaciones entre creencias, experiencias y efectos prácticos; la investigación de las modalidades a través de las cuales se forman grupos reales, que no pueden darse por sentado; y, por último, la intervención político-práctica entendida como ensanchamiento del mundo. Esto permite no sólo señalar la centralidad actual del pragmatismo en la teoría sociológica, sino también dar cuenta de las múltiples dimensiones desde las cuales se lo puede abordar. Asimismo, tales análisis obligan a discutir en que medida estas propuestas continúan o no el proyecto de elaborar teorías sociológicas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238374,"idioma_id":5,"titulo":"La temporalidad y la contingencia en el 'giro del sentido' propuesto por las perspectivas teóricas de Giddens, Bourdieu, Habermas y Luhmann","resumen":"Este artículo analiza el 'giro del sentido' propuesto por las perspectivas de Giddens, Bourdieu, Habermas y Luhmann, desde sus dimensiones centrales: la contingencia y la temporalidad. Así, se estudia cómo estos autores postulan al 'sentido' como condición de posibilidad emergente y procesual de lo social marcado por la contingencia. Asimismo, se rastrean sus propuestas sobre la temporalidad, las cuales sostienen que lo social no es mera contingencia: mediante la misma temporalidad lo social se vuelve 'recursivo' o 'probable'. Por ende, con una teorización del tiempo, este giro del sentido articula lo impredecible de lo social y su acontecer efectivo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238375,"idioma_id":5,"titulo":"El abordaje problemático como metodología para la investigación en teoría sociológica y el análisis de las clasificaciones sociales","resumen":"Desde una reflexión teórica, epistemológica y metodológica, este ensayo propone al 'abordaje problemático' como metodología para investigar en teoría sociológica. Para esto, se retoman críticamente las postulaciones de Alexander sobre su multidimensionalidad y las de Ritzer acerca de su carácter multiparadigmático. Allí, se señalan ciertos reduccionismos en sus elaboraciones que interpretan a la teoría sociológica desde algunas dicotomías clásicas. En cambio, el abordaje problemático permite dar cuenta de la pluralidad de problemas, presupuestos y análisis que van transformando a la teoría sociológica, la cual tampoco se recorta únicamente por conceptos. Así, se trazan dimensiones y niveles de un problema, que habilitan a comparar perspectivas. Tal trazado es el resultado de un análisis emergente, que las delimita desde los mismos planteos de las perspectivas, al evitar un estudio 'interno', clausurado en un autor, o 'externo?, que las interpreta desde una supuesta perspectiva 'superadora'. Asimismo, este abordaje y su análisis emergente se ponen a prueba con el problema de las clasificaciones sociales, en el cual se detectan dos dimensiones (tipológica-histórica y jerárquica), atravesadas por dos niveles (representacional y epistemológico-político). El concepto de reclasificaciones sociológicas, como proceso que reclasifica clasificaciones sociales en general, permite una mirada reflexiva sobre la teoría y sus dicotomías.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238378,"idioma_id":5,"titulo":"Consideraciones anatomo-fisiológicas para el uso prudente de fármacos en conejos","resumen":"Las cabras son animales gregarios que viven en manadas, adaptados a pastorear y a ramonear en ambientes muy secos y\/o montañosos y se han adaptado a diversos sistemas ecológicos, algunos de ellos muy frágiles, ubicados en zonas áridas y semiáridas, donde los suelos poseen bajo contenido en materia orgánica y nutrientes. Los principales productos obtenidos son carne, leche y fibra. España es el segundo país de la Unión Europea con más existencias de ganado caprino. Dado que existe poca información sobre regímenes posológicos de diferentes fármacos en la especie caprina, en el ámbito clínico es común extrapolar datos provenientes de diferentes especies de rumiantes, como bovinos u ovinos, lo que podría conducir a un fallo terapéutico, aumentar la toxicidad, promover la aparición de resistencia antimicrobiana y antiparasitaria y la presencia de residuos de medicamentos en productos de origen animal. De esta manera, el objetivo de esta publicación es describir algunas características anatómicas y fisiológicas de la especie caprina que pueden determinar diferencias en el comportamiento farmacocinético y farmacodinámico de algunos fármacos utilizados en esta especie.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238379,"idioma_id":4,"titulo":"Topological Kondo insulators in one dimension: Continuous Haldane-type ground-state evolution from the strongly interacting to the noninteracting limit","resumen":"We study, by means of the density-matrix renormalization group (DMRG) technique, the evolution of the ground state in a one-dimensional topological insulator, from the noninteracting to the strongly interacting limit, where the system can be mapped onto a topological Kondo-insulator model. We focus on a toy model Hamiltonian (i.e., the interacting ?sp-ladder? model), which could be experimentally realized in optical lattices with higher orbitals loaded with ultracold fermionic atoms. Our goal is to shed light on the emergence of the strongly interacting ground state and its topological classification as the Hubbard U interaction parameter of the model is increased. Our numerical results show that the ground state can be generically classified as a symmetry-protected topological phase of the Haldane type, even in the noninteracting case U=0 where the system can be additionally classified as a time-reversal Z2-topological insulator, and evolves adiabatically between the noninteracting and strongly interacting limits.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238380,"idioma_id":4,"titulo":"Topological Kondo insulators in one dimension: Continuous Haldane-type ground-state evolution from the strongly interacting to the noninteracting limit","resumen":"We study, by means of the density-matrix renormalization group (DMRG) technique, the evolution of the ground state in a one-dimensional topological insulator, from the noninteracting to the strongly interacting limit, where the system can be mapped onto a topological Kondo-insulator model. We focus on a toy model Hamiltonian (i.e., the interacting ?sp-ladder? model), which could be experimentally realized in optical lattices with higher orbitals loaded with ultracold fermionic atoms. Our goal is to shed light on the emergence of the strongly interacting ground state and its topological classification as the Hubbard U interaction parameter of the model is increased. Our numerical results show that the ground state can be generically classified as a symmetry-protected topological phase of the Haldane type, even in the noninteracting case U=0 where the system can be additionally classified as a time-reversal Z2-topological insulator, and evolves adiabatically between the noninteracting and strongly interacting limits.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238381,"idioma_id":4,"titulo":"Grassland connectivity explains entomophilous plant species assemblages in an agricultural landscape of the Pampa Region, Argentina","resumen":"The Pampa grassland of Argentina is one of the most highly threatened biomes in the world. A high proportion of the original grassland cover has been transformed into land for agriculture or degraded. In the southern part of the region, fragmented semi-natural grasslands over exposed rock still persist and connectivity between them is assumed to be crucial for maintaining viable populations. We quantified overall connectivity of grassland patches in a sector of the Southern Pampa region, and investigated the degree to which landscape connectivity explains entomophilous plant species assemblages in a subset of patches. We characterized each of the 301 patches in the landscape by their degree of intra-patch and inter-patch connectivity based on graph theory, and considering threshold dispersal distances from 100 to 1000 m. We surveyed entomophilous plant species in 39 grassland patches and classified the species in three categories (annual herbs, perennial herbs and shrubs) considering their different growth form and longevity. The influence of connectivity variables on entomophilous plant species assemblages variation was explored using Canonical Correspondence Analysis. Although grassland patches were poorly connected at all threshold distances, some of them were found to be critical for global connectivity. Connectivity significantly explained total, annual-biennial and shrub assemblages for all threshold dispersal distances (6-13% of total variation). Variation in annual species assemblages was associated with intra-patch and inter-patch connectivity at short distance (100 m), while variation in shrub species assemblages was explained by intra-patch and inter-patch connectivity for distances between 100 m and 1000 m. This study evidenced the low connectivity of the study system, allowed the identification of critical areas for conservation, and provided valuable information to develop management strategies in increasingly human-dominated landscapes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238382,"idioma_id":4,"titulo":"Cold sweetening diversity in Andean potato germplasm from Argentina","resumen":"BACKGROUND: Cold-induced sweetening (CIS) is the accumulation of sucrose and reducing sugars in potato tubers at low temperatures. This process is central for the potato processing industry. During potato chip and French fry production, reducing sugars participate in the Maillard reaction to produce dark pigmented products not acceptable to consumers. Andean potatoes (Solanum tuberosum Group Andigena) constitute an enormous wealth of potato germplasm that can contribute to increase genetic diversity in breeding programs of many traits, including CIS. RESULTS: We analyzed reducing sugar content and chip quality in freshly harvested and cold-stored tubers from 48 native accessions. Andean accessions showed high variation in reducing sugar content and were classified in three types of CIS responses: type I, reducing sugar content before and after 4&deg;C storage was lower than the value required by industry; type II, reducing sugar content before storage was acceptable, but after 4&deg;C storage incremented up to non-acceptable levels; and type III, reducing sugar content was unacceptable before and after storage. CONCLUSION: Five Andean accessions presented acceptable reducing sugar content and good chip quality before and after 4&deg;C storage in a consistent manner throughout several experiments. These features make them a useful source for improving the potato industry.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238386,"idioma_id":4,"titulo":"Morphological and molecular evidence for a new species of Pseudanisakis Layman &amp; Borovkova, 1926 (Nematoda: Ascaridida), parasitizing Rajiformes in southern Southwest Atlantic waters","resumen":"Pseudanisakis argentinensis n. sp. is proposed to accommodate parasitic nematodes found in six skate species (Rajidae and Arhynchobatidae) examined from southern Southwest Atlantic waters. The new species differs from its congeners by the following combination of characters: a cupola on each lip, males with 8?12 pairs of precloacal genital papillae, a larger size for both males and females, a greater length-to-breadth ratio of the ventriculus and the presence of a small knob on the tip of the tail. Allometric growth was observed for several morphometric features; however, the slopes of the allometric relationships across host species exhibited non-significant differences and were considered as a strong evidence for conspecificity. Congruent results were obtained after the genetic characterization of the mitochondrial cytochrome c oxidase subunit 1 gene of worms obtained from different skate species, whose values of genetic divergence (1.3) lay within the range of intraspecific variation. Previous records of specimens referred to as Pseudanisakis tricupola in skates from South American waters are regarded as conspecific with P. argentinensis n. sp.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238387,"idioma_id":4,"titulo":"Evaluating the usefulness of natural tags for host population structure in chondrichthyans: Parasite assemblages of Sympterygia bonapartii (Rajiformes: Arhynchobatidae) in the Southwestern Atlantic","resumen":"The usefulness of parasite tags for population discrimination of elasmobranch hosts remains largely unexplored. In order to assess the existence of different populations of Sympterygia bonapartii in the Southwestern Atlantic using its parasites as biological tags and to evaluate their usefulness as indicators for chondrichthyan hosts, we analysed data on assemblages of both long-lived and short-lived parasites of 193 skates distributed in eight samples caught at different seasons, years, depths and latitudes. A total of 6527 metazoan parasites, belonging to 19 species, was recorded. Only three species were long-lived, being therefore suitable biological tags, and they were used to assess the population structure of S. bonapartii. As a result, three host populations were identified (one Bonaerensean and two Patagonian). Distance-based multiple linear regressions (DistLM) evidenced that latitude was the most important predictor of parasite distribution, confirming the value of long-lived species as biological tags. When short-lived parasites were analysed, most samples differed from each other. Furthermore, a bathymetric rather than a latitudinal pattern was observed across samples, which was associated with reproductive migrations displayed by S. bonapartii. DistLM analyses showed that depth and year were almost as important as latitude as predictors of parasite distribution. This proves the little value of this guild as indicators of host population structure. Transient parasites could be acceptable to study seasonal migrations of their hosts, but it is recommended to avoid their use as tags for population assessment, either alone or combined with long-lived species. This is especially relevant for elasmobranch hosts, for which the numerical dominance of short-lived species in their parasite assemblages is the rule. Based on these results, and upon a careful selection of suitable species, we recommend using parasites as reliable and robust sources of information that provide significant data for the implementation of management measures that ensure the conservation, recovery and sustainable use of elasmobranchs under exploitation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238389,"idioma_id":4,"titulo":"From the classroom to an opinion note: Complementary analysis of the genetic structure of the neotropical tree Manilkara zapota (L) P. Royen (Sapotaceae)","resumen":"Here, we describe a learning strategy that results an excellent choice for a first approach of students to produce scientific knowledge that can be confronted in the scientific field as well as recognize in this knowledge the transferability to the natural resources management. Nowadays, the availability of several Population Genetics software together with public molecular database represents a valuable tool of great assistance for teachers of this discipline. In this way, we implemented a lecture where the students worked with empirical data set from a recent published article. The students joined theoretical concepts learned, computational software free available and empirical data set. The development of the activity comprised four steps: i) estimate population genetics parameters using software recommended by teachers, ii) understand results in a biological sense, iii) read the original manuscript from dataset authors and iv) compare both results in a comprehensive way. The students assumed the challenge under a reflective look and they kept a very fruitful discussion playing a role of population geneticists. Their exchange of ideas allowed them arrive to the conclusion that Manilkara zapota populations keep high levels of genetic diversity, although Ancient Maya left traces in the genetic makeup of these non-native populations with different management histories","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238391,"idioma_id":4,"titulo":"Petrogenesis of volcanic rocks that host the world-class AgPb Navidad District, North Patagonian Massif: Comparison with the Jurassic Chon Aike Volcanic Province of Patagonia, Argentina","resumen":"We present the first study of the volcanic rocks of the Cañadón Asfalto Formation that host the Navidad world-class Ag + Pb epithermal district located in the North Patagonian Massif, Patagonia, Argentina. These volcanic and sedimentary rocks were deposited in a lacustrine environment during an extensional tectonic regime associated with the breakup of Gondwana and represent the mafic to intermediate counterparts of the mainly silicic Jurassic Chon Aike Volcanic Province. Lava flows surrounded by autobrecciated carapace were extruded in subaerial conditions, whereas hyaloclastite and peperite facies suggest contemporaneous subaqueous volcanism and sedimentation. LA-ICPMS UPb ages of zircon crystals from the volcanic units yielded Middle Jurassic ages of 173.9 ± 1.9 Ma and 170.8 ± 3 Ma. In the Navidad district, volcanic rocks of the Cañadón Asfalto Formation show arc-like signatures including high-K basaltic-andesite to high-K dacite compositions, Rb, Ba and Th enrichment relative to the less mobile HFS elements (Nb, Ta), enrichment in light rare earth elements (LREE), YTi depletion, and high Zr contents. These characteristics could be explained by assimilation of crustal rocks in the Jurassic magmas, which is also supported by the presence of zircon xenocrysts with Permian and Middle-Upper Triassic ages (281.3 Ma, 246.5, 218.1, and 201.3 Ma) and quartz xenocrysts recognized in these volcanic units. Furthermore, Sr and Nd isotope compositions suggest a contribution of crustal components in these Middle Jurassic magmas. High-K basaltic andesite has initial 87Sr\/86Sr ratios of 0.70416?0.70658 and &#958;Nd(t) values of -5.3 and -4. High-K dacite and andesite have initial 87Sr\/86Sr compositions of 0.70584?0.70601 and &#958;Nd(t) values of -4,1 and -3,2. The range of Pb isotope values (206Pb\/204Pb = 18.28?18.37, 207Pb\/204Pb = 15.61?15.62, and 208Pb\/204Pb = 38.26?38.43) of Navidad volcanic rocks and ore minerals suggest mixing Pb sources with contributions of mantle and crust. 206Pb\/204Pb isotopic ratios of Jurassic volcanic rocks of the Chon Aike Volcanic Province and sulfides of associated epithermal deposits increase with time from the volcanic event V1 (188?178 Ma) to volcanic events V2 (172?162 Ma) and V3 (157?153 Ma), reflecting variations in the radiogenic Pb source as volcanism was migrating towards the Proto Pacific margin of Gondwana","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238395,"idioma_id":4,"titulo":"Learning from Synthetic Models of Extracellular Matrix; Differential Binding of Wild Type and Amyloidogenic Human Apolipoprotein A-I to Hydrogels Formed from Molecules Having Charges Similar to Those Found in Natural GAGs","resumen":"Among other components of the extracellular matrix (ECM), glycoproteins and glycosaminoglycans (GAGs) have been strongly associated to the retention or misfolding of different proteins inducing the formation of deposits in amyloid diseases. The composition of these molecules is highly diverse and a key issue seems to be the equilibrium between physiological and pathological events. In order to have a model in which the composition of the matrix could be finely controlled, we designed and synthesized crosslinked hydrophilic polymers, the so-called hydrogels varying the amounts of negative charges and hydroxyl groups that are prevalent in GAGs. We checked and compared by fluorescence techniques the binding of human apolipoprotein A-I and a natural mutant involved in amyloidosis to the hydrogel scaffolds. Our results indicate that both proteins are highly retained as long as the negative charge increases, and in addition it was shown that the mutant is more retained than the Wt, indicating that the retention of specific proteins in the ECM could be part of the pathogenicity. These results show the importance of the use of these polymers as a model to get deep insight into the studies of proteins within macromolecules.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238396,"idioma_id":5,"titulo":"El éxito de la Teletón en Chile: paradoja y mensaje en la era de los derechos","resumen":"En la actualidad se acepta que la discapacidad es una cuestión social y de derechos. La Convención Internacional sobre los Derechos de las Personas con Discapacidad firmada ante Naciones Unidas en el 2006 es considerada el marco que cristaliza este acuerdo y que consagra un cambio de paradigma al desmantelar respuestas biologicistas y caritativas. Sin embargo, en Chile, pese a que este país incorporó este instrumento internacional, discapacidad es sinónimo de rehabilitación y solidaridad a raíz del protagonismo cultural e histórico que posee una campaña benéfica televisada llamada Teletón. El principal aporte de este artículo es sugerir que esta paradoja posee un mensaje por descifrar respecto a la situación de discapacidad actual, el cual emerge al reconstruir el tipo de estructuración y de relaciones sociales que la hacen posible. Para develar este mensaje, se parten de los aportes de un conjunto heterogéneo de estudios provenientes de las Ciencias Sociales y del material empírico reunido en una investigación cualitativa realizada en Chile entre 2014 y 2016 sobre políticas, discapacidad y prácticas caritativas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238401,"idioma_id":5,"titulo":"Los discursos público-mediáticos de los núcleos eclesiásticos frente al fenómeno del menemismo en la etapa de sedimentación del orden neoliberal","resumen":"Este trabajo analiza los posicionamientos políticos de los núcleos eclesiásticos frente al fenómeno del menemismo, durante la etapa de sedimentación del orden neoliberal. Desde una perspectiva de análisis sociopolítico del discurso, coloca el eje en los posicionamientos públicos en torno a las reformas neoliberales, la estabilidad monetaria y la cuestión social. Se identificaron dos posiciones divergentes sobre el modelo económico y social que, sin embargo, no cuestionaban a las reformas neoliberales y compartían el apoyo explícito o tácito al punto nodal de la hegemonía menemista. Ello obturaba la construcción de un proyecto alternativo al orden neoliberal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238404,"idioma_id":5,"titulo":"Tumor Odontogenico Adenomatoide. Reporte de un Caso Clinico","resumen":"El tumor odontogénico adenomatoide (TOA) es una lesión benigna, infrecuente, clasi&#64257; cada por la OMS dentro de los tumores odontogénicos con participación del ectomesénquima que muestra una morfología histológica muy peculiar. Esta entidad patológica es de baja prevalencia, representa 0.1% de los tumores y quistes de los maxilares con raras recidivas. Su frecuencia de aparición es más común en pacientes jóvenes, generalmente mujeres, de mayor aparición en maxilar superior, asintomático, asociado a dientes sin erupcionar (principalmente caninos) que plantea diagnósticos diferenciales entre otras lesiones de mayor agresividad como el quiste dentígero y el ameloblastoma. Se presenta el caso de una paciente de nueve años de edad con lesión tumoral en el sector del maxilar superior izquierdo de 40 días de evolución. Clínicamente hay ausencia del órgano dentario número 23. Se indica la realización de una radiografía panorámica, en la cual se observa la presencia del órgano dental 23 en el piso de órbita del maxilar superior izquierdo. Se procede a la remoción quirúrgica con diagnóstico presuntivo de quiste dentígero, se biopsia el total de la lesión, con diagnóstico de&#64257; nitivo por histopatología de TOA con buena evolución clínica odontológica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238405,"idioma_id":5,"titulo":"Las principales entidades agropecuarias de la Argentina en la etapa previa al orden neoliberal. Posicionamientos políticos, disputas en torno al modelo económico y social y eficacia interpelativa","resumen":"Este trabajo realiza una reconstrucción y análisis de las discursividades y las disputas por la hegemonía en las principales corporaciones agropecuarias, durante la etapa inmediatamente previa a la emergencia de la hegemonía neoliberal en la Argentina. A partir del análisis sociopolítico de los discursos de las principales organizaciones del agro a nivel nacional y de sus referentes institucionales claves, desde un enfoque posestructuralista y posmarxista, se examinan los posicionamientos, las disputas en torno almodelo económico y social y la dimensión del impacto hegemónico, durante 1988. Se concluye que la implementación del Plan Primavera y las interpelaciones oficiales tuvieron un efecto de redefinición de posiciones que radicalizó las críticas de las principales corporaciones agrarias y generó una articulación defensiva contra el programa económico del gobierno de Alfonsín. Esta convergencia se extendió desde el plano verbal a las prácticas sociales e institucionales de las cuatro entidades más importantes del agro, contribuyendo a explicar el fracaso del alfonsinismo y el avance de las políticas neoliberales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238406,"idioma_id":5,"titulo":"Decisiones y estrategias metodológicas para la investigación social empírica desde la Teoría Política del Discurso","resumen":"La Teoría Política del Discurso de Ernesto Laclau aportó valiosas contribuciones para el análisis discursivo de las identidades políticas, la construcción de hegemonías y las formas ideológicas. Sin embargo, a diferencia de otras perspectivas de análisis del discurso, carece de una metodología propia para la investigación social. Este trabajo aporta algunos recursos que procuran contribuir a la construcción de una metodología rigurosa y útil para el análisis sociopolítico del discurso y la investigación crítica en Ciencias Sociales. De manera particular, examina algunos problemas iniciales que debe afrontar el analista del discurso y algunas opciones, decisiones y estrategias metodológicas para elaborar una investigación social empírica. Se analizan cuatro problemas metodológicos, que se vinculan a las decisiones y estrategias para la construcción del ?objeto? de la investigación (lo que incluye la elección y justificación del tema, los objetivos, preguntas e hipótesis), el recorte del corpus, la elección y justificación de las fuentes y de los agentes-participantes, enfocando en el análisis discursivo-textual.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238407,"idioma_id":5,"titulo":"La construcción político-discursiva del liderazgo de Fernando De la Rúa en la última etapa de su Gobierno","resumen":"Este trabajo analiza la construcción político-discursiva del liderazgo de Fernando De la Rúa, colocando el eje en su discurso de apertura de sesiones ante la Asamblea Legislativa del año 2001. En la primera parte elabora una conceptualización propia para el análisis sociopolítico del discurso presidencial, a partir de una articulación de herramientas de la teoría discursiva de la hegemonía, la semiótica social francesa y teorías del liderazgo y la comunicación gubernamental. En la segunda parte desarrolla un análisis histórico-político del contenido y de la modalidad enunciativa del discurso presidencial. A partir del análisis empírico se concluye que De la Rúa delimitaba una frontera de exclusión frente al menemismo a nivel económico y político-institucional, aunque manteniendo incuestionado el núcleo nodal del orden neoliberal. Desde una lógica eficientista y asistencialista, promovía la radicalización de las reformas y ajustes ortodoxos y adoptaba la Teoría del Derrame a nivel social. Desde el lado enunciativo el contraste con la estética menemista asumía una forma más radicalizada y general. De la Rúa adoptaba un ethos austero y responsable, desde un tono moralista que presentaba una modalidad deontológica, una estrategia dialógica y un estilo serio y formal. Dicha escenificación discursiva era coherente con la construcción biográfica y con la imagen pública proyectada, y su condensación en torno al significante austeridad le permitía legitimar la profundización de las políticas ortodoxas y la conservación de los fundamentos del modelo de Convertibilidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238409,"idioma_id":4,"titulo":"Hydrothermal treatments applied to agro- and forest-industrial waste to produce high added-value compounds","resumen":"Agro- and forest-industrial wastes are abundant and low cost sources of carbohydrates and phenolic compounds, which can be converted into biofuels, biomaterials, and high added-value compounds by different pathways in small and large biorefineries. The development of technologies based on hydrothermal treatments could improve the utilization of lignocellulosic wastes through the separation of its components (cellulose, hemicellulose, lignin, and extractives) in sequential processes. The adopted technologies for the separation and conversion of these lignocellulosic wastes into synthesis intermediates or products of high added value represent an important part of the total production cost. Low liquid to solid ratios and mild temperatures in the pre-treatment are interesting ways of reducing energy costs, subsequently economizing both steam and electricity. This work focuses on the advantages of using low liquid to solid ratios in the hydrothermal treatment of different agro- and forest-industrial wastes, paying particular attention to the performance of separation, purification, and conversion of hemicelluloses.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238419,"idioma_id":4,"titulo":"The neutrino opacity of neutron rich matter","resumen":"The study of neutron rich matter, present in neutron star, proto-neutron stars and core-collapse supernovae,can lead to further understanding of the behavior of nuclear matter in highly asymmetric nuclei. Heteroge-neous structures are expected to exist in these systems, often referred to as nuclear pasta. We have carriedout a systematic study of neutrino opacity for different thermodynamic conditions in order to assess theimpact that the structure has on it. We studied the dynamics of the neutrino opacity of the heterogeneousmatter at different thermodynamic conditions with semiclassical molecular dynamics model already used tostudy nuclear multifragmentation. For different densities, proton fractions and temperature, we calculatethe very long range opacity and the cluster distribution. The neutrino opacity is of crucial importance forthe evolution of the core-collapse supernovae and the neutrino scattering.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238420,"idioma_id":4,"titulo":"Fragmentation of neutron star matter","resumen":"Background: Neutron stars are astronomical systems with nucleons submitted to extreme conditions. Due tothe long range coulomb repulsion between protons, the system has structural inhomogeneities. These structuralinhomogeneities arise also in expanding systems, where the fragment distribution is highly dependent on thethermodynamical conditions (temperature, proton fraction, . . . ) and the expansion velocity.Purpose: We aim to find the different regimes of fragment distribution, and the existence of infinite clusters.Method: We study the dynamics of the nucleons with a semiclassical molecular dynamics model. Starting withan equilibrium configuration, we expand the system homgeneously until we arrive to an asymptotical configuration(i. e. very low final densities). We study the fragment distribution throughout this expansion.Results: We found the typical regimes of the asymptotical fragment distribution of an expansion: u-shaped,power law and exponential. Another key feature in our calculations is that, since the interaction between protonsis long range repulsive, we do not have always an infinite fragment. We found that, as expected, the faster theexpansion velocity is, the quicker the infinite fragment disappears.Conclusions: We have developed a graph-based tool for the identification of infinite fragments, and found atransition from U-shaped to exponential fragment mass distribution with increasing expansion rate.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238422,"idioma_id":5,"titulo":"Transformaciones en la Política científica y el desarrollo tecnológico","resumen":"El texto recorre las transformacione en la política científica y tecnológica desde fines d ela segunda guerra hasta el presente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238423,"idioma_id":5,"titulo":"Cuerpo y biopoder en los trabajos de Michel Foucault","resumen":"El artículo analiza los conceptos de biopoder, disciplina y biopolítica en los trabajos de Michel Foucault y su vigencia actual.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238424,"idioma_id":5,"titulo":"Gisèle Sapiro. La sociología de la literatura","resumen":"Reseña de Gisèle Sapiro: La sociología de la literatura. Buenos Aires, Fondo de Cultura Económica, 2016. Colección Lengua y Estudios Literarios, 168 páginas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238426,"idioma_id":4,"titulo":"Trypsin and N-aminopeptidase (APN) activities in the hepatopancreas of an intertidal euryhaline crab: Biochemical characteristics and differential modulation by histamine and salinity.","resumen":"No studies are available about biochemical characteristics and modulation (i.e. by endogenous and\/or environmentalcues) of trypsin (a key digestive endoprotease) in hepatopancreas of intertidal euryhaline crabs neitheron the possible concomitant modulation of key ectoproteases such as aminopeptidase-N (APN) involved in&#64257;nal steps of protein digestion. Furthermore, nothing is still known in decapods crustaceans about the role of histamineas primary chemical messenger for modulation of main components of digestive process (i.e. proteases).We determined biochemical characteristics and investigated the effect of histamine injections; of histamine invitro and of acclimation of individuals to lowand high salinity on trypsin and aminopeptidase-N (APN) activitiesin the hepatopancreas of the euryhaline crab Cyrtograpsus angulatus (Dana 1851). Trypsin activity was maximalat pH 7.4 and at 45 °C. APN activity increased frompH 6.6 to 7.6?9.0 and was maintained high at 37?45 °C. Bothactivities exhibited Michaelis-Menten kinetics (apparent Km: trypsin =0.36 mM; APN =0.07 mM). The injectionof 10&#8722;4M histamine decreased trypsin activity (about 40%) in hepatopancreas while did not affect APN activity.Similarly, in vitro 10-4M histamine decreased trypsin activity (about 52%) in hepatopancreas but not APNactivity. Trypsin activity in the hepatopancreas was not affected by acclimation of crabs to low (10 psu) or high(40 psu) environmental salinity while APN activity was increased (about 200%) in 10 psu. The results show thedifferential modulation of trypsin and APN by distinct cues and point to histamine as modulator of intracellulartrypsin by direct action on the hepatopancreas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238430,"idioma_id":4,"titulo":"A Structural Analysis of Topic Ontologies","resumen":"Topic ontologies, Topological analysis, Complex networks',abstract = 'DMOZ is the largest human-edited topic ontology available on the Web. This article studies the structural properties of the DMOZ graph. A number of global and local properties of this graph and the subgraphs resulting from isolating edges of different types are examined by means of metrics commonly used in complex network analysis. In particular, we investigate the presence of various features that characterize small-world networks. This analysis is complemented by examining other characteristics of the graphs such as connectivity and centrality measures. The connectivity and centrality patterns are further studied by means of visualizations of the graphs? k-core decomposition and a selection of strongly connected components. Several non-trivial regularities that are also encountered in other artificial and natural complex networks provide a general picture of this large human-edited topic ontology. This analysis is of major pragmatic interest as it allows a better understanding of notions such as navigability among topics, hierarchical structure and topic cohesiveness, which are of great importance in the design of topic ontologies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238432,"idioma_id":5,"titulo":"Conocimiento experto y autorregulación en adultos mayores jubilados profesionales y no profesionales","resumen":"Si bien se han investigado variables psicosociales implicadas en la adaptación posjubilatoria, existe escaso interés en el factor del conocimiento experto. Este estudio propone comparar las metas de vida a partir del retiro jubilatorio en adultos mayores profesionales y no profesionales, y analizar la relación entre el conocimiento experto y las estrategias de autorregulación, con el fin de contrastar empíricamente el modelo del Grupo de Berlín. Se utilizó un diseño correlacional transversal en una muestra de 258 jubilados distribuidos en dos grupos: profesionales y no profesionales. Se hallaron diferencias en la selección de metas entre ambos grupos y se evidenció que el conocimiento experto se relacionó con un mayor uso de estrategias de optimización y compensación. El grupo no profesional utilizó la estrategia compensación en mayor medida, y el grupo profesional presentó un desempeño significativamente mayor en conocimiento experto. Los datos obtenidos sirven al diseño de programas de asistencia prejubilatoria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238433,"idioma_id":5,"titulo":"La legislación sobre robo en los primeros años del derecho correntino (República Argentina 1825-1832)","resumen":"El proceso de formación del Estado en las provincias argentinas se inició con el surgimiento de las primeras Constituciones escritas, pero la consolidación se dará con la construcción del orden jurídico y las distintas normativas que fijaban las autoridades. El delito de robo ocasionaba en la provincia de Corrientes (Argentina) un grave perjuicio a su economía ya que ésta se basaba en la producción ganadera y rural. Por esa razón el estado estableció una normativa rígida para combatir el robo de ganado y proteger la propiedad rural. Estas pautas legislativas mostraran la evolución jurídica y política del Estado provincial y como el orden constitucional evolucionó paralelamente a la trasformación dela legislación, buscando ambas consolidar un orden jurídico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238437,"idioma_id":4,"titulo":"Diversity of true bugs from Iguazú National Park, Argentina","resumen":"We list all taxa identified to species level, belonging to 18 families of Heteroptera: Reduviidae (63 species), Tingidae(9 species), Alydidae (6 species), Coreidae (39 species), Rhopalidae (11 species), Largidae (1 species), Pyrrhocoridae(4 species), Acanthosomatidae (1 species), Pentatomidae (58 species), Scutelleridae (3 species), Berytidae (1 species),Blissidae (5 species), Colobathristidae (2 species), Cymidae (1 species), Ninidae (1 species), Lygaeidae (6 species),Pachygronthidae (1 species), and Rhyparochromidae (13 species). Among the listed species, 13 are new country recordsbelonging to the families Reduviidae, Tingidae, Pentatomidae, Coreidae, and Alydidae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238438,"idioma_id":5,"titulo":"Radios comunitarias desde una perspectiva indígena. La experiencia de la Organización de Comunidades Aborígenes de Nazareno, Salta-Argentina","resumen":"En este trabajo pretendemos mostrar el trabajo realizado durante la elaboración de la tesis de grado ?Queremos que la gente no pueda vivir sin la radio. Procesos de gestión y de construcción de contenidos en una radio comunitaria. El caso de la Organización de Comunidades Aborígenes de Nazareno (OCAN) Salta, 2014-2016?; reflexionando sobre el recorrido por las distintas facetas que tuvo que pasar la organización para la creación de la primera radio comunitaria en el territorio Qullamarka, algunas veces a pulmón y otras con el apoyo y la colaboración por parte de distintos organismos pertenecientes al Estado Nacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238439,"idioma_id":5,"titulo":"Asociación de eventos académicos y estrategias de afrontamiento con la presencia de burnout en estudiantes de medicina","resumen":"Los estudiantes de medicina están expuestos al desarrollo del síndrome de burnout. El engagement, síndrome teóricamente ?opuesto? al burnout,  muestra una influencia positiva en el funcionamiento personal y académico. Se realizó un estudio observacional analítico, de seguimiento de una cohorte para determinar la asociación entre la presencia de burnout y engagement con la percepción de estrés académico y el empleo de estrategias de afrontamiento en estudiantes de medicina de la Práctica Final (PF) de una universidad pública. Se utilizaron cuestionarios para evaluar las variables. Participaron 103 estudiantes. Se realizó un análisis descriptivo e inferencial, con asociación de variables relevantes y comparación entre grupos. El nivel de significación fue 5%. La frecuencia de burnout fue del 40% en la primera y segunda etapa. El engagement tuvo una frecuencia del 10% en la primera etapa y del 7% en la segunda.  Se encontraron asociaciones estadísticamente significativas de ambos síndromes con eventos académicos y estrategias de afrontamiento. Sería necesario incluir dentro de la educación médica  espacios que posibiliten a los estudiantes discutir sobre el estrés académico, así como promover el desarrollo de estrategias que favorezcan el afrontamiento de las diferentes situaciones estresantes que deben atravesar durante su formación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238442,"idioma_id":5,"titulo":"Juan Iturrioz, la veta artística que no termina","resumen":"Saturnino Iturrioz nació en Irun, Gipuzkoa, Euskadi, en 1883. Fue hijo de Antonio Iturrioz Lecuona (1853-1919) y Feliza Arróspide Estomba (1856-1924), y hermano de Juana (1887-1966), María (1897-1977) y Luisa (1900-1983).Irun se ubica en el extremo Este de la provincia de Gipuzkoa, a unos 23 kilómetros de su capital, Donostia-San Sebastián, y en el límite con la frontera de Francia, separada por el río Bidasoa de la localidad de Hendaia. Existen versiones sobre la presencia aquí de fenicios y cartagineses, pero los testimonios arqueológicos revelan en forma fehaciente la presencia romana en el poblado. Hasta el 1200 perteneció al Reino de Navarra, pero luego fue incorporado a Castilla. Se documenta que en 1203, el rey Alfonso VIII otorga la Carta Puebla a Fuenterrabía, de la cual se independiza en 1766 por Real Cédula del rey Carlos III. Su estratégica posición hizo que en muchas oportunidades la ciudad fuera atacada y sus habitantes debieran defenderla, siendo partícipe de muchos combates a lo largo de su historia.El padre de Juan, Saturnino, vino a Argentina a los 18 años, al principiar el siglo XX, y directamente al entonces Territorio Nacional de La Pampa. Más precisamente, a la estancia ?La Delia?, de la cual fue llamado por unos paisanos que trabajaban allí y necesitaban gente para distintas tareas rurales. Entre otras cosas, se criaban animales vacunos para producción de carne y leche, de tal forma que él se desempeñó en la cremería, de la cual fue el encargado. Sin embargo, su verdadero oficio fue el de carpintero y herrero, tal como lo fuera su padre Antonio, así que además de la cremería debía ocuparse en la estancia del cuidado y reparación de la maquinaria y elementos de labranza. Y luego, cuando por razones laborales debía trasladarse a otro pueblo, ponía su taller para sumar otro ingreso a la economía familiar.Después, cuando las líneas férreas se extendían de sur a norte y de este a oeste del país, Saturnino tuvo la oportunidad de trabajar en la construcción de galpones, de tal forma que viajó por distintos pueblos de la región pampeana. En uno de estos viajes conoció a quién sería su esposa: Amalia Bayer Froschauer, y se casaron en 1924.Juan Iturrioz con dos de sus hermanos en Rolón, La PampaJuan Iturrioz con dos de sus hermanos en Rolón, La Pampa.Amalia nació el 29 de diciembre de 1896 en Kamenka, una comunidad de alemanes del Volga situada a unos 700 kilómetros al sur de Moscú. Estos alemanes comenzaron a llegar a esta región de Rusia en 1764, en un plan colonizador de la región emprendido por la zarina Catalina II, quién les otorgó ciertos beneficios y privilegios, como el respeto de su lengua, religión, costumbres, exención del servicio militar, etc. En un siglo muchos se habían convertido en grandes terratenientes y el progreso era constante en sus ciudades. Sin embargo, a fines del siglo XIX se les quitaron muchos de sus privilegios, y comenzó la emigración hacia Estados Unidos, Canadá, Brasil, Chile, Uruguay y Argentina. Quienes se quedaron allí, sufrirían persecución y prisión durante la etapa soviética.Amalia, junto con sus padres ?José Bayer y Ana Froschauer? y hermanas, lograron llegar a Hamburgo, Alemania, y se embarcaron rumbo a Buenos Aires en 1906. Primero vino su padre y se instaló en Coronel Suárez y trabajó en tareas rurales. Luego vinieron su esposa y las tres hijas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238443,"idioma_id":5,"titulo":"Sebastián de Arriortua, alma de roble, sangre de algarrobo","resumen":"Pablo Bernabé De Arriortúa fue hijo de Antonio de Arriortua y Micaela Viña. Nació en un pequeño poblado llamado Ibarruri, en la provincia de Bizkaia, Euskadi, el 11 de junio de 1890, y fue anotado en Muxica, el ayuntamiento más cercano a su pueblo natal. Sus hermanos fueron Petra, María Juana y José.Fue hijo del segundo matrimonio de su padre. Éste, al casarse ya mayor con una mujer a quién le llevaba muchos años, le pidió a su hermano que en caso de fallecer, se casara con quien fuera su esposa para cuidar de sus hijos. Esto finalmente sucedió, entonces Pablo Bernabé fue criado por su hermana mayor, que emigró a México, y a quién recordó durante toda su vida al despedirse en el puerto de Bilbao para no verla nunca más.Ibarruri se ubica a 32 kilómetros al este de Bilbao, en la margen del río Oka, entre montañas que llegan a poco más de 600 metros de altura, y cuenta con una treintena de habitantes. Desde 1965 pertenece a Muxica, y está incluido en el plan comarcal de Gernika-Bermeo, y cuya población asciende al millar y medio aproximadamente. Allí se encuentra la ermita de San Pedro y San Pablo que data del los siglos XV y XVI, y que es uno de los templos más importante de estilo gótico más importante de Bizkaia.En su caserío se dedicaban a tareas rurales, pero en tiempos difíciles se hacía necesario buscar trabajo para ayudar a la familia. Fue así como Pablo Bernabé se dirigió, siendo muy joven, a la ciudad de Eibar, conocida en todo el mundo por sus fábricas de armas y la calidad de su producción. En la ciudad, a unos 30 kilómetros de Ibarruri y ya en la provincia de Gipuzkoa, encontró trabajo. Allí se ganó el sustento entre 1909 y 1910, y siempre guardó gratos recuerdos de esta etapa de su vida.La familia era numerosa y la chacra familiar, a pesar del esfuerzo de todos, apenas alcanzaba para subsistir. A esto había que sumarle que las perspectivas de trabajo no eran buenas, pues en las fábricas se alternaban períodos buenos con malas épocas.Fue así que su espíritu de aventura y las condiciones que se ofrecían en Argentina para los extranjeros a principios del siglo XX, lo conminó a tomar un barco en el puerto de Bilbao y recalar en Buenos Aires.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238447,"idioma_id":4,"titulo":"Ecomorphological Diversity in the Patagonian Assemblage of Bats from Argentina","resumen":"Patagonian bats are represented by only insectivorous species, five vespertilionids and one molossid species. They constitute an interesting assemblage of temperate species that remains poorly studied. Here we uncover ecomorphological patterns of Patagonian bats using craniodental morphology, aerodynamic measurements, and external bodily characters. Multivariate analysis was applied to characterize morphometric variation of each dataset separately and in combination. We explored the segregation of species in morphospace, and the importance of phylogeny in the assemblage organization. We used a phylogenetic comparative method to evaluate historical effects on the morphofunctional structure. Our results indicated that the species of the Patagonian assemblage segregate in dimensions of morphospace by size and morphology, which would be related to prey selection (trophic differences) and habitat use (different styles of flight). We also demonstrated the impact of different cladogenetic events of the evolutionary history of species on the structuring of the Patagonian assemblage, with the successive addition of non-overlapping, well-defined morphofunctional types imported from other South American regions, and whit speciation events that resulted in species-level endemisms (Myotis chiloensis, Histiotus magellanicus, and Lasiurus varius).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238450,"idioma_id":4,"titulo":"Marine debris ingestion by the South American Fur Seal from the Southwest Atlantic Ocean","resumen":"In this paper, we examined the ingestion of marine debris (MD) in South American fur seals (SAFS), Arctocephalus australis, found dead in coastal beaches of northern Argentina and southern Brazil. Seven percent of 133 SAFS analyzed presented marine debris in their stomach (n = 10), with no differences between sampling countries (Brazil n = 7, Argentina n = 3) and sexes (female = 3; male = 6). However, significant differences were observed between ages classes, with MD exclusively present in stomach contents of young specimens. Plastics represents 90% of MD ingested by the SAFS, whereas regarding the source, fishery-related items (e.g. monofilament lines) were the main MD (70%), with a lesser proportion of packaging (e.g. pieces of bags). Low numbers but large size pieces of MD were found in each stomach affected. Negative effects on the individuals could not be fully evaluated. Therefore, the potential impacts of the marine debris to the SAFS deserve further elucidation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238463,"idioma_id":4,"titulo":"Southern Annular Mode drives multicentury wildfire activity in southern South America","resumen":"The Southern Annular Mode (SAM) is the main driver of climatevariability at mid to high latitudes in the Southern Hemisphere,affecting wildfire activity, which in turn pollutes the air and contributesto human health problems and mortality, and potentiallyprovides strong feedback to the climate system through emissionsand land cover changes. Here we report the largest Southern Hemispherenetwork of annually resolved tree ring fire histories, consistingof 1,767 fire-scarred trees from 97 sites (from 22 °S to 54 °S) in southernSouth America (SAS), to quantify the coupling of SAM and regionalwildfire variability using recently created multicentury proxyindices of SAM for the years 1531?2010 AD. We show that at interannualtime scales, as well as at multidecadal time scales across 37?54 °S,latitudinal gradient elevated wildfire activity is synchronous with positivephases of the SAM over the years 1665?1995. Positive phases ofthe SAM are associated primarily with warm conditions in thesebiomass-rich forests, in which widespread fire activity depends on fueldesiccation. Climate modeling studies indicate that greenhouse gaseswill force SAM into its positive phase even if stratospheric ozonereturns to normal levels, so that climate conditions conducive to widespreadfire activity in SAS will continue throughout the 21st century.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238464,"idioma_id":4,"titulo":"Risk Prediction Based on Time and GPS Patterns","resumen":"Traffic produces not only pollution but also many incidents resulting inmaterial lost and human injuries or even persons dead. But not all the incidents involve two cars, it may be pedestrian and any type of cycles (motorcycles, bicycles, tricycles, etc.). Most of the approaches try to model traffic accidents using traditional information and avoiding others, such as environmental elements, driver profile, weather, regulations, eventual circumstances like strikes with roadblocks, street reparations, railroads crossings, etc. This paper presents a model for risk prediction, and the impact of varying geographical information details on the precision of the underlying Inference System (a Soft Computing model with a ruled Expert System and a Harmonic System focused on time patterns of events). Its flexibility and robustness has a price: certainly minimal to apriori knowledge. This work outlines the working model implemented as a prototype named KRONOS, and a statistical evaluation of its sensibility to dynamic GPS information. Trafficrisk requires this type of flexible and adaptive model due to the high number of alternatives to consider. The model would also be improved by adding certain specific Fuzzy Logic for pattern management during the matching process. The model would also be improved by adding certain specific Fuzzy Logic for pattern management during the matching process.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238466,"idioma_id":4,"titulo":"Assessment of seasonal soil moisture forecasts over Southern South America with emphasis on dry and wet events","resumen":"The importance of forecasting extreme wet and dry conditions from weeks to months in advance relies on the need to prevent considerable socio-economic losses, mainly in regions of large populations and where agriculture is a key value for the economies, such as Southern South America (SSA). To improve the understanding of the performance and uncertainties of seasonal soil moisture and precipitation forecasts over SSA, this study aims to: 1) perform a general assessment of the Climate Forecast System version-2 (CFSv2) soil moisture and precipitation forecasts against observations and soil moisture simulations based on GLDAS-2.0; 2) evaluate the CFSv2?s ability to represent wet and dry events through forecasted Standardized Precipitation Index (SPI) and the Standardized Soil Moisture Anomalies (SSMA); and 3) analyze the capability of a statistical methodology (merging observations and forecasts) in representing a severe drought event.Results show that both SPI and SSMA forecast skill is regionally and seasonally dependent. In general a fast degradation of the forecasts skill is observed as the lead time increases, resulting in almost no added value with regard to climatology at lead times longer than 3 months. Additionally, a better performance of the SSMA forecasts is observed compared to the SPI3, with a higher skill for dry events against wet events. The CFSv2 forecasts are able to represent the spatial patterns of the 2008-2009 severe drought event, although it shows crucial limitations regarding to the identification of drought onset, duration, severity and demise, considering both meteorological (SPI) and agricultural (SSMA) drought conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238467,"idioma_id":4,"titulo":"Corynespora cassiicola and Stemphylium lycopersici infection and disease development on tomatoes in Argentina","resumen":"Two pathogens were isolated from tomatoes with severe chlorosis and necrosis in northwestern Argentina. Monosporic cultures were morphologically characterisedand molecularly identified as Stemphylium lycopersici and Corynespora cassiicola. This is the first report of C. cassiicola infecting tomato in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238469,"idioma_id":4,"titulo":"Early ciliary and prominin-1 dysfunctions precede neurogenesis impairment in a mouse model of type 2 diabetes","resumen":"Diabetes mellitus (DM) is reaching epidemic conditions worldwide and increases the risk for cognition impairment and dementia. Here, we postulated that progenitors in adult neurogenic niches might be particularly vulnerable. Therefore, we evaluated the different components of the mouse subventricular zone (SVZ) during the first week after chemical induction of type 1 and type 2 diabetes-like (T1DM and T2DM) conditions. Surprisingly, only T2DM mice showed SVZ damage. The initial lesions were localized to ependymal cilia, which appeared disorientated and clumped together. In addition, they showed delocalization of the ciliary membrane protein prominin-1. Impairment of neuroprogenitor proliferation, neurogenic marker abnormalities and ectopic migration of neuroblasts were found at a later stage. To our knowledge, our data describe for the first time such an early impact of T2DM on the SVZ. This is consistent with clinical data indicating that brain damage in T2DM patients differs from that in T1DM patients.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238474,"idioma_id":4,"titulo":"Corynespora cassiicola and Stemphylium lycopersici infection and disease development on tomatoes in Argentina","resumen":"Two pathogens were isolated from tomatoes with severe chlorosis and necrosis in northwestern Argentina. Monosporic cultures were morphologically characterised and molecularly identified as Stemphylium lycopersici and Corynespora cassiicola. This is the first report of C. cassiicola infecting tomato in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238477,"idioma_id":4,"titulo":"Human renal adipose tissue induces the invasion and progression of renal cell carcinoma","resumen":"We evaluated the effects of conditioned media (CMs) of human adipose tissuefrom renal cell carcinoma located near the tumor (hRATnT) or farther away fromthe tumor (hRATfT), on proliferation, adhesion and migration of tumor (786-O andACHN) and non-tumor (HK-2) human renal epithelial cell lines. Human adipose tissues were obtained from patients with renal cell carcinoma (RCC) and CMs from hRATnT and hRATfT incubation. Proliferation, adhesion and migration were quantified in 786-O, ACHN and HK-2 cell lines incubated with hRATnT-, hRATfT- or control-CMs. We evaluated versican, adiponectin and leptin expression in CMs from hRATnT and hRATfT. We evaluated AdipoR1\/2, ObR, pERK, pAkt y pPI3K expression on cell lines incubated with CMs. No differences in proliferation of cell lines was found after 24 h of treatment with CMs. All cell lines showed a significant decrease in cell adhesion and increase in cell migration after incubation with hRATnT-CMs vs. hRATfT- or control-CMs. hRATnT-CMs showed increased levels of versican and leptin, compared to hRATfT-CMs. AdipoR2 in 786-O and ACHN cells decreased significantly after incubation with hRATfT- and hRATnT-CMs vs. control-CMs. We observed a decrease in the expression of pAkt in HK-2, 786-O and ACHN incubated with hRATnT-CMs. This result could partially explain the observed changes in migration and cell adhesion. We conclude that hRATnT released factors, such as leptin and versican, could enhance the invasive potential of renal epithelial cell lines and could modulate the progression of the disease","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238479,"idioma_id":4,"titulo":"Magnetic nanoparticles for drug targeting: from design to insights into their systematic toxicity. Preclinical evaluation of hematological, vascular and neurobehavioral toxicology","resumen":"A simple two-step drug encapsulation method was developed to obtain biocompatible magnetic nanocarriersfor the potential targeted treatment of diverse diseases. The nanodevice consists of a magnetitecore coated with chitosan (Chit@MNPs) as a platform for diclofenac (Dic) loading as a model drug (Dic?Chit@MNPs). Mechanistic and experimental conditions related to drug incorporation and quantificationare further addressed. This multi-disciplinary study aims to elucidate the toxicological impact of the MNPsat hematological, vascular, neurological and behavioral levels. Blood compatibility assays revealed thatMNPs did not affect either erythrosedimentation rates or erythrocyte integrity at the evaluated doses(1, 10 and 100 &#956;g mL&#8722;1). A microscopic evaluation of blood smears indicated that MNPs did not inducemorphological changes in blood cells. Platelet aggregation was not affected by MNPs either and just aslight diminution was observed with Dic?Chit@MNPs, an effect possibly due to diclofenac. The examinedformulations did not exert cytotoxicity on rat aortic endothelial cells and no changes in cell viability ortheir capacity to synthesize NO were observed. Behavioral and functional nervous system parameters in afunctional observational battery were assessed after a subacute treatment of mice with Chit@MNPs. Theurine pools of the exposed group were decreased. Nephritis and an increased number of megakaryocytesin the spleen were observed in the histopathological studies. Sub-acute exposure to Chit@MNPs did notproduce significant changes in the parameters used to evaluate neurobehavioral toxicity. The aspectsfocused on within this manuscript are relevant at the pre-clinical level providing new and novel knowledgeconcerning the biocompatibility of magnetic nanodevices for biomedical applications.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238480,"idioma_id":4,"titulo":"Mild microwave-assisted synthesis of aluminum-pillared bentonites: thermal behavior and potential applications","resumen":"Two types of bentonites were modified using a cleaner method to prepare aluminum-pillared clays. This methodology involved a purifying stage, an intercalation process, and a microwave irradiation step at low energy power. Structural changes induced by pillaring process were demonstrated by thermal behavior, as well as morphological characterization. The effect of pillaring process on thermal stability of clays was studied, and the mass lost associated with the dehydroxylation of the octahedral clay sheets was not detected for modified bentonites. In addition, an analysis of their chemical composition and crystalline structure was also performed. Concerning industrial applications of these bentonites, two potential uses were proposed: (1) as reinforcement of different polymers matrices such as thermoplastic starch (TPS), high-density polyethylene (HDPE), and poly (styrene-b-butadiene-b-styrene), SBS; and (2) as removal agent for cadmium (Cd) species present in wastewaters. Bentonite particles reinforced thermoplastic starch matrix and increased ultraviolet barrier capacity of HDPE composites. Besides, bentonites improved the mechanical performance and modified barrier properties of SBS. Regarding effluents purification, an adequate Cd adsorption from aqueous solutions was observed (77%), proving their feasibility to be used as non-conventional removal agents.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238482,"idioma_id":4,"titulo":"Magnetic iron oxide nanoparticles as novel and efficient tools for atherosclerosis diagnosis","resumen":"Cardiovascular complications derivate from atherosclerosis are the main cause of death in western world. An early detection of vulnerable atherosclerotic plaques is primordial for a better care of patients suffering the pathology. In this context nanotechnology has emerged as a promising tool to achieve this goal. Nanoparticles based on magnetic iron oxide (MNPs) have been extensively studied for their use in cardiovascular disease diagnosis, as well as in other pathologies. The present review aims to describe and analyze the most current literature regarding to this topic, offering the level of detail required to reproduce the experimental tasks providing a critical input of the latest available reports. The current diagnostic features are presented and compared, highlighting their advantages and disadvantages. Information on novel technology intended to this purpose is also recompiled and in deep analyzed. Special emphasis is placed in magnetic nanotechnology, remarking the possibility to assess selective and multifunctional systems to the early detection of artherosclerotic pathologies.Finally, in view of the state of the art, the future perspectives about the trends on MNPs in artherosclerorsis diagnostic and treatment have also been adressed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238484,"idioma_id":5,"titulo":"Entre lo queer y lo cuir: arte, política y críticas pedagógicas en Argentina","resumen":"La territorialización argentina de la perspectiva queer articuló la academia con los movimientos sociales, TLGB y de derechos humanos. Potenciándose con las políticas trans\/travestis contra la represión policial e institucional, la crítica queer visibilizó la jerarquización producida por las diferencias sexo-genéricas a través de los mapas sociales trazados por las estratificaciones de clase, etnia y edad de los cuerpos. La ley que amplió el matrimonio con independencia del sexo de sus contrayentes (2010) y la Ley de Identidad de Género (2012), entre otras, desafían e impactan la implementación institucional de la Educación Sexual Integral frente a la tensión entre la normalización identitaria de las diferencias y el sistemático cuestionamiento y desmontaje de los dispositivos de (a)normalización. Este trabajo propone una genealogía política de las primeras territorializaciones de la perspectiva queer en Argentina para reflexionar sobre la articulación de los activismos y los movimientos sociales con los dispositivos institucionales de producción, legitimación y circulación de conocimientos y saberes en clave sexo-genérica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238485,"idioma_id":5,"titulo":"Enografía crítica y crítica etnográfica: hacia una pedagogía crítica y una crítica pedagógica para la historización de la educación sexual en Argentina","resumen":"Este ensayo problematiza, desde una perspectiva epistemológica y metodológica, el ?realismo científico?, focalizando el énfasis investigativo puesto en la sexualidad para interpelar su carácter mitológico. Así, se busca cuestionar la economía narrativa de su conceptualización basada en la naturalización de la genitalidad como dato inapelable para pautar el sexo y el género como correspondencias legítimas entre cuerpo y subjetividad. Desde esta perspectiva, propone una reflexión sobre la forma ?ensayo? para presentarla como dispositivo etnográfico e historiográfico clave en pos del abordaje de la ritualización clínica del sistema sexo-género en su institucionalización pedagógica. El objetivo de este enfoque es abonar la indagación sobre las regulaciones pedagógicas y educativas de los protocolos de enseñanza y aprendizaje de las identidades y las diferencias sexo-genéricas a partir del relevamiento de líneas epistemológicas críticas para historizar la educación sexual.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238486,"idioma_id":5,"titulo":"El sacrificio público de las diferencias: universalización de lo viril y ritualización del bullying en la construcción de la ciudadanía moderna","resumen":"Este trabajo visibiliza la tríada etnográfica sacrificio-mito-ritual como herramienta crítica para analizar el vínculo institucional entre el sacrificio público de las diferencias en la construcción social de las identidades de género y la trama relacional que se popularizó como bullying en la sociabilidad occidental regida por la referencia al universal: el Sujeto viril. Desde esta perspectiva, se ofrece una genealogía para focalizar la matriz cultural del racismo de Estado que se replica y resignifica no sólo con la diferenciación étnica sino también con otras tecnologías de estratificación como los dispositivos de sexua(liza)ción que fortalecen el dominio masculino y la inferiorización de lo femenino. Finalmente, se subraya cómo la universalidad sobre la que se plantea el estatuto hetero-patriarcal de lo masculino basa su legitimidad en una pedagogía del deseo para la que la ritualidad conceptualizada como bullying es un enclave fundamental de reproducción social.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238487,"idioma_id":5,"titulo":"Derecho a pensión y uniones convivenciales. Una mirada renovada a propósito de la puesta en vigencia del Código Civil y Comercial de la Nación","resumen":"Análisis del&nbsp; art. 53 de la ley Nacional del Sistema Integrado de Jubilaciones y Pensionesnº 24.241 a l a luz de las nuevas previsiones normativas contenidas en el&nbsp;&nbsp; libro segundo'Relaciones de Familia' del Código Civil y Comercial de la Nación.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238489,"idioma_id":4,"titulo":"Medicinal Plant Diversity and Inter-Cultural Interactions between Indigenous Guarani, Criollos and Polish Migrants in the Subtropics of Argentina.","resumen":"Numerous studies highlight the importance of phytotherapy for indigenous and non-indigenous people in different parts of the world. In this work we analyze the richness (number of species), diversity (plant identity and the number of illnesses for which it is used) and similarity of plant species and illnesses treated with them, in order to contribute new data and insight into the importance of plant medicines to the local medical systems of people living inMisiones province, in the subtropics of Argentina. Three sympatric groups were compared: Guarani Indians, Criollos (mestizos) and Polish migrants. Quantitative scrutiny was focused on both primary and secondary sources. The similarity and diversity of medicinal plants and uses between groups was calculated by applying the Sørensen quantitative coefficient and the Shannon-Wiener index, respectively. In order to identify the characteristic plant speciesused by each group, the Cultural Importance and Prevalence Value (CIPV) was calculated based on the species Indicator Value (IndVal), which combines a species relative abundance with its relative frequency of occurrence in the various groups, and modified according to the type of the analyzed data. The important finding is a great variation in the number of species used by the study groups. Altogether, 509 botanical species were registered: Guarani (397), Criollos (243) and Polish migrants (137). For all groups, the use of nativemedicinal plants prevailed. The Guarani appear to be the local experts in use of medicinal plants. There is the significant difference in the number of treated illnesses by each taxon among three groups. Criollos and Polish migrants exhibit the greatest similarity in illnesses treated with medicinal plants. These groups share a corpus of knowledge related to illness nosology, and have a symptomatic approach to illness treatment. The Guarani have an etiological approach to illness diagnosis and healing, which may be viewed as a barrier to theexchange of knowledge about home medicine with other ethnic groups of Misiones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238491,"idioma_id":4,"titulo":"Histological changes in lung tissues related with sub-chronic exposure to ambient urban levels of PM 2.5 in C&oacute;rdoba, Argentina","resumen":"Concentration of fine particulate matter (PM2.5) is one of the most important environmental parameters to estimate health impacts attributable to air pollution. Despite the fact there are many studies regarding PM2.5 effects on human health, most of them were performed under conditions that do not simulate the natural particles interaction with the organism. In the present paper, we studied the effects of mammals? sub-chronic exposure to PM2.5 on the lower respiratory tract, addressing realistic exposure conditions to normal urban air. Thus, we exposed Wistar rats under controlled settings to the same normal urban air, with and without particles. Next, we analyzed chemical composition of PM2.5 and lungs samples, performed a histologic examination and run the comet assayto assess genotoxic effects. We found a strong agreement between lung tissues and PM2.5 elemental composition suggesting that metals found in lungs came from the particles inhaled. Histological analysis showed a mild to moderate infiltration, with a reduction of alveoli lumen and increment of alveolar macrophages and periodic acid-Schiff (PAS) (+) cells in treated animals. We also observed an increase in the number of nuclei with comets, mostly comets type 3, with a high DNA fragmentation as well. These results provide strong evidence that sub-chronic exposure to low particle levels, even below the 24 h WHO standard, can cause injuries in lungs tissues and DNA damage, as well.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238492,"idioma_id":4,"titulo":"Discovering knowledge from data clustering using automatically defined interval type-2 fuzzy predicates","resumen":"In data clustering fuzzy predicates act as cluster descriptors providing linguistically expressed knowledge which indicates how features are related to each cluster. Fuzzy predicates directly and automatically ob- tained from data enable discovering knowledge inside clusters, even when there is no prior-information about the clustering problem. In this work a new method for automatic discovering of interval type-2 fuzzy predicates in data clustering is proposed, called Type-2 Data-based Fuzzy Predicate Clustering (T2- DFPC). In a first stage, a data analysis is performed by making a random partition of the original data and running a clustering scheme that automatically determines the suitable number of clusters. From this stage, interval type-2 fuzzy predicates are discovered. Results obtained on very different cluster- ing datasets show that the T2-DFPC method was consistently one of the best in terms of accuracy. The method preserves all known advantages of the interval type-2 FL to deal with problems with vagueness, quantifying the degree of truth of the fuzzy predicates and modelling the variability of the data inside the clusters. The proposed method is a fast, useful, general, and unsupervised approach for interpretable data clustering, being the knowledge-extracting capabilities one of the main contributions. Linguistic ex- pressions can be easily adapted to match the terminology used in the field the data are related to. The predicates are able to generalize the knowledge for new cases (new data), as an intelligent system. This new approach might be surprisingly useful in contexts where, besides the clustering partition, summary information from data is of interest.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238494,"idioma_id":4,"titulo":"TP73 DNA methylation and Upregulation of deltaNp73 are associated with an adverse prognosis in breast cancer","resumen":"Aim Accumulated evidence supports the fact that aberrant methylation of TP73 gene and increased levels of &#916;Np73 in primary tumors have been shown to correlate with poor prognosis. However, little is known regarding the transcriptional and functional regulation of the TP73 gene in breast cancer. The aim of the present study was to determine the expression of &#916;Np73 isoform, its relation to DNA methylation of TP73 and their clinical prognostic significance in breast cancer patients.Methods The TP73 gene methylation was studied in TCGA datasets and in 70 invasive ductal breast carcinomas (IDC). The expression of p73 isoforms was evaluated by immunohistochemistry and western blot and it was correlated with clinicopathological variables and clinical outcome.Results We observed that the methylation of diverse CpG islands of TP73 differed significantly between molecular subtypes. Inverse correlation was found between p73 protein expression and the methylation status of TP73 gene. The expression of exon 3?of p73 (only expressed in &#916;Np73), was significantly higher in patients with wild-type p53. Immunohistochemistry analysis revealed that all p73 isoforms were localized in both the nuclear and cytoplasmic compartment. We confirmed towards a positive association between expression of &#8710;Np73 and high histological grade. Conclusions Our findings suggest that high expression of &#916;Np73 could be used to determine the aggressiveness of IDCs and could be incorporated in the pathologist´s report.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238495,"idioma_id":4,"titulo":"Particleboard Based on Rice Husk: Effect of Binder Content and Processing Conditions","resumen":"In the development of materials based on renewable resources, the search for lignocellulosic substitutes for wood is one of the biggest challenges that academia and the particleboard and wood industries are facing. In this article, particleboards were processed using rice husk, an agricultural waste, as a substitute for wood. Rice husk without any further treatment was processed into particleboards using phenol-formaldehyde resin as binder. The effect of the processing parameters, pressure and binder content (BC) on the density, water absorption (WA), thickness swelling (TS), modulus of rupture (MOR) and modulus of elasticity (MOE) was analyzed. The performance of the obtained panels was evaluated in comparison with the US Standard ANSI\/A208.1. Particleboards with 11% of BC met the minimum requirements of MOR and MOE recommended by the ANSI specifications for commercial use, while particleboards with high BC (14%) also accomplished the requirements for industrial use, finding a resourceful use for this agricultural waste.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238496,"idioma_id":4,"titulo":"Long-term stability of compression-molded soybean protein concentrate films stored under specific conditions","resumen":"Post-processing evolution of the functional properties of soybean protein concentrate(SPC) films, plasticized with varying levels of glycerol and processed by compressionmolding, was examined over a period of 90 days. Films stored in the glassy state(25±2ºC and 65±2% relative humidity) lost glycerol and water over time, as determinedby gas chromatography and the decline in moisture content. SPC films plasticized with40-50% glycerol showed a time-dependent increment of the elastic modulus and thetensile strength. In turn, the elongation, barrier properties, soluble mass and opacity ofthese films varied marginally with time. By contrast, films with 30% glycerol lost themost moisture and their elongation was reduced significantly, while water vaporpermeability slightly increased with aging. The performance of aged films resulted fromthe balance between plasticizer and water loss, and the progressive replacement ofunordered structures by intermolecular hydrogen bonded b-sheets and aggregates.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238497,"idioma_id":4,"titulo":"Age and growth of Franciscana dolphins from northern Argentina","resumen":"Knowledge of growth patterns of an animal species is fundamental to understand their life history. This information is alsoused to help define population boundaries of threatened cetaceans, such as the Franciscana dolphin, Pontoporia blainvillei.A total of 108 Franciscana dolphins incidentally captured in artisanal fishing nets in estuarine and marine coastal waters ofthe northern part of the Franciscana Management Area IV (North FMA IV), Argentina, were studied. The objective of thepresent paper was to study age and growth parameters of Franciscanas from North FMA IV and to compare these parametersbetween estuarine and marine potential populations within this area. We used von Bertalanffy and Gompertz growth curvesto model growth trajectories. The estimated asymptotic lengths demonstrated that Franciscana dolphins from this area weresmaller (females: 136.3 cm and males, 122.1 cm) than southern FMA IV values previously published. They also showedthe reverse sexual size dimorphism that is known across their range. However, the estimated asymptotic length was not statisticallydifferent between the estuarine and marine females within the study area. In spite of this, the fact that the northernforms of the FMA IV were smaller than the southern specimens supports the hypothesis of more than one population of thespecies within this management area. The North FMA IV has the highest reported mortality levels of Franciscana dolphinswithin the FMA IV, these results are relevant to the knowledge base of Franciscana dolphins in the region.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238499,"idioma_id":5,"titulo":"Capacidad de supervivencia de Corynebacterium pseudotuberculosis biovar ovis en distintos suelos de la provincia de Chubut, Patagonia argentina","resumen":"Corynebacterium pseudotuberculosis se transmite entre ovinos de la Patagoniaargentina y ocasiona pseudotuberculosis. Esta bacteria, que infecta ganglios superficiales y vísceras, ingresa al animal a través de heridas en la piel o membranas mucosas. Durante la esquila, se cortan abscesos superficiales que drenan el contenido purulento y contaminan las herramientas y el suelo. El objetivo de este trabajo fue evaluar la capacidad de C. pseudotuberculosisde sobrevivir a lo largo del tiempo en suelos de la Patagonia extraandina. Se recolectaron 5muestras de suelos de distintas zonas de la provincia del Chubut (Patagonia extraandina) con características fisicoquímicas diferenciales en lo que respecta a contenido de materia orgánica,pH, conductividad eléctrica y textura. Diferentes alícuotas de estas muestras se inocularon conla cepa de C. pseudotuberculosis PAT10, aislada de un ovino patagónico, y se conservaron a temperatura ambiente. A distintos tiempos se determinó el número de bacterias supervivientes. El 60% de la población de C. pseudotuberculosis inoculada sobrevivió durante 80 y 210 días en suelos con moderadas y altas concentraciones de materia orgánica, respectivamente. Los suelos decaracterísticas diversas de la Patagonia contaminados con poblaciones de C. pseudotuberculosis cumplirían un papel importante en el ciclo de infección en la naturaleza. La supervivencia de la bacteria por largos períodos se vio favorecida por el mayor contenido de materia orgánica sumado a la textura franco-limosa y no se observó la influencia de variables como el pH y lasalinidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238500,"idioma_id":4,"titulo":"Association patterns and population dynamics of bottlenose dolphins in the Strait of Sicily (Central Mediterranean Sea): implication for management","resumen":"An understanding of the population dynamicsand social organization of cetaceans is essential to managethe influence of anthropogenic activities. In this study, thepopulation size, site fidelity and social interactions ofbottlenose dolphins in the Strait of Sicily (Italy) wereinvestigated to provide recommendations for their conservation.Mark-recapture analysis was based on the encounterhistories of 103 marked dolphins from 2004 to 2015.The POPAN formulation of the Jolly?Seber model inMARK software was used to estimate the size of the superpopulation.Site fidelity and social organization were estimatedfor individuals re-sighted C3 times. The estimatedpopulation size was 140 (SE = 15.75; 95%CI = 106?164). Dolphins had low site fidelity, and bothadults and sub-adults move outside the study area. Femaleswith calves used the area longer than other individuals.Based on our results, dolphins? home range likely extendedbeyond the study area. The mean value of the Half-WeightAssociation Index was low and the preferred associationwas by casual acquaintance. However, we found a distinctaggregation of post-parturition females during the final2 years of the study. Therefore, the pattern of associationwas apparently a response to an ecological requirement,which was the possibility to breed in high productivitywaters. Whether these individuals are part of a large","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238501,"idioma_id":4,"titulo":"Fuzzy Control of a Germination Chamber","resumen":"The design of a fuzzy control system for a germination chamber for hydroponic crops is presented. The system measures humidity and temperature inside the chamber and, by means of a Sugeno type fuzzy controller embedded in an Arduino board, it generates control signals that are sent to a forced ventilation system and to the artificial lighting control system. Experiences were carried out with a germination chamber using this fuzzy control system. Lettuce seeds were sowed in the fuzzy control chamber and on a conventional culture tray, with the former yielding better growth results.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238502,"idioma_id":5,"titulo":"ANÁLISIS DIAGNÓSTICO DEL ESTADO DE SITUACIÓN SOCIOPRODUCTIVO DEL PARTIDO DE LOMAS DE ZAMORA Y SU ÁMBITO DE INFLUENCIA","resumen":"Este artículo exhibe el resultado del trabajo realizado por investigadores de la Facultad de Ingeniería de Lomas de Zamora en el marco del Proyecto 'Análisis diagnóstico del estado de situación socio productivo del Partido de Lomas de Zamora y su ámbito de influencia?. Se buscó contar con un diagnóstico de la situación socioeconómica y caracterización de la estructura productiva de la región a partir de una exhaustiva búsqueda y revisión de información secundaria que permitiese dar luz acerca de algunos aspectos relacionados a la situación actual y posicionamiento relativo de la zona bajo análisis y, al mismo tiempo, identificar qué debilidades informativas existen y qué tipo de estudios futuros sería deseable realizar. Se analiza y reflexiona sobre la evolución reciente del municipio, su ámbito de influencia y su situación actual para identificar dónde están las necesidades de información y posibles ejercicios u operativos de relevamiento que se podrían hacer, preferentemente con la colaboración\/participación del gobierno provincial, municipal y la UNLZ, a fin de mejorar el conocimiento territorial e informar y orientar políticas públicas a futuro.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238507,"idioma_id":5,"titulo":"El intelectual en el kiosco de revistas: Ciudad (1955-56)","resumen":"Redactada por un conjunto ecle&#769;ctico de jo&#769;venes intelectuales unidos en su deseo de actuar, de Adolfo Prieto a Jose&#769; Alfredo Marti&#769;nez de Hoz, Ciudad intento&#769; ser a la vez una plataforma y una &#8213;tentativa de diagno&#769;stico&#8214; para la accio&#769;n. Ese pragmatismo le brinda inesperadas posibilidades epistemolo&#769;gicas, acaso vedadas a la superioridad moral de Sur o al voluntarismo de Contorno, las publicaciones que ha preferido la cri&#769;tica para describir la imaginacio&#769;n cri&#769;tica de la de&#769;cada. El intelectual que imagina Ciudad ya no actu&#769;a desde el Estado ni espera la panacea de la institucio&#769;n escolar; esta&#769; obligado entonces a preguntarse por la situacio&#769;n de la lectura en el contexto de la cultura de masas, y a considerar la expansio&#769;n y la heterogeneidad del kiosco de revistas a la vez como objeto de estudio y como el espacio de intervencio&#769;n ma&#769;s pu&#769;blico al que tendra&#769; acceso, al menos mientras el peronismo continu&#769;e en el poder.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238508,"idioma_id":4,"titulo":"Development and Validation of a Computational Model Ensemble for the Early Detection of BCRP\/ABCG2 Substrates during the Drug Design Stage","resumen":"Breast Cancer Resistance Protein (BCRP) is an ATP-dependent efflux transporter linked to the multidrug resistance phenomenon in many diseases such as epilepsy and cancer and a potential source of drug interactions. For these reasons, the early identification of substrates and nonsubstrates of this transporter during the drug discovery stage is of great interest. We have developed a computational nonlinear model ensemble based on conformational independent molecular descriptors using a combined strategy of genetic algorithms, J48 decision tree classifiers, and data fusion. The best model ensemble consists in averaging the ranking of the 12 decision trees that showed the best performance on the training set, which also demonstrated a good performance for the test set. It was experimentally validated using the ex vivo everted rat intestinal sac model. Five anticonvulsant drugs classified as nonsubstrates for BRCP by the model ensemble were experimentally evaluated, and none of them proved to be a BCRP substrate under the experimental conditions used, thus confirming the predictive ability of the model ensemble. The model ensemble reported here is a potentially valuable tool to be used as an in silico ADME filter in computer-aided drug discovery campaigns intended to overcome BCRP-mediated multidrug resistance issues and to prevent drug-drug interactions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238509,"idioma_id":4,"titulo":"Induction of ABCG2\/BCRP restricts the distribution of zidovudine to the fetal brain in rats","resumen":"Safety concerns for fetus development of zidovudine (AZT) administration as prophylaxis of vertical transmission of HIV persist. We evaluated the participation of the ATP-binding cassette efflux transporter ABCG2 in the penetration of AZT into the fetal brain and the relevance for drug safety. Oral daily doses of AZT (60&nbsp;mg\/kg body weight) or its vehicle were administered between post gestational days 11 (E11) and 20 (E20) to Sprague-Dawley pregnant rats. At E21, animals received an intravenous bolus of 60&nbsp;mg AZT\/kg body weight in the presence or absence of the ABCG2 inhibitor gefitinib (20&nbsp;mg\/kg body weight, ip) and AZT in maternal plasma and fetal brain were measured by HPLC-UV. ABCG2 protein expression in placenta and fetal brain, as well as mitochondrial function and ultrastructure in fetal brain were also analyzed. In utero chronic exposure to AZT markedly induced ABCG2 expression in placenta and fetal brain whereas did not significantly alter mitochondrial functionality in the fetal brain. The area-under-the-concentration-time-curve of AZT significantly decreased in fetal brains isolated from AZT-exposed fetuses compared to control group, but this effect was abolished by ABCG2 inhibition. Our results suggest that the absence of mitochondrial toxicity in the fetal brain after chronic in utero administration of AZT could be attributed to its low accumulation in the tissue caused, at least in part, by ABCG2 overexpression. We propose that any interference with ABCG2 activity due to genetic, pathological or iatrogenic factors would increase the amount of AZT reaching the fetal brain, which could increase the risk of toxicity of this drug on the tissue.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238510,"idioma_id":5,"titulo":"MODELADO DE SISTEMAS NANOESTRUCTURADOS COMO CATALIZADORES DE LA REACCIÓN DE LA REDUCCIÓN DE OXIGENO","resumen":"xxx","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238512,"idioma_id":4,"titulo":"First ever report of a bite by Nabis argentinus Meyer-Dür (Hemiptera: Heteroptera: Nabidae) on a human","resumen":"Herein, we described the first ever reported bite of Nabis argentinus Meyer-Dür 1870 on a human. The bite was registered in the locality Santa Rosa La Pampa, Argentina (36°37´29.02'S, 64°17´19.13'W).  The insect was not provoked by the victim, and thus, the bite was probably not in self-defense. We therefore concluded that the insect bite the victim because it was searching for sources of hydration.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238515,"idioma_id":4,"titulo":"Developmental programmes in the evolution of Equisetum reproductive morphology: a hierarchical modularity hypothesis","resumen":"Background The origin of the Equisetum strobilus has long been debated and the fossil record has played an important role in these discussions. The paradigm underlying these debates has been the perspective of the shoot as node?internode alternation, with sporangiophores attached at nodes. However, fossils historically excluded from these discussions (e.g. Cruciaetheca and Peltotheca) exhibit reproductive morphologies that suggest attachment of sporangiophores along internodes, challenging traditional views. This has rekindled discussions around the evolution of the Equisetum strobilus, but lack of mechanistic explanations has led discussions to a stalemate.Scope A shift of focus from the node?internode view to a perspective emphasizing the phytomer as a modular unit of the shoot, frees the debate of homology constraints on the nature of the sporangiophore and inspires a mechanism-based hypothesis for the evolution of the strobilus. The hypothesis, drawing on data from developmental anatomy, regulatory mechanisms and the fossil record, rests on two tenets: (1) the equisetalean shoot grows by combined activity of the apical meristem, laying down the phytomer pattern, and intercalary meristems responsible for internode elongation; and (2) activation of reproductive growth programmes in the intercalary meristem produces sporangiophore whorls along internodes.Conclusions Hierarchical expression of regulatory modules responsible for (1) transition to reproductive growth; (2) determinacy of apical growth; and (3) node?internode differentiation within phytomers, can explain reproductive morphologies illustrated by Cruciaetheca (module 1 only), Peltotheca (modules 1 and 2) and Equisetum (all three modules). This model has implications ? testable by studies of the fossil record, phylogeny and development ? for directionality in the evolution of reproductive morphology (Cruciaetheca?Peltotheca?Equisetum) and for the homology of the Equisetum stobilus. Furthermore, this model implies that sporangiophore development is independent of node?internode identity, suggesting that the sporangiophore represents the expression of an ancestral euphyllophyte developmental module that pre-dates the evolution of leaves.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238517,"idioma_id":4,"titulo":"A new cheirolepidiaceae (Coniferales) from the early jurassic of patagonia (argentina): Reconciling the records of impression and permineralized fossils","resumen":"PREMISE OF THE STUDY: Plants preserved in different fossil modes provide complementary data concerning the paleobiology and evolutionary relationships among plant groups. New material from the Early Jurassic of Patagonia shows the importance of combining these sources of information, as we describe the first compression\/impression fossils of Pararaucaria, a genus of the extinct conifer family Cheirolepidiaceae previously known from permineralized fossils. These fossils extend the temporal range of this genus and may allow its wider recognition in the fossil record. METHODS: We studied fossil plants from the Early Jurassic (Pleinsbachian-Toarcian) locality of Taquetrén in Patagonia, Argentina using standard paleobo-tanical preparation and description techniques. KEY RESULTS: Pararaucaria taquetrensis consists of isolated ovuliferous scales and small seed cones with helically arranged bract-scale complexes attached to scale-leaf foliage. Bract-scale complexes consist of separated bracts and ovuliferous scales with two seeds and three broad distal lobes. CONCLUSIONS: Pararaucaria taquetrensis represents the oldest known Cheirolepidiaceae seed cones from the Southern Hemisphere, and this material highlights the importance of compression and impression fossils in understanding the distribution of fossil taxa. This material also suggests that Cheirolepidiaceae cone scales can be easily confused with those of another common conifer family, the Araucariaceae, which has important implications for accurately understanding Mesozoic conifer diversity and paleoecology.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238520,"idioma_id":4,"titulo":"Exploring the interior of cuticles and compressions of fossil plants by FIB-SEM milling and image microscopy","resumen":"We present the first study of cuticles and compressions of fossilleaves by Focused Ion Beam Scanning Electron Microscopy(FIB-SEM). Cavities preserved inside fossil leaf compressionscorresponding to substomatal chambers have been observedfor the first time and several new features were identified in thecross-section cuts. These results open a new way in the investigationof the three-dimensional structures of both micro- andnanostructural features of fossil plants. Moreover, the applicationof the FIB-SEM technique to both fossils and extant plantremains represent a new source of taxonomical, palaeoenvironmentaland palaeoclimatic information.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238523,"idioma_id":4,"titulo":"Presence of the telescope fish Mendosoma lineatum in Patagonian waters, a new species in the ichthyological fauna from the south-west Atlantic Ocean","resumen":"ThepresenceofthetelescopefishMendosomalineatuminPatagonianwatersofArgentinaisreported. Mendosoma lineatum is the second species of the Latridae recorded in the south-west Atlantic Ocean and its presence in Patagonia is an addition to both the ichthyological fauna of the Argentinean Sea and the south-west Atlantic Ocean.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238531,"idioma_id":5,"titulo":"Determinación de residuos de Carbofuran en apios cultivados en la región de la que-brada de Humahuaca, provincia de Jujuy","resumen":"El objetivo del trabajo fue determinar residuos de Carbofuram en plantas de apio, cultivadas en la Quebrada de Humahuaca","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238532,"idioma_id":4,"titulo":"Particleboard Based on Rice Husk: Effect of Binder Content and Processing Conditions","resumen":"In the development of materials based on renewable resources, the search for lignocellulosic substitutes for wood is one of the biggest challenges that academia and the particleboard and wood industries are facing. In this article, particleboards were processed using rice husk, an agricultural waste, as a substitute for wood. Rice husk without any further treatment was processed into particleboards using phenol-formaldehyde resin as binder. The effect of the processing parameters, pressure and binder content (BC) on the density, water absorption (WA), thickness swelling (TS), modulus of rupture (MOR) and modulus of elasticity (MOE) was analyzed. The performance of the obtained panels was evaluated in comparison with the US Standard ANSI\/A208.1. Particleboards with 11% of BC met the minimum requirements of MOR and MOE recommended by the ANSI specifications for commercial use, while particleboards with high BC (14%) also accomplished the requirements for industrial use, finding a resourceful use for this agricultural waste.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238534,"idioma_id":4,"titulo":"Long-term stability of compressionmolded soybean protein concentrate films stored under specific conditions","resumen":"Post-processing evolution of the functional properties of soybean protein concentrate (SPC) films, plasticized with varying glycerol levels and processed by compression molding, was examined over a period of 90 days. Films stored in the glassy state (25±2ºC and 65±2% relative humidity) lost glycerol and water over time, as verified by gas chromatography and the decline in moisture content. SPC films plasticized by 40-50% glycerol showed a time-dependent increment of both the elastic modulus and the tensile strength, while the elongation, barrier properties, soluble mass and opacity of these films varied marginally with time. Contrary, films with 30% glycerol lost the most moisture and their elongation was reduced significantly, while water vapor permeability slightly increased upon aging. The performance of aged films resulted from the balance between loss of plasticizer and water, and the progressive replacement of unordered structures by intermolecular hydrogen bonded &#61538;-sheets and aggregates.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238538,"idioma_id":5,"titulo":"Sustentabilidad y Buen Vivir en la provincia de Santa Elena, Ecuador: aportes para la definición de indicadores compatibles","resumen":"La búsqueda y la selección de indicadores de sustentabilidad se considera fundamental para medir el buen vivir (BV) de las comunidades. El presente trabajo propone evaluar, en una primera aproximación, la sustentabilidad en las parroquias de la provincia de Santa Elena (Ecuador) mediante algunos de los indicadores considerados en el Plan Nacional para el Buen Vivir (2013-2017), a fin de analizar los alcances y las limitaciones de la operatividad de los mismos al aplicarlos en la escala parroquial. Para ello, se construyó un índice de sustentabilidad que integra veintiocho indicadores. Los índices más favorables se registran en aquellas parroquias con importantes áreas urbanas, en tanto que las más críticas son esencialmente rurales. Muchos de los indicadores demuestran una baja compatibilidad con la realidad concreta y se observan limitaciones como las referidas a la etnicidad de la población. Se espera abrir nuevas puertas a la búsqueda y al ajuste de indicadores de sustentabilidad y BV en la escala local.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238539,"idioma_id":5,"titulo":"Análisis exploratorio de datos espaciales: aplicación a las condiciones de habitabilidad en el periurbano de la ciudad de Mar del Plata, Argentina","resumen":"Las ciudades se expanden generando espacios de interfase urbano-rural complejos y dinámicos, cuya población manifiesta contrastes en las condiciones de habitabilidad. Eso sucede en el periurbano de Mar del Plata, donde estudios previos evalúan comparativamente estas condiciones en distintos momentos, mediante la construcción de un Índice de Condiciones de Habitabilidad (ICH). En ese marco, el presente trabajo propone realizar un análisis exploratorio de la evolución del ICH, considerando dos períodos: 1991-2001 y 2001-2011. Este proceso permite detectar las unidades espaciales con variaciones destacadas. Se utilizaron dos procedimientos: un gráfico en 3D y un gráfico de Coordenadas Paralelas, cuyos resultados se representaron espacialmente. Las unidades espaciales (radios censales) más beneficiadas se encuentran generalmente más cercanas al área urbana y en los sectores costeros, favorecidas por la expansión de los servicios. Si bien las mejoras se incrementaron a lo largo de los años, también se acentuaron las disparidades. El análisis exploratorio permitió detectar fácilmente los contrastes al interior del periurbano en distintos momentos, siendo su aplicación de utilidad para la gestión de áreas críticas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238541,"idioma_id":4,"titulo":"Characterization of microtubule buckling in living cells","resumen":"Microtubules are filamentous biopolymers involved in essential biological processes. They form key structures in eukaryotic cells, and thus it is very important to determine the mechanisms involved in the formation and maintenance of the microtubule network. Microtubule bucklings are transient and localized events commonly observed in living cells and characterized by a fast bending and its posterior relaxation. Active forces provided by molecular motors have been indicated as responsible for most of these rapid deformations. However, the factors that control the shape amplitude and the time scales of the rising and release stages remain unexplored. In this work, we study microtubule buckling in living cells using Xenopus laevis melanophores as a model system. We tracked single fluorescent microtubules from high temporal resolution (0.3&ndash;2 s) confocal movies. We recovered the center coordinates of the filaments with 10-nm precision and analyzed the amplitude of the deformation as a function of time. Using numerical simulations, we explored different force mechanisms resulting in microtubule bending. The simulated events reproduce many features observed for microtubules, suggesting that a mechanistic model captures the essential processes underlying microtubule buckling. Also, we studied the interplay between actively transported vesicles and the microtubule network using a two-color technique. Our results suggest that microtubules may affect transport indirectly besides serving as tracks of motor-driven organelles. For example, they could obstruct organelles at microtubule intersections or push them during filament mechanical relaxation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238542,"idioma_id":4,"titulo":"Artificial Bee Colony Optimization for Feature Selection of Traffic Sign Recognition","resumen":"This paper proposes the application of a swarm intelligence algorithm called Artificial Bee Colony (ABC) for the feature selection to feed a Random Forest (RF) classifier aiming to recognise Traffic Signs. In this paper, we define and assess several fitness functions for the feature selection stage. The idea is to minimise the correlation and maximise the entropy of a set of masks to be used for feature extraction results in a higher information gain and allows to reach recognition accuracies comparable with other state-of-art algorithms. The RF comprises as a committee based on decision trees, which allows handling large datasets and features with high performance, enabling a Traffic Sign Recognition (TSR) system oriented for real-time implementations. The German Traffic Sign Recognition Benchmark (GTSRB) was used for experiments, serving as a real basis for comparison of performance for our proposal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238544,"idioma_id":4,"titulo":"Analysis of genetic association using Hierarchical Clustering and Cluster Validation Indices","resumen":"It is usually assumed that co-expressed genes suggest co-regulation in the underlying regulatory network. Determining sets of co-expressed genes is an important task, where signi&#64257;cative groups of genes are de&#64257;ned based on some criteria. This task is usually performed by clustering algorithms, where the whole family of genes, or a subset of them, are clustered into meaningful groups based on their expression values in a set of experiment. In this work we used a methodology to obtain sets of co-expressed genes, based on the cluster validation indexes as a measure of cluster quality for individual gene groups, and a combination of several variants of hierarchical clustering to generate the candidate groups. The algorithm provides a balance between search time and detection rate. It avoids the full search, which can be impractical for large number of genes, with the cost of missing some good sets, but it is able to detect most of the top ranked sets, which is not usually possible by using only one clustering algorithm. The e&#64256;ectiveness of this algorithm is related to the ability of the validation clustering index to score properly compact groups, which are at the same time separated from other groups of genes. With this analysis we veri&#64257;ed the suitability of the proposed tool for the detection of sets of co-expressed genes, and we considered that it is useful for biologists or researchers in computational biology interested in generating new hypotheses about the co-expression of genes, or genomic markers like QTLs, which are not provided in most standard analysis tools. This algorithm will generate quickly a set of good groups on base of a clustering validation index, and combines the advantages of each variant of hierarchical clustering algorithm.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238547,"idioma_id":4,"titulo":"Altered expression of cytokines IL-1&#945;, IL-6, IL-8 and TNF-&#945; in bovine follicular persistence","resumen":"In dairy cattle, cystic ovarian disease (COD) is an important cause of subfertility, and two of the main signs are ovulation failure and follicularpersistence. The aim of this study was to examine the expression of the cytokines IL-1&#945;, IL-6, IL-8 and TNF-&#945; in ovarian follicular structures at different times of persistence in a model of follicular persistence induced by prolonged treatment with progesterone in dairy cows. Protein expression of IL-1&#945;, IL-6, IL-8 and TNF-&#945; was evaluated by immunohistochemistry. Additionally, IL-6 concentration in follicular fluid and serum was determined by ELISA. IL-1&#945;, IL-6, IL-8 and TNF-&#945; expression was increased in follicles with different persistence times in relation to the control dominant follicles, in granulosa cells. For IL-6, IL-8 and TNF-&#945;, this increase was detected early (P0: expected time of ovulation and\/or P5: 5 days of follicular persistence). Additionally, theca cells showed an increase in IL-6 in antral (groups P10 and P15) and persistent follicles (group P10) related to dominant follicles from the control group (p<0.05). Serum concentration of IL-6 was higher in groups P5, P10 and P15 than in control cows (p<0.05). The results show evidence that early development of COD in cows is concurrent with altered expression of these cytokines in different ovarian follicular structures and may contribute to the follicular persistence and endocrine changes found in cattle with follicular cysts.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238548,"idioma_id":4,"titulo":"Role of Components of the Insulin-like Growth Factor System in the Early Stages of Ovarian Follicular Persistence in Cattle","resumen":"Cystic ovarian disease (COD) is one of the main causes of infertility in dairy cattle. It has been postulated that the insulin-like growth factor (IGF) system may contribute to follicular persistence and development of COD. The initiation of the IGF response is a result of interactions between IGF-binding proteins (IGFBPs) and IGFBP proteases, mainly pregnancy-associated plasma protein A (PAPP-A). IGFBPs bind IGFs with high affinity and consequently regulate their access to IGF receptors (IGFRs). The aim of this research was to determine variations in components of the IGF system in the ovaries of cows with persistent follicles induced by long-term administration of progesterone. Proteins of the IGF system were evaluated at 0 (expected day of ovulation), 5, 10 and 15 days of follicular persistence to determine whether the changes occur early in the development of COD. The concentrations of IGF1 and IGFBP4 in follicular fluid were similar in all groups with follicular persistence and in control antral follicles. IGFR1 and IGFBP4 expression in situ were higher in granulose cells in persistent follicles than in control follicles. No differences were found in PAPP-A concentration within follicular fluid in persistent follicles relative to control antral follicles. These data support the hypothesis that the IGF system is altered in the initial stages of development of follicular persistence and has a determinant role in ovarian function in cattle.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238549,"idioma_id":4,"titulo":"Changes in the proliferation\/apoptosis balance in the ovary: a key early event in bovine follicular persistence","resumen":"The objective of this work was to evaluate proliferation and apoptosis in the bovine ovary in a model of follicular persistence induced by low levels of progesterone, to detect incipient changes during COD development, on the expected day of ovulation (day 0) and after 5, 10 and 15 days of follicular persistence. We analyzed cell proliferation by evaluating the expression of Ki-67 and apoptosis by evaluating caspase-3, BAX and BCL2 expression. Proliferation was similar in the granulosa and theca cells of antral follicles in P0 (treated with progesterone up to the expected day of ovulation) and in the control group. A decrease in cell proliferation was detected after 5 days of persistence (P5) in relation to P0 (p<0.05). Similar changes were found in the granulosa cells of the persistent follicles in relation to the control group (p<0.05). Caspase-3 expression was similar in granulosa cells of antral follicles at early stages of persistence, with an increase after 15 days of persistence (p<0.05). In granulosa cells of group P10 (10 days of persistence), caspase-3 expression was reduced relative to that of antral follicles from the control group (p<0.05). BCL2 expression was higher in granulosa cells of the persistent follicles of group P0 relative to the control follicles, with no changes in BAX expression, which was increased in persistent follicles of group P15 (p<0.05). Similar results were observed in theca cells at initial stages of persistence. The results show that, initially, proliferation is maintained with low apoptosis and an increase in cell survival.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238551,"idioma_id":4,"titulo":"Maternal knowledge and use of galactagogues in Andean communities of Peru.","resumen":"--------- Forwarded message ----------From: Jonathan Dombrosky Date: Mon, Aug 7, 2017 at 5:51 PMSubject: [EBL] Proof Ready for Review and AuthorizationTo: 'madamonteban@gmail.com'  Dear Dr. Monteban, Your recent manuscript entitled ?Maternal Knowledge and Use of Galactagogues in Andean Communities of Cusco, Peru? has been copyedited and formatted for your review and authorization (attached). Please treat this file as your final proofs and your last opportunity to edit the text prior to publication. It is important to verify all contents using track changes to mark anything you would like to correct or adjust prior to publication. We have identified the following copyediting issues: 1.The abstract exceeds the 250 word limit.2.The bio statement uploaded to OJS needs to be revised. Please add in a short bio statement (around 25 words in length) to the body of the email confirming that you have reviewed and approved your proof. Please also be sure to check author names, affiliations, and contact information.  If no additional issues arise during our production process, your paper will be converted into PDF and HTML galleys and may be published without further action by you. Please note that the attached document will be used to create the HTML version of your paper. Thus, any spacing issues?or issues with ?widowed? and\/or ?orphaned? text?will not appear in your galleys. It is important that the MS Word document flows continuously for HTML conversion. If you have any questions, please feel free to contact me. Best regards, Jonathan DombroskyProduction Editor | Ethnobiology LettersWeb and Social Media Liaison | Society of EthnobiologyABSTRACTA commonly reported reason for early breastfeeding cessation is inadequate milk production. In response, women across the globe turn to natural galactagogues ? substances used to increase the milk supply. Andean women hold traditional knowledge about the medicinal and nutritional properties of plants and animals that are good to eat during breastfeeding. This research explores the maintenance and use of galactagogues, and specifically the use of the Andean flicker bird. The research examines the use of galactagogues within the wider framework of breastfeeding, nutrition, and public health policies in Perú.To elicit maternal knowledge and use of galactagogues, semi-structured and free-listing interviews were conducted with 33 mothers. Data analysis calculated the frequency and percentage of women reporting each type of galactagogue. In addition, thematic codes and relevant text passages were used in an iterative analytic process to document emerging themes.Identified galactagogues included five plants and six animals. Several galactagogues included protein-rich foods such as quinoa, lamb meat, and the Andean Flicker bird. The use of protein-rich galactagogues as solid food is reinforced by public health messages. Galactagogues in the research communities are usually consumed as soups or drinks that are less rich in proteins than solid meals. However, the potential role of galactagogues consumed in liquid form, in the maintenance of appropriate hydration levels during breastfeeding in an environment where safe drinking water is scarce, is a new contribution to the existing literature. The results are relevant to the design of maternal and child health policies that comply with intercultural health premises that value and respect the knowledge and practices of Andean Peoples.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238553,"idioma_id":4,"titulo":"Bite it forward &hellip; bite it better? Incisor procumbency and mechanical advantage in the chisel-tooth and scratch-digger genus Ctenomys (Caviomorpha, Rodentia)","resumen":"The subterranean genus Ctenomys (&#8764;60 species, &#8764;100?1000&nbsp;g) constructs its burrows by using both forefeet and teeth throughout a wide range of habitats in South America. They show a high variation in the incisors? angle of attack (procumbency) and a mostly conserved skull morphology, not only amongst their congeners, but within the caviomorph rodents. Traditionally, procumbency has been largely related to tooth-digging. Looking for the possible influence of incisor procumbency on the mechanical advantage (MA) of each of the seven jaw adductor muscles in the genus, we examined 165 skulls representing 24 species. We also evaluated the role of two other relevant traits ? i.e. mandibular width and diastema length ? in jaw biomechanics and the existence of a relationship between procumbency angle and soil hardness. The in- and out-lever arms (Li and Lo) of the involve muscles were determined based on their insertion?s 3D-coordinates and integrated to calculate their MA. Interspecific scaling relationships for skull and muscle measurements were analyzed through reduced major axis regression performed with phylogenetically independent standardized contrasts. Although the procumbency angle ranged between &#8764;92.5° (C. mendocinus) and &#8764;107.2 (C. occultus), we found that it was not significantly correlated with the MA of any jaw adductor muscle. This study also showed that the incisor procumbency variation was not associated with the relative rostral length or soil hardness. This result contradicts previous generalizations about a correlation between habitat conditions and the procumbency of the incisors in subterranean rodents. In sum, our results suggest that, within Ctenomys, possessing more procumbent incisors may not represent a biomechanical advantage, but might be beneficial in other aspects related to chisel-tooth digging or food processing behaviors.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238554,"idioma_id":5,"titulo":"Resistencia a herbicidas. Situación actual en el sudeste bonaerense","resumen":"El principal factor involucrado que conduce a un aumento de la proporción de individuos resistentes es la presión de selección impuesta por el uso repetido de un mismo herbicida o de herbicidas con el mismo modo de acción. Así, el manejo de poblaciones resistentes y la prevención de nuevos casos de resistencia requieren incorporar diversas prácticas de manejo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238556,"idioma_id":5,"titulo":"Relación entre el gen Rps 1k y la resistencia a Pythium ultimum y P. irregulare en soja","resumen":"En el cultivo de soja Pythium spp. produce la pudrición de semillas y raíces, y ?damping off?. El objetivo del presente trabajo fue verificar la relación entre el gen Rps 1k de resistencia a Phytophthora sojae y P. ultimum y P. irregulare. Cuatro genotipos de soja, dos con el gen Rps 1k (SE+1y SE+2) y dos sin el gen (SE-1 y SE-2) se sembraron en suelo inoculado y sin inóculo. Los genotipos SE-1 y SE-2 no difirieron entre sí, ya sea que estuviesen inoculados o no, ni tampoco difirieron del SE+2. En cambio, los genotipos con el gen Rps1k difirieron entre sí, tanto los que estuvieron inoculados como los no inoculados. SE+2 presentó un 95% de emergencia mientras que SE+1 presentó un 78.35% de emergencia pero en ambos casos la emergencia disminuyó cuando se inoculó, con 63.35% y 34.15% respectivamente. Bajo las condiciones del presente ensayo las variedades utilizadas conteniendo el gen Rps 1k a Ph. sojae no presentaron mayor número de plántulas emergidas frente a las cepas probadas de P. ultimum ni de P. irregulare.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238557,"idioma_id":4,"titulo":"Classification of Reynolds phytoplankton functional groups using individual traits and machine learning techniques","resumen":"The Reynolds Functional Groups (RFG) classification scheme is an informativeand widely used method in ecological studies of freshwater phytoplankton. Itclusters species with similar traits, as well as common environmental sensitivitiesand tolerances. However, researchers face the difficulty to classify species intoRFG because it relies in expert opinion, taxonomical knowledge and environmentalinformation, which are not always accessible. Thus, a step forward is to buildgeneral statistical models to classify species into RFG.2. Under the hypothesis that an organism?s response to environmentalconditions determines their functional traits, here represented by the RFG, wepredict that morphology and classification into broad taxonomic groupswill explain RFG independently from environmental information and expertknowledge.3. To evaluate the predictive ability of morphological traits (e.g. volume) and taxonomicaffiliation (e.g. chroococcal Cyanobacteria) as discriminant variables ofRFG, we compiled 1,300 species (264 waterbodies) and applied Random Forest(RF) and Classification and Regression Trees (CART). We divided the data to trainthe models and test their performance.4. RF successfully classified species into the 28 RFG (only c. 10% test error) withan average individual RFG success rate of 84.6 (range = 33%?100%). This is arelatively high percentage of success from an ecological point of view. It suggeststhat the selected variables are able to reconstruct the RFG and representwell environmental preferences, without including information about local environmentalconditions as classifiers, information that was available for the classificationby experts.5. Our results reinforce the functional basis of the RFG as defined by Reynolds(Reynolds et al., 2002, J. Plankton Res. 24, 417?428) and support bothmorphological traits and taxonomic classification as good proxies of phytoplanktonresponses to environmental conditions. A dichotomous key based inthe CART was constructed and an R code to classify species into the RFG isfreely available. This work may help users to classify species into the RFG,including those that were not previously listed in Reynolds classificationsystem.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238558,"idioma_id":4,"titulo":"Pairing in the BCS and LN approximations using continuum single particle level density","resumen":"Understanding the properties of drip line nuclei requires to take into account the correlations with the continuum spectrum of energy of the system. This paper has the purpose to show that the continuum single particle level density is a convenient way to consider the pairing correlation in the continuum. Isospin mean-field and isospin pairing strength are used to find the Bardeen?Cooper?Schrieffer (BCS) and Lipkin?Nogami (LN) approximate solutions of the pairing Hamiltonian. Several physical properties of the whole chain of the Tin isotope, as gap parameter, Fermi level, binding energy, and one- and two-neutron separation energies, were calculated and compared with other methods and with experimental data when they exist. It is shown that the use of the continuum single particle level density is an economical way to include explicitly the correlations with the continuum spectrum of energy in large scale mass calculation. It is also shown that the computed properties are in good agreement with experimental data and with more sophisticated treatment of the pairing interaction.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238559,"idioma_id":5,"titulo":"Modelización lineal de un sistema masa-resorte real","resumen":"De acuerdo al modelo enseñado en los cursos introductorios universitarios, la frecuencia de las oscilaciones libres de un sistema masa-resorte vertical, en el caso de fuerzas disipativas y masa del resorte despreciables, puede calcularse simplemente como la raíz cuadrada de la relación entre la gravedad del lugar y el estiramiento producido por el cuerpo sujeto al resorte. Sin embargo, cuando se utiliza un resorte real, las frecuencias medidas difieren en forma notable por debajo de las previstas por el modelo. El análisis de la respuesta estática del resorte a la carga revela que no obedece la ley de Hooke e impide definir una única constante elástica k E en cualquier condición de carga. Haciendo una aproximación lineal de esta respuesta alrededor del punto de trabajo y definiendo una constante dinámica k D , la resolución de la ecuación diferencial de movimiento predice un valor de la frecuencia mucho más cercano al medido. Una posterior corrección heurística, que toma en cuenta la masa del resorte, hace disminuir aún más la discrepancia relativa. Nuestro análisis concluye que los fenómenos disipativos soninsignificantes comparados con la elasticidad y la inercia del sistema estudiado. Este problema y su solución muestran la necesidad de discutir en las aulas la modelización de este fenómeno físico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238560,"idioma_id":4,"titulo":"Damaging micromechanisms in ferritic ductile cast iron in as-cast and ferritized condition","resumen":"Mechanical behavior and damaging micromechanisms in Ductile Cast Irons (DCIs) are strongly effected by matrix microstructure (e.g., phases volume fraction, grains size and grain distribution) and graphite nodules morphology peculiarities (e.g., nodularity level, dimension, distribution etc.). The influence of the graphite nodules depends both on the matrix microstructure and the loading conditions (e.g., static, quasi-static or cyclic loadings). According to the most recent results, these graphite nodules show a mechanical properties gradient inside the graphite nodules, with the graphite elements ? matrix debonding as only one of the possible damaging micromechanisms. In this work, two different DCIs were investigated (with a ferritic and a ferritized matrix) focusing the damaging micromechanisms in graphite nodules due to tensile stress. Specimens lateral surfaces were observed using a Scanning Electron Microscope (SEM) during the tests following a step by step procedure.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238561,"idioma_id":4,"titulo":"Multi-scale analysis of the early damage mechanics of ferritized ductile iron","resumen":"A multi-scale analysis of the linear elastic and the early damage stages of ferritic ductile iron is introduced in this work. The methodology combines numerical and experimental analyses in the macro and micro scales. Experiments in the micro-scale are used for the characterization of the material micro constituents and the assessment of the micro-scale damage mechanisms; experiments in the macro-scale provide the data to calibrate and validate the models. The 2D multi-scale problem is modeled using the pre-critical regime of the Failure-Oriented Multi-Scale Variational Formulation (FOMF), which is implemented via a FE2 approach. Finite element analysis in the micro-scale is customized to account for plastic deformation and matrix-nodule debonding. The multi-scale model is found effective for capturing the sequence and extent of the damage mechanisms in the micro-scale and to estimate, via inverse analyses, the parameters of the matrix-nodule debonding law. Results allow to develop new insights for the better understanding of the ductile iron damage mechanics and to draw conclusions related to the modeling aspects of the multi-scale simulation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238562,"idioma_id":4,"titulo":"Ephemeral parasitism on blooming diatoms in a temperate estuary","resumen":"Parasites of phytoplankton influence phytoplankton bloom dynamics and may severely affect the type of food available for higher trophic levels. The incidence of parasitic infections generally is expected to increase across ecosystems worldwide under the scenario of global change. Herein we report on a massive parasite infection on two dominant diatoms of the austral winter bloom, namely Thalassiosira pacifica and Chaetoceros diadema, recorded during an extreme precipitation period in the Bahía Blanca Estuary, Argentina. The parasite infection was concomitant with a marked drop in water salinity and affected more than 40% of host cells. Although the parasite on C. diadema was not identified, the parasite on T. pacifica was most likely Pirsonia sp., a nanoflagellate with high host specificity. After the intense rainy period and the parasitic infection, the phytoplankton biomass dropped (by more than 80%) and the community structure shifted to one with smaller species (i.e. Thalassiosira curviseriata, T. hibernalis and T. minima). We discuss the implications that these modifications may have on the food web dynamics and the potential relationship between precipitation-driven modifications in water properties and the emergence of parasitism in coastal eutrophic environments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238563,"idioma_id":4,"titulo":"Time-varying environmental control of phytoplankton in a changing estuarine system","resumen":"Estuaries are among the most valuable aquatic systems by their services to human welfare. However, increasing human activities at the watershed along with the pressure of climate change are fostering the co-occurrence of multiple environmental drivers, and warn of potential negative impacts on estuaries resources. At present, no clear understanding of how coastal ecosystems will respond to the non-stationary effect of multiple drivers. Here we analysed the temporal interaction among multiple environmental drivers and their changing priority on shaping phytoplankton response in the Bahía Blanca Estuary, SW Atlantic Ocean. The interaction among environmental drivers and the number of significant direct and indirect effects on chlorophyll concentration increased over time in concurrence with enhanced anthropogenic stress, changing winter climate and wind patterns. Over the period 1978?1993, proximal variables such as nutrients, water temperature and salinity, showed a dominant effect on chlorophyll, whereas in more recent years (1993?2009) climate signals (SAM and ENSO) boosted indirect effects through its influence on precipitation, wind, water temperature and turbidity. Turbidity emerged as the dominant driver of chlorophyll while in recent years acted synergistically with the concentration of dissolved nitrogen. As a result, chlorophyll concentration showed a significant negative trend and a loss of seasonal peaks reflecting a pronounced reorganisation of the phytoplankton community. We stress the need to account for the changing priority of drivers to understand, and eventually forecast, biological responses under projected scenarios of global anthropogenic change.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238564,"idioma_id":4,"titulo":"Interaction of galacto-oligosaccharides and lactulose with dipalmitoylphosphatidilcholine lipid membranes as determined by infrared spectroscopy","resumen":"Lactulose and galacto-oligosaccharides (GOS) have been recognized as health promoting compounds dueto their recognized prebiotic capacity. In addition, because of their polyhydroxilated nature, they areeffective protectants during processes involving dehydration of lactic acid bacteria. The protectiveeffects of sugars have been associated with their capacity to replace water molecules from lipidmembranes and\/or to form glassy matrices. Although this latter property has been previouslyinvestigated for GOS and lactulose, the capacity of these sugars to replace water molecules was not.Furthermore, it must be considered that GOS are usually mixtures of oligo-saccharides with differentdegrees of polymerization (DP) including or excluding different amounts of mono and disaccharides, andthe effect of their composition on the GOS-membrane interaction has not been addressed so far. Theaim of the present work was to study the interaction of lactulose and GOS of different compositionswith dipalmitoylphosphatidilcholine (DPPC) membranes both in the gel (Lb) and in the liquid crystallinephase (La) by using infrared spectroscopy. Both GOS and lactulose interacted with the phosphate groupsof the polar head region, but only lactulose (disaccharide) penetrated into the lipid bilayers anddecreased the membrane phase transition (Tm). In contrast, GOS containing no mono and disaccharideswere excluded from the hydrophobic region, leading to an increase of the Tm. In turn, GOS containingmono and disaccharides showed a concentration-dependent effect. The results obtained shed light onthe mechanisms involved in protection mediated by GOS and lactulose, thus providing support toimprove the stabilization of lactic acid bacteria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238565,"idioma_id":4,"titulo":"Substrate binding and specificity appear as major forces in the functional diversification of eqolisins.","resumen":"Background: Eqolisins are rare acid proteases found in archaea, bacteria and fungi. Certain fungi secrete acids as part of their lifestyle and interestingly these also have many eqolisin paralogs, up to seven paralogs have been recorded. This suggest functional redundancy and diversification, which was the subject of the research we performed and describe here.  Results: We identified eqolisin homologs by means of iterative HMMER analysis of the NR database. The identified sequences were scrutinized for which we defined novel hallmarks, identified by molecular dynamics simulations of mutants of highly conserved positions, using the structure of an eqolisin that was crystallized in the presence of a transition state inhibitor. Four conserved glycines were shown to be required for functionality. A mutation of W67F is shown to be accompanied by the L105W mutation. Molecular dynamics shows that the W67 binds to the substrate via a  &#960;-&#960; stacking and a salt bridge. The latter is stronger in the W67F\/L105W double mutant. Additional likely fatal mutants are discussed. Upon sequence scrutiny we obtained a set of 233 sequences that in all likelihood lacks false positives. This was used to reconstruct a Bayesian phylogenetic tree. We identified 14 specificity determining positions. These occur in two pairs that are explained by structural constraints as well as two sub-networks of real specificity determining positions. The first sub-network is related to substrate specificity whereas the second sub-network seems to affect the dynamics of three loops that are involved in substrate binding.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238566,"idioma_id":4,"titulo":"Macroporous mullite materials prepared by novel shaping strategies based on starch thermogelation for thermal insulation","resumen":"A rigorous microstructural analysis of porous mullite materials developed using novel shaping strategies based on the starch consolidation casting, and their thermal properties in relation to the processing and starch type were accomplished in view of their use as thermal insulators. In order to characterize the size and morphology of pore, basic size and 2D shape factors, and global 3D stereological parameters were determined using microscopy techniques. Results indicated that the porosity volume, pore connectivity degree, and mean free path were the determining factors of the lowest heat transfer by conduction registered in materials prepared with cassava starch. This material is the best candidate to be used in thermal insulation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238567,"idioma_id":4,"titulo":"Daily activity pattern of reintroduced giant anteaters (Myrmecophaga tridactyla): effects of seasonality and experience","resumen":"We assessed the effect of seasonality and intrinsic conditions on daily activity pattern of giant anteaters reintroduced in the Iberá Reserve, Argentina. During2007?2012 we gathered 159 24-h focal samples on 15 radiomarked individuals (11 captive-reared, four wild-reared; seven adults, eight juveniles), 216 records of beginning and end of activity bouts on 20 individuals, and 454 camera-traps records (3345 trap-days). We estimated the daily hours of activity, the percentage of diurnal and nocturnal activity, and the daily activity range and time overlap using time as a circular variable in kernel density estimations.We assessed differences between seasons, sexes, age classes, and types of rearing. The average daily hours of activity was 8:43 h. Camera-traps and radio-telemetry showed similar results. Animals exhibited both diurnal (60?65%) and nocturnal (40?35%) activity. The higher probability for being active ranged within 09:00?03:00 h. Anteaters spent more hours active and were more nocturnalduring summer. Activity was highly overlapped between sexes, and wild-reared individuals were more nocturnal than captive-reared ones. Seasonal shifts indaily activity highlights the importance of thermoregulation as a selective factor in this species. The giant anteater is a cathemeral species with flexibility to accommodate its activity pattern to local conditions or experience.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238568,"idioma_id":4,"titulo":"The Giant armadillo (Priodontes maximus) in the Argentine Chaco","resumen":"The giant armadillo (Priodontes maximus) is a difficult species to study because of low population densities, combined with nocturnal and fossorial habits. No systematic population studies have been undertaken to date in Argentina. Our objectives were to evaluate the species? presence, relative abundance, and temporal activity patterns across five locations with different levels of human disturbance and legal protection in the Argentine Chaco. Between June 2006 and January 2014, we completed 10 surveys, using camera trap and \/ or track plots, searches for burrows and tracks, and observations by local people and park rangers. We used camera trap records to determine presence, relative abundance (records \/ 100 camera days) and activity patterns. We only recorded the species at three locations: Copo National Park, Aborigen Reserve and La Fidelidad Resource Reserve. At the Aborigen Reserve we documented burrows and tracks but obtained no photographs. At Copo and La Fidelidad we estimated relative abundance at 0.08 and 0.40 records per 100 camera days, respectively. We did not record giant armadillos near the edges of La Fidelidad, nor in the two locations with greater human disturbance. Camera trap records indicate that giant armadillos in the Argentine Chaco are strongly nocturnal. The population status of giant armadillos in Argentina is a matter of concern. With few or no records at other study locations, La Fidelidad may harbor one of the few relict populations of giant armadillos in the Argentine Chaco.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238571,"idioma_id":4,"titulo":"Bubble nucleation and growth in very strong cosmological phase transitions","resumen":"Strongly first-order phase transitions, i.e., those with a large order parameter, are characterized by a considerable supercooling and high velocities of phase transition fronts. A very strong phase transition may have important cosmological consequences due to the departures from equilibrium caused in the plasma. In general, there is a limit to the strength, since the metastability of the old phase may prevent the transition to complete. Near this limit, the bubble nucleation rate achieves a maximum and thus departs from the widely assumed behavior in which it grows exponentially with time. We study the dynamics of this kind of phase transitions. We show that in some cases a gaussian approximation for the nucleation rate is more suitable, and in such a case we solve analytically the evolution of the phase transition. We compare the gaussian and exponential approximations with realistic cases and we determine their ranges of validity. We also discuss the implications for cosmic remnants such as gravitational waves.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238575,"idioma_id":4,"titulo":"Healing Cream Tournefortia hirsutissima L","resumen":"Objective: Investigate the active compounds of Tournefortia hirsutissima L. to determine the compoundsresponsible for the cicatrizing effect. Furthermore, create a topic formulation with the extract of the plant toaccelerate the healing process.Methods: The compounds of the plant were characterized before with a Gas Chromatography? MassSpectrometry (GC-MS). To extract the compounds, it was used a steam distillation, solvent extraction andMicrowave Assisted Extraction (MAE) and it was compared the efficiency of each method. AResults: After the investigation of each compound, it was found that palmitic acid induces the regeneration ofkeratocytes. Furthermore gamma-sitosterol accelerates keratinocyte migration by eliminating ROS. In the extractionmethods of Tournefortia hirsutissima L. and carrot, the Microwave Assisted Extraction had the best efficiency. Aninhibitory halo, around the cream and the extract of the plant, was shown in the antibiogram using a massive spreadof Staphylococcus aureus.Conclusion: After the investigation of each compounds of Tournefortia hirsutissima L., it can be concluded thatplant has compounds that accelerate healing by inducing the production of keratocytes in the skin and reduce levelsof oxidative stress. Furthermore, the plant inhibits growth of Staphylococcus aureus, so the plant has an antibioticeffect","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238576,"idioma_id":4,"titulo":"Chromatographic matrix based on hydrogel-coated reticulated polyurethane foams, prepared by gamma irradiation","resumen":"Novel chromatographic materials for protein purification with high adsorption capacity and fouling resistance are highly demanded to improve downstream processes. Here, we describe a novel adsorptive material based on reticulated polyurethane foam (rPUF) coated with a functional hydrogel layer. rPUF provides physical rigidity through its macroscopic structure, whereas the hydrogel layer provides capacity to adsorb proteins by specific interactions. The hydrogel coating process was performed by the dip-coating method, using a polyvinyl alcohol (PVA) solution. The PVA hydrogel was linked to the rPUF material by using a radiation-induced crosslinking process in aqueous ethanol solution. The ethanol in the solvent mixture allowed a balance between PVA swelling and PVA dissolution during the irradiation step. The resulting material showed higher thermal stability than the non-irradiated one. In addition, a simultaneous radiation-induced grafting polymerization (SRIGP) was done by simple addition of glycidyl methacrylate monomer into the irradiation solution. In a further step, sulfonic ligands were included specifically in the hydrogel layer, which contained around 200% of PVA respect to the original rPUF. Materials were characterized by FT-IR, thermogravimetric analysis, SEM microscopy and EDX analysis. The cation-exchange rPUF material was functionally characterized by the Langmuir isotherm and a dynamic adsorption experiment to analyze the chromatographic properties for protein purification processes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238577,"idioma_id":5,"titulo":"¿Cómo generar un modelo tridimensional in vitro a partir de un adenocarcinoma mamario murino?","resumen":"Las mamosferas son un modelo esferoide tumoral multicelular. Estas son utilizadas como un sistema de cultivo que se asemeja a la tridimensionalidad de los tumores. En este trabajo, hemos desarrollado este modelo utilizando un adenocarcinoma mamario murino con el fin de poder estudiar la fisiología tumoral y posibles aplicaciones terapéuticas. Se han probado diversas técnicas descriptas en trabajos previos. La mejor condición fue usar placas multiwells-96 en forma de V con la adición de una monocapa de agarosa, ya que se generaron esferas compactas y robustas. Además, hemos realizado tinciones histológicas de las mamosferas con hematoxilina-eosina para la observación de su estructura mediante microscopia óptica, y técnicas de inmunohistoquímica para evaluar el índice de proliferación celular y de neovascularización, con bromodeoxiuridina y VEGF (factor de crecimiento de endotelio vascular), respectivamente. Además, hemos estudiado la formación de estas mamosferas utilizando células tumorales y células madre mesenquimales derivadas de cordones umbilicales humanos para evaluar su interacción.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238578,"idioma_id":4,"titulo":"Physical mapping of QTL for tuber yield, starch content and starch yield in tetraploid potato (Solanum tuberosum L.) by means of genome wide genotyping by sequencing and the 8.3&nbsp;K SolCAP SNP array","resumen":"BackgroundTuber yield and starch content of the cultivated potato are complex traits of decisive importance for breeding improved varieties. Natural variation of tuber yield and starch content depends on the environment and on multiple, mostly unknown genetic factors. Dissection and molecular identification of the genes and their natural allelic variants controlling these complex traits will lead to the development of diagnostic DNA-based markers, by which precision and efficiency of selection can be increased (precision breeding).ResultsThree case-control populations were assembled from tetraploid potato cultivars based on maximizing the differences between high and low tuber yield (TY), starch content (TSC) and starch yield (TSY, arithmetic product of TY and TSC). The case-control populations were genotyped by restriction-site associated DNA sequencing (RADseq) and the 8.3 k SolCAP SNP genotyping array. The allele frequencies of single nucleotide polymorphisms (SNPs) were compared between cases and controls. RADseq identified, depending on data filtering criteria, between 6664 and 450 genes with one or more differential SNPs for one, two or all three traits. Differential SNPs in 275 genes were detected using the SolCAP array. A genome wide association study using the SolCAP array on an independent, unselected population identified SNPs associated with tuber starch content in 117 genes. Physical mapping of the genes containing differential or associated SNPs, and comparisons between the two genome wide genotyping methods and two different populations identified genome segments on all twelve potato chromosomes harboring one or more quantitative trait loci (QTL) for TY, TSC and TSY.ConclusionsSeveral hundred genes control tuber yield and starch content in potato. They are unequally distributed on all potato chromosomes, forming clusters between 0.5?4 Mbp width. The largest fraction of these genes had unknown function, followed by genes with putative signalling and regulatory functions. The genetic control of tuber yield and starch content is interlinked. Most differential SNPs affecting both traits had antagonistic effects: The allele increasing TY decreased TSC and vice versa. Exceptions were 89 SNP alleles which had synergistic effects on TY, TSC and TSY. These and the corresponding genes are primary targets for developing diagnostic markers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238579,"idioma_id":5,"titulo":"Respuesta al control de enfermedades foliares en ambientes con diferentes niveles de nitrógeno","resumen":"Algunos trabajos sostienen que ante un agregado de nitrógeno (N) puede verse favorecido el desarrollo de las enfermedades por diversas interacciones planta-patógeno, sin embargo existen evidencias que demuestran lo contrario. El objetivo de este trabajo fue evaluar el impacto de dos estrategias de control de enfermedades foliares en cultivos de trigo creciendo en condiciones contrastantes de fertilización nitrogenada (alta y baja disponibilidad, N0 y N1 respectivamente). Para ello se realizaron dos experimentos con objetivos diferentes: (i) evaluar el control de las enfermedades foliares utilizando dos estrategias de control en ambientes de baja y de alta disponibilidad de nitrógeno; y (ii) evaluar el impacto fisiológico de dos grupos diferentes de fungicidas (triazoles y estrobilurinas) en ambientes de baja y de alta disponibilidad de nitrógeno. La principal enfermedad fue ?roya de la hoja? (Puccinia tritici Eriksson), la que en la situación de N1 se inició antes respecto a N0. No existieron diferencias en los valores índices de verdor entre cultivos enfermos y sanos (tratamiento convencional). Sin embargo, las sucesivas aplicaciones de fungicida (control total) generaron diferencias en los valores de los índices de verdor en hoja respecto a los otros dos tratamientos. Existieron diferencias significativas en el rendimiento y en el número de granos tanto para la variable disponibilidad de N como para las diferentes estrategias de control de la enfermedad. En N1 se encontraron mayores valores de fotosíntesis. Sin embargo, ninguna diferencia estadísticamente significativa fue encontrada entre ambos principios activos en cuanto a los niveles de fotosíntesis foliar en hoja bandera a lo largo del llenado de los granos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238580,"idioma_id":4,"titulo":"Genetic progress in the Argentine bread wheat varieties released between 1918 and 2011","resumen":"The objective of this study is to update the data of genetic progress in bread wheat cultivars released in Argentina from 1918 to 2011 (emphasizing the last 20 years) characterizing different agronomic traits of interest for breeders. Experiments were carried out with a wide range of bread wheat cultivars and conducted under field conditions without nutritional and water restrictions. Yields showed a significant (R2=0.68) tri-linear trend when associated with the cultivar?s year of release. Until the 40s, when the first inflection point occurred, the genetic progress in terms of yield was 0.8 kg ha-1 yr-1 (0.02 % yr-1). Between 1940 and 1999, yield genetic progress reached its highest value (51 kg ha-1 yr-1; 1.17 % yr-1) but changed after 1999 when values became lower compared to the previous period, showing a value of 14 kg ha-1 yr-1 (0.18 % yr-1). Changes in grain yield were mostly explained by increases in harvest index and not by those in above-ground biomass. Plant height showed a negative bi-linear trend with the year of release, reaching an inflexion point well before the introgression of semi-dwarfing genes in commercial cultivars. Grain number increased ca. 63% when modern cultivars were compared to older ones, which explains most of the grain yield changes. In contrast to grain number, no significant differences between old and modern cultivars were found for grain weight, with average values of ca. 30 mg grain-1 for all environments explored.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238582,"idioma_id":4,"titulo":"Trypsin and N-aminopeptidase (APN) activities in the hepatopancreas of an intertidal euryhaline crab: biochemical characteristics and differential modulation by histamine and salinity","resumen":"AbstractNo studies are available about biochemical characteristics and modulation (i.e. by endogenous and\/or environmental cues) of trypsin (a key digestive endoprotease) in hepatopancreas of intertidal euryhaline crabs neither on the possible concomitant modulation of key ectoproteases such as aminopeptidase-N (APN) involved in final steps of protein digestion. Furthermore, nothing is still known in decapods crustaceans about the role of histamine as primary chemical messenger for modulation of main components of digestive process (i.e. proteases). We determined biochemical characteristics and investigated the effect of histamine injections; of histamine in vitro and of acclimation of individuals to low and high salinity on trypsin and aminopeptidase-N (APN) activities in the hepatopancreas of the euryhaline crab Cyrtograpsus angulatus (Dana 1851). Trypsin activity was maximal at pH 7.4 and at 45 °C. APN activity increased from pH 6.6 to 7.6?9.0 and was maintained high at 37?45 °C. Both activities exhibited Michaelis-Menten kinetics (apparent Km: trypsin = 0.36 mM; APN = 0.07 mM). The injection of 10&#8722; 4 M histamine decreased trypsin activity (about 40%) in hepatopancreas while did not affect APN activity. Similarly, in vitro 10-4 M histamine decreased trypsin activity (about 52%) in hepatopancreas but not APN activity. Trypsin activity in the hepatopancreas was not affected by acclimation of crabs to low (10 psu) or high (40 psu) environmental salinity while APN activity was increased (about 200%) in 10 psu. The results show the differential modulation of trypsin and APN by distinct cues and point to histamine as modulator of intracellular trypsin by direct action on the hepatopancreas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238583,"idioma_id":4,"titulo":"Interplay between stochastic and deterministic processes in the maintenance of alternative community states in Verrucomicrobia-dominated shallow lakes","resumen":"We analyzed the interplay between neutral and deterministic processes in maintaining contrasting alternative bacterioplankton communities through time in highly productive shallow lakes and we evaluated the relevance of these processes when a regime shift from a clear to a turbid state occurred. We observed that local assembly isruled primary deterministically, via local habitat filtering, with a secondary role of stochastic processes. We also found a hierarchy in the environmental sorting: while an unusual Verrucomicrobia dominance characterizes the three systems, local conditions limit within-bacterial community membership to closely phylogenetically related and ecologically similar taxa. These results indicate that bacterial abilities to establish in these lakes are strongly determined by their traits, and point toward special physiological adaptations to persist when these systems undergo a regime shift. Altogether, these results hint to a divergence in function among these alternative communities, mediated by major shifts in bacterial community trait structure, particularly regarding carbon use.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238584,"idioma_id":5,"titulo":"Composite membranes: surface properties and thermal stability","resumen":"The composite membraneswere manufactured with crosslinking poly(vinyl alcohol) on polyethersulfoneporous membranes by coating process. PES membranes were exposed to air plasmafor the purpose of surface modification. The coating of the support membranewas carried out by using a polymer matrix with a crosslinking agent. Thephysico-chemical properties have been studied by attenuated total reflectancefourier transform infrared spectroscopy (ATR-FTIR) and contact anglemeasurements. Thermal stability properties and phases transition of thecomposite membranes were investigated by thermal gravimetric analysis (TGA) anddifferential scanning calorimetry (DSC). Poly(vinyl alcohol) is water-soluble,hydrophilic and biodegradable polymer with excellent film forming properties.However, PVA must be crosslinked by modification reactions with a crosslinkingagent to form a stable membrane with good mechanical properties inpervaporation. PVA was used as the dense polymer with maleic acid as acrosslinking agent. Fourier transformed infrared spectroscopy revealed thenature of the surface chemical. Contact angle measurements have been used forevaluating changes in wetting properties. The air-plasma treatment caused aneffective surface modification. The mechanism responsible for the wettabilityimprovement was the surface functionalization by insertion of polar groups.Introduction of maleic acid into the polymer chain increased theamorphous region of the membrane. The PVA is a semi-crystalline polymerexhibiting both a glass transition temperature (Tg) and a melting isotherm(Tm), as evidenced in the DSC thermogram. Thermal properties of the compositemembranes were significantly enhanced. Both, the decomposition temperature andthe residual weight increased when compared with dense PVA membranes. Thechemically crosslinked PVA with maleic acid resulted in the formation ofcomposite membranes with improved pervaporation properties for separation application.Keywords: Composite membranes, polymers,synthesis, characterization, hydrophilicity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238586,"idioma_id":4,"titulo":"Structural and magnetic properties of nanocrystalline Bi1-xLaxFeO3 (0.0&nbsp;&le;&nbsp;x&nbsp;&le;&nbsp;0.4) synthesized by a mechanochemical route","resumen":"Bi1-xLaxFeO3 (0.0 &#8804; x &#8804; 0.4) powders were prepared by means of a solid acid-base reaction induced by mechanochemical energy. Bi, La and Fe chlorides were high-energy ball-milled with NaOH, yielding a mixture of Bi1-xLaxFeO3 and NaCl. After heating and washing, nanoparticles of Bi1-xLaxFeO3 were obtained as a main product, with low contents of secondary phases. Structural characterization was performed by X-ray diffraction (Rietveld refinement) and Raman spectroscopy. The hyperfine magnetic behavior was analyzed by means of Mössbauer spectroscopy and the microstructure of the particles was evaluated by transmission electron microscopy. Differential scanning calorimetry was employed to investigate the thermal behavior of the samples and magnetic measurements at room temperature were also carried out. Crystal structure transitions as a function of composition were identified. Moreover, an intricate magnetic behavior was observed, which was explained on the basis of the concomitant contribution of two different canting levels of the antiparallel spins.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238588,"idioma_id":4,"titulo":"Identification of residual stresses in multi-layered arterial wall tissues using a variational framework","resumen":"In the past decades a considerable amount of literature has been published addressing the study of the mechanical behavior of arterial walls. Ex-vivo experimentation made possible the development of constitutive models and the characterization of material parameters contributing to the understanding of the mechanobiological response of vascular tissues. Moreover, the existence of residual stresses in configurations free of load was revealed, and its impact in the general stress state of the tissue was quantified. In recent years, data assimilation techniques have seen a rapid development in cardiovascular modeling field, primarily focusing on the estimation of material parameters for arterial wall segments using information provided by medical imaging as well as by in-vitro settings. However, concerning the estimation of residual stresses, this research field is in its early stages, and much work is still required for the full functional characterization of arterial tissues. In this context, a conceptual variational framework for the development of residual stress estimation tools is proposed. Particularly, a variational formulation for the characterization of residual deformations and the associated stresses in arterial walls, based on full displacement field measurements of the vessel, is presented. Considering as known data the material parameters characterizing the behavior of the tissue and a set of arterial wall configurations at equilibrium with well defined pressure loads, we propose a cost functional that measures the mechanical imbalance caused by the lack of knowledge of residual stresses. In this manner, the characterization of residual stresses becomes a problem of minimizing such cost functional. Three numerical examples are presented highlighting the potential of the proposed approach. Among these examples, the characterization of residual stresses in a cylindrical geometry representing a three-layered aorta artery is performed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238589,"idioma_id":4,"titulo":"Chemotaxis detection towards chlorophenols using video processing analysis","resumen":"the metabolic pathways and degradationof CPs have been studied in bacteria and the genes and enzymesinvolved have been identified and characterized (Alva andPeyton, 2003; Arora and Bae, 2014; Bonfá et al., 2013; Haddadi andShavandi, 2013; Quilty, 1998; Wang et al., 2014). In spite of this, to ourknowledge, there are few communications about chemotaxis towardsphenolic compounds (Arora et al., 2015; Bhushan et al., 2000; Paulet al., 2006; Pham and Parkinson, 2011; Sarand et al., 2008). However,these studies have not included chlorophenols. Therefore, the mainobjective of this study was to characterize the chemotactic responsetowards CPs by a mixed culture composed of Pseudomonas aeruginosaand Achromobacter marplatensis. We were able to determine this responseusing the new method of video processing analysis recentlypublished by our group (Nisenbaum et al., 2016) and develop a newtool to determine the mean velocity of the response.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238590,"idioma_id":4,"titulo":"Acute treatment with copoazú fermented extract ameliorates myocardial ischemia-reperfusion injury via eNOS activation","resumen":"Our aim was to examine the effects of aqueous extracts of fermented (CFE) and non-fermented (CNFE) ¨copoazú¨ (fruit of Theobroma grandiflorum) seeds against ischemia-reperfusion injury. Isolated rat hearts were submitted to 30 min of global ischemia (GI) and 60 min of reperfusion (R). Other hearts received CFE or CNFE in absence or in presence of L-NAME (a nitric oxide synthase inhibitor). Infarct size (IS) and post-ischemic myocardial function (PMF) were measured. Lipid peroxidation, reduced glutathione (GSH) and the expression of phosphorylated forms of eNOS, Akt, GSK-3&#946; and PKC&#949; were assessed. The response of isolated mitochondria to Ca2+ (MR) was also determined. CFE but not CNFE decreased IS, increased PMF and the expression of P-eNOS, P-Akt, P-GSK-3&#946; and P-PKC&#949;, partially preserved GSH and improved MR. These effects were lost in presence of L-NAME. These data demonstrate that the acute treatment with CFE protects the heart against ischemia-reperfusion damage through NOS-dependent mechanisms.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238591,"idioma_id":4,"titulo":"Abstracts","resumen":"Summary: Since ancient times, man has used medicinal plants for the prevention and treatment of various diseases. Despite their beneficial and traditional role in different communities, it must be taken into consideration that they can also cause adverse reactions and toxicity. The aim of this study was to analyze the reports on Communication of Adverse Events for the use of Herbal Medicines, Plant Products and\/or Preparations of Vegetable Drugs, received as Chaco?s Peripheral Reporter for the National Pharmacovigilance System, part of the National Administration of Drugs, Food and Medical Technology (ANMAT) of Argentina during the 2010?2016 period. A retrospective analysis of the reports received from pharmacies and health centers was made using the Anatomical, Therapeutic, Chemical (ATC) classification guide for herbs. The causality was assessed by the Naranjo et al. algorithm and the severity was classified into three categories: mild, moderate, and severe. From the total of notifications received (n = 135), 80% involved the use of a single plant product, 15% the mixture of two or more and 5% the use of herbal medicines. Thirtyfour percent of reports about adverse reactions involved children, while female sex prevailed over male. According to the ATC classification of herbs, 71% corresponded to the HA group (alimentary tract and metabolism) as the most reported, followed by 14% to the HN group (nervous system) and the rest to other groups. The most common adverse reactions proved to be probables and milds. The most frequently reported medicinal plants involving children were Chenopodium ambrosioides L. and Illicium verum Hook. F., with severe adverse effects such as seizures being described, whereas in the adult population it was Cassia angustifolia Vahl., with moderate adverse effects. It is essential to monitor and identify the risks posed by plants, especially when used by vulnerable populations, thereby promoting their safe use.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238594,"idioma_id":5,"titulo":"Consumo excesivo episódico de alcohol: cambio natural en estudiantes universitarios","resumen":"El consumo abusivo de alcohol puede ser abandonado sin ayuda formal, sin embargo, la información sobre este hecho es escasa, especialmente en jóvenes que adoptan este tipo de consumo. El objetivo de este estudio es estimar la prevalencia de cambio natural del consumo excesivo episódico de alcohol y explorar su relación con consecuencias adversas del consumo y otras características individuales en jóvenes universitarios. En una muestra aleatoria de 828 estudiantes se evaluó el consumo excesivo episódico pasado\/actual, problemas relacionados con el consumo de alcohol, uso de otras sustancias psicoactivas, género y estado civil. La prevalencia de cambio natural fue de 7%. El cambio en el consumo excesivo episódico implicó menor probabilidad de problemas psíquicos, episodios de amnesia anterógrada, lesiones, consumo de otras sustancias y una mayor probabilidad de estar en pareja. Se discute el rol de la severidad de las consecuencias en el cambio natural del consumo, posibles factores de protección y potenciales intervenciones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238597,"idioma_id":4,"titulo":"Psychometric Properties of Brief Screening Tests for Alcohol Use Disorders during Pregnancy in Argentina","resumen":"Background&#8195;Considering the physical, mental and behavioral problems related to fetal alcohol exposure, prenatal clinical guides suggest a brief evaluation of alcohol consumption during pregnancy to detect alcohol intake and to adjust interventions, if required. Even if any alcohol use should be considered risky during pregnancy, identifying women with alcohol use disorders is important because they could need a more specific intervention than simple advice to abstain. Most screening tests have been developed and validated in male populations and focused on the long-term consequences of heavy alcohol use, so they might be inappropriate to assess consumption in pregnant women. Objective&#8195;To analyze the internal reliability and validity of the alcohol screening instruments Alcohol Use Disorders Identification Test (AUDIT), Alcohol Use Disorders Identification Test - Consumption (AUDIT-C), Tolerance, Worried, Eye-Opener, Amnesia and Cut-Down (TWEAK), Rapid Alcohol Problems Screen - Quantity Frequency (RAPS-QF) and Tolerance, Annoyed, Cut-Down and Eye-Opener (T-ACE) to identify alcohol use disorders in pregnant women. Methods&#8195;A total of 641 puerperal women were personally interviewed during the 48 hours after delivery. The receiver operating characteristics (ROC) curves and the sensitivity and specificity of each instrument using different cut-off points were analyzed. Results&#8195;All instruments showed areas under the ROC curves above 0.80. Larger areas were found for the TWEAK and the AUDIT. The TWEAK, the T-ACE and the AUDIT-C showed higher sensitivity, while the AUDIT and the RAPS-QF showed higher specificity. Reliability (internal consistency) was low for all instruments, improving when optimal cut-off points were used, especially for the AUDIT, the AUDIT-C and the RAPS-QF. Conclusions&#8195;In other cultural contexts, studies have concluded that T-ACE and TWEAK are the best instruments to assess pregnant women. In contrast, our results evidenced the low reliability of those instruments and a better performance of the AUDIT in this population.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238598,"idioma_id":4,"titulo":"Broadening the evidence for the Theory of Planned Behavior: predicting heavy episodic drinking in Argentinean female and male youth","resumen":"Introduction. Although the Theory of Planned Behavior has successfully been applied to explain heavy episodic drinking, recent reviews have identified gaps in the literature like the role of gender and scarce research from non English speaking countries. Objective. We aim to broaden the evidence for the Theory of Planned Behavior by evaluating the capacity of the model to predict heavy episodic drinking in Argentinean female and male youth. Methods. Multiple linear and logistic regressions were performed. Results. Attitude was the main predictor of heavy episodic drinking intention; there were gender differences, among women perceived behavioral control and subjective norm were also predictors of heavy episodic drinking intentions. The intention was the main predictor of heavy episodic drinking for both genders, while perceived behavioral control was also a predictor among women. Conclusions. Theory of Planned Behavior allows us to better understand the motivational variables related to heavy episodic drinking intention and performance, and thus, to design appropriate prevention interventions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238599,"idioma_id":4,"titulo":"Trends in the study of implicit alcohol related cognition","resumen":"According to the dual process model, the interaction between explicit (controlled) and implicit (automatic) cognitions would allow the understanding of irrational actions like addictive behaviors. This model has gained great popularity among addiction researchers, leading to an exponential growth in publications on implicit alcohol related cognition (IAC). Hence, the goal of this article is to identify trends in the study of IAC by means of a bibliometric and content analysis of the empirical studies published up to May, 2013. Throughout this paper, the studied topics of IAC were characterized, the most prolific countries, authors and journals were recognized, the most cited publications were detected and the most employed methods were identified.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238600,"idioma_id":5,"titulo":"Estresores Ambientales, Factores Socioeconómicos, y Problemas por Uso de Alcohol en Universitarios de Argentina","resumen":"Antecedentes: La relación entre el consumo de alcohol, otras características individuales y los problemas relacionados con ese consumo podrían variar según características ambientales en ciertas poblaciones. Objetivo: Determinar si existe una relación jerárquica según la exposición a estresores medioambientales (pobreza y violencia del vecindario), entre ciertas características sociodemográficas individuales (el nivel socio económico, edad, género), el consumo habitual de alcohol y otras sustancias psicoactivas y los problemas por uso de alcohol en estudiantes universitarios argentinos. Método: El diseño fue correlacional, la muestra aleatoria (N=1578, 58% mujeres), y se efectuó un modelaje multinivel. Se evaluaron: problemas por consumo de alcohol, como efectos fijos el consumo habitual de alcohol (cantidad\/frecuencia), y de otras sustancias psicoactivas, factores sociodemográficos (nivel socioeconómico, edad y género) y como efectos aleatorios estresores ambientales (índice de hacinamiento y de delitos por vecindario). Resultados: El índice de hacinamiento resultó ser el mejor predictor de segundo nivel de los problemas por uso de alcohol. El nivel socioeconómico, el consumo habitual de alcohol, y de otras sustancias psicoactivas, y la edad predijeron directamente (Nivel 1) los problemas por uso de alcohol. El género no resultó ser un predictor directo ni un moderador de las relaciones. Discusión y Conclusiones: Al menos un estresor ambiental (la pobreza del vecindario) se relaciona con la variabilidad observada en los problemas por uso de alcohol. A nivel individual, la cantidad y frecuencia del consumo de alcohol, y el consumo de sustancias psicoactivas fueron los predictores más fuertes de los problemas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238607,"idioma_id":4,"titulo":"Acute treatment with copoaz&uacute; fermented extract ameliorates myocardial ischemia-reperfusion injury via eNOS activation","resumen":"Our aim was to examine the effects of aqueous extracts of fermented (CFE) and non-fermented (CNFE) ¨copoazú¨ (fruit of Theobroma grandiflorum) seeds against ischemia-reperfusion injury. Isolated rat hearts were submitted to 30 min of global ischemia (GI) and 60 min of reperfusion (R). Other hearts received CFE or CNFE in absence or in presence of L-NAME (a nitric oxide synthase inhibitor). Infarct size (IS) and post-ischemic myocardial function (PMF) were measured. Lipid peroxidation, reduced glutathione (GSH) and the expression of phosphorylated forms of eNOS, Akt, GSK-3&#946; and PKC&#949; were assessed. The response of isolated mitochondria to Ca2+ (MR) was also determined. CFE but not CNFE decreased IS, increased PMF and the expression of P-eNOS, P-Akt, P-GSK-3&#946; and P-PKC&#949;, partially preserved GSH and improved MR. These effects were lost in presence of L-NAME. These data demonstrate that the acute treatment with CFE protects the heart against ischemia-reperfusion damage through NOS-dependent mechanisms.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238608,"idioma_id":4,"titulo":"Long range interactions in antiferromagnetic quantum spin chains","resumen":"We study the role of long range dipolar interactions on antiferromagnetic spin chains, from the classical S &#8594; &#8734; limit to the deep quantum case S = 1\/2, including a transverse magnetic field. To this end, we combine different techniques such as classical energy minima, classical Monte Carlo, linear spin waves, bosonization and DMRG. We find a phase transition from the already reported dipolar ferromagnetic region to an antiferromagnetic region for high enough antiferromagnetic ex-change. Thermal and quantum fluctuations destabilize the classical order before reaching magnetic saturation in both phases, and also close to zero field in the antiferromagnetic phase. In the ex-treme quantum limit S = 1\/2, extensive DMRG computations show that the main phases remain present with transition lines to saturation significatively shifted to lower fields, in agreement with the bosonization analysis. The overall picture keeps close analogy with the phase diagram of the anisotropic XXZ spin chain in a transverse field. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238610,"idioma_id":5,"titulo":"PREPARACION DE BIOTEMPLATES PARA LA OBTENCIÓN DE CERÁMICOS POROSOS BIOMIMÉTICOS BASADOS EN SiOC","resumen":"En este trabajo se estudió el desarrollo y caracterización de ´biotemplates´ infiltrados con un precursor cerámico polimérico sintetizado, con vistas a la obtención de cerámicos porosos biomiméticos basados en SiOC. Como ´biotemplates´ se emplearon muestras de álamo, las cuales se caracterizaron por medidas de densidad, porosidad y humedad relativa, y análisis microestructural por SEM. Como agente infiltrante, se empleó un polisilsesquioxano (MP-POSS) de bajo peso molecular con alto contenido de grupos silanoles, el cual se sintetizó por el método sol-gel a partir de la condensación hidrolítica de 3-metacriloxipropil-trimetoxisilano en medio ácido. La caracterización fisicoquímica de este agente se realizó por ATR-FTIR, DSC, medida de densidad picnométrica y comportamiento al flujo en función de la temperatura. La infiltración de ´templates´ nativos y nativos activados físicamentese realizó bajo vacío a temperatura ambiente, 40 y 60°C en un equipo de diseño propio.La activación física de los ´templates´ (extracción de componentes de bajo peso molecular) se realizó en un equipo de extracción Soxhlet empleando una secuencia específica de solventes (acetona, etanol), previamente determinada, con un ciclo de secado específico entre cada ciclo de extracción. Sobre cada tipo de ´template´ (nativo y nativo activado) se realizaron 4 ciclos de infiltración hasta alcanzar una ganancia de peso constante siguiendo un protocolo previamente establecido. Las muestras infiltradas se trataron a 135ºC, 3h para inducir la gelación del agente infiltrante. Los ´templates´ infiltrados y curados se caracterizaron por medidas de ganancia de peso, densidad y porosidad abierta, y análisis microestructural por SEM. Los resultados obtenidos indicaron que los ´templates´ de álamo preparados resultaron adecuados para ser infiltrados con el polisilsesquioxano sintetizado. Este proceso fue notablemente mejorado cuando se utilizaron las muestras con activación física y el agente infiltrante a temperatura ambiente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238617,"idioma_id":5,"titulo":"Investigando la Educación Física con Adultos Mayores en el Programa de Educación Permanente de Adultos Mayores","resumen":"Pensamos la extensión universitaria como objeto de estudio, y por lo tanto, como práctica factible de ser investigada. Nos preguntamos por las estrategias que podrían implementarse para que la investigación esté al servicio de la extensión, siendo ésta la forma de concretar la función social de la Universidad. Sobre todo, nos interesa indagar cuál puede ser el método a seguir para investigar la extensión universitaria; así, consideramos, que la investigación podría pensarse como modo de abordar las problemáticas surgidas en las prácticas de extensión. Las reflexiones que expondremos aquí tienen que ver con nuestro recorrido profesional en proyectos de investigación y con el dictado de talleres de Educación Física con adultos mayores","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238621,"idioma_id":5,"titulo":"Aprendizaje adaptativo: un caso de evaluación personalizada","resumen":"Este artículo presenta la&nbsp; experiencia inicial de aprendizaje adaptativocon estudiantes universitarios, siguiendo los principios de la evaluaciónorientada al aprendizaje. &nbsp;La propuesta considerala personalización de pruebas de autoevaluación, conforme&nbsp; a los estilos de aprendizaje predominantes,en un ambiente virtual de aprendizaje (AVA). Se llevaron a cabo las siguientesactividades: inspección del perfil del estudiante y su base conceptual,definición de las&nbsp; pruebas personalizadasy evaluación de los resultados. El proyecto se desarrolla con un enfoque basadoen procesos para la mejora continua. Los resultados muestran una mejoría en ellogro de los estudiantes y el análisis del proceso orienta a los docentes enlos ajustes del diseño pedagógico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238622,"idioma_id":5,"titulo":"?Los sistemas de evaluación en las propuestas de enseñanza aprendizaje en el marco de la Teoría y Metodología de la Arquitectura","resumen":": El presente trabajo de investigación en docencia fue elaborado en el curso de pos grado: ?El sistema de evaluación en las propuestas de enseñanza aprendizaje en la arquitectura? cuyos lineamientos establecieron la necesidad de diagnosticar, problematizar,  investigar y  proponer  en forma reflexiva y crítica  modelos de  sistemas de evaluación empleados en el proceso de enseñanza aprendizaje en el marco de la materia Teoría del Diseño II: Metodología del Diseño de la Facultad de Arquitectura (UNNE). Se plantearon como ejes de la investigación1)Los instrumentos de evaluación ( modelos)2)Objetivos, estructura y contexto de aplicación de criterios de evaluación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238624,"idioma_id":4,"titulo":"Non-Ionizing Radiation and Spectrum Occupancy Measurement","resumen":"Debido al gran auge del uso de  las telecomunicaciones, y a la lluvia de radiación electromagnética no ionizante que emiten; el estudio del impacto que éstas producen sobre la población es constante. Existen recomendaciones nacionales e internacionales, para verificar el cumplimiento de los límites de emisiones de radiación electromagnética, las formas de medición de las mismas, y maneras de evaluar los resultados. Este proyecto tiene como objetivo analizar el cumplimiento de recomendaciones sobre emisiones de radiaciones no ionizantes con la aplicación de  procedimientos de medición, para bandas de frecuencias de tecnologías de Telefonía Móvil","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238629,"idioma_id":5,"titulo":"Categorización de las concepciones de docentes universitarios de ciencias sobre 'qué se enseña' y 'qué se evalúa'","resumen":"Se indagaron las concepciones sobre la enseñanza de docentes universitarios de carreras científicas desde la perspectiva de las teorías implícitas. Desde un enfoque fenomenográfico, se llevó a cabo un estudio descriptivo con un diseño ex post facto. La variable en estudio fue la concepción sobre la enseñanza analizada en dos dimensiones: qué se enseña y cómo se enseña. Se realizaron entrevistas semiestructuradas a 15 docentes. Se extrajeron categorías de respuestas utilizando el método comparativo constante. Respecto de la dimensión qué se enseña, se pudieron describir cinco categorías que recorren un continuo que va desde la concepción que considera que se deben enseñar contenidos conceptuales exclusivamente, hasta la posición que entiende que se deben enseñar competencias para el cambio conceptual. En la dimensión ?cómo se aprende? se extrajeron cuatro categorías. En esta dimensión, las concepciones varían desde concebir la enseñanza como la actividad que consiste en presentar información clara y precisa hasta las posiciones en las que enseñar requiere poner el foco en el alumno y ayudarlo a aprender. La distribución de frecuencias en las categorías encontradas muestra que en, los docentes entrevistados, predominan las concepciones con una visión de la enseñanza centrada en el profesor y orientada hacia los contenidos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238630,"idioma_id":4,"titulo":"Increased delivery of chemotherapy to the vitreous by inhibition of the blood-retinal barrier.","resumen":"Treatment of retinoblastoma -a pediatric cancer of the developing retina- mightbenefit from strategies to inhibit the blood-retinal barrier (BRB). The potentanticancer agent topotecan is a substrate of efflux transporters BCRP and P-gp,which are expressed at the BRB to restrict vitreous and retinal distribution ofxenobiotics. In this work we have studied vitreous and retinal distribution,tumor accumulation and antitumor activity of topotecan, using pantoprazole asinhibitor of BCRP and P-gp. We used rabbit and mouse eyes as BRB models andpatient-derived xenografts as retinoblastoma models. To validate the rabbit BRBmodel we stained BCRP and P-gp in the retinal vessels. Using intravitreousmicrodialysis we showed that the penetration of the rabbit vitreous by lactonetopotecan increased significantly upon concomitant administration of pantoprazole(P=0.0285). Pantoprazole also increased topotecan penetration of the mousevitreous, measured as the vitreous-to-plasma topotecan concentration ratio at thesteady state (P=0.0246). Pantoprazole increased topotecan antitumor efficacy and intracellular penetration in retinoblastoma in vitro, but did not enhanceintratumor drug distribution and survival in mice bearing the intraocular humantumor HSJD-RBT-2. Anatomical differences with the clinical setting likely limitedour in vivo study, since xenografts were poorly vascularized masses that loadedmost of the vitreous compartment. We conclude that pharmacological modulation of the BRB is feasible, enhances anticancer drug distribution into the vitreous and might have clinical implications in retinoblastoma.CHEMICAL COMPOUNDS INCLUDED INTHIS MANUSCRIPT: Topotecan (PubChem CID: 60700) Pantoprazole sodium (PubChem CID:15008962).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238664,"idioma_id":5,"titulo":"El terrorismo de Estado en noticias. Las operaciones de 'acción psicológica' en Clarín durante los primeros años de la dictadura","resumen":"El objetivo de este artículo es analizar las operaciones de prensa vinculadas a las tareas de acción psicológica de las FFAA publicadas por el diario Clarín durante el período de mayor intensidad represiva (1976-1978). Partimos del supuesto que estas acciones comunicacionales de ocultamiento, montaje y falsificación de la información, elaboradas en forma articulada conlos servicios de inteligencia de las Fuerzas Armadas y de Seguridad, se constituyeron en uno de los modos típicos de la comunicación del terrorismo de Estado en la prensa masiva. Estas publicaciones expresaron el rasgo predominante de la metodología instalada por las Juntas militares, es decir, la articulación contingente entre visibilidad\/ocultamiento, legalidad\/ilegalidad, publicidad\/clandestinidad, a partir de la cual operaron como condición deposibilidad de la violencia masiva estatal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238666,"idioma_id":5,"titulo":"Abelardo Castillo, crónicas editoriales de un estado de sublevación: 1966-1969","resumen":"En una serie de textos editoriales y una crónica publicadas en la revista literaria El Escarabajo de Oro, Abelardo Castillo elabora una voz testimonial del clima político argentino en el final de la década del 60. En 1966 el proyecto editorial dirigido por Castillo alcanza la publicación de treinta números; y al mismo tiempo, se produce la autoproclamada Revolución Argentina que derroca la presidencia de Arturo Illia, acontecimiento que inicia una década de insurrecciones políticas y represión estatal. La línea editorial de la revista se condiciona en respuesta al nuevo momento político. En este panorama, el texto de Castillo dedicado a las protestas en Córdoba durante mayo de 1969 elabora una representación paradigmática del escritor testigo; un cronista posicionado como un ojo que ve y registra críticamente en su escritura la inminencia de un estado de sublevación. La crónica editorial se propone como una indagación que excede las ortodoxias políticas e ideológicas, y en su lugar plantea un recorrido a través de múltiples factores implicados en la fisura de un orden político y social que, en el contexto argentino, se materializa en la dictadura de Onganía.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238667,"idioma_id":5,"titulo":"Capitalismo, lenguaje e ideología a través de Rodolfo Fogwill","resumen":"A través de Rodolfo Fogwill, propongo una lectura en torno a la irrupción de la semiótica como modelo teórico para los estudios sociales. Para esto, considero un artículo crítico en co-autoría con Oscar Steimberg en el cual se despliega un análisis del fenómeno publicitario. En consecuencia, es posible advertir como la renovación implicada por el estructuralismo en el estudio de los medios masivos contribuyó a una evaluación crítica de la cultura. A partir de este panorama inicial, puede dimensionarse el trasfondo del proyecto editorial Tierra Baldía y, simultáneamente, la emergencia literaria de Fogwill hacia 1980.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238668,"idioma_id":5,"titulo":"Estética y política: algunas propuestas novoseculares","resumen":"Propongo la lectura de algunos textos teórico-críticos realizados durante la primera década del siglo XXI con la finalidad de cartografiar la compleja trama del saber estético y, al hacerlo, considerar nuevas flexiones y puntos de vista para leer las artes, la literatura y sus políticas. Las indagaciones Jacques Rancière, Andreas Huyssen, Nicolás Bourriaud, Reinaldo Laddaga y Néstor García Canclini, se proyectan en el escenario contemporáneo como reformulaciones de un discurso que intenta referir el trabajo con la forma y la sensación, ahora diseminado como un tipo producción singular que reorganiza las condiciones materiales y simbólicas del arte en su diálogo con el mundo. Cada uno de estos autores realiza una caracterización singular de la estética contemporánea, todos ellos ponen en entredicho la rigidez disciplinar para identificar a las prácticas estéticas como actos que reorganizan el sentido de la vida en común y la política a través de la exploración con de las formas sensibles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238669,"idioma_id":5,"titulo":"Fogwill en El ojo Mocho, una escena de combate","resumen":"En 1997 Horacio González, Christian Ferrer, Eduardo Rinesi y María Pía López  entrevistaron para la revista El Ojo Mocho a Rodolfo Fogwill. Durante ese extenso diálogo ?publicado en el número 11 de la revista dirigida por González y ahora reeditado en forma íntegra- el entrevistado desplegó su típico arsenal de provocaciones para registrar, con intermitencias digresivas, las variaciones de una memoria intelectual y política compartida, cuyo interlocutor privilegiado era el propio González. En un contrapunto dialógico no desprovisto de provocación, Fogwill recorría los vínculos de su pasado en la carrera de Sociología de la Universidad de Buenos Aires para involucrarse con importantes figuras del campo teórico y la militancia revolucionaria argentina de las décadas del 60 y 70. La entrevista se proponía, en parte, como un salto hacia ese pasado; sin embargo, lejos de un registro minucioso y ordenado, la conversación se expandía siguiendo una lógica derivativa para conducir hacia puntos radicalmente distantes de la realidad argentina. En todo caso, el resultado es un diálogo que puede leerse como una microhistoria de las ideas políticas, las innovaciones recientes de la teoría cultural y las últimas novedades en la literatura argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238670,"idioma_id":4,"titulo":"Modelling of Fluidised Geomaterials: The Case of the Aberfan and the Gypsum Tailings Impoundment Flowslides","resumen":"The choice of a pure cohesive or a pure frictional viscoplastic model to represent the rheological behaviour of a flowslide is of paramount importance in order to obtain accurate results for real cases. The principal goal of the present work is to clarify the influence of the type of viscous model?pure cohesive versus pure frictional?with the numerical reproduction of two different real flowslides that occurred in 1966: the Aberfan flowslide and the Gypsum tailings impoundment flowslide. In the present work, a depth-integrated model based on the v&#8722;pwBiot?Zienkiewicz formulation, enhanced with a diffusion-like equation to account for the pore pressure evolution within the soil mass, is applied to both 1966 cases. For the Aberfan flowslide, a frictional viscous model based on Perzyna viscoplasticity is considered, while a pure cohesive viscous model (Bingham model) is considered for the case of the Gypsum flowslide. The numerical approach followed is the SPH method, which has been enriched by adding a 1D finite difference grid to each SPH node in order to improve the description of the pore water evolution in the propagating mixture. The results obtained by the performed simulations are in agreement with the documentation obtained through the UK National Archive (Aberfan flowslide) and the International Commission of large Dams (Gypsum flowslide)","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238671,"idioma_id":4,"titulo":"A reference state curve to define the state of soils over a wide range of pressures and densities","resumen":"Granular materials exhibit a behavior that is strongly dependent on density, effective confining pressure, and grain characteristics. The complexity is such that in the past, for a given sand, loose and dense specimens, or specimens subjected to very low or very high confining pressures were considered as different materials and were modeled as such, using different constitutive parameters. The introduction of the state parameter improved both understanding the behavior and modeling of granular materials. Several alternative definitions have been proposed for state parameter but they suffer from some limitations, especially when sand is very loose, has fines, or is subjected to high confining pressures. The purpose of this paper is to describe those deficiencies and to introduce a new state index based on a novel reference state curve. The proposed reference state curve is then applied to understanding and predicting some important aspects of soil behavior such as: (i) stress ratios at the peak point of undrained effective stress paths, (ii) the 'reverse behavior' of sandy soils that show an unusual behavior in undrained shearing under high effective confining pressure.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238675,"idioma_id":4,"titulo":"Knowledge extraction from artificial neural networks (ANN) trained to estimate daily reference evapotranspiration in southeastern of rolling pampas of Argentina.","resumen":"Evapotranspiration is an important component of hydrologic balance and represent essential information for irrigation scheduling and water resources planning. Sometimes, the use of the recommended Penman-Monteith method is restricted by the lack of input variables and, therefore, empirical methods become essential. The study aimed: a) to develop and evaluate the performance of models based on artificial neural networks (ANN) to estimate daily values of reference evapotranspiration (ET0PM) with a limited number of input variables and b) to apply methods of knowledge extraction based on connection weights and sensitivity analysis to better understanding of ANN. Daily evapotranspiration values computed following the Penman-Monteith equation (ET0PM), were used as target outputs for the implementation of the ANN. Data of global radiation (Rg), net radiation (Rn) and extraterrestrial radiation (RTA) were alternated in combinations with air temperature (Ta), vapor pressure deficit (DPV) and wind (u) as inputs to networks of type multilayer perceptron. Also, combinations with basis in RTA and minimum and maximum air temperatures (Tmin, Tmax) were tested. The ANN with best performance for each combination of inputs were retained to evaluate the performance based on multi-criteria analysis. According to the results, it can be concluded that it is possible to estimate accurately daily ET0PM values. Air temperature and deficit of pressure vapor were found to be more effective than wind velocity in modelling ET0, whichever the radiation (Rn, Rg or RTA) used as input. A decomposition method based on Garson?s algorithm was applied to quantify the relative importance for each input variable. Sensitivity analysis was also performed to identify relevant inputs and quantify the risk of a certain combination of inputs on target values. The application of complementary procedures in evaluation of ANN models is discussed, paying attention especially on detection of the better predicting variables and analysis of errors.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238676,"idioma_id":5,"titulo":"Control químico de Pythium spp. en plántulas de soja","resumen":"La podredumbre por Pythium en soja puede aparecer desde la germinación de la semilla hasta mediados de la época de crecimiento. Se evaluó la eficacia de control de cuatro fungicidas aplicados en forma preventiva en semillas de soja. Estas se colocaron en bandejas plásticas conteniendo sustrato comercial tindalizado inoculado con Pythium. Se efectuaron dos ensayos: A) A partir de los fungicidas recomendados para esta enfermedad en la Argentina: metalaxil-M y carbendazim+tiram y B) A partir de los fungicidas de amplio uso en Argentina: azoxistrobina y difenoconazol, pero no como curasemillas. Los tratamientos fueron asignados a las unidades experimentales (bandejas) de acuerdo a un diseño completamente aleatorizado con tres repeticiones por tratamiento. A los 21 días se evaluó la incidencia de la enfermedad por bandeja y se calculó el porcentaje de control de cada fungicida. Los resultados obtenidos se analizaron mediante un Análisis de Varianza y las medias fueron comparadas aplicando el Test DGC con un nivel de significancia del 5%. Metalaxil presentó aproximadamente un 100% de control mientras que para carbendazim+tiram fue solo del 4,30%. La aplicación tanto de azoxistrobina como de difenoconazol difirió significativamente de la de metalaxil con un control de 61% y 28,80% respectivamente. El control químico de la podredumbre por Pythium en plántulas de soja fue más eficaz con la aplicación del fungicida metalaxil de manera preventiva con respecto a los otros tres fungicidas probados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238679,"idioma_id":4,"titulo":"Trends in the study of implicit alcohol related cognition","resumen":"According to the dual process model, the interaction between explicit (controlled) and implicit (automatic) cognitions would allow the understanding of irrational actions like addictive behaviors. This model has gained great popularity among addiction researchers, leading to an exponential growth in publications on implicit alcohol related cognition (IAC). Hence, the goal of this article is to identify trends in the study of IAC by means of a bibliometric and content analysis of the empirical studies published up to May, 2013. Throughout this paper, the studied topics of IAC were characterized, the most prolific countries, authors and journals were recognized, the most cited publications were detected and the most employed methods were identified","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238680,"idioma_id":4,"titulo":"BROADENING THE EVIDENCE FOR THE THEORY OF PLANNED BEHAVIOR: PREDICTING HEAVY EPISODIC DRINKING IN ARGENTINEAN FEMALE AND MALE YOUTH","resumen":"Introduction. Although the Theory of Planned Behaviorhas successfully been applied to explain heavy episodicdrinking, recent reviews have identified gaps in theliterature like the role of gender and scarce research fromnon English speaking countries. Objective. We aim tobroaden the evidence for the Theory of Planned Behaviorby evaluating the capacity of the model to predict heavyepisodic drinking in Argentinean female and male youth.Methods. Multiple linear and logistic regressions wereperformed. Results. Attitude was the main predictor ofheavy episodic drinking intention; there were genderdifferences, among women perceived behavioral controland subjective norm were also predictors of heavyepisodic drinking intentions. The intention was the mainpredictor of heavy episodic drinking for both genders,while perceived behavioral control was also a predictoramong women. Conclusions. Theory of Planned Behaviorallows us to better understand the motivational variablesrelated to heavy episodic drinking intention andperformance, and thus, to design appropriate preventioninterventions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238681,"idioma_id":4,"titulo":"Patients with Primary Immunodeficiencies are a Reservoir for Neurovirulent Vaccine Derived Poliovirus Strains and Represent a Risk to the Polio Eradication Initiative.","resumen":"Immunodeficiency-associated vaccine-derived polioviruses (iVDPVs) have been isolatedfrom primary immunodeficiency (PID) patients exposed to oral poliovirus vaccine(OPV). Patients may excrete poliovirus strains for months or years; the excreted virusesare frequently highly divergent from the parental OPV and have been shown to beas neurovirulent as wild virus. Thus, these patients represent a potential reservoirfor transmission of neurovirulent polioviruses in the post-eradication era. In supportof WHO recommendations to better estimate the prevalence of poliovirus excretersamong PIDs and characterize genetic evolution of these strains, 635 patients including570 with primary antibody deficiencies and 65 combined immunodeficiencies werestudied from 13 OPV-using countries. Two stool samples were collected over 4 days, tested for enterovirus, and the poliovirus positive samples were sequenced. Thirteenpatients (2%) excreted polioviruses, most for less than 2 months following identificationof infection. Five (0.8%) were classified as iVDPVs (only in combined immunodeficienciesand mostly poliovirus serotype 2). Non-polio enteroviruses were detected in 30patients (4.7%). Patients with combined immunodeficiencies had increased risk ofdelayed poliovirus clearance compared to primary antibody deficiencies. Usually, iVDPVwas detected in subjects with combined immunodeficiencies in a short period of timeafter OPV exposure, most for less than 6 months. Surveillance for poliovirus excretionamong PID patients should be reinforced until polio eradication is certified and theuse of OPV is stopped. Survival rates among PID patients are improving in lower andmiddle income countries, and iVDPV excreters are identified more frequently. Antiviralsor enhanced immunotherapies presently in development represent the only potentialmeans to manage the treatment of prolonged excreters and the risk they present to thepolio endgame","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238683,"idioma_id":5,"titulo":"El acceso a la escuela secundaria y el lugar otorgado a la familia en este proceso","resumen":"Un equipo interdisciplinario compuesto por psicólogos, profesores en Ciencias de la Educación y estudiantes de distintas carreras de la Facultad de Humanidades y Ciencias Sociales de la Universidad Nacional de Jujuy, interesados por la problemática de la inclusión educativa en el nivel medio, desarrollamos un proyecto de investigación denominado ?Figuras de soporte que reconocen los adolescentes en momentos de  su transición en el sistema educativo?, radicado en la Secretaria de Ciencia y Técnica de la Universidad Nacional de Jujuy. Transitar por los distintos niveles de escolarización marca, según la literatura científica (Sacristán, 1999) un cambio transcendental en la vida de los estudiantes, que desencadena procesos de múltiples transformaciones psíquicas, cognitivas y en la organización en su vida cotidiana, impactando significativamente en la constitución de su subjetividad y en la construcción de vínculos sociales.     Contamos como objetivo de indagación, conocer las figuras que cobran importancia como orientadores y sostén para los adolescentes, en el ingreso a la escuela secundaria. Desde un enfoque metodológico cualitativo, usamos como estrategias de recolección de información talleres y entrevistas, que se utilizaron en diferentes momentos del proceso, con adolescentes que finalizaron el séptimo grado, en una escuela primaria urbana.A partir de los decires de los estudiantes pudimos visualizar en el ámbito familiar, figuras de soporte de distinta naturaleza y profundidad: económica, afectiva, académica; asimismo en relación al mundo institucional escolar encontramos adultos que constituyen figuras de soporte favorables al sostenimiento en la escuela de los estudiantes y otros que resultan expulsivos del sistema educativo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238690,"idioma_id":4,"titulo":"Identification of residual stresses in multi-layered arterial wall tissues using a variational framework","resumen":"In the past decades a considerable amount of literature has been published addressing the study of the mechanical behavior of arterial walls. Ex-vivo experimentation made possible the development of constitutive models and the characterization of material parameters contributing to the understanding of the mechanobiological response of vascular tissues. Moreover, the existence of residual stresses in configurations free of load was revealed, and its impact in the general stress state of the tissue was quantified. In recent years, data assimilation techniques have seen a rapid development in cardiovascular modeling field, primarily focusing on the estimation of material parameters for arterial wall segments using information provided by medical imaging as well as by in-vitro settings. However, concerning the estimation of residual stresses, this research field is in its early stages, and much work is still required for the full functional characterization of arterial tissues. In this context, a conceptual variational framework for the development of residual stress estimation tools is proposed. Particularly, a variational formulation for the characterization of residual deformations and the associated stresses in arterial walls, based on full displacement field measurements of the vessel, is presented. Considering as known data the material parameters characterizing the behavior of the tissue and a set of arterial wall configurations at equilibrium with well defined pressure loads, we propose a cost functional that measures the mechanical imbalance caused by the lack of knowledge of residual stresses. In this manner, the characterization of residual stresses becomes a problem of minimizing such cost functional. Three numerical examples are presented highlighting the potential of the proposed approach. Among these examples, the characterization of residual stresses in a cylindrical geometry representing a three-layered aorta artery is performed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238691,"idioma_id":5,"titulo":"La tecnología y el arte en los análisis marcuseanos de la racionalidad social","resumen":"P { margin-bottom: 0.21cm; direction: ltr; color: rgb(0, 0, 0); }P.western { font-family: 'Times New Roman',serif; font-size: 12pt; }P.cjk { font-family: 'Times New Roman',serif; font-size: 12pt; }P.ctl { font-family: 'Times New Roman',serif; font-size: 12pt; }El presente trabajo propone comprender la teoría de Marcuse sobre el arte y la tecnología como parte de su teoría de la racionalidad social. En ese marco, las lógicas de la tecnología y del arte aparecen como modos opuestos de configurar esa racionalidad, a la vez que como medios de dominación o emancipación, respectivamente.Mientras que la lógica tecnológica da lugar a la pérdida del poder de negación y a la tesis marcuseana del hombre unidimensional, la experiencia estética vinculada al arte restaura una racionalidad ampliada que, al incluir el orden de la sensibilidad, habilita una posibilidad para el cambio social. (El artículo se encuentra en proceso de evaluación).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238697,"idioma_id":5,"titulo":"Regreso al español: La traducción de Drown de Junot Díaz. Entrevista a Eduardo Lago","resumen":"En 1996, Junot Díaz publicó su primer libro, Drown (New York: Riverhead Books, 1996), que compila varios relatos que habían aparecido en prestigiosas revistas estadounidenses En el mismo año, se gestaban sus traducciones al español: la de Miguel Martínez-Lage y la del escritor, crítico, y traductor Eduardo Lago. En esta entrevista, Lago recuerda el proceso de traducción del libro de Díaz, los retos particulares de traducir la prosa de este escritor y la importancia de la lengua en la literatura de los escritores latinos contemporáneos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238699,"idioma_id":5,"titulo":"Call it my revenge on English: ?Negocios? de Junot Díaz y sus traducciones disonantes","resumen":"El cambio de código o, como él lo denomina él, la ?simultaneidad lingüística?, caracteriza la prosa de Junot Díaz. Inserta palabras y frases en español en textos escritos predominantemente en inglés sin destacarlas tipográficamente ni proveer traducciones para el lector que no comprende ese idioma y, de este modo, crea tensión entre lenguas en su obra narrativa. Esta característica es central en el proyecto literario de Díaz. El objetivo de este trabajo es analizar en qué medida esa tensión típica del de su lenguaje de Díaz se observa en las traducciones a otros idiomas. Un análisis comparativo de traducciones al francés, al portugués y dos traducciones al español del cuento ?Negocios?, publicado en Drown, revela que las traducciones al francés y al portugués recrean en mayor medida la tensión entre lenguas que las versiones en español.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238700,"idioma_id":5,"titulo":"El hábito de movimiento: la poesía bicultural de Judith Ortiz Cofer","resumen":"Judith Ortiz Cofer es una de las escritoras latinas contemporáneas más laureadas en Estados Unidos. Con el fin de profundizar la comprensión de la obra poética de Ortiz Cofer, este artículo explora algunas de sus características centrales, plasmadas de un modo singular en su poema ?The Latin Deli: An Ars Poetica? (1995). Además, mediante la comparación de dos traducciones al español del poema, se analizarán las estrategias empleadas por las traductoras Zulai Marcela Fuentes y Elena Olazagasti-Segovia para transponer este poema bilingüe y bicultural, y los efectos que tienen para el público lector hispanohablante.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238708,"idioma_id":5,"titulo":"Usos del suelo en el sudeste bonaerense: abundancia y composición de las comunidades microbianas","resumen":"Se realizó en recuento e identificación de poblaciones microbianas (bacterias, actinomycetes y hongos)&nbsp; en suelos agrícolas con usos contrastantes (agricultura cotínua, pastizal y monte de acacias). El objetivo fue obtener indicadores biológicos de la calidad de dichos suelos","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238714,"idioma_id":5,"titulo":"Calidad microbiológica de hamburguesas de garbanzo elaboradas en forma artesanal y almacenadas bajo diferentes temperaturas de refrigeración","resumen":"Seanalizó la calidad microbiológica de hamburguesas de garbanzo elaboradas enforma artesanal y almacenadas bajo diferentes temperaturas de refrigeración.Las hamburguesas refrigeradas (4°C) se analizaron cada 72-96 horas durante 21días y las congeladas (-20°C) cada 15 días durante 98 días. Se investigaronBacterias Aerobias Mesófilas Totales (BAMT), Staphylococcus spp. identificando S. aureus, Bacillus cereus,coliformes totales, levaduras y hongos filamentosos con identificación degéneros. En las hamburguesas refrigeradas y congeladas predominaron las BAMT yse detectaron coliformes totales, aunque en ningún caso constituyeronmicroorganismos capaces de ocasionar un riesgo potencial para la salud. No seobservó desarrollo de B. cereus y S. aureus. Estos resultados evidencianque ambas formas de almacenamiento permiten obtener un productomicrobiológicamente inocuo para ser consumido en los períodos de tiempo analizados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238715,"idioma_id":5,"titulo":"Hibridismo y frontera en la literatura marginal contemporánea de Argentina y Brasil","resumen":"Con sus similitudes y diferencias, la emergencia de una literatura marginal contemporánea en Brasil y en Argentina es un fenómeno social que se radica en las denominadas favelas y en los barrios o villas. En ese sentido, sus narrativas describen el contexto social vivido en los barrios periféricos, posibilitando que diversos ?Yoes? queestaban silenciados ?hablen? en un campo literario que era hasta entonces lugar de privilegio y de ?alta cultura?.Dicha literatura es muchas veces interpretada desde una perspectiva legitimista o relativista. Sin embargo, esas claves analíticas impiden identificar las especificidades, las desviaciones y los quiebres narrativos presentes en el emergente campo literario de la literatura marginal, o literatura villera.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238720,"idioma_id":4,"titulo":"A New Species of Opisthodactylus Ameghino 1891 (Aves, Rheidae) from the late Miocene of Northwestern Argentina, with implications for the paleobiogeography and phylogeny of rheas","resumen":"A new species of rheid, Opisthodactylus kirchneri, sp. nov., is erected on the basis of associated elements of both hind limbs from the late Miocene in northwestern Argentina. The new species extends the biochron of Opisthodactylus from early Miocene to late Miocene and its distribution from Patagonia to northwest Argentina. Cladistic analysis recovered an Opisthodactylus-Pterocnemia clade as sister to a Rhea americana clade. The Opisthodactylus-Pterocnemia clade would have inhabited the most southern, central, and western regions of southern South America throughout the early-middle Neogene, whereas the Rhea stock would have had a north-northeastern or Brazilian ancestral distribution in the lowlands of the continent. The similar biogeographic patterns of living and fossil rheids, cariamids, and tinamids seem to roughly reflect the environmental shift from closed to open habitats that took place at the southern end of South America during the Neogene and Pleistocene, and at least in the former two families the effects of isolation produced by the ?Paranaense? sea. Closed-habitat taxa of these three families are recorded at early Miocene localities in Patagonia (O. horacioperezi, O. patagonicus, Noriegavis santacrucensis, and Crypturellus reai), whereas open-habitat taxa come from late Miocene?early Pliocene sites at central (Pterocnemia sp. and Eudromia sp.), northwestern (O. kirchneri and Pterocnemia cf. mesopotamica), and northeastern (Pterocnemia mesopotamica) regions in Argentina. http:\/\/zoobank.org\/urn:lsid:zoobank.org:pub:0BAD0813-31F8-4101-8742-93BDBCABE807 Citation for this article: Noriega, J. I., E. A. Jordan, R. I. Vezzosi, and Juan I. Areta. 2017. A new species of Opisthodactylus Ameghino, 1891 (Aves, Rheidae), from the late Miocene of northwestern Argentina, with implications for the paleobiogeography and phylogeny of rheas. Journal of Vertebrate Paleontology. DOI: 10.1080\/02724634.2017.1278005.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238723,"idioma_id":4,"titulo":"Creep and thermal rounding close to the elastic depinning threshold","resumen":"We study the slow stochastic dynamics near the depinning threshold of an elastic interface in a random medium by solving a particularly suited model of hopping interacting particles that belongs to the quenched-Edwards-Wilkinson depinning universality class. The model allows us to compare the cases of uniformly activated and Arrhenius activated hops. In the former case, the velocity accurately follows a standard scaling law of the force and noise intensity with the analog of the thermal rounding exponent satisfying a modified ?hyperscaling? relation. For the Arrhenius activation, we find, both numerically and analytically, that the standard scaling form fails for any value of the thermal rounding exponent. We propose an alternative scaling incorporating logarithmic corrections that appropriately fits the numerical results. We argue that this anomalous scaling is related to the strong correlation between activated hops that, alternated with deterministic depinning-like avalanches, occur below the depinning threshold. We rationalize the spatiotemporal patterns by making an analogy of the present model in the near-threshold creep regime with some well-known models with extremal dynamics, particularly the Bak-Sneppen model.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238724,"idioma_id":4,"titulo":"Jump Events in a 3D Edwards-Anderson Spin Glass","resumen":"The statistical properties of infrequent particle displacements, greaterthan a certain distance, is known as jump dynamics in the context of structural glassformers. We generalize the concept of jump to the case of a spin glass, by dividingthe system in small boxes, and considering infrequent cooperative spin flips in eachbox. Jumps defined this way share similarities with jumps in structural glasses. Weperform numerical simulations for the 3D Edwards-Anderson model, and study howthe properties of these jumps depend on the waiting time after a quench. Similar to theresults for structural glasses, we find that while jump frequency depends strongly ontime, jump duration and jump length are roughly stationary. At odds with some resultsreported on studies of structural glass formers, at long enough times, the rest timebetween jumps varies as the inverse of jump frequency. We give a possible explanationfor this discrepancy. We also find that our results are qualitatively reproduced by afully-connected trap mode.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238725,"idioma_id":4,"titulo":"HYPOTHYROIDISM DECREASES JAK\/STAT SIGNALING PATHWAY IN LACTATING RAT MAMMARY GLAND THROUGH LACTATION.","resumen":"Thyroid pathologies have deleterious effects on lactation. Especially hypothyroidism (HypoT) induces premature mam-mary involution at the end of lactation and decreases milk production and quality in mid lactation. Milk synthesis is con-trolled by JAK2\/STAT5 signaling pathway and prolactin (PRL), which activates the pathway. In this work we analyzedthe effect of chronic 6-propyl-2- thiouracil (PTU)-induced HypoT on PRL signaling pathway on mammary glands fromrats on lactation (L) days 2, 7 and 14. HypoT decreased prolactin receptor expression, and expression and activation ofStat5a\/b protein. Expression of members of the SOCS-CIS family, inhibitors of the JAK-STAT pathway, decreased in L2and L7, possibly as a compensatory response of the mammary cells to maintain PRL responsiveness. However, on L14,the level of these inhibitors was normal and the transcription of &#945;-lactoalbumin (lalba), a target gene of the PRL pathway,decreased by half. HypoT altered the transcriptional capacity of the cell and decreased mRNA levels of Prlr and Stat5b onL14. Stat5b gene has functional thyroid hormone response elements in the regulatory regions, that bind thyroid hormonereceptor &#946; (TR&#946;) differentially and in a thyroid hormone dependent manner. The overall decrease in the PRL signalingpathway and consequently in target gene (lalba) mRNA transcription explain the profound negative impact of HypoT onmammary function through lactation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238726,"idioma_id":4,"titulo":"Human renal adipose tissue: its influence on renal cell carcinoma","resumen":"We evaluated the effects of conditioned media (CMs) of human adipose tissue from renal cell carcinoma located near the tumor (hRATnT) or farther away from the tumor (hRATfT), on proliferation, adhesion and migration of tumor (786-O and ACHN) and non-tumor (HK-2) human renal epithelial cell lines. Human adipose tissues were obtained from patients with renal cell carcinoma (RCC) and CMs from hRATnT and hRATfT incubation. Proliferation, adhesion and migration were quantified in 786-O, ACHN and HK-2 cell lines incubated with hRATnT-, hRATfT- or control-CMs. We evaluated versican, adiponectin and leptin expression in CMs from hRATnT and hRATfT. We evaluated AdipoR1\/2, ObR, pERK, pAkt y pPI3K expression on cell lines incubated with CMs. No differences in proliferation of cell lines was found after 24 h of treatment with CMs. All cell lines showed a significant decrease in cell adhesion and increase in cell migration after incubation with hRATnT-CMs vs. hRATfT- or control-CMs. hRATnT-CMs showed increased levels of versican and leptin, compared to hRATfT-CMs. AdipoR2 in 786-O and ACHN cells decreased significantly after incubation with hRATfT- and hRATnT-CMs vs. control-CMs. We observed a decrease in the expression of pAkt in HK-2, 786-O and ACHN incubated with hRATnT-CMs. This result could partially explain the observed changes in migration and cell adhesion.We conclude that hRATnT released factors, such as leptin and versican, could enhance the invasive potential of renal epithelial cell lines and could modulate the progression of the disease.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238729,"idioma_id":5,"titulo":"Reflexiones sobre la economía verde. El New Deal Ecológico Mundial","resumen":"En las últimas décadas, el crecimiento económico, el desarrollo industrial y las modernas tecnologíashan aportado un nuevo grado de confort y bienestar a nuestra vida ocasionando un aumentodel consumo de bienes y servicios. Sin embargo, este crecimiento económico se logró a expensasdel agotamiento de los recursos naturales, permitiendo la pérdida generalizada de los ecosistemase ignorando a muchas personas que además de vivir en condiciones de pobreza dependendirectamente de ellos. Algunas de las predicciones de lo que ocurrirá en este siglo XXI apuntana un crecimiento de la población de hasta 9 700 millones en 2050; igualmente se incrementaráel consumo per cápita, la pobreza, la desigualdad social, la degradación o el uso insostenible delos ecosistemas, y se acelerará el cambio climático. Por tanto, el mayor desafío en la actualidadconsiste en conjugar los aspectos económicos, sociales y ambientales de las actividades humanas,tratar de progresar sin destruir el ambiente. El presente trabajo aborda la problemática actual yanaliza un modelo económico alternativo denominado economía verde, sus características, mitosy realidades, y ejemplifica algunas prácticas destacables a nivel mundial para finalizar con lasinnovaciones en la temática desarrolladas particularmente en Argentina, tanto a nivel nacionalcomo provincial. La metodología utilizada se organizó a partir de los ámbitos de análisis ambiental,social, económico e internacional, y consistió en el relevamiento de la bibliografía existentesobre el tema, elaboración y clasificación de conceptos teórico-técnicos específicos, recolecciónde información en fuentes secundarias e identificación de la normativa internacional, regional ynacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238733,"idioma_id":5,"titulo":"Diversidad del género Luticola D. G. Mann (Bacillariophyceae) en sedimentos holocénicos de la Puna jujeña","resumen":"En el marco de las investigaciones paleoambientales que estamos desarrollando en la localidad de Barrancas (23° 18? 08,7? S; 66° 05? 15,2? O; 3666 m snm) detectamos, en sedimentos de los últimos 11.000 años, una alta diversidad y frecuencia de representantes del genero Luticola. Se identificaron 10 especies, de las cuales dos son nuevas (Luticola punae sp. nov. y Luticola juliae sp. nov.). Se describen dos morfotipos de Luticola mollis. Dos de estas especies se citan por primera vez para Argentina y una para Sudamérica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238734,"idioma_id":5,"titulo":"Las infraestructuras ferroviarias en la historia del territorio: proyectos y realizaciones en la Patagonia norte argentina en la primera mitad del siglo XX","resumen":"La Patagonia norte, a pesar de constituir un territorio con recursos hídricos y energéticos, con variadas posibilidades productivas ?agrícolas y ganaderas, forestales e industriales? y bellezas naturales y paisajísticas, continúa a inicios del siglo XX casi deshabitado y prácticamente desconocido. Es así que a lo largo del siglo pasado, este territorio ha sido objeto de múltiples consideraciones de diverso tipo, concentrando un proceso histórico en donde las infraestructuras tuvieron un rol determinante.Basados en la hipótesis general de que las infraestructuras territoriales y los procesos técnicos se vinculan a matrices conceptuales que van más allá de lo estrictamente técnico, entendemos que la historia de los proyectos, realizaciones y estudios para la provisión de distintas infraestructuras debe ser realizada desde un enfoque eslabonado que incluya las dimensiones de lo cultural y lo social, además de los habituales enfoques políticos y económicos. El examen de los proyectos para la Patagonia norte ofrece oportunidades para ensayar el enfoque propuesto, además de aportar al conocimiento de la construcción del territorio norpatagónico como ámbito productivo y región de turismo nacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238737,"idioma_id":4,"titulo":"Seasonal variation of peracarid assemblages in natural and artificial marine environments of the Southwestern Atlantic Ocean","resumen":"The diversity and seasonal variations of two assemblages of marine benthic peracarids were studied between a natural rocky shore and an artificial harbour area across a 12-months period. Samples were obtained monthly in La Estafeta, a rocky intertidal with low human impact, and Mar del Plata Harbour, a polluted environment, between March 2011 and March 2012. Both sites differed markedly in the composition and abundance of species across all seasons: the tanaid Tanais dulongii was most abundant in La Estafeta rocky shore, followed by the amphipods Monocorophium acherusicum, Hyale grandicornis, Ampithoe valida, the isopod Idotea balthica, the tanaid Leptochelia sp. and the isopod Sphaeroma serratum. In contrast, M. acherusicum was most abundant in the harbour area, followed by T. dulongii, S. serratum, Ericthonius punctatus, I. balthica, Caprella equilibra and C. dilatata. Total density of peracarids varied among months in La Estafeta rocky shore and Mar del Plata Harbour. In La Estafeta rocky shore mean density increased from March to May 2011 (autumn in the southern hemisphere; ca. 45,000 ind\/m2), decreased sharply until August and then increased in January 2012. In Mar del Plata Harbour the mean density was lower from March to October (ca. 500,000 ind\/m3), then increased and reached a maximum in January 2012 (more than 1,500,000 ind\/m3), and decreased until the following March. This study suggests that the differences in peracarid assemblages, diversity and seasonally could be related to an effect of temperature, but it should not be discarded a synergistic effect of other factors, such as pollution, food availability and hydrodynamic factors.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238738,"idioma_id":4,"titulo":"Population dynamics of Caprella dilatata and Caprella equilibra (Peracarida: Amphipoda) in a Southwestern Atlantic harbour","resumen":"We studied the population dynamics and reproductive biology of Caprella dilatata and Caprella equilibra in order to provide the basis for understanding the ecological role of both species in Mar del Plata Harbour. Caprellids and organisms from the fouling community were obtained by sampling in the harbour, monthly from April-2014 to March-2015. Mean density of C. dilatata was homogeneous during the study period (ca. 50?200 ind\/100 g) and reached theirmaximum in May (ca. 650 ind\/100 g), while C. equilibra did not show any  differences during the sampling period (ca. 30 ind\/100 g). Juveniles of C. dilatata reached their highest densities in May, while ovigerous females were at their maximum values in late spring, summer and early autumn, and no correlation was found between seawater temperature and monthly density. On the other hand, C. equilibra reached its maximum juvenile and ovigerous female densities in summer, and showed a positive correlation with seawater temperature. Sex-ratiowas female biased in C. dilatata, but in C. equilibra it was equal among sexes. The number of eggs carried by females was positively correlated to the size in both species. The present study suggests that the population dynamics of C. equilibra are intimately related to seawater temperature, while for C. dilatata no relationship was found. Future studies of ecology and behaviour traits on caprellid species are needed in order to determine the ecological role and the environmental factors that could affect both species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238742,"idioma_id":4,"titulo":"The role of macroinvertebrates for conservation of freshwater systems","resumen":"Freshwater ecosystems are the most threatened ecosystems worldwide. Argentinian-protected areas have been established mainly to protect vertebrates and plants in terrestrial ecosystems. In order to create a comprehensive biodiverse conservation plan, it is crucial to integrate both aquatic and terrestrial systems and to include macroinvertebrates. Here, we address this topic by proposing priority areas of conservation including invertebrates, aquatic ecosystems, and their connectivity and land uses. Location: Northwest of Argentina. We modeled the ecological niches of different taxa of macroinvertebrates such as Coleoptera, Ephemeroptera, Hemiptera, Megaloptera, Lepidoptera, Odonata, Plecoptera, Trichoptera, Acari, and Mollusca. Based on these models, we analyzed the contribution of currently established protected areas in the conservation of the aquatic biodiversity and we propose a spatial prioritization taking into account possible conflict regarding different land uses. Our analysis units were the real watersheds, to which were added longitudinal connectivity up and down the rivers. A total of 132 species were modeled in the priority area analyses. The analysis 1 showed that only an insignificant percentage of the macroinvertebrates distribution is within the protected areas in the North West of Argentina. The analyses 2 and 3 recovered similar values of protection for the macroinvertebrate species. The upper part of Bermejo, Salí-Dulce, San Francisco, and the Upper part of Juramento basins were identified as priority areas of conservation. The aquatic ecosystems need special protection and 10% or even as much as 17% of land conservation is insufficient for species of macroinvertebrates. In turn the protected areas need to combine the aquatic and terrestrial systems and need to include macroinvertebrates as a key group to sustain the biodiversity. In many cases, the land uses are in conflict with the conservation of biodiversity; however, it is possible to apply the connectivity of the watersheds and create multiple-use modules.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238747,"idioma_id":5,"titulo":"DETERMINACIÓN DE LAS CONSTANTES HÍDRICAS DE JUJUY Y SALTA A NIVEL DE ASOCIACIÓN, PARA EL MONITOREO DEL AGUA EN EL SUELO","resumen":"Unas de las principales causas de la variación de los rendimientos de los cultivos, es ladisponibilidad de agua en el suelo. A pesar de la importancia de la humedad del suelo para laestimación de los rendimientos de los cultivos, la determinación fiable de esta variable aescala regional, a través de mediciones puntuales convencionales, es compleja. Lainformación requerida por los modelos de balance hídrico es variable y depende de sucomplejidad. Entre la información necesaria para la modelización del agua en el suelo, estánlas precipitaciones, la evapotranspiración y las constantes hidrológicas. La primera se laobtiene por mediciones de diferentes lugares, la segunda por estimaciones, mientras que al nodisponer de mediciones de humedad del suelo in situ, las constantes hidrológicas del suelo seestiman a partir de datos de sus propiedades físicas. El objetivo del presente trabajo es estimarlas constantes hidrológicas del suelo, correspondiente a las asociaciones de suelos para lasprovincias de Jujuy y Salta. Las constantes hídricas estimadas a nivel de asociación, expresanla gran variación edáfica que presentan los suelos en ambas provincias a las diferentesprofundidades estudiadas (30, 70, 100 cm y profundidad efectiva).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238756,"idioma_id":4,"titulo":"OCULAR PHARMACOLOGY OF CHEMOTHERAPY FOR RETINOBLASTOMA","resumen":"PURPOSE: To review preclinical and clinical pharmacokinetic studies of the three most important chemotherapy drugs used for intraocular retinoblastoma and thecontribution of the reported results to optimize treatment.METHODS: Systemic review of pharmacokinetic studies identified by a literaturesearch at Pubmed using the keywords carboplatin, melphalan, topotecan,intravitreal, ophthalmic artery chemosurgery, pharmacokinetics, andretinoblastoma.RESULTS: A total of 21 studies were reviewed for assessing the preclinical andclinical pharmacokinetics of carboplatin, topotecan, and melphalan delivered byintravenous, periocular, ophthalmic artery, and intravitreal routes. Somepreclinical studies were done before translation to the clinics. Others, despite encouraging preclinical data as reported for periocular topotecan did notcorrelate with clinical use. In addition, as was the case for melphalan afterophthalmic artery chemosurgery and despite nonfavorable preclinical information, some routes of drug delivery are clinically effective. Besides topotecan,complete knowledge of the pharmacokinetics of melphalan and carboplatin is still lacking.CONCLUSION: Pharmacokinetic knowledge of chemotherapy may aid to guideretinoblastoma treatment in favor of safety and efficacy. Nonetheless, resultsobtained in preclinical models should be translated with care to the clinics.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238757,"idioma_id":5,"titulo":"Control de las deformaciones en vigas por acción de cargas externas","resumen":"Enesta ocasión se desarrollará un ejemplo numérico de la verificación de la deformaciónde una viga de hormigón armado por acción de momentos flectores generados porcargas distribuidas, el cual fue adaptado de la referencia [4] según el criterio del Reglamento CIRSOC 201-05 [2] y el método de Branson [1], ambos expuestos en el artículo de la revistaVivienda Nº 661.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238758,"idioma_id":4,"titulo":"Constructing a biodiversity terminological inventory","resumen":"The increasing growth of literature in biodiversity presents challenges to users who need to discover pertinent information in an efficient and timely manner. In response, text mining techniques offer solutions by facilitating the automated discovery of knowledge from large textual data. An important step in text mining is the recognition of concepts via their linguistic realisation, i.e., terms. However, a given concept may be referred to in text using various synonyms or term variants, making search systems likely to overlook documents mentioning less known variants, which are albeit relevant to a query term. Domain-specific terminological resources, which include term variants, synonyms and related terms, are thus important in supporting semantic search over large textual archives. This article describes the use of text mining methods for the automatic construction of a large-scale biodiversity term inventory. The inventory consists of names of species, amongst which naming variations are prevalent. We apply a number of distributional semantic techniques on all of the titles in the Biodiversity Heritage Library, to compute semantic similarity between species names and support the automated construction of the resource. With the construction of our biodiversity term inventory, we demonstrate that distributional semantic models are able to identify semantically similar names that are not yet recorded in existing taxonomies. Such methods can thus be used to update existing taxonomies semi-automatically by deriving semantically related taxonomic names from a text corpus and allowing expert curators to validate them. We also evaluate our inventory as a means to improve search by facilitating automatic query expansion. Specifically, we developed a visual search interface that suggests semantically related species names, which are available in our inventory but not always in other repositories, to incorporate into the search query. An assessment of the interface by domain experts reveals that our query expansion based on related names is useful for increasing the number of relevant documents retrieved. Its exploitation can benefit both users and developers of search engines and text mining applications.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238761,"idioma_id":5,"titulo":"Bulbosas de primavera","resumen":"Existe un millar de hermosas especies bulbosas repartidas por el mundo. Debido a esto, el cultivo de plantas bulbosas o bulbicultura constituye una de las ramas más amplias dentro de la jardinería y la floricultura. Como heraldos de la primavera, las bulbosas de floración primaveral tienen la capacidad de transformar jardines aletargados y tristes balcones en fiestas de color. Sus vistosas y bellas flores aparecen durante unos pocos días y una vez en cada temporada, volviendo a estas plantas aún más preciadas. Para su cultivo es necesario conocer la biología, los atributos de valor ornamental y características de manejo. Este artículo provee dicha información con especial énfasis en la descripción de aquellas especies adaptadas al sureste de la provincia de Buenos Aires.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238762,"idioma_id":4,"titulo":"Chromosome numbers, meiotic abnormalities, and 2n pollen formation in accessions of the wild species Chrysolaena Flexuosa (Sims) H. Rob. (Vernonieae, Compositae) from its distribution range in Argentina","resumen":"Chrysolaena flexuosa is a South American species of potential ornamental value (basic chromosome number of x=10). Diploid (n=10) and tetraploid (n=20) cytotypes have been reported for its distribution area although one hexaploid (n=30-32ca.) cytotype has been reported for its most southern distribution. To investigate if ploidy and latitude are positively related in Ch. flexuosa natural populations and if sexual polyploidization could have had a role in the origin of the polyploid cytotypes, we determined chromosome numbers, DNA content, and pollen viability and size and analyzed microsporogenesis in samples of seven Argentinian accessions. Two of the northeastern accessions were diploid and one was tetraploid, whereas the four southeastern accessions were hexaploid. Ploidy levels determined both by chromosome countings and flow cytometry coincided, although monoploid genome size significantly decreased with increasing ploidy. In all accessions, variability was observed for pollen viability and size, as well as for large (presumably 2n) pollen production. This variability was underlined by abnormal meiotic events (lagging chromosomes, parallel spindles, triads at the tetrad stage). The results would indicate that there is, apparently, a positive relation between ploidy and latitude, and suggest a likely role of sexual polyploidization in the origin, establishment and expansion of Ch. flexuosa populations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238763,"idioma_id":4,"titulo":"Survey of the vascular plants of Sierra Chica, the intangible area of the Paititi Natural Reserve (Southeast of the Tandilia Mountain Range System, Buenos Aires Province, Argentina)","resumen":"The Paititi Natural Reserve is located in the Southeastern Mountain Range System of Tandilia (Buenos Aires Province, Argentina). With the aim of establishing the floristic richness of the Sierra Chica -intangible area of the Reserve-, all the vascular plants were inventoried and categorized by family, status and life form. The specific richness was 364 taxa from 72 families, being the most predominant families Poaceae (20.7%), Asteraceae (20.1%) and Fabaceae (5.8%). We found 95 adventive species, 4 cosmopolitan and 264 native. The most abundant life forms were hemicryptophytes (33.1%), therophytes (30.6%), and criptophytes (22.6%); the therophytes being mostly represented by adventive species. We also found species that were described in the Buenos Aires Province but not in mountain range areas. Despite occupying a small area from Argentina, Sierra Chica constitutes a valuable refuge for native flora from the Tandilia System that is presently in danger of being affected by exotic plants.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238764,"idioma_id":5,"titulo":"Calidad de la cama de pollo fresca y del producto final del compostaje","resumen":"El uso de la cama de pollo fresca como fertilizante orgánico es una práctica común  en la actividad  hortícola, habiéndose reportado beneficios como efectos negativos en aplicaciones a largo plazo. Una alternativa para minimizar estos últimos es aplicar el compost de la cama de pollo. En el presente estudio se evaluó las características físico-químicas de la cama de pollo fresca, así como los cambios que sufren las mismas después del proceso de compostaje. Con este fin, se dispuso de material fresco de cama de pollo con el cual se construyeron pilas de compostaje bajo dos manejos distintos: pilas estáticas y sin riego (PE), y pilas con remoción y riegos periódicos (PR). En la cama de pollo fresca como la en la proveniente de las PE y PR se determinó carbono total (CT), pH, conductividad eléctrica (CE), fósforo (PT) y nitrógeno total (NT), nitrato (NO3-), P extraíble, sulfato (SO42-), Ca2+, Mg2+, K+ y elementos traza. La cama de pollo fresca se caracterizó por tener pH levemente alcalino (7,55), CE entre 7,9 y 8,8 dS m-1, alto contenido promedio de CT (354,6 g kg-1), P extraíble (3,32 g P kg-1) y NO3- (5,45 g N kg-1), y menor contenido de K+ (18,92 g kg-1). El compostaje en las PR incrementó (p<0.05) el contenido de PT (19,7 g kg-1) y Mg2+ (5,33 g kg-1) mientras que disminuyó significativamente  (p<0,05) el pH (8,2) y la CE (8,87 dS m-1) en comparación con las PE. En las demás propiedades como CT, P extraíble, NT, NO3-, SO42-, Ca2+, K+, Zn, Cu, Mn, Fe y B no hubo diferencias entre ambos tipo de pilas. La maduración  en las PR fue acompañada por un menor pH y CE, produciendo una mayor reducción de masa y pérdidas por lavado con respeto a las PE. El compostaje empleando la técnica de remoción y riego de las pilas sería una práctica útil para estabilizar los residuos provenientes de aves y minimizar su impacto en el medio ambiente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238768,"idioma_id":4,"titulo":"Rolling contact fatigue behavior of Ti\/TiN coated ADI by cathodic arc deposition","resumen":"This workstudies the rolling contact fatigue (RCF) behavior of austempered ductile ironsamples coated with Ti\/TiN by cathodic arc deposition. The influence of the TiNlayer thickness on the characteristics and RCF life of the coated samples isanalyzed. RCF tests were performed in a flat washer type testing rig, using athrust ball bearing as a counterpart. The maximum contact pressure was 1400MPa. RCF tests results were analyzed using the two-parameter Weibulldistribution. The rolling track of the tested samples was examined by using SEMand EDS.The resultsshow that the surface hardness, residual stresses and coating adhesion strengthof the samples increase as TiN layer thickness increases while surfaceroughness, coating hardness and elastic modulus do not vary significantly withthe TiN layer thickness. Regarding the RCF tests, two failure mechanisms wereobserved in the coated samples, coating delamination and substrate spalling.Coating delamination turned out to be the most predominant mechanism andoccurred at fewer loading cycles than substrate spalling. The EDS analysisrevealed that inside the delaminated areas the Ti interlayer remained adheredto the substrates in all the cases. Extended tests on delaminated samples showgrowing delamination until final failure by substrate spalling occurred. TheWeibull analysis indicates that the RCF life of the coated samples seems tohave a tendency to increase with the TiN layer thickness and, in the case ofthe thicker TiN layer, to exceed the life of uncoated ADI after the extendedtests. However, due to the number of samples employed, the statistic analysisdoes not show significant differences in the RCF behavior of the uncoated andcoated samples.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238769,"idioma_id":5,"titulo":"Un largo y sigiloso camino Espionaje e infiltración policial en el mundo estudiantil en la Argentina. 1957-1972","resumen":"La larga década que recorre el exilio y la vuelta de Perón al poder en Argentina (1955-1973) haciendo foco en el campo estudiantil, permite descubrir un grupo de sujetos que buscaron un espacio de participación política de quienes fueron protagonistas, años más tarde, víctimas del mayor acto de represión estatal durante la dictadura militar de 1976. Durante todo el período estudiado El Departamento de Inteligencia de la Policía de la Provincia de Buenos Aires, (DIPBA) cuya central estaba en la ciudad de La Plata, recibía en forma diaria y detallada un informe que le reportaban los comisarios o agentes de turno locales. Ellos revisaban las noticias del día o se infiltraban en reuniones estudiantiles de cualquier naturaleza, políticas o no, asambleas sindicales, manifestaciones, charlas, conferencias y reuniones en partidos políticos en una lucha sin cuartel jerarquizando a cada uno de ellos según su peligrosidad. Analizar este derrotero sigiloso, desde muy temprano, colabora en comprender finalmente la represión con precisión quirúrgica de los setenta en Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238771,"idioma_id":5,"titulo":"Incidencias sociales y culturales de las políticas de promoción del turismo en áreas rurales en el noroeste argentino","resumen":"Nuestra propuesta tiene como objetivo reflexionar críticamente sobre las distintas políticas de promoción turística que se aplicaron en los últimos años en las provincias de Salta y Jujuy en el NOA, partiendo de nuestras investigaciones en distintos territorios de la región.La unidades consideradas fueron seleccionadas en función de su heterogeneidad productiva, cultural y social, desde los pueblos que viven organizados como comunidades de base étnica en los valles cálidos del este de la Provincia de Salta, hasta espacios donde la propiedad terrateniente se mantuvo desde la época colonial, en base a una fuerte dominación ideológica, como los Valles Calchaquíes.En todos los casos, el despliegue del turismo implica la interpelación a las formas de organización social, a la cultura local y a la manera de pensar la reproducción de los grupos domésticos. Por un lado, genera la expectativa de integración al mundo ?globalizado?, al mismo tiempo que rápidamente se vislumbran las reglas de imposición y concentración de la economía que posiciona a la población local como subordinada.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238772,"idioma_id":4,"titulo":"Mammals and their activity patterns in a forest area in the Humid Chaco, northern Argentina","resumen":"The Humid Chaco has a high mammalian biodiversity. As habitats are threatened due to exploitation and environmental degradation, protected areas can act as refuges for wild animals. In 2006, ca. 1,100 ha of gallery forest were established as the ?Owl Monkey Reserve? within the private cattle ranch ?Estancia Guaycoléc?. The mammalian species richness and composition of the reserve was determined using direct observations, camera traps, and indirect evidence. The camera traps also allowed us to determine the activity periods of 20 of the species. Forty-two species were recorded. A fourth of those species (24%) are categorized under some risk of extinction in Argentina. While most species showed usual activity periods, two species (Mazama americana and Tayassu pecari) were not as exclusively nocturnal as reported from other sites, possibly due to reduced hunting pressure. The presence of various endangered species highlights the importance of protected private reserves.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238773,"idioma_id":4,"titulo":"Rolling contact fatigue behavior of Ti\/TiN coated ADI by cathodic arc deposition","resumen":"This work studies the rolling contact fatigue (RCF) behavior of austempered ductile iron samples coated with Ti\/TiN by cathodic arc deposition. The influence of the TiN layer thickness on the characteristics and RCF life of the coated samples is analyzed. RCF tests were performed in a flat washer type testing rig, using a thrust ball bearing as a counterpart. The maximum contact pressure was 1400 MPa. RCF tests results were analyzed using the two-parameter Weibull distribution. The rolling track of the tested samples was examined by using SEM and EDS. The results show that the surface hardness, residual stresses and coating adhesion strength of the samples increase as TiN layer thickness increases while surface roughness, coating hardness and elastic modulus does not vary significantly with the TiN layer thickness. Regarding the RCF tests, two failure mechanisms were observed in the coated samples, coating delamination and substrate spalling. Coating delamination turned out to be the most predominant mechanism and occurred at fewer loading cycles than substrate spalling. The EDS analysis revealed that inside the delaminated areas the Ti interlayer remained adhered to the substrates in all the cases. Extended tests on delaminated samples show growing delamination until final failure by substrate spalling occurred. The Weibull analysis indicates that the RCF life of the coated samples seems to have a tendency to increase with the TiN layer thickness and, in the case of the thicker TiN layer, to exceed the life of uncoated ADI after the extended tests. However, due to the number of samples employed, the statistic analysis does not show significant differences in the RCF behavior of the uncoated and coated samples.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238774,"idioma_id":4,"titulo":"Experimental assessment of thermal grain boundary embrittlement after tubeplate failure in a petrochemical heat exchanger","resumen":"The analysis of multiple cracks in a heat exchanger tubeplate at a petrochemical plant led to experimental replication of in-service damage. High lifting stresses created a &#64257;rst leak that was repaired.Extendedbranchedintergranularcrackingdevelopedfromthetubeplatesurfacearound the repair weld after few weeks of renewed operation. Chemical analyses failed to detect Na on crack surfaces, while operative conditions also allowed discarding a typical SCC cracking mechanism. Lack of radial interference between tubes and plate, lack of penetration and lack of fusion at tube to tubeplate weld roots were also thought as contributors to cracking. Microstructural analyses revealed martensite clusters in welds and HAZ, and austenite grain boundary precipitates in the tubeplate base material. Thermal cycles were applied to ex-service samples to replicate the conditions for these brittle micro constituents, which were found to be unstable at operating temperatures. Mechanical testing also replicated grain boundary weakness. This inadequate structure was related to welding without proper thermal cycles and heat treatments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238775,"idioma_id":4,"titulo":"Experimental assessment of thermal grain boundary embrittlement after tubeplate failure in a petrochemical heat exchanger","resumen":"The analysis of multiple cracks in a heat exchanger tubeplate at a petrochemical plant led to experimental replication of in-service damage. High lifting stresses created a first leak that was repaired. Extended branched intergranular cracking developed from the tubeplate surface around the repair weld after few weeks of renewed operation. Chemical analyses failed to detect Na on crack surfaces, while operative conditions also allowed discarding a typical SCC cracking mechanism. Lack of radial interference between tubes and plate, lack of penetration and lack of fusion at tube to tubeplate weld roots were also thought as contributors to cracking. Microstructural analyses revealed martensite clusters in welds and HAZ, and austenite grain boundary precipitates in the tubeplate base material. Thermal cycles were applied to ex-service samples to replicate the conditions for these brittle micro constituents, which were found to be unstable at operating temperatures. Mechanical testing also replicated grain boundary weakness. This inadequate structure was related to welding without proper thermal cycles and heat treatments","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238779,"idioma_id":4,"titulo":"Discriminative methods based on sparse representations of pulse oximetry signals for sleep apnea-hypopnea detection","resumen":"The obstructive sleep apnea-hypopnea (OSAH) syndrome is a very common and generally undiagnosed sleep disorder. It is caused by repeated events of partial or total obstruction of the upper airway while sleeping. This work introduces two novel approaches called most dicriminative activation selection (MDAS) and most discriminative column selection (MDCS) for the detection of apnea-hypopnea events using only pulse oximetry signals. These approaches use discriminative information of sparse representations of the signals to detect apnea-hypopnea events. Complete (CD) and overcomplete (OD) dictionaries, and three different strategies (FULL sparse representation, MDAS, and MDCS), are considered. Thus, six methods (FULL-OD, MDAS-OD, MDCS-OD, FULL-CD, MDAS-CD, and MDCS-CD) emerge. It is shown that MDCS-OD outperforms all the others methods. A receiver operating characteristic (ROC) curve analysis of this method shows an area under the curve of 0.937 and diagnostic sensitivity and specificity percentages of 85.65 and 85.92, respectively. This shows that sparse representation of pulse oximetry signals is a very valuable tool for estimating apnea-hypopnea indices. The implementation of the MDCS-OD method could be embedded into the oximeter so as to be used by primary attention clinical physicians in the search and detection of patients suspected of suffering from OSAH.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238780,"idioma_id":4,"titulo":"Empirical Mode Decomposition for adaptive AM-FM analysis of Speech: A Review","resumen":"This work reviews the advancements in the non-conventional analysis of speech signals, particularly from an AM-FM analysis point of view. The benefits of such an analysis, as opposed to the traditional short-time analysis of speech, is illustrated in this work. The inherent non-linearity of the speech production system is discussed. The limitations of Fourier analysis, Linear Prediction (LP) analysis, and the Mel Filterbank Cepstral Coefficients (MFCCs), are presented, thus providing the motivation for the AM-FM representation of speech. The principle and methodology of traditional AM-FM analysis is discussed, as a method of capturing the non-linear dynamics of the speech signal. The technique of Empirical Mode Decomposition (EMD) is then introduced as a means of performing adaptive AM-FM analysis of speech, alleviating the limitations of the fixed analysis provided by the traditional AM-FM methodology. The merits and demerits of EMD with respect to traditional AM-FM analysis is discussed. The developments of EMD to counter its demerits are presented. Selected applications of EMD in speech processing are briefly reviewed. The paper concludes by pointing out some aspects of speech processing where EMD might be explored.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238785,"idioma_id":5,"titulo":"Usos del suelo en el sudeste bonaerense: abundancia y composición de las comunidades microbianas.","resumen":"El cambio en el uso del suelo puede impactar en las condiciones del mismo y por ende, en las comunidades microbianas las cuales son esenciales para el funcionamiento del ecosistema. El objetivo del presente estudio fue evaluar el efecto de usos contrastantes de suelo contrastantes en el tamaño y composición de la comunidad microbiana. Para ello, se seleccionaron lotes con agricultura continua (AC), con un monte de Acacia sp. (MA) y con pradera natural (PN) en un mismo paisaje. Se realizaron muestreos de suelo en la estación cálida y fría, y a 0-5 y 5-20 cm de profundidad, y se determinaron el contenido de humedad y pH. Se cuantificaron y caracterizaron las poblaciones de bacterias aeróbicas mesófilas totales (BAMT), actinomycetes y hongos. El mayor recuento de actinomycetes se registró en MA y PN, y el de hongos en AC, no observándose efecto del uso del suelo en BAMT. La población de los tres grupos microbianos disminuyó con la profundidad como consecuencia de la disminución de la humedad. El recuento de BAMT y actinomycetes fue mayor en la estación cálida asociado a un mayor pH mientras que el de hongos fue superior en la estación fría. Predominaron las bacterias Gram positivas (60%) y con morfología bacilar; sin embargo, su distribución cambió con la profundidad del suelo siendo las bacterias Gram negativas las que prevalecieron en superficie. La población fúngica estuvo representada por especies de los géneros Fusarium, Penicillium, Aspergillus, Eurotium, Trichoderma, Rhizopus, Cladosporium, Acremonium y levaduras, no observándose el predominio de alguna especie asociada con un uso del suelo en particular. Los actinomycetes y hongos presentaron variaciones en sus recuentos en función del uso del suelo por lo que dichos grupos, podrían ser considerados como indicadores biológicos del disturbio en el ecosistema.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238786,"idioma_id":4,"titulo":"Molecular identification and pathogenicity of Rhizoctonia spp. recovered from seed and soil samples of the main bean growing area of Argentina","resumen":"The objective of this study was to perform the molecular and pathogenic characterization of Rhizoctonia solani in bean seed and soil samples from fields with root rot symptoms in northwestern Argentina. Fifty-two Rhizoctonia spp. isolates were collected in ten naturally infested bean fields and characterized by morphological traits, DNA sequencing, and pathogenicity. The mycelium color, the pattern of sclerotia formation, and the number of nuclei per hyphal cell were determined for each isolate. According to the variability in the rDNA-ITS region, isolates were identified as R. solani (85%), Waitea circinata var. zeae (Rhizoctonia zeae) (2%) and Rhizoctonia spp. (13%). Most isolates of R. solani (92%) were found to belong to the anastomosis group (AG) AG 4, including seven AG 4 HG-I and nine AG 4 HG-III isolates. AGs obtained from soil samples were more variable than those obtained from seed samples. Molecular identification of the isolates was in agreement with their morphological characterization. In addition, aggressiveness of the isolates towards bean seedlings was assessed in the greenhouse. Four virulence categories were defined according to the disease reaction on root and foliar tissues, which showed great variability in virulence among the isolates. Our results suggest that both seed and soil-borne inoculum may play a significant role in pathogen dispersal in the region. This is the first study on Rhizoctonia species and AGs in bean seed and soil in this region and it may contribute towards an efficient control strategy for bean diseases caused by Rhizoctonia species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238788,"idioma_id":4,"titulo":"Evaluation of the Health Status of the Silverside (Odontesthes bonariensis) at a RAMSAR Site in South America","resumen":"The objective of this work was to evaluate the health status of an economic and ecologically important fish species from Mar Chiquita Lake, a RAMSAR site located in Cordoba, Argentina, relative to the levels of selected persistent organic pollutants (POPs) in lake water and fish tissues. Odontesthes bonariensis was used as a model species, and its health was estimated by means of histological indices in gills and liver. Sampling was performed according to rainy and dry seasons (i.e. dry, rainy and post-rainy). Gill and liver histopathology were evaluated by semi-quantitative indices and morphometric analysis. Although epithelial lifting in gills and lipid degeneration in liver were frequently registered, they are considered as reversible if environmental conditions improve. During rainy and post-rainy seasons fish presented significantly higher scores of liver and total indices. These higher index scores were correlated with increased levels of POPs in gill and liver tissue. Therefore, preventive measures are needed to mitigate the entry of these compounds into the lake.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238793,"idioma_id":4,"titulo":"Enhancing the potential of methane combined reforming for methanol production via partial CO2 hydrogenation","resumen":"A process for methanol production from high CO2 content natural gas (50 ?60%) is presented and analyzed in technical and economic terms. A conceptual design is proposed on the basis of partial hydrogenation of the feed by the RWGS reaction, prior to a combined reforming operation. Both the RWGS reactor and a Lurgi-type methanol reactor were rigorously simulated via gPROMS by taking into account kinetic expressions of commercial catalysts. The mentioned reactors, the reformer and flash separator were all simulated as separate modules and interconnected as a whole plant. The effect of the CO2 content, the feed fraction to be hydrogenated, the influence of the H2\/CO ratio and the methanol recycle ratio on the total CO2 conversion, the H2 consumption, the methanol reactor size and the CO2 emissions were investigated. It was found that the hydrogenation of 40% of a feed containing 60% CO2 by using a H2\/CO2 ratio of 1.7 followed by a combined reforming furnace leads to a syngas that has an optimum composition for methanol production. An economic analysis demonstrated that the proposed process entails lower investment costs partially due to the smaller reformer size, as compared to a methanol plant of similar production based on CH4 steam reforming. On the other hand, the operating costs are higher mainly due to the cost of H2. Consequently, a negative NPV value is obtained under present market prices. However, for a feed containing 50% CO2 the proposed process would be economically viable for a H2 price of 2.4 U$S\/kg or a methanol price of 500 U$S\/ton. Slightly higher price variations are necessary to obtain a financially feasible project for a feed containing 60% CO2. Nevertheless, the reduced H2 demand has lower economic incidence, as compared to a methanol plant based on CO2 and H2 as raw materials.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238795,"idioma_id":4,"titulo":"The animal model strikes back (one generation)!","resumen":"Genome inheritance is by segments of DNA rather than by independent loci. We introduce the ancestral regression (AR) as a recursive system of simultaneous equations, with grandparental path coefficients as novel parameters. The information given by the pedigree in the AR is complementary with that provided by a dense set of genomic markers, such that the resulting linear function of grandparental BV is uncorrelated to the average of parental BV in the absence of inbreeding. AR is then connected to segmental inheritance by a causal multivariate Gaussian density for BV. The resulting covariance structure (&#931;) is Markovian, meaning that conditional on the BV of parents and grandparents, the BV of the animal is independent of everything else. Thus, an algorithm is presented to invert the resulting covariance structure, with a computing effort that is linear in the number of animals as in the case of the inverse additive relationship matrix.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238796,"idioma_id":4,"titulo":"Evaluating Sequence- Based Genomic Prediction with an Efficient New Simulator","resumen":"ABSTRACT The vast amount of sequence data generated to analyze complex traits is posing new challenges in terms of the analysis and interpretation of the results. Although simulation is a fundamental tool to investigate the reliability of genomic analyses and to optimize experimental design, existing software cannot realistically simulate complete genomes. To remedy this, we have developed a new strategy (Sequence-Based Virtual Breeding, SBVB) that uses real sequence data and simulates new offspring genomes and phenotypes in a very efficient and flexible manner. Using this tool, we studied the efficiency of full sequence in genomic prediction compared to SNP arrays. We used real porcine sequences from three breeds as founder genomes of a 2500-animal pedigree and two genetic architectures: ?neutral? and ?selective.? In the neutral architecture, frequencies and allele effects were sampled independently whereas, in the selective case, SNPs were sites putatively under selection after domestication and a negative correlation between effect and frequency was induced. We compared the effectiveness of different genotyping strategies for genomic selection, including the use of full sequence commercial arrays or randomly chosen SNP sets in both outbred and crossbred experimental designs. We found that accuracy increases using sequence instead of commercial chips but modestly, perhaps by ~4%. This result was robust to extreme genetic architectures. We conclude that full sequence is unlikely to offset commercial arrays for predicting genetic value when the number of loci is relatively large and the prior given to each SNP is uniform. Using sequence to improve selection thus requires optimized prior information and, likely, increased population sizes. The code and manual for SBVB are available at https:\/\/github.com\/mperezenciso\/sbvb0.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238797,"idioma_id":4,"titulo":"Influence of epistasis on response to genomic selection using complete sequence data","resumen":"Background:  The effect of epistasis on response to selection is a highly debated topic. Here, we investigated the impact of epistasis on response to sequence&#8209;based selection via genomic best linear prediction (GBLUP) in a regime of strong non&#8209;symmetrical epistasis under divergent selection, using real Drosophila sequence data. We also explored the possible advantage of including epistasis in the evaluation model and\/or of knowing the causal mutations.Results:  Response to selection was almost exclusively due to changes in allele frequency at a few loci with a large effect. Response was highly asymmetric (about four phenotypic standard deviations higher for upward than downward selection) due to the highly skewed site frequency spectrum. Epistasis accentuated this asymmetry and affected response to selection by modulating the additive genetic variance, which was sustained for longer under upward selection whereas it eroded rapidly under downward selection. Response to selection was quite insensitive to the evaluation model, especially under an additive scenario. Nevertheless, including epistasis in the model when there was none eventually led to lower accuracies as selection proceeded. Accounting for epistasis in the model, if it existed, was beneficial but only in the medium term. There was not much gain in response if causal mutations were known, compared to using sequence data, which is likely due to strong linkage disequilibrium, high heritability and availability of phenotypes on candidates.Conclusions:  Epistatic interactions affect the response to genomic selection by modulating the additive genetic variance used for selection. Epistasis releases additive variance that may increase response to selection compared to a pure additive genetic action. Furthermore, genomic evaluation models and, in particular, GBLUP are robust, i.e. adding complexity to the model did not modify substantially the response (for a given architecture).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238808,"idioma_id":4,"titulo":"The role of hyaluronan as a drug carrier to enhance the bioavailability of extended release ophthalmic formulations. Hyaluronan - timolol ionic complexes as a model case","resumen":"The aim of this work was to obtain information concerning the properties of ophthalmic formulations based on hyaluronic-drug ionic complexes, to identify the factors that determine the onset, intensity and duration of the pharmacotherapeutic effect. Dispersions of a complex of 0.5% w\/v of sodium hyaluronate (HyNa) loaded with 0.5% w\/v of timolol maleate (TM) were obtained and presented a counterionic condensation higher than 75%. For comparison a similar complex obtained with hyaluronic acid (HyH) was also prepared. Although the viscosity of HyNa-TM was significantly higher than that of HyH-TM, in vitro release of TM from both complexes showed a similar extended drug release profile (20?31% over 5 h) controlled by diffusion and ionic exchange. Ocular pharmacokinetic study performed in normotensive rabbits showed that HyNa-TM complex exhibited attractive bioavailability properties in the aqueous humor (AUC and Cmax significantly higher and later Tmax) compared to commercial TM eye-drops. Moreover, a more prolonged period of lowered intra-ocular pressure (10 h) and a more intense hypotensive activity was observed after instillation of a drop of HyNa-TM as compared to the eye-drops. Such behavior was related to the longer pre-corneal residence times (400%) observed with HyNa-TM complex. No significant changes in rabbit transcorneal permeation were detected upon complexation. These results demonstrate that the ability of HyNa to modulate TM release, together with its mucoadhesiveness related to the viscosity, affected both the pharmacokinetic and pharmacodynamic parameters. The HyNa-TM complex is a potentially useful carrier for ocular drug delivery, which could improve the TM efficacy and reduce the frequency of administration to improve patient compliance.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238810,"idioma_id":4,"titulo":"Characterization of a deletion in the Hsp70 cluster in the bovine reference genome","resumen":"The 70 kilodalton heat shock proteins (Hsp70) are highly conserved molecular chaperones which have a crucial role in the stress response of the cell. In mammals, the Hsp70 proteins are encoded by a cluster of three genes: HSPA1A, HSPA1B and HSPA1L. In bovines, this cluster is located on chromosome 23 downstream of the major histocompatibility complex (BoLA). We detected inconsistencies in the location of markers on the Hsp70 genes reported in the literature that pointed to a potential deletion in the bovine reference genome UMD 3.1.1. An in silico analysis of the bovine genomic region of the Hsp70 cluster, using available information from public databases, confirmed the existence of a deletion of 11.1-kb spanning the HSPA1B gene and the intergenic region between HSPA1B and HSPA1A. Although we originally considered this an assembly error, it is most likely a particular condition of L1 Dominette 01449, the cow sequenced in the Bovine Genome Project. Moreover, we suggest a new classification of bovine Hsp70 sequences reported in NCBI and a reassignment of the location of SNPs from dbSNP that map to the deletion on BTA23. We also compared the location of selected transcription factor binding sites on the promoters of HSPA1A and HSPA1B. The results generated in the present work could be helpful to refine the reference genome of an important livestock species and also to understand the role and the regulation of the bovine Hsp70 genes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238811,"idioma_id":4,"titulo":"Generalized sparse discriminant analysis for event-related potential classification","resumen":"A brain?computer interface (BCI) is a system which provides direct communication between the mind of a person and the outside world by using only brain activity (EEG). The event-related potential (ERP)-based BCI problem consists of a binary pattern recognition. Linear discriminant analysis (LDA) is widely used to solve this type of classification problems, but it fails when the number of features is large relative to the number of observations. In this work we propose a penalized version of the sparse discriminant analysis (SDA), called generalized sparse discriminant analysis (GSDA), for binary classification. This method inherits both the discriminative feature selection and classification properties of SDA and it also improves SDA performance through the addition of Kullback?Leibler class discrepancy information. The GSDA method is designed to automatically select the optimal regularization parameters. Numerical experiments with two real ERP-EEG datasets show that, on one hand, GSDA outperforms standard SDA in the sense of classification performance, sparsity and required computing time, and, on the other hand, it also yields better overall performances, compared to well-known ERP classification algorithms, for single-trial ERP classification when insufficient training samples are available. Hence, GSDA constitute a potential useful method for reducing the calibration times in ERP-based BCI systems.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238815,"idioma_id":4,"titulo":"Ant interactions with native and exotic seeds in the Patagonian steppe. Influence of seed traits, disturbance levels and ant assemblage","resumen":"Invasive plants may establish strong interactions with species in their new range which could limit or enhance their establishment and spread. These interactions depend upon traits of the invader and the recipient community, and may alter interactions among native species. In the Patagonian steppe we studied interactions of native ant assemblages with seeds of native and exotic plants, and asked whether ant-seed interactions differ with seed types and disturbance levels and whether the amount and type of ant-seed interactions can be predicted if both ant and seed traits are known. To characterize and quantify ant-seed interactions, we offered baits with large seeds of Pappostipa speciosa (native) and medium-sized elaiosome-bearing seeds of Carduus thoermeri (exotic), near and far from a road (high vs. low disturbed areas), and compared ant abundance and composition between areas. Interaction frequency was the highest for C. thoermeri seeds far from the road. Composition of ants interacting with C. thoermeri in these areas differed from that near the road and from that interacting with native seeds. Ant composition and abundance were similar between areas, but some species interacted more with exotic seeds in low disturbed areas. Ant foraging type predicted ant-seed interactions since the abundance of seed harvesters was positively correlated to interactions with P. speciosa, and that of generalists and predators, with interactions with C. thoermeri. The high interaction of ants with exotic seeds in low invaded areas suggests that ant activity could influence plant invasion, either by predating or dispersing seeds of invasive plants.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238816,"idioma_id":4,"titulo":"Firewood as a pathway for insect introductions. What are the risks of ant invasions in Patagonia?","resumen":"Firewood can act as a long-distance dispersal vector for wood-infesting insects both within and among countries. Recently, we have detected the alien carpenter ant Camponotus mus in firewood transported from central Argentina to Patagonia. This species generates significant economic losses in its native range and has invader potential. Moreover, global warming and the increasing anthropogenic disturbance in Patagonia make this region highly susceptible to insect invasions. This is especially alarming considering the current lack of sanitary controls of incoming goods. To prevent insect introductions via firewood it is crucial to implement a joint effort among the scientific community, control organisms, government, and end user.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238817,"idioma_id":5,"titulo":"Una secuencia didáctica para favorecer la conversión de representaciones semióticas de curvas y regiones del plano complejo","resumen":"En este trabajo se presentan la descripción, y los resultados de la implementación de una secuencia didáctica orientada a favorecer la habilidad de efectuar conversiones de representaciones de curvas y regiones del plano complejo, desde el registro gráfico al registro algebraico. Se detallanlas variables de conversión que regulan los niveles de complejidad en estas actividades cognitivas, que determinaron la estructura de la secuencia didáctica presentada. Esta fue implementada con un grupo de estudiantes de la asignatura Álgebra de primer año de la Facultad de Ingeniería de la Universidad Nacional de Mar del Plata, Argentina. Se evaluó el impacto de la intervención didácticarealizada y se obtuvieron resultados satisfactorios, no solo sobre las conversiones a las que buscó específicamente contribuir, sino también en prácticas matemáticas que requieren otras actividades semióticas vinculadas a representaciones de números complejos en los dos registros considerados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238818,"idioma_id":5,"titulo":"Adaptación y Validación al Español de la Escala de Evaluación de Espiritualidad y Sentimientos Religiosos (ASPIRES): la trascendencia espiritual en el modelo de los cinco factores","resumen":"Uno de los problemas que han presentado las técnicas de evaluación de la religiosidad y la espiritualidad en psicología radica en que la mayoría solamente reflejan las orientaciones cristianas y occidentales. El objetivo de este estudio consiste en adaptar al español la Escala de Evaluación de Espiritualidad y Sentimientos Religiosos (Assessment of Spirituality and Religious Sentiments scale [ASPIRES]), desarrollada por Piedmont (2004) para responder a estos inconvenientes, en una muestra no probabilística incidental compuesta por estudiantes universitarios de la Ciudad Autónoma de Buenos Aires (N=336). En segundo lugar, se pretende explorar si, tal como sugiere la literatura, la espiritualidad puede considerarse un sexto factor dentro del modelo de los cinco factores de la personalidad. El análisis factorial confirmatorio indica un buen ajuste a los datos del modelo propuesto por el autor, por lo que se recomienda su empleo en el contexto local. Se sugiere que futuros estudios exploren las propiedades de ASPIRES en poblaciones diferentes (e.g. religiosas), de modo de contribuir con la generalización y la representatividad de los resultados del presente estudio. A la vez, se observa que la espiritualidad se presenta como un factor independiente dentro del modelo de los cinco factores.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238822,"idioma_id":5,"titulo":"INDICADORES METABÓLICOS SANGUÍNEOS DE GENOTIPOS LECHEROS EN PASTOREO DE LA PROVINCIA DE NAPO-ECUADOR","resumen":"El objetivo de este trabajo fue evaluar el metabolismo energético\/proteico en sangre de vacas lecheras de cuatrogenotipos de primera lactancia en condiciones de pastoreo en el cantón Arosemena Tola, Napo, Ecuador. Se evaluaron36 vacas lecheras de primer parto cruzas de los genotipos: Bos Indicus x Gir (GIR), Bos Indicus x Brown Swiss (BS),Bos Indicus x Jersey (J) y Bos Indicus x Sahiwal (S). Se tomaron muestras de sangre de la vena coccígea los días 60 y21 antes del parto, al momento del parto y a los 30, 60 y 90 días después del parto. Se determinaron los valores enplasma de, glucosa, urea, creatinina y proteínas totales. Ninguna de las variables presentó diferencias significativas(p&#8805;0,05) entre razas y los valores obtenidos para todos se encontraron por debajo de los valores normales para lasvacas lecheras. La glucosa no mostró diferencias significativas (p&#8805;0,05) en el tiempo. En cambio, para Urea, Creatininay Proteínas Totales existieron diferencias significativas (p&#8805;0,001) a través del tiempo. Utilizando una regresión localcon parámetro de suavizado igual a 0,8 para estudiar cómo era la trayectoria de la variable en el tiempo. Luego, seajustó un modelo lineal mixto para cada variable, considerando un nodo en los casos para los cuales se observaba uncambio en la trayectoria en algún tiempo en particular (según lo observado en el gráfico 1, 2 y 3 de la regresión local).Se concluye que para los cuatro genotipos lecheros estudiados no se encontró diferencias en la concentración de losindicadores metabólicos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238836,"idioma_id":4,"titulo":"Towards a new paradigm for rural extensionists&rsquo; in-service training","resumen":"Changes in the conceptions of extension and rural innovation, as well as the persistence of diffusionist extension approaches, require rethinking training strategies for rural extensionists. Drawing upon conceptual insights pertaining to the theory of action, the social learning theory, and the communities of practice framework, in this paper, current training and educational strategies for extensionists will be critically reflected upon, lessons learnt will be extracted, and proposals will be generated. Amongst them, the need for expanding and reframing what we understand ?training extensionists? to be, overcoming the traditional transfer-of-knowledge approach, focusing on the reflection on practice process, supporting the horizontal exchange of knowledge and experiences, and facilitating the development of extensionist communities of practice, are highlighted. Finally, it is argued that there is a need for advancing the conceptual discussion, systematizing innovative training practices, and researching trainings for extensionists and their impact.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238839,"idioma_id":5,"titulo":"Rol de los psicólogos en la extensión rural desde el punto de vista de los extensionistas del noreste argentino","resumen":"La extensión rural es una práctica compleja que involucra asistencia técnica y asesoría a productores y a otros actores rurales con el fin de que éstos puedan fortalecer su producción y sus dinámicas organizativas y comerciales. Vista así, resulta claro que la extensión rural es una práctica interdisciplinaria que requiere contribuciones de las diferentes ciencias sociales. En consecuencia, puede afirmarse que la psicología posee una importante potencialidad para contribuir a la extensión rural. No obstante, se observa que sus contribuciones al área han sido escasas. Así, buscando comprender el rol potencial de los psicólogos en la extensión rural se realizó una investigación cualitativa, de carácter exploratorio-descriptivo centrada en la realización de 40 entrevistas a extensionistas del noreste argentino. Las entrevistas fueron grabadas y luego analizadas siguiendo los principios de la teoría fundamentada, utilizando el software Atlas Ti. Se concluye que la mayor parte de los extensionistas consideran que la psicología podría contribuir a su labor, aún sin poder clarificar sus especificidades. Se destaca la posibilidad de contribuir al manejo de grupos, a la gestión de conflictos y a la comprensión de los productores.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238841,"idioma_id":4,"titulo":"Morphometric correlation between Apis mellifera morphotypes (Hymenoptera) and Varroa destructor (Acari) from Uruguay","resumen":"Uruguay se caracteriza por tener un gradiente de africanización en sus poblaciones de abeja de la miel (Apis mellifera), desde las áreas que bordean Brasil hasta las regiones más remotas.Estas diferencias morfológicas también han sido encontradas en las poblaciones de Varroa destructor en diferentes regiones. Una explicación posible para estos cambios morfológicos en los ácaros podría ser explicada por la correlación morfológica entre hospedador y parásito, A. mellifera y V. destructor. El objetivo del presente estudio es identificar los ecotipos de A. mellifera en Uruguay y su correlación con las poblaciones de V. destructor usando análisis de morfometría geométrica. Nuestra hipótesis de partida es que hay un gradiente de africanización en A. mellifera en dirección norte-sureste en Uruguay y que se correlaciona con variaciones morfológicas en las poblaciones de V. destructor. Un análisis morfométrico de seis poblaciones de abeja de la miel y sus respectivos ácaros fóreticos fue llevado a cabo muestreando en zonas de la región uruguaya en las que se apreciaba el gradiente. Como resultado principal se obtuvo una correlación morfométrica entre abejas y ácaros. El uso de landmarks puede ser ajustado para la diferenciación intraespecífica de las poblaciones de V. destructor, lo que no había sido considerado previamente. Estos estudios son de gran importancia para entender el parasitismo causado por V. destructor en las abejas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238842,"idioma_id":4,"titulo":"Nosema ceranae in South American Native Stingless Bees and Social Wasp","resumen":"Besides the incipient research effort, the role of parasites as drivers of the reduction affecting pollinator populations is mostly unknown. Given the worldwide extension of the beekeeping practice and the diversity of pathogens affecting Apis mellifera populations, honey bee colonies are a certain source of parasite dispersion &#65279;to other species. Here, we communicate the detection of the microsporidium Nosema ceranae, a relatively new parasite of honey bees, in stingless bees (Meliponini) and the social wasp Polybia scutellaris (Vespidae) samples from Argentina and Brazil by means of duplex PCR. Beyond the geographic location of the nests, N. ceranae was detected in seven from the eight Meliponini species analyzed, while Nosema apis, another common parasite of A. mellifera, was absent in all samples tested. Further research is necessary to determine if the presence of the parasite is also associated with established infection in host tissues. The obtained information enriches the current knowledge about pathologies that can infect or, at least, be vectored by native wild pollinators from South America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238843,"idioma_id":5,"titulo":"reseña del libro de Patricia Aguirre 'Una historia social de la comida'","resumen":"Una reseña del libro de Patricia Aguirre 'Una historia social de la comida'","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238844,"idioma_id":4,"titulo":"Doctor-patient relationships amid changes in contemporary society: a view from the health communication field","resumen":"Este trabajo propone describir y comprender la relación médico-paciente (RMP) a través de una revisión de la bibliografía entre 1980-2015. El enfoque teórico reúne los procesos modernizadores de la sociedad contemporánea y la perspectiva de Comunicación y Salud. Fueron seleccionados ochenta y cuatro artículos delimitando un corpus por criterios teóricos y se analizó por contenidos temáticos. De los resultados surge que la literatura se divide en reflexiones teórico-conceptuales e investigaciones empíricas. Se evidencia una trasformación sociocomunicacional, donde la concepción del paciente, si bien con matices, esla de una persona activa y con derechos. Respecto de la satisfacción del paciente y los modelos de relación, la eHealth se ha convertido en el eje principal de transformación, reflexión e investigación sobre la RMP.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238846,"idioma_id":4,"titulo":"First identification of Nosema ceranae (Microsporidia) infecting Africanized Honeybees in Venezuela","resumen":"Nosema ceranae is a pathogen of Apis mellifera, which seems to have jumped from its original host Asiatic honey bee Apis ceranae. Nosemosis which affects the honey bee Apis mellifera is caused by two parasitic fungi described as etiologic agents of the disease. Nosema apis was the only microsporidian infection identified in A. mellifera until N. ceranae in Taiwan and Europe. Nosema spp. positive samples of adult worker bees from the Venezuelean state of Lara were determined through light microscopy of spores. Samples were then tested to determine Nosema species (N.apis\/N.ceranae) using previously reported PCR primers for the 16S rRNA gene. A multiplex PCR assay was used to differentiate both N. apis and N. ceranae species. Only N. ceranae was found in the analyzed samples and the percentage of infected foragers fluctuated between 18% and 60%.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238847,"idioma_id":4,"titulo":"Current knowledge on commercially important fish stocks of Buenos Aires Coastal Ecosystem","resumen":"This paper provides a literature review of studies dealing with the stock assessment of eight bony demersal fish exploited on the Buenos Aires coast (35°S - 41°S). The objective was to determine the existence of population differences between fish sampled in the Río de la Plata estuary and El Rincón areas using biological data. The results obtained from the analysis of most phenotypic and environmental characteristics, indicated, to a large extent, the presence of two stocks. By contrast, all genetic studies identified a single genetic unit in the study area. In this sense, the phenotypic variation owing to environmental influence was larger than the neutral genetic variation detected. Indeed further studies on the genetic basis of differentiation using more neutral or adaptive markers are required to distinguish local populations. In addition, genetic monitoring on marine fishes plays a key part on the conservation of biodiversity, allowing managers to estimate effective population numbers, and assess the changes in variability that could be affecting long term sustainability.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238848,"idioma_id":4,"titulo":"Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis","resumen":"Molecular mechanisms on sepsis progression are linked to the imbalance between reactive oxygen species (ROS) production and cellular antioxidant capacity. Previous studies demonstrated that benznidazole (BZL), known for its antiparasitic action on Trypanosoma cruzi, has immunomodulatory effects, increasing survival in C57BL\/6 mice in a model of polymicrobial sepsis induced by cecal ligation and puncture (CLP). The mechanism by which BZL inhibits inflammatory response in sepsis is poorly understood. Also, our group recently reported that BZL is able to activate the nuclear factor erytroide-derived 2-Like 2 (NRF2) in vitro. The aim of the present work was to delineate the beneficial role of BZL during sepsis, analyzing its effects on the cellular redox status and the possible link to the innate immunity receptor TLR4. Specifically, we analyzed the effect of BZL on Nrf2 regulation and TLR4 expression in liver of mice 24hours post-CLP. BZL was able to induce NRF2 nuclear protein localization in CLP mice. Also, we found that protein kinase C (PKC) is involved in the NRF2 nuclear accumulation and induction of its target genes. In addition, BZL prompted a reduction in hepatic CLP-induced TLR4 protein membrane localization, evidencing its immunomodulatory effects. Together, our results demonstrate that BZL induces hepatic NRF2 activation with the concomitant increase in the antioxidant defenses, and the attenuation of inflammatory response, in part, by inhibiting TLR4 expression in a murine model of sepsis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238849,"idioma_id":4,"titulo":"Death of adrenocortical cells during murine acute T. cruzi infection is not associated with TNF-R1 signaling but mostly with the type II pathway of Fas-mediated apoptosis","resumen":"Earlier studies from our laboratory demonstrated that acute experimental Trypanosoma cruzi infection promotes an intense inflammation along with a sepsis-like dysregulated adrenal response characterized by normal levels of ACTH with raised glucocorticoid secretion. Inflammation was also known to result in adrenal cell apoptosis, which in turn may influence HPA axis uncoupling. To explore factors and pathways which may be involved in the apoptosis of adrenal cells, together with its impact on the functionality of the gland, we carried out a series of studies in mice lacking death receptors, such as TNF-R1 (C57BL\/6-Tnfrsf1a tm1Imx or TNF-R1&#8722;\/&#8722;) or Fas ligand (C57BL\/6 Fas-deficient lpr mice), undergoing acute T. cruzi infection. Here we demonstrate that the late hypercorticosterolism seen in C57BL\/6 mice during acute T. cruzi infection coexists with and hyperplasia and hypertrophy of zona fasciculata, paralleled by increased number of apoptotic cells. Apoptosis seems to be mediated mainly by the type II pathway of Fas-mediated apoptosis, which engages the mitochondrial pathway of apoptosis triggering the cytochrome c release to increase caspase-3 activation. Fas-induced apoptosis of adrenocortical cells is also related with an exacerbated production of intra-adrenal cytokines that probably maintain the late supply of adrenal hormones during host response. Present results shed light on the molecular mechanisms dealing with these phenomena which are crucial not only for the development of interventions attempting to avoid adrenal dysfunction, but also for its wide occurrence in other infectious-based critical illnesses.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238850,"idioma_id":4,"titulo":"Alpha hemoglobinophaties in Rosario, Argentina","resumen":"Hemoglobinopathies are the most common recessive diseases worldwide. Whilethe molecular basis of b-thalassemia in Rosario has been addressed, that of &#945;-thalassemia and &#945; structural alterations, has not. In this study 105 individuals from different families referred to our center were investigated for alpha hemoglobinopathies because of low MCV (15%. Six of them with a clinical phenotype of thalassemia intermedia were diagnosed as Hb H disease (fivecases) and Hb H like (one case). It also included one patient with sickle cell trait, confirmed by hematological and molecular studies. We were able to identify alpha globin genes mutations in 92 individuals (87.6%): 88 patients with alpha thalassemia, 3 patients with structural alterations and one with both. In total, 13 individuals (12.4%) had no identified &#945;-globin mutation. This study is the first to deal with the molecular basis of &#945;-hemoglobinophatiesin Rosario.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238851,"idioma_id":5,"titulo":"Diagnóstico molecular de hemocromatosis hereditaria","resumen":"La HH es un desorden autosómico recesivo del metabolismo del hierro con aumento de su absorción y reserva. Es una de las enfermedades más comunes en la población caucásica y presenta una prevalencia variable entre diferentes grupos étnicos. Puede ser el resultado de defectos en el gen HFE (tipo 1) o de defectos no asociados con éste. El gen HFE fue clonado, identificándose una mutación puntual G&#8594;A resultando en una sustitución de cisteína por tirosina (C282Y), reportada en alrededor del 80% de los pacientes estudiados con HH tipo 1 en ciertas regiones de Europa. Otras dos mutaciones en HFE fueron descriptas; un cambio de histidina por ácido aspártico en el aminoácido 63 (H63D) hallada en un 15-20% y un cambio de serina por cisteína en la posición 65 (S65C) hallada con muy baja frecuencia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238852,"idioma_id":5,"titulo":"Necesidad del uso de inhibidor de ribonucleasas para el diagnóstico molecular de muestras con eosinofilia","resumen":"Los eosinófilos son granulocitos polimorfonucleares que se diferencian a partir de una célula madre hematopoyética en la médula ósea. Dentro de sus funciones protectoras se encuentra la producción de radicales libres y liberación del contenido de sus gránulos citoplasmáticos. Las proteínas que éstos contienen son responsables de muchas funciones proinflamatorias y citotóxicas. Dentro de los gránulos específicos se encuentran la Proteína básica principal, Proteína catiónica eosinofílica (ECP), Neurotoxina derivada de eosinófilos (EDN), Peroxidasa de eosinófilo, hidrolasas lisosomales e histaminasa. La  ECP (RNAsa 3) y EDN (RNAsa2) pertenecen a la superfamilia RNasa A y la función de estas enzimas es hidrolizar y degradar el RNA.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238853,"idioma_id":5,"titulo":"Perfil de mutaciones causantes de trombocitemia esencial (TE) y mielofibrosis primaria (MFP)","resumen":"Policitemia Vera (PV), Trombocitemia Esencial (TE) y Mielofibrosis Primaria (MFP), constituyen un grupo de enfermedades hematológicas malignas que se caracterizan por una producción aumentada de uno o más tipos celulares sanguíneos. La etiología molecular está relacionada con mutaciones que producen activación de la vía de señalización intracelular JAK\/STAT. El descubrimiento de la mutación JAK2V617F ha representado un gran avance en el conocimiento de la patogénesis y el diagnóstico de estas patologías. Posteriormente, fueron identificadas mutaciones en el exón 10 del receptor de trombopoyetina (MPL) y más recientemente  inserciones o deleciones en el exón 9 del gen de Calreticulina (CALR).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238854,"idioma_id":5,"titulo":"Mutaciones en el domino quinasa de BCR\/ABL en pacientes con Leucemia Mieloide Crónica (LMC) resistentes al tratamiento","resumen":"La LMC es una enfermedad clonal de la stem cell hematopoyética. Es causada por la translocación t(9;22), que da origen al gen de fusión bcr\/abl que codifica una tirosinquinasa (TK) constitutivamente activa. Imatinib fue el primer inhibidor de TK (ITK) aprobado para el tratamiento de la LMC en 2001. Posteriormente fueron aprobados otros ITK como Dasatinib y Nilotinib y más tarde fueron desarrollados Bosutinib y Ponatinib. Si bien el tratamiento con ITK es altamente efectivo, un tercio de pacientes que inician terapia con Imatinib experimentan resistencia al tratamiento manifestándose como falta o pérdida de respuesta o como progresión de la enfermedad. Aproximadamente la mitad de los pacientes con resistencia a los ITK tienen mutaciones en el dominio kinasa de BCR\/ABL.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238855,"idioma_id":4,"titulo":"Selective Hydrogenation of Citral with Carbon Nanotubes Supported Bimetallic Catalysts Prepared by Deposition&ndash;Reduction in Liquid Phase and Conventional Impregnation Methods","resumen":"This paper studies the preparation of Pt-based bimetallic (PtFe, PtSn, PtIn and PtGa) catalysts supported on carbon nanotubes for the citral hydrogenation by deposition?reduction in liquid phase and their comparison with the conventional impregnation method (CI). When conventionally impregnated, the selectivity to unsaturated alcohols (UA) highly increased from the monometallic to the bimetallic samples, whereas for liquid phase reduced ones, the selectivity to UA was rather similar for both Pt and bimetallic samples except for PtFe ones and for the PtSn catalyst treated treated with N2. The results were explained taken into account the intimate interaction achieved between the metals according to the preparation method and the formation of Pt?promotor complexes in the impregnating solution. Graphical Abstract: [Figure not available: see fulltext.].","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238856,"idioma_id":4,"titulo":"Synthesis of spherical structured catalysts by dip-coating. Application to n-butane dehydrogenation","resumen":"This work analyzes the deposition conditions of thin layers of gamma-Al2O3 by dip-coating on a spherical substrate of alfa-Al2O3 spheres. Results showed that under controlled deposition conditions, a structured support of alfa-Al2O3 spheres coated by a uniform gamma-Al2O3 layer (thickness 15 &#956;m) of good adherence, can be attained. Optimal preparation conditions for the coating, that involved pretreatment of the substrate, gel formation, deposition conditions and thermal treatments, were obtained.Pt catalysts supported on this structured material can be used as promising dehydrogenation systems. In this sense, a monometallic structured catalyst showed both good metallic dispersion and catalytic performance in n-butane dehydrogenation reaction compared to another conventional catalytic system.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238857,"idioma_id":4,"titulo":"Unilateral Head Impulses Training in Uncompensated Vestibular Hypofunction","resumen":"The aim of this paper is to report a case of a young woman with unilateral vestibular chronic failure with a poorly compensated vestibuloocular reflex during rapid head rotation. Additionally, she developed migraine symptoms during the treatment with associated chronic dizzy sensations and blurred vision. Her report of blurred vision only improved after she completed a rehabilitation program using fast head impulse rotations towards the affected side for 5 consecutive days. We discuss why we elected this form of treatment and how this method may be useful for different patients.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238859,"idioma_id":4,"titulo":"Evidence of positive selection towards Zebuine haplotypes in the BoLA region of Brangus cattle","resumen":"The Brangus breed was developed to combine the superior characteristics of both of its founder breeds, Angus and Brahman. It combines the high adaptability to tropical and subtropical environments, disease resistance, and overall hardiness of Zebu cattle with the reproductive potential and carcass quality of Angus. It is known that the major histocompatibility complex (MHC, also known as bovine leucocyte antigen: BoLA), located on chromosome 23, encodes several genes involved in the adaptive immune response and may be responsible for adaptation to harsh environments. The objective of this work was to evaluate whether the local breed ancestry percentages in the BoLA locus of a Brangus population diverged from the estimated genome-wide proportions and to identify signatures of positive selection in this genomic region. For this, 167 animals (100 Brangus, 45 Angus and 22 Brahman) were genotyped using a high-density single nucleotide polymorphism array. The local ancestry analysis showed that more than half of the haplotypes (55.0%) shared a Brahman origin. This value was significantly different from the global genome-wide proportion estimated by cluster analysis (34.7% Brahman), and the proportion expected by pedigree (37.5% Brahman). The analysis of selection signatures by genetic differentiation (F st) and extended haplotype homozygosity-based methods (iHS and Rsb) revealed 10 and seven candidate regions, respectively. The analysis of the genes located within these candidate regions showed mainly genes involved in immune response-related pathway, while other genes and pathways were also observed (cell surface signalling pathways, membrane proteins and ion-binding proteins). Our results suggest that the BoLA region of Brangus cattle may have been enriched with Brahman haplotypes as a consequence of selection processes to promote adaptation to subtropical environments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238860,"idioma_id":4,"titulo":"Genomic differentiation between Asturiana de los Valles, Avile&ntilde;a-Negra Ib&eacute;rica, Bruna dels Pirineus, Morucha, Pirenaica, Retinta and Rubia Gallega cattle breeds","resumen":"The Spanish local beef cattle breeds have most likely common origin followed by a process of differentiation. This particular historical evolution has most probably left detectable signatures in the genome. The objective of this study was to identify genomic regions associated with differentiation processes in seven Spanish autochthonous populations (Asturiana de los Valles (AV), Avileña-Negra Ibérica (ANI), Bruna dels Pirineus (BP), Morucha (Mo), Pirenaica (Pi), Retinta (Re) and Rubia Gallega (RG)). The BovineHD 777K BeadChip was used on 342 individuals (AV, n=50; ANI, n=48; BP, n=50; Mo, n=50; Pi, n=48; Re, n=48; RG, n=48) chosen to be as unrelated as possible. We calculated the fixation index (F ST) and performed a Bayesian analysis named SelEstim. The output of both procedures was very similar, although the Bayesian analysis provided a richer inference and allowed us to calculate significance thresholds by generating a pseudo-observed data set from the estimated posterior distributions. We identified a very large number of genomic regions, but when a very restrictive significance threshold was applied these regions were reduced to only 10. Among them, four regions can be highlighted because they comprised a large number of single nucleotide polymorphisms and showed extremely high signals (Kullback?Leiber divergence (KLD)>6). They are located in BTA 2 (5 575 950 to 10 152 228 base pairs (bp)), BTA 5 (17 596 734 to 18 850 702 bp), BTA 6 (37 853 912 to 39 441 548 bp) and BTA 18 (13 345 515 to 15 243 838 bp) and harbor, among others, the MSTN (Myostatin), KIT-LG (KIT Ligand), LAP3 (leucine aminopeptidase 3), NAPCG (non-SMC condensing I complex, subunit G), LCORL (ligand dependent nuclear receptor corepressor-like) and MC1R (Melanocortin 1 receptor) genes. Knowledge on these genomic regions allows to identify potential targets of recent selection and helps to define potential candidate genes associated with traits of interest, such as coat color, muscle development, fertility, growth, carcass and immunological response.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238861,"idioma_id":4,"titulo":"Performance of genomic selection under a single-step approach in autochthonous Spanish beef cattle populations","resumen":"This study evaluated different strategies for implementing a single-step genomic selection programme in two autochthonous Spanish beef cattle populations (Pirenaica?Pi and Rubia Gallega?RG). The strategies were compared in terms of accuracy attained under different scenarios by simulating genomic data over the known genealogy. Several genotyping approaches were tested, as well as, other factors like marker density, effective population size, mutation rate and heritability of the trait. The results obtained showed gains in accuracy with respect to pedigree BLUP evaluation in all cases. The greatest benefit was obtained when the candidates to selection had their genotypes included in the evaluation. Moreover, genotyping the individuals with the most accurate predictions maximized the gains but other suboptimal strategies also yielded satisfactory results. Furthermore, the gains in accuracy increased with the marker density reaching a plateau at around 50,000 markers. Likewise, the effective population size and the mutation rate have also shown an effect, both increasing the accuracy with decreasing values of these population parameters. Finally, the results obtained for the RG population showed greater gains compared to the Pi population, probably attributed to the wider implantation of artificial insemination.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238862,"idioma_id":4,"titulo":"Beyond genomic selection: The animal model strikes back (one generation)!","resumen":"Genome inheritance is by segments of DNA rather than by independent loci. Weintroduce the ancestral regression (AR) as a recursive system of simultaneousequations, with grandparental path coefficients as novel parameters. The information given by the pedigree in the AR is complementary with that provided by a dense set of genomic markers, such that the resulting linear function of grandparental BV is uncorrelated to the average of parental BV in the absence ofinbreeding. AR is then connected to segmental inheritance by a causal multivariate Gaussian density for BV. The resulting covariance structure (&#931;) is Markovian, meaning that conditional on the BV of parents and grandparents, the BV of the animal is independent of everything else. Thus, an algorithm is presented to invert the resulting covariance structure, with a computing effort that is linear in the number of animals as in the case of the inverse additive relationship matrix.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238863,"idioma_id":5,"titulo":"Hipertiroidismo en un paciente canino con carcinoma folicular tiroideo","resumen":"En condiciones normales, la glándula tiroides no es palpable en perros, pero ante la presencia de tumores, generalmentemalignos, es fácil de identificar. Los tumores tiroideos representan el 1-4 % de todas las neoplasias caninas,manifestándose como eutiroideos o hipotiroideos. Cerca del 10 % de los casos exhiben signos de hipertiroidismo,que casi siempre se asocia con cáncer tiroideo. El objetivo de este trabajo es describir un caso de neoplasiade tiroides en un canino macho de 10 años, que llegó a la consulta por presentar una deformación en la regiónventrocervical y manifestar signos de hipertiroidismo tales como: poliuria, polidipsia, polifagia, pérdida de peso ydisfagia, entre otros. Se realizó la palpación de la región cervical hallándose una masa móvil, no adherida a tejidosadyacentes. Se obtuvo una muestra de la misma por punción-aspiración con aguja fina (PAAF) para citología queevidenció la presencia de células carcinomatosas. Se extrajo una muestra de sangre para hemograma, bioquímicasérica y medición de hormona T4 libre, que estaba aumentada. La ecografía de la región del cuello reveló una imagencompatible con neoplasia tiroidea en el lóbulo izquierdo. El estudio histopatológico estableció que el carcinoma erade tipo folicular. Los incrementos anormales de la tiroxinemia confirmaron el diagnóstico de hipertiroidismo y, anteesta situación, debería sospecharse de un carcinoma funcional como causa.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238873,"idioma_id":4,"titulo":"Brief history of agroecology in Argentina: origins, evolution, and future prospects","resumen":"Agroecology emerged as a new approach and paradigm of agricultural science to provide strategies for the design, evaluation, and management of sustainable agroecosystems. It arose as a reaction to the consequences of an environmentally unsustainable and socially exclusive production model. Due to its multidisciplinary and pluri-epistemological character, its scientific approach as a movement, and a series of strategies and techniques, the incorporation and consolidation of agroecology in Argentina recognizes different goals, actors, and stages. The role of nongovernmental organizations, governmental institutions, universities, other educational institutions, and farmers&rsquo; organizations is analyzed, and the potential and limitations for future expansion are discussed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238874,"idioma_id":5,"titulo":"Mezcla de cultivares de colza canola como una alternativa ecológica para mejorar el uso de los recursos en un sistema de producción extensivo de clima templado","resumen":"Se evaluaron mezclas de variedades de colza canola como una alternativa para aumentar labiodiversidad cultivada y mejorar el uso de los recursos en sistemas extensivos de clima templado. Se condujerondos ensayos a campo. En el ensayo 1 , se mezclaron dos cultivares, en diferentes proporciones, bajo dos niveles dedisponibilidad de nitrógeno. En el ensayo 2, se evaluaron cinco cultivares en diferentes combinaciones. Elrendimiento fue mayor en las mezclas que en los monocultivos, indicando un efecto complementario en el uso derecursos, especialmente en condiciones limitantes de nitrógeno, sin fertilizante. El mejor resultado se observócuando se mezclaron los cultivares Impulse y Nolza 531 . Los resultados sugieren que el uso de mezclas devariedades de colza canola, apropiadamente seleccionadas, puede ser una alternativa ecológica para aumentar ladiversidad cultivada en sistemas extensivos de clima templado y traducirse en un mejor aprovechamiento de losrecursos, lo que resulta importante para sistemas en transición agroecológica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238875,"idioma_id":5,"titulo":"Análisis del impacto ambiental del cambio de secuencias de cultivo en el partido de Tres Arroyos (Buenos Aires, Argentina)","resumen":"El uso de plaguicidas es cuestionado por su peligrosidad para el ser humano, sus efectos sobre organismos noblanco y contaminación de distintos compartimentos ambientales. Los diferentes usos del territorio, sea pordiferentes cultivos o modelos de producción, determinan diferentes usos (tipo y dosis) de plaguicidas, condiferentes impactos ambientales. Los cambios que se están registrando en los sistemas productivos del Partidode Tres Arroyos justifican analizar estos aspectos en diferentes alternativas productivas. El objetivo de estetrabajo es evaluar el impacto del uso de plaguicidas de las secuencias trigo\/soja, colza\/soja y cebada\/sojacultivadas bajo dos modelos de producción (nivel tecnológico medio y alto) en dos áreas ambientalmentediferentes (zona de suelos someros y profundos) del Partido de Tres Arroyos. Para evaluar el impacto asociadoal uso de plaguicidas se utilizó el ?coeficiente de impacto ambiental de plaguicidas? y su ?valoración de uso acampo?. La secuencia colza\/soja mostró el mayor impacto, posiblemente por una menor adaptación ecológica delos cultivos que la componen. En el nivel tecnológico medio, los sistemas cebada\/soja y trigo\/soja tuvieron muybajos impactos comparativos respecto de colza\/soja, pero, con la tecnología alta, las tres secuencias aumentaronsu impacto a niveles similares, mostrando la importancia del modelo de producción en el efecto que las prácticasagrícolas para el control de plagas tienen sobre el ambiente. El principal responsable del impacto ambiental fueel glifosato. Se plantea la necesidad de un cambio de ética y valores en la sociedad para transitar hacia unacultura de la sostenibilidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238876,"idioma_id":5,"titulo":"Las relaciones ecológicas: un aspecto central en el rediseño de agroecosistemas sustentables, a partir de la Agroecología.","resumen":"La Agroecología surge como un nuevo paradigma de las ciencias agrarias para generarconocimientos para la evaluación, diseño y manejo de agroecosistemas sustentables. Uno delos mayores desafíos en la actualidad, es lograr disminuir o eliminar el uso de insumos (caros ypeligrosos). Ello requiere cambios en el diseño y manejo de los agroecosistemas, de manera defortalecer los procesos ecológicos que brinda la biodiversidad. Estos servicios ecológicos son elproducto de muchas interacciones entre los diferentes componentes de la biodiversidadcultivada y espontánea en los agroecosistemas. Manipular esta biodiversidad de maneraexitosa a fin de optimizar las interacciones positivas y disminuir las negativas requiereconocimientos de la ecología para entender el funcionamiento de los agroecosistemas comosistemas complejos. En este capítulo se abordan los principales conocimientos a tener encuenta y se analiza su utilidad con un ejemplo en sistemas pampeanos argentinos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238878,"idioma_id":4,"titulo":"Hypothyroidism reduces mammary tumor progression via &Beta;-catenin-activated intrinsic apoptotic pathway in rats","resumen":"Experimental hypothyroidism retards mammary carcinogenesis promoting apoptosis of tumor cells. &#946;-catenin plays a critical role in cell adhesion and intracellular signaling pathways conditioning the prognosis of breast cancer. However, the mechanistic connections associated with the expression of &#946;-catenin in thyroid status and breast cancer are not known. Therefore, we studied the relationship between the expression and localization of &#946;-catenin and apoptosis in mammary tumors induced by 7,12-dimethylbenz(a)anthracene (DMBA) in hypothyroid (Hypot) and euthyroid (EUT) rats. Female Sprague Dawley rats were treated with a dose of DMBA (15 mg\/rat) at 55 days of age and were then divided into two groups: HypoT (0.01% 6-N-propyl-2-thiouracil in drinking water, n&#8201;=&#8201;54) and EUT (untreated control, n&#8201;=&#8201;43). Latency, incidence and progression of tumors were determined. At sacrifice, tumors were obtained for immunohistological studies and Western Blot. The latency was longer (p&#8201;<&#8201;0.05), the incidence was lower (p&#8201;<&#8201;0.0001) and tumor growth was slower (p&#8201;<&#8201;0.01) in HypoT rats compared to EUT. The expression of Bax, cleaved caspase-9 and caspase-3 was significantly higher in tumors of HypoT than in EUT (p&#8201;<&#8201;0.05) indicating the activation of the intrinsic pathway. In this group, &#946;-catenin was expressed in the plasma membrane and with less intensity, while its expression was nuclear and with greater intensity in the EUT (p&#8201;<&#8201;0.05). Moreover, the expression of survivin was reduced in tumors of HypoT rats (p&#8201;<&#8201;0.05). In conclusion, decreased expression of &#946;-catenin and its normal location in membrane of mammary tumors are associated with augmented apoptosis via activation of the intrinsic pathway in HypoT rats.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238880,"idioma_id":4,"titulo":"Performance of níquel\/alumina catalysts obtained by aluminum recycling in biogas dry reforming","resumen":"In this paper was proposed a new preparation route of Ni\/Al2O3, using alumina synthesized fromaluminum cans powders. Obtained catalysts were tested in methane dry reforming and showed a goodperformance: high methane conversion (68-78%), high carbon-dioxide conversion (76-91%), highselectivity to hydrogen (84%) and H2\/CO molar ratio close to 1, being the idea promising for futureindustrial applications","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238881,"idioma_id":5,"titulo":"Comportamiento del eje tiroideo en pacientes con diagnóstico positivo a leishmaniosis visceral canina","resumen":"A nivel hipotalámico- hipofisiario, laconcentración sérica de hormona tiroidea puedeverse afectada en respuesta a enfermedadesconcurrentes. La leishmaniosis visceral canina esuna enfermedad sistémica de gravedad variableque podría alterar dichas hormonas. Con el finde observar y comparar el comportamientodel eje hipotalámico hipofisiario tiroideo, seanalizaron siete pacientes caninos, cuatrohembras y tres machos, entre tres y cincoaños de edad, con diagnóstico clínico y delaboratorio positivo a leishmaniosis canina.Las determinaciones plasmáticas de tiroxina(T4 libre) se mantuvieron dentro de los límitesnormales para la especie (0,6-1,50 ng\/dl),excepto en dos de los ellos: una hembra (1,80ng\/dl) y un macho (2,60 ng\/dl). Con respecto alos niveles de la hormona tiroestimulante (TSH),también se hallaron entre los parámetrosnormales, con la excepción de un macho, en elque se encontró un nivel elevado (0.73 ng\/dl). Sibien la medición de TSH y T4 libre se consideramás representativa del estado tiroideo enperros con enfermedades concurrentes, no seevidenció disfunción alguna del eje hipotálamohipofisario tiroideo en la mayoría de los casosanalizados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238888,"idioma_id":4,"titulo":"A cooperative conjugate gradient method for linear systems permitting efficient multi-thread implementation","resumen":"This paper revisits, in a multi-thread context, the so-called multi-parameter or block conjugate gradient (B-CG) methods, first proposed as sequential algorithms by O?Learyand Brezinski, for the solution of the linear system Ax = b, for an n-dimensional symmetric positive definite matrix A. Instead of the scalar parameters of the classical CG algorithm,which minimizes a scalar functional at each iteration, multiple descent and conjugate directions are updated simultaneously. Implementation involves the use of multiple threads and the algorithm is referred to as cooperative CG (CCG) to emphasize that each thread now uses information that comes from the other threads. It is shown that for a sufficiently large matrix dimension n, the use of an optimal number of threads results in a worst case flop count O^(n7\/3) in exact arithmetic. Numerical experiments on a multi-core, multi-thread computer, for synthetic and real matrices, illustrate the theoretical results.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238889,"idioma_id":4,"titulo":"Catalytic paper made from ceramic fibres and natural ulexite. Application to diesel particulate removal","resumen":"Ceramic paper discs were made by employing a dual papermaking technique and by partially substituting cellulosic fibres by SiO2-Al2O3ceramic ones. Ulexite (NaCaB5O6(OH)6·5(H2O)), extracted from the natural mineral, was added as a binder to give ceramic paper the necessary strength for its manipulation and catalytic use. Either La,Co or Ba,Co was incorporated in order to give ceramic paper the capability of trapping NOx and oxidizing soot particles. Structured catalysts were characterised by SEM, FTIR and XRD, and the mechanical properties were also determined. Lanthanum was deposited on ceramic fibres as La2O2CO3aggregates and barium as BaCO3filaments, being cobalt deposited as Co3O4flakes. Mechanical properties indicated that the ceramic paper obtained from natural ulexite proved to be stronger, though less flexible than those prepared using colloidal suspensions as a binder. Diesel soot oxidation activity was determined by TPO either adding or not 0.1% NO into the feeding stream. The thus prepared systems resulted in being active towards soot oxidation, being the value of maximum combustion rate 420 °C, which is within the temperature range of diesel exhaust gases.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238890,"idioma_id":4,"titulo":"Robot for weed species plant-specific management","resumen":"The rapid evolution of herbicide-resistant weed species has revitalized research in nonchemical methods for weed destruction. Robots with vision-based capabilities for online weed detection and classification are a key enabling factor for the specialized treatment of individual weed species. This paper describes the design, development, and testing of a modular robotic platform with a heterogeneous weeding array for agriculture. Starting from requirements derived from farmer insights, technical specifications are put forward. A design of a robotic platform is conducted based on the required technical specifications, and a prototype is manufactured and tested. The second part of the paper focuses on the weeding mechanism attached to the robotic platform. This includes aspects of vision for weed detection and classification, as well as the design of a weeding array that combines chemical and mechanical methods for weed destruction. Field trials of the weed detection and classification system show an accuracy of 92.3% across a range of weed species, while the heterogeneous weed management system is able to selectively apply a mechanical or chemical control method based on the species of weed. Together, the robotic platform and weeding array demonstrate the potential for robotic plant-species?specific weed management enabled by the vision-based online detection and classification algorithms.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238893,"idioma_id":4,"titulo":"Mixtures of Lightweight Deep Convolutional Neural Networks: Applied to Agricultural Robotics","resumen":"We propose a novel approach for training deep convolutional neural networks (DCNNs) that allows us to tradeoff complexity and accuracy to learn lightweight models suitable for robotic platforms such as AgBot II (which performs automated weed management). Our approach consists of three stages, the first is to adapt a pre-trained model to the task at hand. This provides state-of-the-art performance but at the cost of high computational complexity resulting in a low frame rate of just 0.12 frames per second (fps). Second, we use the adapted model and employ model compression techniques to learn a lightweight DCNN that is less accurate but has two orders of magnitude fewer parameters. Third, K lightweight models are combined as a mixture model to further enhance the performance of the lightweight models. Applied to the challenging task of weed segmentation, we improve the accuracy from 85.9%, using a traditional approach, to 93.9% by adapting a complicated pre-trained DCNN with 25M parameters (Inception-v3). The downside to this adapted model, Adapted-IV3, is that it can only process 0.12 fps. To make this approach fast while still retaining accuracy, we learn lightweight DCNNs which when combined can achieve accuracy greater than 90% while using considerably fewer parameters capable of processing between 1.07 and 1.83 fps, up to an order of magnitude faster and up to an order of magnitude fewer parameters.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238894,"idioma_id":4,"titulo":"Autonomous Sweet Pepper Harvesting for Protected Cropping Systems","resumen":"Abstract:In this letter, we present a new robotic harvester (Harvey) that can autonomously harvest sweet pepper in protected cropping environments. Our approach combines effective vision algorithms with a novel end-effector design to enable successful harvesting of sweet peppers. Initial field trials in protected cropping environments, with two cultivar, demonstrate the efficacy of this approach achieving a 46% success rate for unmodified crop, and 58% for modified crop. Furthermore, for the more favourable cultivar we were also able to detach 90% of sweet peppers, indicating that improvements in the grasping success rate would result in greatly improved harvesting performance.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238896,"idioma_id":4,"titulo":"A Late Pleistocene Guloninae (Carnivora, Mustelidae) from South America (Argentina, Entre R&iacute;os province), biogeographic implications","resumen":"The record of Guloninae presents mainly a Holarctic distribution, with only Eira barbara occurring in South America (SA). This lineage immigrated from Central America at least in the Pleistocene. The fossil record of Guloninae for SA is limited to a few known specimens of Eira from Late Pleistocene of Brazil. We report a new specimen of E. barbara (an upper carnassial) from Late Pleistocene of Entre Ríos, Argentina. We also discuss the taxonomic assignation of this new fossil and its paleoenvironmental relevance using Species Distribution Modeling (SDM). The new material comes from Ensenada Creek, Salto Ander Egg Formation, fromthe Late Pleistocene between 120 and 60 ky BP. The locality is farther south than its recent distribution, and SDM shows low suitability values for such area, which also indicates that the species is absent from this area in present time. The P4 is bigger and the protocone has a more anterior position relative to the paracone than that of recent specimens of E. barbara. This new fossil indicates that E. barbara had a wider distribution over the Late Pleistocene and, if our interpretation is correct, it has been present in SA at least since 120-60 ky BP. The presence of E. barbara in such a southern locality, together with other taxa recorded in this site and the associated geological and paleoenvironmental evidences, indicates warmer and more humid conditions, comparedwith the current conditions, which might have allowed a southern displacement of taxa more related to forested and tropical environments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238897,"idioma_id":4,"titulo":"Peduncle Detection of Sweet Pepper for Autonomous Crop Harvesting&mdash;Combined Color and 3-D Information","resumen":"This letter presents a three-dimensional (3-D) visual detection method for the challenging task of detecting peduncles of sweet peppers (Capsicum annuum) in the field. Cutting the peduncle cleanly is one of the most difficult stages of the harvesting process, where the peduncle is the part of the crop that attaches it to the main stem of the plant. Accurate peduncle detection in 3-D space is, therefore, a vital step in reliable autonomous harvesting of sweet peppers, as this can lead to precise cutting while avoiding damage to the surrounding plant. This letter makes use of both color and geometry information acquired from an RGB-D sensor and utilizes a supervised-learning approach for the peduncle detection task. The performance of the proposed method is demonstrated and evaluated by using qualitative and quantitative results [the area-under-the-curve (AUC) of the detection precision-recall curve]. We are able to achieve an AUC of 0.71 for peduncle detection on field-grown sweet peppers. We release a set of manually annotated 3-D sweet pepper and peduncle images to assist the research community in performing further research on this topic.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238898,"idioma_id":4,"titulo":"Trajectory tracking passivity-based control for marine vehicles subject to disturbances","resumen":"In this paper we present a dynamic model of marine vehicles in both body-fixed and inertial momentum coordinates using port-Hamiltonian framework. The dynamics in body-fixed coordinates have a particular structure of the mass matrix that allows the application of passivity-based control design developed for robust energy shaping stabilisation of mechanical systems described in terms of generalised coordinates. As an example of application, we follow this methodology to design a passivity-based controller with integral action for fully actuated vehicles in six degrees of freedom that tracks time-varying references and rejects disturbances. We illustrate the performance of this controller in a simulation example of an open-frame unmanned underwater vehicle subject to both constant and time-varying disturbances. We also describe a momentum transformation that allows an alternative model representation of marine craft dynamics that resembles general port-Hamiltonian mechanical systems with a coordinate dependent mass matrix.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238904,"idioma_id":4,"titulo":"Beyond genomic selection: The animal model strikes back (one generation)!","resumen":"Genome inheritance is by segments of DNA rather than by independent loci. We introduce the ancestral regression (AR) as a recursive system of simultaneous equations, with grandparental path coefficients as novel parameters. The information given by the pedigree in the AR is complementary with that provided by a dense set of genomic markers, such that the resulting linear function of grandparental BV is uncorrelated to the average of parental BV in the absence of inbreeding. AR is then connected to segmental inheritance by a causal multivariate Gaussian density for BV. The resulting covariance structure (&Sigma;) is Markovian, meaning that conditional on the BV of parents and grandparents, the BV of the animal is independent of everything else. Thus, an algorithm is presented to invert the resulting covariance structure, with a computing effort that is linear in the number of animals as in the case of the inverse additive relationship matrix.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238910,"idioma_id":4,"titulo":"Position Affects Performance in Multiple-Object Tracking in Rugby Union Players","resumen":"We report an experiment that examines the performance of rugby union players and a control group composed of graduate student with no sport experience, in a multiple-object tracking task. It compares the ability of 86 high level rugby union players grouped as Backs and Forwards and the control group, to track a subset of randomly moving targets amongst the same number of distractors. Several difficulties were included in the experimental design in order to evaluate possible interactions between the relevant variables. Results show that the performance of the Backs is better than that of the other groups, but the occurrence of interactions precludes an isolated groups analysis. We interpret the results within the framework of visual attention and discuss both, the implications of our results and the practical consequences.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238911,"idioma_id":4,"titulo":"Perception of Speed, Distance, and TTC of Familiar Objects","resumen":"It has been shown that knowing the size of an approaching object affects our perception of time-to-collision (TTC) in a manner similar to the way it affects perception of the physical speed of objects moving in the fronto-parallel plane. In this article, we present a series of experiments exploring the effect of object familiarity on the perception of speed and distance in the context of motion in depth (MID), and the interplay among these variables in the perception of TTC. Results of the first experiment show that object familiarity does not help human observers to discriminate the speed of MID. In the second experiment, we show that familiar size may be used to infer the relative distance among objects, in the context of MID, but not to make accurate estimations. Finally, we show that the relative TTCs do not follow the perceived relative distances obtained in the second experiment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238912,"idioma_id":5,"titulo":"Territorio, Elites y Redes Socio-Institucionales en la Provincia de Córdoba, Argentina, Hacia el siglo XX. Modelos en disputa, Industrialismo vs Agronegocios","resumen":"El análisis de la emergencia y consolidación de redes de distinta naturaleza y alcance asigna una importancia creciente dentro de los estudios territoriales. Diferentes autores consideran al territorio como un conjunto de relaciones políticas, económicas, sociales, culturales y ecológicas que se caracterizan como una red construida sobre una historia territorial.En este artículo se hace hincapié en la estructura espacial y económica en la región sur de la provincia de Córdoba, Argentina, con foco en la ciudad de Río Cuarto, identificando las redes socio-institucionales construidas por las élites dominantes y sus principales vínculos a través del tiempo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238913,"idioma_id":5,"titulo":"PREMEZCLA DE FECULA DE MANDIOCA PARA PASTAS. CARACTERÍSTICAS QUÍMICAS Y VIDA ÚTIL EN ANAQUEL","resumen":"El consumo de pastas es masivo, no existiendo variedad en premezclas para fideos libres de gluten. El objetivodel trabajo fue evaluar características químicas de fideos elaborados a partir de una premezcla para pastas confécula de mandioca, harina de maíz, leche, sal y goma xántica; y la vida útil en anaquel de la misma. Para conocerla composición centesimal y la digestibilidad de proteínas se recurrió a elaboración y cocción de fideos; para lavida útil se empaquetaron bolsas de premezcla y analizaron durante 12 meses de almacenamiento a temperatura yhumedad ambiente. Se obtuvieron valores elevados de cenizas, grasas, fibra dietaria total y carbohidratos, y bajosde proteínas; la digestibilidad de proteínas fue 92,72%. El ANOVA reportó diferencia significativa para humedada los diferentes meses, con disminución en el tiempo; no se detectaron microorganismos de interés sanitario. Lapremezcla resultó apta para consumo humano según Código Alimentario Argentino.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238914,"idioma_id":5,"titulo":"De Investigación en Turismo","resumen":"El artículo publicado presenta los primeros resultados y la metodología seguida para llevar adelante el Proyecto de Investigación Bienal de la SeCTyP de la UNCUYO, que se denomina'Los impactos del Turismo en Tupungato: una mirada sustentable'","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238916,"idioma_id":4,"titulo":"Modelado de la Producci&oacute;n de Biomasa Microalgal en un Fotobiorreactor de Burbujeo Anular y Configuraci&oacute;n Variable","resumen":"The results of the modeling of empirical data relative to marine microalgae cultures (Phaedactylum tricornutum and Tetraselmis sp.) in a pilot photobioreactor of two vertical concentric tubes with bubbling in the annular&nbsp;space, are presented. The geometry of this reactor switches between two configurations involving different&nbsp;culture volume and different hydrodynamics. The effect on biomass productivity that provokes an increasing&nbsp;in volume of culture at the expense of diminishing the capture of light energy has been analyzed. Finally, to&nbsp;consider the influence of shadowing of the cells on the biomass increment at medium and high&nbsp;concentration, a model is proposed with involvement of the exponential growth kinetic equation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238917,"idioma_id":4,"titulo":"Impact of the laminar flow on the electrical double layer development","resumen":"As soon as a liquid comes into contact with a solid, physicochemical reactions occur at the solid-liquid interface to form an electrical double layer. According to the classical theory, it is assumed that the laminar flow has no impact on the global rate of the physicochemical reactions (Kf). However, recent studies have shown that this assumption is not consistent with the experimental results. It seems that Kf is impacted by the flow velocity of the liquid. The aim of this work is to compare the experimental behavior with the numerical simulation taking this variation into account.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238918,"idioma_id":4,"titulo":"Flow electrification of liquids in rectangular channels - Comparison of different theoretical models","resumen":"This paper deals with flow electrification phenomenon of liquids in channels of rectangular cross section. Different theoretical models are described and compared. For all the models it is assumed that the flow and the diffuse layer are fully developed. The space charge density conveyed by the flow is computed. First, two cases are examined in the case of weak space charge density, the exact rectangular channel solution is compared with the approximate solution of two parallel planes. This comparison shows a rather small difference between the two models. Then, in the case of two parallel planes assumption, the charge conveyed is computed without any hypothesis on the magnitude of the space charge density and compared to the solution obtained for a weak space charge density commonly assumed. This comparison shows a big difference between the two models concerning the determination of the space charge density on the wall and therefore the zeta potential [1].","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238924,"idioma_id":5,"titulo":"Políticas públicas de promoción de plantaciones forestales comerciales: los casos del Valle de Calamuchita (Córdoba) y de la región de Virasoro (Corrientes)","resumen":"Este trabajo identifica y evalúa el impacto de los factores que causaron la disparidad en el desarrollo forestal basado en plantaciones generadas mediante la aplicación de diferentes regímenes de promoción en dos regiones: la cuenca forestal del noreste de la provincia de Corrientes y la del Valle de Calamuchita, provincia de Córdoba. Se aplicó el método comparativo,relacionando las causas que determinan el grado de desarrollo forestal mediante indicadores cuantitativos. Se recolectó la información mediante cuestionarios, entrevistas semiestructuradas y recopilación bibliográfica. Se analizó y discutió el marco normativo, las políticas aplicadas, las condiciones ecológicas y los modelos de manejo forestal, los aspectos económicos y los principales actores. Estas variables se relacionaron con la evolución de la superficie forestada (total y anual), la extracción de rollizos, el grado de desarrollo de las empresas de la cadena y cantidad de puestos de trabajo directos generados. Se concluye que estos indicadores permitieron caracterizar y confirmar la disparidad en el desarrollo alcanzado por las dos regiones, aportando un primer indicio de que la aplicación de un único objetivo de promoción en todo el territorio nacional acentúa las ventajas comparativas regionales. Los criterios para el diseño y aplicación de nuevos instrumentos de promoción deberían abordar tres aspectos: los paradigmas de promoción, sus instrumentos y el alcance territorial de las intervenciones del Estado.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238926,"idioma_id":5,"titulo":"?Tutorías de fin de carrera. El caso de Ingeniería Forestal en la Universidad Nacional de La Plata?","resumen":"En este articulo caracterizamos los estudios forestales en Argentina y damos cuenta del devenir curricular de la carrera de Ingeniería Forestal (IF) en la Universidad Nacional de La Plata (UNLP). Describimos y analizamos una experiencia de tutoria de fin de carrera desarrollada en la Facultad de Ciencias Agrarias y Forestales, en el marco del Programa de Mejora de la Enseñanza de Ingeniería Forestal, Ingeniería en Recursos Naturales e Ingeniería Zootecnista (PROMFORZ)","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238927,"idioma_id":4,"titulo":"TRUE BUGS (HEMIPTERA: HETEROPTERA) ASSOCIATED WITH SOYBEAN (GLYCINE MAX (L.) MERR.) IN SOUTHERN CONE","resumen":"","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238929,"idioma_id":5,"titulo":"Estrategias de gobierno para gestionar el riesgo de desastres: planificación, diseño organizacional y comunicación","resumen":"¿Es la naturaleza culpable de las grandes pérdidas generadas a causade tornados, inundaciones, terremotos? ¿O existe algún factor humanocontrolable que haría posible reducir los daños y la pérdida de vidashumanas ante los desastres? Y, si es así, ¿los gobiernos pueden haceralgo cuando la naturaleza nos juega una mala pasada? ¿A través de quéestrategias de gobierno puede gestionarse el riesgo de desastres? Elpresente artículo se propone analizar la importancia de gestionar el riesgode desastres a través de la definición de estrategias de gobierno según elparadigma de la gobernanza, como planificación, diseño organizacionaly construcción de equipos, y comunicación del riesgo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238930,"idioma_id":5,"titulo":"La gestión de redes cambia toda la gestión: los procesos de cambio organizacional en los gobiernos locales a partir del uso de las redes sociales digitales","resumen":"Este artículo analiza los cambios que se están produciendo en las administraciones públicas locales en América Latina desde un enfoque organizacional, a partir del uso de las redes sociales digitales que se obtuvo de las evidencias que aportó el estudio Gobernautas y ciudadanos: los gobernantes latinoameri canos y la gestión de redes sociales (2016), en los distritos de más de un millón de habitantes en la región. Se aborda el análisis a partir de cuatro componentes organizativos: articulación estratégica, diseño organizacional, gestión del talento humano (construcción de equipos y liderazgo) y los procesos de regulación, evaluación y control. Los resultados evidencian un sólido y cada vez más visible avance en la institucionalización de los sectores de gestión de la comunicación en los gobiernos locales, que se refleja en la existencia formal de áreas de comunicación en todas las ciudades; la existencia de instancias de coordinación entre los ámbitos de la comunicación general y la comunicación digital y la gestión en equipo de la comunicación, con preponderancia de recursos humanos propios. Existen puestos de trabajo y perfiles específicos de la comunicación digital, pero aún con un bajo nivel de institucionalización.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238931,"idioma_id":5,"titulo":"El desarrollo de talentos como estrategia para abordar los nuevos desafíos en la administración pública","resumen":"Las administraciones públicas abordan a diario nuevos desafíos a partir de una agenda de innovaciones en torno a la profesionalización y democratización de la gestión pública, el uso estratégico de nuevas tecnologías, el desarrollo de la gobernanza, la participación ciudadana, el gobierno abierto. Estos desafíos difícilmente puedan abordarse y llevarse adelante sin un enfoque estratégico e integrado de la gestión del talento, que ponga foco en el valor del trabajo de las personas que integran y viabilizan el funcionamiento del EstadO.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238934,"idioma_id":5,"titulo":"Politicas publicas de promoción de plantaciones forestales: los casos del Valle de Calamuchita (Córdoba) y de la región de Virasoro (Corrientes)","resumen":"Este trabajo identifica y evalúa el impacto de los factores que causaron la disparidad en el desarrollo forestalbasado en plantaciones generadas mediante la aplicación de diferentes regímenes de promoción en dosregiones: la cuenca forestal del noreste de la provincia de Corrientes y la del Valle de Calamuchita, provincia deCórdoba. Se aplicó el método comparativo, relacionando las causas que determinan el grado de desarrolloforestal mediante indicadores cuantitativos. Se recolectó la información mediante cuestionarios, entrevistassemiestructuradas y recopilación bibliográfica. Se analizó y discutió el marco normativo, las políticas aplicadas,las condiciones ecológicas y los modelos de manejo forestal, los aspectos económicos y los principales actores.Estas variables se relacionaron con la evolución de la superficie forestada (total y anual), la extracción de rollizos,el grado de desarrollo de las empresas de la cadena y cantidad de puestos de trabajo directos generados. Seconcluye que estos indicadores permitieron caracterizar y confirmar la disparidad en el desarrollo alcanzado porlas dos regiones, aportando un primer indicio de que la aplicación de un único objetivo de promoción en todo elterritorio nacional acentúa las ventajas comparativas regionales. Los criterios para el diseño y aplicación denuevos instrumentos de promoción deberían abordar tres aspectos: los paradigmas de promoción, susinstrumentos y el alcance territorial de las intervenciones del Estado.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238935,"idioma_id":4,"titulo":"Seasonality effects over the ecological aquaculture of the native zooplanktivorous fish from South America Odontesthes bonariensis","resumen":"Ecological aquaculture systems consider the natural and social environments in which they are situated in thesearch to contribute to environmental sustainability. In South America, the aquaculture of the nativezooplanktivorous fish Odontesthes bonariensis (?pejerrey?) has some constraints that could be overcome by applyingextensive culture systems following an ecosystemic approach. This study represents the first attempt todevelop ecological aquaculture in the region. An experiment of extensive cage culture was carried out in La Saladade Monasterio Lake to answer how seasonal changes, both in physico-chemical and zooplankton features, affectthe performance of pejerrey culture. Three successive rearing trials were carried out in spring, summer and autumn.The cages were stocked with pejerrey; whereas others (controls) were left without fish. Lake zooplanktonabundance, biomass and species composition were different among seasons, with maximum abundance meanvalues during summer and maximum biomass mean values during spring. The zooplankton abundance foundin cages without fish was higher than that registered in cages with fish, but no differences in species compositionamong those cages were detected. The pejerrey showed selective feeding habits throughout the entire experiment,and they fed mostly on copepods and cladocerans of N0.7 mm during spring and summer, especiallyafter reaching 4 cm in total length, and on smaller copepods and cladocerans during autumn. The contributionof the different sizes of zooplankton to the gut contents was related to availability and to fish size, and the accessto bigger zooplankton appeared to be a critical factor to promote better growth performance. The bigger fishwere obtained in spring, when zooplankton biomass was maximum in the lake with greater representation oflarge cladocerans, with final fish weight eight times higher than that obtained in summer and fifty times greaterthan that obtained in autumn. The production obtained in spring was one and two orders of magnitude higherthan that found in summer and autumn. The multiple linear regressions selected support the inference that seasonaltemperature and zooplankton variations have effects on pejerrey growth in floating cages. Pampean lakescould be suitable environments to support pejerrey ecological aquaculture, and spring emerges as the better seasonto start an extensive culture that takes advantage of the zooplankton composition and dynamics.Statement of relevance to commercial aquaculture: Alternative tool to overcome constraints in pejerrey culture","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238936,"idioma_id":4,"titulo":"Microplastics in gut contents of coastal freshwater fish from R?o de la Plata estuary","resumen":"The presence of microplastics (MPs) in gut contents of coastal freshwater fish of the Rio de la Plata estuary was studied. Samples were taken in six sites where 87 fish belonging to 11 species and four feeding habits were captured. Presence of MPs was verified in the 100% of fish. The fibres represented the 96% of MPs found. The number of MPs in gut contents was significantly higher close to sewage discharge. There was not found relationship between number of MPs and fish length, weight or feeding habit. The spatial differences in mean number of MPs in fish observed in this study, suggest that environmental availability of MPs could be of great importance to explain the differences found among sampling sites analysed. This work represents the first study about the interaction between MPs and aquatic organisms in this important estuarine ecosystem of South America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238937,"idioma_id":4,"titulo":"Potential antioxidant peptides produced from whey hydrolysis with an immobilized aspartic protease from Salpichroa origanifolia fruits","resumen":"An aspartic protease from Salpichroa origanifolia fruits was successfully immobilized onto an activated support of glutaraldehyde agarose. The immobilized enzyme presented higher thermal stability than the free enzyme from 40 °C to 50 °C and high reusability, retaining 54% of the initial activity after ten cycles of the process. Whey protein concentrates (WPC) were hydrolyzed with both free and immobilized enzyme, reaching a similar degree of hydrolysis of approximately 6?8% after 20 h. In addition, the immobilized derivate hydrolyzed &#945;-lactalbumin protein with a higher affinity than &#946;-lactoglobulin. The hydrolysate was ultra-filtrated, and the fractions were evaluated for antioxidant activities with the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity method. The fraction containing peptides with a molecular mass below 3 kDa demonstrated a strong radical quenching effect (IC50: 0.48 mg\/ml). These results suggest that hydrolyzed WPC could be considered as a promising source of natural food antioxidants for the development of functional food.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238938,"idioma_id":5,"titulo":"HISTORIA DEL DERECHO HUMANO AL AGUA. 'EL RÍO ATUEL TAMBIÉN ES PAMPEANO'","resumen":"El presente trabajo pretende analizar la historia del surgimiento del derecho humano al agua y su consagración normativa -a nivel internacional-, y desde ese punto de partida,se busca abordar la larga lucha del pueblo y Gobierno de la Pampa, sobre el derecho que les asiste en el uso compartido de las aguas de un río interprovincial.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238943,"idioma_id":5,"titulo":"Aplicación del sistema de valor a la planificación del desarrollo de las cadenas forestoindustriales de álamo ubicadas en el norte de la Patagonia Argentina","resumen":"El objetivo del trabajo fue identificar las restricciones para el desarrollo del sistemaproductivo de álamo (Populus spp) localizado en los valles irrigados de Norpatagonia (Argentina). Los datos provinieron de fuentes primarias (entrevistas y un taller) y secundarias (publicaciones), los que permitieron describir el sistema forestal, actores y eslabones existentes en el territorio, sus interacciones, los problemas percibidos y las posibles líneas de acción para superarlos, enmarcado en el sistema de valor de Porter. Los aspectos analizados fueron: producción, concentración de empresas, encadenamientos, mercados, aspectos sociales, culturales einstitucionales. Se identificaron tres cadenas: Alto Valle, Valle Medio y Valle de Conesa e Inferior del río Negro. Se concluyó que la impulsión del desarrollo debe hacerse a partir del diseño y articulación de políticas territoriales consensuadas mediante una red de actores públicos y privados: empresas, INTA, universidades, CONICET, entes interprovinciales, asociaciones empresariales y organismos sectoriales nacionales y provinciales ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238944,"idioma_id":5,"titulo":"Políticas públicas de promoción de plantaciones forestales comerciales: los casos del Valle de Calamuchita (Córdoba) y de la región de Virasoro (Corrientes","resumen":"Estetrabajo identificay evalúa el impacto de los factores que causaron la disparidad en el desarrolloforestal basado en plantaciones generadas mediante la aplicación de diferentesregímenes de promoción en dos regiones: la cuenca forestal del noreste de laprovincia de Corrientes y la del Valle de Calamuchita, provincia de Córdoba. Se aplicó el métodocomparativo, relacionando las causas que determinan el grado de desarrollo forestal mediante indicadorescuantitativos. Serecolectó la información mediante cuestionarios, entrevistas semiestructuradasy recopilación bibliográfica. Se analizó y discutió el marco normativo, las políticasaplicadas, las &nbsp;condiciones ecológicas ylos modelos de manejo forestal, los aspectos económicos y los principalesactores. Estas variables se relacionaron con la evolución de lasuperficie forestada (total y anual), la extracción derollizos, el grado de desarrollo de las empresas de la cadena y cantidad depuestos de trabajo directos generados. Se concluye que estos indicadorespermitieron caracterizar y confirmar la disparidad en el desarrollo alcanzadopor las dos regiones, aportandoun primer indicio de que la aplicación de un único objetivo de promoción en todo el territorionacional acentúa las ventajas comparativas regionales. Los criterios para eldiseño y aplicación de nuevos instrumentos de promoción deberían abordar tresaspectos: los paradigmas de promoción, sus instrumentos y el alcanceterritorial de las intervenciones del Estado.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238945,"idioma_id":4,"titulo":"OH- and O3-initiated atmospheric degradation of camphene: Temperature dependent rate coefficients, product yields and mechanisms","resumen":"Gas-phase rate coefficients for the reactions of OH and O3 with camphene have been measured over the temperature range 288?311 K using the relative rate method. The experiments were carried out in an environmental chamber using long-path FTIR spectroscopy to monitor the reactants. Room temperature rate coefficients (in cm3 per molecule per s) of k(camphene+OH) = (5.1 +\/- 1.1)x  1011 and k(camphene+O3) =(5.1  +\/- 1.1)x  1019 were obtained for the OH and O3 reactions, respectively. The temperature dependence of the reactions are best fit by the Arrhenius expressions (in cm3 per molecule per s)k(camphene+OH)= (4.1  +\/- 1.2)x  1012 exp[(754 +\/-  44)\/T] for the OH reaction and k(O3+camphene)= (7.6  +\/- 1.2)x 1018 exp[(805  +\/-  51)\/T] for the O3 reaction. To the best of our knowledge, this is the first report ofthe temperature dependencies for the reactions of OH and O3 with camphene. In addition, product studies have been performed at (298  +\/- 2) K and 760 Torr of synthetic air for the reaction of OH + camphene in the absence and presence of NOx, and for O3 molecules + camphene at (298  +\/- 2) K and750 Torr of synthetic air. For the OH reaction the following molar product yields were obtained: acetone(10  +\/- 2)% and (33 +\/- 6)%, and formaldehyde (3.6  +\/- 0.7)% and (10  +\/- 2)% in the absence and presence of NOx, respectively. Formaldehyde with a molar yield of (29  +\/- 6)% was the only product uniquely identified and quantified for the O3 reaction.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238946,"idioma_id":4,"titulo":"Mechanisms and product distribution of the O3-initiated degradation of (E)-2-heptenal, (E)-2-octenal and (E)-2-nonenal","resumen":"The O3-molecule initiated degradation of three 2-alkenals (E)-2-heptenal, (E)-2-octenal, and (E)-2-nonenal has been investigated in a 1080 L quartz-glass environmental chamber at 298 &plusmn; 2 K and atmospheric pressure of synthetic air using in situ FTIR spectroscopy to monitor the reactants and products. The experiments were performed in the absence of an OH scavenger. The molar yields of the primary products formed were glyoxal (49 &plusmn; 4) % and pentanal (34 &plusmn; 3) % from the reaction of (E)-2-heptenal with O3, glyoxal (41 &plusmn; 3) % and hexanal (39 &plusmn; 3) % from the reaction of (E)-2-octenal with O3, and glyoxal (45 &plusmn; 3) % and heptanal (46 &plusmn; 3) % from the reaction of (E)-2-nonenal with O3. The residual bands in the infrared product spectra for each of the studied reactions are attributed to 2-oxoaldehyde compounds. Based on the observed products, a general mechanism for the ozonolysis reaction of long chain unsaturated aldehydes is proposed, and the results are compared with the available literature data.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238947,"idioma_id":4,"titulo":"Kinetics of t-2-hexenyl acetate and 4-methyl-3-penten-2-one with OH and Cl radicals at 298 K and atmospheric pressure.","resumen":"Rate coefficients for the reactions of hydroxyl radicals and chlorine atoms with two biogenic volatile organic compounds as (E)-2-hexenyl acetate and 4-methyl-3-penten-2-one have been determined at 298 K and atmospheric pressure. The decay of the organics was followed using a chromatograph with a flame ionization detector (GC-FID) and the rate constants were determined using a relative rate method.Rate coefficients are found to be (in cm3 molecule1 s1): k1(OH þ (E)-2-hexenylacetate) ¼ (6.88 ± 1.41)  1011, k2(Cl þ (E)-2-hexenyl acetate) ¼ (3.10 ± 1.13)  1010, k3(OH þ 4-methyl-3-penten-2-one) ¼ (1.02 ± 0.20)  1010 and k4(Cl þ 4-methyl-3-penten-2-one) ¼ (2.66 ± 0.90)  1010 at 298 K. This is the first kinetic experimental study for these reactionsstudied under atmospheric pressure. The rate coefficients are compared with previous determinationsfor other unsaturated and oxygenated compounds and reactivity trends are presented. Products identification studies were performed using solid-phase microextraction (SPME) method employing on-fiber products derivatization with o-(2,3,4,5,6-pentafluorobenzyl) hydroxylamine hydrochloride using gas chromatograph with a mass spectrometer detector (GC-MS) for the reactions studied. In addition, atmospheric lifetimes of the unsaturated compounds studied are estimated and compared with other tropospheric sinks for these compounds","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238948,"idioma_id":5,"titulo":"?\tDiagnóstico fenotípico de Staphylococcus pseudointermedius resistentes a la meticilina: estudio de laboratorio como apoyo a la práctica en la clínica privada en piodermias caninas.","resumen":"Se procesaron en el laboratorio de bacteriología 96 muestras de piel de caninos con diagnóstico de piodermia  para confirmar por pruebas fenotípicas la presencia de Staphylococcus pseudintermedius resistentes a la meticilina  así como su comportamiento frente a  los antimicrobianos más utilizados en la práctica clínica. Los hisopados se procesaron mediante métodos convencionales de cultivo, identificación de especie y pruebas de sensibilidad antimicrobiana. A partir del aislamiento de estafilococos en medio de cultivo selectivo, y consiguiente cultivo puro,  se realizaron las pruebas  bioquímicas de coagulasa,  Vogues Proskauer, fermentación de trehalosa, manitol y maltosa, hidrólisis de la arginina y l-pirrolidonilarilamidasa. La sensibilidad se evaluó por el método de difusión en agar y se realizó el D-test para detectar resistencia constitutiva\/inducible a clindamicina. Los antimicrobianos probados fueron oxacilina, trimetroprima sulfametoxazol, eritromicina, clindamicina, cloranfenicol, ciprofloxacina, minociclina, rifampicina y vancomicina. Staphylococcus pseudintermedius se identificó en 91 animales (94,8%). La resistencia a la meticilina utilizando el disco de oxacilina para su detección fue del 34%. Entre los antibióticos probados, los que presentaron mayor resistencia fueron: trimetroprima sulfametoxazol 61\/67%, eritromicina 59\/64,4% y clindamicina 56\/ 61,5%.  Este estudio mostró que la identificación fenotípica de Staphylococcus pseudintermedius así como la resistencia a la meticilina y otros antimicrobianos de uso frecuente en las piodermias caninas con el antibiograma por difusión, tienen valor para la prescripción  prudente de antimicrobianos y promueve el uso responsable de los mismos en medicina veterinaria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238949,"idioma_id":4,"titulo":"Brewers yeast, Saccharomyces cerevisiae, enhances attraction of two invasive yellowjackets (Hymenoptera: Vespidae) to dried fruit and fruit powder.","resumen":"The German yellowjacket, Vespula germanica, and common yellowjacket, Vespula vulgaris, are native and invasive pests of significant economic, environmental, and medical importance in many countries. There is a need for the development and improvement of attractive baits that can be deployed in traps to capture and kill these wasps in areas where they are a problem. Yellowjackets are known to feed on fermenting fruit, but this resource is seldom considered as a bait due to its ephemeral nature and its potential attractiveness to non-target species. We analyzed the headspace volatiles of dried fruit and fruit powder baits with and without Brewer?s yeast, Saccharomyces cerevisiae, using gas chromatography-mass spectrometry, and we field tested these baits for their attractiveness to yellowjackets in Argentina. The addition of yeast to fruit powder enriched the volatile composition. Dried fruit and fruit powder baits on their own were hardly attractive to yellowjackets, but the addition of yeast improved their attractiveness by 9- to 50-fold and surpassed the attractiveness of a commercial heptyl butyrate-based wasp lure. We suggest that further research be done to test additional varieties and species of yeasts. A dried fruit or fruit powder bait in combination with yeast could become a useful tool in the management of yellowjackets.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238954,"idioma_id":5,"titulo":"Desestimando demandas en la orientación de los niños a la adopción en los juzgados de familia en la conurbación de Buenos Aires (Argentina)","resumen":"Este artículo analiza, desde un enfoque etnográfico, las diferentes 'técnicas de persuasión' que los agentes de los juzgados de familia del conurbano bonaerense despliegan en la orientación de los niños a la adopción. Esas técnicas buscan, por un lado, desalentar los pedidos de reintegro de sus niños por parte de los miembros de los grupos domésticos y, por otro, animar a los niños a formar nuevos lazos sociales con personas que -eventualmente- podrían tornarse sus responsables. Este repertorio de  técnicas se constituye recíprocamente junto a la participación de los niños y de sus familiares en esos procesos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238955,"idioma_id":4,"titulo":"Multi-resolution anisotropy studies of ultrahigh-energy cosmic rays detected at the Pierre Auger Observatory","resumen":"We report a multi-resolution search for anisotropies in the arrival directions of cosmic rays detected at the Pierre Auger Observatory with local zenith angles up to 80o and energies in excess of 4 EeV (4&nbsp;×&nbsp;1018 eV). This search is conducted by measuring the angular power spectrum and performing a needlet wavelet analysis in two independent energy ranges.  Both analyses are complementary since the angular power spectrum achieves a better performance in identifying large-scale patterns while the needlet wavelet analysis,  considering the parameters used in this work,  presents a higher efficiency in detecting smaller-scale anisotropies, potentially providing directional information on any observed anisotropies.   No deviation from isotropy is observed on any angular scale in the energy range between 4 and 8 EeV. Above 8 EeV, an indication for a dipole moment is captured; while no other deviation from isotropy is observed for moments beyond the dipole one.  The corresponding p-values obtained after accounting for searches blindly performed at several angular scales, are 1.3&nbsp;×&nbsp;10&#8722;5 in the case of the angular power spectrum,  and 2.5&nbsp;×&nbsp;10&#8722;3 in the case of the needlet analysis.  While these results are consistent with previous reports making use of the same data set, they provide extensions of the previous works through the thorough scans of the angular scales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238959,"idioma_id":5,"titulo":"Colonización y ocupación no planificada.  La mercantilización de la tierra  agrícola en Misiones  (1920-2000)","resumen":"Los diferentes procesos de poblamiento que se han dado en Misiones durante el siglo XX determinaron su configuración espacial y territorial. El objetivo de este artículo es comparar a través de dos estudios de caso las formas de constitución del mercado de tierras en la colonización privada y en la ocupación no planificada. Para el primero, se focalizará en la&nbsp; ?Compañía Colonizadora Eldorado?, describiendo las etapas que caracterizaron la subdivisión y venta de parcelas de las colonias Puerto Rico, Montecarlo y Eldorado (Alto Paraná misionero). Para el segundo, se considerarán casos de ocupación de tierras pertenecientes a empresas extractivistas en el nordeste provincial (departamentos San Pedro y Guaraní) y su posterior conversión en extensiones fiscales, sustraídas parcialmente del mercado y cuya subdivisión se lleva a cabo de acuerdo al régimen de mensura particular.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238971,"idioma_id":5,"titulo":"De sombreros y cosmeticos: industrias embellecedoras del cuerpo en la Exposición Nacional de 1871","resumen":"Las industrias dedicadas al cuidado y embellecimiento corporal tuvieron un lugar relevante en la Exposición Nacional de 1871 en Córdoba. La ponencia analiza las mismas enfocándose en la sombrerería y la cosmética, trazando relaciones entre éstas y la retratística de la época.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238987,"idioma_id":4,"titulo":"Food sovereignty and consumer sovereignty: two antagonistic goals?","resumen":"The concept of food sovereignty is becoming an element of everyday parlance indevelopment politics and food justice advocacy. Yet to gain widespread civil societyacceptance the idea of food sovereignty and its demands have to be able to coexistwith already well-anchored principles of consumer sovereignty. The aim of this article isto examine the different sets of demands that the two ideals of sovereignty bring about,analyse in how far these different demands can be made compatible with each otherand explain why consumers have to adjust their food demands to seasonal productionvariability to promote food sovereignty and so secure future autonomy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238988,"idioma_id":4,"titulo":"Can conservation agriculture improve crop water availability in an erratic tropical climate producing water stress? A simple model applied to upland rice in Madagascar","resumen":"Family farms in the tropics mainly rely on rainfed agriculture. Water availability is limited to rainfall and is one of the main constraints to crop productivity. Conservation agriculture (CA) is promoted as an alternative that, among other functions, enhances water infiltration and limits evaporation from the soil thanks to a mulch of crop residues left on the soil surface. These functions are assumed to reduce the water availability constraint by limiting water stress during crop growth. But the variability of rainfall distribution combined with the wide range of agroecological conditions and the variety of crop husbandries in the tropics makes it difficult to evaluate the efficiency of mulching. The aim of this study was to capture the variability through a simple modeling approach using the crop growth model PYE-CA, which requires a limited set of parameters and a virtual experiment (VE). We applied our approach to a case study of upland rice in the Lake Alaotra region in Madagascar, where rainfall distribution is highly variable. The VE used a 17-year series of weather data with a range of soil water conditions, sowing dates, and growth and yield limitations that cover the variability of agroecological conditions and management systems in the study area. The VE revealed that variable successions of wet and dry episodes during the rainy season resulted in both water stress and an increase in deep drainage. In the majority of conditions simulated, enhancing water infiltration through CA mainly increased water loss through drainage. However, better water infiltration may also reduce the production risks involved in early sowing or crop intensification, thereby offering new opportunities to farmers. As an alternative to time consuming and labor intensive experimentation, we propose a suitable modeling approach to identify the main drivers of rainfall × crop interactions that could be extrapolated to other regions in the tropics.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238989,"idioma_id":4,"titulo":"Combining farm typology and yield gap analysis to identify major variables limiting yields in the highland coffee systems of Llano Bonito, Costa Rica","resumen":"Yield variability in space and time is a well-known phenomenon in the highland coffee production systems of Costa Rica. Our objective was to systematically unravel variations and gaps in yields due to the combined effects of farm resources and major production variables in a region of premium quality highland coffee. We surveyed 40 coffee producing farms varying in size from small to large in Llano Bonito, Costa Rica to examine their diversity based on their resources. We further conducted an agronomic diagnosis and yield estimates in 97 individual measuring plots in 63 coffee fields over two cropping years (2013?2014 and 2014?2015). We categorized farm diversity through a resource endowment typology built by combining direct observation with the use of multivariate analysis and clustering techniques. This resulted in four farm types: large farms depending on external labour (Type 1, 25%), large farms with livestock (Type 2, 20%), small farms dedicated to coffee (Type 3, 38%), and small farms with an off-farm income (Type 4, 17%). We then analysed coffee yield variability and yield gaps through a boundary line approach. The mean yields for two cropping years fluctuated between 2.5 ± 0.18 and 1.6 ± 0.12 t ha&#8722;1 on farm types 1 and 2 respectively. Though the yields did not differ strongly across farm types, there was a weak tendency (p = 0.10) towards yield variability between study years. The combined use of farm typology and yield gap analysis revealed multiple farm&#8208;specific production variables that were significantly related to gaps in attainable yields. For any intervention to improve and stabilize yields in the future, the heterogeneity of farm orientation, management practices, production geographical context and soil properties must be given proper attention and integrated into crop, shade tree and soil management practices.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238990,"idioma_id":4,"titulo":"&lsquo;To and fro&rsquo; the southern Andean highlands (Argentina and Chile): Archaeometric insights on geographic vectors of mobility","resumen":"The Andes mountain range is one key physiographic feature of South America with the potential to have acted as a barrier and corridor for human societies. The goal of this paper is to assess from where and how were the highlands utilized during the last 2000 years, which is a key period witnessing the development of productive economies and changes in the organization of mobility. We develop a regional case study focused on the highland wetland Laguna del Diamante (3300 masl), which is a highly productive ecosystem only accessible during summer. This case is based on a multidisciplinary approach combining: a) geochemical characterization of obsidian sources located in the highlands and artifacts; b) isotopic approach to ranges of paleomobility of individuals by means of 87Sr\/86Sr; and c) stylistic study of ceramic assemblages. The two main obsidian types from the highlands have restricted and decaying spatial distribution, suggesting that these archaeological distributions track part of human circuits of mobility instead of indirect transport acquisition. Their archaeological distribution is heavily skewed towards the western Andean slope. We present strontium isotope values for four teeth and bone samples from two individuals recovered in the area, which are interpreted in reference to a preliminary baseline of biologically available strontium. We infer that these individuals had ranges of paleomobility systematically connecting the western slope with the highlands. The analysis of the ceramic assemblages shows that most of the diagnostic sherds can be assigned to styles that have distributional cores in the Central Valley of Chile up until the time of Inca presence, while only a minimum portion of the sample can be assigned to distributional cores on the eastern slope. By integrating the patterns in the transport of obsidian and ceramic artifacts and the paleomobility of individuals, we find support for the existence of dominant access to the highlands from the western Andean slope. A GIS-based analysis of the seasonality of precipitation shows that the western slope presents more pronounced and drier summer months, providing a context that contributes to explain these patterns. These results contradict previous interpretations suggesting that the archaeological record from the highlands is more directly tied to human groups inhabiting the eastern lowlands during most of the year. Beyond the geographic debate, this issue has an impact on the subsistence organization of the incoming groups, on the socio-economic role of the highlands, and on the demographic contexts leading to trajectories of economic intensification in both Andean slopes. This research contributes to build a framework for comparative research on human use of highland environments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238991,"idioma_id":4,"titulo":"Archaeological discontinuities in the southern hemisphere: A working agenda","resumen":"This introductory overview presents the frame of research and general goals of the special volume ?Archaeological Discontinuities: Comparative Frameworks for the southern hemisphere?. We begin by deconstructing archaeological discontinuities in terms of time and space in order to assess what sort of past phenomena are we dealing with when assessing discontinuities in different scales. It is one of our main contentions that we need theory and data connecting discontinuities as recorded on different analytical scales, thereby contributing to evaluate often-undescribed mechanisms that produce archaeological discontinuities. On this basis, we face the key task of deconstructing archaeological discontinuities from ?top to bottom?, moving from the averaged material record that is visible in archaeological scale towards the short-term human decisions and interactions that, when occurring cumulatively, produce those discontinuities. Nevertheless, while an understanding of the short-term behavioral mechanisms and social agency behind discontinuities is necessary, it is certainly not sufficient for building a frame in which to make sense of the long-term record.Archaeological discontinuities recorded at different spatial scales require different explanatory mechanisms that can be connected hierarchically. The most productive analytical take here would be to move from the bottom to the top, building from the site or local scales to the regional and continental levels. This strategy provides a solid frame for assessing the genesis of discontinuities at different scales by disentangling the incidence of sampling deficiencies in the field, the selection of samples for chronometric dating, taphonomic biases, the reorganization of mobility and technology, local and regional abandonments, and actual demographic changes.We finish by selecting a few issues that we consider worthy of systematic comparative attention in the years to come. These issues impinge on different levels of theory and methods and can only be pursued with an interdisciplinary focus that encompasses not only archaeology but also ethnography, genetics, linguistics, paleoclimatology and paleoecology. We are convinced that there is much to learn from a comparative perspective in terms of structural similitudes in historical processes across regions and continents. The conceptual structure of a number of debates from South America, Africa, and Australia on is remarkably similar, notwithstanding important differences in terms of chronology and tempo. We look forward to international joint endeavors such as this one that help to formalize questions and data-collecting strategies for the southern drylands and beyond.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238995,"idioma_id":5,"titulo":"Cine para ver en el cine, cine para ver en casa. La fragmentación de las prácticas de visionado","resumen":"Durante las últimas décadas, el cine se despegó de las salas y se volvió ubicuo en nuestras vidas cotidianas, siendo consumido en muy diversas situaciones y espacios. En este artículo se explora la fragmentación de las prácticas de visionado entre el cine y el hogar, indagando en las posibles relaciones de esta forma preferencial, en el cine o en el hogar. Asimismo, se enfoca en particular el modo en que el cine argentino se reubica dentro de este contexto de transformaciones. En cuanto a la metodología, el trabajo emplea una serie de materiales empíricos como entrevistas y datos estadísticos del sector, para analizar las prácticas y estrategias de visionado de los espectadores.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238997,"idioma_id":5,"titulo":"NIÑOS, NUEVAS TECNOLOGÍAS Y GÉNERO: HACIA LA DEFINICIÓN DE UNA AGENDA DE INVESTIGACIÓN","resumen":"La relación entre las Tecnologías de la Información y de la Comunicación (TIC) con diversos aspectos de la vida cotidiana contemporánea constituye un fructífero campo dentro de los estudios sociales. Las constantes indagaciones sobre las formas de uso, de socialización, de significación y de representación ubican a las TIC como centro de grandes interrogantes de la investigación en ciencias sociales en el siglo XXI. Este artículo tiene como objetivo componer una agenda para la investigación de las TIC en relación con el género, los niños, las niñas y los juegos. Si bien estos ejes han sido estudiados, las intersecciones y las articulaciones que identificamos en los últimos proyectos nos abrieron nuevas perspectivas para la indagación. ¿Qué hacen los niños y las niñas con los dispositivos con los que se vinculan? ¿De qué formas el género se constituye como una variable interviniente en las dinámicas, personajes, acciones y roles que se pueden (o no) asumir durante las interacciones lúdicas? En el artículo se presentan los diferentes elementos de una agenda de trabajo con los principales ejes, problemas, hipótesis y metodologías sobre las cuales se proyectan nuestros trabajos actuales y futuros  como forma de contribuir al campo en el que se enmarcan.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":238998,"idioma_id":5,"titulo":"Programa CyTMA2. Inclusión y formación de investigadores en la Universidad Nacional de La Matanza","resumen":"El Programa CYTMA2 (Programa de Investigación Científica,Desarrollo y Transferencia de Tecnologías e Innovaciones) tuvo su origen en laResolución N° 16 del 4 de marzo de 2004 del Honorable Consejo Superior de laUNLaM. Con ella se creaba el Programa CYTMA, que luego se discontinuó. En el año2010, se crea el Programa PICE (Programa de Investigaciones en CienciasEconómicas) que tenía como objetivo formar docentes investigadores e incorporarlosen proyectos propios del Departamento.Este Programa fue el embrión que propició el relanzamiento del Programa CYTMA,bajo la nueva denominación CYTMA2, aprobado por el Honorable Consejo Superiorde la UNLaM a través de las Resoluciones N° 103 y 104 del 01\/12\/2011.Estas Resoluciones aprobaban un Reglamento de Administración de Fondos yRendición de Cuentas para los Programas PROINCE y CYTMA2, así como la normativapara la presentación de proyectos en el marco de ambos programas.La implementación del programa CYTMA 2 permitió la inclusión y formación denuevos investigadores. Solamente en el Departamento de Ciencias Económicasingresaron 230 nuevos investigadores, en 46 proyectos que fueron presentados al31\/12\/2016.Esta inclusión permitió que más de 100 docentes obtuvieran la categoría V porprimera vez en el marco del programa de incentivos de la SPU.En la presentación se mostraron los resultados de la implementación del Programa ylas características del mismo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239002,"idioma_id":4,"titulo":"Quantitative geomorphology applied to fluvial dynamic in Aviles and Moneta basins, Tierra Del Fuego, Southern Argentina","resumen":"The morphometric characteristics of the Moneta river basin are compared to those of the Avilés river basin. Both are located in the north of the province of Tierra del Fuego in Argentina, and they also have their catchment area in the same range: the Sierras del Bosque; runoff on the NE-oriented slopes forms the Avilés river basin, while runoff on the SE slopes forms the Moneta river basin. The analysis was made in two different scales: the first as a general scale of the basin, and the second as the catchment sector (upper, middle and lower). The quantitative analysis was applied in order to know the behavior of these two fluvial systems. For the analysis, a cartographic basis scale to 1: 20,000 was used, which was made on a mosaic of images from Google Earth®; the altimetric information was obtained throughout a digital elevation model of 45-m spatial resolution SRTM45 (Shuttle Radar Topographic Mission). The indices used were Rr, Rb, Ish and Dd to characterize the geological and geomorphological context, and Rl, Re, If, Ct and Ca to infer the behavior of the runoff in the catchment. It was established that the Moneta river basin reaches 6 in order of hierarchy; its main channel is 65.52 km long. The Re determines an elongated basin. The Ct obtained in the basin is 0.96, whereas the sub-basin level was identified to a maximum value of the O3-SM-10 (1.46). The Dd is low (1.94 km\/km2), which is directly proportional to the intensity of rainfall and the slopes of the area considered. The comparison, made at the same scale, between basins determines specific fluvial characteristics of each sector (upper, middle and lower).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239003,"idioma_id":5,"titulo":"Dinámica geomorfológica y urbanización en áreas periurbanas. Norte de Bahía Blanca, Argentina","resumen":"La expansión de la ciudad de Bahía Blanca ha intervenido gran parte del espacio periurbano norte con la consecuente modificación del paisaje natural y en particular el trazado de la red hidrográfica. Los mapas geomorfológicos son instrumentos que posibilitan el análisis evolutivo y facilitan la visualización de los procesos y formas de la superficie. En este contexto, su elaboración mediante software SIG facilita el análisis de los cambios en el entorno natural debido al avance de la urbanización. El objetivo del trabajoes estudiar las implicancias mutuas entre la dinámica geomorfológicay el proceso de urbanización en el periurbano norte de la ciudad de Bahía Blanca. La identificación de geoformas y procesos se realizó a partir de la lectura de documentos geológicos del área, análisis visual de imágenes satelitales de alta resolución (2009 y 2015) y control de campo. Se implementó una base de datos geográfica mediante ArcGIS 10® que posibilita el análisis evolutivo y la elaboración de cartografía temática digital. A partir del análisis cuali-cantitativo de la cartografía se identificaron áreas naturalesmodificadas por la urbanización y sectores de la nueva trama urbanamás propensos a ser afectados por la dinámica hidrogeomorfológica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239008,"idioma_id":5,"titulo":"Variaciones microclimáticas en el interior y exterior del bosque de caldén (Prosopis caldenia), Argentina","resumen":"Clima y vegetación son variables del espacio físico que poseen una relación dinámica y de interdependencia. La flora modifica los elementos climáticos y da lugar a un microclima cuya caracterización está en función de las condiciones climáticas regionales y de la estructura de la vegetación. El objetivo del trabajo fue comparar las variaciones climáticas (interior y exterior) del bosque de caldén en la Reserva Provincial Parque Luro. Se  analizaron y compararon estadísticamente los datos de temperatura, humedad relativa, velocidad, dirección del viento y precipitación de dos estaciones meteorológicas para el 2012. Se demostró la influencia del bosque en los parámetros climáticos y se comprobó que las variaciones mayores se dieron en la velocidad del viento, la temperatura diaria y las precipitaciones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239015,"idioma_id":5,"titulo":"Variaciones microclimáticas en el interior y exterior del bosque de caldén (Prosopis caldenia), Argentina","resumen":"Clima y vegetación son variables del espacio físico que poseen una relación dinámica y de interdependencia. La flora modifica los elementos climáticos y da lugar a un microclima cuya caracterización está en función de las condiciones climáticas regionales y de la estructura de la vegetación. El objetivo del trabajo fue comparar las variaciones climáticas (interior y exterior) del bosque de caldén en la Reserva Provincial Parque Luro. Se  analizaron y compararon estadísticamente los datos de temperatura, humedad relativa, velocidad, dirección del viento y precipitación de dos estaciones meteorológicas para el 2012. Se demostró la influencia del bosque en los parámetros climáticos y se comprobó que las variaciones mayores se dieron en la velocidad del viento, la temperatura diaria y las precipitaciones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239019,"idioma_id":4,"titulo":"Efect of ozone on bacterial contamination of fruits during postharvest handling","resumen":"Cleaning is said to be one of the most important stages during postharvest handling due to its relationship with shelf life and food safety. At this stage, chlorine is usually added to water, bringing about consequent negative environmental effects. The aim of this study was to evaluate the effect of ozone, as an alternative to chlorine, on bacterial contamination of fruits during postharvest handling. An ozonation equipment from IMEB (Institute of Evolutionary and Biological Medicine) Rio Cuarto was used, incorporating a flow rate of 8.15 grO3.h-1 in water. Escherichia coli ATCC 25922 was exposed to ionized water at different times, 0; 5; 10; and 20 minutes.  Subsequently, the number of cells surviving ozone exposure was evaluated. To this end, after the dilutions were made, samples from three consecutive dilutions were plated in triplicate on each Agar. They were incubated at 37°C during 48 hours and eventually the surviving colonies were counted. The dilution used was the one in which the number of colonies were from 30 to 300, determining the average of such dilution. It was found that the surviving cells were significantly different (p&#61502;0.05) 100; 62,5; 39 and 17% in 0, 5, 10 and 20 minutes of exposure to ozonated water, respectively. The results indicate an important bactericidal effect on E. coli. However, it should be necessary to focus on further studies that reduce the time exposure of fruits to package cleaning.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239021,"idioma_id":4,"titulo":"In vitro effect of edible coatings for fruits on the growth of Botrytis cinerea colonies","resumen":"Strawberries are non-climacteric fruits that exhibit high respiratory activity and high perishability. They have a very short postharvest life of 7 to 10 days if stored at 2°C and 90% humidity. This characteristic results from their respiratory rate, their susceptibility to mechanical damage and the invasion of some pathogenic fungi. During the postharvest treatment of strawberries, Botrytis cinerea is the most common organism causing significant fruit losses. To reduce these losses, different compounds are used as edible coatings (EC). They constitute a continuous, thin matrix that is structured around fruits. The objective of the study was to determine the in vitro effect of edible coatings on the growth of Botrytis colonies. The strawberries used were a variety of Albion, presenting colonies of fungi, identified as Botritis. Portions were extracted from the area of bacterial growth and they were eventually placed in Petri dishes with Agar, adding each treatment at the rate of 2.5 ml. per box with 9 replicates. They were then incubated at 30°C for 48 hours. The treatments were three EC: Aloe Vera, Stevia and Calendula, as well as their control without coating. The results show significant differences (p&#61502;0,05) among the treatments with lower colonies counts: Stevia and Calendula (0 and 0.22 average colonies), with respect to Aloe and the control that had 1 to 1.1 colonies average per plate. This demonstrates the positive effect of ECs based on Stevia and Calendula on the control of Botritis during postharvest periods.S","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239022,"idioma_id":4,"titulo":"In vitro effect of edible coatings for fruits on  the growth of Penicilliun sp colonies","resumen":"Peaches are climacteric fruits that have a post-harvest life ranging from 1 to 5 weeks if kept in proper storage. One of the main factors of post-harvest loss is rot caused by fungi, such as Penicillium sp. In order to reduce these post-harvest losses, different compounds are used as edible coatings (EC). They constitute a continuous, thin matrix, which is structured around the fruits. The objective of the study was to determine the in vitro effect of three edible coatings on the growth of fungal colonies responsible for postharvest rot of fruits. Elegant Lady peaches presenting fungal colonies identified as Penicillium were used. Portions were extracted from the area of bacterial growth and they were eventually placed in Petri dishes with Agar, adding each treatment at the rate of 2.5 ml per box with 9 replicates. They were then incubated at 30°C during 48 hours. The treatments consisted of three EC: Aloe Vera, Stevia and Calendula, as well as their control without coating. The results showed significant differences (p&#61502;0,05) among the EC and the control. The average number of colonies was of 1; 1,1; 2 and 19,1, for Stevia, Calendula, Aloe Vera and control, respectively. There were no differences among coatings. However, the treatments with better impact were Stevia and Calendula, while Aloe presented twice as many colonies. This demonstrates the positive effect of EC on post-harvest control of Penicillium.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239023,"idioma_id":4,"titulo":"Efect of ozone on fungal contamination of fruits during postharvest handling","resumen":"To obtain a good quality fruit, the conditioning stage requires a cleaning process. The water used for washing commonly has disinfectants, which can generate adverse effects on the environment and health. Ozone can be a sustainable alternative to the packing of fruits. The objective of this study was to evaluate the in vitro effect of ozonated water on fungi contaminating fruits. An ozonation equipment from IMEB (Institute of Evolutionary and Biological Medicine) Rio Cuarto was used, incorporating a flow rate of 8.15 grO3.h-1 in water. All the peaches used contained fungi, and the material corresponding to Penicillium sp. was isolated. These samples were diluted in sterile water, exposed to the ozonated water and maintained in constant agitation to maintain a homogeneous solution. Samples were extracted at different times: 1; 5 and 15 minutes and a control without ozone. They were plated in triplicate on Agar plates and were incubated at 30°C during 48 hours. Afterward, the sum of the diameters of the Penicillium colonies was recorded on each plate. The average diameter of colonies was 7.4; 4,3; 1.9 and 1.7 cm for the control; 1; 5 and 15 minutes respectively. Although there were no statistically significant differences, the reduction in the diameter of colonies of the fungus with regards to C was 42, 74 and 77.3%. These preliminary results could indicate an effect of ozone in water on Penicillium sp.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239024,"idioma_id":5,"titulo":"Diagnóstico molecular de hemocromatosis hereditaria.","resumen":"Introducción: la HH es un desorden autosómico recesivo del metabolismo del hierro con aumento de su absorción y reserva. Es una de las enfermedades más comunes en la población caucásica y presenta una prevalencia variable entre diferentes grupos étnicos. Puede ser el resultado de defectos en el gen HFE (tipo 1) o de defectos no asociados con éste. El gen HFE fue clonado, identificándose una mutación puntual G&#8594;A resultando en una sustitución de cisteína por tirosina (C282Y), reportada en alrededor del 80% de los pacientes estudiados con HH tipo 1 en ciertas regiones de Europa. Otras dos mutaciones en HFE fueron descriptas; un cambio de histidina por ácido aspártico en el aminoácido 63 (H63D) hallada en un 15-20% y un cambio de serina por cisteína en la posición 65 (S65C) hallada con muy baja frecuencia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239026,"idioma_id":5,"titulo":"Mutaciones en el dominio quinasa de BCR\/ABL en pacientes con Leucemia Mieloide Crónica (LMC) resistentes al tratamiento,","resumen":"La LMC es una enfermedad clonal de la stem cell hematopoyética. Es causada por la translocación t(9;22), que da origen al gen de fusión bcr\/abl que codifica una tirosinquinasa (TK) constitutivamente activa. Imatinib fue el primer inhibidor de TK (ITK) aprobado para el tratamiento de la LMC en 2001. Posteriormente fueron aprobados otros ITK como Dasatinib y Nilotinib y más tarde fueron desarrollados Bosutinib y Ponatinib. Si bien el tratamiento con ITK es altamente efectivo, un tercio de pacientes que inician terapia con Imatinib experimentan resistencia al tratamiento manifestándose como falta o pérdida de respuesta o como progresión de la enfermedad. Aproximadamente la mitad de los pacientes con resistencia a los ITK tienen mutaciones en el dominio kinasa de BCR\/ABL.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239027,"idioma_id":5,"titulo":"La información básica para el estudio de la Geografía del Comercio Internacional. Los mapas de la organización mundial del Comercio (Primera Parte).","resumen":"Los diferentes mapas muestran la diversidad de información que brinda la OMC, constituyéndose  en  una  de  las  bases  fundamentales  de  datos  para  la  descripción  de  la geografía de los intercambios y el análisis de sus principales tendencias. En este primer informe se presentan los que refieren a los miembros, a los  grupos de negociación  y a los   acuerdos   regionales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239028,"idioma_id":5,"titulo":"Necesidad del uso de inhibidor de ribonucleasa para el diagnóstico molecular de muestras con eosinofilia.","resumen":"Los eosinófilos (Eo) son granulocitos polimorfonucleares que se diferencian a partir de una célula madre hematopoyética en la médula ósea. Dentro de sus funciones protectoras se encuentra la producción de radicales libres y liberación del contenido de sus gránulos citoplasmáticos. Las proteínas que éstos contienen son responsables de muchas funciones proinflamatorias y citotóxicas. Dentro de los gránulos específicos se encuentran la Proteína básica principal, Proteína catiónica eosinofílica (ECP), Neurotoxina derivada de eosinófilos (EDN), Peroxidasa de eosinófilo, hidrolasas lisosomales e histaminasa. La  ECP (RNAsa 3) y EDN (RNAsa 2) pertenecen a la superfamilia RNasa A y la función de estas enzimas es hidrolizar y degradar el RNA.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239029,"idioma_id":4,"titulo":"Effect of Crack Patterns on the Stress Distribution of Hard Chromium Coatings Under Sliding Contact: Stochastic Modeling Approach","resumen":"In this work, the influence of different crack arrangementsin the stress distribution of hard chromium coatings was determined.Three parameters for position and length of the cracks for two different types of coatings were probabilistically modelled based on measured SEM images. Probability density functions for those parameters were obtained tocharacterise each kind of coating. A 2D finite element model of thecoating in contact with a rigid disc was developed, modelling crackswith elliptical shapes. A Monte Carlo method was used to simulate differentcrack distributions for each kind of coating, and values of stressand strains in the domain were obtained. Both the J-integral and thestress intensity factors were taken as comparative parameters of theresults. Coatings which statistically present larger quantities ofshorter cracks have lower values of J-integral and stress intensityfactors, and, therefore, distribute stresses better than those withlow density of longer cracks. pp061401-061401-10","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239030,"idioma_id":5,"titulo":"PERFIL DE MUTACIONES CAUSANTES DE TROMBOCITEMIA ESENCIAL (TE) Y MIELOFIBROSIS PRIMARIA (MFP)","resumen":"Policitemia Vera (PV), Trombocitemia Esencial (TE) y Mielofibrosis Primaria (MFP), constituyen un grupo de enfermedades hematológicas malignas que se caracterizan por una producción aumentada de uno o más tipos celulares sanguíneos. La etiología molecular está relacionada con mutaciones que producen activación de la vía de señalización intracelular JAK\/STAT. El descubrimiento de la mutación JAK2V617F ha representado un gran avance en el conocimiento de la patogénesis y el diagnóstico de estas patologías. Posteriormente, fueron identificadas mutaciones en el exón 10 del receptor de trombopoyetina (MPL) y más recientemente  inserciones o deleciones en el exón 9 del gen de Calreticulina (CALR).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239031,"idioma_id":4,"titulo":"Flooding effects on grassland species composition in the Azul creek basin (Argentina).","resumen":"From a hydrological point of view, the characteristic of the water behaviour in catchments so depressed as the Azul creek basin (centre of Buenos Aires province, Argentina) is water accumulation above the land surface. Thus, water on the ground does not have a single runoff direction, but moves in a disorderly, indefinite and unpredictable way. Considering that periodic floods are a typical disturbance of the region, the objective of this study is to analyse, under field conditions, the transformative effect of prolonged flooding on floristic composition, taking into account the different vegetation patches and their relative position over the relief, the chemical characteristics and the groundwater fluctuation, and some edaphic properties in each site.Vegetation samplings were performed during three consecutive springs, when the grassland was on different hydrological conditions due to very different rainfall precedent histories. A digital terrain model of the study area was built and a flow accumulation map was created from it. Pits were dug to describe edaphic variables and shallow wells were drilled for monitoring the groundwater characteristics. Flooding, in relation with surface and groundwater dynamics and soil characteristics, is the factor that determines and promotes the differentiation among sites that are relatively close, contiguous and even topographically in almost identical positions. So, some patches of vegetation get their differentiation through the limiting conditions of their soils, while others receive greater influence from the hydrodynamics to which they are subject. Thus, in this study it becomes evident how certain stands are floristically homogenised or differentiated over time according to their flooding conditions and, hence, according to the area from which they receive surface and groundwater flow. Also, results corroborate the way the water regime determines the structure and heterogeneity of plant communities in such environments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239032,"idioma_id":5,"titulo":"INVESTIGACIÓN HIDROGEOLÓGICA EN UN VALLE SERRANO MEDIANTE LA APLICACIÓN DE MÉTODOS GEOELÉCTRICOS","resumen":"e realizó unaexploración geofísica mediante sondeos eléctricos verticales ytomografía de  resistividad eléctrica en una zona ubicada alsudoeste de la ciudad de Tandil. El sector corresponde a un valle depequeñas dimensiones en la cual se halla emplazada una cancha degolf y un barrio residencial. El objetivo del trabajo ha sidodeterminar los espesores del sector acuífero y evaluar las reservasde agua para aumentar la extracción y el abastecimiento a todo elcomplejo. La zona de estudio presenta la misma problemática que granparte del área de Tandil, en la cual la roca del basamento seencuentra muy cercana a la superficie produciendo una situación muycompleja para la obtención de agua subterránea. Mediante laexploración realizada se logró complementar los resultadosobtenidos mediante sondeos eléctricos verticales y tomografía deresistividad eléctrica, con lo cual se pudo definir la geometríadel acuífero y las zonas más adecuadas para nuevas perforaciones.Por otra parte, y a partir de los resultados de la exploración, serealizaron cálculos de la recarga y reservas de agua subterránea locual permitió evaluar los caudales diarios a extraer.p { margin-bottom: 0.25cm; line-height: 115%; }","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239033,"idioma_id":5,"titulo":"Laboratorio portátil de escritorio para la enseñanza de la electrónica","resumen":"La forma de impartir enseñanza debe cambiar para satisfacer a la nueva generación de estudiantes que quiere aprender por vías no tradicionales y empleando nuevas tecnologías.Los estudiantes de esta generación se consideran dueños de las Tecnologías deInformación y Comunicación (TICs), poseen una asombrosa capacidad de adaptación en toda actividad que las implique, y ostentan un nivel de decodificación visual o iconográfica mayor que las generaciones anteriores, por lo que a veces rechazan los modos tradicionales de exposición En este trabajo se presentauna propuesta de estrategia metodológica basada en el aprendizaje experiencial de Kolb para ser aplicado a la enseñanza de la Electrónica Básica mediante la implementación de laboratorios portátiles de escritorio en diferentes asignaturas de la carrera Ingeniería en Electrónica (UNCa).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239034,"idioma_id":5,"titulo":"Conocimientos, creencias y actitudes de los profesionales de la salud de los servicios de obstetricia de hospitales generales de la CABA, respecto del modelo de causales para la realización de abortos no punibles","resumen":"El trabajo apunta a indagar conocimientos, creencias y actitudes de los profesionales de la salud sobre el modelo de causales en torno al aborto no punible (ANP).El problema de investigación que orienta el trabajo puede resumirse en el siguiente interrogante: ¿Cuáles son los conocimientos,creencias y actitudes que construyen y expresan los profesionales de la salud de diferentes hospitales generales de CABA, respecto del modelo de causales (para la interrupción del embarazo) que rige en nuestro país y su aplicación?La razón por la cual consideramos este interrogante como un problema relevante, se centra en que los conocimientos, las creencias y actitudes de los profesionales, en referencia al modelo de causales, puede llegar a constituir un facilitador o un obstáculo para el acceso de las mujeres a la práctica del aborto.En la legislación argentina el aborto es punible, excepto cuando está contemplado en las causales de no punibilidad. El Código Penal establece cuáles son las circunstancias en las que el aborto no es punible; pero de muchas maneras este amparo legal es cercenado. Aparecen resistencias representadas por el desconocimiento, o conocimientos erróneos del modelo de causales, falta de protocolización y unificación de los procedimientos que derivan en la burocratización y medicalización del acceso de las mujeres al ANP.Cuando una mujer se dirige a un profesional de la salud solicitando ayuda y su intervención, es menester que sean preservados el derecho a la salud, a la información, a la autonomía de las mujeres, de modo que la exigencia de dictámenes de otros profesionales puede resultar un requisito obstaculizador, sin conexión con las necesidades de la mujer. Dicho requerimiento viola el derecho a la igualdad y a la equidad, a la vez que supone, por parte del Estadorepresentado en la institución hospitalaria, un ejercicio abusivo ensu facultad de regulación. Ciertos requisitos se traducen en procesosburocráticos que dilatan el acceso a la interrupción legal del embarazo y ?que incluso pueden derivar en una prohibición implícita del aborto? .La toma de conciencia del poder que los profesionales ejercen enel dispositivo asistencial, supone un necesario desplazamientode ese lugar de autoridad hacia una orientación clara sobre lasdistintas causales que podrían aplicarse en cada situación. Elloimplica poner en el centro de la escena la voz de las mujeres queconsultan. De este modo es la mujer quien mide el riesgo que estádispuesta a correr y el rol de los profesionales será el de acompa-ñar una decisión informada. Dicho acompañamiento, en tanto redsocial de apoyo, se conforma en el seno de una institución (Erviti,2005). En este sentido, aspectos de la cultura organizacional enjuego serán tenidos en cuenta a la hora de visualizar la conformaciónde los conocimientos, creencias y actitudes de los profesionales.Como estos perciben y se perciben respecto de la tarea, definecuestiones en relación a la eficiencia y a la flexibilidad dentro de lainstitución que integran. La cultura de una institución de salud ?esun sistema de conocimientos profesionales, expectativas, creenciasy supuestos inconscientes?, visibles o no para el equipo detrabajo, ?fuertemente influidos por la estructura, la tecnología y elambiente laboral?...","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239036,"idioma_id":5,"titulo":"La Intermunicipalidad en Los Municipios Metropolitanos Argentinos","resumen":"El objetivo de este artículo es analizar la dinámica de las iniciativas intermunicipales que se originaron en gobiernos locales integrantes de áreas metropolitanos en Argentina. El mismo se enmarca en una investigación global que contempló el estudio de las 255 iniciativas intermunicipales de todo tipo en las últimas tres décadas. En el país, a diferencia de otros países latinoamericanos, no se prevén en las leyes la especificidad del fenómeno metropolitano. Por ello, este arreglo emerge como el único que permitiría resolver la manifiesta desconexión entre las políticas ejecutadas, las competencias legales y la configuración político-administrativa de estos territorios. Los resultados nos permiten observar el pequeño número de iniciativas; su desarrollo en áreas metropolitanas de distinto tamaño poblacional; su concentración en pocas provincias; la existencia de microrregiones y mancomunidades en número equivalente; su debilidad estructural; su volatilidad temporal; su baja institucionalización; la participación de organismos internacionales cooperantes en su desarrollo; y su impacto sobre la agenda pública, entre otros.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239047,"idioma_id":4,"titulo":"Air quality loss in urban centers of the Argentinean dry Chaco: wind and dust control  as two scientifically neglected ecosystem services","resumen":"Dry Chaco is one of the most active agriculture frontiers, which imposes trade-offs and synergies with ecosystem services (ES). Most studies analyze real or potential supply of ES associated to land use change; but they usually neglect ES social demands. Interviews of inhabitants of small urban centers in the Dry Chaco.revelaled that windbreak and dust protection are high valued ES in towns within agricultural context. The absence of such perception in forest-context urban centers, and the seasonal patterns of precipitation, wind speed and land cover validate the reality of such demand. Loss of air quality ?as an agricultural disservice- is a socially demanded ES so far ignored in the environmental research agenda, which should be reversed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239048,"idioma_id":4,"titulo":"Differences in production, carbon stocks and biodiversity outcomes of land tenure regimes in the Argentine Dry Chaco","resumen":"Rising global demand for agricultural products results in agricultural expansion and intensification, with substantial environmental trade-offs. The South American Dry Chaco contains some of the fastest expanding agricultural frontiers worldwide, and includes diverse forms of land management, mainly associated with different land tenure regimes; which in turn are segregated along environmental gradients (mostly rainfall). Yet, how these regimes impact the environment and how trade-offs between production and environmental outcomes varies remains poorly understood. Here, we assessed how biodiversity, biomass stocks, and agricultural production, measured in meat-equivalents, differ among land tenure regimes in the Dry Chaco. We calculated a land-use outcome index (LUO) that combines indices comparing actual vs. potential values of ´preservation of biodiversity´ (PI), ´standing biomass´ (BI) and ´meat production´ (MI). We found land-use outcomes to vary substantially among land-tenure regimes. Protected areas showed a biodiversity index of 0.75, similar to that of large and medium-sized farms (0.72 in both farming systems), and higher than in the other tenure regimes. Biomass index was similar among land tenure regimes, whereas we found the highest median meat production index on indigenous lands (MI = 0.35). Land-use outcomes, however, varied more across different environmental conditions than across land tenure regimes. Our results suggest that in the Argentine Dry Chaco, there is no single land tenure regime that better minimizes the trade-offs between production and environmental outcomes. A useful approach to manage these trade-offs would be to develop geographically explicit guidelines for land-use zoning, identifying the land tenure regimes more appropriate for each zone.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239049,"idioma_id":4,"titulo":". Bird diversity and its relationship with hábitat characteristics in High Andean Puna","resumen":"High Andean peatbogs are key functional units in the dry Puna region. They are functional wetlands with a main role in conserving local biodiversity, including bird communities. We surveyed bird communities from 18 peatbogs located in Argentina Puna from Jujuy, Salta and Catamarca provinces, to know their species composition, the change in species richness among peatbogs, and to explore the relationship between landscape and microhabitat variables with bird biodiversity. In the summer season of 2014 and 2015 we registered a total of 60 species belonging to 21 families. Peatbogs ranged from six to 20 species, Bright-rumped Yellow-finch Sicalis uropygialis, Ash-breasted Sierra Finch Phrygilus plebejus, Golden-spotted Ground Dove Metriopelia aymara and Puna Miner Geositta punensis presented higher Relative Importance Index. The change in bird species composition among peatbogs showed a nested structure. Bird richness and abundance were correlated with peatbog shape and distance to nearest peatbog. The present study shows that high Andean peatbogs from Argentina support a diverse avifauna correlated with some characteristics of landscape and microhabitat, with more bird´s diversity and abundance in peatbogs that are less isolated,  spatially associated with lakes and have  irregular shape.Key-words: Andean peatbogs, Argentine Puna, bird communities, biodiversity, nestedness, multivariate analysis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239050,"idioma_id":4,"titulo":"Opportunities drive the global distribution of protected areas","resumen":"Background. Protected areas, regarded today as a cornerstone of nature conservation, result from an array of multiple motivations and opportunities. We explored at global and regional levels the current distribution of protected areas along biophysical, human, and biological gradients, and assessed to what extent protection has pursued (i) a balanced representation of biophysical environments, (ii) a set of preferred conditions (biological, spiritual, economic, or geopolitical), or (iii) existing opportunities for conservation regardless of any representation or preference criteria. Methods. We used histograms to describe the distribution of terrestrial protected areas along biophysical, human, and biological independent gradients and linear and nonlinear regression and correlation analyses to describe the sign, shape, and strength of the relationships. We used a random forest analysis to rank the importance of different variables related to conservation preferences and opportunity drivers, and an evenness metric to quantify representativeness. Results. Wefind that protection at a global level is primarily driven by the opportunities provided by isolation and a low population density (variable importance D 34.6 and 19.9, respectively). Preferences play a secondary role, with a bias towards tourism attractiveness and proximity to international borders (variable importance D 12.7 and 3.4, respectively). Opportunities shape protection strongly in 'North America & Australia-NZ' and 'Latin America & Caribbean,' while the importance of the representativeness of biophysical environments is higher in 'Sub-Saharan Africa' (1.3 times the average of other regions). Discussion. Environmental representativeness and biodiversity protection are top priorities in land conservation agendas. However, our results suggest that they have been minor players driving current protection at both global and regional levels. Attempts to increase their relevance will necessarily have to recognize the predominant opportunistic nature that the establishment of protected areas has had until present times.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239051,"idioma_id":4,"titulo":"Modelling beta diversity of aquatic macroinvertebrates in High Andean wetlands","resumen":"Central Andean Highlands represent a singular environment characterized by various extremeconditions. Among them, peatbogs are exceptional marshy habitats scattered throughout this aridand harsh area. In an effort to understand the patterns of beta diversity, we sampled the benthicmacroinvertebrates of thirteen peatbogs and related the biological distance with ecologicaldistance using the GDM (Generalized Dissimilarity Modelling) approach. Variables analyzedwere altitude, geographical distance, physical and chemical parameters of the water. A coefficientbased on the ordering properties of count data, from the perspective of both sites and taxa, wasused to measure the compositional similarity between samples. The most frequent taxa were:Hyallela, Simuliidae, Andesiops, Austrelmis, Podonominae, Protallagma, Trichocorixa,Orthocladiinae and Glossiphonidae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239052,"idioma_id":4,"titulo":"Land-Use Redistribution Compensated for Ecosystem Service Losses Derived from Agriculture Expansion, with Mixed Effects on Biodiversity in a NW Argentina Watershed","resumen":"Areas of land abandonment and agriculture expansion usually differ in location and associated environmental characteristics; thus, land-use redistribution affects the provision of ecosystem services and biodiversity conservation. In a subtropical region undergoing land redistribution patterns characteristic of Latin America, we estimated 20-year changes in food production, aboveground carbon stocks and soil erosion due to land cover change, and the potential effects of such redistribution of forests on the diversity of birds and mammals. Between 1986 and 2006, despite only 0.3% of net forest cover change, 7% of the total area (c. 280000 has) switched between forest and non-forest covers. Food production increased by 46%, while the estimated ecosystem services changed by less than 10%. Forests carbon remained stable, with gains in montane humid forests compensating for losses in lowlands. Modeled soil erosion increased but sediment accumulation at the watershed bottom remained stable. The responses of birds and mammals to forests redistribution differed and were stronger in birds. Due to the strong responses of birds to forest loss, lowland bird communities might be especially threatened by current land-use trends. Results suggest that land redistribution associated with the adjustment of agriculture towards soils suitable for mechanized agriculture can help mitigate associated losses in ecosystem services and biodiversity, but species and supporting services depending on easily converted ecosystems require appropriate landscape management practices","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239053,"idioma_id":5,"titulo":"Proyecto: Turismo Social Educativo. Inclusión y Bienestar de niños de sectores sociales vulnerables, en el Municipio de Avellaneda","resumen":"p { margin-bottom: 0.25cm; direction: ltr; color: rgb(0, 0, 0); line-height: 120%; }p.western { font-family: 'Liberation Serif','Times New Roman',serif; font-size: 12pt; }p.cjk { font-family: 'Noto Sans CJK SC Regular','Times New Roman'; font-size: 12pt; }p.ctl { font-family: 'FreeSans','Times New Roman'; font-size: 12pt; }a.cjk:visited {  }a:link { color: rgb(0, 0, 255); }a.western:link {  }a.ctl:link {  }El presente trabajo presenta losavances, desafíos y conclusiones referidos al proyecto ?TurismoSocial Educativo. Inclusión y Bienestar de niños de sectoressociales vulnerables, en el Municipio de Avellaneda?, que seenmarca en el Programa de Apoyo a la Investigación en losObservatorios (PAIO) de la Universidad Nacional de Avellaneda(UNDAV).El objetivo general del proyectoconsistió en implementar un programa de turismo social dirigido aniños de sectores sociales vulnerables de Avellaneda, desde unenfoque educativo, para promover su bienestar social y complementarlos contenidos curriculares abordados en los Centros EducativosMunicipales (CEM) de la localidad de Avellaneda.Como parte de las actividades quelos mismos proponen, se realizan salidas didácticas, las cuales sonmuy valoradas, pero que desde la óptica del acceso igualitario abienes culturales no generan un reconocimiento de los participantescomo sujetos depositarios de un derecho al turismo.Algunos de los disparadores parala realización de este proyecto, fueron  pensar que el desarrolloterritorial nos lleva a plantearnos cuestiones implícitas en estasituación. Turismo urbano, relacionado con turismo social y acceso abienes. La ?salida?, la excursión, no es suficiente hasta que nose conectan los puntos de salida y llegada. Cuáles son lasrelaciones de poder, lucha y contención que se dan en un Estado queincluye, pero que a la vez oculta.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239054,"idioma_id":5,"titulo":"Comunidad originaria Itapirú trabajando por la conservación de orquídeas nativas","resumen":"Resumen:El proyecto ?Comunidad Originaria Itapirú: trabajando por la conservación de orquídeas nativas? -desarrollado en el marco del Programa de Fortalecimiento a las Actividades de Extensión (PROFAE) de la Universidad Nacional de Misiones-, se lleva a cabo en conjunto con alumnos, docentes, no docentes, graduados de la Facultad de Ciencias Forestales (UNaM), viveristas de Eldorado ?localidad de Misiones- como así también con la participación  del asentamiento aborigen  ?Comunidad originaria Itapirú?.El objetivo fundamental es apoyar a la comunidad aborigen mencionada en el trabajo de conservación de recursos naturales y su consecuente generación de ingresos económicos a través de actividades que se realizaron en distintos viveros  de la ciudad de Eldorado y en la Comunidad Originaria Itapirú localizada en El Soberbio (Misiones).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239055,"idioma_id":4,"titulo":"Chlamydia trachomatis neither exerts deleterious effects on spermatozoa nor impairs male fertility","resumen":"Chlamydia trachomatis is the most prevalent sexually transmitted bacterial infection. However, whether Chlamydia trachomatis has a negative impact on sperm quality and male fertility is still controversial. Herein, we report the effects on sperm quality of the in vitro exposure of spermatozoa to Chlamydia trachomatis, and also the effects of male genital infection on male fertility using an animal model. Human and mouse sperm were obtained from healthy donors and cauda epididimys from C57BL\/6 mice, respectively. Highly motile human or mouse spermatozoa were in vitro exposed to C. trachomatis (serovar E or LGV) or C. muridarum, respectively. Then, sperm quality parameters were analyzed. Moreover, male fertility of Chlamydia muridarum infected male C57BL\/6 mice was assessed. Human or murine sperm in vitro exposed to increasing bacterial concentrations or soluble factors from C. trachomatis or C. muridarum, respectively, did not show differences in sperm motility and viability, apoptosis, mitochondrial membrane potential, DNA fragmentation, ROS production and lipid peroxidation levels, when compared with control sperm (p > 0.05). Moreover, no differences in fertility parameters (potency, fecundity, fertility index, pre-and post-implantation loss) were observed between control and infected males. In conclusion, our results indicate that Chlamydia spp. neither directly exerts deleterious effects on spermatozoa nor impairs male fertility.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239056,"idioma_id":4,"titulo":"Male genital tract immune response against Chlamydia trachomatis infection","resumen":"Chlamydia trachomatis is the most commonly reported agent of sexually transmitted bacterial infections worldwide. This pathogenfrequently leads to persistent, long-term, subclinical infections, which in turn may cause severe pathology in susceptible hosts. This isin part due to the strategies that Chlamydia trachomatis uses to survive within epithelial cells and to evade the host immune response,such as subverting intracellular trafficking, interfering signaling pathways and preventing apoptosis. Innate immune receptors such astoll-like receptors expressed on epithelial and immune cells in the genital tract mediate the recognition of chlamydial molecularpatterns. After bacterial recognition, a subset of pro-inflammatory cytokines and chemokines are continuously released by epithelialcells. The innate immune response is followed by the initiation of the adaptive response against Chlamydia trachomatis, which in turnmay result in T helper 1-mediated protection or in T helper 2-mediated immunopathology. Understanding the molecular mechanismsdeveloped by Chlamydia trachomatis to avoid killing and host immune response would be crucial for designing new therapeuticapproaches and developing protective vaccines. In this review, we focus on chlamydial survival strategies and the elicited immuneresponses in male genital tract infections.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239058,"idioma_id":4,"titulo":"Gamma rays from clumpy wind-jet interactions in high-mass microquasars","resumen":"Context. The stellar winds of the massive stars in high-mass microquasars are thought to be inhomogeneous. The interaction of these inhomogeneities, or clumps, with the jets of these objects may be a major factor in gamma-ray production. Aims: Our goal is to characterize a typical scenario of clump-jet interaction, and calculate the contribution of these interactions to the gamma-ray emission from these systems. Methods: We use axisymmetric, relativistic hydrodynamical simulations to model the emitting flow in a typical clump-jet interaction. Using the simulation results we perform a numerical calculation of the high-energy emission from one of these interactions. The radiative calculations are performed for relativistic electrons locally accelerated at the jet shock, and the synchrotron and inverse Compton radiation spectra are computed for different stages of the shocked clump evolution. We also explore different parameter values, such as viewing angle and magnetic field strength. The results derived from one clump-jet interaction are generalized phenomenologically to multiple interactions under different wind models, estimating the clump-jet interaction rates, and the resulting luminosities in the GeV range. Results: If particles are efficiently accelerated in clump-jet interactions, the apparent gamma-ray luminosity through inverse Compton scattering with the stellar photons can be significant even for rather strong magnetic fields and thus efficient synchrotron cooling. Moreover, despite the standing nature or slow motion of the jet shocks for most of the interaction stage, Doppler boosting in the postshock flow is relevant even for mildly relativistic jets. Conclusions: For clump-to-average wind density contrasts greater than or equal to ten, clump-jet interactions could be bright enough to match the observed GeV luminosity in Cyg X-1 and Cyg X-3 when a jet is present in these sources, with required non-thermal-to-total available power fractions greater than 0.01 and 0.1, respectively.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239059,"idioma_id":4,"titulo":"Synthesis of bioadditives of fuels from biodiesel-derived glycerol by esterification with acetic acid on solid catalysts","resumen":"In this paper, glycerol esterification with acetic acid (AA) was studied on several solid acid catalysts: Al2O3, Al-MCM-41, HPA\/SiO2, HBEA, Amberlyst 15 and Amberlyst 36 with the aim of determining the reaction conditions and the nature of the surface acid sites required to produce selectively triacetylglycerol (triacetin). The acidity of the catalysts (nature, density and strength of acid sites) was characterized by temperature-programmed desorption of NH3 and FTIR of adsorbed pyridine. Al2O3 (Lewis acidity) did not show any activity in the reaction. In contrast, highest activity and selectivity to the triacetylated product (triacetin) were obtained on catalysts with Brønsted acidity: Amberlyst 15 and Amberlyst 36. The effect of temperature and molar ratio of AA to glycerol was studied, and the results showed that both parameters have a significant impact on the production of the desired product. Glycerol conversion rate and selectivity to triacetin increased when temperature or AA to glycerol molar ratio were increased, reaching a triacetin yield on Amberlyst 36 of 44% at 393&#8197;K and AA to glycerol molar ratio of 6. Deactivation and reusability of Amberlyst 36 were evaluated by performing consecutive catalytic tests. The presence of some irreversible deactivation due to sulfur loss was observed. In addition, the feasibility of using crude glycerol from biodiesel production as reactant was also investigated. Conversion of crude pretreated glycerol yielded values of triacetin and diacetin similar to those obtained with the commercial pure glycerol although at a lower rate.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239060,"idioma_id":4,"titulo":"Multiple response optimization of heat shock process for separation of bovine serum albumin from plasma","resumen":"Bovine serum albumin produced by heat shock from bovine plasma has been researched on the effects of sodium caprylate concentration [Cap], temperature (T) and pH on yield (Yield%) and purity (BSA%). Response Surface Methodology and Desirability Function approach were applied to optimize its process. The best compromise solution was found: BSA%=95.0 and Yield%=28.5 for a [Cap]=2 mM, T=67.9 °C and pH=5. A Monte Carlo simulation showed that it is possible to obtain excellent values for each individual response. However, a techno-economic feasibility study must be carried out to determine which one is the best option.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239061,"idioma_id":5,"titulo":"Revisitando el nacimiento de la penitenciaría en América Latina veinte años despué","resumen":"El  nacimiento  de  la  penitenciaría  en  América  Latina (1996) presentamos el surgimiento de  la  «prisión  moderna»  latinoameri-cana entre 1830 y 1940. Además de revisitar aquel libro, este  trabajo  pretende  brindar  un  panorama  de  los  trabajos  recientes  sobre el tema. Importantes  libros  han  analizado el  funcionamiento  de  cárceles  en  México,  Chile,  Perú,  Argentina, Brasil, entre otros.  Algunos  han  puesto  de  relieve  el  tema  de  la  vida  en  la  cárcel  desde  la experiencia  de  los  presos  y  los  diversos  aspectos  de  la  representación  de  la  que parten algunos debates sobre el delito  y el  castigo. Por otra parte, a raíz del gran interés por los regímenes autoritarios y las violaciones a los derechos humanos durante los años de la Guerra Fría, hay un creciente número de artículos sobre  las condiciones en las que vivían los presos políticos durante los gobiernos militares de las décadas de 1960  y 1970. Los aportes a  la  historia del encarcelamiento femenino  han sido más escasos,  si  bien  esa  área  de  investigación  despierta  cada  vez  más  interés.  Por  último, en cuanto a  la historia de los reformatorios de menores, más allá de algunas obras importantes, aún queda mucho por indagar.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239062,"idioma_id":4,"titulo":"Doxorubicin: nanotechnological overviews from bench to bedside","resumen":"Doxorubicin (DOX) is considered one of the most effective chemotherapeutic agents, used as a first-line drug in numerous types of cancer. Nevertheless, it exhibits serious adverse effects, such as lethal cardiotoxicity and dose-limiting myelosuppression. In this review, we focus on the description and the clinical benefits of different DOX-loaded nanotechnological platforms, not only those commercially available but also the ones that are currently in clinical phases, such as liposomes, polymeric nanoparticles, polymer?drug conjugates, polymeric micelles and ligand-based DOX-loaded nanoformulations. Although some DOX-based nanoproducts are currently being used in the clinical field, it is clear that further research is necessary to achieve improvements in cancer therapeutics.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239063,"idioma_id":4,"titulo":"A glucose-targeted mixed micellar formulation outperforms Genexol in breast cancer cells","resumen":"Breast cancer represents the top cancer among women, accounting 521.000 deaths per year. Development of targeted nanomedicines to breast cancer tissues represents a milestone to reduce chemotherapy side effects. Taking advantage of the over-expression of glucose (Glu) membrane transporters in breast cancer cells, we aim to expand the potential of a paclitaxel (PTX)-loaded mixed micellar formulation based on polyvinyl caprolactam-polyvinylacetate-polyethylene glycol graft copolymer (Soluplus®) and D-&#945;-tocopheryl polyethylene glycol 1000 succinate (TPGS) by its surface decoration with Glu moieties. The glycopolymer (Soluplus(Glu)) was obtained by microwave-assisted ring opening reaction of &#948;-gluconolactone initiated by Soluplus®. The glycosylation was confirmed by 1H NMR and by agglutination assays employing Concanavalin A. The hydrodynamic diameter of Soluplus(Glu) micelles was characterized by dynamic light scattering (100.3 ± 3.8 nm) as well as the critical micellar concentration value (0.0151%w\/v). Then, a mixed micelle formulation employing Soluplus®, Soluplus(Glu) and TPGS (3:1:1 weight ratio) loaded with PTX (4 mg\/mL) was developed as a multifunctional nanocarrier. Its in vitro anticancer performance in MCF-7 (1.6-fold) and MDA-MB-231 (14.1-fold) was significantly enhanced (p < 0.05) versus the unique commercially available micellar-based PTX-nanoformulation (Genexol®). Furthermore, the in vitro PTX cellular uptake assays revealed that the drug intracellular\/cell content was significantly (p < 0.05) higher for the Glu-containing mixed micelles versus Genexol® after 6 h of incubation with MCF-7 (30.5-fold) and MDA-MB-231 (5-fold). Overall, results confirmed the potential of our Glu-decorated mixed colloidal formulation as an intelligent nanocarrier for PTX-targeted breast cancer chemotherapy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239064,"idioma_id":4,"titulo":"Nanoscale Kolliphor &reg; HS 15 micelles to minimize rifampicin self-aggregation in aqueous media","resumen":"Tuberculosis is a highly-deadly disease that affects both children and adults. Rifampicin, one of the ?first-line? anti tuberculosis drugs, self-aggregates in aqueous solutions where the critical aggregation concentration demonstrated a temperature-dependent behavior. Interestingly, drug self-aggregation could negatively affect the development of liquid aqueous rifampicin pediatric tuberculosis formulations. Therefore, our nanotechnological strategy to minimize this effect was the rifampicin encapsulation within polymeric micelles, employing the commercially available Kolliphor® HS 15, as the micelle-former biomaterial. The results show that Kolliphor® HS 15 is able to prevent rifampicin aqueous self-aggregation and precipitation, when used at certain concentrations. In this context, our work opens the possibility of developing aqueous liquid rifampicin dosage forms for pediatric patients to improve tuberculosis treatment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239065,"idioma_id":5,"titulo":"Escribir la historia del derecho, del delito y del castigo en América Latina","resumen":"Este ensayo  articula  y  pone  de  manifiesto  los  cambios  que  experimentaba,  la  investigación  ligada  a  la historia del delito y el derecho en las últimas dos décadas del siglo XX, y conceptualiza claramente una escuela o campo  de  estudios  agrupable  bajo  la  etiquetade  la  ?historia  social  y  cultural  del  derecho?  en  la  región Latinoamericana. Revela la genealogía intelectual de este campo con sus raíces europeas y norteamericanas, y aísla la especificidad que reviste el estudio de esta materia en América Latina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239068,"idioma_id":4,"titulo":"Growth of Aspergillus flavus and Aspergillus niger aggregate strains isolated from agricultural soils in presence of glyphosate as sole source of carbon, phosphorous or nitrogen","resumen":"Agriculture is one of the bases of the Argentine economy. Glyphosate is undoubtedly one of the most important herbicides used. The increasing consumption and the ef&#64257;ciency of glyphosate-based herbicides have encouraged several studies on their persistence in soils, their effects on soil microbiota and their degradation processes. Fungi have been reported as being the main herbicide-degrading microorganisms as well as the most tolerant to environmentalstress conditions. This study evaluated the growth performance of Aspergillus section Flavi and Aspergillus niger aggregate strains on Czapek Dox media supplied with a commercial glyphosate formulation as sole source of carbon (CZC), phosphorus (CZP) or nitrogen (CZN). Six Aspergillus spp. strains were evaluated. Each medium was stab-inoculated with fungal spores from 7-day old cultures. Two measures of colony radii were taken daily. All of the A. section Flavi strains showed a signi&#64257;cant increase (from 24 to 44%) in growth rate on the CZN medium, as compared to controls. The A. niger aggregate strains exhibited the same behavioral pattern under all the conditions tested, except on the CZN medium. Velutinous or slightly &#64258;occose colonies with abundant sporulation were observed on CZP. Moreover, the colonies produced sparse sporulation on CZC or CZN media, being their appearances completely different from those on the CZP medium. This study establishes that A. section Flavi and A. niger aggregate strains can grow in vitro in the presence of glyphosate, especially when it is used as a sole source of phosphorus or nitrogen.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239070,"idioma_id":5,"titulo":"Primer registro de Pseudapanteles dignus (Hymenoptera: Braconidae) como parasitoide de Tuta absoluta (Lepidoptera: Gelechiidae) en el Alto Valle de Rio Negro, Argentina","resumen":"Se cita por primera vez la presencia del endoparasitoide larval Pseudapanteles dignus (Hymenoptera: Braconidae) atacando a la polilla del tomate Tuta absoluta (Lepidoptera: Gelechiidae) en cultivos de tomate del Alto Valle de Río Negro, siendo este reporte el más austral para la Argentina. Además, se comentan brevemente la diagnosis y el porcentaje de parasitoidismo de P. dignus.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239071,"idioma_id":5,"titulo":"Bioética de las innovaciones genéticas y la inteligencia artificial","resumen":"El presente trabajo tiene como objetivo abordar dos filmes: Never let me go (2010) y Ex-Machina (2015). Se propone para la lectura de los mismos el establecimiento de un contrapunto entre ambos, teniendo como eje la consideración de la dignidad y del estatuto de humanidad al que este concepto viene adherido. En este marco el cine aparece como herramienta para plantearnos dilemas éticos y bioéticos. La aplicación de nuevas tecnologías en seres humanos da lugar a nuevos dilemas en el ámbito biomédico, lo cual plantea dilemas bioéticos. Dentro de dichas tecnologías se encuentran la manipulación genética\/clonación y la generación de inteligencia artificial, temas abordados por las mencionadas películas. Con respecto a estas pueden plantearse distintos interrogantes: ¿Tienen los seres humanos, creados artificialmente para un fin determinado, la misma dignidad que otros? ¿Cómo se argumenta moralmente la intervención de la tecnología para dar lugar a humanos que sean medios para un fin? ¿Cuál es el objetivo de la inteligencia artificial? ¿Puede reemplazar está a los seres humanos? ¿Puede atribuírseles la cualidad de la dignidad? Puede pensarse a estos dilemas éticos, que giran en torno a la humanidad y a la dignidad, interrogadas por las intromisiones de las nuevas tecnologías, como una irrupción de singularidad en un universo donde el hombre era considerado finito y perecedero, ¿y si aparece la posibilidad de la inmortalidad?","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239072,"idioma_id":5,"titulo":"Niveles técnico, deontológico y ético en el uso de tecnologías de la información y la comunicación en psicoterapia","resumen":"La inclusión de tecnologías de la información y comunicación en los tratamientos psicoterapéuticos, genera la necesidad de analizar, por un lado la eficacia de los mismos; y por otro el balance de beneficios e inconvenientes en su implementación. A su vez las diferentes formas de utilizar recursos tecnológicos en el ámbito terapéutico generan la necesidad de pensar los aspectos éticos y deontológicos involucrados. Consentimiento informado, secreto profesional, protección de datos personales, son algunas de las cuestiones principales. Ante la falta de normas deontológicas específicas, los profesionales deben apelar al análisis de principios en que se basan las mismas para dirimir los dilemas que se presentan en torno a la aplicación de las tecnologías de la información y comunicación en psicoterapia, ya que estas constituyen el fundamento del actuar ético de los psicólogos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239074,"idioma_id":5,"titulo":"Las industrias culturales en la convergencia digital. Debates, prácticas y nuevos actores. En Argentina","resumen":"Las transformaciones en el campo de las Industrias Culturales, con la digitalización y la convergencia, constituyen un área relativamente nueva de investigación.  Por ello, se requieren nuevos abordajes teóricos y metodológicos que den cuenta de su cartografía actual.El desarrollo teórico de las IC muestra enfoques variados, provenientes de distintas disciplinas y contextos históricos: comenzando por los pioneros de la Teoría Crítica  y los Estudios Culturales ; la aparición luego de conceptos como Economía de la Información (Castells, 1999) o Culturas Híbridas (García Canclini, 1990), hasta los últimos conceptos de ?crossmedia? o ?transmedia? (Jenkins,2008), ligados a los medios masivos de comunicación. En la actualidad, el mercado digital plantea nuevos desafíos en términos de modelos de negocio y en la reconfiguración y\/o aparición de nuevos actores.El presente trabajo aborda un estado del arte en cuanto al recorrido teórico del campo de las Industrias Culturales y se propone (como un objetivo a largo plazo) investigar los cambios que han experimentado las IC con el advenimiento de la convergencia digital en los últimos diez años en Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239077,"idioma_id":4,"titulo":"Local Field Fluorescence Microscopy: Imaging Cellular Signals in Intact Hearts","resumen":"In the heart, molecular signaling studies are usually performed in isolated myocytes. However, many pathological situations such as ischemiaand arrhythmias can only be fully understood at the whole organ level. Here, we present the spectroscopic technique of local field fluorescencemicroscopy (LFFM) that allows the measurement of cellular signals in the intact heart. The technique is based on a combination of a Langendorffperfused heart and optical fibers to record fluorescent signals. LFFM has various applications in the field of cardiovascular physiology to studythe heart under normal and pathological conditions. Multiple cardiac variables can be monitored using different fluorescent indicators. Theseinclude cytosolic [Ca2+], intra-sarcoplasmic reticulum [Ca2+] and membrane potentials. The exogenous fluorescent probes are excited andthe emitted fluorescence detected with three different arrangements of LFFM epifluorescence techniques presented in this paper. The centraldifferences among these techniques are the type of light source used for excitation and on the way the excitation light is modulated. The pulsedLFFM (PLFFM) uses laser light pulses while continuous wave LFFM (CLFFM) uses continuous laser light for excitation. Finally, light-emittingdiodes (LEDs) were used as a third light source. This non-coherent arrangement is called pulsed LED fluorescence microscopy (PLEDFM).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239080,"idioma_id":5,"titulo":"Arqueología en Rio Mayo,sudoeste del Chubut. Excavación en el Alero Dasovich: resultados preliminares","resumen":"RESUMEN El presente trabajo forma parte de un proyecto de investigaciones arqueológicas en el suroeste del Chubut, que incluyó la excavación del Alero Dásovich, próximo a la localidad de Río Mayo. Su objetivo es dar a conocer los primeros resultados de esta excavación con doce fechados radiocarbónicos y de este modo aportar a la prehistoria del Chubut con imágenes de las ocupaciones del área en distintos momentos. Los fechados más antiguos obtenidos corresponden a 10.000 años AP, datación importante para la prehistoria patagónica. Asimismo, a partir de los resultados preliminares obtenidos, evaluamos las relaciones posibles entre Alero Dásovich y otros sitios arqueológicos próximos en la provincia, así como con zonas colindantes en Chile y el noroeste de Santa Cruz. Palabras claves: Cazadores recolectores; Patagonia central argentina; Poblamiento","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239081,"idioma_id":5,"titulo":"HACIA LA INSTITUCIONALIZACIÓN DEL COMPROMISO SOCIAL UNIVERSITARIO. UN ESTUDIO EN UNIVERSIDADES PÚBLICAS DE LA PROVINCIA DE  SANTA FE","resumen":"Durante los años 2012 a 2015, un grupo interdisciplinario de investigadores de la UNL, UNR y UNLa hemos trabajado en una investigación sobre el Compromiso Social Universitario (CSU). La pregunta que orientó nuestra indagación fue: ¿Cómo entender el CSU y cómo apropiarse de él en el caso concreto de la formación en las carreras vinculadas a las ciencias de la salud, en particular de Bioquímica y Farmacia? Se trabajó con encuestas auto-administradas a docentes universitarios y para tener la perspectiva de los docentes de otros niveles del sistema educativo se realizaron dos grupos de discusión con aquellos docentes que habían participado de actividades de articulación entre la universidad y la escuela en años anteriores. Las reflexiones que continúan son el resultado de dicha indagación, y estuvieron enmarcadas en el proyecto: la formación de profesionales desde la perspectiva del compromiso social universitario. Huellas y olvidos, en el marco de la convocatoria UNL\/CAID orientado 2012.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239085,"idioma_id":4,"titulo":"Alpha Hemoglobinophaties en Rosario, Argentina","resumen":"Hemoglobinopathies are the most commonrecessive diseases worldwide. Whilethe molecular basis of b-thalassemia inRosario has been addressed, that of &#945;-thalassemiaand &#945; structural alterations, hasnot. In this study 105 individuals from differentfamilies referred to our center wereinvestigated for alpha hemoglobinopathiesbecause of low MCV (15%. Six of them witha clinical phenotype of thalassemia intermediawere diagnosed as Hb H disease (fivecases) and Hb H like (one case). It alsoincluded one patient with sickle cell trait,confirmed by hematological and molecularstudies. We were able to identify alpha globingenes mutations in 92 individuals(87.6%): 88 patients with alpha thalassemia,3 patients with structural alterationsand one with both. In total, 13 individuals(12.4%) had no identified &#945;-globinmutation. This study is the first to deal withthe molecular basis of &#945;-hemoglobinophatiesin Rosario","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239086,"idioma_id":4,"titulo":"Screening of pervaporation membranes for the separation of methanolmethyl acetate mixtures: An approach based on the conceptual design of the pervaporation-distillation hybrid process","resumen":"In this work, the pervaporation-distillation hybrid process is proposed to accomplish the separation of the azeotropic mixture methanol-methyl acetate.First, the separation performance of four membranes of a medium-high flux (Pervap 2256, Pervap 2255-30, PolyAl TypM1 and PolyAn) is analyzed with the aid the pervaporation separation index (PSI). For the commercial Pervap 2256 membrane, pervaporation experiments were conducted to characterize its separation performance especially at compositions of the mixture around the azeotrope.Then, a novel screening approach, which is based on the overall cost of the separation corresponding to the optimal Hybrid process design, is proposed. For feed compositions in the range 0.1?0.9 mol\/mol, several process configurations are optimized varying the compositions of the retentate and distillate streams. Quasi-optimal operation temperatures, with correspond to maximum feasible ones, are 348.15 K for the Pervap membranes and 363.15 K for the PolyAn membranes, respectively. The studied membranes are successfully and consistently classified by their respective total cost. The designs corresponding to PolyAl TypM1 and Pervap 2256 membranes present the lowest overall costs.Finally, detailed costs of the vacuum condensing system were also taken into account for the case of the Pervap 2256 membrane to include the permeate pressure as an optimization variable. The optimal value of the permeate pressure is 100 mbar and the corresponding condensation temperature is about 272 K.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239087,"idioma_id":4,"titulo":"Distribution of FMR1 and FMR2 repeats in 2 Argentinean patients with primary ovarian 3 insufficiency","resumen":"The premutation state of FMR1 has been associated with Fragile X-related Premature Ovarian 29 Failure (POI) and is the most common known genetic cause for 46,XX patients. Nevertheless, very 30 few studies analyzed its frequency in Latin American populations. Additionally, a relationship 31 between alleles carrying a cryptic microdeletion in the 5?UTR of FMR2 and the onset of POI has only 32 been studied in one population. 33Our aim was to analyze the incidence of FMR1 premutations and putative microdeletions in 34 exon 1 of FMR2 in a cohort of Argentinean women with POI. We studied 133 patients and 84 35 controls. Fluorescent PCR was performed and the FMR2 exon 1 was further sequenced in samples 36 presenting less than 11 repeats. We found the frequency of FMR1 permutations to be 6.7% and 37 2.9% for familial and sporadic patients, respectively. Among controls , 1\/84 women presented a 38 premutation. In addition, although we did not find microdeletions in FMR2 , we observed a change 39 (T&gt;C) adjacent to the repeats in two sisters with POI. Given the repetitive nature of the sequence 40 involved, we could not ascertain whether this represents a SNP or a deletion. Therefore, a 41 relationship between FMR2 and POI could not be established for our population. 42 43Keywords: primary ovarian insufficiency; FXPOI; FMR1 premutation; FMR2 microdeletions; 44 premature menopause.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239089,"idioma_id":4,"titulo":"The clinical recovery of tuberculosis patients undergoing specific treatment is associated with changes in the immune and neuroendocrine responses","resumen":"Tuberculosis (TB) caused by Mycobacterium tuberculosis is a health problem worldwide. Patients with pulmonary TB show a neuro-immune-endocrine imbalance characterized by an impaired cellular immunity together with increased plasma levels of cortisol, pro- and anti-inflammatory cytokines and markedly decreased dehydroepiandrosterone (DHEA) levels. Extending these findings, we now investigated the immune-endocrine profile of TB patients undergoing specific treatment. Patients (n = 24) were bled at diagnosis (T0), 2, 4, 6 months after treatment initiation and 3 months following its completion. At T0, TB patients showed increased plasma levels of interleukin-6 (IL-6), C reactive protein, interferon-gamma (IFN-&#947;) and transforming growth factor beta (TGF-&#946;). These mediators decreased during treatment, reaching levels similar to those from healthy controls (n = 26). Specific treatment led to an increased lymphoproliferative response along with clinical improvement. Newly diagnosed patients had low levels of DHEA, with increased cortisol amounts and cortisol\/DHEA ratio, which normalized upon specific treatment. As regards glucocorticoid receptors (GR), TB patients at diagnosis presented a reduced mRNA GR&#945;\/GR&#946; ratio in their peripheral blood mononuclear cells. Furthermore, multivariate analysis showed that cortisol\/DHEA ratio was positively associated with inflammatory mediators for which this ratio may constitute a disease biomarker. Anti-mycobacterial treatment results in a better immune-endocrine scenario for the control of physiopathological processes accompanying disease development and hence implied in clinical recovery.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239091,"idioma_id":5,"titulo":"Códigos de Barras: jerarquías, legitimidades y disputas intergeneracionales en una hinchada de fútbol en Argentina","resumen":"El presente artículo aborda la matriz generacional como clave de lectura de la historia de la barra de Los Piratas y como esquema de construcción de fronteras simbólicas entre grupos y facciones de la hinchada. A partir de una metodología etnográfica, este trabajo reconstruye trayectorias y relatos de personajes de tres generaciones diferentes de la barra, las significaciones en torno a la sociabilidad, la violencia como recurso, las lógicas organizativas y los patrones de legitimación en la hinchada. Entendemos que la matriz generacional se manifiesta como una clave metodológica de ingreso al universo moral de estos grupos, y por lo tanto, a los proceso simbólicos a partir de los cuales se construye, legitima y cuestiona el poder en este espacio.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239094,"idioma_id":4,"titulo":"Using niche-modelling and species-specific cost analyses to determine a multispecies corridor in a  fragmented landscape","resumen":"Misiones, Argentina, contains the largest remaining tract of Upper Parana Atlantic Forest ecoregion; however, ~50% of native forest is unprotected and located in a mosaic of plantations, agriculture, and pastures. Existing protected areas are becoming increasingly isolated due to ongoing habitat modification. These factors, combined with lower than expected regional carnivore densities, emphasize the need to understand the effect of fragmentation on animal movement and connectivity between protected areas. Using detection dogs and genetic analyses of scat, we collected data on jaguars (Panthera onca), pumas (Puma concolor), ocelots (Leopardus pardalis), oncillas (Leopardus tigrinus), and bush dogs (Speothos venaticus) across habitats that varied in vegetation, disturbance, human proximity, and protective status. With MaxEnt we evaluated habitat use, habitat suitability, and potential species richness for the five carnivores across northern-central Misiones, Argentina. Through a multifaceted cost analysis that included unique requirements of each carnivore and varying degrees of overlap among them, we determined the optimal location for primary\/secondary corridors that would link the northern-central zones of the Green Corridor in Misiones and identified areas within these corridors needing priority management. A secondary analysis, comparing these multispecies corridors with the jaguar?s unique requirements, demonstrated that this multispecies approach balanced the preferences of all five species and effectively captured areas required by this highly restricted and endangered carnivore. We emphasize the potential importance of expanding beyond a single umbrella or focal species when developing biological corridors that aim to capture the varied ecological requirementsof coexisting species and ecological processes across the landscape. Detection dogs and genetic analyses of scat allow data on multiple species to be collected efficiently across multiple habitat types independent of the degree of legal protection. These data used with multifocal GIS analyses balance the varying degree of overlap and unique properties among them allowing for comprehensive conservation strategies to be developed relatively rapidly. Our comprehensive approach serves as a model to other regions faced with habitat loss and lack of data. The five carnivores focused on in our study have wide ranges, so the results from this study can be expanded and combined with surrounding countries, with analyses at the species or community level.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239102,"idioma_id":4,"titulo":"Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) Activation Balance Astrocyte Polarization into a Proinflammatory Phenotype","resumen":"Astrocytes react to brain injury with a generic response known as reactive gliosis, which involves activation of multiple intracellular pathways including several that may be beneficial for neuronal survival. However, by unknown mechanisms, reactive astrocytes can polarize into a proinflammatory phenotype that induces neurodegeneration. In order to study reactive gliosis and astroglial polarization into a proinflammatory phenotype, we used cortical devascularization-induced brain ischemia in Wistar rats and primary astroglial cell cultures exposed to oxygen-glucose deprivation (OGD). We analyzed the profile of TLR4 expression and the consequences of its activation by gain- and loss-of-function studies, and the effects produced by the activation of triggering receptor expressed on myeloid cells-2 (TREM-2), a negative regulator of TLR4 signaling. Both OGD exposure on primary astroglial cell cultures and cortical devascularization brain ischemia in rats induced TLR4 expression in astrocytes. In vivo, astroglial TLR4 expression was specifically observed in the ischemic penumbra surrounding necrotic core. Functional studies showed that OGD increased the astroglial response to the TLR4 agonist lipopolysaccharide (LPS), and conversely, TLR4 knockout primary astrocytes had impaired nuclear factor kappa-B (NF-&#954;B) activation when exposed to LPS. In gain-of-function studies, plasmid-mediated TLR4 over-expression exacerbated astroglial response to LPS as shown by sustained NF-&#954;B activation and increased expression of proinflammatory cytokines IL-1&#946; and TNF&#945;. TREM-2 expression, although present in naïve primary astrocytes, was induced by OGD, LPS, or high-mobility group box 1 protein (HMGB-1) exposure. TREM-2 activation by antibody cross-linking or the overexpression of TREM-2 intracellular adaptor, DAP12, partially suppressed LPS-induced NF-&#954;B activation in purified astrocytic cultures. In vivo, TREM-2 expression was observed in macrophages and astrocytes located in the ischemic penumbra. While TREM-2+ macrophages were abundant at 3 days post-lesion (DPL) in the ischemic core, TREM-2+ astrocytes persisted in the penumbra until 14DPL. This study demonstrates that TLR4 expression increases astroglial sensitivity to ligands facilitating astrocyte conversion towards a proinflammatory phenotype, and that astroglial TREM-2 modulates this response reducing the downstream NF-&#954;B activation. Therefore, the availability of TLR4 and TREM-2 ligands in the ischemic environment may control proinflammatory astroglial conversion to the neurodegenerative phenotype.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239103,"idioma_id":4,"titulo":"Development of Double Emulsion Nanoparticles for the Encapsulation of Bovine Serum Albumin","resumen":"In the present work, a double emulsion was developed for the encapsulation of BovineSerum Albumin (BSA) as a model protein for the future encapsulation of viral proteins.The first emulsion polydispersity index (PDI) was studied with increasing concentrationsof poly (&#949;-caprolactone) (PCL) as stabilizer (from 16 % w\/v to 5 % w\/v) and polyvinylalcohol (PVA) as the surfactant in the second emulsion at 1.5 % w\/v. Results suggest thatat decreasing concentrations of PCL the PDI of the emulsion also decrease, indicatingthat viscosity of the emulsion is crucial in the homogeneity of the resultant sizedistribution of the nanoparticles. When PVA concentration in the second emulsion wasincreased from 1.5 % w\/v to 2.5 % w\/v the PDI also increased. To study the relationshipbetween the structure of the surfactant in the second emulsion and the resultant BSAencapsulation, emulsions were prepared with Pluronic F68 and PVA both at 1.5 % w\/vand PCL in the first emulsion at 5 % w\/v. Results indicated that Pluronic F68 was a betterstabilizer because at the same experimental conditions encapsulation of BSA was 1.5higher than PVA. FTIR studies confirmed the presence of BSA in the nanoparticles. SEMand TEM microscopies showed a size distribution of 300 nm to 500 nm size ofnanoparticles. Circular dichroism studies demonstrated that the secondary structure of theprotein was conserved after the encapsulation into the nanoparticles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239104,"idioma_id":4,"titulo":"Assessment of Keratinase and Other Hydrolytic Enzymes in Thermophilic Bacteria Isolated from Geothermal Areas in Patagonia Argentina","resumen":"Thermophilic aerobic bacteria were isolated from two geothermal areas in Neuquen province using two different enrichment methods and a total of 30 isolates were obtained. From chicken feather enrichment cultures, strains affiliated to Bacillus cytotoxicus and Bacillus licheniformis were isolated and all of them demonstrated the capability to degrade completely chicken feather. A preliminary research on biotechnological enzymes? potential demonstrated that all the isolates displayed at least one of the extracellular hydrolytic enzymes tested. Most of the isolates showed protease, inulinase and\/or pectinase activities, while cellulase and xylanase activities were less common. In light of these findings, geothermalareas of Argentina may be considered as a potential source of thermophilic bacteria able to produce many industrially relevant enzymes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239106,"idioma_id":5,"titulo":"Desarrollo de un sistema de gestión de tiempos improductivos en tiempo real para una industria maderera dedicada a la producción de molduras finger joint pintadas","resumen":"Se presenta la implementación de sistema de gestión de tiempos improductivos (TI) en tiempo real en una forestoindustria productora y exportadora de molduras de madera de Pinus spp, con un enfoque en reingeniería y gestión industrial. Comprende diagnóstico y evaluación del sistema anterior, se identificaron las falencias y necesidades del nuevo sistema implementado. Se trabajó multidisciplinariamente, se diseñó y se escribió un software, se instalaron equipos electrónicos. Se presenta la versión beta de GesTIOn, totalmente implementado que se adapta a la necesidad gerencial, instalado exitosamente en 13 líneas productivas, registrando los tiempos improductivos a tiempo real y brindando la posibilidad de ser operado remotamente.Durante el desarrollo de la idea del Sistema GesTIOn, surge la posibilidad de desarrollar un  módulo de medición Automática, que se piensa ubicar de manera estratégica en cada línea de producción, que permita medir en la máquina principal el flujo de materiales en el proceso (solamente se detectará el flujo, no su magnitud).El sistema permite la medición automática del inicio del TI, mediante sensor óptico\/encoder. Este sensor envía información a un PLC en cada punto, el cual procesa la información y detectan la interrupción (Imagen 1), y notifica al software, donde se mostrará al oficial de máquina, en pantalla (Imagen 2) y este asigna una causa (Imagen 3). Todo el sistema funciona de acuerdo a exigencias del sistema de gestión de calidad ISO 9001:2008.El procesamiento y análisis de información de TI es la base de GesTIOn, el cual procesa, analiza datos y generar de reportes, en un entorno fácil de utilizar por el personal comprender, seleccionar la información que este desee ver, y le sea útil. (Inclusive a aquellos que tengan un nivel básico de manejo de PC). Por dicho motivo se optó en poner a disposición de los clientes toda la información, desarrollar 3 niveles de análisis de datos: General de planta (Imagen 4); Por línea de producción (Imagen 5); y Sectores de Servicio (Imagen 6). La implementación se ha logrado involucrando a personal de línea, ejecutando permanentes programas de capacitación, evaluación y seguimiento al usuario. El sistema se ha instalado desde hace 16 meses en la empresa, con constantes mejoras y revisiones, y se ha convertido en una herramienta tecnológica eficiente y ágil, que ha brindado un gran aporte hacia la gestión de TI, dando información sobre cuáles son los problemas más urgentes a solucionar para lograr mayor eficiencia y competitividad industrial","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239110,"idioma_id":4,"titulo":"Old and new specimens of a poorly known glyptodont from the Miocene of Patagonia and their biochronological implications","resumen":"The Palaehoplophorini is a tribe of glyptodonts represented by fragmentary specimens for which the oldest recordsoccur in the Pedregoso and Río Mayo formations (middle?late Miocene) in Patagonia (Argentina). The mammal fossilsfrom those formations were the basis for the recognition of the Mayoan fauna, placed between the Friasian sensustricto\/Colloncuran?Laventan and the Chasicoan faunas. The only identified glyptodont from Río Mayo Formation isPalaehoplophorus meridionalis represented only by its type material (i.e., caudal tube) and the precise provenance isunknown. We describe a new specimen of Palaehoplophorus meridionalis collected in the Río Mayo Formation representedby associated osteoderms of the dorsal carapace and postcranial elements, plus part of the type and assignedspecimens that remain unpublished from the old collection. This is the first description of osteoderms from the dorsalcarapace of this species and postcranial elements (the first for a Palaehoplophorini), and the first glyptodont with preciseprovenance from Río Mayo Formation. As result of improving the description and emending the diagnosis, weagree with previous authors about the basal position of Palaehoplophorus meridionalis within the tribe. Finally, wereview the Glyptodontidae association of the Mayoan fauna, which are exclusively represented by Palaehoplophorini(Palaehoplophorus meridionalis and Palaehoplophoroides rothi) and Glyptodontidae indet. This association supports agreater affinity of this fauna with the younger Chasicoan than with the older Friasian sensu stricto\/Colloncuran?Laventanfaunas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239111,"idioma_id":4,"titulo":"High pH in beef longissimus thoracis reduces muscle fibre transverse shrinkage and light scattering which contributes to the dark colour","resumen":"Most studies have focused on myoglobin regarding meat colour development, with little focus on the contribution of muscle structure and light scattering. Our aim was to investigate the pH-dependent changes in muscle structure, on the light scattering properties of the meat. Beef longissimus thoracis muscles were segregated into light, medium or dark colour groups (n&nbsp;=&nbsp;18). ?Dark? muscles had a high ultimate pH (pHu), lower lightness (L*), redness (a*), higher myoglobin concentration and deoxymyoglobin content compared to other muscles. Reflectance confocal laser scanning microscopy (rCLSM) revealed ?dark? muscles had decreased global brightness (indicator of light scattering) and increased fibre width. In a secondary experiment, decreasing the homogenisation buffer pH from 6.10 to 5.40 induced a 17% shrinkage in high pHu muscle fibres, which increased light scattering by ~&nbsp;25%. In conclusion, rCLSM demonstrated that muscle structure contributes to the magnitude of light scattering by a pH dependent mechanism.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239112,"idioma_id":5,"titulo":"Tres paisajes urbanos, una guía histórica","resumen":"El presente trabajo indaga en la comprensión de los paisajes urbanos. Se busca deconstruir su concepción en tres ciudades intermedias argentinas, bonaerenses, mediante la exploración histórico-cultural de una guía turística de mediados del siglo XX.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239113,"idioma_id":4,"titulo":"Chemical and functional characterization of skin, pulp and seed powder from the Argentine native fruit mistol ( Ziziphus mistol ). Effects of phenolic fractions on key enzymes involved in metabolic syndrome and oxidative stress","resumen":"The mistol (Ziziphus mistol) is a native food tree occurring in dry areas of Northwestern and Central Argentina. Studies on its functional properties and bioactive compounds are scarce so far. In this work we assess the nutritional and functional components of lyophilized powder of mistol skin, pulp and seed. The powder from the different fruit parts have moderate carbohydrate content and are an important source of flavonoids, fiber, potassium, magnesium and calcium. The HPLC?ESI-MS\/MS analysis of the polyphenols enriched extracts (PEE) of the samples allowed the identification of 17 compounds including 16 flavonoids and a procyanidin. The PEE showed antioxidant capacity and were able to inhibit &#945;-glucosidase, &#945;-amylase and pancreatic lipase, enzymes related to metabolic syndrome. The results suggest potential of the lyophilized skin, pulp and seed powder from mistol as functional food or dietary supplement in the prevention or treatment of diseases associated with metabolic syndrome.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239116,"idioma_id":5,"titulo":"Cambios, tendencias y desafíos de las políticas científicas recientes en las universidades nacionales de Argentina","resumen":"Este trabajo analiza dos políticas científicas implementadas entre 2004-2015 desde las principales agencias del sector de la Argentina y su incidencia en el marco de las universidades nacionales. Se exploran los alcances de la política de formación de doctores y su influencia en la configuración reciente del posgrado y de la carrera docente en la universidad. Por otra parte, se indaga sobre el influjo de la política de priorización de la investigación científica en las estrategias y orientaciones de los dispositivos universitarios. A través de un abordaje cualitativo, se llevó a cabo un relevamiento documental complementado con entrevistas a autoridades gubernamentales y universitarias.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239119,"idioma_id":4,"titulo":"Tissular Distribution of Argentinean Strains of Bovine Herpesvirus Type 4 (BoHV-4) in Experimentally-Infected Calves","resumen":"Although bovine herpesvirus type 4 (BoHV-4) is primarily associated with reproductive disorders of cattle, it canproduce a variety of clinical signs. To determine the distribution, the presence and type of microscopic lesions causedby BoHV-4 strains of different genotypes an in vivo model, calves were infected with three phylogenetically differentArgentinean BoHV-4 strains. Samples from nasal and ocular secretions, peripheral blood leukocytes, tissues andserum were analyzed. BoHV-4 was isolated from nasal and ocular secretions at 7 and 14 days post-inoculation (dpi).Viral DNA was detected by nested PCR in peripheral blood leukocytes at 14 and 21 dpi for two out of three strainsand in tissues, such as nervous system, trachea, pulmonary and retropharyngeal lymph nodes, spleen and kidney, at21 dpi. Antibody levels detected by viral seroneutralization test were mostly low and varied widely for the differentstrains. The tissue distribution of the BoHV-4 strains and the variations observed in the levels of neutralizing antibodiesindicate that certain differences can be established among the patterns of biological behavior of each strain.This is an initial step to get insight into the biological characteristics of Argentinean BoHV-4 isolates. However,further evaluation involving a higher number of inoculated animals will be required to be conclusive on this aspect.Key words: BoHV-4; Argentinean strains; Tissue Distribution; Cattle*Corresponding","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239120,"idioma_id":5,"titulo":"Construcción de conocimiento rizomático en las Ciencias de la Gestión: implicancias para la comprensión de Organizaciones de Alta Confiabilidad","resumen":"De la arborescencia del mainstream positivista a la actual diversidad paradigmática, las ciencias de la gestión se nutren de múltiples fuentes epistemológicas. El presente trabajo pone en evidencia el carácter rizomático de los estudios organizacionales y sus implicancias para comprender las Organizaciones de Alta Confiabilidad (HROs). En primer lugar, se analizan las fuentes epistemológicas de la disciplina para dar cuenta del pasaje del mainstream positivista hacia la diversidad paradigmática. En la actualidad, la teoría de la organización es un campo disciplinar rizomático, tanto por sus enfoques epistemológicos, la multiplicidad de temas de estudio, la profusión de fuentes disciplinarias como por la diversidad de estrategias metodológicas. Naturaleza epistemológica rizomática que convive con ciertos nudos arborescentes. En segundo lugar, el foco de estudio se traslada hacia las HROs, fenómeno organizacional inherente a las sociedades del riesgo que constituye un desafío epistemológico para las teorías del organizar, tanto para comprender la naturaleza de las HROs como para explicar su performance. Finalmente, se plantea una serie de desafíos epistemológicos a los que se suman las especificidades del universo organizacional argentino, caracterizado por la profusión de organizaciones riesgosas, la recurrencia de accidentes y la incipiente presencia de equipos de investigación que desarrollan el campo disciplinar. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239122,"idioma_id":4,"titulo":"END TIDAL CO2 LEVELS, ADJUSTMENT AND PERFORMANCE IN HIGH-ALTITUDE MOUNTAIN CLIMBING","resumen":"AbstractsDuring the increase of the physical activity the CO2 pressure increases from mild to moderate effort at the end tidal CO2 (PET CO2).Objetive: Our target was to determine the PETCO2 values at rest and after the 6-minute walk test at different heights, as an indicator of severity or mountain climbers? maladaptation to altitudes.Design: This is a retrospective observational study. Methods: The variables of exposition were the measurement of the HR, RF, CO2 and SO2 at rest and in the 6-minute walk test, in three campgrounds.Results: 8 volunteers were included to reach Cerro Plata peak in Argentina (6000 meters). The delta HR index increased to 9 (IC 8-11, p 0.001) beats per minutes as they climbed up. However, when they were compared by groups, the ones who reached the peak had 5 (IC 3-7, p 0.001) beats per minute less than to those who did not make it to the top. The SO2 delta globally increased a 3% in each campground (IC 2-5, p 0.001), still the group which reached the top showed a delta variation of -2% (IC -6 a 1, p 0.21). The delta PETCO2 globally increased a 0.72 in each campground (IC 0.05-1.38, p 0.03), though the group which reached the top showed a delta variation of -3% (IC -4 a -1, p 0.001).Conclusions: A high delta HR would result in the only parameter of bad prognosis in higher campgrounds. Both parameters (SaO2 - PETCO2) showed a lower delta in the 6-minute walk test for those who reached the top.Keywords :Acute mountain sickness; psychological adaptation; lactic acid; end tidal CO2.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239123,"idioma_id":4,"titulo":"Pygoscelis antarcticus feathers as bioindicator of trace element risk in marine environments from Barton Peninsula, 25 de Mayo (King George) Island, Antarctica","resumen":"We report the contents of elements in feathers ofChinstrap penguin (Pygoscelis antarcticus), which had not beeninformed up to now, such as silver and bromine and others listedas hazardous by the United States Environmental ProtectionAgency as arsenic, cobalt, chromium, and mercury. Analysesof the element concentrations in feathers, adult and chicken, fromBarton Peninsulas at 25 de Mayo (King George) Island, SouthShetlands, were made by Instrumental Neutron ActivationAnalysis. Samarium, lanthanum a, thorium, and uranium concentrationsin Chinstrap penguin feathers were below0.1 mg\/kg. This suggests that the elements in feather do notcome from atmospheric particles surface deposition. Arsenic(0.120 ± 0.050 mg\/kg) and cobalt (0.030 ± 0.020 mg\/kg)concentrations were lower than the reports for other colonyof Chinstrap penguins, and essential elements as iron(26 ± 12 mg\/kg), zinc (78.0 ± 5.3 mg\/kg), and chromium(0.51 ± 0.27 mg\/kg) were in the same range while Se(2.90 ± 0.65 mg\/kg) content were the lowest reported.Mercury (0.43 ± 0.21 mg\/kg), chromium (0.210 ± 0.060mg\/kg), and silver (0.083 ± 0.003 mg\/kg) in chicks tendedto be lower than in adults. Iron, cobalt, and arsenic concentrationsin feathers found in this study were the lowest compared tomeasurements were in several penguin species in Antarctica.These results confirm to feathers like effective indicators for thetrace elements incorporated in the penguins and it provide a dataset which can","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239135,"idioma_id":4,"titulo":"Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA","resumen":"Buscar","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239136,"idioma_id":5,"titulo":"ESTRUCTURAS DE PESCA EN EL CANAL BEAGLE","resumen":"En este trabajo se analizan estructuras de rocas emplazadas en el intermareal e interpretadas como corrales de pesca, constituyendo los primeros hallazgos documentados de su tipo para la costa sur de Tierra del Fuego. Si bien entre los casos analizados las características constructivas y los materiales utilizados presentan variabilidad, posiblemente vinculados a situaciones locales, las condiciones de emplazamiento y algunos aspectos morfológicos sugieren un cierto grado de estandarización. Se discute la información obtenida sobre estas estructuras con relación a las descripciones etnográficas y se analizansus implicancias en el contexto de la evidencia arqueológica regional.Las dificultades para su datación absoluta y la escases de evidencia contextual asociada a estas estructuras limita sensiblemente las posibilidades interpretativas acerca del rol que esta tecnología habría tenido a lo largo de la secuencia arqueología del canal Beagle. No obstante, el progresivo elevamiento de las costas por efecto de la glacioeustacia y del ascenso tectónico, conjuntamente con la localización de estas estructuras en el intermareal sugiere que los casos aquí presentados corresponderían a momentos finales del Holoceno. Por tanto, se plantea una potencial vinculación con el proceso de intensificación propuesto para momentos tardíos en el área.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239137,"idioma_id":5,"titulo":"PRIMEROS DATOS SOBRE EL USO DE RECURSOS LEÑOSOS DURANTE EL HOLOCENO TEMPRANO EN EL CANAL BEAGLE: ESTUDIO ARQUEOBOTÁNICO DEL SITIO IMIWAIA I (TIERRA DEL FUEGO, ARGENTINA)","resumen":"Este trabajo tiene por objetivo estudiar el uso de los recursos vegetales leñosos llevado a cabo por sociedades cazadoras-recolectoras que habitaron el sitio Imiwaia I (costa norte del canal Beagle) durante el Holoceno temprano. Los resultados alcanzados indican que las sociedades cazadoras recolectoras del sur de Tierra del Fuego hicieron un uso heterogéneo y local del material leñoso utilizado como combustible. Se utilizaron especies arbóreas y arbustivas, siendo Nothofagus pumilio y Berberis sp. los taxones con mayor representación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239138,"idioma_id":4,"titulo":"NATURAL ACCUMULATION AND DISTRIBUTION OF GUANACO BONES IN THE SOUTHERNMOST TIP OF TIERRA DEL FUEGO (ARGENTINA): TAPHONOMIC ANALYSIS AND ARCHAEOLOGICAL IMPLICATIONS","resumen":"In this study we evaluate modern accumulation, dispersion and preservation patterns of guanaco bones(Lama guanicoe) and discuss their implications for the zooarchaeological record of coastal Tierra delFuego in southern South America. We surveyed four environmental units: the supra-tidal zone, forests,grasslands, and peat bogs. The guanaco assemblages consist of both disarticulated and articulated bones,most represented by limbs and heads (only two nearly complete carcasses were recorded). Naturalprocesses such as marine abrasion largely affected the preservation of specimens, while weathering is aconspicuous effect observed on bones from the forest. Age and sex profiles, as well as variability inpreservation, reflect attritional deaths in different time periods. The guanaco seems to be found regularly alongthe southeast coasts, being an available resource for coastal and marine hunter-gatherers with relativelynarrow foraging ranges. The presence of guanaco is higher during autumn and winter. Bone remains aresubject to vertical migration in peat bogs, grasslands and other soft substrates, allowing time-averagingof faunal assemblage formations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239139,"idioma_id":4,"titulo":"SPATIAL PATTERNING AND OCCUPATION DYNAMICS DURING THE EARLY HOLOCENE IN AN ARCHAEOLOGICAL SITE FROM THE SOUTH COAST OF TIERRA DEL FUEGO: BINUSHMUKA I","resumen":"We explore the implications of the spatial structure of the artifact assemblages at the Binushmuka I site, located in the north coast of the Beagle Channel (Tierra del Fuego). The information corresponding to the stratigraphy, chronology and composition of the archaeological assemblages of this site is described. We focus on the spatial distribution of artifacts, which mainly depend on the number and duration of the occupations and the size of the group, to evaluate the temporal structure of the assemblages. For assessing pattern mobility, we also consider the spatial consistency of the location of the site in relation to features of the paleogeography and the archaeological landscape.The confined size of the assemblages (~7m2) and the low degree of size sorting observed in the earlier record of Binushmuka are likely to represent short-term occupations by small sized groups. The spatial consistency between early Holocene occupations and marine hunter-gatherer assemblages observed at a regional level suggests that groups with similar mobility and foraging strategies could have occupied the site.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239141,"idioma_id":4,"titulo":"Interacting opinion and disease dynamics in multiplex networks: Discontinuous phase transition and nonmonotonic consensus times","resumen":"Opinion formation and disease spreading are among the most studied dynamical processes on complex networks. In real societies, it is expected that these two processes depend on and affect each other. However, little is known about the effects of opinion dynamics over disease dynamics and vice versa, since most studies treat them separately. In this work we study the dynamics of the voter model for opinion formation intertwined with that of the contact process for disease spreading, in a population of agents that interact via two types of connections, social and contact. These two interacting dynamics take place on two layers of networks, coupled through a fraction q of links present in both networks. The probability that an agent updates its state depends on both the opinion and disease states of the interacting partner. We find that the opinion dynamics has striking consequences on the statistical properties of disease spreading. The most important is that the smooth (continuous) transition from a healthy to an endemic phase observed in the contact process, as the infection probability increases beyond a threshold, becomes abrupt (discontinuous) in the two-layer system. Therefore, disregarding the effects of social dynamics on epidemics propagation may lead to a misestimation of the real magnitude of the spreading. Also, an endemic-healthy discontinuous transition is found when the coupling q overcomes a threshold value. Furthermore, we show that the disease dynamics delays the opinion consensus, leading to a consensus time that varies nonmonotonically with q in a large range of the model´s parameters. A mean-field approach reveals that the coupled dynamics of opinions and disease can be approximately described by the dynamics of the voter model decoupled from that of the contact process, with effective probabilities of opinion and disease transmission.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239142,"idioma_id":4,"titulo":"Nonalcoholic fatty liver disease associated with metabolic syndrome. Influence of liver fibrosis stages on characteristics of very low density lipoproteins.","resumen":"Background: We evaluated possible changes in VLDLcharacteristics, and metabolic related factors, in MetS-associatedNAFLD and accompanying liver fibrosis.Methods: We studied 36 MetS patients with biopsy-proven NAFLD (MetS +NAFLD) and 24 MetS without ultrasoundNAFLD evidence. Further, MetS+NAFLD was sub-divided according to fibrosis stage into, non-tomoderate(F0?F2, n =27) and severe (F3?F4, n= 9) fibrosis. We measured: lipid profile, VLDL composition andsize (size exclusion-HPLC), CETP and lipoprotein lipase (LPL) activities and adiponectin. Additionally, in MetS+ NAFLD type IV collagen 7S domain was measured.Results: MetS+NAFLD showed increased VLDL-mass, VLDL particle number, VLDL-triglyceride% and largeVLDL-% (p < 0.04). CETP activity tended to increase in MetS +NAFLD (p = 0.058), while LPL activity wasunchanged. Moreover, in MetS +NAFLD, adiponectin was decreased (p < 0.001), and negatively correlatedwith VLDL-mass and VLDL particle number (p < 0.05), independently of insulin-resistance. Within MetS+ NAFLD group, despite greater insulin-resistance, patients with severe fibrosis showed lower plasma triglycerides,VLDL-mass, VLDL-triglyceride%, large VLDL-% and CETP activity (p < 0.05), while type IV collagenwas increased (p =0.009) and inversely correlated with large VLDL-% (p =0.045).Conclusions: In MetS, NAFLD is associated with larger and triglyceride over-enriched circulating VLDLs, ofgreater atherogenicity. However, when NAFLD progresses to severe fibrosis, circulating VLDL features apparentlyimproved, probably due to early alterations in hepatic synthetic function.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239181,"idioma_id":4,"titulo":"Barriers and facilitators to the implementation of antenatal syphilis screening and treatment for the prevention of congenital syphilis in the Democratic Republic of Congo and Zambia: results of qualitative formative research.","resumen":"BACKGROUND:The impact of untreated syphilis during pregnancy on neonatal health remains a major public health threat worldwide. Given the high prevalence of syphilis during pregnancy in Zambia and Democratic Republic of Congo (DRC), the Preventive Congenital Syphilis Trial (PCS Trial), a cluster randomized trial, was proposed to increase same-day screening and treatment of syphilis during antenatal care visits. To design an accepted and feasible intervention, we conducted a qualitative  formative research. Our objective was to identify context-specific  barriers and facilitators to the implementation of antenatal screening and treatment during pregnancy.METHODS:Qualitative research included in-depth semi-structured interviews with clinic administrators, group interviews with health care providers, and focus groups with pregnant women in primary care clinics (PCCs) in Kinshasa (DRC) and Lusaka (Zambia).RESULTS:A total of 112 individuals participated in the interviews and focus groups. Barriers for the implementation of syphilis testing and treatment were identified at the a) system level: fragmentation of the health system, existence of ANC guidelines in conflict with proposed intervention, poor accessibility of clinics (geographical and functional), staff and product shortages at the PCCs; b) healthcare providers´ level: lack of knowledge and training about evolving best practices, reservations regarding same-day screening and treatment; c) Pregnant women level: late enrollment in ANC, lack of knowledge about consequences and treatment of syphilis, and stigma. Based on these results, we developed recommendations for the design of the PCS Trial intervention.CONCLUSION:This research allowed us to identify barriers and facilitators to improve the feasibility and acceptability of a behavioral intervention. Formative research is a critical step in designing appropriate and effective interventions by closing the 'know-do gap'.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239182,"idioma_id":4,"titulo":"Sources of influence on pregnant women's preferred mode of delivery in Buenos Aires, Argentina.","resumen":"BACKGROUND:Understanding influences on women´s preferred delivery mode is vital for planning interventions to reduce cesarean rates and for ensuring that women receive correct information. Our objectives were to: determine if sources of information influencing a pregnant woman´s preferred delivery mode and knowledge of cesarean indications differ by sociodemographic characteristics; to conduct a factor analysis of items related to information sources influencing this preference; and to determine if knowledge differs by information sources influencing this preference or their underlying latent constructs.METHODS:Data from a prospective cohort study conducted in Buenos Aires was analyzed. Healthy nulliparous women aged 18-35, at >32 weeks of gestation and with live, singleton pregnancies participated. The primary research questions were evaluated using Chi-square tests, factor analysis, logistic regression, and generalized estimating equations.RESULTS:A total of 382 women participated in the study. Women of lower socioeconomic status were more influenced by people, magazines and TV\/movies in their mode of delivery preferences, and had poorer knowledge of cesarean indications. Sources of influence for preferred delivery mode and factors derived in factor analysis were not associated with knowledge level when considered individually or together, or when adjusted for sociodemographic characteristics, or when accounting for clustering by the hospital sector (public or private).CONCLUSIONS:Higher socioeconomic status is associated with being less influenced by people and with better knowledge of indications for cesarean delivery. Knowledge of cesarean indications was not associated with the source of information about mode of delivery preferences.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239183,"idioma_id":4,"titulo":"The PRECIS-2 tool has good interrater reliability and modest discriminant validity.","resumen":"AbstractOBJECTIVES:PRagmatic Explanatory Continuum Indicator Summary (PRECIS)-2 is a tool that could improve design insight for trialists. Our aim was to validate the PRECIS-2 tool, unlike its predecessor, testing the discriminant validity and interrater reliability.STUDY DESIGN AND SETTING:Over 80 international trialists, methodologists, clinicians, and policymakers created PRECIS-2 helping to ensure face validity and content validity. The interrater reliability of PRECIS-2 was measured using 19 experienced trialists who used PRECIS-2 to score a diverse sample of 15 randomized controlled trial protocols. Discriminant validity was tested with two raters to independently determine if the trial protocols were more pragmatic or more explanatory, with scores from the 19 raters for the 15 trials as predictors of pragmatism.RESULTS:Interrater reliability was generally good, with seven of nine domains having an intraclass correlation coefficient over 0.65. Flexibility (adherence) and recruitment had wide confidence intervals, but raters found these difficult to rate and wanted more information. Each of the nine PRECIS-2 domains could be used to differentiate between trials taking more pragmatic or more explanatory approaches with better than chance discrimination for all domains.CONCLUSION:We have assessed the validity and reliability of PRECIS-2. An elaboration study and web site provide guidance to help future users of the tool which is continuing to be tested by trial teams, systematic reviewers, and funders.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239185,"idioma_id":5,"titulo":"SALUD PÚBLICA Y ORGANISMOS INTERNACIONALES EN LA TRAYECTORIA ACADÉMICO-PROFESIONAL DEL DOCTOR DAVID SEVLEVER","resumen":"El presente artículo indaga el rol cumplido por organismos internacionales como la Fundación Rockefeller (FR) y la Organización Panamericana de la Salud (OPS) en el recorrido profesional del sanitarista argentino David Sevlever, quien se valió de contactos internacionales y estancias formativas en el exterior para construir una carrera en el naciente campo de la Salud Pública en Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239197,"idioma_id":4,"titulo":"Magnetic memory effect in magnetite charged polypropylene composite*","resumen":"The behaviour of damping and dynamic shear modulus in polypropylene charged with either different volume fraction or size of magnetite (Fe3O4) particles, as a function of the applied magnetic field at 318, 353 and 403&nbsp;K; has been studied. An increase of the alternating magnetic field oscillating with 50&nbsp;Hz, leads to an increase of the damping. In addition, during the subsequently decreasing alternating magnetic field, the damping decreases, but a hysteretic behaviour appeared. The behaviour of the damping and the elastic modulus under the application of an alternating magnetic field was explained by the development of a magnetic fatigue damage occurring around the particle interface due to oscillation of magnetite particles. In contrast, during the increase of a direct magnetic field, the damping decreases and the elastic modulus increases. Measurements performed at 353 and 403&nbsp;K allowed observing the interaction process among the particles of magnetite in the polymer matrix. After the decrease in the direct magnetic field, from the maximum reached value, damping and modulus remain smaller and higher, respectively; giving rise to a memory effect. In addition, a mesoscopic description of magnetite filled polymer composite materials has been performed in the continuous media by considering the interaction between magnetic and mechanical forces. Theoretical predictions of here developed model were qualitatively applied with good success for explaining the memory effect in magnetite filled polypropylene under the application of a direct magnetic field.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239198,"idioma_id":4,"titulo":"Influence of thermal treatments on the mechanical properties and the martensitic transformation in Fe-Pd-Mn ferromagnetic shape memory alloy","resumen":"The effects of high temperature thermal treatments on the hardening behaviour, the damping capacity and the martensitic transformation in Fe66.8Pd30.7Mn2.5 Ferromagnetic Shape Memory Alloy have been determined by mechanical spectroscopy. Annealing below 753 K, lead to a hardening of the alloy without a marked decrease in the damping capacity. In addition, they increase both the austenite finish transformation temperature and the intensity of the damping peak related to the martensitic transformation. This variation can be controlled by the small volume fraction precipitation of small &alpha; phase particles. In contrast, thermal treatments performed above 753 K lead to a further hardening of the alloy, but they decrease the austenitic finish transformation temperature and the intensity of the damping peak related to the martensitic transformation; as a consequence of the decomposition of the metastable &gamma; phase into the &alpha;+&gamma;1 stable phases. In addition, two new damping peaks related to the mobility of dislocations and grain boundaries have been discovered at around 700 K and 900 K, respectively.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239199,"idioma_id":4,"titulo":"Study of the martensitic transition in Ni-Mn-Sn-Ti ferromagnetic shape memory alloys","resumen":"In the present work, mechanicalspectroscopy measurements as a function of temperature and strain have been performed in (at.%) Ni50Mn37Sn13-xTix(x=0, 0.5 and 2) ferromagnetic shape memory alloys in order both to studymartensitic transition phenomenon and also to determineits temperature of appearance. For mechanical spectroscopy measurements, a fiveelements piezoelectric device recently developed has been used. Inaddition, other characterization techniques as, differential thermal analysisand superconducting quantum interference magnetic spectroscopy, werealso used. Besides, relaxation processes near the martensitic transitiontemperature have been also observed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239200,"idioma_id":4,"titulo":"Denaturation processes of collagen from cow bones as a function of temperature","resumen":"Thethermal stability of type I collagen from cow bones, either femur and ribs, wasstudied in the temperature range from 250 K up to 670 K by means of dynamicmechanical analysis, scanning electron microscopy and infrared absorptionspectroscopy. Several stages of denaturation were found in the temperaturerange from 320 K up to 670 K. The experimental results reveal the denaturationprocesses which take place at the collagen including also the triple helixtowards the random coil transition of the collagen fibrils.Thedifferences between the denaturation processes in the femur and ribs arehighlighted and the physical-chemical mechanisms controlling the denaturationprocesses are discussed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239201,"idioma_id":4,"titulo":"Influence of defects on the irreversible phase transition in the Fe-Pd doped with Co and Mn","resumen":"The appearance of BCT martensite in Fe-Pd-basedferromagnetic shape memory alloys, which develops at lower temperatures thanthe thermoelastic martensitic transition, deteriorates the shape memoryproperties. In a previous work performed in Fe70Pd30, itwas shown that a reduction in defects density due to the structure recovery bythermal treatment above 673 K clearly stabilizes the alloy, reducing the nonthermoelastic FCT-BCT transformation temperature, and increasing thetemperature range where the thermoelastic FCT can occur. In the present work,the influence of quenched-in-defects upon the intensity and temperature of thethermoelastic martensitic (FCC-FCT) and the non thermoelastic (FCT-BCT)transitions in Fe67Pd30Co3 and Fe66.8Pd30.7Mn2.5ferromagnetic shape memory alloys; is studied. Infact, dislocation dynamics has been studied by means of mechanical spectroscopy,while the martensitic transition temperatures have been determined through differentialscanning calorimetry. A good correlation between the behaviour of thenon-thermoelastic transition has been observed from mechanical spectroscopy anddifferential scanning calorimetry studies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239202,"idioma_id":4,"titulo":"Study of dielectric strength in EPDM by nondestructive dynamic mechanical analysis in high electrical field","resumen":"In thepresent work the value of the degree of the area swept by the polymer chain dueto an electrical force for a given mesostructure was related to thecorresponding value of the dielectric strength. This value was deduced from theelectric inclusion formalism applied to dynamic mechanical analysis (DMA)studies conducted under high electric field, which were performed in commercialethylene-propylene-diene M-class rubber (EPDM); used for the housing ofpolymeric electrical insulators. EPDM samples with different arrangements ofthe polymer chains and crystalline degree, promoted by controlled neutronirradiation were studied. Several characterization techniques, as infraredabsorption spectroscopy (IR), differential scanning calorimetry (DSC), positronannihilation lifetime spectroscopy (PALS) and dielectric strength (DS) werealso used. The relationship between the DS and the degree of movement ofpolymer chains promoted by electrical forces coming from the electric fieldapplied in a non destructive test as the DMA was successfully established. Infact, a larger empty space in the sample leads to larger areas swept by thepolymer chains during bending under the application of the field strength inthe dynamic mechanical analysis tests. Therefore, an increase in the capabilityof movement of charges occurs, corresponding to smaller dielectric strengthvalues. Crystallinity improves the dielectric strength due to the increase inthe internal stresses which decreases the capability of movement of the polymerchains and electric carriers by electric forces","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239204,"idioma_id":5,"titulo":"Presentación Oteaiken Boletín N° 23 'Luchas por el reconocimiento y discapacidad'","resumen":"En este texto se introduce al Dossier Luchar por el reconocimiento y discapacidad.El artículo se compone de dos partes. En la primera parte se introduce al tema. Se caracteriza la situación de estigmatización y exclusión históricamente experimentada por esta minoría, así como los cuestionamientos a estas formas de opresión entabladas por el colectivo de personas con discapacidad desde los años 70 en el mundo anglosajón. Se da cuenta suscintamente de los efectos de dichas luchas por el reconocimiento en el plano de los derechos humanos y en los estudios sociales sobre la discapacidad. Destacando como punto de llegada de estas tendencias a la Convención Internacional sobre los Derechos de las Personas con Discapacidad, firmada ante la Asamblea General de la ONU en 2006 y con amplia ratificación a nivel mundial, se plantean los desafíos que presenta la misma para garantizar la inclusión de este sector de la población y para analizar estos procesos desde las Ciencias Sociales. En la segunda parte, presentamos los diez artículos que componen el Dossier, los cuales conjugaron aportes de Colombia, Uruguay, Argentina, Chile, México, Canadá, España, Francia y Canadá. Sus miradas, transnacionales e interdisciplinarias, conjugan formas y contenidos que nutren a la discapacidad como temática a deconstruir desde el modelo social.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239205,"idioma_id":5,"titulo":"Belleza, vida activa y vida contemplativa.","resumen":"Cuando se aborda el estudio del pulchrum en Tomás de Aquino desde una perspectiva integral, es posible apreciar que este communissima transita todos los niveles de lo creado, desde el mundo físico, pasando por el cuerpo humano como microcosmos, hasta aquellas actividades humanas más esenciales que la tradición ha asociado a la vida activa y a la contemplativa. En tal sentido, lo bello de la creación inicia la contemplación e invita a embellecer la interioridad humana mediante un perfeccionamiento que, trascendiendo el esfuerzo particular,&nbsp; confía a la gracia la propia plenitud. El presente trabajo, entonces, quiere mostrar desde la mirada tomasina esta via pulchri, centrándose particularmente en las virtudes que corresponden a estas dos vidas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239206,"idioma_id":4,"titulo":"Tissular Distribution of Argentinean Strains of Bovine Herpesvirus Type 4 (BoHV-4) in Experimentally-Infected Calves","resumen":"Although bovine herpesvirus type 4 (BoHV-4) is primarily associated with reproductive disorders of cattle, it canproduce a variety of clinical signs. To determine the distribution, the presence and type of microscopic lesions causedby BoHV-4 strains of different genotypes an in vivo model, calves were infected with three phylogenetically differentArgentinean BoHV-4 strains. Samples from nasal and ocular secretions, peripheral blood leukocytes, tissues andserum were analyzed. BoHV-4 was isolated from nasal and ocular secretions at 7 and 14 days post-inoculation (dpi).Viral DNA was detected by nested PCR in peripheral blood leukocytes at 14 and 21 dpi for two out of three strainsand in tissues, such as nervous system, trachea, pulmonary and retropharyngeal lymph nodes, spleen and kidney, at21 dpi. Antibody levels detected by viral seroneutralization test were mostly low and varied widely for the differentstrains. The tissue distribution of the BoHV-4 strains and the variations observed in the levels of neutralizing antibodiesindicate that certain differences can be established among the patterns of biological behavior of each strain.This is an initial step to get insight into the biological characteristics of Argentinean BoHV-4 isolates. However,further evaluation involving a higher number of inoculated animals will be required to be conclusive on this aspect.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239207,"idioma_id":4,"titulo":"The stringent response plays a key role in Bacillus subtilis survival of fatty acid starvation","resumen":"The stringent response is a universal adaptive mechanism to protect bacteria from nutritional and environmental stresses. The role of the stringent response during lipid starvation has been studied only in Gram-negative bacteria. Here, we report that the stringent response also plays a crucial role in the adaptation of the model Gram-positive Bacillus subtilis to fatty acid starvation. B. subtilis lacking all three (p)ppGpp-synthetases (RelBs, RelP and RelQ) or bearing a RelBs variant that no longer synthesizes (p)ppGpp suffer extreme loss of viability on lipid starvation. Loss of viability is paralleled by perturbation of membrane integrity and function, with collapse of membrane potential as the likely cause of death. Although no increment of (p)ppGpp could be detected in lipid starved B. subtilis, we observed a substantial increase in the GTP\/ATP ratio of strains incapable of synthesizing (p)ppGpp. Artificially lowering GTP with decoyinine rescued viability of such strains, confirming observations that low intracellular GTP is important for survival of nutritional stresses. Altogether, our results show that activation of the stringent response by lipid starvation is a broadly conserved response of bacteria and that a key role of (p)ppGpp is to couple biosynthetic processes that become detrimental if uncoordinated.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239208,"idioma_id":4,"titulo":"Signal Sensing and Transduction by Histidine Kinases as Unveiled through Studies on a Temperature Sensor","resumen":"ConspectusHistidine kinases (HK) are the sensory proteins of two-component systems, responsible for a large fraction of bacterial responses to stimuli and environmental changes. Prototypical HKs are membrane-bound proteins that phosphorylate cognate response regulator proteins in the cytoplasm upon signal detection in the membrane or periplasm. HKs stand as potential drug targets but also constitute fascinating systems for studying proteins at work, specifically regarding the chemistry and mechanics of signal detection, transduction through the membrane, and regulation of catalytic outputs.In this Account, we focus on Bacillus subtilis DesK, a membrane-bound HK part of a two-component system that maintains appropriate membrane fluidity at low growth temperatures. Unlike most HKs, DesK has no extracytoplasmic signal-sensing domains; instead, sensing is carried out by 10 transmembrane helices (coming from two protomers) arranged in an unknown structure. The fifth transmembrane helix from each protomer connects, without any of the intermediate domains found in other HKs, into the dimerization and histidine phosphotransfer (DHp) domain located in the cytoplasm, which is followed by the ATP-binding domains (ABD). Throughout the years, genetic, biochemical, structural, and computational studies on wild-type, mutant, and truncated versions of DesK allowed us to dissect several aspects of DesK´s functioning, pushing forward a more general understanding of its own structure\/function relationships as well as those of other HKs. We have shown that the sensing mechanism is rooted in temperature-dependent membrane properties, most likely a combination of thickness, fluidity, and water permeability, and we have proposed possible mechanisms by which DesK senses these properties and transduces the signals. X-ray structures and computational models have revealed structural features of TM and cytoplasmic regions in DesK´s kinase- and phosphatase-competent states. Biochemical and genetic experiments and molecular simulations further showed that reversible formation of a two-helix coiled coil in the fifth TM segment and the N-terminus of the cytoplasmic domain is essential for the sensing and signal transduction mechanisms.Together with other structural and functional works, the emerging picture suggests that diverse HKs possess distinct sensing and transduction mechanisms but share as rather general features (i) a symmetric phosphatase state and an asymmetric kinase state and (ii) similar functional outputs on the conserved DHp and ABD domains, achieved through different mechanisms that depend on the nature of the initial signal. We here advance (iii) an important role for TM prolines in transducing the initial signals to the cytoplasmic coiled coils, based on simulations of DesK´s TM helices and our previous work on a related HK, PhoQ. Lastly, evidence for DesK, PhoQ, BvgS, and DctB HKs shows that (iv) overall catalytic output is tuned by a delicate balance between hydration potentials, coiled coil stability, and exposure of hydrophobic surface patches at their cytoplasmic coiled coils and at the N-terminal and C-terminal sides of their TM helices. This balance is so delicate that small perturbations, either physiological signals or induced by mutations, lead to large remodeling of the underlying conformational landscape achieving clear-cut changes in catalytic output, mirroring the required response speed of these systems for proper biological function.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239209,"idioma_id":5,"titulo":"Territorio, elites y redes socio-institucionales en la Provincia de Córdoba, Argentina, hacia el siglo XX. Modelos en disputa, industrialismo vs agronegocios.","resumen":"El análisis de la emergencia yconsolidación de redes de distinta naturaleza y alcance asigna una importanciacreciente dentro de los estudios territoriales. Diferentes autores consideranal territorio como un conjunto de relaciones políticas, económicas, sociales,culturales y ecológicas que se caracterizan como una red construida sobre unahistoria territorial.En este artículo se hace hincapié en la estructura espacial y económica en laregión sur de la provincia de Córdoba, Argentina, con foco en la ciudad de RíoCuarto, identificando las redes socio-institucionales construidas por lasélites dominantes y sus principales vínculos a través del tiempo. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239210,"idioma_id":4,"titulo":"Nematode Infection on Beef Cattle in Two Different Productive Regions of Argentina?s Northwest","resumen":"Cattle production in northwest Argentina (NOA) in the last 10 years has grown in importance. However, this growth of livestock brought productive and health constraints such as infection with gastrointestinal nematodes (GIN). Nematode infection may reduce productivity of grazing cattle [1-5]. Free-living forms of GIN exhibit a close relationship with climatic factors, the environment and animal management, affecting GIN development, survival and final infestation rate of pastures [1-7]. Thus, there are marked differences in epidemiology and effect of GINs among regions and production systems. The NOA region is characterized by a subtropical climate with a dry winter season and summer rainfalls, and the presence of different agroecological regions. These areas have been largely modified by human activities and are used for cattle raising such as Chaco Semiarid forests (CSF) and piedmont forests and grasslands (PFG).Knowledge about the GIN of beef cattle in the NOA is scarce [4], particularly for CSF and PFG regions. Therefore, the aim of this work was to study the epidemiology of GINs and their effects on replacement beef heifers in representative productive systems of CSF and PFG regions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239211,"idioma_id":5,"titulo":"Intoxicación experimental con Nierembergia linariifolia var. linariifolia en cabras","resumen":"Nierembergia linariifolia var. linariifolia ha sido sospechada históricamente como planta tóxica en algunas regiones del noroeste de Argentina. Se administró una dosis de 10 g de materia seca de planta molida\/kg de peso, a tres cabras adultas mediante el empleo de sonda nasogástrica. Otros tres animales permanecieron como grupo control y recibieron heno de alfalfa. Las cabras que recibieron la planta, presentaron signos clínicos de cólico abdominal entre las 7 y 45 horas post-administración. Ninguno de los animales murió y todos se recuperaron totalmente a las 72 horas de iniciado el ensayo. Nierembergia linariifolia var. linariaefolia demostró tener efectos tóxicos a nivel gastrointestinal a la dosis administrada, aunque no se observaron daños más severos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239214,"idioma_id":5,"titulo":"'El arreglo queer en la lectura de poesía'","resumen":"Resumen: El presente trabajo toma como punto de partida la premisa de Peter Szendy de que el arreglo musical inscribe una escucha al igual que la traducción.  A partir de esta idea, pensamos un próximo nivel de análisis que corresponde a la escucha de una traducción, registrada en la lectura en voz alta. Para esto, tomamos un poema de Marosa di Giorgio, su traducción al inglés, y luego de pensar la escucha de la traductora, exploraremos la escucha que hace la poeta Joyelle McSweeney cuando lee el poema en inglés en voz alta y nuestra escucha de ese arreglo. Así, comprobamos que la traducción abre otro ?horizonte de arreglo? que revela nuevas posibilidades de análisis de la voz, y una transformación de la voz primera del texto fuente en un espiral inagotable que transita lenguajes, medios y tradiciones literarias. Dicho análisis refuerza la importancia de una atención mayor a la plasticidad de la escucha de la voz y nos revela que la escucha, al igual que toda manifestación del arte, es más que doble y bífida (Szendy), es inherentemente plural y queer.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239215,"idioma_id":5,"titulo":"Traducir textos indóciles","resumen":"RESUMEN: En este trabajo propongo presentar el relato ?The Warm Mouth? de Joyelle McSweeney (1976-) para comentar mi traducción al español, una vez consideradas las nociones conocidas de esta autora con respecto a la traducción, el cuerpo abyecto, el género (en ambos sentidos del término) y lo sublime. El relato, que forma parte del libro Salamandrine: 8 Gothics (2013), constituye una reescritura de la historia de los músicos de Bremen, y refleja, claramente, la supervivencia en medio de la opresión capitalista, contaminante y letal. Tomando como punto de partida la premisa de Burke acerca de lo sublime: ?una calculada oscuridad en algunas cosas contribuye al efecto del cuadro [?] porque lo oscuro, confuso, incierto en las imágenes tiene un poder mayor sobre la fantasía para generar las mayores pasiones que lo que es más claro y determinado? (1996, p.136), observamos que en el relato de McSweeney, lo abyecto y lo oscuro, a veces difuso o indefinible, tienen un papel protagónico, pues se busca romper con los límites establecidos y llamar la atención sobre las definiciones de los cuerpos. La traducción que realizo de este relato, entonces, intenta replicar y justificar los modos en que el texto se muestra oscuro, abyecto e indócil con el fin de visibilizar las barreras de convenciones literarias, y en última instancia, la distinción entre textos\/cuerpos ?hábiles? y ?discapacitados? (McSweeney, Goransson, 2008) y conformar un aporte para las teorías queer y la traducción queer (Spurlin), en un contexto donde cada vez se abren más espacios para discutir estas nociones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239216,"idioma_id":4,"titulo":"Resistance of Fusarium poae in Arabidopsis leaves requires mainly functional JA and ET signaling pathways","resumen":"Fusarium poae has been considered as a minor species among those that cause the FHB disease but in recent years several researchers have documented a high frequency of occurrence in several crops such as wheat and barley. Evaluating the interaction between Fusarium poae with the model plant Arabidopsis thaliana will contribute to the knowledge about plant defense against this pathogen. We evaluated the ability of F. poae to produce symptoms in Arabidopsis thaliana leaves by using two different methods. Moreover, we analyzed the defense of A. thaliana against F. poae using SA, JA and ET mutants and we monitored the expression level of genes involved in the main signaling pathways related to plant defense. Symptoms were observed in the inoculated leaves which allow demonstrating, as a first step, the ability of F. poae to infect A. thaliana leaves. Moreover, the results demonstrated that the npr1-1 mutants presented low symptoms compared to Col-0, etr2-1 and coi1-1 and that the coi1-1 mutant was the most susceptible genotypes followed by etr2-1 genotypes. The RT-PCR of several genes involved in plant defense revealed that PDF1.2, CHI\/PR3 and ERF1, three important JA-ET responsive genes and NPR1 and PR1, which are regulated by SA signaling, were expressed upon F. poae inoculation. Our results suggest that JA and ET could play a key role in Arabidopsis leaves defense against F. poae. Therefore, although SA responsive genes were expressed in the inoculated leaves compared to control, the low symptoms observed in npr1-1 mutants indicate that functional SA would not be required for plant defense to F. poae. In conclusion, our results represent the first evaluation of the response of the main A. thaliana phytohormones involved in plant defense in the presence of F. poae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239217,"idioma_id":4,"titulo":"Learning path based-portfolio for personalized learning","resumen":"Nowadays, lot of human activities have been affected by the use of technology needed to change in order to adapted. Particularly, in education domain the changes that occurred were not enough to break the traditional schemas of teaching. In this way, more and more people claim for real remodeling. Mainly, one of the most important subject is the necessity to adapt the teaching process to the particular characteristics of students, in a king of personalized learning. This work presents a conceptual framework, which proposes learning path based-portfolio as a way to personalize education. This framework uses semantic technologies, logical rules and agents to determine the student learning level and based on that propose course of actions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239218,"idioma_id":4,"titulo":"Behavioural flexibility does not prevent numerical declines of harvester ants under intense livestock grazing: responses of harvester ants to habitat degradation","resumen":"1. Human-induced rapid environmental change may decrease food resourcesand create unfavourable conditions for native species. Organisms showing a flexible foraging behaviour can exploit novel or alternative foods and are more likely to persist, whereas less flexible organisms might suffer starvation and numerical reductions.2. This study assessed whether declines in the quality and availability of seedsprompted by grazing provoke behavioural and numerical responses in Pogonomyrmexmendozanus ants, and aimed to test whether behavioural flexibility buffers habitat degradation and prevents numerical declines.3. Heavy grazing caused seed reductions, especially of the highly consumed andpreferred grass seeds, and triggered two kinds of ant responses. Ants expanded their diet by incorporating a greater proportion of non-seed items, and they reduced foraging activity. As a consequence, the rate of food intake per colony lessened, particularly that of carbohydrate-rich seeds like grass seeds. Colony density under heavy grazing also fell.4. Habitat degradation triggered a cascade of mechanisms that starts with a decrease in the seed resources and continues with changes in ant behaviour. However, behavioural responses were insufficient to prevent ant numerical declines. The results of this study suggest that the reduction in the colony density under habitat degradation was provoked by ant nutritional deficit and starvation, and predict a deterioration in body condition, colony performance and reproduction of ants, which deserve further assessment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239219,"idioma_id":4,"titulo":"Diet switching of seed-eating birds wintering in grazed habitats of the central Monte Desert, Argentina","resumen":"Although bird population declines associated with land degradation are common, the initial response of organisms to rapid human-induced environmental change is usually behavioral. Reductions in seed availability due to cattle grazing may trigger diet switching in seed-eating birds, but empirical examples of such behavior are lacking. We asked whether cattle grazing changed the composition and reduced the size of seed reserves, and whether seed shortage caused diet shifts in 4 species of seed-eating birds wintering in the central Monte Desert, Argentina. We assessed the soil seed bank composition and the granivorous fraction of each species´ diet. Digestive tract or crop contents were obtained by using the flushing method on individuals captured with mist nets, and seeds were sorted and assigned to 1 of 3 functional groups (small grass seeds, large and medium-sized grass seeds, or forb seeds). Cattle grazing reduced the abundance of the preferred large and medium-sized grass seeds by 60?90%. The grass-seed specialists Many-colored Chaco Finch (Saltatricula multicolor) and Ringed Warbling-Finch (Microspingus torquatus) did not change their diets in grazed areas, but the expanding specialists Common Diuca-Finch (Diuca diuca) and Rufous-collared Sparrow (Zonotrichia capensis) incorporated increased proportions of small grass seeds as well as forb seeds into their diets. These results were correctly predicted from species-specific differences in feeding flexibility previously established in cafeteria experiments. Based on species-specific diet composition, the energy reward of seeds by unit mass consumed decreased moderately (5?21%) in the grazed sites for S. multicolor, M. torquatus, and D. diuca. Starch content was similar between grazing conditions for all 3 birds. Although such deficits might be compensated for by a slight increase in absolute mass of seeds or alternative food items consumed in degraded lands, substantial reduction in the availability of grass seeds may reduce the capacity of degraded lands to support specialist granivorous birds.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239220,"idioma_id":5,"titulo":"SIMULACIÓN DE LA EYECCIÓN DE SPRAY LÍQUIDO DESDE UN PICO DE PULVERIZADORA PARA APLICACIÓN DE HERBICIDAS","resumen":"El presente trabajo muestra los resultados preliminares de la simulación computacional de la eyección de spray líquido desde un pico de pulverización tipo HARDI? utilizado comúnmente en las aplicaciones de herbicidas que se realizan en cultivos extensivos de zonas rurales. Primero se realizó la simulación de fluido confinado con el fin de determinar el perfil de velocidad del líquido a la salida del pico de pulverización. Luego se utilizó el código acoplado LES-STO (Simulación de los Grandes Vórtices ? Modelo Estocástico Lagrangiano) para simular la trayectoria de las partículas en estado líquido desde el mismo y hasta el suelo en condiciones de aire calmo y suelo plano. En este último código se implementaron algoritmos para la simulación de los diámetros de gotas, sus velocidades y trayectorias, considerándolas como partículas líquidas. Se presenta un algoritmo de eyección aleatoria de gotas de diferentes diámetros cuya función de densidad de probabilidad ajusta a una distribución Weibull con dos parámetros. Éstos son ajustados previamente utilizando datos de mediciones experimentales en laboratorio. Para la simulación de las trayectorias se tuvo en cuenta la presión de salida del líquido, temperatura, propiedades físicas y altura de aplicación. Los procesos micro-físicos de coalescencia-ruptura y evaporación-condensación no son simulados en este trabajo. Se contrastaron los tamaños de gotas simulados con los observados experimentalmente y con los que surgen de la distribución de Weibull con excelentes coeficientes de correlación. Se obtuvieron además las trayectorias de las partículas en las condiciones de medición en laboratorio. Se observa que las velocidades de sedimentación, coeficientes de arrastre y tiempos característicos de relajación de las partículas líquidas simuladas ajustan bien a los datos experimentales. Se confirma además que las partículas líquidas menores a 50 micrómetros alcanzan rápidamente su velocidad de sedimentación antes de llegar al suelo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239221,"idioma_id":5,"titulo":"Asociaciones macrobentónicas con presencia de mitílidos de la bahía San Julián (Patagonia austral, Argentina).","resumen":"The macrobenthic assemblages with mytilids of San Julián bay (Southern Patagonia, Argentina) were sampled insummer 2007 to know its structure, diversity and distribution, and to determine their relationship to different environmentalfactors. The study was conducted in 3 locations with different types of substrate and slope. Sampling at each site was performedin a transect to cover different levels of intertidal and shallow subtidal. A total of 46 species belonging mainly to molluscs (20),crustaceans (12) and polychaetes (10) were found. Three main macrofaunal assemblages were identified. Platynereis-Clunio-Darina assemblage was distributed in the upper intertidal of muddy and gentle slopes substrate, and had the lowest values ofnumber of species, diversity and abundance of individuals. The Mytilus-Perumytilus assemblage was distributed in the middle andlower intertidal levels in rocky substrate or muddy substrate with abundant support elements and medium slope. This assemblagepresented intermediate values of diversity and greater abundance of individuals. The Aulacomya-Exosphaeroma assemblage hadthe highest number of species and the greatest diversity, but low abundance of individuals, being related to rocky substrate ormuddy substrate with support elements and low slopes in the upper subtidal. Species richness and diversity of these assemblagesincreases from the upper intertidal to subtidal, possibly because of a complex gradient of stress, mainly caused by desiccationand exposure to extreme temperatures.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239224,"idioma_id":4,"titulo":"Synthesis of Gadolinium-based Nanostructures Through an Enzymatic Liposome-controlled Reaction","resumen":"The success of synthesis of varied nanostructures requires the precise precipitation of materials at particular location. Here, gadolinium carbonate nanocapsules or macroporous structures have been successfully synthesized via interplay control on enzymatic precipitation and liposome templating. The nanostructures reflected the shape of the liposomes, where spherical 560 nm size and porous architectures with large pores of 200?300 nm diameter (corresponding to sections along liposomes) ensembles were formed. The manipulation over location of ureases in the liposome system and the temperature-actuated vesicle permeability were crucial factors in determining the morphology of the final product. This liposome-directed enzymatic precipitation represents a powerful yet facile method for lanthanide-based nanostructures synthesis for promising applications.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239225,"idioma_id":4,"titulo":"On the stability of nucleoside diphosphate glucose metabolites: implications for studies of plant carbohydrate metabolism","resumen":"Nucleoside diphosphate sugars (NDP-sugars) are the substrates for biosynthesis of oligo- and polysaccharides, such as starch and cellulose, and are also required for biosynthesis of nucleotides, ascorbic acid, several cofactors, glycoproteins and many secondary metabolites. A&nbsp;controversial study that questions the generally accepted pathway ofADP-glucose and starch synthesis in plants is based, in part, on claims that NDP-sugars areunstable at alkaline pH in the presence of Mg2+ and that this instability can lead to unreliable results from in vitro assays of enzyme activities. If substantiated, this claimwould have far-reaching implications for many published studies that report on the activitiesof NDP-sugar metabolizing enzymes. To resolve this controversy, we investigated the stability of UDP- and ADP-glucose using biophysical, namely nuclear magnetic resonance(NMR), and highly specific enzymatic methods. Results obtained with both techniques indicate that NDP-sugars are not as unstable as previously suggested. Moreover, their calculated in vitro half-lives are significantly higher than estimates of their in plantaturnover times. This indicates that the physico-chemical stability of NDP-sugars has little impact on their concentrations in vivo and that NDP-sugar levels are determined primarilyby the relative rates of enzymatic synthesis and consumption. Our results refute one of the main arguments for the controversial pathway of starch synthesis from imported ADP-glucose produced by sucrose synthase in the cytosol.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239226,"idioma_id":4,"titulo":"Simulating competitive egress of noncircular pedestrians","resumen":"We present a numerical framework to simulate pedestrian dynamics in highly competitive conditions by means of a force-based model implemented with spherocylindrical particles instead of the traditional, symmetric disks. This modification of the individuals´ shape allows one to naturally reproduce recent experimental findings of room evacuations through narrow doors in situations where the contact pressure among the pedestrians was rather large. In particular, we obtain a power-law tail distribution of the time lapses between the passage of consecutive individuals. In addition, we show that this improvement leads to new features where the particles´ rotation acquires great significance.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239227,"idioma_id":4,"titulo":"Pedestrian collective motion in competitive room evacuation","resumen":"When a sizable number of people evacuate a room, if the door is not large enough, an accumulationof pedestrians in front of the exit may take place. This is the cause of emerging collective phenomena where the density is believed to be the key variable determining the pedestrian dynamics. Here, we show that when sustained contact among the individuals exists, density is not enough to describethe evacuation, and propose that at least another variable ?such as the kinetic stress? is required.We recorded evacuation drills with different degrees of competitiveness where the individuals are allowed to moderately push each other in their way out. We obtain the density, velocity and kinetic stress fields over time, showing that competitiveness strongly affects them and evidencing patterns which have been never observed in previous (low pressure) evacuation experiments. For the highest competitiveness scenario, we detect the development of sudden collective motions. These movements are related to a notable increase of the kinetic stress and a reduction of the velocity towards the door, but do not depend on the density.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239228,"idioma_id":5,"titulo":"'La 'dialéctica' del habla y de la escritura en la hermenéutica de Paul Ricoeur. Un estudio crítico'","resumen":"Presentadas las distintas posiciones asumidasfrente a la relación entre oralidad y escritura en el dominio de las cienciashumanas, la hipótesis es que más que una ?dialéctica? en sentido propio, PaulRicoeur comparte con el fonocentrismo el carácter de fijación que proveela escritura a una instancia de habla originaria y con el autonomismo lairreductibilidad de la escritura al habla viva. Un autonomismo que gira haciael grafocentrismo al conferir a la escritura la representación integraldel discurso y reivindicar el textocentrismo dominante en las teoríasestéticas de la lectura, lo que deviene una diminutio capitis de laoralidad. Esto provocaría problemas internos a la hermenéutica ricoeuriana, asaber: el devenir-consciente: el diálogo analítico;&nbsp; la poética del sí mismo: la identidadnarrativa; el mantenimiento del ipse: la promesa.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239229,"idioma_id":4,"titulo":"Designed nanoparticle-mesoporous multilayer nanocomposites as tunable plasmonic-photonic architectures for electromagnetic field enhancement","resumen":"In this work we present the designed production of a highly tunable nanocomposite able to confine and enhance the electromagnetic field through the combined effects of photonic and plasmonic responses. Silver nanoparticles (NPs) were embedded within a Mesoporous Photonic Crystal (MPC) composed of a mesoporous multilayer presenting a TiO2-SiO2 unit cell. This nanosystem was synthesized by a combination of reproducible sol-gel thin film techniques with the selective production of NPs within the titania layers. The design of the MPC architecture was tuned so that each photonic band gap edge would match the plasmonic absorption peak of the Ag NP, in order to combine their confined plasmonic enhancement with that of the band gap edges due to the multilayer structure. We find that the MPC contributes to enhancing the Surface Enhanced Raman Scattering (SERS) signal of probe molecules trapped in the mesopores. This effect indicates the relevance of the unit cell interfaces for the local electromagnetic field enhancements, and opens the gate to performing plasmon-assisted SERS sensing. The resulting material results in a promising platform to study the interplay between photonic and plasmonic systems. These tuneable nano-architectures are highly robust, reproducible, and can lead to applications in sensing platforms, as well as in optoelectronics, enhanced photocatalysis, or artificial photosynthesis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239230,"idioma_id":4,"titulo":"Mesoporous thin film structures as metal nanoparticle reactors for electronic circuits: Effects of matrix crystallinity and nanoparticle functionalization","resumen":"There is an increasing interest in versatile nanoelectronic structures based on stable, accessible and spatially located arrays of metal nanoparticles. In this study, the influences of mesoporous titania thin film crystallinity and pore features over electrical conductivity of embedded Ag-nanoparticles were analyzed. Although matrices treated at lower temperatures have shown less pore connectivity, less extensive anatase fraction and lower silver content, they revealed higher electrical conductivity than matrices treated at higher temperatures. This was interpreted as better connectivity among particles from plasmon behavior. The stability of this system was significantly enhanced through upon chemisorption of 1-octanethiol self-assemble monolayers over Ag-nanoparticles. The maximum plasmon absorbance remained practically unaltered after storage for at least 15 days and the current remains stable up to 20 voltage cycles. This demonstrates that a stable and accessible conductive nanocomposite circuit consisting of alkanethiol-functionalized metal nanoparticles embedded in a mesoporous oxide thin film matrix can be produced.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239231,"idioma_id":4,"titulo":"Analysis of NDVI, SAVI and MSAVI2 indices in relation of the ground elevation in Crespo, Entre Ríos.","resumen":"The advances in geospatial technology, remote sensing, geographical information systems and GPS have made possible many and new analysis of digital elevation models (MDE) and the images obtained by remote sensing. The vegetation indexes obtained from the images and the MDE products allow progress in the understanding of the interaction between these indices and the characteristics of the terrain. The present work has as objective to verify the behavior of the indices NDVI, SAVI and MSAVI2 depending on the height of the ground in the area covered by the topographic map of the IGN (sheet number 3360-3-1; Scale: 1:50000), to the south of the Department Paraná in the Province of Entre Rios (Argentina). The digital elevation model was developed from the level curves of the digitized topographic Charter. The terrain was categorized as low, medium and high according to 3 class intervals close to 33% each. The vegetation indexes, were obtained from the  Operational Land Imager (OLI) sensor of Landsat 8 for the day 22 February 2016. For the analysis of the vegetation indexes, in the different categories of height, were vectorized 30 polygons of lots as training sites that - according to the photointerpretation - correspond to batches with crops. With these polygons are extracted data from the indexes for the statistical analysis. A test was conducted to check the difference of averages of the samples for the 3 classes. The results indicate that there are significant differences (n = 30, p <0.05) between the mean NDVI of different categories of MDE. On the other hand the SAVI and MSAVI2 indices show no significant difference when the middle and upper categories are analyzed. It was found that the highest values of 3 index correspond to higher height values according to MDE. In turn, the lowest rates were in areas of lower altitude. It is concluded that in the study area and for summer crops, NDVI, SAVI and MSAVI2 indices could be affected by terrain height","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239232,"idioma_id":5,"titulo":"Ipseidad y estructura dialógica en la filosofía de Karl-Otto Apel","resumen":"El presente artículo aborda el problema de la identidad y la otredad en la filosofía de Karl-Otto Apel, teniendo en cuenta que la estructura dialógica de la racionalidad permite pensar más allá de la filosofía tradicional de la conciencia. De acuerdo con este objetivo, se emplean las categorías de ipseidad y mismidad, propuestas por Paul Ricoeur, a modo de instrumento metodológico, para realizar una lectura de la obra de Apel respecto al problema planteado. Así, pues, el posicionamiento de Apel en relación a la dialogicidad y la intersubjetividad, pone de manifiesto la importancia de la argumentación colectiva en la configuración de una identidad a modo de ipseidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239233,"idioma_id":4,"titulo":"New hadrosaurid remains from the Late Cretaceous of Río Negro Province (Argentina, Late Cretaceous)","resumen":"Purpose Although the hadrosaurid record is more abundantin theNorthernHemisphere than in the SouthernHemisphere,it is in Argentina that most remains have been discovered,specifically in Patagonia. This record is characterized by anextensive geographical distribution of sites, some of themwith abundant remains, many of which have been assigned toa high taxonomic level as indeterminate hadrosauroids orhadrosaurids. Despite the abundance of indeterminateremains, three hadrosaurid species are recorded between R&#305;´oNegro, La Pampa and Chubut provinces.Method Here, new cranial and postcranial remains fromindeterminate hadrosauroids, hadrosaurids andeuhadrosaurians deposited in several museums R&#305;´o NegroProvince are presented and described here.Results and Conclusions These new remains increase thedistribution and abundance of these dinosaurs in Argentinaand highlight the need for an in-depth revision of the historyand evolution of this ornithopod clade in South America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239235,"idioma_id":4,"titulo":"Bonapartesaurus rionegrensis , a new hadrosaurine dinosaur from South America: implications for phylogenetic and biogeographic relations with North America","resumen":"The Gondwanan hadrosaurid dinosaur record is relatively poorly known and very complicated. A newhadrosaurid, Bonapartesaurus rionegrensis, gen. et sp. nov., from the late Campanian?early Maastrichtian of the SalitralMoreno site, Argentina, is characterized by the following combination of characters: the ratio between the height of theneural spines and that of the centrum of the sacral vertebrae greater than 3.5; neural spines of the anterior section of thecaudal vertebrae extremely long and evenly expanding distally; a preacetabular process of the ilium slightly deflectedventrally, with the angle greater than 150; the ratio between the maximum dorsoventral depth of the posterior end of thepreacetabular process and the dorsoventral distance from the pubic peduncle to the dorsal margin of the ilium less than 0.50;the ratio between the dorsoventral height and anteroposterior length of the iliac blade 0.8 or greater; asymmetrical lateralprofile of the supraacetabular process; the posterior portion of the postacetabular process markedly thicker mediolaterally asa result of the dorsomedial twist of the postacetabular process; an anteriorly expanded cnemial crest restricted to theproximal end of the tibia; and articular surface of the astragalus for the internal malleolus of the tibia moderately expandedmedially, articulating with only part of the ventral surface of the tibial internal malleolus. Our phylogenetic analysis indicatesthat Bonapartesaurus is located within the Tribe Saurolophini. Paleobiogeographically, its presence suggests at least twosaurolophine dispersal events from North America, one toward South America and another toward Asia, no later than thelate Campanian.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239236,"idioma_id":5,"titulo":"Noviazgos Violentos: Un abordaje en la escuela secundaria","resumen":"El trabajo relata los pormenores de una Jornada realizada en un colegio de enseñanza media preuniversitario de la ciudad deComodoro Rivadavia, a partir de lo que se definió como un problema tras la verbalización de situaciones de noviazgos violentos en que estaban inmersas las estudiantes. Se reconstruyen las decisiones tomadas respecto de la organización y se reflexiona acerca del desarrollo de las actividades en el marco de la implementación de la Ley de Educación Sexual Integral y la tarea que tienen al respecto las instituciones educativas. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239237,"idioma_id":5,"titulo":"Porphyromonas gingivalis, patógeno de relevancia en la enfermedad periodontal","resumen":"Porphyromonas gingivalis (P.Gingivalis) es un microorganismo comprometidoen el inicio y progresión de la enfermedad periodontal crónica y agresiva,y es considerado su principal agente etiológico. Esta bacteria cuenta conuna serie defactores de virulencia que le permiten, iniciar el proceso infeccioso,perpetuar la infección y también transformar la placa dental benignaen una comunidad microbiana patógena. Estudiar sus factores de virulenciay su capacidad de modular la respuesta inmunológica del huésped es muyimportante para comprender el papel de este patógeno en el desarrollo yestablecimiento de la enfermedad. Esta revisión proporciona una visiónactual sobre los factores de virulencia y su impacto sobre la respuesta inmunológicaen relación con la patogénesis de la enfermedad periodontal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239238,"idioma_id":4,"titulo":"Phenolic Compounds Profiling of Virgin Olive Oils from Different Varieties Cultivated in Mendoza, Argentina, by Using Liquid Chromatography&ndash;Mass Spectrometry","resumen":"The aim of this work was to achieve a preliminary characterization of the profile of the phenolic fraction of virgin olive oils (VOOs) from Maipú (Mendoza, Argentina). Thus, 25 commercial VOO samples from Arauco, Arbequina, Picual, Frantoio, Changlot, Empeltre, Nevadillo, Manzanilla and Coratina (both monovarietals and blends) were analyzed using LC-ESI-QTOF MS and LC-ESI-IT MS for identification and quantification purposes, respectively. A rapid LC method (15 min) accomplished quantitative information about a total of 40 phenolic compounds, including secoiridoid derivatives, which have not been evaluated before in samples coming from the sub-region so-called Maipú (Mendoza province, Argentina). The results make evident that olive oils coming from Mendoza can be considered as important sources of phenolic bioactive compounds, exhibiting similar phenolic compounds levels to those shown by oils from other typical world production regions. Moreover, some distinctive features of Arauco variety (Argentinean autochthonous variety) were pointed out; indeed, a correlation between flavonoids content and botanical variety was established herewith.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239239,"idioma_id":4,"titulo":"Metabolic profiling approach to determine phenolic compounds of virgin olive oil by direct injection and liquid chromatography coupled to mass spectrometry","resumen":"A LC?MS method involving direct injection of extra-virgin olive oil (EVOO) ? after a simple dilution ? for determining its phenolic compounds has been developed. Optimization of the most appropriate solvent for sample dilution, selection of the optimum oil\/solvent ratio, and establishment of column cleaning strategy and maximum number of injections were some of the most relevant steps. Then, the analytical parameters of the method were evaluated, establishing LOD (from 3.3 to 31.6 µg\/L) and LOQ, precision (RSD values for inter-day repeatability were found between 3.49 and 6.12%), and trueness (within the range 89.9?102.3% for 1.0 mg\/L) and checking possible matrix effect (which was no significant). Three kinds of calibration were used: external standard, standard addition and calibration in a phenols-free matrix, which was subsequently applied to quantify the phenolic compounds in 16 EVOOs (from 6 cultivars). A total of 21 compounds were determined without the need of using any extraction protocol.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239240,"idioma_id":5,"titulo":"Ansiedad laboral: su relación con la personalidad y su impacto en las posibilidades de ejercer roles de liderazgo","resumen":"El constructo de la ansiedad laboral busca identificar diferencias individuales en el modo en que la ansiedad puede afectar el desempeño en el área del trabajo. El objetivo del presente estudio es investigar su relación con las dimensiones básicas de la personalidad, en particular, su asociación con variables interpersonales (por ej. asumir roles de liderazgo). 204 trabajadores de la Ciudad de Buenos Aires y 74 pacientes de una clínica de Trastornos de Ansiedad de la Ciudad de Buenos Aires (también trabajadores al momento del estudio) completaron el Inventario de Ansiedad en el Ámbito Laboral, y el NEO-FFI. Se recolectó también información acerca de variables relacionadas al trabajo.Se hallaron diferencias estadísticamente significativas en la subescala de Ansiedad Social y Búsqueda de Reaseguros, en particular los sujetos que no tienen gente a cargo puntúan más alto, tanto para la muestra clínica, como no-clínica. En relación a la personalidad de los líderes, bajo Neuroticismo y alta Responsabilidad permitió diferenciar a la población general de la muestra clínica. Adicionalmente, la Extroversión apareció como una dimensión que diferenciaría dentro de la muestra clínica a aquellos con gente a cargo de los que no.Puede concluirse que los trabajadores que  poseen un Perfil Ansioso Social y Buscador de Reaseguros en el Trabajo tienen significativamente menos chances de liderar grupos con las consecuencias que ello pudiera acarrear en su desarrollo profesional\/laboral.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239241,"idioma_id":4,"titulo":"Numerical evidence of hyperscaling violation in wetting transitions of the random-bond Ising model in d=2 dimensions","resumen":"We performed extensive simulations of the random-bond Ising model confined between walls where competitive surface fields act. By properly taking the thermodynamic limit we unambiguously determined wetting transition points of the system, as extrapolation of localization-delocalization transitions of the interface between domains of different orientation driven by the respective fields. The finite-size scaling theory for wetting with short-range fields [E. V. Albano and K. Binder, Phys. Rev. Lett. 109, 036101 (2012)PRLTAO0031-900710.1103\/PhysRevLett.109.036101] establishes that the average magnetization of the sample, with critical exponent &beta;, is the proper order parameter for the study of wetting. While the hyperscaling relationship given by &gamma;+2&beta;=&nu; +&nu; requires &beta;=1\/2 (&gamma;=4, &nu; =3, and &nu; =2), the thermodynamic scaling establishes that &Delta;s=&gamma;+&beta;, which in contrast requires &beta;=0 (&Delta;s=4), where &gamma;, &nu;, &nu;, and &Delta;s are the critical exponents of the susceptibility, the correlation lengths parallel and perpendicular to the interface, and the gap exponent, respectively. So, we formulate a finite-size scaling theory for wetting without hyperscaling and perform numerical simulations that provide strong evidence of hyperscaling violation (i.e., &beta;=0) and a direct measurement of the susceptibility critical exponent &gamma;\/&nu; =2.0&plusmn;0.2, in agreement with theoretical results for the strong fluctuation regime of wetting transitions with quenched noise.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239242,"idioma_id":4,"titulo":"Assessing the varietal origin of extra-virgin olive oil using liquid chromatography fingerprints of phenolic compound, data fusion and chemometrics","resumen":"High Performance Liquid Chromatography (HPLC) with diode array (DAD) and fluorescence (FLD) detection was used to acquire the fingerprints of the phenolic fraction of monovarietal extra-virgin olive oils (extra-VOOs) collected over three consecutive crop seasons (2011\/2012-2013\/2014). The chromatographic fingerprints of 140 extra-VOO samples processed from olive fruits of seven olive varieties, were recorded and statistically treated for varietal authentication purposes. First, DAD and FLD chromatographic-fingerprint datasets were separately processed and, subsequently, were joined using 'Low-level' and 'Mid-Level' data fusion methods. After the preliminary examination by principal component analysis (PCA), three supervised pattern recognition techniques, Partial Least Squares Discriminant Analysis (PLS-DA), Soft Independent Modeling of Class Analogies (SIMCA) and K-Nearest Neighbors (k-NN) were applied to the four chromatographic-fingerprinting matrices. The classification models built were very sensitive and selective, showing considerably good recognition and prediction abilities. The combination 'chromatographic dataset+chemometric technique' allowing the most accurate classification for each monovarietal extra-VOO was highlighted.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239258,"idioma_id":5,"titulo":"La revolución sexual antes de la revolución sexual. Discursos de los médicos libertarios sobre el placer (Argentina, 1930-1940)","resumen":"Resumen: Este artículo indaga las narrativas médicas ácratas referidas al placer sexual en Argentinadurante los años treinta y cuarenta del s. XX. El abordaje de las intervenciones de losmédicos Juan Lazarte y Manuel Martín Fernández nos permite matizar periodizaciones enrelación con el discurso sexológico y la Revolución Sexual. Lazarte y Fernández, que participabandel movimiento anarquista, defendieron la legitimidad del placer sexual independientede la reproducción, y se opusieron a la institución matrimonial, y a la prostitución, comoúnicos ámbitos aceptados para el ejercicio sexual. Es decir, anticiparon propuestas que fueronlos ejes centrales de la Revolución Sexual de los años 1960. Asimismo, al definir los vínculossexuales, recrearon exclusiones a partir de la matriz heterosexual de la cual partían. A travésde las herramientas del Análisis Crítico del Discurso, y desde una perspectiva de género, analizaremosdichas narrativas médicas, difundidas en libros y revistas culturales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239263,"idioma_id":5,"titulo":"Anarquismo(s) y feminismo(s). Un estudio sobre las intervenciones de las mujeres anarquistas en la prensa, Buenos Aires, 1896-1947","resumen":"En este trabajo nos interesa reflexionar sobre las conceptualizaciones que se han utilizado para identificar las ideas y prácticas de las mujeres anarquistas en Argentina desde fines de siglo XIX hasta la primera mitad del siglo XX. A partir de los criterios esbozados por Karen Offen para identificar ideas y prácticas de un sujeto feminista indagaremos tres publicaciones anarquistas escritas por mujeres: La Voz de la Mujer, Nuestra Tribuna y ?La página de la mujer? sección del periódico Reconstruir. A través del análisis visibilizaremos las continuidades e inflexiones discursivas y reflexionaremos sobre su identificación con el feminismo, teniendo en cuenta las conceptualizaciones de las propias mujeres en relación con el contexto de locución.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239265,"idioma_id":5,"titulo":"Aplicación del modelo de revaluación de la RT 31. Su incidencia en la medición del patrimonio y los resultados.","resumen":".","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239266,"idioma_id":5,"titulo":"Labor profesional en ahorro previo","resumen":"El presente artículo pretende revelar de qué modo el actuario puede colaborar con el contador en el desarrollo de su labor profesional diaria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239267,"idioma_id":5,"titulo":"Efecto reciproco de impulsividad y consumo de alcohol en adolescentes argentinos","resumen":"Introducción. Niveles más altos de impulsividad serelacionan con un incremento del consumo de alcohol y,además, el consumo de alcohol incrementa laimpulsividad y la toma de riesgos. Objetivo. Examinar,mediante un estudio longitudinal de dos mediciones, lainfluencia recíproca de impulsividad (rasgo y conductual)y de toma de riesgos sobre el posterior consumo dealcohol. Muestra. Participaron 161 adolescentes (Mediade edad=15.83±.85) de la Ciudad de Córdoba (Argentina).Procedimiento. Se realizaron dos mediciones separadaspor un periodo de tres meses. En cada una se midióconsumo de alcohol, impulsividad rasgo, inhibición derespuesta, toma de riesgos y aversión a la demora.Resultados. Los resultados evidencian una relaciónrecíproca entre impulsividad y toma de riesgos con elconsumo de alcohol. El consumo de alcohol en el Tiempo1, en especial la cantidad y frecuencia de consumoepisódico elevado, impactaron sobre una mayor toma deriesgos e impulsividad rasgo en el Tiempo 2. Asimismo,un mayor nivel de impulsividad rasgo tuvo un efectopositivo y prospectivo sobre la frecuencia y cantidad deconsumo de alcohol. Discusión. El principal hallazgo deeste trabajo es indicar, en población adolescente, y conun intervalo entre mediciones de sólo tres meses, unefecto prospectivo bidireccional positivo entre consumode alcohol, impulsividad y toma de riesgos","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239268,"idioma_id":4,"titulo":"Cross-cultural examination of college drinking culture in Spain, Argentina, and USA: Measurement invariance testing of the College Life Alcohol Salience Scale","resumen":"Objective: Perceptions about what is ?normal? drinking in college, measured by the CollegeLife Alcohol Salience Scale (CLASS; 15 items), have been robustly associated with elevatedlevels of problematic alcohol use, yet the role of these beliefs has not been studied outside theU.S. The present work examined measurement invariance of the CLASS across sex, drinkerstatus, and in individuals of three different countries (i.e., U.S., Argentina, Spain). Additionalgoals were to evaluate differences on the CLASS (i.e., latent mean differences) as a function ofsex, drinker status and country and to compare construct validity (i.e., correlations with alcoholvariables) across sex and different countries. Method: A large sample of 1,841 college studentsenrolled in universities from U.S., Spain and Argentina completed, via an online survey, abattery of instruments that assess college alcohol beliefs, drinking motives, alcohol consumptionand alcohol-related negative consequences. Results: We found that a shortened 12-item versionof the CLASS to be invariant across sex and drinker status, but only metric invariance was foundacross countries. As expected, men and drinkers showed significantly higher scores on theCLASS than women and non-drinkers, respectively. Bivariate correlations between CLASSscores and drinking outcomes strongly supported criterion-related validity of this measure acrossmultiple countries and sex with differing strengths in relationships with alcohol-relatedconstructs. Conclusions: Taken together, perceptions of the centrality of alcohol to the collegeexperience appear to be an important target for college student alcohol interventions acrossvarious cultures and countries, especially for male college student drinkers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239270,"idioma_id":4,"titulo":"ELSA 2016 cohort: Alcohol, Tobacco, and Marijuana use and their association with age of drug use onset, risk perception, and social norms in Argentinean college freshmen","resumen":"The transition from high school to college is a high-risk stage for the initiation and escalation of substance use. Substance use and its associated risk factors have been thoroughly described in developed countries, such as the United States, but largely neglected in Argentina, a South American country with patterns of a collectivist culture. The present cross-sectional study describes the occurrence of alcohol, tobacco, and marijuana use and the association between these behaviors and the age of onset of substance use and cognitive (i.e., risk perception) and social (i.e., prescriptive) variables in a large sample of Argentinean college freshmen (n D 4083, 40.1% men; mean age D 19.39 - 2.18 years). The response rate across courses was 90% and was similarly distributed across sex. Participants completed a survey that measured substance use (alcohol [with a focus on heavy drinking and binge drinking behaviors], tobacco, and marijuana), age of onset of the use of each substance, perceived risk associated with various substance use behaviors, prescriptive norms associated with substance use, and descriptive norms for alcohol use (AU). The results indicated that AU is nearly normative (90.4 and 80.3% with last year and last month use, respectively) in this population, and heavy drinking is highly prevalent (68.6 and 54.9% with heavy episodic and binge drinking, respectively), especially among those with an early drinking onset (97.8 and 93.6% with last year and last month use and 87.8 and 76.3% with heavy episodic and binge drinking, respectively). The last-year occurrence of tobacco and marijuana use was 36 and 28%, respectively. Early substance use was associated with the greater use of that specific substance. The students overestimated their same-sex friend´s AU, and women overestimated the level of AU of their best male friend. At the multivariate level, all of the predictors, with the exception of the parents´ prescriptive norms, significantly explained the frequency of marijuana and tobacco use and frequency of hazardous drinking. Overall, despite important cultural and contextual differences between Argentina and the United States, our findings suggest that certain vulnerability factors have a similar influence across these cultural contexts.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239271,"idioma_id":4,"titulo":"Importance of hydration degree in the use of clay-fungal materials as adsorbents for uranium uptake","resumen":"The development of new adsorbent materials is a key factor for applying sorption-based technologies designed to clean effluents. Clay biomass complexes (BMMT) from fungal biomass grown on a raw Montmorillonite (MMT) were generated in a previous work and used in a wet state. These samples were examined previously as a material to retain metals and improve separation after adsorption processes. The objective of this study is to characterize the uranium (VI) adsorption of previously dried BMMT, to determine differences to wet BMMT samples, and to understand some of the processes responsible for those differences. Differences between dried and wet BMMT adsorption capacities were verified. Proton exchange of dried BMMT samples was analyzed. Furthermore, X ray diffraction (XRD) and Zeta Potential measurements of samples after uranium (VI) uptake were performed. The hydration degree during the adsorption contact time was evaluated. Contact angle measurement and diffusion experiments by Fourier transform infrared spectroscopy (FTIR) were conducted, too. Dried BMMT samples presented a higher uranium (VI) uptake capacity than wet BMMT samples. Biomass played an important role in the behavior of samples evaluated and results indicated the importance to specify the hydration degree of adsorbents.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239273,"idioma_id":4,"titulo":"Thiabendazole adsorption on montmorillonite, octadecyltrimethylammonium- and Acremonium sp.-loaded products and their copper complexes","resumen":"This study is a preliminary approach to develop novel montmorillonite (Mt) based adsorbents for removing inorganic and organic contaminants in a step-like process. Biomass (fungi) and surfactant (octadecyltrimethylammonium bromide) modified montmorillonites (BMt and OMt, respectively) were obtained. In a prior step, Cu2+ was loaded into Mt, BMt and OMt. In a second step, the materials (Mt, Mt-Cu, BMt, BMt-Cu, OMt, OMt-Cu) were used as thiabendazole (TBZ) adsorbents. TBZ adsorption isotherms were performed, and Langmuir, Freundlich and Langmuir-Freundlich mathematical models were evaluated. TBZ removal efficiency of the materials was also tested using three adsorbent dosages.The adsorbents and TBZ-adsorbed products were characterized by X-ray diffraction and thermal analysis, and by electron paramagnetic resonance (EPR) and solid-state nuclear magnetic resonance measurements (ss-NMR). To determine the subsequent arrangement of the adsorption products, leaching experiments were also conducted.In the BMt sample, TBZ adsorption was enhanced compared to the raw Mt sample. An opposite behaviour was observed for OMt samples. All the Cu2+-loaded materials showed better TBZ removal efficiencies than the same materials without Cu2+. Furthermore, Cu2+ chelation through the imidazolic and thiazolic nitrogen atoms of TBZ in all Cu2+-loaded samples allowed TBZ and Cu2+ to be resistant to migration in environmental leaching conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239274,"idioma_id":5,"titulo":"Repensando la programación como formación práctica en Ingeniería: Un estudio de caso en primer año","resumen":"En el presente trabajo se analiza una experiencia llevada adelante en el marco de la actividad curricular ?Introducción a la Ingeniería Mecánica? de la Facultad de Ciencias Exactas, Ingeniería y Agrimensura de la Universidad Nacional de Rosario, Argentina. Dicha asignatura integra una modalidad pedagógica de taller, enfatizando la formación práctica en el marco de las actuales políticas latinoamericanas de fortalecimiento de la formación de ingenieros. En este contexto, se propuso la realización de un proyecto final integrador con el objetivo de introducir al alumnado en la resolución de problemas abiertos de ingeniería, proponiendo como consigna la simulación de un sistema mecánico sencillo en un entorno de programación por bloques. Desde un estudio de caso exploratorio con metodología mixta, el artículo expone un análisis de esta experiencia piloto, indagando en las formas en que los participantes se aproximaron al ejercicio propuesto e identificando problemáticas derivadas de la construcción de la simulación. Los resultados mostraron el logro de los objetivos planteados en el taller y evidenciaron el potencial que posee la programación para el fortalecimiento de habilidades vinculadas a la enseñanza práctica. Por otra parte, la mejora de otros aspectos como el trabajo en grupo unido al autoaprendizaje, introducen cambios iniciales en los hábitos de los ingresantes para la resolución de problemas. En síntesis, la experiencia aporta evidencias en torno al potencial de la modalidad de taller para incluir tecnologías dentro de la formación práctica de futuros ingenieros, permitiendo el desarrollo de diferentes habilidades destacadas por las políticas universitarias vigentes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239275,"idioma_id":5,"titulo":"Modelado y simulación de un sistema mecánico simple: programar en primer año de ingeniería","resumen":"El trabajo presenta un análisis exploratorio del proceso deconstrucción de simulaciones de un sistema mecánico utilizando entornos deprogramación con bloques por parte de alumnos universitarios. Los resultadosprovienen de un estudio de caso desarrollado en la asignatura de primer año?Introducción a la Ingeniería Mecánica? (Facultad de Ingeniería, UNR).Partiendo del modelado, los participantes diseñaron, programaron y evaluaronsus propias simulaciones utilizando Scratch, que resultó un recurso idóneo paraser utilizado con estudiantes con escasos conocimientos de programación. Deesta forma, las simulaciones funcionaron como una herramienta deaprendizaje en una etapa temprana de la carrera. Los resultados reflejan lanecesidad de propiciar propuestas educativas que permitan el estudio de losdiversos aspectos del modelado, la simulación y la programación en carrerasde ingeniería, ya que estas experiencias pueden facilitar el uso de entornosmás específicos y potentes, siendo recursos valiosos para enriquecersituaciones curriculares y profesionales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239276,"idioma_id":4,"titulo":"The riboflavin-photosensitized degradation of the uv -absorbing azo dye-metabolites Benzidine and o -Tolidine. Kinetic and mechanistic aspects","resumen":"The visible-light-promoted photodegradation of two carcinogenic primary azo-dye metabolites (BZ-C), represented by the colourless water-contaminants Benzidine (BZ) and o-Tolidine (OT), was studied in water-methanol solution. It was done in the presence of air and the natural pigment riboflavin (Rf) as a photosensitizer. These conditions reasonably mimic a natural environment scenery. Both BZ-C interact with the reactive oxygen species (ROS) singlet molecular oxygen (O2(1&#916;g)), superoxide radical anion (O2[rad]?), hydrogen peroxide (H2O2) and hydroxyl radical (OH[rad]), all photogenerated in situ through energy-transfer and electron-transfer processes. The interaction of BZ-C with O2(1&#916;g) is essentially physical in nature and occurs with a relatively high rate constant value. The effective BZ-C degradation is mainly driven by the remaining photogenerated ROS. A comparison of the BZ and OT photooxidative-rate with those of the archetypal surface-water-contaminants aniline and phenol indicates that BZ-C degradation occurs in a moderately slower fashion than the reference contaminants, within a common overall time-scale. The primary photoprocesses initiating the Rf-sensitized degradation seems to be quite similar for the four compounds, with the simultaneous operation of Type I and Type II photoprocesses. In conclusion: the natural Rf- photosensitized degradation of BZ-C appears as a plausible process, as evaluated under simulated environmental conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239277,"idioma_id":4,"titulo":"Assigning ecological roles to the populations belonging to a phenanthrene-degrading bacterial consortium using omic approaches","resumen":"The present study describes the behavior of a natural phenanthrene-degrading consortium (CON), a synthetic consortium (constructed with isolated strains from CON) and an isolated strain form CON (Sphingobium sp. AM) in phenanthrene cultures to understand the interactions among the microorganisms present in the natural consortium during phenanthrene degradation as a sole carbon and energy source in liquid cultures. In the contaminant degradation assay, the defined consortium not only achieved a major phenanthrene degradation percentage (> 95%) but also showed a more efficient elimination of the intermediate metabolite. The opposite behavior occurred in the CON culture where the lowest phenanthrene degradation and the highest HNA accumulation were observed, which suggests the presence of positive and also negative interaction in CON. To consider the uncultured bacteria present in CON, a metagenomic library was constructed with total CON DNA. One of the resulting scaffolds (S1P3) was affiliated with the Betaproteobacteria class and resulted in a significant similarity with a genome fragment from Burkholderia sp. HB1 chromosome 1. A complete gene cluster, which is related to one of the lower pathways (meta-cleavage of catechol) involved in PAH degradation (ORF 31?43), mobile genetic elements and associated proteins, was found. These results suggest the presence of at least one other microorganism in CON besides Sphingobium sp. AM, which is capable of degrading PAH through the meta-cleavage pathway. Burkholderiales order was further found, along with Sphingomonadales order, by a metaproteomic approach, which indicated that both orders were metabolically active in CON. Our results show the presence of negative interactions between bacterial populations found in a natural consortium selected by enrichment techniques; moreover, the synthetic syntrophic processing chain with only one microorganism with the capability of degrading phenanthrene was more efficient in contaminant and intermediate metabolite degradation than a generalist strain (Sphingobium sp. AM).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239278,"idioma_id":4,"titulo":"Comparative and functional triatomine genomics reveals reductions and expansions in insecticide resistance-related gene families","resumen":"(Sheila Ons y Rolando Rivera Pomar son co-autores de correspondencia del presente trabajo). Background: Triatomine insects are vectors of Trypanosoma cruzi, a protozoan parasite that is the causative agent of Chagas disease. This is a neglected disease affecting approximately 8 million people in Latin America. The existence of diverse pyrethroid resistant populations of at least two species demonstrates the potential of triatomines to develop high levels of insecticide resistance. Therefore, the incorporation of strategies for resistance management is a main concern for vector control programs. Three enzymatic superfamilies are thought to mediate xenobiotic detoxification and resistance: Glutathione Transferases (GSTs), Cytochromes P450 (CYPs) and Carboxyl\/Cholinesterases (CCEs). Improving our knowledge of key triatomine detoxification enzymes will strengthen our understanding of insecticide resistance processes in vectors of Chagas disease.&nbsp; Methods and Findings: The discovery and description of detoxification gene superfamilies in normalized transcriptomes of three triatomine species: Triatoma dimidiata, Triatoma infestans and Triatoma pallidipennis is presented. Furthermore, a comparative analysis of these superfamilies among the triatomine transcriptomes and the genome of Rhodnius prolixus, also a triatomine vector of Chagas disease, and other well-studied insect genomes was performed. The expression pattern of detoxification genes in R. prolixus transcriptomes from key organs was analyzed. The comparisons reveal gene expansions in Sigma class GSTs, CYP3 in CYPs superfamily and clade E in Carboxyl\/Cholinesterase superfamily. Moreover, several CYP families identified in these triatomines have not yet been described in other insect . Conversely, several groups of insecticide resistance related enzymes within each enzyme superfamily are reduced or lacking in triatomines. Furthermore, our qRT-PCR results showed an increase in the expression of a CYP4 gene in a T. infestans population resistant to pyrethroids. These results could point to an involvement of metabolic detoxification mechanisms on the high levels of pyrethroid resistance detected in triatomines from the Gran Chaco ecoregion.Conclusions and Significance: &nbsp;Our results help to elucidate the potential insecticide resistance mechanisms in vectors of Chagas disease and provide new relevant information for this field. This study shows that metabolic resistance might be a contributing cause of the high pyrethroid resistance observed in wild T. infestans populations from the Gran Chaco ecoregion, areas that although subjected to intense pyrethroid treatments, vector control has failed. This study opens new avenues for further functional studies on triatomine detoxification mechanisms. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239280,"idioma_id":4,"titulo":"Lateral Antimicrobial Resistance Genetic Transfer is active in the open environment","resumen":"Altmetric: 14More detailArticle | OPENLateral Antimicrobial Resistance Genetic Transfer is active in the open environmentLuciana S. Chamosa, Verónica E. Álvarez, Maximiliano Nardelli, María Paula Quiroga, Marcelo H. Cassini & Daniela CentrónScientific Reports 7, Article number: 513 (2017)doi:10.1038\/s41598-017-00600-2Download CitationAntimicrobial resistanceMicrobial ecologyReceived:28 October 2016Accepted:27 February 2017Published online:31 March 2017AbstractHistorically, the environment has been viewed as a passive deposit of antimicrobial resistance mechanisms, where bacteria show biological cost for maintenance of these genes. Thus, in the absence of antimicrobial pressure, it is expected that they disappear from environmental bacterial communities. To test this scenario, we studied native IntI1 functionality of 11 class 1 integron-positive environmental strains of distant genera collected in cold and subtropical forests of Argentina. We found natural competence and successful site-specific insertion with no significant fitness cost of both aadB and blaVIM-2 antimicrobial resistance gene cassettes, in a model system without antibiotic pressure. A bidirectional flow of antimicrobial resistance gene cassettes between natural and nosocomial habitats is proposed, which implies an active role of the open environment as a reservoir, recipient and source of antimicrobial resistance mechanisms, outlining an environmental threat where novel concepts of rational use of antibiotics are extremely urgent and mandatory.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239281,"idioma_id":5,"titulo":"Entrevista con Expertos: Matig Mavissakalian","resumen":"El Dr. Matig Mavissakalian es uno de los expertos internacionales más reconocidos por sus aportes a la teoría, investigación y tratamiento de los Trastornos de Ansiedad. Actualmente lleva adelante su práctica clínica en el Departamento de Psiquiatría del University Hospitals ? Cleveland Medical Center. Durante la década de los 70 y 80´s trabajó junto a David Barlow, editando uno de los libros pioneros del campo: ?Phobia: Psychological and Pharmacological Treatment?. Posteriormente, editó junto a Robert Prien, Ph.D. ?Long-Term Treatments of Anxiety Disorders?, un libro que aún hoy es una referencia obligada a la hora de estudiar la farmacoterapia de los Trastornos de Ansiedad, pionero en el seguimiento de los resultados terapéuticos a largo plazo y la utilización de medicación antidepresiva para el Trastorno de Pánico. El Dr. Mavissakalian ha acompañado a la AATA en sus más de 20 años de trayectoria en el país, brindando distintas conferencias siempre con la mejor disposición y generosidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239282,"idioma_id":5,"titulo":"Diagnóstico molecular de Porphyomonas gingivalis: Estandarización del método","resumen":"El objetivo del presente trabajo fue estandarizar y optimizar la técnica de PCR convencional para detección de Porphyromonas gingivalis ATCC 33277. Material y métodos: Las cepa de P. gingivalis ATCC33227 se sembró en agar Bruella enriquecido con sangre de carnero, suplementado con hemina y Vitamina K. El ADN se extrajo empleando el protocolo que emplea Bromuro de cetil trimetilamonio (CTAB) .Se evaluó la cantidad y calidad del material genético obtenido con el fotómetro UV Ampli-Quat, AQ-07 Nucleic Acid.  Se realizó la PCR convencional con diferentes concentraciones de MgCl2 1 mM, 1,5 mM y 2.0 mM y a dos temperaturas de alineamiento: 60 °C y 55 °C. Los productos PCR se separaron por electroforesis en un gel de agarosa 1 % Las bandas se visualizaron en un fotodocumentador. La sensibilidad se calculó teniendo en cuenta el número de bacterias en diferentes diluciones. Resultados: Se obtuvo una concentración 1,55x106 ng\/ul de DNA genómico a partir de una suspensión bacteriana de 108 células bacterianas\/ml, con índice de pureza 1,648   (relación de OD260\/OD280). Los mejores resultados se obtuvieron con una concentración de 2 mM de MgCl2 y una temperatura de alineación de 55°C. En cuanto a la sensibilidad se obtuvo un límite de detección de 5 x 10 \/ 5 µL células bacterianas en suspensión. Conclusión. En la prueba de PCR convencional para Porphyromonas gingivalis ATCC 33277, las condiciones óptimas de estandarizacion son la concentración de 2 mM de MgCl y temperatura de alineación 55°C y es necesario una carga bacteriana mínima de 5 x 10 células\/5 ul como límite de detección.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239283,"idioma_id":4,"titulo":"The effect of substrate\/inoculum ratio on the kinetics of methane production in swine wastewater anaerobic digestion","resumen":"by using sewage sludge as inoculum in three substrateto inoculum ratios (SIRs) named A (1:1), B (3:1) and C(6:1), with the objective to identify the proportion that optimizesthe performance of the process. Duplicated batch bioreactorsof 1 L capacity under mesophilic conditions wereused to carry out the experiment. The highest biogas yieldwas observed in A treatment (554 ± 75 mL\/g volatile solid(VS)). Cumulative methane production decreased from382 ± 22 to 232 ± 5 mL\/g VS when SIR increased from 1:1to 6:1. The first-order model and the modified Gompertzequation were used to model the experimental cumulativemethane yield giving adjustments with coefficients of determinationof 96 and 99% respectively. The effect of the SIRwas analysed based on the kinetic parameters of the Gompertzequation, which are methane production potential, maximummethane production rate and lag-phase time. The best performancein terms of the kinetic parameters was obtained fortreatment A; however, treatment B could still ensure a stableprocess. The use of higher inoculum concentration generated463.1% higher methane production rate and required 77.3%shorter adaptation time (lag phase) in the SIR range studied.When higher SIR was used (e.g. 14:1, previous work), it couldbe observed that the Gompertz equation also adjusted adequatelythe experimental data (R2 > 0.99) although the lagphasetime did not remain in a linear relationship with SIR butexponentially above SIR = 6:1. These results demonstratedthat when a low amount of inoculum was used, the adaptationtime of microorganisms resulted much higher than expecteddelaying the methane production and extending the time neededto achieve adequate performance of the process.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239284,"idioma_id":5,"titulo":"Características Epidemiológicas del Tabaquismo en la Población estable de la Ciudad de Cipolletti, 2013-2014","resumen":"RESUMEN. INTRODUCCIÓN: El tabaquismo es la principal causade muerte evitable en el mundo. En Argentina, el tabaco explicaunas 40 000 muertes anuales, en su mayoría por enfermedadescardiovasculares, respiratorias y cáncer. La primera acción quepropone la Organización Mundial de la Salud es el monitoreo, conel fin de obtener la información necesaria sobre la evolución de estaepidemia. OBJETIVOS: Conocer las características relacionadas conel hábito de fumar en la población estable de la ciudad de Cipolletti.MÉTODOS: Se realizó un estudio de corte transversal mediante unaencuesta validada previamente. La población estuvo compuesta pormayores de 18 años con más de 10 años de residencia en la ciudad deCipolletti. Se relevaron indicadores como: fumador actual, exposiciónal humo de tabaco ajeno, edad de comienzo del hábito y relacióncon otros factores de riesgo. RESULTADOS: El 57,2% (IC95%: 54,3-60,1%) reconoció haber fumado alguna vez, y el 20,2% (IC95%:17-23,9%) fumaba tabaco en el momento de la encuesta: 22,9%(IC95%: 18,9-27,3%) entre los hombres y 18,4% (IC95%: 15,5-21,8%) entre las mujeres. La edad promedio de comienzo del hábitofue 17,8±7,8 años. CONCLUSIONES: Se observó una diferenciasignificativa de fumadores actuales frente a los reportes históricostanto nacionales como regionales y provinciales. Este estudio aportavaliosa información para diseñar acciones de intervención en lapoblación de la ciudad y probablemente de la región.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239285,"idioma_id":5,"titulo":"ENSEÑANZA DE LA FISIOPATOLOGÍA A GRUPOS MASIVOS DE ESTUDIANTES DE MEDICINA MEDIANTE EL APRENDIZAJE BASADO EN CASOS","resumen":"Introducción. La enseñanza basada en casos es una metodología centrada en el alumno. El ingresomasivo en las universidades públicas plantea el desafío permanente de la adaptación para mantenerestos espacios de formación. El objetivo del presente trabajo fue evaluar la adaptación del métodopara grupos masivos de estudiantes y compararlo con la modalidad tradicional desarrollada en nuestraasignatura. Materiales y métodos. Se realizó un estudio de cohorte. El grupo 1 estuvo integradopor estudiantes del año 2014 y el grupo 2, por aquellos inscriptos en 2015. Se tomaron característicasbasales de ambos grupos como la situación académica al inicio de la cursada, la relación de aquellacon la evolución durante la cursada y las calificaciones de las evaluaciones parciales. Resultados. Lamedia de la calificación numérica del primer examen parcial de 2014 y el segundo del año no mostródiferencias estadísticamente significativas (p = 0,42). Tampoco se observaron diferencias relevantesen los datos de la cohorte de 2015 (p = 0,20). La comparación de la media de la calificación numéricade todas las evaluaciones parciales de la cohorte de 2014 y la media de la de 2015 arrojó una diferenciasignificativa en favor de la cohorte de 2014 (p <0,01). Conclusión. Los resultados no mostrarondiferencias significativas en el porcentaje de estudiantes que aprobaron la cursada, así como tampocofue superior el rendimiento de la calificación numérica en el promedio de los exámenes parciales en lacohorte de 2015, que fue aquella con la que se implementó la modificación","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239286,"idioma_id":4,"titulo":"Acculturative Stress and Mental Health among Economically Disadvantaged Latinos in Primary Care: The Role of Anxiety Sensitivity","resumen":"Background: The present study examined the role of anxiety sensitivity (AS) in the relation between acculturative stress and mood and anxiety symptoms and disorders among Latinos seeking health services at a primary healthcare facility. Participants included 142 adult Latinos (86.6% female, Mage = 39.05 years, SD = 12.46, and 96.3% reported Spanish as their first language). Results indicated that acculturative stress was indirectly related to the number of mood and anxiety disorders, anxious arousal, social anxiety, and depressive symptoms through AS. The observed effects were evident above and beyond the variance accounted for by gender, age, marital status, educational status, employment status, years living in the United States, and negative affectivity. Overall, the present findings suggest that there is merit in focusing further scientific attention on the interplay between acculturative stress and AS to better understand and inform interventions to reduce anxiety\/depressive vulnerability among Latinos in primary care.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239287,"idioma_id":4,"titulo":"Anxiety sensitivity and rumination: Transdiagnostic factors involved in the relation between subjective social status and anxiety and depressive symptoms and disorders among economically disadvantaged Latinos in primary care","resumen":"Latinos face striking physical and mental health disparities. One factor associated with such disparities is subjective social status, reflecting subjective ratings of social standing. Yet, there is presently a lack of empirical information about the mechanisms underlying relations between subjective social status and anxiety and depressive symptoms and disorders among Latinos in community medical services that serve as focal catchment areas for assessment and intervention programming. The present investigation examined the unique explanatory roles of two transdiagnostic factors, rumination and anxiety sensitivity, in the relation between subjective social status and depressive, suicidal, social anxiety, and anxious arousal symptoms as well as anxiety\/depressive disorders, among Latinos seeking health services at a primary healthcare facility. Participants included 253 Latino adults with annual incomes of less than $30,000 (M age = 39.1, SD = 11.1). Results indicated that rumination and anxiety sensitivity each significantly (independently) mediated associations between subjective social status and all dependent variables except suicidal symptoms. For suicidal symptoms, only rumination was a mediator. The present findings suggest that rumination and anxiety sensitivity may represent explanatory mechanisms for associations between subjective social status and anxiety and depressive symptoms and disorders among economically disadvantaged Latinos in primary care settings.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239289,"idioma_id":4,"titulo":"Relation between biophysical properties of nanostructures and their toxicity on zebrafish","resumen":"In recent years, the use of commercial nanoparticles in different industry and health fields has increased exponentially. However, the uncontrolled application of nanoparticles might present a potential risk to the environment and health.Toxicity of these nanoparticles is usually evaluated by a fast screening assay in zebrafish (Danio rerio). The use of this vertebrate animal model has grown due to its small size, great adaptability, high fertilization rate and fast external development of transparent embryos. In this review, we describe thetoxicity of different micro- and nanoparticles (carbon nanotubes, dendrimers, emulsions, liposomes, metal nanoparticles, and solid lipid nanoparticles) associated to their biophysical properties using this model. The main biophysical properties studied are size, charge and surface potential due to their impact on the environment and health effects. The review alsodiscusses the correlation of the effects of the different nanoparticles on zebrafish. Special focus is made on morphological abnormalities, altered development and abnormal behavior. The last part of the review debates changes that should be made in future directions in order to improve the use of thezebrafish model to assess nanotoxicity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239297,"idioma_id":4,"titulo":"Effect of inulin on dough and biscuit quality produced from different flours","resumen":"One of the methods of improving the nutritional profile of baked-goods is the incorporation of dietary fibre (DF) to the formulation. However, DF retains more water than wheat flour which, affects dough rheological properties and thus the final product quality. Flour is the main ingredient in biscuits and contributes to the baked texture and shape of biscuits. There are large differences in quality among the flours from wheat cultivars and among non-wheat flours used for biscuit production. In previous works, different dietary fibres were tested and inulin was found to have a positive quality  effect on biscuits made from an all-purpose wheat flour without the need of introducing significant changes in dough properties. To know whether these results are extended to different types of flours that can be used for biscuit production, this paper aimed to analyse the effects of different levels of inulin incorporation on dough and biscuits quality made from three different wheat flours and one triticale flour. Chemical and physic-chemical characterization of the flour samples was performed and compared (moisture, ashes, gluten, solvent retention capacity (SRC) and protein content). Inulin was incorporated to biscuits formulation in two levels: 6 and 12% (wheat replacement). Dough and biscuits quality was measured by spread rate during baking and biscuit factor, texture and surface colour. Inulin incorporation increased dough spreading and biscuit factor and decreased biscuit hardness. The enhancing effect of inulin was observed in all flour. The results confirmed the effect of inulin on biscuits obtained with all flour assayed, despite the differences in flour quality.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239298,"idioma_id":4,"titulo":"Effect of defatted almond flour on cooking, chemical and sensorial properties of gluten-free fresh pasta","resumen":"The aim of this work was to analyse the influence of defatted almond flour on soya bean-based glutenfreepasta. Optimal cooking time of pasta varied between 2.0 and 3.5 min, while cooking loss ranged6.1% and 19.7%. The total protein content of samples varied from 30.4% to 41.0% (dry basis, db) incooked pasta. The total phenols content of cooked samples varied between 1.66 and 2.99 mg ellagic acidequivalent\/g, while the antioxidant activity (DPPH?) ranged between 19.1% and 41.9%. The sensory testshowed no significant differences between the formulated pasta samples among brightness (3.20?3.27),surface appearance (1.14?1.20), hardness (2.14?2.36) and elasticity (1.56?1.71). Pasta developed is aninnovative product that improves nutritional and functional properties of gluten-free pasta compared togluten-free and traditional wheat flour pasta available on market.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239299,"idioma_id":4,"titulo":"Optimization of Sesame Oil Extraction by Screw-Pressing at Low Temperature","resumen":"Box-Behnken designs were used to optimize a process for sesame oil extraction by screw-pressing at low temperature (50&nbsp;&deg;C). Experimental designs included seed moisture content (SMC), pressing speed (PS), and restriction die (RD) as the main processing parameters. Extractions at pilot plant scale showed a peak in oil recovery (OR, 71.1&nbsp;&plusmn;&nbsp;2.80%) at 12.3% SMC, 4&nbsp;mm RD, and 20&nbsp;rpm PS. Theoretical models were scanned against experimental data in order to scale up the proposed oil extraction process to industrial scale. A fitted model for OR showed a maximum predicted value similar to the highest experimental value (74.4&nbsp;&plusmn;&nbsp;1.23%) under the following conditions: 8.03% SMC, 10&nbsp;mm RD, and 20&nbsp;rpm PS. Chemical quality parameters of oils obtained at both pilot and industrial scales were in the ranges stated in Codex (FAO\/WHO) standards for non-refined sesame oil.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239300,"idioma_id":4,"titulo":"Morphometric and cristallinity changes on jicama starch (Pachyrizus erosus) during gelatinization and their relation with in vitro glycemic index","resumen":"The effect of gelatinization on the in vitro glycemic index (GI) of starch obtained from jicama tubers was investigated, and the relationships between the starch crystallinity, granule morphology, and the GI were measured. Samples were prepared by heating an aqueous dispersion of starch (1:3 w\/v) at different baking process temperatures (60, 65, 70, 75, or 80°C). Native starch granules showed spherical and polyhedral shapes, with a morphometric aspect ratio (AR) of 0.89-1.0 and sizes ranging from 3 to 21&#956;m. During the thermal process a change in the AR (0.21-0.88) and size (3.0-46&#956;m) was observed, as well as the formation of agglomerates. Native jicama starch exhibited a CA-type X-ray diffraction pattern, while those thermally treated showed a transition from the CA-type to CB-type, decreasing their crystallinity (20.8-11.5%) at higher temperatures. The gelatinization degree of the starch samples and the glycemic index showed the largest values (97.4% and 98.6% respectively) at the highest temperature (80°C), while the crystallinity percentage followed an inverse correlation to temperature (11.5%, 80°C), indicating that the thermal history affected the behavior of the starch enzymatic digestion. The in vitro glycemic index correlated positively with the gelatinization degree based on aspect ratio (R2=0.977), DSC gelatinization enthalpy (R2=0.969), and crystallinity (R2=-0.988). Based on these results a mathematical model is proposed to determine the glycemic index as a function of the aspect ratio. However, more studies are required to validate this information.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239301,"idioma_id":4,"titulo":"Effect of Ingredients on the Quality of Gluten-Free Sorghum Pasta","resumen":"Sorghum is an underutilized cereal in human food production, despite its flour being a potential gluten-free (GF) source in the development of several foods. Thus, the aim of the present investigation was to evaluate the effects and interactions of different ingredients on cooking quality and texture of GF pasta. Egg albumen (A), egg powder (E), xanthan gum (X), and pregelatinized corn starch (P) were used as ingredients, and Box-Behnken experimental design was applied to study the effects of these ingredients on pasta cooking behavior, color, and texture attributes. Responses were fitted to a second order polynomial equation, and multivariable optimization was performed using maximization of general desirability. Next, optimal formulations were validated, compared with two commercial gluten-free pastas by sensory evaluation, and finally, an industrial assay was carried out. Regression coefficients indicated that A and P improved cooking properties while A and E contributed the most to improving the pasta textural properties. As, X and P effects varied depending on the kind of sorghum flour used, the optimal formulations levels were different, but in both cases these models were satisfactory and capable of predicting responses. The industrial assay was carried out with white sorghum flour because it showed a higher acceptability in the sensory evaluation than brown sorghum flour pasta. This industrially made pasta resulted in slightly better cooking properties than the laboratory produced one, with the formulation adapting well to the conventional wheat pasta industrial process. Gluten-free sorghum pasta was produced, showing good cooking and textural properties and being a suitable option for gluten-sensitive individuals.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239302,"idioma_id":4,"titulo":"Relationships between structural fat properties with sensory, physical and textural attributes of yeast-leavened laminated salty baked product","resumen":"The aim of this study was to establish relationships between structural fat properties and sensory, physical and textural attributes of yeast-leavened laminated salty products. Refined bovine fat (MG1) and shortening (MG2), with a solid fat content (SFC) higher than 20% at temperature range of 15?35 °C were more viscous and less sensitive to temperature changes. The micrographs of dough|fat|dough sections corresponding to samples with MG1 and MG2 revealed a lower penetration of the fat sheet in the dough section due to the more entangled fat structures that did not allow a great flow throughout the dough layer. Consequently, the structure of laminated dough pieces made the systems highly resistant to deformation. The laminated dough pieces elaborated with these fats showed the highest increments in their height and maintained symmetry. Products with fat with least SFC and higher destructuration rate produced smoother laminated structures due to the presence of pores. While products with MG1 and MG2 showed tortuous images and complex structures, associated to layers and extended pores. MG1 and MG2 products were preferred (flavor and appearance) over those with MG3. The highest ranking samples in the acceptability analysis were symmetric, presented very flaky crusts and had a high level of lamination.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239303,"idioma_id":4,"titulo":"Physical characterization and fluidization design parameters of wheat germ","resumen":"DOI : 10.1016\/j.jfoodeng.2017.05.011Wheat germ is the embryo of de wheat seed, it contains a high tocopherol and protein content, and high quality proteins and fatty acids. Also, wheat germ has a considerable enzymatic activity that limits its shelf life. The aims of the study were to physically and sorptionally characterize wheat germ particles, select the more convenient model to describe the relationship between moisture content and water activity of wheat germ and to determine their design parameters of thermal fluidization process with air. The principal axes of the particle were measured by image analysis, and their dimensions and geometric parameters were calculated. Four isotherm models were fitted to experimental data. GAB model was the more accurate to explain the experimental data. The fixed bed density and the void fraction were measured. The fluid-dynamic studies permitted to determine laminar (277.46±17.48) and turbulent (7.79±0.69) coefficients of the Ergun equation and the minimum fluidization velocity (0.35±0.02 m\/s).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239304,"idioma_id":4,"titulo":"Wheat germ stabilization by infrared radiation","resumen":"Wheat germ has an important enzymatic activity, being lipases the enzymes which cause the highest impact in the reduction of shelf life. The objective of this study was to evaluate the effects of infrared radiation on wheat germ stabilization in an attempt to extend the shelf life. The effects of treatment time, gap (sample distance to IR emitters) and infrared radiation intensity on wheat germ were analyzed through response surface methodology. Final moisture content, final temperature, color of germ and germ oil quality parameters: free fatty acid content changes and total tocopherol content were the responses evaluated using a Box-Behnken design. A combination of an infrared radiation intensity of 4800 W\/m2, a 3 min treatment and 0.2 m emitter-sample distance were the best processing condition to stabilize the wheat germ without significantly reduction of the tocopherol content. A confirmatory experiment was conducted with these optimal conditions, and the heat-treated and raw germ samples were stored for 90 days at room temperature in three layer packages to protect them against light and oxygen. The oil quality parameters indicated that the raw germ had a shelf-life of about 15 days, with the heat-treated wheat germ maintaining its quality for at least 90 days under these stored conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239305,"idioma_id":4,"titulo":"Chia (Salvia hispanica L.) oil stability: Study of the effect of natural antioxidants","resumen":"The chia seed (Salvia hispanica L.) is globally popular and valued for its nutritional and health attributes. Chia oil is mainly composed of triglycerides, in which polyunsaturated fatty acids (PUFAs, linoleic and &#945;-linolenic acids) are found in high amounts. Although it seems evident that such fatty acid composition is favorable from a nutritional point of view, a higher content of linoleic and linolenic acids results in poorer oxidative stability and shorter shelf life of the oil. The aim of this study was to evaluate the combined effects of the storage condition (300 days under fluorescent light - 800 Lux - or in the dark, both at room temperature) with the addition of natural antioxidants (rosemary extract, RE; tocopherol, TOC; ascorbyl palmitate, AP). In the dark, the combined addition of AP and TOC significantly reduced lipid oxidation and improved oil shelf life. Moreover, this combination maintained an acceptable quality of at least up to 300 storage days. Results from this work highlight the influence of illumination condition on chia oil oxidative stability, suggesting that this oil should be stored in containers with light-barrier properties, and probably added to the antioxidants examined in the current study.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239309,"idioma_id":5,"titulo":"METODOLOGÍA PARA EVALUAR EL RENDIMIENTO ACADÉMICO DE EN UNA CÁTEDRA","resumen":"RESUMEN:El presente estudio, tiene por objetivo: ?Proponer una metodología de evaluación del Rendimiento Académico de una Cátedra a fin de tener un diagnóstico de la misma?.El Rendimiento Académico de una cátedra es el indicador que está constituido por tres  dimensiones: rendimiento, eficiencia y desgranamiento. Las cuales tienen las siguientes características: a)Dimensión Rendimiento, donde consideramos las notas obtenidas en los exámenes; b) Dimensión Eficiencia, donde contemplamos la forma en que los estudiantes aprueban la materia, c) Dimensión temporal, donde analizamos la continuidad o discontinuidad de los estudiantes en el ritmo temporal relativo al año académico. Realizamos el diagnóstico de la cátedra de Matemática II, de la Facultad de Bioquímica, Química y Farmacia de la UNT.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239320,"idioma_id":5,"titulo":"Tirar (o no tirar) a los viejos por la ventana. La dinámica generacional en la Juventud Sindical en Argentina a partir de un estudio de caso (2010-2015)","resumen":"El regreso de los sectores tradicionales de la clase obrera como actores centrales de la política en Argentina desde el año 2003, se produjo de forma paralela al resurgimiento de determinadas formas de participación política juvenil. El campo de estudios en juventud y política muestra que a partir de la presidencia de Néstor Kirchner se observa una paulatina pero fuerte reactivación del protagonismo juvenil que a diferencia de la década anterior se produjo por vías tradicionales de implicación política y pública (Vázquez y Vommaro, 2008), como son los partidos políticos y los sindicatos. Siguiendo a Vázquez (2013), estas formas de participación juvenil conllevaron un proceso de proliferación y revitalización de colectivos que se autodefinen y reivindican como juveniles. En el campo sindical, más específicamente dentro del sindicalismo de tradición peronista, dicho proceso tuvo su expresión en la creación de las juventudes sindicales conformadas como espacios organizativos al interior del ?kirchnerismo?  para la participación de los jóvenes trabajadores . El objetivo del artículo es analizar las relaciones generacionales que se producen entre los jóvenes trabajadores y los ?viejos? dirigentes sindicales a partir de la emergencia de la JS en la región del Gran La Plata. Más específicamente, indagaremos en los sentidos atribuidos a ?la juventud? por parte de ambos y cómo se percibe e identifica a los ?viejos? dirigentes. Los interrogantes que guían el artículo son los siguientes. Por un lado, ¿cuáles son los sentidos que adquiere la categoría ?juventud? para los jóvenes? ¿Cómo interpelan y ubican estos a los dirigentes? Y, por otro, ¿cómo los dirigentes interpelan a los jóvenes y en qué lugar se ubican ellos mismos? Por último, ¿cuáles son las tensiones que se producen entre las dos generaciones de sindicalistas y qué elementos se ponen juego?","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239321,"idioma_id":5,"titulo":"Entre caras y caretas. Caricatura y fotografía en los inicios de la prensa ilustrada argentina","resumen":"A pesar de los debates que a partir de 1839 enfrentaron al daguerrotipo con las artes tradicionales, fotografía y caricatura iniciaron tempranamente una fructífera relación, que se extendería al nuevo siglo. En este artículo estudiamos algunas particularidades de este fenómeno en la prensa argentina, focalizándonos en la revista Caras y Caretas, cuyo carácter pionero y modélico sentó las bases para muchas publicaciones locales posteriores. Analizando las diversas formas de interacción entre fotografía y caricatura, mostramos el rápido proceso de sofisticación y entrenamiento visual que propiciaron estas tempranas revistas ilustradas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239324,"idioma_id":5,"titulo":"¿Las TIC incluyen? Aulas virtuales para estudiantes, primera generación de universitarios en la UNPAZ","resumen":"La ponencia tiene  por  finalidad  dar  a  conocer  y  reflexionar  acerca  de  la  modalidad  de  incorporación de Tecnologías de la Información  y  la  Comunicación  (TIC),  en  la  Universidad  Nacional  de  José  Clemente  Paz  (UNPAZ), una de las universidades llamadas ?del Bicentenario?, ubicada en el segundo cordón del Conurbano Bonaerense, cuyo lema es Inclusión con calidad académica.Esta declaración de principios interpela a to-dos  los  actores  de  la  institución  y,  al  equipo  de  Formación  Virtual  en  particular,  lo  convierte en responsable de otra inclusión, la de las TIC en las actividades académicas. Esa exigencia  va  acompañada  en  forma  necesaria,  de al menos, una doble reflexión: una refiere a definir de qué inclusión hablamos, es decir, ¿digital?, ¿educativa?, ¿de uso de herramientas  informáticas?  Mientras  que  la  segunda  remite a cuáles son las características a tener presente  en  el  momento  de  tomar  decisiones que afectarán las formas de enseñar y de aprender,  las  prácticas  educativas  y  los  modos de comunicación si se utilizan las TIC. En definitiva, ¿permiten hacer efectiva la inserción  con  calidad  académica?  Intentaremos  acercar  algunas  respuestas  que  habiliten nuevas preguntas","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239326,"idioma_id":5,"titulo":"Integración pedagógica y laboral: Pensar en un cambio cultural y las transformaciones sociales desde una Escuela Especial","resumen":"Las representaciones que se tienen de las personas con discapacidad y su educación, transitan por diferentes momentos en la historia. Pasan de ser considerado un ser poseído por el demonio a estar ocultado, ser un lunático que debe ser curado, hasta posturas que sostienen la necesidad que sea institucionalizado. Así hasta arribar en el siglo XX donde se piensa que puede ser educado. En este nuevo contexto se postula una visión centrada en la educación y en sus posibilidades. De esta manera y progresivamente, se crean escuelas especiales para su atención educativa. La decisión Estatal en este sentido, establece que estas organizaciones se organicen según tipologías de discapacidad. La formación que orienta a los docentes, implica también este paradigma. En el presente escrito se centra en una Escuela Especial que atiende a jóvenes con discapacidad intelectual con finalidades de orientación laboral. De este el establecimiento educativo integra dos aspectos de la persona discapacitada: lo pedagógico y lo laboral.Históricamente y cuando la escuela especial se propone la integración escolar como un paso más en la educación, lo hacen tendiendo bajo el criterio de normalización de la persona con discapacidad en la sociedad. En esta toma de posición se requiere de una serie de decisiones políticas, educativas y de instrumentos legales para que este proceso se lleve a cabo en forma concreta.Dentro de este contexto de desempeño educativo, donde se integra la educación pedagógica y laboral y la integración con criterio de normalización, se postulan algunos interrogantes ¿qué posturas, visiones e ideología hacen posible trabajar con las personas con discapacidad? En un contexto de contracción de la economía y de una estructuración económica laboral de tipo capitalista, ¿cuál es la posibilidad real y factible para la inserción laboral de las personas con discapacidad?El presente trabajo tiene como propósito brindar herramientas de reflexión y discusión en relación a estas y otras preguntas y en este recorrido aportar a la construcción de miradas en relación con la integración al mundo pedagógico y laboral de las personas con discapacidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239327,"idioma_id":5,"titulo":"Propiedad, apropiación y robo en torno a la autoría","resumen":"El tema de la autoría no solamente plantea temas éticos y legales, también afecta de modo muy determinante las prácticas de docencia e investigación. Este trabajo trata de analizar la relación entre los conceptos de autoría, de propiedad, de lo propio ?que es parecido pero no es lo mismo? y de las diferentes formas de ?robo?, legal e ilegal que se perpetran en torno a la producción intelectual en el campo de las ciencias sociales y de las humanidades. Indaga sobre el modo en que ciertas tradiciones operan reproduciendo prácticas instituidas a nivel educativo y de la producción de conocimiento de modo asimétrico entre instituciones y docentes e investigadores, quienes suponen sustraerse de las relaciones de producción y las formas de dominio establecidas y sin embargo son atravesados por ellas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239329,"idioma_id":5,"titulo":"200 años de país federal y derecho unitario  (Positivismo jurídico extremo)","resumen":"La República Argentina ha arribado a los 200 años como país independiente, siendo su sistema jurídico una consecuencia de su historia. El Federalismo es el sistema político que se impuso y que teóricamente debería gobernar el derecho. No siempre es el caso. Luego de 200 años, se ha progresado poco en ese reconocimiento por ello la reforma del CCyC ha dado la oportunidad de reabrir el debate y poder analizar los alcances del nuevo escenario. El ISSN es 0329-9430","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239330,"idioma_id":5,"titulo":"Políticas de egreso: hacia el rol tutorial del docente universitario","resumen":"Desde su creación, la UNLa ha ido desplegando distintas estrategias de acompañamiento y cuidado de sus estudiantes. Dichas estrategias abarcan desde el pre-ingreso e ingreso, con los talleres de orientación vocacional, con las tutorías y talleres de lectura y escritura de textos académicos, con la tarea de los Docentes Orientadores) hasta el egreso (con las tutoría disciplinares\/metodológicas y de escritura de Trabajos Finales), con sus infinitos y diversos puntos intermedios. Concretamente, en la actualidad, podríamos mencionar ocho espacios de tutorías. A saber: los Docentes orientadores, Estudiantes Tutores Pares; las Tutoría de lectura y escritura de textos académicos,  la Tutoría y el taller de matemática, la Tutoría de exámenes libres para Idiomas e Informática: Tutorías de Trabajo final y las Tutorías de apoyo a becarios","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239332,"idioma_id":5,"titulo":"DETERMINACIÓN DE LAS CONSTANTES HÍDRICAS DE JUJUY Y SALTA A NIVEL DE ASOCIACIÓN, PARA EL MONITOREO DEL AGUA EN EL SUELO","resumen":"Unas de las principales causas de la variación de los rendimientos de los cultivos, es la disponibilidad de agua en el suelo. A pesar de la importancia de la humedad del suelo para la estimación de los rendimientos de los cultivos, la determinación fiable de esta variable a escala regional, a través de mediciones puntuales convencionales, es compleja. La información requerida por los modelos de balance hídrico es variable y depende de su complejidad. Entre la información necesaria para la modelización del agua en el suelo, están las precipitaciones, la evapotranspiración y las constantes hidrológicas. La primera se la obtiene por mediciones de diferentes lugares, la segunda por estimaciones, mientras que al no disponer de mediciones de humedad del suelo in situ, las constantes hidrológicas del suelo se estiman a partir de datos de sus propiedades físicas. El objetivo del presente trabajo es estimar las constantes hidrológicas del suelo, correspondiente a las asociaciones de suelos para las provincias de Jujuy y Salta. Las constantes hídricas estimadas a nivel de asociación, expresan la gran variación edáfica que presentan los suelos en ambas provincias a las diferentes profundidades estudiadas (30, 70, 100 cm y profundidad efectiva).Palabras claves: Noroeste Argentino, Asociaciones, constantes hídricas","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239334,"idioma_id":5,"titulo":"Influencia del estrés calórico sobre los glóbulos blancos en vacas Holando Argentino","resumen":"La combinación de altas temperaturas y humedad, características de la provincia de Santa Fe, principal zona de producción lechera de Argentina, afectan la producción láctea. El índice de temperatura y humedad (ITH) puede ser utilizado como un indicador de estrés térmico. El objetivo de esta investigación fue evaluar los efectos del estrés calórico sobre los glóbulos blancos en respuesta a la liberación de cortisol en bovinos productores de leche. El estudio se realizó en el Módulo Tambo de la Facultad de Ciencias Agrarias, situado en Zavalla (33°1&#8242;S, 60°53&#8242;O), Santa Fe, Argentina, durante el período 2013-2014. Se utilizaron 30 vacas Holando Argentino, del rodeo de vacas en ordeñe de segunda y tercera lactancia. Las muestras fueron tomadas en primavera (ausencia de olasde calor) y verano (presencia de olas de calor), durante el ordeño de la mañana y de la tarde. Se utilizó un método de radioinmunoanálisis para dosar cortisol, (Kit comercial Coat-A-Count Cortisol); un contador hematológico, MINDRAY-BC 2800, para determinar la cantidad total de glóbulos blancos, y la coloración de May Grünwald y Giemsa para determinar la cantidad de neutrófilos y linfocitos. Se observó aumento del ITH en las tardes de verano, coincidiendo con un aumento significativo de cortisol, una disminución relativa del número de linfocitosy un aumento del número de neutrófilos. La relación Neutrófilos\/Linfocitos también fue mayor en verano. Se concluye que el estrés calórico, medido a través del ITH, modifica el número y la proporción de glóbulos blancos,y esto podría atribuirse al aumento del cortisol plasmático.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239335,"idioma_id":4,"titulo":"Din&aacute;mica espacial del proceso de extranjerizaci&oacute;n de la tierra en la Patagonia","resumen":"En las últimas dos décadas se produjo en la Patagonia argentina un fuerte proceso de compra de tierras por parte de inversores extranjeros, situación que ha debido ser regulada a través de nuevas normativas legales de nivel nacional y provincial. Las compras de tierras han seguido un patrón espacial de acuerdo con la lógica de uso que los nuevos inversores han planteado, ya sea para la realización de actividades ganaderas tradicionales, para la realización de actividades mineras, o para nuevos emprendimientos turísticos, sólo en casos donde el uso futuro de las tierras no ha sido muy claro por parte de los nuevos inversores, el patrón espacial es muy incierto y fragmentario. No obstante, más allá de estas lógicas espaciales, los procesos de cambio muestran un proceso de concentración en la propiedad de las tierras en manos de estos inversores externos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239339,"idioma_id":5,"titulo":"Una mirada hacia el canon literario del Siglo XIX en la Nueva Escuela Secundaria","resumen":"El artículo plantea una reflexión sobre el canon de la literatura argentina, que se inicia en la Historia de la literatura argentina de Ricardo Rojas, compilación ambiciosa que ha gozado de reconocimiento y aceptación por parte de la crítica. Nos preguntamos si este canon aún prevalece en nuestro tiempo y cómo se refleja, de ser así, en las propuestas de enseñanza de la literatura argentina en la Nueva Escuela Secundaria. El propósito es examinar la presencia o la ausencia de tal canon en las instituciones educativas de la ciudad de San Fernando del Valle de Catamarca. En una primera parte, reflexionamos acerca del concepto de canon literario. Luego, analizamos los documentos curriculares vigentes en la búsqueda de respuestas a las preguntas iniciales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239341,"idioma_id":4,"titulo":"Optimization of the design, operating conditions, and coupling configuration of combined cycle power plants and CO 2 capture processes by minimizing the mitigation cost","resumen":"This paper deals with the optimization of the coupling between a natural gas combined cycle (NGCC) plant and a post-combustion CO2 capture process by minimizing the mitigation cost &#8722; defined as the ratio between the cost of electric power generation and the amount of CO2 emitted per unit of total net electric power generated &#8722; while satisfying the design specifications: electric power generation capacity and CO2 capture level. Three candidate coupling configurations, which differ in the place where the steam is extracted from, are optimized using detailed and rigorous models for both the NGCC and the CO2 capture plants. By comparing the mitigation cost of each configuration, the optimal integration configuration and the corresponding optimal sizes and operating conditions of all process units (steam turbines, gas turbines, heat recovery steam generators HRSGs, absorption and regeneration columns, reboilers and condensers, and pumps) are provided. In the computed optimal solution, the steam required by the CO2 capture plant is extracted from both the steam turbine and the HRSG (evaporator operating at low pressure), and the mitigation cost is 90.88 $\/t CO2. The optimal solution is compared with suboptimal solutions corresponding to the other two candidate coupling schemes. These solutions are compared in detail regarding capital investment and operating costs, HRSG configuration, process unit sizes, and operating conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239342,"idioma_id":4,"titulo":"Speech transmission index variation doe to ventilation and air-conditioning system in university classrooms","resumen":"A major factor to be considered in the study of teaching-learning process based on spoken communication is sound field. Excessive background noise levels or reverberation time values inside a classroom interfere with oral communication, creating an acoustic barrier to the teaching-learning process. In previous work, reverberation time was measured in a sample of university classrooms in the City of Córdoba, observing that such parameter has tripled the value recommended by international literature. Furthermore, background noise level was measured in two different conditions: heating, ventilating and air-conditioning system turned on and off. Then, these levels were evaluated according to NC and RC criteria established by IRAM 4070, where more than 50 % of the population under study complied with the NC criteria, and none with the RC criteria. In this paper, results of speech transmission index (STI) measurements for both conditions of heating, ventilating and air-conditioning system are presented. Results of STI and signal-to-noise ratio obtained in both conditions are compared. Variations of up to twelve times the just-noticeable difference of STI were found.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239345,"idioma_id":4,"titulo":"Measurement of insertion loss of ear-muff type protectors using the impulse response technique","resumen":"The essential requirements that hearing protectors need to fulfill as personal protective equipment are evaluated in Argentina through a series of IRAM (Instituto Argentino de Normalización y Certificación) standards. In particular, IRAM 4060-3 (equivalent to ISO 4869-3:2007) standard specifies a simplified method for the measurement of insertion loss (IL) of ear-muff type protectors. This method can be used to test occasional performance differences on manufacturing, as part of type approval or certification procedures, and to investigate performance variations due to product aging. The IL of a hearing protector is commonly obtained using systems based on broadband pink noise (BPN) signals. This paper analyzes and compares the IL of eight different hearing protectors obtained with this technique and with an impulse response measurement based system. The results show that both techniques present similar IL values, within the dispersion range expected for this test. Also, the impulse response system reduces the test execution time, and proved to be robust, reliable and economical.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239347,"idioma_id":4,"titulo":"SAMSoft: acoustical devices automatic measurement system software","resumen":"A common way to experimentally characterize a linear time-invariant acoustic system is by measuring its impulse response for each location of interest. Currently several methods exist for such purpose, being signal deconvolution the one which exhibits better performance. Moreover, measurement systems are usually aimed to particular applications, working with expensive platforms and proprietary software. In this paper design and development of specific software called SAMSoft, which manages an automatic measurement system for acoustic devices, are described. SAMSoft presents a modular, scalable and easy to upgrade design developed in Matlab, based on the model-view-control system pattern which enables source code reuse and simple functionality expansion. Application allows impulse response measurement with different excitation signals, time windows introduction to obtained measurements, time and frequency domain visualization, and spectral analysis in octave and one-third octave bands. It runs on a hardware based on a control unit and a mobile platform, being capable of measuring 360º in the horizontal plane with an angular resolution of up to 0.06º. Impulse response of different acoustic transducers measured showed a signal noise ratio of up to 40 dB in frequency bands under 100 Hz. In power measurements for octave and one-third octave bands a maximum error of 0.12 dB was obtained.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239348,"idioma_id":4,"titulo":"Review of the Eriococcidae (Hemiptera: Coccomorpha) infesting Fabaceae in Argentina, with descriptions of three new species of Acanthococcus Signoret","resumen":"Three new species of Eriococcidae from Argentina, namely Acanthococcus haywardi Juárez & González sp. nov., A.punctatae Juárez & González sp. nov. and A. riojensis Juárez & González sp. nov., are described and illustrated, bringingthe total number of eriococcid species now known from Argentina to 12, of which six belong to Acanthococcus Signoret and six to Hempelicoccus Kozár. They are found on 11 species of Fabaceae (subfamilies Mimosoideae and Caesalpinioidae),are widely distributed and are all restricted to the Neotropical region and the South American Transitional Zone. A key to the 12 Eriococcidae species now known on Fabaceae in Argentina is included.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239350,"idioma_id":5,"titulo":"De las violencias del saber a las dialógicas del reconocimiento. Múltiples apelaciones y experiencias en la investigación colaborativa con la comunidad sorda argentina","resumen":"María Eugenia Almeida y María Alfonsina Angelino plantean la experiencia que se está llevando adelante entre la comunidad sorda y tres universidades nacionales de Argentina a través del proyecto ?Caleidoscopios del reconocimiento. Historias de la comunidad sorda argentina en clave cartográfica?. El mismo, referenciado como marco de una ?investigación etnográfica colaborativa e intercultural?, apunta a la construcción de prácticas de investigación y la formación de investigadores\/as sordos\/as. Los planteos que allí se vierten sobre las violencias del saber, constituyen una bienvenida interpelación respecto al investigar y su potencial papel político. El tema del reconocimiento de la comunidad se vuelve materialidad en este proyecto en el vaivén que se genera en la potencialidad de investigar y ser investigado, de producir conocimiento colectivo y hacer visible una temática de la cual se cree se conoce más de lo que de hecho se conoce. Históricas han sido las luchas de la comunidad sorda en la mayoría de los países occidentales, planteando su resistencia a ser incluidos dentro de la población en situación de discapacidad por señalar que el problema de base es comunicacional y, por ende, entre las distintas partes que intentan dar significado al mensaje. Sin embargo, el modelo biologicista oralista -enmarcado en la ideología de la normalidad- ha calado tan hondamente en estas sociedades, que ha colocado únicamente la responsabilidad en uno de los pares de la dupla emisor-receptor, catalogado como deficitario. A través de la experiencia presentada, puede advertirse cómo a través de la investigación etnográfica participativa, se recuperan los aspectos sustanciales del ser sordo, de la comunidad sorda argentina, de su identidad como colectivo minoritario pero también de su identidad nacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239351,"idioma_id":5,"titulo":"Consumo de alimentos fuente de micronutrientes en la población argentina: adecuación a las recomendaciones de las nuevas guías alimentarias","resumen":"Introducción: El consumo de alimentos fuente de micronutrientes asegura niveles adecuados de ingesta y a la vez patrones alimentarios de buena calidad nutricional se asocian con menor riesgo de desarrollar enfermedades crónicas. El propósito de este estudio es describir la frecuencia de consumo de alimentos de alta densidad de nutrientes, su adecuación a las recomendaciones de guías alimentarias y la identificación de los nutrientes de mayor riesgo de inadecuación. Materiales y Método: Se realizó una encuesta de frecuencia de consumo de 34 alimentos seleccionados a una muestra nacional de 1000 sujetos entre 18 y 70 años de edad, de ambos sexos y diferentes niveles socioeconómicos. Sobre una plataforma digital, online y a través de un cuestionario semiestructurado que contempló estímulos visuales (fotos) de diferentes tamaños de porciones de alimentos. La encuesta se realizó en diciembre de 2015. Los consumos reportados se compararon con las recomendaciones de las guías alimentarias vigentes para nuestro país. Resultados: Más de la mitad de la muestra refiere consumos poco frecuentes (3 veces o menos\/semana o nunca) de algunos alimentos y grupos de alta densidad de nutrientes. La menor frecuencia de consumo diario se observa en cereales integrales. Solo el 17% de los sujetos encuestados logra cubrir de manera simultánea tres o más de los cinco grupos alimentarios encuestados. Mientras que, 22% no logra cubrir adecuadamente ninguno. Considerando una pauta intermedia de consumo sugerido, el porcentaje que cubre 3 o más grupos asciende a 34,5%. El rango de personas cuyos consumos podrían incurrir en un escenario de inadecuación en la ingesta de nutrientes se extiende entre 23% y 67%. Conclusión: El trabajo aporta conclusiones importantes para la comunidad profesional y los actores involucrados en procesos de toma de decisiones. Son necesarias intervenciones que mejoren las brechas significativas entre el consumo de alimentos de alta densidad de nutrientes y su recomendación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239353,"idioma_id":4,"titulo":"Living with electric and magnetic fields (EMF)","resumen":"For nearly 40 years, substantial research budgets have been devoted worldwide to the question of possible health effects of power frequency electric and magnetic fields. Over 400 epidemiological studies have been carried out around the world not only to study cancer but also many other health outcomes. At the same time, thousands of laboratory studies on cells, tissues and whole animals have been carried out. The amount of data generated by this international research effort is exceptional. In general, studies have failed to establish a causal relationship between any particular adverse health outcome and electric or magnetic field exposure. Considering the fact that 50\/60 Hz electric and magnetic fields have been extensively studied worldwide and that no adverse health effect has been clearly identified, it is reasonable to conclude that a causal relationship with any particular disease including childhood leukemia, other cancers, cardiovascular diseases, neurodegenerative disorders and reproductive outcomes is very unlikely. The knowledge gained from this research is very reassuring. Based on currently available scientific evidence, and considering the fact that the levels at which people are exposed are very low, there is no need to apply preventive measures regarding daily exposures to power frequency electric and magnetic fields. Present exposure limits recommended by international organizations offer adequate protection. The International Commission on Non-Ionizing Radiation Protection recommends a limit of 200 &#956;T for the public and 1,000 &#956;T for the workers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239357,"idioma_id":5,"titulo":"Construir y sostener una red físico-virtual de un instituto de investigación: el caso DHD-IRICE","resumen":"El artículo presenta un primer análisis multidimensional del caso de estudio ?DHD-IRICE?, donde se abordó el rediseño organizacional físico-virtual del Instituto Rosario de Investigaciones en Ciencias de la Educación (IRICE) de la Universidad Nacional de Rosario y del Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina). El IRICE buscaba mejorar su visibilidad en la web e iniciar un proceso de transformación de la cultura investigativa, de publicación en Acceso Abierto y de formación de recursos humanos, hacia una modalidad de trabajo colaborativo y en red. Para el estudio del caso se ha aplicado un modelo analítico conformado por cuatro dimensiones integradas: Social, Institucional, Tecnológica y Textual. Se considera factible la ?Sostenibilidad-DHD? cuando se evidencia un proceso de convalidación social, cierta perdurabilidad en el tiempo y un crecimiento de la red socio-técnica inicial. A partir de lo observado es posible afirmar que se ha alcanzado una positiva convalidación social del DHD-IRICE. Sin embargo, es necesario profundizar las estrategias institucionales para favorecer una mayor cohesión en cuanto a la participación y producción en redes colaborativas de investigación y\/o extensión mediatizadas. Esto implica mejorar las condiciones de sostenibilidad en relación a la escalabilidad y perdurabilidad. Así, el involucramiento de distintos grupos sociales y el aumento de la producción de contenido colaborativo impulsarían al IRICE como referente nacional en la investigación educativa.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239359,"idioma_id":5,"titulo":"Herramientas de investigación para incrementar el impacto de la ciencia en la industria química","resumen":"En el trabajo se precisan las posibilidades y necesidades de las diferentes herramientas para investigación científica en la industria química, partiendo de las tradicionalmente utilizadas analogías entre las transferencias de impulso, de calor y de masa, y sus grupos adimensionales y haciendo hincapié en los métodos de planificación estadística de experimento para la búsqueda de las cinéticas de las reacciones y las regiones de comportamiento óptimo y las posibilidades que la modelación matemática brinda para determinar información sobre los fenómenos de transporte reales y las posibilidades de escalados de instalaciones de la industria química. Se refuerza la necesidad de un adecuado respaldo experimental para la propuesta de toma de decisiones y como a través de los modernos métodos cibernéticos se pueden alcanzar más rápidamente respuestas a las demandas de la industria. Se enfatiza el significado formativo que como instrumentos de trabajo para el futuro profesional tiene la incorporación de estos métodos en el trabajo formativo de los estudiantes. Finalmente se elaboran conclusiones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239360,"idioma_id":5,"titulo":"ANSIEDAD LABORAL: SU RELACIÓN CON LA PERSONALIDAD Y SU IMPACTO EN LA POSIBILIDAD DE EJERCER ROLES DE LIDERAZGO","resumen":"El constructo de la ansiedad laboral busca identificar diferencias individuales en el modo en que la ansiedad puede afectar el desempeño en el área del trabajo. El objetivo del presente estudio es investigar su relación con las dimensiones básicas de la personalidad, en particular, su asociación con variables interpersonales (por ej. asumir roles de liderazgo). 204 trabajadores de la Ciudad de Buenos Aires y 74 pacientes de una clínica de Trastornos de Ansiedad de la Ciudad de Buenos Aires (también trabajadores al momento del estudio) completaron el Inventario de Ansiedad en el Ámbito Laboral, y el NEO-FFI. Se recolectó también información acerca de variables relacionadas al trabajo. Se hallaron diferencias estadísticamente significativas en la subescala de Ansiedad Social y Búsqueda de Reaseguros, en particular los sujetos que no tienen gente a cargo puntúan más alto, tanto para la muestra clínica, como no-clínica. En relación a la personalidad de los líderes, bajo Neuroticismo y alta Responsabilidad permitió diferenciar a la población general de la muestra clínica. Adicionalmente, la Extroversión apareció como una dimensión que diferenciaría dentro de la muestra clínica a aquellos con gente a cargo de los que no. Puede concluirse que los trabajadores que  poseen un Perfil Ansioso Social y Buscador de Reaseguros en el Trabajo tienen significativamente menos chances de liderar grupos con las consecuencias que ello pudiera acarrear en su desarrollo profesional\/laboral.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239361,"idioma_id":5,"titulo":"CONSUMO DE LACTEOS Y ADECUACION DEL APORTE DE CALCIO EN ESTUDIANTES DE LA FACULTAD DE MEDICINA DE LA UNNE","resumen":"Los lácteos constituyen un grupo alimentario de gran relevancia para el ser humano, se consideran como tales a la leche y sus derivados, por ser los alimentos fuente de calcio por excelencia su ingesta adecuada garantiza cubrir la Ingesta Recomendada del mineral. El objetivo general del trabajo fue determinar la adecuación de la Ingesta recomendada de calcio, para ello se realizó un estudio de enfoque cuantitativo de carácter descriptivo. La población de estudio fueron los estudiantes de Licenciatura en Enfermería de la Facultad de Medicina de la Universidad de Nacional del Nordeste. Sobre ella se tomó una muestra no probabilística accidental conformada por 100 unidades muestrales. Tras el análisis de datos se observó que el 22% de los encuestados no cubre la IR de calcio mientras que el 58% lo hace en exceso y solo el 20% cumple la media de 1000 mg\/día. Como conclusión se destaca la necesidad de implementar estrategias de educación nutricional a fin de mejorar el patrón de consumo de lácteos y la consecuente ingesta de calcio.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239365,"idioma_id":4,"titulo":"The identity of the Organization in the Face of Change. The Case of Employees of Com.Tu.Lab when They Become Faculty Members at the National University of the Northeast (UNNE), Argentina","resumen":"We analyze processes of identification and symbolic appropriation of the institutional culture in the Labour Relations, Social Communication and Tourism Careers in a state university which until 2008 functioned unified as an institute called Dependent Careers of the Chancellorship. After the mentioned date and until 2013, each was formally transferred - although not geographically - to the Faculties of Economic Sciences, Humanities and Arts Design and Cs. Of Culture respectively, thus in 2012, a General Coordination to contain and manage them is created. Since the carers continue to function in the same space and former employees, the aim of this research is to determine whether the old dominant administrative practices persist or they were modified given the transition to change. The methodology employed consisted in the techniques of semi-structured interviews supported by the participant observance of the employees in their everyday tasks. A loss of the sense of autonomy was detected on them, showing a permanent necessity of building a new identity while living in conflict with the residual. The formality and the hierarchy are part of the university culture. The recommendations would be to plan the on-going formation on the mission, vision and functions of the new public office.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239368,"idioma_id":5,"titulo":"Aplicación del modelo de revaluación de la RT 31. Su incidencia en la medición del patrimonio y los resultados","resumen":".","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239369,"idioma_id":4,"titulo":"Changes in leaf stomatal conductance, petiole hydraulics and vessel morphology in grapevine (Vitis vinifera cv. Chasselas) under different light and irrigation regimes","resumen":"Hydraulic conductance and water transport in plants may be affected by environmental factors, which in turn regulate leaf gas exchange, plant growth and yield. In this study, we assessed the combined effects of radiation and water regimes on leaf stomatal conductance (gs), petiole specific hydraulic conductivity (Kpetiole) and anatomy (vessel number and size); and leaf aquaporin gene expression of field-grown grapevines at the Agroscope Research Station (Leytron, Switzerland). Chasselas vines were subjected to two radiation (sun and shade) levels combined with two water (irrigated and water-stressed) regimes. The sun and shade leaves received &sim;61.2 and 1.48molm-2day-1 of photosynthetically active radiation, respectively, during a clear-sky day. The irrigated vines were watered weekly from bloom to veraison whereas the water-stressed vines did not receive any irrigation during the season. Water stress reduced gs and Kpetiole relative to irrigated vines throughout the season. The petioles from water-stressed vines showed fewer large-sized vessels than those from irrigated vines. The shaded leaves from the irrigated vines exhibited a higher Kpetiole than the sun leaves at the end of the season, which was partially explained by a higher number of vessels per petiole and possibly by the upregulation of some of the aquaporins measured in the leaf. These results suggest that not only plant water status but also the light environment at the leaf level affected leaf and petiole hydraulics.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239370,"idioma_id":4,"titulo":"Identity and parentage of some South American grapevine cultivars present in Argentina","resumen":"Background and Aims: Based on 19 nuclear simple sequence repeat markers and parental analysis, we aimed to identify and propose the pedigree of different accessions held at the Estaci&oacute;n Experimental Agropecuaria Mendoza of the Instituto Nacional de Tecnolog&iacute;a Agropecuaria germplasm collection. The results were compared with data recorded in large, international databases. Methods and Results: We identified 37 different cultivars, of which 18 were original and not previously identified. The parentage analysis showed that European cultivars, such as Muscat of Alexandria, Muscat &agrave; Petits Grains, List&aacute;n Prieto, Mollar Cano and Malbec, were involved in natural crossings resulting in different South American cultivars. Conclusions: Many of the cultivars identified here represent unique individuals based on their genotype. The number of cultivars that participated as progenitors in the origin of South American germplasm is higher than previously thought. Significance of the Study: Germplasm collections planted many years ago play a key role in the conservation and characterisation of genotypes that otherwise may have been lost. It is highly probable that there might be other genotypes not identified and mixed in old vineyards. The identification, rescue and conservation of these genotypes are a challenge to preserve the existing genetic variability.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239372,"idioma_id":4,"titulo":"Evidence of chromosomal localization of ermTR in strains of Streptococcus agalactiae","resumen":"Streptococcus agalactiae (GBS) is the leading cause of severe invasive infections in infants less than three months. Meningitis, pneumonia and sepsis are the leading cadres in these children. These infections are described as the most serious that an individual may suffer in their first hours of life, the maternal transmission is the main route of infection (95%). Although intrapartum antibiotic prophylaxis (IAP) with penicillin can significantly decrease neonatal GBS diseases, rates of resistance to antibiotics recommended for pregnant women allergic to penicillin, such as clindamycin and erythromycin, have increased. Among the mechanisms of resistance are changes in the target site mediated by erm genes frequently associated with transposons (conjugative and non-conjugative) on chromosome or plasmid. The genomic location of these genes is relevant for its potential interspecific horizontal transmission. The aim of this study was to determine the location of ermTR gene, one of the most reported in GBS. Three strains of GBS were selected for their history of phenotypic resistance and the presence of ermTR gene. The identification of GBS strains was confirmed by conventional biochemical tests. The extraction and purification of plasmid, cromosomal and total DNA were performed with commercial kits. The extraction control and\/or chromosomal plasmids contamination was monitored by PCR with target in the 16S gene. Assays location of ermTR gene was performed using specific PCR. In the development of PCR for ermTR gene amplification a single sharp band of the expected size was obtained. Location assays show the presence of this ermTR gene into the chromosomal DNA of all the strains. In conclusion, the chromosomal location of the ermTR gene was determined and is necessary to continue with further studies of genomic context to contribute to the knowledge of resistance to macrolides and lincosamides.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239374,"idioma_id":4,"titulo":"Excitation-emission fluorescence-kinetic data obtained by Fenton degradation. Determination of heavy-polycyclic aromatic hydrocarbons by four-way parallel factor analysis","resumen":"For the first time, a simple and environmentally friendly third-order\/four-way calibration was applied for the simultaneous determination of five heavy-polycyclic aromatic hydrocarbons (PAHs) in interfering environments. The kinetic evolution of the Fenton degradation of benzo[a]pyrene, dibenz[a,h]anthracene, benzo[b] fluoranthene, benzo[k]fluoranthene and benz[a]anthracene was followed by recording full excitation-emission fluorescence matrices (EEFMs) of the samples at different reaction times, obtaining third-order EEFM-kinetic(EEFM-K) data. The sensitivity of the method was increased by carrying out the reaction in the presence of methyl-&#946;-cyclodextrin. The four-way parallel factor (PARAFAC) algorithm, which was used for data processing, exploits the second-order advantage, allowing analyte concentrations to be estimated even in the presence of an uncalibrated fluorescent background. The clear superiority of the applied approach in comparison with secondorder\/three-way calibration performed with unreacting EEFMs is demonstrated, using two sets of samples withforeign compounds with particular spectral profiles. In one of the latter sets, the existence of a third-order advantage was explored and discussed. The feasibility to directly determine parts-per-trillion concentration levels of PAHs after a very simple solid-phase extraction with C18 membranes is established with natural water samples containing uncalibrated constituents.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239375,"idioma_id":4,"titulo":"Advantages of data fusion. First multivariate curve resolution analysis of fused liquid chromatographic second-order data with dual diode array-fluorescent detection","resumen":"For the first time, liquid chromatography-diode array detection (LC-DAD) and liquid-chromatography fluorescence detection (LC-FLD) second-order data, collected in a singlechromatographic run, were fused and chemometrically processed for the quantitation of coeluting analytes. Two different experimental mixtures composed of fluorescent and nonfluorescent endocrine disruptors were analyzed. Adequate pretreatment of the matrices before their fusion was crucial to attain reliable results. Multivariate curve resolution-alternating least-squares (MCR-ALS) was applied to LC-DAD, LC-FLD, and fused LC-DAD-FLD data. Althoughdifferent degrees of improvement are observed when comparing the fused matrix results in relation to those obtained using a single detector, clear benefits of data fusion are demonstrated through: (1) the obtained limits of detection in the ranges 2.1&#8722;24 ng mL&#8722;1 and 0.9&#8722;6.3 ng mL&#8722;1 for the two evaluated systems and (2) the low relative prediction errors, below 7% in all cases, indicating good recoveries and precision. The feasibility of fusing data and its advantages in the analysis of real samples was successfully assessed through the study of spiked tap, underground, and river water samples.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239376,"idioma_id":4,"titulo":"A road map for multi-way calibration models","resumen":"A large number of experimental applications of multi-way calibration are known, and a variety of chemometric models are available for the processing of multi-way data. While the main focus has been directed towards three-way data, due to the availability of various instrumental matrix measurements, a growing number of reports are being produced on order signals of increasing complexity. The purpose of this review is to present a general scheme for selecting the appropriate data processing model, according to the properties exhibited by the multi-way data. In spite of the complexity of the multi-way instrumental measurements, simple criteria can be proposed for model selection, based on the presence and number of the so-called multi-linearity breaking modes (instrumental modes that break the low-rank multi-linearity of the multi-way arrays), and also on the existence of mutually dependent instrumental modes. Recent literature reports on multi-way calibration are reviewed, with emphasis on the models that were selected for data processing.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239377,"idioma_id":4,"titulo":"Fine-scale root community structure and below-ground responses to grazing show independence from above-ground patterns","resumen":"QuestionRoot biomass distribution and below-ground processes are the main drivers of plant community structure and dynamics in arid rangelands. However, despite their relevance, below-ground plant responses to disturbance regimes remain poorly understood. This knowledge is a pressing issue since most of our ideas derive from extrapolating above-ground ecological theory and data. Here, we asked how domestic grazing management changes (intensification and abandonment) impact on both below-ground species co-occurrence at microsite level (point-richness) in relation to above-ground patterns and below-ground biomass distribution of dominant graminoid species across different soil layers.LocationPatagonian steppe, Argentina.MethodsWe sampled and compared ungrazed, moderately grazed and intensively grazed steppes. We evaluated below- and above-ground point-richness (microsite level: 6-cm diameter), as well as total and specific root biomass in the top 20 cm of soil along 50-m transects in commercial paddocks.ResultsWe found independence between fine-scale below- and above-ground responses. Below-ground point-richness was at least three times higher than above-ground point-richness. Besides, below-ground point-richness decreased from 4.2 species in ungrazed sites to 3.4 species in intensively grazed ones. Neither grazing intensification nor abandonment changed total root biomass, although intensification changed the root biomass composition, reducing preferred and increasing non-preferred grass species. Strikingly, below-ground point-richness and total root biomass did not differ between microsites covered and not covered by vegetation. This pattern was not affected by grazing.ConclusionsOur findings showed a higher degree of fine-scale below-ground species co-occurrence than above-ground in this Patagonian steppe. The intensification of grazing slightly decreased below-ground species co-occurrence and changed root composition (species abundance), although grazing management did not modify the high degree of independence between below- and above-ground structure. Even though intensive grazing markedly decreases above-ground biomass, total below-ground biomass does not vary along a wide range of grazing conditions. In general, most of our knowledge about vegetation responses to grazing is based on above-ground information, assuming that below-ground patterns and processes are analogous to those above-ground. This study suggests that below- and above-ground community structure at fine-scale are not strongly correlated and they can be differentially affected by grazing.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239379,"idioma_id":4,"titulo":"Clustering stability for automated color image segmentation","resumen":"Clustering is a well-established technique for segmentation. However, clustering validation is rarely used for this purpose. In this work we adapt a clustering validation method, Clustering Stability (CS), to automatically segment images. CS is not limited by image dimensionality nor by the clustering algorithm. We show clustering and validation acting together as a data-driven process able to find the optimum number of partitions according to our proposed color-texture feature representation. We also describe how to adapt CS to detect the best settings required for feature extraction. The segmentation solutions found by our method are supported by a stability score named STI, which provides an objective quantifiable metric to obtain the final segmentation results. Furthermore, the STI allows to compare multiple alternative solutions and select the most appropriate according to the index meaning. We successfully test our procedure on texture and natural images, and 3D MRI data.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239380,"idioma_id":4,"titulo":"ELSA 2016 Cohort: Alcohol, Tobacco, and Marijuana Use and Their Association with Age of Drug Use Onset, Risk Perception, and Social Norms in Argentinean College Freshmen","resumen":"The transition from high school to college is a high-risk stage for the initiation and escalation of substance use. Substance use and its associated risk factors have been thoroughly described in developed countries, such as the United States, but largely neglected in Argentina, a South American country with patterns of a collectivist culture. The present cross-sectional study describes the occurrence of alcohol, tobacco, and marijuana use and the association between these behaviors and the age of onset of substance use and cognitive (i.e., risk perception) and social (i.e., prescriptive) variables in a large sample of Argentinean college freshmen (n D 4083, 40.1% men; mean age D 19.39 - 2.18 years). The response rate across courses was 90% and was similarly distributed across sex. Participants completed a survey that measured substance use (alcohol [with a focus on heavy drinking and binge drinking behaviors], tobacco, and marijuana), age of onset of the use of each substance, perceived risk associated with various substance use behaviors, prescriptive norms associated with substance use, and descriptive norms for alcohol use (AU). The results indicated that AU is nearly normative (90.4 and 80.3% with last year and last month use, respectively) in this population, and heavy drinking is highly prevalent (68.6 and 54.9% with heavy episodic and binge drinking, respectively), especially among those with an early drinking onset (97.8 and 93.6% with last year and last month use and 87.8 and 76.3% with heavy episodic and binge drinking, respectively). The last-year occurrence of tobacco and marijuana use was 36 and 28%, respectively. Early substance use was associated with the greater use of that specific substance. The students overestimated their same-sex friend´s AU, and women overestimated the level of AU of their best male friend. At the multivariate level, all of the predictors, with the exception of the parents´ prescriptive norms, significantly explained the frequency of marijuana and tobacco use and frequency of hazardous drinking. Overall, despite important cultural and contextual differences between Argentina and the United States, our findings suggest that certain vulnerability factors have a similar influence across these cultural contexts.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239383,"idioma_id":4,"titulo":"Total Leishmania antigens with Poly(I:C) induce Th1 protective response","resumen":"Aims: Our proposal was to develop a vaccine based on total Leishmania antigens (TLA) adjuvanted with polyinosinic-polycytidylic acid [Poly(I:C)] able to induce a Th1 response which can provide protection against Leishmania infection.Methods and Results: Mice were vaccinated with two doses of TLA-Poly(I:C) administered by subcutaneous route at three week interval. Humoral and cellular immune responses induced by the immunization were measured. The protective efficacy of the vaccine was evaluated by challenging mice with infective promastigotes of Leishmania (Leishmania) amazonensis into the footpad. Mice vaccinated with TLA-Poly(I:C) showed a high anti-Leishmania IgG titer, as well as increased IgG1 and IgG2a subclass titers compared with mice vaccinated with the TLA alone. The high IgG2a indicated a Th1 bias response induced by the TLA-Poly(I:C) immunization. Accordingly, the cellular immune response elicited by the formulation was characterized by an increased production of IFN-&#947; and no significant production of IL-4. The TLA-Poly(I:C) immunization elicited good protection, which was associated with decreased footpad swelling, a lower parasite load and a reduced histopathological alteration in the footpad. Conclusion: Our findings demonstrate a promising vaccine against cutaneous leishmaniasis that is relatively economic and easy to develop and which should be taken into account for preventing leishmaniasis in developing countries.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239385,"idioma_id":5,"titulo":"EXPLORANDO CONDICIONANTES EN LAS DECISIONES ACADÉMICAS DE LA UNIVERSIDAD PÚBLICA","resumen":"El presente proyecto se enmarca dentro de la trayectoria de investigación que el grupo Análisis del Sistema Universitario (perteneciente a la Facultad de Ciencias Económicas y Sociales de la Universidad Nacional de Mar del Plata e integrado  en parte por los autores de este trabajo), ha realizado sobre los procesos decisorios. Durante varios años se han analizado los distintos condicionantes que inciden en la toma de decisiones, tanto individuales y grupales como organizacionales.Con el objetivo de profundizar la investigación se pretende hacer foco en las decisiones del área académica de la universidad pública argentina. Para ello se intentará la construcción de un guión de entrevista que permita explorar sobre los diferentes condicionantes que influyen en la calidad de dichos procesos.Se espera que la información relevada sirva para contribuir a la mejora de las políticas de gestión universitaria y, especialmente, se constituya en una herramienta para favorecer el desarrollo de la profesión docente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239386,"idioma_id":4,"titulo":"n++GaN Regrowth Technique Using Pico-second Laser Ablation to Form Non-alloy Ohmic Contacts","resumen":"Non-alloy ohmic contacts were implemented based on the heavily Germanium-doped GaN regrown layer by using Pico-Second Laser ablation technique for the first time. Owing to the enhanced surface diffusion of the ablated high-energy atoms, smoothly refilled epitaxial layers were achieved in the AlGaN\/GaN recess regions. Selective growth was successfully carried out by using HSQ film. Contact resistance of ~0.17 &Omega;&middot;mm with a specific contact resistance in the order of ~10&minus;&#8311; &Omega;&middot;cm&sup2; was obtained by using non-alloy Hf\/Al\/Ti metal stacks.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239389,"idioma_id":5,"titulo":"Trayectorias que inciden en las prácticas de enseñanza de teatro. Relato de una investigación en curso","resumen":"En este artículo se presentan algunos avances realizados en torno alproyecto de investigación denominado ?Prácticas de enseñanza delTeatro. Saberes y habilidades en contexto?. En el mismo nospropusimos indagar acerca de la incidencia de las trayectoriasformativas de los profesores de Teatro en sus intervenciones educativas,en espacios diferenciados y en sus modos de resolver la enseñanza.Estas prácticas situadas en diferentes contextos de intervención suponenuna complejidad que requiere de una amplia gama de recursosmetodológicos, los que se pueden inscribir principalmente en laperspectiva cualitativa de la investigación social","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239390,"idioma_id":5,"titulo":"EPILEPSIA Y SINDROMES EPILEPTICOS EN PERROS Y GATOS","resumen":"La epilepsia es una enfermedad cerebral caracterizada por una predisposición duradera a la generación de crisis epilépticas. Usualmente se aplica esta definición cuando se presentan al menos 2 crisis no provocadas con una diferencia de tiempo mínima de 24 horas. El término no provocado implica la ausencia de un factor transitorio o reversible que disminuya el umbral convulsivo y genere crisis en un determinado momento.Una crisis provocada por un factor transitorio que actúa sobre un cerebro por lo demás normal para reducir temporalmente el umbral de crisis no se considera como epilepsia. El término crisis provocada puede ser considerado como sinónimo de crisis reactiva o sintomática.La epilepsia es heterogénea en cuanto a sus etiologías. Aún concebida como una enfermedad, incluye un conjunto de trastornos de distinto pronóstico y tratamiento, que requieren un protocolo diagnóstico exhaustivo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239393,"idioma_id":4,"titulo":"Main and epistatic QTL analyses for Sclerotinia Head Rot resistance in sunflower","resumen":"Sclerotinia Head Rot (SHR), a disease caused by Sclerotinia sclerotiorum, is one of the most limiting factors in sunflower production. In this study, we identified genomic loci associated with resistance to SHR to support the development of assisted breeding strategies. We genotyped 114 Recombinant Inbred Lines (RILs) along with their parental lines (PAC2 ?partially resistant?and RHA266 ?susceptible?) by using a 384 single nucleotide polymorphism (SNP) Illumina Oligo Pool Assay to saturate a sunflower genetic map. Subsequently, we tested these lines for SHR resistance using assisted inoculations with S. sclerotiorum ascospores. We also conducted a randomized complete-block assays with three replicates to visually score disease incidence (DI), disease severity (DS), disease intensity (DInt) and incubation period (IP) through four field trials (2010?2014). We finally assessed main effect quantitative trait loci (M-QTLs) and epistatic QTLs (E-QTLs) by composite interval mapping (CIM) and mixed-model-based composite interval mapping (MCIM), respectively. As a result of this study, the improved map incorporates 61 new SNPs over candidate genes. We detected a broad range of narrow sense heritability (h2) values (1.86?59.9%) as well as 36 M-QTLs and 13 E-QTLs along 14 linkage groups (LGs). On LG1, LG10, and LG15, we repeatedly detected QTLs across field trials; which emphasizes their putative effectiveness against SHR. In all selected variables, most of the identified QTLs showed high determination coefficients, associated with moderate to high heritability values. Using markers shared with previous Sclerotinia resistance studies, we compared the QTL locations in LG1, LG2, LG8, LG10, LG11, LG15 and LG16. This study constitutes the largest report of QTLs for SHR resistance in sunflower. Further studies focusing on the regions in LG1, LG10, and LG15 harboring the detected QTLs are necessary to identify causal alleles and contribute to unraveling the complex genetic basis governing the resistance.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239394,"idioma_id":4,"titulo":"Fossil mammals of the Quebrada de los Colorados Formation (late middle Eocene) at the locality of La Poma, Salta Province, Argentina","resumen":"An anatomical and taxonomic analysis of the mammalian record in the locality of La Poma in Salta Province,Argentina, is here presented. This record consists in two specimens exhumed in levels of the Quebrada delos Colorados Formation referred to the middle late Eocene. The first specimen is represented by a partialskull preserving mostly the rostrum and some dental pieces and was identified as a member of Leontiniidae,although it does not bear enough information for generic or specific determination. The second specimenis represented by more complete material, preserving much of the dentition. It was identified as a newspecies of the genus Pampahippus, traditionally included in the paraphyletic family Notohippidae. Theleontiniid here studied presents several plesiomorphic features identified in other taxa of northwesternArgentina, and this material represents a new example of a pre-Deseadan basal morphotype within thefamily. Regarding the new species of Pampahippus, it shows clear signs of rising hypsodonty, representingthe first case for a notoungulate lineage in the Paleogene of northwestern Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239395,"idioma_id":4,"titulo":"Cranial anatomy of an Eocene notoungulate mammal from northwestern Argentina with special reference on the ear region","resumen":"A detailed anatomical analysis is here presented focused on a notoungulate skull recovered from sediments of the lower part of the Quebrada de los Colorados Formation (LC I; late middle Eocene), cropping out in Salta Province, Argentina. The material was identified as a Toxodontia, although it does not exhibit information useful enough for its generic or even familiar assignment. The description was mainly focused on the basicranium and the auditory region (especially the petrosal and auditory ossicles) given the better preservation of these parts in the specimen. Additionally, a phylogenetic analysis was conducted based on previous studies dealing with a wide sample of South American Native Ungulates. This specimen exhibits some traits traditionally mentioned for the suborder Toxodontia, such as the horizontal bullar septum, and others recently regarded as synapomorphies of Notoungulata, including the lateral location of the tensor tympani fossa and the expanded medial margin of the petrosal. However, it also shows some unexpected features for that suborder of notoungulates, such as the presence of a strongly curved promontorium. The study of this skull increases our knowledge of the auditory anatomy of Eocene Toxodontia and yields a good opportunity to test current phylogenetic hypothesis, mostly based on Neogene representatives.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239396,"idioma_id":5,"titulo":"Cultura, Identidad e Imagen Organizacional. Un estudio de caso a partir del discurso de docentes y personal de apoyo de una Universidad Pública Argentina","resumen":"Al proveer a los miembros de una organización de un marco de referencia socialmente compartido e inconsciente que los orienta en su forma de percibir, interpretar y reaccionar ante los eventos, la cultura organizacional constituye un fuerte condicionante a la toma de decisiones, influyendo en la racionalidad individual, grupal y organizacional. A su vez, a los efectos de evitar análisis excesivamente simplificadores, este fenómeno requiere ser estudiado en su interacción con la identidad y la imagen organizacional. Utilizando una metodología de estudio de caso, sustentada en la triangulación de fuentes cuantitativas y cualitativas, en este trabajo se realiza un diagnóstico de la cultura, la identidad y la imagen organizacional de una Facultad perteneciente a una Universidad Pública Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239397,"idioma_id":5,"titulo":"Una aproximación al crecimiento comercial de la Región Río de la Plata durante la segunda mitad del siglo XVIII.","resumen":"ARTICULO EN PRENSA. APROBADO PARA SU PUBLICACIÓN. Este artículo analiza algunos de los mecanismos de enriquecimiento de los comerciantes rioplatenses y el crecimiento comercial de la Región Río de la Plata durante las últimas décadas del siglo XVIII. La hipótesis que planteamos es que se produjo una triangulación en donde por las mercancías que ingresaban desde la península española se enviaban cueros y hacia el interior de América se intercambiaban esas mercancías por metales preciosos. Esos metales preciosos se acumularon en la Región Río de la Plata y en los comerciantes que participaron de esta actividad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239398,"idioma_id":5,"titulo":"El negocio del cuero en el Río de la Plata a fines del siglo XVIII","resumen":"Resumen: Este trabajo pretende efectuar una síntesis que muestre un panorama completo de todo el circuito de la producción y comercialización de los cueros vacunos en el Río de la Plata a finales del siglo XVIII. Es decir, un sumario de todas las actividades económicas y los agentes que intervenían desde la matanza del animal hasta la estiba del cuero dentro de la embarcación que lo llevará a través del océano Atlántico, al mercado consumidor. Al mismo tiempo, se incluirán los resultados de recientes investigaciones sobre la circulación de los cueros dentro de la región y su posterior exportación y sobre los agentesinvolucrados en esas actividades. De esta manera, se busca mostrar la complejidad de la producción y comercialización de los cueros a fines del siglo XVIII, que los agentes identificados se pueden incluir en distintas categorías ocupacionales y, además, destacar que la mayor parte de la población estaba vinculada de alguna manera al negocio de los cueros vacunos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239401,"idioma_id":4,"titulo":"Hub-enhanced noise-sustained synchronization of an externally forced FitzHugh-Nagumo ring","resumen":"A ring of FitzHugh?Nagumo units with antiphase coupling between their activator fields and submitted to a adiabatic harmonic subthreshold signal, is in turn globally coupled in electrical mode with the activator field of a hub. Noise sustained synchronization of neural activity with the signal is numerically observed, and theoretically characterized. The different dynamical regimes are elucidated using the concept of nonequilibrium potential, and the hub is found to promote network synchronization. The minimum noise intensities triggering the activation and synchronization processes are estimated in the framework of a three-neuron model.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239403,"idioma_id":4,"titulo":"Description Of The Burrowing Owl (Athene cunicularia) Diet In La Angostura Reservoir, Tafí Del Valle, Tucumán, Argentina","resumen":"The Burrowing owl (Athenes cunicularia) has been widely studied in terms of its eating habits both in our country and other countries in North and South America. However, there is little information about it in adjacent areas to aquatic environments. The aim of this work was to determine the feeding of A. cunicularia by the study of the pellets throughout a year in the perilago of La Angostura Reservoir. The study area is located in Tafí del Valle, in the western part of the province of Tucumán, Argentina, approximately to the 26 ° 55'S, 65° 41'W, at about 2000 meters above sea level. The reservoir, with an area of 980 ha, covering a perimeter of 12 km, including peripheral bodies of flooding. Five nests (caves) and places where they rest and watch (hangers) were identified. Sampling was conducted from april 2013 to march 2014. During this period 626 pellets were collected, weighed, measured and analyzed. Taxonomic determinations were made to the highest possible level. A total of 15430 items (dams), among Mammals, Birds, Amphibians, Insects and Chelicerates was identified. The most abundant were the insects of the Order Coleoptera with 6081 items, then Mammals with 463 items and finally the insects oh the Family Acridae (grasshoppers) Order Orthoptera with 416 items. A. cunicularia showed a generalist food and variations of items throughout the year. From this work can be assessed the role that could comply with the tropical screech Burrowing owl as biological controller of population growth of their prey.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239404,"idioma_id":4,"titulo":"Bird Communities Of The Añatuya Marshlands, An Important Bird And Biodiversity Area (IBA) In Santiago Del Estero, Argentina","resumen":"The Añatuya marshlands are located in the departments of Taboada and Avellaneda, 270 km from Santiago del Estero(28°48´33.1' S; 62°38´39.7' W). They are formed by flood and waterlogging from the Salado River. The wetland, of approximately 90,000 ha, presents areas of shallow waters with marshy vegetation and also deeper open waters. The aim ofthis work was to carry out a preliminary study of the bird community in this site, considered as an import Bird and Biodiversity Area (IBA). Strip transect surveys, fixed point radius and vehicle tours between the 2012 to 2014, divided into the four seasons, were performed. The number of individuals, species and habitats used was recorded. The relative abundance (RA) and the index of relative importance (RI) were calculated. There were 56 species and 6686 individuals, the two most abundant being Tachycineta leucorrhoa and Progne tapera, followed by Netta peposaca, Dendrocygna bicolor,Plegadis chii, Fulica leucoptera and Himantopus melanurus. Both regional and Nearctic-Neotropical migratory and residentspecies were identified. The richness and abundance of bird species is low compared to other natural wetlands in the dryChaco. This could be due to changes in the environment such as intensive agriculture, overgrazing, logging, sport huntingand infrastructure. Since birds are an indicator of the quality of the environment and since the Añatuya Marshlands an IBA, itis important that studies be continued to obtain a baseline from which to consider guidelines for the management andconservation of the region.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239408,"idioma_id":4,"titulo":"Energy reserves mobilization: Strategies of three decapod species","resumen":"In food deprivation assays, several different responses have been observed in crustaceans.However, studying energy reserves utilization among more than one species during the same starvation period has not yet been performed, particularly to discern whether the responses are due to intrinsic and\/or environmental factors. We hypothesize that decapod species with similar feeding habits have the same strategies in the use of energetic reserves during starvation, even though they inhabit different environments. The aim of this study was to compare the energy reserves mobilization of three decapods species (Cherax quadricarinatus,Palaemon argentinus and Munida gregaria) with similar feeding habits, exposed to similar food deprivation conditions. The crayfish, shrimp and squat-lobster were experimentally kept at continuous feeding or continuous starvation throughout 15 days. Every 3rd day, the midgut gland index (MGI), and the glycogen, lipid and protein contents were measured in the midgut gland (MG) and pleon muscle. Palaemon argentinus mobilized more reserves during starvation, followed by C. quadricarinatus, and the last M. gregaria. Thestarved shrimps presented low MGI, whereas MG showed a reduction in glycogen (from day 6 to 15), lipid (from day 3 to 15), and protein levels (at day 9 and 15) while in their muscle, lipid reserves decreased at days 3 and 6. In C. quadricarinatus, the most affected parameters in the MG were MGI, glycogen (from day 6 to 15), and lipids (at day 12 and 15). In the MG of M. gregaria only the glycogen was reduced during fasting from 3 to 15 days. Even though the three studied species have similar feeding habitats, we found that their energetic profile utilization is different and it could be explained by the habitat, life span, temperature, organ\/tissue, and metabolism of the species. Our results may be useful to understand the several different responses of crustaceans during starvation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239410,"idioma_id":5,"titulo":"Retextualización de géneros: una estrategia para la comprensión y producción de textos en lengua extranjera","resumen":"Las prácticas comunicativas y sociales que exige el aprendizaje de una lengua extranjera, requiere de múltiples posibilidades de abordajes del discurso y la cultura. Es por esto que desde Portugués Lengua Extranjera tomamos la propuesta teórico-práctica de instalar  la observación y el análisis de contextos discursivos múltiples (como los cotidianos, regionales, literarios, científicos, periodísticos, etc.), para luego focalizar la atención, la mirada y la producción en los contextos académicos y profesionales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239411,"idioma_id":4,"titulo":"Advantages of Data Fusion: First Multivariate Curve Resolution Analysis of Fused Liquid Chromatographic Second-Order Data with Dual Diode Array-Fluorescent Detection","resumen":"For the &#64257;rst time, liquid chromatography-diode&nbsp; array detection&nbsp; (LC-DAD)&nbsp; and&nbsp; liquid-chromatography&nbsp;&nbsp; &#64258;uorescence detection (LC-FLD) second-order data, collected&nbsp; in&nbsp; a&nbsp; single chromatographic&nbsp; run, were fused and chemometrically&nbsp; processed for the quantitation of coeluting analytes. Two di&#64256;erent experimental mixtures composed of &#64258;uorescent and non&#64258;uorescent endocrine disruptors were analyzed.&nbsp; Adequate pretreatment of the matrices before their fusion was crucial to attain reliable results. Multivariate curve resolution-alternating least-squares (MCR-ALS) was applied to LC-DAD, LC-FLD, and&nbsp; fused&nbsp;&nbsp; LC-DAD-FLD data.&nbsp; Although di&#64256;erent degrees of improvement are observed when comparing the fused matrix results in relation to those obtained using a single detector, clear bene&#64257;ts of data fusion are demonstrated through: (1) the obtained limits of detection in the ranges 2.1&#8722;24 ng mL&#8722;1 and 0.9&#8722;6.3 ng mL&#8722;1 for the two evaluated systems and (2) the low relative prediction errors, below 7% in all cases, indicating good recoveries and precision. The feasibility of fusing data and its advantages in the analysis of real samples was successfully assessed through the study of spiked tap, underground, and river water samples.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239412,"idioma_id":4,"titulo":"Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping","resumen":"A new methodology involving four-way multivariate calibration with a balanced number of data points in all modes is presented. The method is based on fluorescence excitation-emission matrices modulated by a double pH gradient obtained in a flow injection system. This data array was employed for the quantitation of ciprofloxacin, ofloxacin and norfloxacin in unprocessed urine samples. Due to the presence of potential interfering compounds with overlapping profiles in the analyzed samples, it is required to achieve the second-order advantage. The four-way arrays obtained were processed by parallel factor analysis (PARAFAC), attaining satisfactory results with relative errors of prediction (REP%) between 3% and 7.5% in the analyzed samples for all analytes. The average limit of detection (mg L&minus;&nbsp;1) was 0.035 for norfloxacin and ofloxacin and 0.028 for ciprofloxacin.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239413,"idioma_id":4,"titulo":"Plant based compounds with potential as Push - Pull stimuli to manage behavior of leaf cutting ants","resumen":"Leaf-cutting ants are a serious pest of young forestry plantations. Currently, themain controlmethodis the use of broad-spectrum insecticides, which have a negative effect on non-target organisms and the environment. In this work, plant-based compounds were evaluated in laboratory assays with Acromyrmex ambiguus Emery (Hymenoptera: Formicidae) for their potential use as repellent and attractant stimuli to be used in a push-pull strategy. Farnesol, a sesquiterpene present in many essential oils, was tested as a repellent at doses of 10, 50, and 100 mg. Its distance of action was studied by comparing the repellent effect of farnesol in a situation in which ants had to touch the farnesol in order to reach the food source in comparison to when ants could reach the food source without getting into direct contact with it. Different parts of the orange fruit (pulp and peel) were evaluated and compared as attractants, given that citrus-based baits are among the most popular attractants used. Results from laboratory bioassays indicated that farnesol is repellent at doses of 50 mg and acts upon contact or at a very short distance. Furthermore, orange pulp was more attractive than the peel, and volatile compounds were highly responsible for the attraction.When both stimuli were tested simultaneously in a laboratory experiment, repellency of farnesol was enhanced in the presence of orange pulp odor. When tested in a field push-pull experiment, the results also showed a good repellent effect of farnesol as well as an attractant effect of the orange pulp. These results encourage long-term studies with these substances in a field setting and suggest that repellents can be enhanced by the use of attractants tomanage leaf-cutting ants behavior.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239415,"idioma_id":5,"titulo":"ANÁLISIS DE LOS DOS MECANISMOS DE MUERTE CELULAR POR RADIACIÓN IONIZANTE EN MONOCAPAS, ESFEROIDES Y TUMORES TRASPLANTADOS","resumen":"Se testea una relación entre la razón de mejora por oxigeno (OER) y los parámetros de radiosensibilidad del modelo Lineal Cuadrático (LQ) en condiciones hipóxicas y aeróbicas de oxigenación, en varias líneas celulares cultivadas en monocapas, esferoides y tumores trasplantados (xenograft). Considerando dicha relación aparecen los dos mecanismos de muerte celular por irradiación. Se comparan ajustes de la Fracción de Sobrevida (SF) enambas condiciones de oxigenación usando el modelo LQ. Los datos son obtenidos de bibliografía. Se muestra la existencia de dichos mecanismos y su implicancia en los diferentes sistemas estudiados. Se determina la validez de uno u otro mecanismo en cada caso, y la dependencia de OER con la dosis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239416,"idioma_id":4,"titulo":"Tubulin is retained throughout the human hematopoietic\/erythroid cell differentiation process and plays a structural role in sedimentable fraction of mature erythrocytes","resumen":"We investigated the properties of tubulin present in the sedimentable fraction ('Sed-tub') of human erythrocytes, and tracked the location and organization of tubulin in various types of cells during the process of hematopoietic\/erythroid differentiation. Sed-tub was sensitive to taxol\/nocodazole (drugs that modify microtubule assembly\/disassembly), but was organized as part of a protein network rather than in typical microtubule form. This network had a non-uniform 'connected-ring' structure, with tubulin localized in the connection areas and associated with other proteins. When tubulin was eliminated from Sed-tub fraction, this connected-ring structure disappeared. Spectrin, a major protein component in Sed-tub fraction, formed a complex with tubulin. During hematopoietic differentiation, tubulin shifts from typical microtubule structure (in pro-erythroblasts) to a disorganized structure (in later stages), and is retained in reticulocytes following enucleation. Thus, tubulin is not completely lost when erythrocytes mature; it continues to play a structural role in the Sed-tub fraction.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239417,"idioma_id":5,"titulo":": ENTRE TODOS- Producción Escrita del Programa del Voluntariado, Adolescencia, Salud y Género.","resumen":"La recuperación de historias de los trabajos que los docentes realizan en las aulas, en este caso, en la escuela secundaria, posibilita volver sobre las propias prácticas, analizarlas, reflexionar sobre las mismas y poder proponer actividades, estrategias, etc  para superar los aspectos evaluados como negativos o debilidades. Ahora bien, si a esas escrituras se le suman las voces de los actores  principales, el producto se enriquece completa y facilita reformulaciones, ampliaciones y transformación de las propias prácticas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239418,"idioma_id":5,"titulo":"IV Congreso Latinoamericano de Arte, Educación, Comunicación y Discurso","resumen":"Proponemos un espacio para el encuentro, el debate, la reflexión, el disenso, la participación individual y grupal cuyos ejes son: el arte, la educación, la comunicación y los discursos Latinoamericanos, pero no como disciplinas aisladas sino considerando a estos cuatro campos del conocimiento, como ámbitos constitutivos de una misma realidad compleja, en la cual el ser humano, su tiempo y espacio constituyen diferentes aspectos de la misma.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239419,"idioma_id":5,"titulo":"Un Enfoque de Decisión Multicriterio Difuso aplicado a un problema de selección en el sector de la construcción","resumen":"El trabajo propone un modelo de decisión multicriterio TOPSIS en un entorno difuso para resolver un problema de localización de un barrio privado en el cual el decisor se enfrenta con estimaciones de los datos de entrada expresados como preferencias cualitativas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239423,"idioma_id":4,"titulo":"A NEW DEPIGMENTING ANTIFUNGAL METHYLATED GRINDELANE FROM GRINDELIA CHILOENSIS","resumen":"The new methylated grindelane diterpenoid, 7&#946;-hydroxy-8(17)-dehydrogrindelic acid (1b), together with the known 7&#945;-hydroxy-8(17)-dehydrogrindelic acid (2a), 6-oxogrindelic acid (3a), 4&#946;-hydroxy-6-oxo-19-norgrindelic (4a), 19-hydroxygrindelic acid (5a), 18-hydroxygrindelic acid (6a), 4&#945;-carboxygrindelic acid (7a), 17-hydroxygrindelic acid (8a), 6&#945;-hydroxy grindelic acid (9a), 8,17-bisnor-8-oxagrindelic acid (10a), 7&#945;,8&#945;-epoxygrindelic acid (11a), and strictanonic acid (12a) as methyl esters were obtained from an Argentine collection of Grindelia chiloensis Cabr. Their structures and relative configurations were established on the basis of spectroscopic analysis. Chloroform extract from the aerial parts and their pure compounds were evaluated for their antifungal and depigmenting effects. Methyl ester derivative of 10a (10b) exhibited a remarkable mycelial growth inhibition against Botritis cinerea with an IC50 of 13.5 &#956;g ml&#8722;1. While the new grindelane 1b exerted a clear color reduction of the yellow-orange pigment developed by Fusarium oxysporum against UV-induced damage.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239427,"idioma_id":10,"titulo":"Cenas para pensar a educação na diferença","resumen":"Este ensaio se oferece como um exercício de escrita feito a quatro mãos como aposta política numa escrita coletiva e, também, apenas a duas mãos, como uma aposta e defesa da solidão da escritura. Ensaio composto por fragmentos que se enunciam na sua força expressiva como 'cenas' que talvez permitam pensar a educação na diferença. Expressão de um bom encontro produzido entre duas professoras de universidades públicas - brasileira e argentina-que, atuando na formação de professores inicial e continuada ainda se perguntam pela possibilidade de criação de uma cena educativa outra na qual se sacudam as práticas da mesmidade para apostar na irredutível irrupção de experiências contra hegemônicas. As cenas aquí apresentadas são um efeito de nossas inscursões por diversas escolas públicas argentinas e brasileiras, conversas entre professores de universidades e escolas básicas e entre professores e alunos em formação, entre escolas e familias. Cenas que inspiram um ensaio que longe de apresentar resultados supostamente objetivos das nossas investigações,  mantém as preguntas e o campo problemático ascesso encharcado de interrogações, irrupções e surpressas. Nada para ser seguido como modelo. Nada para ser contabilizado como dado. Apenas cenas entre educação e diferença. A primeira cena abre a  pergunta: o que faz a escola com a diversidade?  A  figura escolhida para esta problematização é a do  'desengonçador'. A segunda cena se apresenta como uma crónica na qual o espaço da formação e a condição irredutível da diferença são testados e tensionados cotidianamente como um exercicio de invenção do nome dos outros.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239428,"idioma_id":4,"titulo":"NeQUICK 2 Total electron content predictions for middle latitudes of North American region during a deep solar minimum","resumen":"The performance of NeQuick 2 model in computing the vertical total electron content (VTEC) over a wide region placed at middle latitudes of North America during the deep solar minimum that occurred in 2008 has been checked. The long term relationship between EUV irradiance and F10.7 solar flux has changed markedly during the cycle 23\/24 minimum with EUV levels decreasing more than expected from F10.7 proxy. A decrease of ionization in the ionosphere could have occurred. Thus, it could be expected that the models overestimate the value of ionospheric parameters for that deep solar minimum. For this study a high density VTEC data grid that covers the Continental United States (CONUS) has been compared with monthly median maps constructed with NeQuick 2.The results show that NeQuick 2 generally gives good predictions for the region which lies between 35°N to 50°N suggesting that nothing exceptional was happening during the 2008 minimum in terms of VTEC NeQuick 2´s predictive capabilities. Taking into account that the modeled value is obtained by integration in height of the electron density profile, NeQuick2 would be assuming an inadequate profile for the few highest deviations observed, between 30°N and 35°N. Overall, the model does not give significant overestimation of VTEC as could be expected.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239433,"idioma_id":5,"titulo":"Alrededor de la medición de la pobreza en la prensa. Dilemas, demandas y saberes","resumen":"En este artículo se exponen algunas conclusiones respecto del tratamiento discursivo que entre 2002 y 2014 le otorgaron distintos diarios de la prensa argentina a la presentación de las estadísticas económicas oficiales sobre pobreza. Desde una perspectiva sociosemiótica y del concepto de verosímil, el objetivo fue entender las condiciones de producción significantes resultado del cruce de dos tipos de discurso diferenciados: el discurso científico-técnico y el discurso periodístico-informativo. Y, a la vez, interrogarnos sobre la especificidad de ese discurso científico-técnico elaborado en las agencias gubernamentales y que circula como palabra oficial.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239435,"idioma_id":4,"titulo":"Biological control of Diloboderus abderus (Coleoptera: Scarabaeidae) larvae using Steinernema rarum CUL (Nematoda: Steinernematidae) and Heterorhabditis bacteriophora SMC (Nematoda: Heterorhabditidae)","resumen":"Theadvance of no-till management systems in agriculture favored the increase of Diloboderusabderus (Sturm) populations in most of the cultivated areas in SouthAmerica. Damage to wheat crops (Triticum aestivum Linnaeus) is caused by the larvae,commonly known as white grubs, which consume seeds and roots, weakening orkilling the plants. Entomopathogenic nematodes (EPNs) are insect parasitesusually used as biological control agents of larvae of Scarabaeidae species. However,a great variability in pathogenicity and virulence against differentwhite grubs has been observed among EPN species and isolates of a singlespecies. The aim of this work was to evaluate the pathogenicity of Steinernemararum (de Doucet) CULisolate, Heterorhabditis bacteriophora (Poinar) SMC isolate and theirsymbiotic bacteria against D. abderus larvae. Wheat plants were grown in plastic potsunder greenhouse conditions andone larva (L1, L2 or L3) of D. abderus was placed in each pot andthen inoculated with 1000 EPNIJs. H.bacteriophora caused 95 and 45 % mortality to L1 and L2,respectively. No L3 mortality caused by the studied isolates was observed. Fieldexperiments were conducted in wheat plots in 2013 and 2014. Treatmentsconsisted of surface application of S. rarum or H. bacteriophora (2.5x 109 IJs\/ha) and chlorpyrifos; control treatments contained only distilledwater. Evaluations were made at day 0, 30 and 60 after treatments by randomlyselecting eight sites from each plot and determining the number of D.abderus L2. Larval populations were reduced in plots treated with H.bacteriophora and chlorpyrifos. Larval populations were reduced in plotstreated with H. bacteriophora and chlorpyrifos. The plots treated with S.rarum did not show differences in the insect population with respect to thecontrol. EPN symbiotic bacteria were injected into the hemocoel of each larvalstage to determine virulence against D. abderus. D. abderuslarval mortality caused by symbiotic bacteria was significantly influenced bybacterial concentration and larval stage. H. bacteriophora showed agreater reproductive capacity than S. rarum. We conclude that H.bacteriophora SMC have potential for use as biological control agents of D.abderus first and second-instar larvae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239440,"idioma_id":4,"titulo":"An Euler-Lagrange Equation Only Depending on Derivatives of Caputo for Fractional Variational Problems with Classical Derivatives","resumen":"In this paper we present advances in fractional variational problems with a Lagrangian depending on Caputo fractional and classical derivatives. New formulations of the fractional Euler-Lagrange equation are shown for the basic and isoperimetric problems, one in an integral form, and the other that depends only on the fractional derivatives of Caputo. Finally, a new exact solution for a particular variational problem is obtained.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239442,"idioma_id":5,"titulo":"Los ambientes acuáticos en arqueología","resumen":"En este trabajo se discute sobre la importancia&nbsp; de los ambientes acuáticos para el estudiodel pasado en arqueología. Aunque el tema es abordado de modo global, elénfasis está puesto en sociedades con economías basadas en la caza, larecolección, la pesca y la horticultura a pequeña escala, y se ilustran conejemplos arqueológicos mayoritariamente regionales. El concepto de ambienteacuático es considerado en su sentido amplio, en el que se incluyen losambientes del interior continental y marinos, y de aguas quietas, móviles,someras y profundas. Luego de una breve presentación sobre el concepto generalde ambiente acuáticos y de su uso a lo largo de &nbsp;la historia de la humanidad, el trabajo seenfoca en tres temas principales. Primero, en los modos y estrategiastecnológicas de explotación de los ambientes acuáticos (navegación, uso delagua, y explotación de minerales, plantas y animales). Luego, en los distintosgrados de intensidad en que las sociedades humanas hicieron uso de estosentornos, para lo cual se definen y caracterizan cuatro modalidades principales(uso puntual, uso ocasional, uso sostenido y uso intensivo) y se derivan algunasexpectativas arqueológicas. Y, por último, se resumen los aspectos principalesde la relación entre los ambientes acuáticos y la comunicación y el simbolismode las sociedades. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239445,"idioma_id":5,"titulo":"Análisis de la colección del Túmulo II de Brazo Largo  (Islas del Ibicuy, provincia de Entre Ríos).","resumen":"In this paper we present the results of the analysis of the Túmulo II del Brazo Largo collection (Lower Delta of the Paraná River), dated circa 750 14C years BP. The archaeofaunal assemblage is dominated by Blastocerus dichotomus, followed by Myocastor coypus, Hydrochoerus hydrochaeris and fish. Also, a numerous and diverse carnivore bone assemblage, which shows clear evidences of skinning, was identified. The bone tool collection presents a wide variety of morphological groups and evidences of harpoon heads manufacture sequence were recorded. The ceramic materials are characterized by the predominance of open medium-sized shapes, with straight walls and convex bases. Incising modes and design elements depicted in the pottery are similar to those reported by other authors in the Paraná Lower Delta, but some decorative units present a wider spatial distribution. The lithic assemblage comprises ground stone tools with little effort invested in their shaping, recycled broken artefacts and worn-out pieces. The bone, lithic and ceramic technology is similar to that described for other archaeological sites in the Lower Delta. The differences between these sites and Goya-Malabrigo contexts probably reflect the cultural diversity described for the Paraná Delta by early sixteenth century historical sources.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239452,"idioma_id":4,"titulo":"Antigenic and immunogenic spectrum of foot-and-mouth disease vaccine strain O1 Campos against representative viruses of topotypes that circulated in Asia over the past decade","resumen":"Identifying vaccine strains to control outbreaks of foot-and-mouth disease virus that could spread to new regions is essential for contingency plans. This is the first report on the antigenic\/immunogenic relationships of the South American O1\/Campos vaccine strain with representative isolates of the three currently active Asian type O topotypes. Virus neutralization tests using O1\/Campos post-vaccination sera derived from cattle and pigs predicted for both species acceptable cross-protection, even after single vaccination, established by r1 values and by expectancy of protection using monovalent or polyvalent vaccines. The results indicate that effective oil vaccines containing the O1\/Campos strain can be used against Asian isolates, expanding the scope of O1\/Campos strain included in vaccine banks to control emergencies caused by Asian viruses, even on single-dose vaccination, and to cover the need of effective vaccines in Asia during systematic vaccination.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239453,"idioma_id":4,"titulo":"Thieno[2,3-b]pyridine derivatives: a new class of antiviral drugs against Mayaro virus","resumen":"Mayaro virus (MAYV) is an arthropod-borne virus and a member of the family Togaviridae, genus Alphavirus. Its infection leads to an acute illness accompanied by long-lasting arthralgia. To date, there are no antiviral drugs or vaccines against infection with MAYV and resources for the prevention or treatment of other alphaviruses are very limited. MAYV has served as a model to study the antiviral potential of several substances on alphavirus replication. In this work we evaluated the antiviral effect of seven new derivatives of thieno[2,3-b]pyridine against MAYV replication in a mammalian cell line. All derivatives were able to reduce viral production effectively at concentrations that were non-toxic for Vero cells. Molecular modeling assays predicted low toxicity risk and good oral bioavailability of the substances in humans. One of the molecules, selected for further study, demonstrated a strong anti-MAYV effect at early stages of replication, as it protected pre-treated cells and also during the late stages, affecting virus morphogenesis. This study is the first to demonstrate the antiviral effect of thienopyridine derivatives on MAYV replication in vitro, suggesting the potential application of these substances as antiviral molecules against alphaviruses. Additional in vivo research will be needed to expand the putative therapeutic applications.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239454,"idioma_id":4,"titulo":"Antigenic and immunogenic spectrum of foot-and-mouth disease vaccine strain O1 Campos against representative viruses of topotypes that circulated in Asia over the past decade","resumen":"Identifying vaccine strains to control outbreaks of foot-and-mouth disease virus that could spread to new regions is essential for contingency plans. This is the first report on the antigenic\/immunogenic relationships of the South American O1\/Campos vaccine strain with representative isolates of the three currently active Asian type O topotypes. Virus neutralization tests using O1\/Campos post-vaccination sera derived from cattle and pigs predicted for both species acceptable cross-protection, even after single vaccination, established by r1 values and by expectancy of protection using monovalent or polyvalent vaccines. The results indicate that effective oil vaccines containing the O1\/Campos strain can be used against Asian isolates, expanding the scope of O1\/Campos strain included in vaccine banks to control emergencies caused by Asian viruses, even on single-dose vaccination, and to cover the need of effective vaccines in Asia during systematic vaccination.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239455,"idioma_id":4,"titulo":"Thieno[2,3-b]pyridine derivatives: a new class of antiviral drugs against Mayaro virus","resumen":"Mayaro virus (MAYV) is an arthropod-borne virus and a member of the family Togaviridae, genus Alphavirus. Its infection leads to an acute illness accompanied by long-lasting arthralgia. To date, there are no antiviral drugs or vaccines against infection with MAYV and resources for the prevention or treatment of other alphaviruses are very limited. MAYV has served as a model to study the antiviral potential of several substances on alphavirus replication. In this work we evaluated the antiviral effect of seven new derivatives of thieno[2,3-b]pyridine against MAYV replication in a mammalian cell line. All derivatives were able to reduce viral production effectively at concentrations that were non-toxic for Vero cells. Molecular modeling assays predicted low toxicity risk and good oral bioavailability of the substances in humans. One of the molecules, selected for further study, demonstrated a strong anti-MAYV effect at early stages of replication, as it protected pre-treated cells and also during the late stages, affecting virus morphogenesis. This study is the first to demonstrate the antiviral effect of thienopyridine derivatives on MAYV replication in vitro, suggesting the potential application of these substances as antiviral molecules against alphaviruses. Additional in vivo research will be needed to expand the putative therapeutic applications.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239459,"idioma_id":5,"titulo":"La Imagen en Disputa. Cronistas Barriales. Producir desde los barrios","resumen":"El proyecto de extensión ?Cronistas Barriales? de la Universidad Nacional de Quilmes tiene como obje-tivo capacitar a jóvenes de distintos barrios de la región en lenguaje, producción y posproducción infor-mativa audiovisual, con el fin de desarrollar un noticiero interbarrial realizado por jóvenes de la periferia del área metropolitana de Buenos Aires. Las  temáticas  del  noticiero  se  proponen  de  acuerdo  a  las  necesidades  informativas  de  la  cotidianidad  territorial en la cual se inserta el proyecto, posicionando a los y las jóvenes participantes en un rol activo y crítico frente a la realidad comunicacional","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239460,"idioma_id":5,"titulo":"Actividad reproductiva del salmón (Pseudopercis semifasciata) en aguas costeras de la provincia de Buenos Aires. Resultados de muestreos de desembarque del puerto de Quequén\/ Necochea años 2012, 2013 y 2014","resumen":"Se analizó la biología reproductiva del salmón de mar, Pseudopercis semifasciata, en aguas costeras bonaerenses cercanas al puerto de Quequén \/ Necochea. El material provino de muestreos de desembarque realizados por el INIDEP durante los años 2012, 2013 y 2014. A partir del estudio de los estadios de madurez gonadal se determinó que la época reproductiva de esta especie en el área se extiende desde agosto a febrero, evidenciado por un marcado aumento en el Índice gonadosomático y debido a la presencia de hembras en puesta o con folículos postovulatorios (indicadores de desoves recientes). La fecundidad parcial mostró una relación positiva con la talla y con el peso de las hembras libre de ovarios, el valor medio fue de 93.483 ovocitos hidratados. La fecundidad relativa varió entre 18 y 51 ovocitos hidratados por gramo de hembra (libre de ovarios) y mostró una relación lineal negativa con la talla y el peso de las hembras. El peso seco, y diámetro de los ovocitos hidratados y de la gota oleosa no presentaron relaciones significativas con las características maternas. Los mayores desembarques se produjeron en los meses de marzo, septiembre y octubre, coincidiendo estos dos últimos con el momento de mayor actividad reproductiva de la especie.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239461,"idioma_id":4,"titulo":"Reproductive potential of pagrus pagrus (Perciformes: Sparidae) in coastal waters of buenos aires province (argentina) and Uruguay (34&ordm;-39&ordm;S)","resumen":"The reproductive potential of red porgy in coastal waters of Buenos Aires Province (Argentina) and Uruguay (34º-39ºS) was studied by means of a macroscopic and histological analysis of the gonads. Length and age at first maturity were determined, and fecundity, spawning frequency and egg quality were estimated. The spawning season extended from spring through summer between October and January with a peak of spawning in December. Length and age at maturity for sexes combined was 24.5 cm TL and 1.54 years, respectively. Batch fecundity ranged from 6,974 (25 cm TL) to 110,725 (39 cm TL) hydrated oocytes and showed significant linear relationships with total length and ovary-free weight. Relative fecundity ranged from 16 to 172 oocytes per female gram (ovary free). Spawning frequency was 58.5% during January 2011, indicating that females spawned once every 1-2 days at the peak of the spawning season. The life history of red porgy in Argentina and Uruguay was characterized by a young age at first maturity and partial, almost daily, spawning in a bounded time period, a life history strategy that would facilitate population expansion or colonization of new areas, and high population recovery rates or growth (r).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239462,"idioma_id":4,"titulo":"Effects of skipped spawning on the reproductive potential of Argentine hake (Merluccius hubbsi)","resumen":"We analyzed the effect of skipped spawning on the estimates of length and age at maturity and on the reproductive potential of Argentine hake (Merluccius hubbsi) from the Patagonian stock during the spawning peaks between 2005 and 2013. The length at first maturity increased by 2?3 cm in total length (TL), and the age at maturity increased by 0.27?0.88 years when the proportion of females that would skip spawning was incorporated in the relationships. In addition, the slopes of the models decreased, suggesting that all individuals reach sexual maturity at a greater size and age than those estimated with the traditional criterion for maturity, which does not consider skipped spawning because fish in the resting stage are classified as mature. The reduction in egg production caused by skipped spawning ranged between 3.56% and 12.12%, when we used the maturity models with age data, or between 2.70% and 6.80%, when we used the models with TL data. Females that would skip spawning were mainly specimens with sizes between 40 and 50 cm TL, and most belonged to the age class of 3-year-old fish.&#8195;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239463,"idioma_id":5,"titulo":"El abordaje del Holocausto desde la trama educativa: consideraciones sobre la construcción de una política de educación y memoria","resumen":"El presente artículo se propone reflexionar sobre la construcción de las políticas de educación y memoria desarrolladas en Argentina entre 2005 - 2015 desde el Ministerio de Educación de Nación, a través del Programa Educación y Memoria. Particularmente las que tuvieron eje en la enseñanza del Holocausto y los Genocidios en el siglo XX. Presentamos algunos problemas y desafíos que implicaron forjar, junto a otros tópicos, un horizonte de inclusión de la enseñanza de temas de historia reciente y memoria como parte de una política pública. Partimos de pensar cómo se incluyó el Holocausto en la agenda educativa y cómo se construyó un problema pedagógico en torno a su enseñanza. Para esto nos detenemos en dos líneas de políticas centrales: la producción de materiales educativos y la formación docente. ¿Por qué el Estado produjo sus propios materiales educativos para la enseñanza del Holocausto? ¿Qué mecanismos de producción involucraron? ¿Qué objetivos perseguían? ¿Qué dilemas, problemas o preguntas atravesaron su proceso de producción? ¿Cómo fueron los espacios de formación docentes? ¿Qué inquietudes y preguntas aparecieron en la formulación de propuestas y en el trabajo con los docentes? ¿Qué sucedió en el encuentro con estudiantes? ¿Qué aspectos de la pedagogía de la memoria sirvieron para pensar tanto los materiales como los encuentros de formación con docentes?","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239465,"idioma_id":4,"titulo":"Excitation-emission fluorescence-kinetic data obtained by Fenton degradation. Determination of heavy-polycyclic aromatic hydrocarbons by four-way parallel factor analysis","resumen":"For the first time, a simple and environmentally friendly third-order\/four-way calibration was applied for thesimultaneous determination of five heavy-polycyclic aromatic hydrocarbons (PAHs) in interfering environments.The kinetic evolution of the Fenton degradation of benzo[a]pyrene, dibenz[a,h]anthracene, benzo[b]fluoranthene, benzo[k]fluoranthene and benz[a]anthracene was followed by recording full excitation-emissionfluorescence matrices (EEFMs) of the samples at different reaction times, obtaining third-order EEFM-kinetic(EEFM-K) data. The sensitivity of the method was increased by carrying out the reaction in the presence ofmethyl-&#946;-cyclodextrin. The four-way parallel factor (PARAFAC) algorithm, which was used for data processing,exploits the second-order advantage, allowing analyte concentrations to be estimated even in the presence of anuncalibrated fluorescent background. The clear superiority of the applied approach in comparison with secondorder\/three-waycalibration performed with unreacting EEFMs is demonstrated, using two sets of samples withforeign compounds with particular spectral profiles. In one of the latter sets, the existence of a third-orderadvantage was explored and discussed. The feasibility to directly determine parts-per-trillion concentrationlevels of PAHs after a very simple solid-phase extraction with C18 membranes is established with natural watersamples containing uncalibrated constituents.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239466,"idioma_id":4,"titulo":"Defeasible argumentation over relational databases","resumen":"Defeasible argumentation has been applied successfully in several real-world domains in which it is necessary to handle incomplete and contradictory information. In recent years, there have been interesting attempts to carry out argumentation processes supported by massive repositories developing argumentative reasoning applications. One of such efforts builds arguments by retrieving information from relational databases using the DBI-DeLP framework; this article presents eDBI-DeLP, which extends the original DBI-DeLP framework by providing two novel aspects which refine the interaction between DeLP programs and relational databases. First, we expand the expressiveness of dbi-delp programs by providing ways of controlling how the information in databases is recovered; this is done by introducing filters that enable an improved fine-grained control on the argumentation processes which become useful in applications, providing the semantics and the implementation of such filters. Second, we introduce an argument comparison criterion which can be adjusted at the level of literals to model particular features such as credibility and topic expertise, among others. These new tools can be particularly useful in environments such as medical diagnosis expert systems, decision support systems, or recommender systems based on argumentation, where datasets are often provided in the form of relational databases.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239467,"idioma_id":4,"titulo":"Relationship between morphological abnormalities in commercial bull frozen semen doses and conception rate","resumen":"Commercial doses of frozen bull semen for artificial insemination may have a certain percentage of morphological defects, despite being subject to prior selection. The aims of this study were to determine the prevalence of morphological abnormalities in commercial doses (n=55, r=2) of dairy and beef bulls, from AI centers and to determine the possible existence of differences between them, regarding the percentage of abnormal sperm. At least 200 sperm per sample were evaluated using Bengal Rose stain (3 % m\/v) and light microscopy (X 1000 magnification). The mean percentage of abnormal sperm samples from dairy breeds was 7.19% ± 4.91% and from beef breeds was 15.83% ± 9.28%. Significant differences between biotypes were found in the proportion of abnormal sperm, abnormal heads and abnormal midpieces; it could be due to different selection pressure. It was observed that the percentage of abnormal sperm was not a good fertility level predictor for the commercial samples of frozen bovine semen used in this study. In both biotypes, the midpiece abnormalities were the most frequent, mainly its distal flexion (compensable defect). This could be as a result of the effects of freezing and thawing on sperm.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239468,"idioma_id":5,"titulo":"Migraci&oacute;n peruana, trabajo en la construcci&oacute;n y producci&oacute;n del espacio en la Ciudad de C&oacute;rdoba, Argentina","resumen":"Este artículo se propone indagar en la articulación entre las trayectorias laborales en la construcción de varones peruanos en la ciudad de Córdoba (Argentina) y las formas de producción de los espacios donde se desenvuelve su vida cotidiana. En base a un trabajo de campo cualitativo sostenido en el tiempo en un barrio localizado en la periferia de esa ciudad, este estudio muestra el modo en que determinadas inserciones laborales funcionan como recursos estratégicos con los que cuentan las familias migrantes en pos de sostener su proyecto migratorio, asegurar su permanencia en el lugar de destino y resolver el derecho a la ciudad a través de la producción del espacio. En particular, los recursos que se obtienen a partir del trabajo en la construcción, habilitan diversas estrategias de reproducción de la vida tanto familiar como comunitaria en el marco de una ciudad cada vez más desigual.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239473,"idioma_id":4,"titulo":"Powered grape seeds (PGS) as an alternative biosorbent to remove pharmaceutical dyes from aqueous solutions","resumen":"An alternative, low-cost and efficient biosorbent, powdered grape seeds (PGS), was prepared from wastes of a wine industry, and used to remove brilliant blue (BB) and amaranth red (AR) dyes from aqueous solutions. The biosorbent was properly characterized before and after the biosorption operation. The potential of PGS to remove BB and AR dyes was investigated thought kinetic, isothermand thermodynamic studies. The biosorption of BB and AR was favored at pH 1.0 using biosorbent dosage of 0.500 g\/L, being attained more than 85% of removal percentage. For BB and AR dyes, pseudo-second order and Elovich models were able to explain the biosorption kinetic. The biosorption equilibrium of BB on PGS was well represented by the Langmuir model, while for AR, the Sips model was the most adequate. The maximum biosorption capacities were 599.5 and 94.2 mg\/g for BB and AR, respectively. The biosorption of BB and AR on PGS was a spontaneous,favorable and endothermic process. These findings indicated that PGS is a low-cost and efficient biosorbent, which can be used to treat dye containing waters.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239479,"idioma_id":4,"titulo":"Cooperative Behavior of Fluoroquinolone Combinations against Escherichia coli and Staphylococcus aureus","resumen":"The effects of different combinations of ciprofloxacin (CIP) and norfloxacin (NOR) against Escherichiacoli and Staphylococcus aureus were studied using checkerboard, fractional inhibitory concentration(FIC) and time?kill analysis methods. Results obtained by the checkerboard method showed that themore effectives combinations against Escherichia coli were 0.0009 &#956;g\/mL CIP0.0312 &#956;g\/mL NOR and0.0037 &#956;g\/mL CIP0.0075 &#956;g\/mL NOR with a FIC index of 0.62. For Staphylococcus aureus, the combinationof 0.0625 &#956;g\/mL CIP0.2500 &#956;g\/mL NOR showed a synergistic effect, with a FIC index of 0.50. The resultsof the time?kill method demonstrated either indifference or additivity of the combinations 0.0009 &#956;g\/mLCIP0.0312 &#956;g\/mL NOR, 0.0018 &#956;g\/mL CIP0.0312 &#956;g\/mL NOR, 0.0037 &#956;g\/mL CIP0.0075 &#956;g\/mL NORand 0.0037 &#956;g\/mL CIP0.0156 &#956;g\/mL NOR at 24 h against E. coli. The combination 0.0037 &#956;g\/mLCIP0.0312 &#956;g\/mL NOR showed synergistic activity. All the analyzed combinations evidenced bactericidaleffects at 4 h. The combinations 0.0625 &#956;g\/mL CIP0.2500 &#956;g\/mL NOR and 0.0625 &#956;g\/mL CIP0.0625 &#956;g\/mLNOR showed indifference or additivity against S. aureus. None of them generated bactericidal effect at 4 h.Moreover, this last equimolecular combination (equivalent to 1\/4 minimum inhibitory concentration (MIC)CIP1\/16 MIC NOR) generated higher reduction of nitro blue tetrazolium than drugs alone. By anotherway, combinations not equimolecular of CIP and NOR assayed, generated less levels of reactive oxygen species(ROS) than the components alone.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239480,"idioma_id":4,"titulo":"Lead selection of antiparasitic compounds from a focused library of benzenesulfonyl derivatives of heterocycles","resumen":"A library of 89 synthetic benzenesulfonyl derivatives of heterocycles with drug-like properties wasassayed for in vitro antiparasitic activity and the results were added to our previously reported derivativesfor a comprehensive SAR evaluation. Four compounds showed an IC50 between 0.25 and 3 lMagainst Leishmania donovani and low cytotoxicity. Compound G{16} (1-(2,3,5,6-tetramethylphenylsulfonyl)-2-methylindoline), was particularly interesting with an IC50 similar to the reference drug miltefosine.Seven compounds showed an IC50 below 6 mM against Trypanosoma cruzi, and three of them (E{3}, E{9} and G{3}) were identified as lead scaffolds for further optimization based on their activity-toxicityprofile. Two promising structures (B{15} and G{15}) showed moderate inhibitory activity againstPlasmodium falciparum. In general, the presence of a benzenesulfonyl moiety improves the antiparasiticactivity of the heterocycles included in this study (with the exception of Trypanosoma brucei rhodesiense),validating the criteria used in the selection of the privileged structures and diversification used to generatethis library. SAR analysis showed that the presence of lipophilic and electron withdrawing groupswere favorable for the antiparasitic activity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239481,"idioma_id":4,"titulo":"Nebulizing novel multifunctional nanovesicles: the impact of macrophage-targeted-pH-sensitive archaeosomes on pulmonary surfactant","resumen":"In this work, a NE-U22 vibrating mesh Omron nebulizer was used to deliver Lissamine? rhodamine B 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine triethylammonium salt (Rh-PE) and 8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt (HPTS)\/ p-xylene-bis-pyridinium bromide (DPX) double labelled macrophage-targeted pH-sensitive archaeosomes (ApH, 174 ?b 48 nm, - 30 ?b 13 mV unilamellar nanovesicles made of dioleoyl-sn-glycero-3-phosphoethanolamine: [total polar archaeolipids from the hyperhalophile archaebacteria Halorubrum tebenquichense]: cholesterylhemisuccinate 4.2:2.8:3 w:w:w) - on J774A.1 cells covered by Prosurf pulmonary surfactant (PS) monolayer at or below the equilibrium surface pressure . The uptake and cytoplasmic drug release from ApH were assessed by flow cytometry of Rh-PE and HPTS fluorescence respectively. Despite of being soft matter submitted to dismantling interactions of shear stress of nebulization and contact with surfactant barrier, at least a fraction of nebulized ApH was found to be stable enough to execute higher cytoplasmic delivery than archaeolipids lacking vesicles. Nebulized ApH increased the PS tensioactivity below e only, out of the physiological range. This would mean that in vivo, changes in lung surfactant function induced by nebulized nanovesicles, is poorly likely to occur. The cytoplasmic delivery from ApH slightly decreased across monolayers at , suggesting that nanovesicles crossed the PS in a fashion inversely related to monolayer compression. Laurdan Generalized Polarization and Fluorescence Anisotropy were used to reveal that nanovesicles neither depleted B and C proteins of the PS, not increased its fluidity. Together with the feasibility of cytoplasmic drug delivery upon nebulization, our results suggest that ApH are structurally unique nanovesicles that would not induce biophysical changes leading to PS inactivation, and open the door to future deeper translational studies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239483,"idioma_id":5,"titulo":"Entre los fundamentos técnicos y los tamices ideológicos: reflexiones en torno a la misión principal de las Fuerzas Armadas en la Argentina","resumen":"The primary mission of the Armed Forces is again under debate in Argentina. Current discussion is not related to the main topic of the 1980s, which was the military subordination to the civil authorities after decades of political involvement. Nowadays, the military are completely subordinated to the democratic institutions. However, the basic legal framework of the National Defense System is at a crossroads. Certain political and academic sectors highlight the need to alter the current normative framework in order to enable the military to play a role against the new global threats such as drug trafficking and terrorism. This article sets out a number of political and technical reasons against this position.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239484,"idioma_id":5,"titulo":"Acompañamiento en el ingreso a la universidad: las tutorías en ingeniería","resumen":"El ingreso a la universidad implica para el alumno una situación nueva, en la que, normalmente, se enfrenta con las herramientas construidas a lo largo de su trayectoria tanto escolar como extraescolar y conforman una nueva manera de aprender. Esta ?forma de aprender? se pone en tensión con las exigencias académicas propias del campo disciplinar de la Ingeniería y\/o Licenciatura en Sistemas: relación de conceptos abstractos, resolución de situaciones problemáticas, desarrollo de algoritmos, entre otras. En este trabajo se presenta una sistematización de una experiencia desde el área de Tutorías que se llevó a cabo con los estudiantes ingresantes de las carreras de la Escuela de Tecnologías de la Información y de las Comunicaciones de la Universidad Nacional de Chilecito (UNdeC) en Argentina durante el primer cuatrimestre del periodo académico 2016. Las acciones objeto de análisis en esta presentación son: a) el curso de ingreso como una reflexión de la transición de la escuela a la universidad; b) el cursado a partir del trabajo colaborativo entre asignaturas y la incorporación del tutor par; y, c) el cierre del cuatrimestre con una evaluación para conocer los logros y obstáculos de los ingresantes. Los resultados visibilizan que los procesos de estudio de los aprendices de 1er. año se vinculan ampliamente con las prácticas de la secundaria. Estas condiciones que los alumnos informan y que han sido vividas en su 1er. año universitario son condiciones del ingresante universitario que requieren ser trabajadas y atendidas de forma integrada.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239485,"idioma_id":5,"titulo":"Introducción a la Vida Universitaria: una experiencia de articulación  en el ingreso","resumen":"El ingreso es objeto de diversas investigaciones y reflexiones en los escenarios universitarios (Ezcura, 2011; Gluz, 2011; Pierella, 2014; entre otros). Los estudiosos coinciden que es un momento vital para los estudiantes porque significa transitar, elegir y comprender las dinámicas propias de la universidad. Asimismo, en la Universidad son conocidas las quejas que existen respecto de las pocas competencias, habilidades y el exceso de deficiencias o dificultades de los estudiantes en el primer año de la universidad bien porque carecen de un conocimiento de áreas como la matemática, física o química o bien porque los estudiantes no saben ni siquiera, en palabras de los docentes, leer y escribir los textos de las disciplinas. Ahora bien, pensar la lectura y escritura de esta manera nos invisibiliza la complejidad de leer y escribir en la Universidad, que en palabras de Carlino (2005) significa acceder a una nueva cultura académica. En este artículo el propósito es narrar la experiencia de escritura del Cuadernillo de la asignatura Introducción a la Vida Universitaria del Curso de Ingreso en la Universidad Nacional de Chilecito y mostrar cómo planificamos el dictado de esta asignatura en el ingreso con los equipos docentes. Si bien no es un trabajo acabado, creemos que nos brinda una línea de reflexión sobre las prácticas inherentes al ingreso que posibilitan articular con el primer año y promueven la permanencia y pertenencia universitarias.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239486,"idioma_id":5,"titulo":"La caracterización del ingresante: una oportunidad para favorecer la  inclusión en la universidad","resumen":"¿Es el ingreso a la universidad una oportunidad para pensar la inclusión?, ¿cuál es el aporte de una caracterización de los estudiantes para el ingreso?, ¿qué caracteriza a los estudiantes ingresantes de la UNdeC (Universidad Nacional de Chilecito)? Estas preguntas son objeto de revisión en este artículo que se plantea pensar la caracterización de los ingresantes como una posibilidad de inclusión e ingreso articulados en el primer año de la universidad. El ingreso es un asiduo tema de discusión en la agenda de las universidades porque se vincula con la masificación en la educación superior (Ezcurra, 2011) y además porque se relaciona con la equidad y calidad en la universidad. La autora sostiene que en América Latina ese avance es más intenso porque existe una ?desigualdad intrarregional? muy acentuada en cuanto a los grados de masificación y la tasa de egresados lo que se hipotetiza deviene en un alto abandono de los estudios superiores. Pensar la inclusión desvinculada de la masificación dentro de las instituciones no tiene cabida en la actualidad, sin embargo, en universidades ubicadas en pequeñas ciudades no es la masificación el punto de partida, sino la discusión sobre posibilidad de brindar a los estudiantes la oferta universitaria como una oportunidad para mejorar la calidad de vida de ellos y sus familias. En otras palabras, resignifica el papel de las universidades en sectores con escasas ofertas culturales, académicas, económicas y sociales. Se convierte la universidad en el espacio de encuentro para acceder y apropiarse de formas de conocer y ser a las que no tendrían acceso si no ingresaran a la universidad. En este artículo ponemos en tensión justamente cómo las características de los ingresantes a la Universidad Nacional de Chilecito no pueden ignorarse, por cuanto informan sobre unas trayectorias e historias de vida importantes para la reconstrucción del ingreso y la transición de la secundaria a la universidad. No son datos que pueden descontextualizarse de un escenario en el que lo público, irrestricto y situado conviven en el día a día en la articulación de acciones que apunten a la permanencia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239488,"idioma_id":5,"titulo":"¿Cuáles son los métodos preferidos para el modelado de preferencias? - Estudio de la comparación entre pares frente a la valoración directa","resumen":"En los sistemas de soporte de decisión generalmente se incluyen modelos de decisión que deben contener un sencillo e intuitivo método para la expresión de las preferencias de los decisores. Los problemas de decisión se dividen en dos grandes grupos: los que se basan en preferencias y los que se basan en similitud. La modelización de las preferencias del decisor constituye una etapa indispensable en la construcción de modelos utilizados en teoría de la decisión, investigación operativa, economía, etc. Dos métodos habitualmente utilizados para recoger las opiniones de los expertos son la matriz de comparación entre pares y la tupla de valoración directa. Para el estudio realizado se ha decidido utilizar la técnica de investigación por encuesta y para la recolección de datos se han utilizado cuestionarios. Se realizó un estudio poblacional con alumnos de la Licenciatura en Sistemas de Información de la Facultad de Ciencias Exactas y Naturales y Agrimensura de la Universidad Nacional del Nordeste, de la Ingeniería en Sistemas de Información de la Facultad Regional Resistencia de la Universidad Tecnológica Nacional y de la Tecnicatura en Análisis de Sistemas del Instituto Superior de Formación Docente de Curuzú Cuatiá, habiéndose utilizado un muestreo no probabilístico. Se realizó una comparación entre dos métodos habitualmente utilizados para la expresión de las preferencias de los decisores, el de matriz de comparación entre pares (CEP) y el de tuplas de valoración directa (TVD). Se utilizaron ambos métodos en problemas de creciente número de alternativas (complejidad creciente), se evaluó cada método por separado y luego se compararon ambos métodos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239489,"idioma_id":5,"titulo":"Sobre biopolítica y agronegocios","resumen":"El trabajo estudia el proceso de expansión del modelo de agronegocios (agricultura capitalista en base a biotecnología) en el Cono Sur a partir de los conceptos de biopolítica y biopoder como una alternativa al convencional análisis productivista que se realiza generalmente dentro de las Ciencias Económicas. Por otro lado se revisa el rol que juega por omisión o complicidad el Estado en la expansión del capitalismo en el agro a partir de innovaciones biotecnológicas y los riesgos implícitos en este proceso.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239490,"idioma_id":5,"titulo":"Sobre Biopolítica y Agronegocios","resumen":"El trabajo estudia el proceso de expansión del modelo de agronegocios (agricultura capitalista en base a biotecnología) en el Cono Sur a partir de los conceptos de biopolítica y biopoder como una alternativa al convencional análisis productivista que se realiza generalmente dentro de las ciencias económicas. Por otro lado se revisa el rol que juega por omisión o complicidad el Estado en la expansión del capitalismo en el agro a partir de innovaciones biotecnológicas y los riesgos implícitos en este proceso.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239491,"idioma_id":4,"titulo":"Review of Neuroscience and Multilingualism, by Edna Andrews","resumen":"In a massively interconnected world, marked by constant political, educational, and recreational exchanges across cultures and nations, it is no surprise that multilingualism has become at least as prevalent as monolingualism (Grosjean, 1994 , 2013 ). Neither is it startling for this phenomenon to have entered theradar of neuroscience, as it entails various cognitive peculiarities of theoretical and translational interest (Bialystok, Abutalebi, Bak, Burke, & Kroll, 2016 ; Bialystok, Craik, & Luk, 2012 ). The ensuing research niche has grown dramatically in the last two decades, rekindling classical debates and prompting reflection on novel issues. Against this background, Neuroscience and Multilingualism addresses the challenge of offering a concise but diverse introduction to the topic.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239492,"idioma_id":4,"titulo":"A lesion model of envy and Schadenfreude: legal, deservingness and moral dimensions as revealed by neurodegeneration","resumen":"The study of moral emotions (i.e. Schadenfreude and envy) is critical to understand the ecological complexity of everyday interactions between cognitive, affective, and social cognition processes. Most previous studies in this area have used correlational imaging techniques and framed Schadenfreude and envy as unified and monolithic emotional domains. Here, we profit from a relevant neurodegeneration model to disentangle the brain regions engaged in three dimensions of Schadenfreude and envy: deservingness, morality, and legality. We tested a group of patients with behavioural variant frontotemporal dementia (bvFTD), patients with Alzheimer?s disease, as a contrastive neurodegeneration model, and healthy controls on a novel task highlighting each of these dimensions in scenarios eliciting Schadenfreude and envy. Compared with the Alzheimer?s disease and control groups, patients with bvFTD obtained significantly higher scores on all dimensions for both emotions. Correlational analyses revealed an association between envy and Schadenfreude scores and greater deficits in social cognition, inhibitory control, and behaviour disturbances in bvFTD patients. Brain anatomy findings (restricted to bvFTD and controls) confirmed the partially dissociable nature of the moral emotions? experiences and highlighted the importance of socio-moral brain areas in processing those emotions. In all subjects, an association emerged between Schadenfreude and the ventral striatum, and between envy and the anterior cingulate cortex. In addition, the results supported an association between scores for moral and legal transgression and the morphology of areas implicated in emotional appraisal, including the amygdala and the parahippocampus. By contrast, bvFTD patients exhibited a negative association between increased Schadenfreude and envy across dimensions and critical regions supporting social-value rewards and social-moral processes (dorsolateral prefrontal cortex, angular gyrus and precuneus). Together, this study provides lesion-based evidence for the multidimensional nature of the emotional experiences of envy and Schadenfreude. Our results offer new insights into the mechanisms subsuming complex emotions and moral cognition in neurodegeneration. Moreover, this study presents the exacerbation of envy and Schadenfreude as a new potential hallmark of bvFTD that could impact in diagnosis and progression.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239493,"idioma_id":4,"titulo":"Hormonal Modulation of Dendritic Cells Differentiation, Maturation and Function: Implications for the Initiation and Progress of Systemic Autoimmunity","resumen":"Hormonal homeostasis is crucial for keeping a competent and healthy immune function. Several hormones can modulate the function of various immune cells such as dendritic cells (DCs) by influencing the initiation of the immune response and the maintenance of peripheral tolerance to self-antigens. Hormones, such as estrogens, prolactin, progesterone and glucocorticoids may profoundly affect DCs differentiation, maturation and function leading to either a pro-inflammatory or an anti-inflammatory (or tolerogenic) phenotype. If not properly regulated, these processes can contribute to the pathogenesis of autoimmune disease. An unbalanced hormonal status may affect the production of pro-inflammatory cytokines, the expression of activating\/inhibitory receptors and co-stimulatory molecules on conventional and plasmacytoid DCs (pDCs), conferring susceptibility to develop autoimmunity. Estrogen receptor (ER)-&#945; signaling in conventional DCs can promote IFN-&#945; and IL-6 production and induce the expression of CD40, CD86 and MHCII molecules. Furthermore, estrogen modulates the pDCs response to Toll-like receptor ligands enhancing T cell priming. During lupus pathogenesis, ER-&#945; deficiency decreased the expression of MHC II on pDCs from the spleen. In contrast, estradiol administration to lupus-prone female mice increased the expression of co-stimulatory molecules, enhanced the immunogenicity and produced large amounts of IL-6, IL-12 and TNF-&#945; by bone marrow-derived DCs. These data suggest that estradiol\/ER signaling may play an active role during lupus pathology. Similarly, understanding hormonal modulation of DCs may favor the design of new therapeutic strategies based on autologous tolerogenic DCs transfer, especially in sex-biased systemic autoimmune diseases. In this review, we discuss recent data relative to the role of different hormones (estrogen, prolactin, progesterone and glucocorticoids) in DC function during systemic autoimmune pathogenesis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239494,"idioma_id":4,"titulo":"Chronic Infection of the Prostate by Chlamydia muridarum Is Accompanied by Local Inflammation and Pelvic Pain Development","resumen":"BACKGROUND: Chlamydia trachomatis urogenital infections are the leading cause of sexually transmitted bacterial infections. Although the prevalence of chlamydial infection is similar in men and women, current research is mainly focused on women, neglecting the study of male genital tract infections. We, therefore, investigated Chlamydia infection in the rodent male genital tract. MATERIALS AND METHODS: Male NOD and C57BL\/6 mice were inoculated in the meatus urethra with C. muridarum. Bacterial DNA, leukocyte infiltration of male genital tract tissues, pelvic pain, and Chlamydia-specific immune responses were analyzed at different time points. RESULTS AND CONCLUSIONS: The inoculation of C. muridarum in the meatus urethra of male mice resulted in an ascending and widely disseminated infection of the male genital tract. C. muridarum remained longer and with the highest bacterial burdens in the prostate, thus showing a special tropism for this organ. Infection caused leukocyte infiltration, mainly composed by neutrophils, and also induced early pelvic pain development that rapidly dropped and resolved as the infection became chronic. Bacterial load and leukocyte infiltration was observed in all prostate lobes, although dorsolateral prostate was the most affected lobe. Interestingly, immune responses induced by both mice strains were characterized by the production of high levels of IL-10 during early stages of the infection, with highest and sustained levels observed in NOD mice, which showed to be less efficient in clearing the infection. Chronic infection of the prostate accompanied by local inflammation and pelvic pain development described herein have important implications for the improvement of the diagnosis and for the design of new efficient therapies. Prostate 77:517?529, 2017. © 2017 Wiley Periodicals, Inc.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239495,"idioma_id":4,"titulo":"Analysis of the ichnogenus Herradurichnus in quartzites of the Balcarce Formation (Lower Silurian) from the Tandilia System of Argentina","resumen":"Herradurichnus Poiré &amp; del Valle, 1996 from the Balcarce Formation (lower Paleozoic of the Tandilia System, Argentina) is an enigmatic ichnogenus previously considered as problematic. In this paper, Herradurichnus is revised and key material from collections is redescribed together with other specimens documented in situ from outcrops and quarries. The diagnosis is emended to include its morphological variability. The revised Herradurichnus includes negative, epichnial, U-shaped, V-shaped and parabolic depressions. The specimens are horizontal, subhorizontal or oblique with respect to the bedding plane, and are recorded in fine-grained to very coarse-grained sandstones. Other characteristics are also described in detail. The holotype of Herradurichnus scagliai (Borrello, 1967) has been recovered. Material previously included in Crescentichnus Romano &amp; Whyte, 2015 is now reassigned to Herradurichnus. Xiphosurans and trilobites are disregarded as possible trace-makers of Herradurichnus. The producers were able to construct structures oriented with the convex side of the arch in an opposite sense to the main paleocurrents. This ichnogenus is now reappraised and found to range from the Cambrian to the Lower Silurian of Gondwana.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239498,"idioma_id":5,"titulo":"DETERMINACION DE LAS CONSTANTES HIDRICAS DE JUJUY Y SALTA A NIVEL DE ASOCIACION, PARA EL MONITOREO DEL AGUA EN EL SUELO.","resumen":"Unas de las principales causas de la variación de los rendimientos de los cultivos, es ladisponibilidad de agua en el suelo. A pesar de la importancia de la humedad del suelo para laestimación de los rendimientos, la determinación fiable de esta variable a escala regional, através de mediciones puntuales convencionales, es compleja. Entre la información necesariapara la modelización del agua en el suelo, están las precipitaciones, la evapotranspiración ylas constantes hidrológicas. La primera se la obtiene por mediciones de diferentes lugares,la segunda por estimaciones; mientras que al no disponer de mediciones de humedadedáfica in situ, las constantes hidrológicas del suelo se estiman a partir de datos de suspropiedades físicas. El objetivo del presente trabajo es determinar las constantes hidrológicascorrespondientes a las asociaciones de suelos para las provincias de Jujuy y Salta. Paraello se ha utilizado el software SPAW, que posee ecuaciones de pedotransferencia y losvalores de las propiedades físicas de los suelos. Las constantes hídricas estimadas a nivel deasociación, para las profundidades 30, 70, 100 cm y profundidad efectiva, expresan la granvariación edáfica que presentan los suelos en ambas provincias.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239503,"idioma_id":4,"titulo":"Deleterious Metabolic Effects of High Fructose Intake: The Preventive Effect of Lactobacillus kefiri Administration","resumen":"Modern lifestyle and diets have been associated with metabolic disorders and an imbalancein the normal gut microbiota.  Probiotics are widely known for their health bene&#64257;cial propertiestargeting the gut microbial ecosystem. The aim of our study was to evaluate the preventive effectof Lactobacillus ke&#64257;ri (L. ke&#64257;ri) administration in a fructose-rich diet (FRD) mice model. Mice wereprovided with tap water or fructose-added (20% w\/v) drinking water supplemented or not withL. ke&#64257;ri. Results showed that probiotic administration prevented weight gain and epidydimal adiposetissue (EAT) expansion, with partial reversion of the adipocyte hypertrophy developed by FRD.Moreover, the probiotic prevented the increase of plasma triglycerides and leptin, together with theliver triglyceride content. Leptin adipocyte secretion was also improved by L. ke&#64257;ri, being able torespond to an insulin stimulus. Glucose intolerance was partially prevented by L. ke&#64257;ri treatment(GTT) and local in&#64258;ammation (TNF&#945;; IL1&#946;; IL6 and INF&#947;) was completely inhibited in EAT. L. ke&#64257;risupplementation generated an impact on gut microbiota composition, changing Bacteroidetes andFirmicutes pro&#64257;les. Overall, our results indicate that the administration of probiotics prevents thedeleterious effects of FRD intake and should therefore be promoted to improve metabolic disorders.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239504,"idioma_id":4,"titulo":"Effects of Oral Administration of Silymarin in a Juvenile Murine Model of Non-alcoholic Steatohepatitis","resumen":"Abstract: The increasing prevalence of non-alcoholic fatty liver disease (NAFLD) in adolescents is challenging the global care system. No therapeutic strategies have been defined so far, and changes in  the  lifestyle  remain  the  only  alternative.  In  this  study,  we  assessed  the  protective  effects  of silymarin in a juvenile non-alcoholic steatohepatitis (NASH) model and the in vitro effects on fat-laden human hepatocytes. C57Bl\/6 mice were exposed to HFHC diet immediately after weaning. After eight weeks, animals showed histological signs of NASH. Silymarin was added to the HFHC diet, the treatment continued for additional 12 weeks and the effects on BMI, hepatomegaly, visceral fat, lipid profile, transaminases, HOMA-IR, steatosis, inflammation, fibrosis, oxidative stress, and apoptosis  were  determined.  The  switch  from  HFHC  to  control diet  was  used  to  mimic life style changes.  In  vitro  experiments  were  performed  in  parallel  in  human  hepatocytes.  HFHC  diet supplemented  with  silymarin  showed  a  significant  improvement  in  glycemia,  visceral  fat,  lipid profile,  and  liver  fibrosis.  Moreover,  it  reduced  (both  in  vitro  and  in  vivo)  ALT,  hepatic inflammation,  oxidative  stress,  and  apoptosis.  Lifestyle  changes  restored  the  control  group parameters. The data presented show the beneficial effects of the oral administration of silymarin in the absence of changes in the dietary habits in a juvenile model of NASH.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239506,"idioma_id":4,"titulo":"Obstetric Disorders in the ICU","resumen":"Pregnant and postpartum patients represent a challenge to critical care physicians, as two patients in one have to be cared for and because specific obstetric disorders, not universally covered in formal critical care training, need to be managed. Pregnancy also alters physiologic norms, so that the critical care physician may either fail to recognize a value as abnormal in pregnancy or mistakenly identify as abnormal a value within the normal range for a pregnant woman. In this article, we will review the most frequent obstetric causes of admission of pregnant\/postpartum patients to the intensive care unit (hypertensive disease of pregnancy, obstetric hemorrhage, and obstetric sepsis) along with their diagnostic criteria, clinical presentation, and recommended treatment. We will also cover some specific, although less frequent, obstetric disorders, such as acute fatty liver of pregnancy, peripartum cardiomyopathy, and amniotic fluid embolism. Our primary aim is to improve quality of care for these types of patients.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239508,"idioma_id":4,"titulo":"A New Teaching Laboratory Experiment to Address the Effect of pH on  Solubility","resumen":"This paper presents a teaching experience involving an experiment based on the potentiostatic and electrochemical titration of a silver acetate solution with sodium hydroxide, a chemical system where at least three chemical equilibria are involved. It is known that natural samples are inherently complex, and several different chemical equilibria are simultaneously present. That is why we believe the understanding of complex systems is essential for carrying out chemical analysis. Solubility of many compounds is highly dependent on pH and many of the exercises in the inorganic chemistry classroom are focused on calculating the solubility of different species at different pHs, most of the times using speciation coefficients. However, the dependence of solubility on pH is usually analyzed in a point by point basis. This experiment, which only requires equipment usually available in any general chemistry teaching laboratory, allows students to analyze both a complex system and the dynamic nature of solubility when pH changes continuously in time. It gives them the possibility to reach a broader understanding of simultaneous chemical equilibria. Thus, we consider it to be an excellent complement to typical chemistry exercises.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239509,"idioma_id":5,"titulo":"Escenario actual de la normativa contable en Argentina. Opciones para Entes Pequeños y Medianos","resumen":".","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239516,"idioma_id":5,"titulo":"Merleau-Ponty, Foucault y el problema del conocimiento como condicionado","resumen":"Dialogando con el intento de Philippe Sabot (2013) de mostrar la cercanía de -por un lado- la reconstrucción foucaultiana sobre el  ?hombre? como ?duplicado empírico-trascendental? y -por otro lado- el problema de la dualidad de visiones sobre la cuestión antropológica tal como fue planteado por Merleau-Ponty en su curso sobre Las ciencias humanas y la fenomenología, intentaremos sacar a la luz de manera más ajustada cuáles son las preocupaciones epistemológicas específicas que guían la problematización merleaupontyana. Según señalaremos, el ?problema del hombre? tal como aparece en este curso no es, como en Foucault, el que surge a partir de un conocimiento empírico susceptible de ser elevado al rol de reflexión trascendental sobre las condiciones del conocimiento, sino que, a la inversa, se suscita en virtud de que las investigaciones empíricas sobre el hombre lo presentan, de modo paradójico, como una conciencia causalmente condicionada incapaz de nada que pudiéramos llamar ?conocimiento?. A continuación, buscaremos reconstruir las premisas en las que se basa esta argumentación merleaupontyana, lo que nos llevará a poner de manifiesto que su rechazo del ?psicologismo?, el ?sociologismo? y el ?historicismo? se conecta con la exigencia de que la conciencia pueda ejercer algún tipo de control epistémico sobre sus tomas de posición. Sobre la base de este resultado, señalaremos, por último, que el problema ?historicista? tal como aparece en Merleau-Ponty no es reductible a la forma de ?relativismo histórico? que, según Revel (2015), Foucault logra evitar.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239517,"idioma_id":5,"titulo":"La respuesta merleaupontyana a la ?inducción pesimista? como posible complemento de su polémica contra el escepticismo","resumen":"Intentaremos completar el análisis de la relación entre Merleau-Ponty y distintas posiciones escépticas -típicamente restringido a textos más ?canónicos?- a partir de su conferencia sobre Le primat de la perception. El fenomenólogo argumenta allí contra la ?inducción pesimista? según la cual podemos, a la luz de la refutación de las hipótesis científicas pasadas, prever que las actuales son también falsas: invirtiendo la conclusión de esta inducción, afirma que las transformaciones de nuestro conocimiento son un proceso autocorrectivo, tal que ninguna hipótesis es abandonada sino en la medida en que otra aparece como mejor. Esto nos hará problematizar la noción de refutación científica en Merleau-Ponty, quien ofrece como modelo del progreso epistémico la mutua sustitución (?espontánea?) de creencias perceptivas, que no involucra la consideración consciente de criterios racionales. Según señalaremos, este punto de partida no puede extrapolarse al caso de hipótesis sopesadas según sus respectivas virtudes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239526,"idioma_id":5,"titulo":"Duplicado empírico-trascendental? y ?escatología?: una vez más sobre las críticas de Foucault a Merleau-Ponty","resumen":"En este artículo intentaremos un análisis crítico de la célebre crítica de la fenomenología merleaupontyana en términos de una presunta oscilación entre ?positivismo? y ?escatología?, por medio de un diálogo con algunas de las interpretaciones previas de este debate. Como intentaremos demostrar, atribuir a Merleau-Ponty una reducción ?positivista? de la epistemología equivaldría a pasar por alto su insistencia en que nos apartemos de la autocomprensión que las ciencias empíricas ofrecen de sus propios resultados; esto es, pasar por alto sus objeciones fenomenológicas a los marcos ontológicos ingenuos del ?pensamiento objetivo?. Más aun, según argumentaremos, si reconstruimos el presunto ?positivismo? de Merleau-Ponty en términos de una ?verdad reducida a lo empírico?, esta lectura solo sería sostenible sobre la base de comprender la ?experiencia vivida?, analizada por el fenomenólogo francés, como si se tratase meramente de un punto de partida genético, empírico, y no reconocer la relación epistémica que, de acuerdo al fenomenólogo, existe entre tal ?experiencia vivida? y las descripciones en tercera persona ofrecidas por la ciencia. En cuanto al cargo de ?escatología?, aparentemente aplicado al fenomenólogo en virtud de sus deudas al pensamiento marxista, intentaremos probar que (sea que se lo comprenda en un sentido estrictamente epistemológico, o en conexión con una presunta adhesión merleaupontyana a cierta filosofía de la historia), se demuestra insostenible una vez que tomamos en consideración el carácter matizado de su aceptación de ciertos aspectos del materialismo histórico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239527,"idioma_id":4,"titulo":"Nutraceutical emulsion containing valproic acid (NE-VPA): a drug delivery system for reversion of seizures in zebrafish larvae epilepsy model","resumen":"Valproic acid (VPA) is an antiepileptic drug, which is currently used in neurodegenerative diseases. However, a high dose is required to obtain a therapeutic effect. Long-chain polyunsaturated fatty acids (PUFAs), such as omega 3 and omega 6, are efficient complements in treatments for neurological diseases. Previous studies have reported that a dietary supplement containing PUFAs together with the administration of antiepileptic drugs significantly reduces the frequency of seizures. Based on this, the main goal of this work was to obtain a complex based on VPA encapsulation in an oil\/water (o\/w) nutraceutical emulsion (NE) enriched with PUFAs for oral administration. Besides, encapsulation of VPA might reduce its dose and increase its therapeutic effect. In order to study its effect, we used a zebrafish larvae model of induced epileptiform behavior with the proconvulsant drug pentylenetetrazol (PTZ). Results have shown that when 100&nbsp;&#956;M VPA and fatty acids were combined in the NE (NE-VPA), the epileptiform behavior of PTZ-treated zebrafish larvae decreased significantly. Additionally, morphological changes, hepatotoxicity, lethality and heart rate were studied. Despite the fact that a high dose of VPA exerted a cardiotoxic effect, this was no longer detected after addition of this drug in the NE. This treatment exerted a significant antiepileptic effect and did not result in highly toxic or lethal effects. In order to develop an improved pharmaceutical treatment, and considering that all the components used are FDA approved for consumption, the NE-VPA selected might be easily incorporated into clinical trials.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239528,"idioma_id":4,"titulo":"Effect of mixed pinning landscapes produced by 6&nbsp;MeV oxygen irradiation on the resulting critical current densities Jc in 1.3&nbsp;&micro;m thick GdBa 2 Cu 3 O 7- d coated conductors grown by co-evaporation","resumen":"We report the influence of crystalline defects introduced by 6 MeV 16O3+ irradiation on the critical current densities Jc and flux creep rates in 1.3 µm thick GdBa2Cu3O7- &#948; coated conductor produced by co-evaporation. Pristine films with pinning produced mainly by random nanoparticles with diameter close to 50 nm were irradiated with doses between 2 × 1013 cm&#8722;2 and 4 × 1014 cm&#8722;2. The irradiations were performed with the ion beam perpendicular to the surface of the samples. The Jc and the flux creep rates were analyzed for two magnetic field configurations: magnetic field applied parallel (H&#9553;c) and at 45° (H&#9553;45°) to the c-axis. The results show that at temperatures below 40 K the in-field Jc dependences can be significantly improved by irradiation. For doses of 1 × 1014 cm&#8722;2 the Jc values at &#956;0H = 5 T are doubled without affecting significantly the Jc at small fields. Analyzing the flux creep rates as function of the temperature in both magnetic field configurations, it can be observed that the irradiation suppresses the peak associated with double-kink relaxation and increases the flux creep rates at intermediate and high temperatures. Under 0.5 T, the flux relaxation for H&#8214;c and H||45° in pristine films presents characteristic glassy exponents &#956; = 1.63 and &#956; = 1.45, respectively. For samples irradiated with 1 × 1014 cm&#8722;2, these values drop to &#956; = 1.45 and &#956; = 1.24, respectively","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239529,"idioma_id":4,"titulo":"C5aR contributes to the weak Th1 profile induced by an outbreak strain of Mycobacterium tuberculosis","resumen":"C5a anaphylatoxin is a component of the complement system involved in the modulation of T-cell polarization. Herein we investigated whether C5a receptors, C5aR and C5L2, modulate the cytokine profiles induced by Mycobacterium tuberculosis (Mtb). We analyzed the impact of both receptors on T helper cell polarization induced by the multidrug resistant outbreak strain named M, which is a poor IFN-&#947; inducer compared with the laboratory strain H37Rv. To this aim, we first blocked C5aR or C5L2 of peripheral blood monocytes (Mo) from patients with tuberculosis and healthy donors, then we stimulated the Mo either with H37Rv or the M strain, and finally we analyzed cytokine profiles of Mo\/macrophages (M&#934;) and CD4+ T-cells. We found that: (i) Mtb modulated the expression of both C5a receptors, (ii) C5aR inhibited the expansion of CD4+IFN-&#947;+ lymphocytes stimulated by the M strain but not by H37Rv, (iii) both receptors modulated the Mo\/M&#934; cytokine expression induced by Mtb. We conclude that C5aR, but not C5L2, plays a role in T helper cell polarization induced by Mtb and that this effect is strain- and donor-dependent. We speculate that the epidemiologically successful M strain takes advantage of this C5aR-mediated inhibition of Th1 polarization to survive within the host.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239532,"idioma_id":5,"titulo":"La mediación tecnológica en el acompañamiento y la visualización del proceso de escritura","resumen":"El presente artículo describe los primeros resultados de una tesis de maestría que busca identificar prácticas de lectura y escritura mediadas por tecnología en el nivel superior. Se realizaron entrevistas en profundidad a docentes, observación de documentos y de entornos virtuales. Entre los motivos por los que los entrevistados justifican el uso de la tecnología, se destacan principalmente la motivación y el aprovechamiento del tiempo que ofrecen las TIC en general. Este artículo se enfoca en algunas características de la mediación tecnológica en el proceso de escritura, desde la perspectiva de los docentes entrevistados, en especial el acompañamiento durante el inicio y el avance del proceso de escritura y la posibilidad de visualizar el camino recorrido.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239533,"idioma_id":5,"titulo":"La presencia del otro como desafío de la escritura mediada por tecnología","resumen":"Este artículo deriva de la tesis ?La enseñanza de lectura y escritura mediadas por tecnología en la educación superior? de la Maestría en Procesos Educativos Mediados por Tecnologías de la Universidad Nacional de Córdoba, Argentina. Se sistematizan desafíos encontrados por los docentes en relación con actividades de escritura que requerían escribir con otros y para otros, compartir trabajos, negociar y crear escritos en forma conjunta. Se realizó un estudio cualitativo desde una lógica inductiva que buscó la generación de categorías de análisis que permitiesen conocer el fenómeno desde la descripción de prácticas concretas. Se utilizó el diseño de teoría fundamentada y, en consonancia con ello, el método comparativo constante y el muestreo teórico. Se entrevistaron 14 docentes, se observaron documentos y entornos virtuales. Los entrevistados expresaron que con la inclusión de las TIC en el trabajo del aula surgen ?o se visibilizan? desafíos específicos, entre los que mencionaron lograr que los estudiantes dialoguen, lleguen a acuerdos, colaboren o produzcan con otros y que sus trabajos sean visibles para el resto del grupo o para la comunidad. Exponerse, negociar y crear con otros son nuevas competencias que es necesario desarrollar junto con las propias de la escritura.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239534,"idioma_id":5,"titulo":"La casita de abriendo tranqueras","resumen":"Desde hace muchos años se viene implementando el Proyecto ?AbriendoTranqueras? como parte de las distintas acciones que la Facultad de Ciencias AgrariasUNRrealiza en materia de extensión universitaria. El mismo contempla una ampliagama de actividades que incluyen el uso de espacios diversos entre los que se encuentrael sector del campo correspondiente al Módulo de Fruticultura de la cátedra de CultivosIntensivos, Área Fruticultura.La complejidad que fue adquiriendo el proyecto en su implementación dejó demanifiesto la necesidad de contar con determinadas condiciones de trabajo, a fin derecibir la ambiciosa cantidad de alumnos y docentes de la escuela ?Joaquina Villarinode Soage? de la localidad de Zavalla. Se trata de los destinatarios, que constituyen ungrupo de más de 200 personas, entre niños y adultos, que en actividades programadassemanalmente en contacto con la tierra y la naturaleza, implementan tareas destinadas afortalecer la convivencia y el trabajo colaborativo.Para dar respuesta a las necesidades derivadas de la marcha del proyecto surgióla idea de contar con un salón de usos múltiples que permita el desarrollo de tareasacadémicas y que también posibilite el guardado de algunos elementos. En tal sentido,en un primer momento, se pensó en modificar la construcción que ya existía en el predioy adecuarla a las nuevas necesidades. Sin embargo pronto se pudo determinar que lascondiciones de la misma no lo permitían y que sería necesario realizar una nueva obra.Lo que parecía un impedimento pronto se transformó en una oportunidad.Hacia el año 2014 se comienza la planificación y ejecución de la obra. Se tratade un espacio de treinta metros cubiertos.La obra fue llevada a cabo en dos grandes momentos.Hoy, la construcción ha finalizado, faltando la instalación eléctrica y algunos otros detalles; como tareas de pintura, completar la mesada y la colocación de estanterías para ordenar las herramientas, entre otras.El desafío y las ganas de este grupo de docentes y no docentes por asumir el compromiso de poder sumar esta instalación a nuestra querida Facultad de Ciencias Agrarias de la UNR, Universidad pública, gratuita y laica, llega a su fin; tenemos ahora la satisfacción de la misión cumplida.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239537,"idioma_id":4,"titulo":"Evidence for a prokaryotic origin of intracellular corpuscles in the digestive gland of the queen conch Lobatus gigas (Linnaeus, 1758) (Gastropoda: Strombidae)","resumen":"Two types of pigmented intracellular bodies have been reported in the digestive glands of several caenogastropods, particularly in the families Ampullariidae (Architaenioglossa: Ampullarioidea), Strombidae and Struthiolariidae (Littorinimorpha: Stromboidea). Rounded corpuscles, which are usually light brown, are identified here as C corpuscles, while corpuscles that are oval, darker and larger are identified as K corpuscles. We studied both corpuscular types in Lobatus gigas (Strombidae) using (1) differential-interference contrastmicroscopy, (2) transmission electron microscopy, (3) in situ hybridization with a generalized cyanobacterial 16S rRNA probe and (4) autofluorescence before and after lysozyme digestion. Results indicated that C corpuscles were located in the basal regions of columnar cells and the intensity of their pigmentationand alcianophily (indicative of glycosaminoglycans) was variable. They showed an electrondense wall and contained abundant electron-dense clumps and irregularly arranged membranes, but no thylakoids or nuclei. Hybridization with the 16S rRNA probe varied from none to intense in C corpuscles, indicative of variations in the rRNA content during their life cycles. Their walls were sensitive to lysozyme digestion, which strongly suggests that peptidoglycans are an integral part of this structure. K corpuscles were located within pyramidal cells and were uniformly dark brown but variably alcianophilic. They showed multiple lamellae of moderate electron density, organized around one to three cores, each one containing one or several small spherical bodies. All K corpuscles hybridized with the 16S rRNA probe and were partly digested by lysozyme. Both C and K corpuscles showed red autofluorescence, which suggests the presence of chlorophyll-like pigments. It is concluded that C and K corpuscles in the digestive gland of L. gigas may be forms of a prokaryotic symbiont related to the Cyanobacteria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239541,"idioma_id":5,"titulo":"La casita de abriendo tranqueras","resumen":"Desde hace muchos años se viene implementando el Proyecto ?AbriendoTranqueras? como parte de las distintas acciones que la Facultad de Ciencias AgrariasUNRrealiza en materia de extensión universitaria. El mismo contempla una ampliagama de actividades que incluyen el uso de espacios diversos entre los que se encuentrael sector del campo correspondiente al Módulo de Fruticultura de la cátedra de CultivosIntensivos, Área Fruticultura.La complejidad que fue adquiriendo el proyecto en su implementación dejó demanifiesto la necesidad de contar con determinadas condiciones de trabajo, a fin derecibir la ambiciosa cantidad de alumnos y docentes de la escuela ?Joaquina Villarinode Soage? de la localidad de Zavalla. Se trata de los destinatarios, que constituyen ungrupo de más de 200 personas, entre niños y adultos, que en actividades programadassemanalmente en contacto con la tierra y la naturaleza, implementan tareas destinadas afortalecer la convivencia y el trabajo colaborativo.Para dar respuesta a las necesidades derivadas de la marcha del proyecto surgióla idea de contar con un salón de usos múltiples que permita el desarrollo de tareasacadémicas y que también posibilite el guardado de algunos elementos. En tal sentido,en un primer momento, se pensó en modificar la construcción que ya existía en el predioy adecuarla a las nuevas necesidades. Sin embargo pronto se pudo determinar que lascondiciones de la misma no lo permitían y que sería necesario realizar una nueva obra.Lo que parecía un impedimento pronto se transformó en una oportunidad.Hacia el año 2014 se comienza la planificación y ejecución de la obra. Se tratade un espacio de treinta metros cubiertos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239548,"idioma_id":4,"titulo":"PRRG4 function reveals that Robo trafficking is evolutionarily conserved","resumen":"Achieving a correct set of neuronal connections during development is key for a healthy functioningnervous system. Autism, which is characterised by impairments in social interaction,language, and range of interests, has been hypothesised to originate from defective synapticfunction and abnormal brain connectivity [1,2]. Moreover, genetic alterations such as the deficiencyin proline-rich carboxyglutamic acid protein 4 (PRRG4) have been associated withautistic features present in WAGR syndrome (Wilm´s tumour, aniridia, genitourinary anomaliesand ªmental retardationº). Therefore, understanding the genetic mechanisms underlyingthe assembly of brain circuits is likely to be essential for the design of new diagnostic tools andtherapeutic strategies for Autistic Spectrum Disorders (ASD). In this issue of PLOS Genetics,Justice et al. link genetic alterations and neural circuitry development, revealing a novel rolefor the PRRG4 as a regulator of Roundabout (Robo) receptor subcellular localization in thenervous system [3].","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239549,"idioma_id":5,"titulo":"Las ediciones de Pedro Lozano. Las reediciones y la construcción historiográfica de su figura durante los siglos XIX y XX","resumen":"La Compañía de Jesús alentó, desde su sede central en Roma,  la redacción de historias para registrar la vida y los hechos realizados por los primeros jesuitas. Por esto en todas las provincias se escribieron historias que debían narrar las tareas que la Orden realizaba en las zonas en las que actuaba. En este trabajo pretendemos concentrarnos en los momentos de edición y reedición de las cuatro obras históricas de Pedro Lozano, quien había sido designado historiogrphus provinciae de la Provincia del Paraguay en 1730: la Descripción del Chaco, la Historia de las revoluciones del Paraguay, la Historia de la conquista del Paraguay, Río de la Plata y Tucumán y la Historia de la Compañía de Jesús en la Provincia del Paraguay. Este trabajo tiene origen en nuestros estudios doctorales en los cuales analizamos la producción historiográfica de Pedro Lozano; de dicho trabajo, se desprende el presente estudio ya que creemos que las reediciones de sus obras durante los siglos XIX y XX contribuyeron a forjar la figura de Lozano como una de las fundantes de la historiografía colonial. Abordando este análisis desde una perspectiva que considera que los discursos jesuíticos se construyeron al asociar la realidad con los textos en los que fijó la misma, según modelos discursivos y delimitaciones intelectuales propios de cada situación de escritura. Por esto nos proponemos analizar el momento en que fueron editadas y reeditadas durante los siglos XVIII, XIX y XX las obras seleccionadas, para ver el sentido, la necesidad y su significancia en cada momento histórico de dichas ediciones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239550,"idioma_id":5,"titulo":"ÉTICA PROFESIONAL EN LA FORMACIÓN UNIVERSITARIA","resumen":"El presente trabajo se origina en las inquietudes que recogí como profesional docente de la cátedra de Práctica Profesional de Aplicación Jurídica de la carrera de Contador Público de la Facultad de Ciencias Económicas perteneciente a la UNER con relación a las siguientes situaciones problemáticas:?Atento a que los alumnos de práctica profesional de Aplicación Jurídica se encuentran a punto de egresar y, en consecuencia, ejercer la profesión, es oportuno mostrarles el contexto actual de la profesión en Ciencias Económicas en Entre Ríos en lo concerniente a la ética profesional, como así también a la actuación del Tribunal de Ética.?Otra situación a analizar se relaciona con el interés por conocer el funcionamiento y\/o actividades que ha estado desarrollando el Tribunal de Ética de la Provincia.Si bien el Consejo Profesional en Ciencias Económicas de Entre Ríos (CPCEER) posee información sobre la actuación de su tribunal de ética, así como de las actuaciones y las sanciones aplicadas, no existe un registro uniforme ni conocimiento sobre estos temas a nivel provincial. Por lo tanto, este trabajo pretende servir, además de material de estudio para la cátedra, a la profesión en general, para tomar conocimiento de la evolución del tema en los últimos seis años. Con el objetivo de conocer el estado, situación y evolución del juzgamiento de los profesionales matriculados en ciencias económicas a nivel provincial en los últimos seis años (2010-2015), se elaboró y remitió al Tribunal de Ética del CPCEER, un cuestionario auto-administrado.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239552,"idioma_id":4,"titulo":"PRECARIZACIÓN LABORAL EN LAS BODEGAS DE MAIPÚ, MENDOZA: LA PERCEPCIÓN DE LOS TRABAJADORES SOBRE SUS CONDICIONES DE TRABAJO","resumen":"El artículo tiene como objetivo realizar una aproximación al análisis de las condiciones de trabajo de los operarios de bodega de Maipú, Mendoza, y observar cómo los mismos perciben esta situación. La hipótesis desarrollada plantea que los operarios divisan que sus condiciones laborales han sido degradadas en el período analizado. Se examina cómo la flexibilización y precarización laboral han aumentado en el período estudiado (1990-2014) debido a las políticas desarrolladas tanto por las empresas como por los gobiernos a través de la legislación, lo cual es percibido por los operarios como una degradación de sus condiciones de vida y de trabajo. La investigación parte de los estudios existentes sobre el tema, analizando particularmente los cambios que se produjeron en la reconversión productiva, en algunas legislaciones del trabajo entre los años 1990 y 2014 y en el convenio colectivo vitivinícola, información que se complementa con entrevistas a trabajadores del sector. Así observamos que en la etapa estudiada las condiciones de trabajo son cada vez más precarias, caracterizada por los acelerados ritmos de producción, largas jornadas de trabajo, salarios bajos, contratos cortos, polivalencia, accidentes de trabajo, y poca o nula sindicalización, entre otras características. Estas categorías son, en general, percibidas por los operarios, como perjudiciales para su desarrollo laboral y personal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239553,"idioma_id":5,"titulo":"La relación entre los niveles educativos y la precarización laboral en los\/as obreros\/as de bodegas del Gran Mendoza (2003-2014)","resumen":"El siguiente trabajo muestra los primeros resultados de una investigación mayor que aborda la relación entre el trabajo precario y los niveles educativos de los\/as trabajadores\/as de bodega de la zona del Gran Mendoza entre 2003 y 2014.     El trabajo precario se profundiza en los años 90, y con esto, los requerimientos educativos para acceder al empleo se elevan.     En las bodegas mendocinas, la precarización laboral y el trabajo informal han crecido, por lo cual encontramos trabajadores\/as de distintos niveles educativos ocupando puestos de operarios\/as. Sin embargo, sus tareas no muestran relación con sus niveles educativos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239554,"idioma_id":5,"titulo":"Fuerza pragmática y carácter institucional del lenguaje: entre la acción comunicativa y el poder simbólico","resumen":"El presente artículo toma como trasfondo las elaboraciones teóricas sobre el lenguaje realizadas por Wittgenstein y Austin y aborda en plan comparativo la manera en que las propuestas de Habermas y Bourdieu reelaboran los hallazgos teóricos de aquella perspectiva pragmática original. En particular, nos interesa analizar el modo en que el carácter institucional atribuido al lenguaje es retomado en la teoría de la acción comunicativa de Habermas y la pragmática sociológica de Bourdieu, con el propósito de mostrar y confrontar dos modos posibles, distintos e irreductibles entre sí, de apropiarse de la fuerza heurística que yace en el giro pragmático inaugurado por Wittgenstein y Austin a mediados del siglo XX.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239555,"idioma_id":5,"titulo":"Forcejeos y soplidos en la dramaturgia del materialismo derrideano","resumen":"Resumen: Este artículo ordena la lectura que a lo largo de más de treintaaños realizó Jacques Derrida de Antonin Artaud. Para ello recorre trestextos: ?La palabra soplada? de 1967, Forcener le subjectil, de 1986 y Artaudle Moma, de 1996. Cada uno de estos textos ofrece, a su vez, una lecturade Artaud que podríamos llamar materialista, entre otros motivos, porqueestá anclada temporalmente. Además, la lectura materialista le permite aDerrida impugnar las interpretaciones más usuales acerca de Artaud ?decuño idealista?, que sostienen la unidad de la locura y la obra, y la posibilidaddel encierro (Artaud, la momia de museo). Por medio de la afirmación de tres?órganos? o momentos corporales como la mano, la lengua y el ojo, Derridapone a Artaud en el tiempo y ?especialmente? lo ubica en el hoy.Palabras clave: temporalidad \/ subjectil \/ ojo","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239557,"idioma_id":5,"titulo":"El registro m&aacute;s antiguo de Chasicotatus ameghinoi Scillato-Yan&eacute;, 1977 (Xenarthra, Dasypodidae) en el Tortoniano medio de La Quebrada de Amaicha (Tucum&aacute;n, Argentina): consideraciones bioestratigr&aacute;ficas","resumen":"ABSTRACT ? THE OLDEST RECORD OF CHASICOTATUS AMEGHINOI SCILLATO-YANÉ, 1977 (XENARTHRA,DASYPODIDAE) IN THE MIDDLE TORTONIAN OF QUEBRADA DE AMAICHA (TUCUMÁN, ARGENTINA):BIOSTRATIGRAPHIC CONSIDERATIONS. The aim of this work is to present the oldest record of the genus Chasicotatus in northwest Argentina and the first record of a mammal, in fluvio-lakeside sediments of San José Formation (upper Miocene-middle Tortonian). It corresponds to a fragment of the dorsal carapace with articulated movable and fixed osteoderms, which comes from the proximity of the stream La Quenquiada, about 7 km southeast of Amaicha del Valle, Tafí del Valle department, Tucumán province, Argentina. The specimen is assigned to Chasicotatus ameghinoi by the external morphology of the movable and fixed osteoderms. The bearing levels of the San José Formation are correlated with the middle and upper levels of the Arroyo Chasicó Formation, in Buenos Aires Province, and Los Baños Member (lower member) of Chiquimil Formation in the Hualfín-Belen valley, in Catamarca Province. Paleofloristic records allow to infer a warm, seasonal climate and an environment with open forests and savannas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239559,"idioma_id":4,"titulo":"Implications of microRNA dysregulation in the development of prostate cancer","resumen":"MicroRNAs (miRNAs) are non-coding small RNAs that target mRNA to reduce protein expression. They play fundamental roles in several diseases, including prostate cancer (PCa). A single miRNA can target hundreds of mRNAs and coordinately regulate them, which implicates them in nearly every biological pathway. Hence, miRNAs modulates proliferation, cell cycle, apoptosis, adhesion, migration, invasion and metastasis, most of them constituting crucial hallmarks of cancer. Due to these properties, miRNAs emerged as promising tools for diagnostic, prognosis and management of cancer patients. Moreover, they come out as potential targets for cancer treatment and several efforts are being made to progress in the field of miRNA-based cancer therapy.In this review we will summarize the recent information about miRNAs in PCa. We will recapitulate all the miRNAs involved in the androgen pathway and the biology of PCa, focusing in PCa initiation and progression. In particular, we will describe the miRNAs associated with cell proliferation, cell cycle and apoptosis in PCa, as well as invasion, adhesion and metastatic miRNAs. We will revise the recent progress made understanding the role of circulating miRNAs34 identified in PCa that might be useful for PCa patient stratification. Another key aspect to be discussed in this review is miRNA role in PCa therapy, including miRNAs delivery.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239560,"idioma_id":4,"titulo":"Standardization of Immunobiological Assay for Determines Identity of Junin virus Vaccine, Candid# 1","resumen":"The quality control tests of the Candid#1 vaccine required forinternal release needs the use of rabbit immune serum (RIS). It is abiological reagent produced in INEVH and it must be qualified to ensureits proper use. The aim of this study was to estimate the expandeduncertainty (U) through validation studies of identity test in which thetitles of IRS are determined, and thus establish its specification foruse in control tests where the title of it is critical.Validation studies made possible calculate the U establishedby statistical analysis of the values obtained experimentally inintermediate precision, resulting=0.30. Determination of the U of themethodology established that 500 is the minimum qualification thatmust have an IRS to be used in quality control testing of the vaccineCandid# 1.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239562,"idioma_id":4,"titulo":"Essential oil chemotypes of Aloysia citrodora (Verbenaceae) in Northwestern Argentina","resumen":"Chemical biodiversity of essential oils of natural populations of Aloysia citrodora Palau (&ldquo;lemon verbena&rdquo;, &ldquo;cedr&oacute;n&rdquo;) in Northwestern Argentina was assessed by collecting in the same sites through different years. A total of 36 samples were collected in the Provinces of Salta (El Maray, La Paya, El Sunchal, El Alisal, Chorrillos), Jujuy (Chilcayo, San Roque), Catamarca (Mutquin, Colana) and Tucum&aacute;n (Amaicha del Valle) in Argentina. Essential oils were obtained by hydrodistillation (Clevenger) of naturally air-dried plant material. Yields ranged from 0.16% to 1.93% (v\/w), being the highest those of the collections of Mutquin. More than 65 compounds were identified by CG-FID-MS. Only 19 of these constituents, accounting from 77.3 to 98.9% of the total oil, present in more than 4.0% in at least one sample, were considered as variables for statistical analysis. Agglomerative Hierarchical Cluster analysis was conducted, showing at 65% of similarity, five groups. This grouping was in direct accordance to the biosynthetic pathways of main compounds (chemotypes). In the two sites of Jujuy, 21 collections evidenced four different chemotypes, named after the dominant component as follows: thujones, citronellal, carvone, and citral (neral + geranial). In the populations of Salta and Catamarca, linalool appeared as a new different chemotype. Though cedron is considered as a citral-bearing plant, curiously, in the 36 samples collected in the NW of Argentina, only two samples contained citral as main constituent. On the other hand, a dominance of citronellal and thujones compositions were found in the bulk of the samples collected, while others had very high content of linalool or carvone and its derivatives. Northwestern Argentina has repeatedly been mentioned as the center of biodiversity of this species. The new evidences found on the chemical biodiversity of essential oils of Aloysia citrodora in natural populations in this region, reinforce firmly this idea.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239563,"idioma_id":5,"titulo":"Estabilidad de la Vacuna Candid # 1 para Prevenir la Fiebre Hemorrágica Argentina","resumen":"Resumen&nbsp;&nbsp; Candid#1 es la primera vacuna a virus vivo atenuado producida y registrada en Argentina. Se produce en el INEVH desde 2003 para prevenir la fiebre hemorrágica argentina y se obtiene mediante cosecha de sobrenadantes de cultivos de células diploides infectadas con una cepa atenuada del virus Junín, formulación y posterior liofilización. Su estabilidad es crucial para asegurar su efectividad. El objetivo de este trabajo fue evaluar la estabilidad de Candid#1 exponiéndola a distintas condiciones de temperatura y tiempo. Tres lotes producidos en 2003 fueron sometidos al siguiente esquema de almacenamiento: (a) vacuna reconsti- tuida conservada entre 2 °C y 8 °C durante 8 días, (b) vacuna liofilizada conservada entre 2 °C y 8 °C durante 6 meses, y (c) vacuna liofilizada conservada entre -18 °C y -20 °C durante 10 años. La potencia fue evaluada en monocapa de células Vero bajo agar. Los resultados fueron: (a) Candid#1 reconstituida fue estable 8 días entre 2 °C y 8 °C, (b) Candid#1 liofilizada fue estable 2 meses entre 2 °C y 8 °C y (c) Candid#1 liofilizada fue estable 9 años entre -18 °C y -20 °C manteniendo todos sus atributos. Estos resultados permitieron establecer las siguientes condiciones de almacenamiento: reconstituida 12 horas entre 2 °C y 8 °C, liofilizada 30 días entre 2 °C y 8 °C y 9 años entre -18 °C y -20 °C. A la luz de estos resultados, se generaron cambios favorables en las condiciones de transporte, almacenamiento y distribución de la vacuna. Se implementó la instalación de freezers domésticos en centros estratégicamente distribuidos, permitiendo preservar stocks de vacuna y distribuir las dosis necesarias a vacunatorios.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239564,"idioma_id":4,"titulo":"A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-&beta;-lactamases","resumen":"Carbapenem-resistant Enterobacteriaceae threaten human health, since carbapenems arelast resort drugs for infections by such organisms. Metallo-&#946;-lactamases (M&#946;Ls) are the mainmechanism of resistance against carbapenems. Clinically approved inhibitors of MBLs arecurrently unavailable as design has been limited by the incomplete knowledge of theirmechanism. Here, we report a biochemical and biophysical study of carbapenem hydrolysisby the B1 enzymes NDM-1 and BcII in the bi-Zn(II) form, the mono-Zn(II) B2 Sfh-I and themono-Zn(II) B3 GOB-18. These M&#946;Ls hydrolyse carbapenems via a similar mechanism, withaccumulation of the same anionic intermediates. We characterize the Michaelis complexformed by mono-Zn(II) enzymes, and we identify all intermediate species, enabling us topropose a chemical mechanism for mono and binuclear M&#946;Ls. This common mechanismopen avenues for rationally designed inhibitors of all M&#946;Ls, notwithstanding the profounddifferences between these enzymes? active site structure, &#946;-lactam speci&#64257;city and metalcontent","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239565,"idioma_id":4,"titulo":"Ferritin Decorated PLGA\/Paclitaxel Loaded Nanoparticles Endowed with an Enhanced Toxicity Toward MCF-7 Breast Tumor Cells","resumen":"PolyLactic and Glycolic Acid nanoparticles (PLGA-NPs), coated with L-Ferritin,are exploited for the simultaneous delivery of paclitaxel and an amphiphilic Gd based MRI contrast agent into breast cancer cells (MCF7). L-Ferritin has been covalently conjugated to the external surface of PLGA-NPs exploiting NHS activated carboxylic groups. The results confirmed that nanoparticles decorated with L-Ferritin have many advantages with respect both albumin-decorated and non-decorated particles. Ferritin moieties endow PLGA-NPs with targeting capability, exploiting SCARA5 receptors overexpressed by these tumour cells, that results in an increased paclitaxel cytotoxicity. Moreover, protein coating increased nanoparticle stability thus reducing the fast and aspecific drug release before reaching the target. The theranostic potentiality of the nanoparticles has been demonstrated by evaluating the signal intensity enhancement on T1-weighted MRI images of labelled MCF7 cells. The results werecompared with that obtained with MDA cells used as negative control due to their lower SCARA5 expression.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239566,"idioma_id":4,"titulo":"Land-atmosphere interaction patterns in southeastern South America using satellite products and climate models","resumen":"In regions of strong Land-Atmosphere (L-A) interaction, soil moisture (SM) conditions can impact the atmosphere through modulating the land surface fluxes. The importance of the identification of L-A interaction regions lies in the potential improvement of the weather\/seasonal forecast and the better understanding of the physical mechanisms involved. This study aims to compare the terrestrial segment of the L-A interaction from satellite products and climate models, motivated by previous modeling studies pointing out southeastern South America (SESA) as a L-A hotspot during austral summer. In addition, the L-A interaction under dry or wet anomalous conditions over SESA is analyzed. To identify L-A hotspots the AMSRE-LPRM SM and MODIS land surface temperature products; coupled climate models and uncoupled land surface models were used. SESA highlights as a strong L-A interaction hotspot when employing different metrics, temporal scales and independent datasets, showing consistency between models and satellite estimations. Both AMSRE-LPRM bands (X and C) are consistent showing a strong L-A interaction hotspot over the Pampas ecoregion. Intensification and a larger spatial extent of the L-A interaction for dry summers was observed in both satellite products and models compared to wet summers. These results, which were derived from measured physical variables, are encouraging and promising for future studies analyzing L-A interactions.L-A interaction analysis is proposed here as a meeting point between remote sensing and climate modelling communities of Argentina, within a region with the highest agricultural and livestock production of the continent, but with an important lack of in-situ SM observations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239567,"idioma_id":4,"titulo":"Essential oil chemotypes of Aloysia citrodora (Verbenaceae) in Northwestern Argentina","resumen":"Chemical biodiversity of essential oils of natural populations of Aloysiacitrodora Palau (?lemon verbena?,?cedron?) in Northwestern Argentina was assessed by collecting in the samesites through different years. A total of 36 samples were collected in theProvinces of Salta (El Maray, La Paya, El Sunchal, El Alisal, Chorrillos),Jujuy (Chilcayo, San Roque), Catamarca (Mutquin, Colana) and Tucuman(Amaicha delValle) in Argentina.Essential oils were obtained by hydrodistillation (Clevenger) of naturallyair-dried plant material. Yields ranged from 0.16% to 1.93% (v\/w), being thehighest those of the collections of Mutquin. More than 65 compounds wereidentified by CG-FID-MS. Only 19 of these constituents, accounting from 77.3to 98.9% of the total oil, present in more than 4.0% in at least one sample,were considered as variables for statistical analysis. AgglomerativeHierarchical Cluster analysis was conducted, showing at 65% of similarity,five groups. This grouping was in direct accordance to the biosyntheticpathways of main compounds(chemotypes) In the two sites of Jujuy, 21 collections evidenced fourdifferent chemotypes, named after the dominant component as follows:thujones, citronellal, carvone, and citral (neral þ geranial). In thepopulations of Salta and Catamarca, linalool appeared as a new differentchemotype.Though cedron is considered as a citral-bearing plant, curiously, in the 36samples collected in the NW of Argentina, only two samples contained citralas main constituent. On the other hand, a dominance of citronellal andthujones compositions were found in the bulk of the samples collected, whileothers had very high content of linalool or carvone and its derivatives.Northwestern Argentina has repeatedly been mentioned as the center ofbiodiversity of this species.The new evidences found on the chemical biodiversity of essential oils ofAloysia citrodora in natural populations in this region, reinforce firmlythis idea.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239575,"idioma_id":5,"titulo":"'Antín \/ Cortázar: cruces y destiempos entre la escritura y el cine'","resumen":"Este artículo estudia la relación de colaboración mutua que mantuvieron el cineasta Manuel Antín y el narrador Julio Cortázar entre 1963 y 1965. Durante ese lapso, ambos trabajaron en la escritura de los guiones de los filmes ´Circe´ e ´Intimidad de los parques´. El vínculo que los dos construyeron en sus encuentros personales y a través de cartas da cuenta de un modo de labor inédito en el cine argentino alrededor de la escritura cinematográfica. Asimismo, el lazo entre estas dos figuras muestra un cambio estructural de la relación del cine y de la literatura en el campo cultural. En este sentido, durante los años 1960 uno y otro espacio trazan lazos sinérgicos que potencian su dimensión sociocultural. Indización: Latindex Catálogo, Latindex Directorio, Dialnet, SciELO, EBSCO.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239580,"idioma_id":4,"titulo":"Mind the gap! Integrating taxonomic approaches to assess ant diversity at the southern extreme of the Atlantic Forest","resumen":"Understanding patterns of species diversity relies on accurate taxonomy which can only be achieved by long-term natural history research and the use of complementary information to establish species boundaries among cryptic taxa. We used DNA barcoding to characterize the ant diversity of Iguazú National Park (INP), a protected area of the Upper Paraná Atlantic Forest ecoregion, located at the southernmost extent of this forest. We assessed ant diversity using both cytochrome c oxidase subunit 1 (COI) sequences and traditional morphological approaches, and compared the results of these two methods. We successfully obtained COI sequences for 312 specimens belonging to 124 species, providing a DNA barcode reference library for nearly 50% of the currently known ant fauna of INP. Our results support a clear barcode gap for all but two species, with a mean intraspecific divergence of 0.72%, and an average congeneric distance of 17.25%. Congruently, the library assembled here was useful for the discrimination of the ants of INP and allowed us to link unidentified males and queens to their worker castes. To detect overlooked diversity, we classified the DNA barcodes into Molecular Operational Taxonomic Units (MOTUs) using three different clustering algorithms, and compared their number and composition to that of reference species identified based on morphology. The MOTU count was always higher than that of reference species regardless of the method, suggesting that the diversity of ants at INP could be between 6% and 10% higher than currently recognized. Lastly, our survey contributed with 78 new barcode clusters to the global DNA barcode reference library, and added 36 new records of ant species for the INP, being 23 of them new citations for Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239581,"idioma_id":5,"titulo":"METODOLOGIA PARA EVALUAR EL RENDIMIENTO ACADÉMICO DE UNA CÁTEDRA","resumen":"El presente estudio, tiene por objetivo: ?Proponer una metodología de evaluación del Rendimiento Académico de una Cátedra a fin de tener un diagnóstico de la misma?.El Rendimiento Académico de una cátedra es el indicador que está constituido por tres  dimensiones: rendimiento, eficiencia y desgranamiento. Las cuales tienen las siguientes características: a)Dimensión Rendimiento, donde consideramos las notas obtenidas en los exámenes; b) Dimensión Eficiencia, donde contemplamos la forma en que los estudiantes aprueban la materia, c) Dimensión temporal, donde analizamos la continuidad o discontinuidad de los estudiantes en el ritmo temporal relativo al año académico.  Realizamos el diagnóstico de la cátedra de Matemática II, de la Facultad de Bioquímica, Química y Farmacia de la UNT.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239582,"idioma_id":5,"titulo":"Participación y Promoción de salud: procesos de construcción social a escala local","resumen":"Si bien la vida de la comunidad se desarrolla en un entramado de factores y acciones que desde la salud integral son dimensiones y determinantes, en Nueva Francia emerge como problema la visión polarizada de las prácticas que instrumenta la posta sanitaria y la comunidad. El proyecto de investigación Participación y Promoción de Salud: Procesos de Construcción Social a Escala Local plantea como objetivo general conocer la configuración de los procesos participativos y su vinculación con la promoción de la salud individual y comunitaria. Es un estudio exploratorio-descriptivo con metodología IAP. Trabaja con dos universos, uno constituido por 364 hogares y otro por el personal de la Posta Sanitaria (10 integrantes). Conforman las muestras 91 hogares y 5 miembros del equipo de salud siendo las unidades de análisis un representante por hogar mayor de edad residente permanente en la localidad y un representante por tipo de servicio que presta y permanencia en el centro de salud. Los datos se recogen a través de entrevistas semiestructuradas y en profundidad y grupos focales. Los resultados parciales dan cuenta del proceso y permiten avanzar con propuestas de acción participativa en la línea que proclaman los organismos mundiales de promoción de la salud.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239583,"idioma_id":5,"titulo":"Participación y Promoción de salud: procesos de construcción social a escala loca","resumen":"Si bien la vida de la comunidad se desarrolla en un entramado de factores y acciones que desde la salud integral son dimensiones y determinantes, en Nueva Francia emerge como problema la visión polarizada de las prácticas que instrumenta la posta sanitaria y la comunidad. El proyecto de investigación Participación y Promoción de Salud: Procesos de Construcción Social a Escala Local plantea como objetivo general conocer la configuración de los procesos participativos y su vinculación con la promoción de la salud individual y comunitaria. Es un estudio exploratorio-descriptivo con metodología IAP. Trabaja con dos universos, uno constituido por 364 hogares y otro por el personal de la Posta Sanitaria (10 integrantes). Conforman las muestras 91 hogares y 5 miembros del equipo de salud siendo las unidades de análisis un representante por hogar mayor de edad residente permanente en la localidad y un representante por tipo de servicio que presta y permanencia en el centro de salud. Los datos se recogen a través de entrevistas semiestructuradas y en profundidad y grupos focales. Los resultados parciales dan cuenta del proceso y permiten avanzar con propuestas de acción participativa en la línea que proclaman los organismos mundiales de promoción de la salud.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239588,"idioma_id":5,"titulo":"De políticas globales e itinerarios de atención: un estudio etnográfico de las estrategias de prevención de la transmisión perinatal del VIH en un hospital público del Gran Buenos Aires.","resumen":"Este artículo analiza las estrategias de prevención de la transmisión madre-hijo del VIH a partir de un estudio etnográfico del proceso de atención a mujeres con VIH en un hospital público del Gran de Buenos Aires. A partir del análisis de los dispositivos de atención y los itinerarios terapéuticos la perspectiva etnográfica posibilitó captar un proceso simultáneo de visibilización e invisibilización de las mujeres con VIH y sus embarazos, en el marco de la atención hospitalaria. Por un lado, estas mujeres son objetos de intervención en tanto sujetos de experimentación y fuente de datos estadísticos y evidencia para estudios científicos globales. Por el otro, sus necesidades y demandas son invisibles frente a otros problemas de salud y otras prioridades del sistema de atención.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239589,"idioma_id":5,"titulo":"Espacio, tiempo y poder en la atención hospitalaria de la salud y la enfermedad. Aportes de una etnografía de un centro obstétrico.","resumen":"Este artículo presenta resultados de una etnografía de un centro obstétrico deun hospital del Gran Buenos Aires a partir del análisis de la dimensión espacio-temporal de la atención hospitalaria. El trabajo de campo, llevado a cabo entre 2007 y 2011, incluyó la observación en la unidad de obstetricia (salas de espera, consultorios externos, sala de ecografías, sala de internación, centro obstétrico dónde se atienden los partos y emergencias, entre otros) y en otros espacios como los servicios de turnos y de estadísticas, las oficinas del servicio social, el hall central, la farmacia, los pasillos de espera, etc. Además, se realizaron entrevistas a jefes de servicio, médicos\/as obstetras, enfermeros\/as, trabajadoras sociales, personal del laboratorio y del servicio de estadísticas y turnos, voluntarios\/as y pacientes. Así, se analizan las rutinas médico-burocráticas de la admisión y la internación de mujeres en el centro obstétrico; las disputas, transacciones y negociaciones entre profesionales, pacientes y familiares; la delimitación de espacios y las secuencias y jerarquías temporales en el pasaje del ?afuera? hacia el ?adentro? del hospital.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239590,"idioma_id":4,"titulo":"An Inverse Problem for the Caputo Fractional Derivative by Means of the Wavelet Transform","resumen":"In this article, we build an approximate solution to an Inverse Problem that consist in finding a function whose Caputo Fractional Derivative is given. We decompose and project the data in appropriate wavelet subspaces and, by a Galerkin scheme, we calculate the coefficients of the unknown function in the chosen wavelet basis. Based on properties of the operator and of the basis, the scheme is efficient and the errors introduced by the approximation can be handled and controlled. We illustrate the results with an example.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239593,"idioma_id":4,"titulo":"Changes of Benthic Macrofaunal Composition on a Tidal Flat of Rio Gallegos Estuary, Argentina","resumen":"This work analyzed the variation in composition and abundance of benthicassemblages in an intertidal environment of the Río Gallegos estuary, Argentina(51°35´ S - 69° 01´ W). The macrofauna was sampled in a tidal flat adjacent to the cityin late summer of 2006 and 2013 (March). In total 27 macrofauna taxa were identified;the most abundant species were Darina solenoides (44%) in 2006 and Fabricinuda sp.(89%) in 2013. Biogenic structures composed of aggregates of polychaete(Fabricinuda sp.) tubes and sediment were observed for the first time in December2006; they are spherical or of irregular shape, 1 to 3 m2 in area, and up to 50 cm inheight. In 2013 benthic composition was compared between biogenic aggregates('patch') and the area outside them ('non-patch'). Species richness and totalabundance of individuals were higher in the patch. The associated benthos wasdifferent; Fabricinuda sp. was dominant in the patch (107780.7 indiv.m-2, SD=44772.6)and Kinbergonuphis dorsalis (2139 indiv.m-2, SD=840) and Notocirrus lorum (1830indiv.m-2, SD=516.4) in the non-patch. In 2013, four taxa that were not found in 2006were recorded only in the patch samples, two bivalves (Sphenia hatcheri and Malletiacumingii) and two polychaetes (Fabricinuda sp. and Ophioglycera eximia). Polychaeteaggregations have produced changes in number and abundance of benthic species atthe lowest level of the tidal flat.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239594,"idioma_id":5,"titulo":"La Nueva Derivada de Caputo: Cálculo Aproximado de Primitivas Utilizando una Familia de Wavelets de Banda Limitada","resumen":"La nueva derivada de Caputo est\\'a definida mediante un operador integral con n\\'ucleo regular,  (\\cite{caputo}). En este trabajo, continuaci\\'on de  (\\cite{tropa1}),  resolvemos aproximadamente la ecuaci\\'on $D^{\\alpha}_{*} f=g, \\;\\; 0<\\alpha<1, $ donde $D^{\\alpha}_{*} f$ es la nueva derivada de Caputo de orden $\\alpha$  de $f$ y $g$ es el dato. Para calcular aproximadamente una primitiva $f$ elegimos una familia de wavelets de banda limitada de  propiedades especiales asociadas a un an\\'alisis de multirresoluci\\'on. Descomponemos y proyectamos el dato y mediante un esquema tipo Galerkin calculamos los coeficientes de la inc\\'ognita en dicha base.El esquema de aproximaci\\'on resulta simple y eficiente gracias a la regularidad del operador y a las propiedades de la familia de wavelets elegida.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239595,"idioma_id":4,"titulo":"Reactive oxygen species generated in chloroplasts contribute to tobacco leaf infection by the necrotrophic fungus Botrytis cinerea","resumen":"Reactive oxygen species (ROS) play fundamental roles in plant responses to pathogen infection, including modulation of cell death processes and defense-related gene expression. Cell death triggered as part of the hypersensitive response enhances resistance to biotrophic pathogens, but favors virulence of necrotrophs. Even though the involvement of ROS in the orchestration of defense responses is well established, the relative contribution of specific subcellular ROS sources to plant resistance against microorganisms with different pathogenesis strategies is not completely known. The aim of this work was to investigate the role of chloroplastic ROS in plant defense against a typical necrotrophic fungus, Botrytis cinerea. For this purpose, we used transgenic tobacco lines expressing a plastid-targeted cyanobacterial flavodoxin (pfld lines), which accumulate lower chloroplastic ROS in response to different stresses. Tissue damage and fungal growth were significantly reduced in infected leaves of pfld plants, as compared to infected wild-type (WT) counterparts. ROS build-up triggered by Botrytis infection and associated to chloroplasts was significantly decreased (70-80%) in pfld leaves relative to the wild type. Phytoalexin accumulation and expression of pathogenesis-related genes were induced to a lower degree in pfld plants than in WT siblings. The impact of fungal infection on photosynthetic activity was also lower in pfld leaves. The results indicate that chloroplast-generated ROS play a major role in lesion development during Botrytis infection. This work demonstrates that the modulation of chloroplastic ROS levels by expression of a heterologous antioxidant protein can provide a significant degree of protection against a canonical necrotrophic fungus.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239597,"idioma_id":5,"titulo":"DE VENADOS, ARMADILLOS Y COIPOS: LOS MAMÍFEROS AUTÓCTONOS FRENTE A LOS CAMBIOS EN EL USO DEL SUELO, LOS MANEJOS AGROPECUARIOS Y LA PRESENCIA DE NUEVOS ELEMENTOS EN EL PAISAJE RURAL","resumen":"La actividad agropecuaria ha sido, y continúa siendo, una gigantesca fuerza transformadora denuestro planeta. Los agroecosistemas de las pampas, en Argentina, no han sido la excepción a estas transformaciones:a la expansión agrícola y la masiva adopción del sistema de siembra directa, se le ha sumado elreordenamiento territorial y la intensificación de la ganadería. A su vez, obras de infraestructura (caminos, canalizaciones,terraplenes) impusieron nuevas configuraciones al paisaje rural ¿Cómo ha respondido la mastofaunaa estos cambios? En este trabajo sintetizamos los resultados registrados, entre los cuales podemos señalar: 1) unmarcado uso diferencial de lotes por parte de las especies de armadillos más comunes, con mayor actividad depeludos (Chaetophractus villosus) en rastrojos agrícolas y de mulitas (Dasypus hybridus) en campos ganaderos,2) que la coexistencia entre venados de las pampas (Ozotoceros bezoarticus) y ganado vacuno solo es posiblebajo sistemas de pastoreo que ofrezcan períodos de descanso a los potreros o bajo esquemas de baja cargaganadera, y 3) que los coipos (Myocastor coypus) utilizan diferencialmente los canales artificiales en períodosmás secos. Se discuten las oportunidades y desafíos que estas respuestas tienen para la conservación de especiesamenazadas o el manejo de especies potencialmente conflictivas, y se señalan algunas necesidades futuras deinvestigación en función de los cambios que continúan operando sobre estos sistemas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239598,"idioma_id":4,"titulo":"Spatial segregation among pampas deer and exotic ungulates: a comparative analysis at site and landscape scales","resumen":"The pampas deer (Ozotoceros bezoarticus) is native to South America and is endangered in Argentina. In BuenosAires province, Argentina, the last population of pampas deer is harbored in the Bahía Samborombón WildlifeRefuge (BSWR), which includes protected areas and numerous cattle ranches. This population has been decliningand changing progressively in its distribution since 1985, and negative interactions between pampas deer andintroduced ungulates (livestock and feral pigs) have been proposed among the main causes of its decline. Weexamined the abundance, distribution, and interactions among pampas deer, cattle, and feral pigs at site andlandscape scales in the BSWR. At the site scale, coexistence between pampas deer and cattle at the same paddockwas only possible at moderate stocking rates (0.2?0.4 AU\/ha), and no deer were recorded at paddocks whenstocking rates were above 0.6 AU\/ha. Pampas deer and feral pigs co-occurred more frequently, but deer switchedtheir behavior and increased levels of surveillance in response to proximity of feral pigs. At the landscape scale, aclear spatial segregation and differential distribution was detected among pampas deer, cattle, and feral pigs alongthe BSWR. Our results suggest that the current distribution of pampas deer at the study area is a consequence ofavoiding contact with both livestock and feral pigs at the site scale. Thus, negative interactions recorded betweenpampas deer and introduced ungulates at the site scale were expressed at the landscape scale. Both in situ and exsitu conservation efforts are urgently needed to conserve pampas deer.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239599,"idioma_id":4,"titulo":"Multivariate Characterization of Biological Efficiency in Dairy Cows in Grazing Systems","resumen":"Retrospective data was used corresponding to the lactation of 216 first and multi-pregnancy cows,American-Canadian Holstein with registers of their whole productive life, from their entrance to the system till their sale or death, registers were gathered from1992-2012 in the Argentinian Holstein farm located in Casilda, province of Santa ?Argentina. During the mentioned time, all the cows were managed in the same dairy premises. The animals were divided into two categories: pure cows (VP,n=88) and cows with breeding registers (VRC,n =128). The variables under use were: age at first calving, in days (EPP), first calving ? conception interval in days (IPP), milk production adapted to 305 lactation days, in litres (PL), the amount of butyric fat produced, in kilograms (GB), the number of calvings registered throughout its reproductive life (NP), milk index in litres (IL) and the fat index in kilograms (IG). There were statistically significant differences as regards the productive characteristics PL and GB. N average, throughout the cycle under study, the VP produced 591 litres of milk and 161 kg of fat more. There were no significant differences when considering the age of first calving or the calving ? conception interval. VP cows registered higher IL and IG than VRC cows, with significant differences whichfavoured the former, in both cases. The four components generated by the multivariate analysis explained important portions of the total variance which lead to consider all of them when interpreting the joint relations between productive performance indicators and reproductive achievement. It is concluded that even though the biotypes under study behave differently, both coincide at the point of stating that those cows which belong to quadrant IV were those which presented the best adaptation to the environment, being the ones who live longer and with an intermediate reproductive efficiency, regardless their biotype","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239602,"idioma_id":5,"titulo":"Los alimentos irradiados y la carrera por la conservación","resumen":"Ya sea por carencias cuanti\/cualitativas, falta deinocuidad o pérdidas\/ desperdicios la necesidad de producir, proteger yconservar los alimentos y sus características estructurales, organolépticas ynutritivas constituyen una estrategia clave para mejorara la seguridadalimentaria y nutricional de la población mundial.Dentro de los diferentes métodos físicos deconservación de alimentos, como la pasteurización o la refrigeración, sedestaca la irradiación como uno de los métodos con más potencial y capacidad dedesarrollo para diferentes aplicaciones en los alimentos y sus ingredientes.Esta tecnología se basa en la exposición del producto a la acción deradiaciones ionizantes, durante un lapso de tiempo proporcional a la cantidadde energía que se pretende absorba el alimento con el propósito de lograr elcontrol de microorganismos alterantes y patógenos, la inhibición de labrotación, la desinfestación y el retraso de la maduración.La irradiación de los alimentos es una alternativaválida a la hora de pensar en diferentes formas de conservar los alimentos,dado que presenta ventajas con respecto a las tecnologías tradicionales. Entreellas se destaca su condición de proceso 'frío', lo que da lugar altratamiento de productos frescos en los que no es posible aplicar los métodostérmicos convencionales. Esto la convierte, además, en una interesante opciónpara alimentos con componentes termosensibles.La irradiación de alimentos proporciona un medioeficaz para controlar los agentes biológicos contaminantes sin introducirsustancias extrañas ni someterlos a la acción del calor, manteniendo intacta sucalidad y prolongando su vida útil. Permite combatir insectos y parásitos a lavez que reducir y\/o evitar el uso de sustancias químicas con potencialtoxicidad para el operador, el consumidor y el ambiente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239604,"idioma_id":5,"titulo":"La Ley de Lemas: el caso santafecino en clave historiográfica","resumen":"El presente artículo pretende indagar, desde una perspectiva historiográfica renovada, un caso excepcional de una temática ampliamente abordada por la literatura politológica. La Ley de Lemas ha sido la reforma política de mayor extensión desde el retorno democrático, en función de lo cual ha atraído la atención de los estudiosos.El enfoque adoptado permite echar luz sobre una serie de características específicas del caso santafecino, las cuales lo distancian de los modelos explicativos elaborados a partir de las premisas del rational choice. En miras de ese objetivo, se recrea todo el recorrido institucional de la ley a partir del análisis de los debates ocurridos en el Congreso.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239605,"idioma_id":4,"titulo":"Effect of hyperthyroidism on circulating prolactin and hypothalamic expression of tyrosine hydroxylase, prolactin signaling cascade members and estrogen and progesterone receptors during late pregnancy and lactation in the rat","resumen":"&amp;amp;amp;amp;amp;lt;!-- \/* Font Definitions *\/@font-face{font-family:Arial;panose-1:2 11 6 4 2 2 2 2 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:3 0 0 0 1 0;}@font-face{font-family:Cambria;panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:3 0 0 0 1 0;} \/* Style Definitions *\/p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-parent:'';margin:0cm;margin-bottom:.0001pt;mso-pagination:widow-orphan;font-size:12.0pt;font-family:'Times New Roman';mso-ascii-font-family:Cambria;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:Cambria;mso-fareast-theme-font:minor-latin;mso-hansi-font-family:Cambria;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:'Times New Roman';mso-bidi-theme-font:minor-bidi;mso-fareast-language:EN-US;}@page Section1{size:595.0pt 842.0pt;margin:70.85pt 3.0cm 70.85pt 3.0cm;mso-header-margin:35.4pt;mso-footer-margin:35.4pt;mso-paper-source:0;}div.Section1{page:Section1;}--&amp;amp;amp;amp;amp;gt;Hyperthyroidism (HyperT) compromises pregnancy andlactation, hindering suckling-induced PRL release. We studied the effect ofHyperT on hypothalamic mRNA (RT-qPCR) and protein (Western blot) expression oftyrosine hydroxylase (TH), PRL receptor (PRLR) and signaling pathway members,estrogen (ERa) and progesterone (PR) receptors on late pregnancy (days G19, 20and 21) and early lactation (L2) in rats. HyperT advanced pre-partum PRLrelease, reduced circulating PRL on L2 and increased TH mRNA (G21 and L2),p-TH, PRLR mRNA, STAT5 protein (G19 and L2), PRLR protein (G21) and CIS protein(G19). PRs mRNAs and protein decreased on G19 but afterwards PRA mRNA (G20),PRB mRNA (G21) and PRA mRNA and protein (L2) increased. ERa protein increasedon G19 and decreased on G20. Thus, the altered hypothalamic PRLR, STAT5, PR andERa expression in hyperthyroid rats may induce elevated TH expression andactivation, that consequently, elevate dopaminergic tone during lactation,blunting suckling-induced PRL release and litter growth.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239610,"idioma_id":5,"titulo":"Estudio de transformaciones de fase por microscopía fototérmica","resumen":"Se presenta el desarrollo de un novedoso sistema que permite el mapeo con alta resolución espacial de la difusividad térmica en función de la temperatura hasta 1800K. El sistema se basa en una técnica fototérmi-ca recientemente desarrollada por el grupo, consistente en la medición con un láser de prueba de la curvatu-ra inducida por el calentamiento con un láser modulado. La utilización de tecnología de fibras ópticas pro-vee una alta robustez al equipo. Un horno para microscopio permite realizar rampas a velocidad controlada para el estudio de transiciones de fase y la medición de la difusividad térmica en función de la temperatura. Se pueden establecer mesetas para hacer barridos espaciales con resolución microscópica para el estudio de la evolución de las fases o hacer tratamientos térmicos in situ para estudiar luego la distribución espacial de las fases presentes. Estas capacidades se muestran a partir de la determinación de la energía de activación de la transformación de fase amorfo-cristal de una aleación de Fe-B-Si.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239611,"idioma_id":4,"titulo":"A Taphonomic Approach to marine Abrasion on Human Bones","resumen":"Coastal areas are often scenes of various phenomena linked to forensic cases, such ashomicides, suicides, naval accidents linked to clandestine migration, or simply coastalsites with human remains that are affected by aquatic phenomena. It is in this contextwhere the Taphonomy can contribute to responding to many problems within theforensic field. Our goal is to determine the morphology, density and orientation of thechanges caused by the action of marine sediments on the surface of a human femur.The use of binocular loupe, have enabled a more detailed analysis of abrasion. It hasbeen determined that abrasion traces are distributed across all surface of the boneand presented an anisotropic spatial orientation, i.e. present a non-random pattern.The results have been used to corroborate on a human bone subjected to naturalphenomena, the observations carried out in the experimental field by others authors","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239612,"idioma_id":5,"titulo":"Múltiples índices espectrales para predecir la variabilidad de atributos estructurales y funcionales en zonas áridas.","resumen":"En la región patagónica Argentina, las principales fuerzas directrices de la degradación son las actividades extractivas (petrolera y minera) y la ganadería ovina extensiva. Evaluar los atributos estructurales y funcionales de las unidades de paisaje es un paso necesario, hacia el monitoreo de los sistemas para detectar patrones asociados a la desertificación o la restauración pasiva. Uno de los principales problemas a sortear en estos ambientes es la gran extensión territorial, en ese sentido los índices espectrales provenientes de sensores remotos puedenconstituyen una herramienta útil para evaluar grandes áreas de manera exitosa. El objetivo de este trabajo fue analizar la capacidad demúltiplesíndices espectrales del satélite SPOT 5 para monitorear atributos estructurales  (cobertura vegetal de especies perennes) y funcionales  (productividad forrajera) en unidades de paisaje de Patagonia Ccentral (Argentina). Se evaluó la relación de siete índices espectrales obtenidos del satélite SPOT5, sensor HRG1 en 44 sitios ubicados en tres unidades de paisaje denominadas cañadones costeros, pampas y valles occidentales ubicados en la Patagonia Ccentral (Argentina). El DVI (DifferenceVegetationIndex) y elSAVI (SoilAdjustedVegetationIndex) fueron los mejores predictores de la cobertura vegetal de especies perennes a nivel de paisaje. El NDVI (NormalizedDifferenceVegetativeIndex) tuvo buena actuación en los cañadones costeros y el DVI en los valles occidentales. El DVI explicó el 14% de la variación de la productividad forrajeraen los valles occidentales, estimada a partir del valor pastoral del ecosistema. Los resultados de este trabajo muestran que los índices espectrales provenientes del satélite SPOT 5, principalmente el DVI,SAVI y el NDVI, son herramientas apropiadas para monitorear la estructura y función de la vegetación a nivel de las unidades de paisaje de Patagonia Central.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239614,"idioma_id":5,"titulo":"Complejo respiratorio bovino: evidencia de circulación  viral múltiple en un establecimiento de cría","resumen":"El complejo respiratorio bovino (CRB) es una de las principales causas de pérdidas productivas en rodeos de cría, tambo y engorde a corral. Los agentes infecciosos involucrados incluyen virus, bacterias y micoplasmas. Dentro de los agentes virales se encuentran el virus respiratorio sincicial bovino (bRSV), el virus parainfluenza 3 bovino (BPIV3), el herpesvirus bovino tipo 1 (BoHV1) y el virus de la diarrea viral bovina (BVDV). El objetivo de este trabajo fue evaluar la circulación de los virus asociados al CRB en un rodeo de cría, durante el período posdestete, mediante un estudio serológico longitudinal. En forma complementaria, se describieron y compararon los hallazgos clínicos y hematológicos. Se seleccionaron 32 animales de 5 a 7 meses de edad, sin vacunación previa, y se evaluó diariamente la presencia de signos clínicos compatibles con CRB. Se extrajeron muestras de sangre los días 0 (destete), +14 y +25 (momento en que culminó el ensayo). No se detectaron animales con manifestación clínica de CRB y los parámetros hematológicos se encontraron dentro del rango de referencia. Al inicio de la experiencia, ningún animal presentaba anticuerpos (Ac) específicos para bRSV, mientras que para el resto de los agentes virales, el porcentaje de animales seropositivos fue variable: 53% (BVDV1a), 31% (BPIV3), 25% (BVDV2) y 13% (BoHV1). Al día +25 los porcentajes de seropositivos fueron los siguientes: 47% (BVDV1a), 50% (BPIV3), 19% (BVDV2), 25% (BoHV1) y 81% (bSRV). Los porcentajes de seroconversión para bRSV, BPIV3, BVDV1a y BoHV1 fueron 34%, 25%, 16% y 13%, respectivamente. Además, el 66% de los animales seroconvirtió a uno o más virus. Para BVDV2 y BVDV1b no se observó seroconversión. Estos resultados evidencian la circulación, e incluso en algunos casos la coinfección de los agentes virales involucrados en el CRB en el período posdestete. Resulta importante la realización de estudios virológicos complementarios que permitan identificar y caracterizar las cepas circulantes en esta etapa productiva, principalmente en relación con bSRV y PIV3, virus de los que se posee escasa información en nuestro medio.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239617,"idioma_id":4,"titulo":"Assessment of Cu-Zn EDTA Parenteral Toxicity in Calves","resumen":"Copper (Cu) parenteral administration is used in a beef cow-calf operations to prevent or correct Cu deficiency in bovines. At present, Zinc (Zn) salts have been incorporated to complement Cu antioxidant effect. A risk of hepatotoxicity generated by overdose is a negative consequence of injectable Cu application. Cu-Zn EDTA appears as an alternative; however, data about its toxicity is unknown. The aim of this study was to assess toxicity risk of different doses of Cu-Zn EDTA in calves. Thirty two Aberdeen Angus calves of 162 (±20) kg BW were assigned to 4 groups (n = 8), homogeneous in weight, sex, and age. Cu-Zn EDTA was administrated in doses of 0.3 mg\/kg BW (group 1X); 0.6 mg\/kg BW (group 2X); 0.9 mg\/kg BW (group 3X) and sterile saline solution (control group-with no treatment). Clinical and blood parameters in animals were monitored during 28 days. In groups? control, 1X and 2X there were no alterations in the assessed parameters. In group 3X, one of the animals showed depression, permanent decubitus, and muscular twitching; that animal had to be killed in extremis for humanitarian reasons. Necropsy and Cu tissue concentration findings confirmed intoxication in the clinically affected animal. The rest of the animals in group 3X showed only a temporary increase in liver enzymes. The results indicate that a dose of 0.9 mg\/kg BW of Cu as Cu-Zn EDTA is potentially hepatotoxic, this dose is similar to other soluble salts of parenteral administration.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239620,"idioma_id":5,"titulo":"Artes en cruce como práctica significante en la obra de Emilio García Wehbi","resumen":"X","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239621,"idioma_id":4,"titulo":"ATGC transcriptomics: a web-based application to integrate, explore and analyze de novo transcriptomic data","resumen":"In the last years, applications based on massively parallelized RNA sequencing (RNA-seq) have become valuable approaches for studying non-model species, e.g., without a fully sequenced genome. RNA-seq is a useful tool for detecting novel transcripts and genetic variations and for evaluating differential gene expression by digital measurements. The large and complex datasets resulting from functional genomic experiments represent a challenge in data processing, management, and analysis. This problem is especially significant for small research groups working with non-model species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239627,"idioma_id":4,"titulo":"Exchange interaction between S = 1\/2 centers bridged by multiple noncovalent interactions: Contribution of the individual chemical pathways to the magnetic coupling","resumen":"We report EPR and magnetic measurements of diaqua-(pyridine-2,6-dicarboxylato)Copper(II) together with computational calculations. This compound consists of an extended lattice of magnetically equivalent copper(II) ions in which the copper centers are linked by hydrophobic interactions such as &#960;?&#960;, &#960;?metal, and Y?X?&#960;, and hydrogen bonds involving different topologies, viz., [sbnd]Cu[sbnd]Oeq?Oeq[sbnd]Cu[sbnd], [sbnd]Cu[sbnd]Oeq?Oap[sbnd]Cu[sbnd], and [sbnd]Cu[sbnd]Oeq?O[dbnd]C[sbnd]Oeq[sbnd]Cu[sbnd]. The powder EPR spectrum shows nearly axial symmetry with non-resolved hyperfine structure with the copper nucleus, suggesting the presence of intercenter isotropic exchange interactions. Single crystal EPR experiments show a single lorentzian resonance line for all the magnetic field orientations investigated, typical of an extended exchange coupled system. Susceptibility measurements showed weakly antiferromagnetically coupled Cu(II) ions (J = &#8722;0.79 (4) cm&#8722;1). Using Anderson´s exchange narrowing model for the collapse of the hyperfine structure, EPR yielded |J| = 0.6 (1) cm&#8722;1. The distinct contributions of the different chemical pathways to the experimentally determined J-value are analyzed through first principle computational calculations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239628,"idioma_id":4,"titulo":"2016 International meeting of the Global Virus Network","resumen":"The Global Virus Network (GVN) was established in 2011 in order to strengthen research and responses to current viral causes of human disease and to prepare against new viral pandemic threats. There are now 38 GVN Centers of Excellence and 6 Affiliate laboratories in 24 countries. GVN scientists meet annually to learn about each other´s current research, address collaborative priorities and plan future programs. The 2016 meeting was held from October 23e25 in Hokkaido, Japan, in partnership with the Japanese Society for Virology, the National Institute of Infectious Diseases of Japan and the Research Center for Zoonosis Control of Hokkaido University. This report highlights the accomplishments of GVN researchers in many priority areas of medical virology, including the current Zika epidemic, infections by human papillomavirus, influenza, Ebola, Lassa, dengue, HIV, hepatitis C, and chikungunya viruses, and the development of improved diagnostics and new vaccines.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239629,"idioma_id":5,"titulo":"RUPTURA DE LA DORMICIÓN Y EXIGENCIAS DE LUZ PARA LA GERMINACIÓN DE SEMILLAS DE Juglans nigra","resumen":"Se evaluaron métodos para superar la dormición y determinar las necesidades de luz en la germinación de Juglans nigra. Para superar la latencia y dureza del endocarpio se realizó Estratificación en caliente (T1),  Inmersión en ácido giberélico (T2) y Estratificación en frío-húmedo (T3). Para la necesidad de luz se evaluó alternancia de oscuridad\/luz y oscuridad permanente. Se analizó el Porcentaje Germinación (% de G), Índice Velocidad de Germinación (IVG), Tiempo Medio Germinación Máxima (TMG), % Plántulas Normales, % Semillas sin germinar, Peso Seco Medio de plántulas (PSM) y el Índice de Germinación Relativo a la luz (GRL). En T1 no hubo germinación y en T2 irrelevante. T3 produjo diferencias altamente significativas en todas las variables analizadas, siendo el período de 4 meses de estratificación el mejor para romper la dormición. Al no ser la luz un factor determinante en la germinación, esta especie se clasificaría como fotoblástica neutra.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239630,"idioma_id":4,"titulo":"Functional interaction between co-expressed MAGE-A proteins","resumen":"MAGE-A (Melanoma Antigen Genes-A) are tumor-associated proteins with expression in a broad spectrum of human tumors and normal germ cells. MAGE-A gene expression and function are being increasingly investigated to better understand the mechanisms by which MAGE proteins collaborate in tumorigenesis and whether their detection could be useful for disease prognosis purposes. Alterations in epigenetic mechanisms involved in MAGE gene silencing cause their frequent co-expression in tumor cells. Here, we have analyzed the effect of MAGE-A gene co-expression and our results suggest that MageA6 can potentiate the androgen receptor (AR) co-activation function of MageA11. Database search confirmed that MageA11 and MageA6 are co-expressed in human prostate cancer samples. We demonstrate that MageA6 and MageA11 form a protein complex resulting in the stabilization of MageA11 and consequently the enhancement of AR activity. The mechanism involves association of the Mage A6-MHD domain to MageA11, prevention of MageA11 ubiquitinylation on lysines 240 and 245 and decreased proteasome-dependent degradation. We experimentally demonstrate here for the first time that two MAGE-A proteins can act together in a non-redundant way to potentiate a specific oncogenic function. Overall, our results highlight the complexity of the MAGE gene networking in regulating cancer cell behavior.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239631,"idioma_id":4,"titulo":"A domain independent readability metric for web service descriptions","resumen":"Web Services are influencing most IT-based industries as the basic building block of business infrastructures. A Web Service has an interface described in a machine-processable format (specifically WSDL). Service providers expose their services by publishing the corresponding WSDL documents. Service consumers can learn about service capability and how to interact with the services. Service descriptions (WSDL documents) should be ideally understood easily by service stakeholders so that the process of consuming services is simplified. In this work we present a practical metric to quantify readability in WSDL documents ? attending to their semantics by using WordNet as the underlying concept hierarchy. In addition, we propose a set of best practices to be used during the development of WSDL documents to improve their readability. To validate our proposals, we performed both qualitative and quantitative experiments. A controlled survey with a group of (human) service consumers showed that software engineers required less time and effort to analyze WSDL documents with higher readability values. Other experiment compares readability values of a dataset of real-life WSDL documents from the industry before and after modifying them to adhere to the readability best practices proposed in this paper. We detected a significant readability improvement for WSDL documents written according to the best practices. In another experiment, we applied existing readability metrics for natural language texts detecting their unsuitability to the Web Service context. Lastly, we analyzed the readability best practices identifying their useful applicability to the industry.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239633,"idioma_id":5,"titulo":"Diagrama de fases experimental Fe-Sn-Zr. Nuevos resultados del corte isotérmico de 800°C","resumen":"Las aleaciones de base Zr son de extendida aplicación en el campo de la tecnología nuclear. El Zr aleado con Sn y Fe es la base principal de las aleaciones tipo Zircaloy, aún hoy muy utilizadas como elementos estructurales y como contenedores de los elementos combustibles en reactores nucleares de potencia. Este sistema metalúrgico ternario también forma parte de aleaciones de más reciente desarrollo como las Zirlo (EEUU). Si bien en todas ellas el Zr es el aleante mayoritario es útil e importante conocer los diagramas de fases de sus componentes en la forma más completa posible.El diagrama de fases Fe-Sn-Zr viene siendo estudiado en forma sistemática por el grupo de trabajo desde hace años. Se ha avanzado mucho en el trazado del diagrama de fases a 800ºC, pero han quedado regiones del triángulo de Gibbs sin resolver. Con el objeto de evaluar experimentalmente estas zonas se procedió al diseño y fabricación de un conjunto de aleaciones ternarias. Las mismas fueron tratadas térmicamente a la temperatura de interés por 2928 horas y caracterizadas aplicando técnicas de metalografía, difracción de rayos X y de microanálisis. En este trabajo se confirmó la existencia de los compuestos ternarios Y y Fe6Sn6Zr, así como la presencia de la fase X? y se determinaron campos de existencia de 2 y 3 fases, todo a 800°C. Finalmente se trazaron los límites de equilibrio de fases en las regiones bajo estudio, completando en gran proporción el diagrama de fases para el corte isotérmico analizado.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239634,"idioma_id":5,"titulo":"El atroz encanto de ser argentinos","resumen":"Reflexión sobre el consumo y la generación de electricidad en la Argentina, de cara al cuadragésimo quinto aniversario de la Conferencia de Estocolmo&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239640,"idioma_id":4,"titulo":"Possible Selves in Adolescence: Development and validation of a Scale for their Assessment","resumen":"Possible selves (PSs) have a significant role in adolescents? development. For this reason, it is of great importance to have adequate measures to operationalize them. The aim of this work is to present the construction and validation of a scale to assess PSs at the end of high school in multiple domains. Participants were adolescents (n = 320) of both sexes (female = 51.3%) from high-schools in Buenos Aires City, Argentina (age, M = 14.9, SD = 1.5). The scale was developed based on a literature review and a previous qualitative study. Expert judges? assessment revealed that it has good content validity. The scale?s structure was studied with exploratory factor analysis and a 5-factor structure with theoretical meaning was found. Spearman?s correlations between current and future self-perceptions show evidence of convergent validity. Mann-Whitney U test shows that the scale can discriminate by sex and age. The scale shows from adequate to very good internal consistency. This These results show that the scale has adequate psychometric properties to assess PSs in Argentine adolescents.  The advantages of this scale respect relative to existing measures of PSs are discussed. Scale development allows us to know more about how adolescents think they will be during a The scale develop allows to know how adolescents think they will be into a significant life transition such as the end of high school. This is particularly important for planning interventions focus on motivation and behavior regulation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239656,"idioma_id":5,"titulo":"Los posibles sí mismos de los adolescentes de Buenos Aires","resumen":"El objetivo de este trabajo fue explorar y describir los posibles sí mismos (PSs) de un grupo de adolescentes de la Ciudad de Buenos Aires (CABA). Participaron de este estudio 72 adolescentes (69.4% mujeres) de una escuela privada de la CABA (M = 15.04; DE = 1.56). Los adolescentes respondieron un cuestionario de preguntas abiertas en el que se les pidió que realicen un listado de sus PSs cuando terminen el secundario. Se realizó un análisis de contenido temático de las respuestas y un conteo de frecuencias de las categorías. Los adolescentes generaron PSs en cinco grandes áreas: personal,  académico\/ocupacional, física, social, y de satisfacción y logros. El área más prevalente es la académico\/ocupacional. La mayoría de los adolescentes generaron PSs en una o dos áreas. Indexación: Thomson Reuters, Scielo, EBSCO, Redalyc, Publindex (Cat A2), Latindex, CLASE, BVS, Dialnet, CLACSO, e-revistas, DOAJ, HAPI, MAIR, CARHUS Plus, entre otras.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239657,"idioma_id":5,"titulo":"[EN EVALUACION] Validez y fiabilidad de la Escala de Promoción de Desafíos por parte de los Padres y su contribución en el flow de deportistas adolescentes de Selecciones Nacionales Argentinas","resumen":"El propósito de este trabajo es presentar las propiedades psicométricas de la Escala de Promoción de desafíos por parte de los padres en deportistas de alto rendimiento y evaluar la contribución de esta variable en la experiencia óptima (flow) de estos adolescentes. Participaron 276 adolescentes de entre 11 y 19 años de edad (M = 15.71; DT = 1.49) pertenecientes a las Selecciones Nacionales Argentinas de diferentes deportes. El 54% eran varones (n = 149) y el 46% mujeres (n = 127), quienes respondieron un cuestionario socio-demográfico, la Escala de Promoción de Desafíos por parte de los Padres (EPDP) y la Escala de experiencias óptimas (flow) para adolescentes. A través del Análisis Factorial Confirmatorio, Análisis del Componente de la Varianza y de Generalizabilidad se obtuvieron adecuados indicadores de validez y fiabilidad para la EPDP (GFI = .99; AGFI = .98; CFI = 1; RMSEA = 0.0; RMR = .06; SRMR = .06; G relativo = .82; G absoluto = .81). La promoción de desafíos contribuye al flow desde la dimensión del apoyo y solo tiene un peso significativo en el grupo de mujeres.Indexación: Scopus -  SCIELO - Thomson-ISI (Social SciSearch: Journal Citation Reports) - DICE ? Latindex - EBSCOhost ? PsycINFO - Psicodoc - ISOC Psicología ? entre otras","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239658,"idioma_id":5,"titulo":"La percepción de los estilos de crianza y su relación con las autopercepciones de los niños de Buenos Aires: Diferencias en función del género.","resumen":"El objetivo de este trabajo fue estudiar la influencia de la percepción de los estilos de crianza en las autopercepciones de los niños en función del género. Se administró el Perfil de Autopercepciones para Niños (SPPC) y la Escala Argentina de Percepción de la Relación con los Padres a una muestra de 98 niños de ambos sexos (varones 43.90%; edad media= 9.86; DE= 1.28) de Buenos Aires (Argentina). Se encontró que la percepción de la relación con los padres predice el nivel de las autopercepciones de las niñas en los todos los dominios evaluados (físico\/social, académico\/comportamental, y autoestima global) mientras que sólo la aceptación por parte de la madre predice las autopercepciones de los varones en el dominio físico\/social.   Indexación: ISI (Thomson Reuters Social Science Citation Index) - Scopus -APA PsycInfo - Index Copernicus - DOAJ (Directory of Open Access Journals) - SciELO - PEPSIC - Clase - Latindex -Psicodoc - Dialnet - Biblioteca Virtual en Salud Psicología - Redalyc - Georgetown University - Infomotions Inc. - Journal Info - UNC University - Arizona Health Science Library - British Library - Cornell University Library","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239662,"idioma_id":4,"titulo":"Hydrochemical characterization of water resources in the santa maría Valley, NW of Argentina","resumen":"Hydrochemical researches in Santa M María Valley located in Catamarca and Tucumán in tthe northwest of Argentina were carried out to assess the chemical cha racteristics of surface water and groundwater, to und derstand the sources of dissolved ions by defining the principal hydroc chemical processes in order to provide theoretical b bases to developing strategies of natural resources uses in the region. T This region is dominated by a semi-arid climate. A to otal of twenty five water samples have been collected. The physicochem mical parameters determined in water by standardi ized methods werepH, electrical conductivity (EC), major ions (calcium m, magnesium, sodium, potassium, chloride, sulphate, carbonate and bicarbonate) and Total Dissolved Solids (TDS). Accordiing to the Piper diagram, the region mainly containss Na-Ca?HCO3 followed by Na­HCO3-Cl, Ca-Na-HCO3-SO4 and Mg--Ca-Na-HCO3 water types. The contents of sodium, , calcium, magnesium, chloride, sulphate and bicarbonatein the waters of the area areexplained by the dissolution of halite, c calcite, dolomite and gypsum and other reactions like cation exchange an nd weathering of minerals of basement rocks.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239663,"idioma_id":5,"titulo":"No aceleremos la muerte térmica del Universo","resumen":"artiendo de la premisa de que la educación aparece como la única alternativa viable para modificar conductas y valores, que permitan frenar el consumo y, con ello, demandar menor cantidad de recursos naturales; en esta nota se describe el paso de la educación ambiental a la educación para el desarrollo sostenible y los conceptos de sostenibilidad y entropía.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239668,"idioma_id":5,"titulo":"La estetización de la existencia como proyecto superador de la muerte de dios en la filosofía de Friedrich Nietzsche","resumen":"El artículo se propone tematizar la concepción de ?estética de la existencia? en la filosofía de Friedrich Nietzsche. Para ello, en la primera parte se aborda la crítica nietzscheana a la metafísica occidental y su impacto en la subjetividad, luego se analiza el fenómeno del nihilismo y sus efectos, y finalmente se examinan los conceptos de ?máscara?, ?metáfora? y ?actor? para lograr concebir un posible proyecto nietzscheano de estetización de la existencia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239670,"idioma_id":5,"titulo":"Oligodoncia congénita sindrómica: descripción de un caso clinico","resumen":"RESUMENLa ausencia congénita de elementos dentarios o agenesia se presenta con mayor frecuencia en la dentición permanente y es poco frecuente observarla en la dentición temporaria. Dentro de la clasificación de agenesias, debemos considerar dos variantes que incluyen: la hipodoncia, que comprende la agenesia de menos de 6 elementos permanentes, y la oligodoncia, o agenesia de 6 o más elementos dentarios permanentes. En ningún caso se incluye la agenesia de terceros molares. Si bien la agenesia de un elemento dentario se observa con frecuencia en la clínica o como hallazgo radiográfico, la presencia de oligodoncia, por el contrario, es una anormalidad poco frecuente que afecta el 0.1 al 0.3% de la población. La oligodoncia puede constituir una anomalía no sindrómica, la cual puede ser un evento esporádico o manifestarse en forma familiar de herencia autosómica dominante, recesiva o ligada a X. Lo más frecuente es que la oligodoncia sea parte de un síndrome que incluye la agenesia dental y la anormalidad de otros órganos o tejidos. Presentamos a continuación un caso clínico con agenesias dentarias múltiples de tipo sindrómico y analizamos posibles diagnósticos diferenciales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239672,"idioma_id":4,"titulo":"Lateral Antimicrobial Resistance Genetic Transfer is active in the open environment","resumen":"Altmetric: 14More detailArticle | OPENLateral Antimicrobial Resistance Genetic Transfer is active in the open environmentLuciana S. Chamosa, Verónica E. Álvarez, Maximiliano Nardelli, María Paula Quiroga, Marcelo H. Cassini & Daniela CentrónScientific Reports 7, Article number: 513 (2017)doi:10.1038\/s41598-017-00600-2Download CitationAntimicrobial resistanceMicrobial ecologyReceived:28 October 2016Accepted:27 February 2017Published online:31 March 2017AbstractHistorically, the environment has been viewed as a passive deposit of antimicrobial resistance mechanisms, where bacteria show biological cost for maintenance of these genes. Thus, in the absence of antimicrobial pressure, it is expected that they disappear from environmental bacterial communities. To test this scenario, we studied native IntI1 functionality of 11 class 1 integron-positive environmental strains of distant genera collected in cold and subtropical forests of Argentina. We found natural competence and successful site-specific insertion with no significant fitness cost of both aadB and blaVIM-2 antimicrobial resistance gene cassettes, in a model system without antibiotic pressure. A bidirectional flow of antimicrobial resistance gene cassettes between natural and nosocomial habitats is proposed, which implies an active role of the open environment as a reservoir, recipient and source of antimicrobial resistance mechanisms, outlining an environmental threat where novel concepts of rational use of antibiotics are extremely urgent and mandatory.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239675,"idioma_id":4,"titulo":"Growth during recovery evidences the waterlogging tolerance of forage grasses","resumen":"Waterlogging is a stress of increasing importance for pastures as a consequence of global climate change. Weevaluated the impact of waterlogging on four forage grasses with alleged differential tolerance, emphasising not onlyresponses during the stress but also their reported ability to recover from it. To do this, 42-day plants of Dactylis glomerata,Bromus catharticus, Festuca arundinacea and Phalaris aquatica were subjected to 15-day waterlogging, followed by asubsequent 15-day recovery period. Shoot and root growth (i.e. RGR) during both periods, in addition to net photosynthesisand stomatal conductance rates during waterlogging were assessed. Sensitivity exhibited by D. glomerata and B. catharticusduring waterlogging was related to growth arrest of roots ? but not of shoots ? along with a progressive fall in stomatalconductance and net photosynthesis. The injury during waterlogging preceded a negligible growth of shoots and roots, onlyevident during recovery in both species. By contrast, P. aquatica exhibited unaltered root RGR and promoted shoot RGRwith no impact on leaf gas exchange during waterlogging; whereas F. arundinacea showed intermediate tolerance asroot RGR was reduced during waterlogging, with stomatal conductance, net photosynthesis and shoot RGR remainingunaffected. These latter two species fully regained shoot and root RGR during recovery. So, P. aquatica and F. arundinaceaseem more suitable for prone-to-flood lowlands, whereas to be conclusive about waterlogging tolerance, it is necessary toexamine plant recovery as shown in D. glomerata and B. catharticus.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239676,"idioma_id":4,"titulo":"No escape? Costs and benefits of leaf de-submergence in the pasture grass Chloris gayana under different flooding regimes","resumen":"Elongation-induced leaf emergence is one way for plants to deal with completesubmergence by ?escaping? from water. This growth strategy is hypothesized to be more beneficial under single long-term submergence than under repeated short-term submergence events (i.e. fluctuating environment), as costs of repeated plant ?adjustment? would exceed the initial benefits of shoot elongation. To test this idea, 2-week-old plants of Chloris gayana cv. Fine Cut (a submergence-tolerant cultivar firstly selected by a screening experiment) were grown for 4 weeks under (i) control conditions, (ii) two 1-week submergence cycles, or (iii) one 2-week submergence cycle. Additionally, a set of plants were placed below nettings to assess the cost of remaining forcedly submerged. Impeding leaves emergence through nettings did not compromise survival when submergence was 1-week long, but determined the death of all plants when extended to 2 weeks. Growth as affected by flooding regime revealed that under one 2-week submergence event, plants accumulated a 2.9-fold higher dry mass than when they experienced the same submergence duration in separate events along 1week. The ?escape? strategy in the grass C. gayana, by which leaf contact with air is reestablished, is essential for its survival, and it is more beneficial for plant growth under long-term submergence than under repeated short-term submergence cycles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239678,"idioma_id":4,"titulo":"Synthesis and characterization of chitosan membranes functionalized with amino acids and copper for adsorption of endoglucanase","resumen":"Chitosan membranes were obtained and functionalized with amino acids and copper in order to improve adsorption selectivity of endoglucanase. The membranes were characterized by Fourier-transformed infrared spectroscopy with attenuated total reflectance device (FTIR-ATR) to monitor chemical changes. Scanning electron microscopy (SEM) was performed to compare the surface morphology of the membranes. Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) were carried out in order to analyze thermal stability of functionalized membranes and to identify the differences between functionalized chitosan membranes before and after endoglucanase adsorption. SEM results proved that functionalization had occurred since the surface of the chitosan membrane was modified. FTIR-ATR results confirmed an effective chemical modification of chitosan membranes with amino acids and copper and corroborated endoglucanase adsorption. The characteristic parameters of DSC and TGA also evidenced endoglucanase adsorption. The use of functionalized membranes as adsorbents increased 40-fold the percentage of endoglucanase adsorption as compared to unmodified membranes. Thus, chitosan membranes functionalized with amino acids and copper may represent a novel, low-cost adsorbent to be used in endoglucanase purification from complex systems.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239682,"idioma_id":4,"titulo":"Enhancing edaphoclimatic zoning by adding multivariate spatial statistics to regional data","resumen":"..","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239683,"idioma_id":5,"titulo":"Presupuestos epistemológicos  y enseñanza del derecho administrativo","resumen":"El objeto de este trabajo es vincular las cuestiones epistemológicas presentes en la enseñanza del Derecho en las universidades, con especial referencia al Derecho Administrativo. En el artículo se consideran las ventajas de la explicitación de los presupuestos epistemológicos y valorativos de los docentes, así como los riesgos del ocultamiento habitual de estas cuestiones.  Finalmente, se formulan propuestas y conclusiones para hacer más transparente la existencia e importancia de los factores ideológicos y políticos en juego en la enseñanza del Derecho Público.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239689,"idioma_id":5,"titulo":"Desempeño de los ingresantes","resumen":"El presenta artículo se basa en el Proyecto de Investigación denominado 'Curso de articulación, Olimpíadas en Ciencias Económicas y Propedéutico e Introducción a la teoría contable de la carrera de Contador Público de la Facultad de Ciencias Económicas UNER'. Este proyecto pretende relacionar los resultados en exámenes parciales y finales realizados por los alumnos de la Cátedra de Introducción a la Teoría Contable, luego de haber cursado y aprobado el Curso de Articulación o Propedéutico y haber participado en las Olimpíadas en Ciencias Económicas.La inquietud de relacionar todas estas actividades con el rendimiento en la cátedra, trata de establecer si existen diferencias en los resultados de las evaluaciones, según se haya participado o no de los cursos mencionados","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239693,"idioma_id":5,"titulo":"La Televisión Digital Terrestre. Situación actual y Tendencias de futuro. Colegio Oficial de Ingenieros de Telecomunicación.","resumen":"BRON, Maximiliano. La Televisión Digital Terrestre. Situación actual y Tendencias de futuro. Colegio Oficial de Ingenieros de Telecomunicación.. Revista ICONO14 Revista científica de Comunicación y Tecnologías emergentes, [S.l.], v. 15, n. 2, p. 1-2, jul. 2017. ISSN 1697-8293. Disponible en: . Fecha de acceso: 15 sep. 2017 doi: https:\/\/doi.org\/10.7195\/ri14.v15i2.1087.ABNT","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239694,"idioma_id":5,"titulo":"Conocimiento y acción: Integralidad de las funciones universitarias y emprendedorismo","resumen":"El presente artículo pretende difundir las acciones desarrolladas en el marco del Proyecto de Integralidad denominado 'La integración de docencia, extensión e investigación mediante prácticas sociales con emprendedores' llevado adelante por un grupo de docentes, extensionistas e investigadoras de la Facultad de Ciencias Económicas de la Universidad Nacional de Entre Ríos (UNER).Este proyecto, que articula docencia, investigación y extensión, tiene como objetivo conocer a los emprendedores de la Economía Social vinculados con la Facultad y elaborar en forma conjunto con este colectivo alternativas para el fortalecimiento de su gestión al tiempo de producir información sobre el mismo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239695,"idioma_id":5,"titulo":"El caso del Proyecto transdisciplinario DTEC-UNSE.  Resultados del primer año","resumen":"En el marco de una convocatoria de la Agencia la Universidad Nacional de Santiago del Estero presentó un proyecto con el título de ?Diseño de procesos alternativos de transferencia tecnológico\/productiva hacia sistemas de producción complejos (sistemas de producción de la Agricultura Familiar)?; un proyecto transdisciplinario formado por 20 profesionales de diferentes áreas, tanto de las ciencias exactas, naturales como sociales. La importancia y originalidad del proyecto reside en dos puntos clave que constituyen su fortaleza: en primer lugar el trabajo con representantes de la agricultura familiar, dando respuesta a sus necesidades; y en segundo lugar, el trabajo transversal que se realiza entre los profesionales miembros del equipo que permite tener una mirada amplia sobre cada sistema productivo, de manera que el mejoramiento en un área no implica dejar de lado otros aspectos importantes del sistema.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239696,"idioma_id":4,"titulo":"Target-site resistance to acetolactate synthase (ALS)-inhibiting herbicides in Amaranthus palmeri from Argentina","resumen":"BACKGROUND: Herbicide-resistant weeds are a serious problem worldwide. Recently, two populations of Amaranthus palmeri with suspected cross-resistance to acetolactate synthase (ALS)-inhibiting herbicides (R1 and R2) were found by farmers in two locations in Argentina (Vicuña Mackenna and Totoras, respectively). We conducted studies to confirm and elucidate the mechanism of resistance. RESULTS: We performed in vivo dose?response assays, and confirmed that both&nbsp; populations had strong resistance to chlorimuron-ethyl, diclosulam and imazethapyr when compared with a susceptible population (S). In vitro ALS activity inhibition tests only indicated considerable resistance to imazethapyr and chlorimuron-ethyl, indicating that other non-target mechanisms could be involved in diclosulam resistance. Subsequently, molecular analysis of als nucleotide sequences revealed three single base-pair mutations producing substitutions in amino acids previously associated with resistance to ALS&nbsp; inhibitors, A122, W574, and S653. CONCLUSION: This is the first report of als resistance alleles in A. palmeri in Argentina. The data support the involvement of a target-site mechanism of resistance to ALS-inhibiting herbicides.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239697,"idioma_id":4,"titulo":"In Vitro Human Umbilical Vein Endothelial Cells Response to Ionic Dissolution Products from Lithium-Containing 45S5 Bioactive Glass","resumen":"Since lithium (Li+) plays roles in angiogenesis, the localized and controlled release of Li+ ions from bioactive glasses (BGs) represents a promising alternative therapy for the regeneration and repair of tissues with a high degree of vascularization. Here, microparticles from a base 45S5 BG composition containing (wt %) 45% SiO2, 24.5% Na2O, 24.5% CaO, and 6% P2O5, in which Na2O was partially substituted by 5% Li2O (45S5.5Li), were obtained. The results demonstrate that human umbilical vein endothelial cells (HUVECs) have greater migratory and proliferative response and ability to form tubules in vitro after stimulation with the ionic dissolution products (IDPs) of the 45S5.5Li BG. The results also show the activation of the canonical Wnt\/â-catenin pathway and the increase in expression of proangiogenic cytokines insulin like growth factor 1 (IGF1) and transforming growth factor beta (TGFâ). We conclude that the IDPs of 45S5.5Li BG would act as useful inorganic agents to improve tissue repair and regeneration, ultimately stimulating HUVECs behavior in the absence of exogenous growth factors.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239699,"idioma_id":5,"titulo":"ARAN-NOR","resumen":"El proyecto está destinado a desarrollar productos farmacéuticos con extractos de arándanos, y promover consumo de los mismos por las excelentes propiedades antioxidantes. Nuestro grupo de trabajo viene estudiando frutos cultivados en el NOA comprobando el contenido de componentes fisiológicamente activos. Las investigaciones y desarrollo farmacéutico tienden a convertir el concepto de un nuevo medicamento en realidad, desarrollando fórmulas estables que tengan ventajas comparativas en el mercado global. Para ello se realizan caracterizaciones fisicoquímicas y biológicas de los nuevos productos, desarrollando métodos analíticos exactos y precisos para la cuantificación de los principios activos y excipientes, evaluando cada formulación expuesta a diferentes condiciones de temperatura y humedad (estudios de estabilidad), los que ofrecen un alto estándar de calidad para los productos. En nuestra provincia la producción de frutos finos está creciendo en forma sostenida y el desarrollo de productos farmacéuticos con arándanos podría fortalecer de la cadena de comercialización.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239700,"idioma_id":5,"titulo":"QUIN-TUC","resumen":"El proyecto está destinado a crear conciencia sobre la importancia de la quinoa, revalorizándola para emplearla en la producción de productos farmacéuticos y\/o alimentos.Nuestro grupo de trabajo viene estudiando semillas andinas comprobando el contenido de componentes fisiológicamente activos. El desarrollo de QUIN-TUC se efectúa a partir de extractos de quinoa, optimizando el aprovechamiento de componentes antioxidantes, fibra dietética que pueden contribuir en la prevención enfermedades. Teniendo en cuenta estas propiedades químicas y biológicas es factible el desarrollo de un nutracéutico de alta calidad y bajo costo para la prevención y tratamiento de algunas patologías.En nuestro país la producción de granos andinos como la quinoa está creciendo en forma sostenida, siendo necesario agregar valor agregado esta materia prima a nivel regional, impulsando el desarrollo sustentable del cultivo, con fortalecimiento de la cadena de comercialización.Palabras claves: quinoa, nutracéuticos, desarrollo de producto","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239701,"idioma_id":5,"titulo":"Aprendizaje autorregulado en el nivel universitario: Un estudio situado con estudiantes de psicopedagogía de diferentes ciclos académicos","resumen":"Ser capaz de autorregular adecuadamente el propio aprendizaje impacta positivamente en el rendimiento académico del alumnado. De aquí la relevancia de entender cuáles son, cómo se articulan y cómo cambian estrategias de aprendizaje y patrones de motivación en el transcurso de la formación académica. Los objetivos de este trabajo son: (a) describir estrategias cognitivas\/metacognitivas de aprendizaje y patrones de motivación usadas por estudiantes (media y desviación estándar); (b) analizar las correlaciones entre ambos grupos de variables (correlación índice de Pearson); (c) contrastar resultados según Ciclo Básico (1° año) y Superior (5° año) de formación académica (prueba de hipótesis t de Student). El estudio cuantitativo ex post facto se basó en la administración de la versión argentina del MSLQ (Motivated Strategies Learning Questionnaire) denominada MSLQe a 114 estudiantes de psicopedagogía. Los resultados muestran: (a) un repertorio variado de estrategias y patrones de motivación para el aprendizaje; (b) un mayor uso de estrategias metacognitivas de autorregulación y estrategias de manejo del tiempo y ambiente de estudio se asoció a altos niveles en los patrones motivacionales de orientación a metas, valoración de la tarea, creencias de control y de autoeficacia del estudiantado; (c) diferencias significativas según el ciclo académico: a favor del alumnado principiante en estrategias cognitivas de repaso, autorregulación metacognitiva y organización; mientras que las puntuaciones fueron superiores para los alumnos y las alumnas avanzadas en relación a pensamiento crítico. Asimismo, respecto de los patrones de motivación, los grupos avanzados declararon mayores tendencias hacia metas de orientación intrínsecas, mientras que los principiantes lo hicieron en metas de motivación extrínsecas, creencias de control, de autoeficacia y ansiedad. Es posible concluir que la formación académica posibilitó una integración jerárquica tanto de estrategias superficiales y profundas, así como de patrones de motivación internos y externos del estudiantado. De este modo, este artículo contribuye a un análisis de dimensiones cognitivas (frías y cálidas) como contextualmente situado (niveles iniciales y finales de la formación académica) de las estrategias de aprendizaje y patrones de motivación de grupos universitarios de estudiantes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239702,"idioma_id":4,"titulo":"Inactivation of Aspergillus carbonarius and Aspergillus flavus in malting barley by pulsed light and impact on germination capacity and microstructure","resumen":"The impact of pulsed light (PL) fluence on reduction of Aspergillus carbonarius and Aspergillus flavus conidia in barley grains (aw 0.60 and 0.98), germinability and structure was studied. Treatments were done for 5?75 s at 5 and 10 cm distance from the flash lamp (fluence: 11.0?165.8 J\/cm2 at 5 cm, and 6.0?89.6 J\/cm2 at 10 cm). Maximum reduction in fungal population was 1.2?1.7 log cycles up to 5?15 s (fluence: 6.0?18.0 J\/cm2). Acceptable germinability values were obtained up to 25 s treatment at 10 cm distance. Light microscopy study supported changes in germinability. Most of the structure elements of the caryopsis were drastically altered with high fluence values, while embryo viability was maintained with doses up to 29.9 J\/cm2. PL up to 18.0 J\/cm2 could be a nonchemical option to reduce moulds in barley with minor impact on germinability.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239703,"idioma_id":4,"titulo":"Taxonomic status of Wiedomys marplatensis, an enigmatic fossil cricetid (Rodentia, Sigmodontinae): neither Wiedomys nor Wiedomyini","resumen":"The generic placement and tribal affiliation of Wiedomys marplatensis Quintana, 2002 are revised based on the study of its holotype and a single known remains from San Andrés Formation (Early Pleistocene; Buenos Aires Province, Argentina). The anatomical traits selected as indicators belonging to Wiedomys Hershkovitz, 1959 are interpreted here as general similarities. Wiedomys marplatensis is removed from Wiedomys and is considered as a junior synonym of Cholomys pearsoni Reig, 1980. The affiliation of the latter to Wiedomyini is discussed and the alternative hypothesis to allocate Cholomys Reig, 1980 in Oryzomyini is advanced. Although further research and more fossils are necessary to solve this issue, the placement of Cholomys as Sigmodontinae incertae sedis and the avoidance of using it as a point of calibration in molecular phylogenies are suggested.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239704,"idioma_id":5,"titulo":"Sindicalismo y Trabajo docente. Temas en debate","resumen":"Este artículo introductorio al dossier sobre ?Sindicalismo y trabajo docente? plantea las motivaciones que han dado lugar al surgimiento de los estudios sobre asociaciones gremiales docentes, dando lugar a la conformación de un campo de conocimiento y una comunidad de investigadores. Desarrolla algunas de las principales problemáticas específicas: la relación entre la identidad docente y las prácticas sindicales;  la heterogeneidad del gremio como elemento de tensión interna; el proceso de trabajo y la posición social de la docencia como determinantes de la actividad sindical; el papel del sindicalismo en la política educativa;  la relación entre el sindicalismo docente y las reformas tecnocráticas aplicadas con las políticas neoliberales; la vida interna de las organizaciones sindicales; el sindicato como actor del sistema político; y los procesos de movilización y los sindicatos como movimientos sociales. Finalmente, presenta los artículos que componen el dossier.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239705,"idioma_id":5,"titulo":"Lo sexual es político: invectiva y potencia performativa del insulto en Catulo","resumen":"En el corpus catuliano, la invectiva y la flagitatio parecen poseer unsustrato común: los comportamientos criminales que son denunciados en lospoemas (robos de toda índole y gravedad) parecen consecuencia de aquello quese convierte en el verdadero foco de los poemas: la operación condenatoria de lapasividad, el exceso y el adulterio que diseñan perfiles de masculinidadcensurables por oponerse a los principios rectores de la virtus romana. De estemodo, la potencia performativa del insulto pone en evidencia el protocolo sexualy las normativas sexo-genéricas propias de la matriz de inteligibilidad cultural de la época. La lectura que realizaremos propone pensar a estos poemas como actospolíticos de nominación social que, al denunciar construcciones éticasdesplazadas, infractoras de los valores tradicionales, crean simultáneamente unperfil ideal de ciudadano e imágenes de abyección que funcionan como su reverso.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239709,"idioma_id":5,"titulo":"Bioinoculación de Chloris gayana cv. Finecut con Pseudomonas tolaasii IEXb y Bacillus atrophaeus CN4: estudio preliminar en la Llanura Deprimida Salina de Tucumán, Argentina","resumen":"El uso de bioinoculantes presenta ventajas en la germinación y crecimiento vegetal, convirtiéndolos en una alternativa para favorecer la implantación e incrementar la producción de pasturas megatérmicas en el marco de la intensifiación de los sistemas ganaderos. El objetivo de este trabajo fue evaluar el efecto de la inoculación de Chloris gayana cv. Finecut con Pseudomonas tolaasii IEXb y Bacillus atrophaeus CN4 en campo. Se evaluarontres tratamientos: semillas de C. gayana cv. Finecut sin inocular (control); semillas inoculadas con P. tolaasii IEXb y semillas inoculadas con B. atrophaeus CN4. A los 21, 40 y 70 días después de la siembra (DDS), se obtuvo el peso seco de la biomasa aérea y radicular. La producción de biomasa aérea forrajera acumulada se realizó a los 70 DDS. La inoculación con Bacillus atrophaeus CN4 influyó positivamente en los cortes para producción de biomasa forrajera, pero ello no se tradujo en incrementos signifiativos de la producción acumulada. El tratamiento IEXb mostró resultados similares a los 40 DDS. La biomasa radicular no mostró diferencias signifiativas entre tratamientos. Los resultados obtenidos muestran la necesidad de realizar evaluaciones a largo plazo sobre el uso de bionoculantes en pasturas que incluyan la inflencia de diferentes concentraciones de inóculo y el estudio de distintas cepas de rizobacterias promotoras del crecimiento vegetal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239719,"idioma_id":4,"titulo":"Shiga Toxin-producing Escherichia coli (STEC) O22:H8 isolated from cattle reduces E. coli O157:H7 adherence in vitro and in vivo","resumen":"Problem addressed: Shiga toxin-producing Escherichia coli (STEC) are a group of bacteria responsible for food-associated diseases. Clinical features include a wide range of symptoms such as diarrhea, hemorrhagic colitis and the hemolytic uremic syndrome (HUS), a life-threatening condition.Objective: Our group has observed that animals naturally colonized with STEC strains of unknown serotype were not efficiently colonized with E. coli O157:H7 after experimental infection. In order to assess the basis of the interference, three STEC strains were isolated from STEC persistently-colonized healthy cattle from a dairy farm in Buenos Aires, Argentina.Methods and Results: The three isolated strains are E. coli O22:H8 and carry the stx1 and stx2d genes. The activatable activity of Stx2d was demonstrated in vitro. The three strains carry the adhesins iha, ehaA and lpfO113. E. coli O22:H8 formed stronger biofilms in abiotic surface than E. coli O157:H7 (eae+, stx2+) and displayed a more adherent phenotype in vitro towards HeLa cells. Furthermore, when both serotypes were cultured together O22:H8 could reduce O157:H7 adherence in vitro. When calves were intragastrically pre-challenged with 108 CFU of a mixture of the three STEC strains and two days later challenged with the same dose of O157:H7 438\/99, the shedding of the pathogen was significantly reduced.Conclusions: These results suggest that non-O157 STEC might compete with O157:H7 at the bovine recto-anal junction, making non-O157 carrying-calves less susceptible to O157:H7 colonization and shedding of the bacteria to the environment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239721,"idioma_id":5,"titulo":"El grabado y la talla directa como estrategias de dialogicidad en los textos visuales de los Artistas del Pueblo (1925-1935)","resumen":"Durante las primeras décadas del siglo XX se produjeron, en Argentina, debates acerca del concepto de ?lo nacional? que estuvieron vinculados con los cambios político-sociales que acontecían en el mundo. Enconsecuencia, en el campo artístico se produjeron también debates reformativos en torno al papel del artista y la función social del arte que terminaron por definir nuevas prácticas y nuevos procesos de institucionalización y anti-institucionalización a partir de los cuales se establecieron zonas tanto de intercambio como de conflicto entre los artistas y los ámbitos de legitimación. Situándonos en este contexto, en el siguiente trabajo nos aproximamos a la producción de los Artistas del Pueblo con el fin de analizar las formas de discusión con la Institución propuestas en su programa estético. Se sostiene que las estrategias de «dialogicidad» utilizadas por la agrupación frente a la lógica del «discurso autoritario» de la Academia y el Salón no se reducirían al «topic» de sus «textos» sino que también recaerían en el uso del grabado y la talla directa, tanto por tratarse de técnicas que privilegian la difusión masiva en circuitos no-hegemónicos como también, y por sobre todo, por los modos de producción sígnica que posibilitan. De esta manera, el siguiente trabajo pretende el objetivo último de aproximarse a las técnicas de producción desde un enfoque que destaque su rol en la cadena discursiva y no tan solo como una mera herramienta de producción.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239724,"idioma_id":5,"titulo":"os vaivenes entre la ganadería y la agricultura en la provincia de Buenos Aires: Un breve recorrido histórico.","resumen":"ta a los orígenes de la ganadería bonaerense, cuya evolución explicaría en parte laestructura socioeconómica nacional actual. Esta evolución histórica fue modelando lasrelaciones entre los diversos actores que componen la cadena productiva, y generandocambios en la agricultura y la ganadería. El proceso de agriculturización, en especial suúltima etapa, provoca transformaciones que dan lugar al reordenamiento de la actividadganadera reconfigurando el mapa productivo tradicional. La demanda de trabajo, losrequerimientos de capital fijo y circulante, y los precios relativos de las diferentesactividades influyeron tanto en la estructuración y desarrollo de la ganadería y laagriculturaen su etapa inicial, así como también en los procesos contemporáneos deagriculturización e intensificación de la producción, y las transformaciones asociadas aéstos.Este artículo, explora a través de diversas fuentes bibliográficas los vaivenes entre laganadería y la agricultura en la región pampeana, en particular en la provincia de BuenosAires, señalando algunas características productivas y económicas que influyen en losvínculos y desplazamientos entre las actividades. A partir de este análisis queda claro que laactual situación de la actividad ganadera no es más que el devenir de una serie de procesoshistóricos articulados con algunas variables económicas coyunturales, que al actuar sobreactividades que compiten por el uso del suelo, con tiempos de respuesta y flexibilidad muy diferentes, continúan transformando los sistemas productivos en la búsqueda de adaptarse alos nuevos escenarios.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239726,"idioma_id":4,"titulo":"Cattle landscape selectivity is influenced by ecological and management factors in a heterogeneous mountain rangeland","resumen":"Few studies addressing drivers of cattle selectivity focus on the combination of ecological (biotic and abiotic) and management factors such as rotational systems, paddock sizes and paddock shapes. As a consequence, it is difficult to prioritise management practices integrating information of different driving factors. In a heterogeneous mountain rangeland in Central Argentina we established a total of 419 square study plots of 1ha located in 18 paddocks with differing sizes, shapes and cattle grazing management. Plots were small samples of landscapes, covering all existing variability in vegetation and physiography. For each plot we estimated the annual cattle use, average seasonal cattle density, forage types and abiotic characteristics. We used general linear models to show that selectivity was mainly driven by biotic variables. Cattle selected landscapes dominated by short palatable plants, but the strength of this influence differed among paddocks. Selectivity was strongest in paddocks with low abundance of lawns dominated by short palatable plants and low annual stocking rate. As stocking rate and the availability of lawns increased, selectivity strength decreased. Abiotic variables had far less influence than biotic variables, showing that cattle tended to avoid rough landscapes with steep terrain in the wet-warm season; and to be attracted by permanent water sources during the dry-cold season. Seasonal stocking density and paddock size had no detectable influence on cattle selectivity and distribution. Paddock shape influenced distribution but not the strength of forage selectivity. We conclude that in our system, cattle selectivity is mainly driven by biotic factors, and the most effective methods of changing the consequent distribution pattern is by manipulating forage types and paddock shape. The role of stocking rate remains controversial as it was correlated with the proportion of lawns in the paddock.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239727,"idioma_id":5,"titulo":"ERYTHROSTEMON GILLIESII VAR. BURKARTIANA (FABACEAE), TAXÓN VÁLIDO PARA ARGENTINA Y SU PRESENCIA EN LA PROVINCIA DE SANTIAGO DEL ESTERO","resumen":"Se confirma a Erythrostemon gilliesii var. burkartiana como taxón válido para la flora de la República Argentina, y se registra su presencia por primera vez en la Provincia de Santiago del Estero. Hasta el momento esta variedad había sido mencionada solamente para el oeste de la Argentina en la Provincia de Mendoza y existían dudas respecto a su validez. De esta manera se amplía su distribución geográfica al noroeste de la Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239730,"idioma_id":5,"titulo":"EVALUACION DEL RIESGO AMBIENTAL DE PEQUEÑAS Y MEDIANAS INDUSTRIAS","resumen":"RESUMEN: Se elaboró una herramienta de evaluación del riesgo ambiental adaptada a pequeñas y medianas industrias. Se aplicó en industrias de diversos sectores\/rubros. Resultó adecuada para identificar los aspectos ambientales que requieren intervenciones a través de planes de mejora como un aporte a la implementación de programas de producción limpia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239733,"idioma_id":4,"titulo":"Ouabain protects human renal cells against the cytotoxic effects of Shiga toxin type 2 and Subtilase cytotoxin","resumen":"Hemolytic uremic syndrome (HUS) is one of the most common causes of acute renal failure in children. The majority of cases are associated with Shiga toxin (Stx)-producing Escherichia coli (STEC). In Argentina, HUS is endemic and presents the highest incidence rate in the world. STEC strains expressing Stx type 2 (Stx2) are responsible for the most severe cases of this pathology. Subtilase cytotoxin (SubAB) is another STEC virulence factor that may contribute to HUS pathogenesis. To date, neither a licensed vaccine nor effective therapy for HUS is available for humans. Considering that Ouabain (OUA) may prevent the apoptosis process, in this study we evaluated if OUA is able to avoid the damage caused by Stx2 and SubAB on human glomerular endothelial cells (HGEC) and the human proximal tubule epithelial cell (HK-2) line. HGEC and HK-2 were pretreated with OUA and then incubated with the toxins. OUA protected the HGEC viability from Stx2 and SubAB cytotoxic effects, and also prevented the HK-2 viability from Stx2 effects. The protective action of OUA on HGEC and HK-2 was associated with a decrease in apoptosis and an increase in cell proliferation. Our data provide evidence that OUA could be considered as a therapeutic strategy to avoid the renal damage that precedes HUS.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239741,"idioma_id":5,"titulo":"El impacto de la educación alimentaria nutricional en el embarazo: una revisión de las experiencias de intervención","resumen":"Pregnancy is a period of great nutritional vulnerability in awomen?s life, thus food and nutrition education (FNE) is a valuabletool for achieving healthy eating. The purpose of this studywas to review the impact of nutritional interventions designedfor healthy pregnant women. An analysis of the geographicaldistribution of 42 publications and the educational strategiesemployed was conducted. Effectiveness to generate changes inknowledge, eating attitudes and practices, promote an adequateweight gain and to prevent anemia was analyzed. Research fromAsia and those including a combination of multiple educationalstrategies such as written information, information and communicationtechnologies, workshops or discussion groups were themost prevalent. Interventions show favorable results when theyintend to achieve an increase in the level of knowledge, stimulatechanges in dietary patterns and prevent iron-deficiency anemiaby adherence to iron supplementation. Gestational weight gainwas also favorably affected when FNE is employed, however,the prevention of excessive weight gain depended on nutritionalstatus prior to pregnancy and on other genetic and environmentaldeterminants. Successful experiences encourage the inclusion ofFNE as a routine tool in prenatal care; personalized nutritionalcounselling and the use of ICT are alternatives of choice in thecurrent health scenario","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239746,"idioma_id":5,"titulo":"Contra la revolución: circulación cultural y discursos decadentistas en Argentina (1917-1922).","resumen":"En este trabajo se analiza la circulación de ideas, imágenes, productos periodísticos y editoriales sobre la revolución rusa en el universo político y cultural de las derechas. La tendencia decadentista propia de esta cultura política tenía distintas vertientes, entre las cuales se recorta el discurso católico por ser el de mayor difusión en este período. El trabajo partió de dos interrogantes centrales ¿qué significó la revolución rusa para la cultura decadentista? y ¿qué el lugar ocupó ésta en los orígenes de la cultura política nacionalista? Los autores que adherían al pensamiento decadentista vincularon la revolución a un conjunto de eventos inquietantes (locales e internacionales). Por lo tanto, la intertextualidad es una operación interpretativa clave para abordar los problemas planteados. De esta manera, el significado de los hechos revolucionarios fue cristalizando a partir de dos movimientos: la curiosidad por un fenómeno disruptivo producido en un país lejano y la vinculación (real o imaginaria) con otros hechos locales contemporáneos o posteriores a la Revolución vinculados a la cuestión social.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239747,"idioma_id":5,"titulo":"Andamiaje teórico-metodológico: propuesta desde una investigación en comunicación","resumen":"Entendemos a la investigación social como un proceso articulado donde se traman las perspectivas teóricas y metodológicas, ocupando ambas un papel fundamental para la construcción de nuestros objetos. El presente artículo aborda la propuesta del diseño teórico-metodológico para una investigación en comunicación. Para ello, en un primer momento sentaremos posición acerca de lo que comprende un estudio en comunicación desde los aportes de la comunicación\/educación y la semiótica. Luego, compartiremos las principales características de nuestro objeto de estudio. Finalmente, recorreremos el diseño metodológico construido para poder responder a los interrogantes planteados para la investigación de una práctica comunicativa ritualizada: los actos patrios en escuelas primarias públicas de la provincia de Misiones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239754,"idioma_id":4,"titulo":"Techno-economic assessment of biomass gasification of Spartina argentinensis","resumen":"Argentina has rangelands with high biomass production and low profitability such as the ?Bajos Submeridionales?, a depressed 33,000 km2 area most of it dominated by a perennial grass, Spartina argentinensis. We assessed the techno-economic feasibility of S. argentinensis pellets gasification for combined heat and power purposes. Energy balance was estimated obtaining an Energy Return On Investment (EROI) of 5.43. Breakeven energy price (BEPE) was calculated for: (i) business as usual (BAU) and (ii) alternative scenario (AS) considering international natural gas price of 0.2 and 0.47 USD.m-3 respectively. Investment net present value (NPV) was calculated and a sensitivity analysis were performed. BEPE resulted 142.8 and 115.7 USD.MWeh-1 for BAU and AS respectively. NPV was ?3.6 and -0.3 million dollars for BAU and AS respectively showing the relevance of natural gas price on economic results. Power efficiency and electricity selling price were the variables with higher impact on NPV","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239755,"idioma_id":5,"titulo":"Organizaciones y subsidios estatales en Mendoza, Argentina (2009-2012)","resumen":"El objetivo de este artículo es ofrecer una lectura de las relaciones entre las organizaciones y el Estado en la Argentina. Está basado en un estudio de caso realizado en barrios populares de la ciudad de Mendoza entre 2009 y 2012. Primero, presento los cambios en las políticas sociales durante los últimos veinte años. Luego, describo las relaciones entre organizaciones y funcionarios y el uso de clasificaciones oficiales. Posteriormente, detallo cómo la percepción de subsidios estatales ha modificado los vínculos entre los integrantes de las organizaciones. Finalmente, reflexiono sobre sus posibilidades y límites en la ejecución de programas sociales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239762,"idioma_id":4,"titulo":"Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection","resumen":"The parasite Trypanosoma cruzi is the causative agent of Chagas disease, a potentially life-threatening infection that represents a major health problem in Latin America. Several characteristics of this protozoan contribute to the lack of an effective vaccine, among them: its silent invasion mechanism, T. cruzi antigen redundancy and immunodominance without protection. Taking into account these issues, we engineered Traspain, a chimeric antigen tailored to present a multivalent display of domains from key parasitic molecules, combined with stimulation of the STING pathway by c-di-AMP as a novel prophylactic strategy. This formulation proved to be effective for the priming of functional humoral responses and pathogen-specific CD8+ and CD4+ T cells, compatible with a Th1\/Th17 bias. Interestingly, vaccine effectiveness assessed across the course of infection, showed a reduction in parasite load and chronic inflammation in different proof of concept assays. In conclusion, this approach represents a promising tool against parasitic chronic infections.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239763,"idioma_id":5,"titulo":"El ejército y la guerra en la construcción de la cohesión. El caso de los visigodos: siglo V y comienzos del VI","resumen":"El presente trabajo tiene como objetivo abordar la problemática de la construcción de la cohesión social en el contexto del reino visigodo. Para ello, abordaremos ejemplos correspondientes al accionar de esta gens desde su instalación en la Galia, en primer lugar, como así también en el marco de las campañas militares del imperio romano tardío y durante el siglo VI ?momento en que se consolida el regnum, primero en Galia y luego en Hispania?. En este sentido, analizaremos las instancias por las cuales los visigodos lograban construir y consolidar la citada cohesión, en relación con las actividades militares en las que participaban.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239764,"idioma_id":4,"titulo":"Aldehyde-hydrate equilibrium in nucleobase 2-oxoethyl derivatives: An NMR, ESI-MS and theoretical study","resumen":"AbstractN-2-oxoethyl derivatives of nucleobases are useful starting materials for the preparation of potentially active nucleoside analogues. The 1HNMR, 13CNMR, DEPT and ESI-MS spectra of adenine and thymine N-2-oxoethyl derivatives reveal that the different species in equilibrium exist mainly in two forms: aldehyde and hydrate. The NMR spectra show that the equilibrium is shifted towards the hydrate form in water-DMSO 2:1, giving equilibrium constants of 8.3 and 5.3 for adenine and thymine derivatives, respectively. ESI-MS experiments show the dependence of equilibrium shift on pH: in the case of the thymine derivative, the effect on the equilibrium is more important than in the case of the adenine derivative; this difference is explained considering different protonation sites in both structures. All assumptions are supported by theoretical calculations, which suggest the important role played by solvent in the stabilization of molecular structures and equilibrium shift. All aspects analyzed in this work are very important in order to understand the further reactivity of these nucleobase derivatives.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239765,"idioma_id":4,"titulo":"Pd and In addition onto Au nanoparticles supported on TiO2 as&nbsp;a catalytic formulation for NO3 &minus; reduction in water","resumen":"The catalytic performance of Pd?In?Au\/TiO2 was studied for the reduction of nitrites and nitrates in water and compared with that of Au, Pd, Pd?In, In?Au and Pd?Au supported on TiO2. Different characterization techniques were used to study the bulk and surface physicochemical properties of the trimetallic catalyst. The catalyst so obtained was active and stable in the nitrate reduction reaction, having a good selectivity to nitrogen. This improvement caused by the presence of gold is attributable to a strong interaction with surface palladium and can therefore act to regulate the hydrogenation activity of the Pd particles. Over 80% of Pd is deposited on top of the Au nanoparticles, which interact with surface Au during the reduction process. The NO2 &#8722; species is an intermediate product in the NO3 &#8722; reduction and the surface In?Pd intermetallic species are responsible for this first reaction step.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239766,"idioma_id":4,"titulo":"Sesquiterpene lactones from Mikania species display activity against Trypanosoma cruzi and Leishmania sp.","resumen":"Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of Mikania variifolia and Mikania micrantha dichloromethane extracts. Mikanolide and deoxymikanolide were the major compounds in both extracts (2.2% and 0.4% for Mikania variifolia and 21.0% and 6.4% for Mikania micrantha respectively, calculated on extract dry weight). Mikanolide, deoxymikanolide and dihydromikanolide were active against Trypanosoma cruzi epimastigotes (50% inhibitory concentrations of 0.7, 0.08 and 2.5 µg\/ml, for each compound respectively). These sesquiterpene lactones were also active against the bloodstream trypomastigotes (50% inhibitory concentrations for each compound were 2.1, 1.5 and 0.3 µg\/ml, respectively) and against amastigotes (50% inhibitory concentrations for each compound were 4.5, 6.3 and 8.5 µg\/ml, respectively). By contrast, scandenolide was not active on Trypanosoma cruzi. Besides, mikanolide and deoxymikanolide were also active on Leishmania braziliensis promastigotes (50% inhibitory concentrations of 5.1 and 11.5 µg\/ml, respectively).The four sesquiterpene lactones were tested for their cytotoxicity on THP 1 cells. Deoxymikanolide presented the highest selectivity index for trypomastigotes (SI = 54) and amastigotes (SI=12.5). In an in vivo model of Trypanosoma cruzi infection, deoxymikanolide was able to decrease the parasitemia and the weight loss associated to the acute phase of the parasite infection. More importantly, while 100% of control mice died by day 22 after receiving a lethal T. cruzi infection, 70% of deoxymikanolide-treated mice survived. We also observed that this compound increased TNF-&#945; and IL-12 production by macrophages, which could contribute to control T. cruzi infection.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239767,"idioma_id":4,"titulo":"Microreactor with copper oxide nanostructured films for catalytic gas phase oxidations","resumen":"Three simple gas phase based methods were applied to copper foils with parallel microchannels to induce in-situ growth of nanostructured CuOx films. One method consisted in treating with vapors of NH4OH and H2O2 (VAP); another method consisted in heating in air at 500°C (CAL); and the third one was a sequence of both methods (CAL-VAP). The synthesized CuOx films\/Cu foils were assembled as microreactors and tested for CO oxidation, showing high catalytic performance and stability in reaction. The physicochemical characteristics of the films were examined by Scanning Electron Microscopy (SEM), Temperature-Programmed Reduction (TPR), X-ray Diffraction (XRD), Laser Raman Spectroscopy (LRS), Reflectance Infrared Fourier Transformed Spectroscopy (DRIFTS) and ultrasound tests. The VAP films consisted of thick clustered nanorods containing Cu+ and Cu2+ species in the outer layer of the coating. The CAL films presented uniform growth of nanoneedles in which the outer layers were composed mainly of Cu2+. However, by submitting the CAL sample to the VAP procedure (CAL-VAP), part of CuO was reduced to Cu4O3 species. The developed  microreactors with copper oxide nanostructures directly grown on microchannels with high thermal conductivity represent a low-cost, simple alternative for application in catalytic gas-phase reactions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239768,"idioma_id":5,"titulo":"Las ciudades en el derecho internacional. Especial referencia a la participación en el seno de las Naciones Unidas y la relación entre presencia institucional e impacto normativo","resumen":"La incidencia en las agendas globales es una de las cuestiones más importantes en la acción internacional de las ciudades. Pero debido a que el Derecho Internacional no reconoce a estos entes subjetividad jurídica internacional, el movimiento internacional municipal recurrirá a Naciones Unidas como punto de encuentro y plataforma para la acción política a los fines de establecer el marco normativo internacional que les permita intervenir en aspectos no limitados a la esfera de sus competencias legalmente reconocidas. De esta manera, las ciudades se propondrán dos objetivos en torno a su relación con Naciones Unidas: articulación política y mayor presencia institucional en el seno de la Organización. Al mismo tiempo, ambas cuestiones estarán entrelazadas a los fines de obtener un marco normativo regulatorio respecto a su actividad externa.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239774,"idioma_id":5,"titulo":"Cuestionario de Evaluación de Factores Psicosociales (CEFAP): Estructura y Propiedades Psicométricas","resumen":"A una muestra de 873 trabajadores de organizaciones públicas de Argentina, se ha administrado el Cuestionario de Evaluación de Factores Psicosociales (CEFAP) que incluye once dimensiones, con una serie de ítems con formato tipo Likert organizados de acuerdo con un modelo teórico según el cual éstos cubrirían el espectro de factores psicosociales que contextualizan el trabajo. Todos los factores mostraron una alta consistencia interna, con valores &#945; de Cronbach comprendidos entre .49 (Relación salud-trabajo) y .92 (Apoyo Social y Estima). Además, el cuestionario cuenta con un apartado donde se relevan variables sociolaborales. Los resultados indican que el CEFAP reproduce fielmente la estructura del modelo teórico propuesto ampliando lo presentado por otros instrumentos de evaluación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239779,"idioma_id":5,"titulo":"Expresión de E-cadherina y factor de crecimiento epidérmico en leucoplasias orales.","resumen":"Introducción: Se define a las leucoplasias orales como una placa blanca que no puede desprenderse por raspado y que no puede clasificarse como ninguna otra lesión. Son lesiones con potencial maligno, relacionadas con la presencia de displasia epitelial. Estos cambios preneoplásicos pueden ser evidenciados histológicamente como también a través de técnicas que pongan en evidencia los diferentes cambios a nivel molecular. La E-cadherina es una glicoproteína membranosa que desempeña papeles importantes en el mantenimiento de la adhesión célula-célula, la preservación de la polaridad del tejido epitelial y la integridad estructural. Los factores de crecimiento epidérmico son un conjunto de moléculas de naturaleza proteica, biorreguladores, cuya funcionalidad fundamental radica en el control del ciclo celular. El objetivo del presente trabajo es identifi car y comparar parámetros histológicos y moleculares predictores de riesgo de transformación maligna en leucoplasias orales. Material y métodos: El estudio corresponde a un diseño observacional descriptivo. Se seleccionaron muestras de 26 biopsias de leucoplasias orales, las cuales fueron evaluadas con técnica histológica de rutina y tinción con hematoxilina y eosina, luego sometidas a inmunomarcación con factor de crecimiento epidérmico y E-cadherina, donde se evaluó la intensidad de tinción y cambios en la expresión de cada marcador, así como la localización en los diferentes subtipos celulares. Resultados: De las 26 leucoplasias observadas, 16 mostraron histología con cambios hiperplásicos y 10 con cambios displásicos leves a moderados. La expresión de E-cadherina no mostró alteraciones signifi cativas en leucoplasias sin displasia, sólo hubo pérdida de expresión en aquellas leucoplasias con cambios displásicos de alto grado, en concordancia a los hallazgos histológicos. En leucoplasias con displasia epitelial la expresión del receptor del factor de crecimiento epidérmico fue de leve a moderada a nivel del estrato basal y suprabasal. Para las leucoplasias no displásicas, la tinción mostró un patrón de marcación leve, principalmente en el estrato basal. Conclusión: Con los marcadores estudiados es posible evidenciar cambios moleculares tempranos que se corresponden a los observados en la histología presente, que demuestran cambios biológicos precoces pero su utilidad como marcadores pronósticos es cuestionable. Se requiere un estudio longitudinal con mayor número de muestras para confirmar esta conclusión.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239780,"idioma_id":4,"titulo":"Fisher Vectors for PolSAR Image Classification","resumen":"In this letter we study the application of the Fisher Vector (FV) framework to the problem of pixel-level classification in PolSAR images. This is a challenging problem since the information is encoded in the form of complex-valued covariance matrices. Our approach considers the real part of the pixel-level covariances. We first show that these matrices preserve the symmetric positive definiteness property of their complex counterpart and apply a FV derived from a mixture of real Wishart pdfs. Experimental results on two&nbsp; challenging datasets show the effectiveness of the approach.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239781,"idioma_id":4,"titulo":"Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp","resumen":"Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of Mikania variifolia and Mikania micrantha dichloromethane extracts. Mikanolide and deoxymikanolide were the major compounds in both extracts (2.2% and 0.4% for Mikania variifolia and 21.0% and 6.4% for Mikania micrantha respectively, calculated on extract dry weight). Mikanolide, deoxymikanolide and dihydromikanolide were active against Trypanosoma cruzi epimastigotes (50% inhibitory concentrations of 0.7, 0.08 and 2.5 &#956;g\/mL, for each compound respectively). These sesquiterpene lactones were also active against the bloodstream trypomastigotes (50% inhibitory concentrations for each compound were 2.1, 1.5 and 0.3 &#956;g\/mL, respectively) and against amastigotes (50% inhibitory concentrations for each compound were 4.5, 6.3 and 8.5 &#956;g\/mL, respectively). By contrast, scandenolide was not active on Trypanosoma cruzi. Besides, mikanolide and deoxymikanolide were also active on Leishmania braziliensis promastigotes (50% inhibitory concentrations of 5.1 and 11.5 &#956;g\/mL, respectively). The four sesquiterpene lactones were tested for their cytotoxicity on THP 1 cells. Deoxymikanolide presented the highest selectivity index for trypomastigotes (SI = 54) and amastigotes (SI = 12.5). In an in vivo model of Trypanosoma cruzi infection, deoxymikanolide was able to decrease the parasitemia and the weight loss associated to the acute phase of the parasite infection. More importantly, while 100% of control mice died by day 22 after receiving a lethal T. cruzi infection, 70% of deoxymikanolide-treated mice survived. We also observed that this compound increased TNF-&#945; and IL-12 production by macrophages, which could contribute to control T. cruzi infection.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239782,"idioma_id":4,"titulo":"Decoding the Anticancer Activity of VO-Clioquinol Compound:The Mechanism of Action and Cell Deatrh Pathways in Human Osteosarcoma Cells","resumen":"Vanadium compounds were studied in recent years by considering them as a representative of a new class of non-platinum metal anticancer drugs. However, a few challenges still remain in the discovery of new molecular targets of these new metallodrugs. Studies on cell signaling pathways related to vanadium compounds have scarcely been reported and so far this information is highly critical for identifying novel targets that play a key role in the antitumor actions of vanadium complexes. This research deals with the alterations in the intracellular signaling pathways promoted by an oxovanadium(IV) complex with the clioquinol (5-chloro-7-iodo-8-quinolinol), VO(CQ)2, on a human osteosarcoma cell line (MG-63).Herein are reported, for the first time, the antitumor properties of VO(CQ)2 and the relative abundance of 224 proteins (which are involved in most of the common intracellular pathways) to identify novel targets of the studied complex. Besides, full-length human recombinant AKT1 kinase was produced by using an IVTT system to evaluate the variation of relative tyrosin-phosphorylation levels caused by this compound. The results of the differential protein expression levels reveal several up-regulated proteins such as CASP3, CASP6, CASP7,CASP10, CASP11, Bcl-x, DAPK and down-regulated ones, such as PKB\/AKT, DIABLO, among others. Moreover,cell signaling pathways involved in several altered pathways related to the PKC and AP2 family have been identified in both treatments (2.5 and 10 mM) suggesting the crucial antitumoral role of VO(CQ)2. Finally, it has been demonstrated that this compound (10 mM, 6 h) triggers a decrease of 2-fold in in situ AKT1 expression.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239783,"idioma_id":4,"titulo":"Methane at the NW of Weddell Sea, Antarctica","resumen":"The presence of gaseous hydrocarbons (from methane to n-pentane) in the seabed sediments and the bubbling of methane may suggest the presence of gas accumulations in the substrate of the NW Weddell Sea, Antarctica. The release of methane from the frozen ocean substrate adjacent to Seymour Island would be linked to climate instability during Late Cenozoic, when vast areas ofthe Antarctic continental shelf were flooded during themarine transgression that occurred &#119888;. 18,000 years ago, after the Last Glacial Maximum(LGM). As the ice melted, the sea again occupied the regions which it had abandoned. As the transgression was relatively rapid, the sub-air relief was not destroyed but was submerged and the ground had frozen (permafrost) along with it.Thus, the heat flow from the sea to the marine substrate, now flooded, would have destabilized frozen gas accumulations, which were originally formed into terrestrial permafrost during the LGM, similarly to what would have happened in the Arctic.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239784,"idioma_id":5,"titulo":"EFECTO DE DIFERENTES TIPOS DE COSECHA SOBRE EN LA CALIDAD TECNOLÓGICA DE LA FIBRA DE ALGONDON EN CULTIVOS DE ALTA DENSIDAD.","resumen":"Desde la introducción en la Argentina de los sistemas de producción de algodón en surcos estrechos la superficie de cosecha con plataformas recolectoras de tipo stripper ha aumentado y se han desarrollado variados sistemas. El objetivo del presente trabajo fue evaluar la calidad tecnológica de la fibra en algodones conducidos bajo sistema de surcos estrechos y recolectados bajos diferentes sistemas stripper y su comparación con el sistema picker. A partir del desmote de cada unidad experimental se individualizaron los fardos de fibras producidos y se analizaron por (HVI), obteniéndose un valor de Longitud, Resistencia, Uniformidad, Micronaire, Elongación, Rd y +b para cada fardo la fibra obtenidas con lo que se construyeron tablas de frecuencias según los intervalos de clasificación para cada parámetro de calidad. El análisis de la distribución de frecuencias de los parámetros más significativos que determinan la calidad de la fibra de algodón permitieron detectar mínimos cambios en las distribuciones y estos no modificaron el intervalo de clase con mayor frecuencia, lo que no implicaría cambios en la calidad tecnológica de la fibra cosechada con distintos sistemas de cosecha stripper en relación a la cosecha picker. Los cambios en la distribución fueron mayores cuando el ensayo se realizó en condiciones de secano debido a un menor control de la fructificación del cultivo por lo que pone de relevancia el manejo del cultivo en los sistemas que se cosecharan con sistemas stripper.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239786,"idioma_id":5,"titulo":"RESEÑA de Lastra, Ma. Soledad, Volver del exilio. Historia comparada de las políticas de recepción en las posdictaduras de la Argentina y Uruguay (1983-1989), Buenos Aires, UNLP \/ UNM \/UNGS, 2016, 300 págs.","resumen":"El presente libro es una referencia obligada para todo aquel que se adentre en el campo de estudios sobre los exilios políticos de la última dictadura cívico-militar. Si bien es cierto que se enfoca concretamente sobre las políticas de recepción de exiliados en Argentina y Uruguay durante las posdictaduras, tiene la virtud de presentar un amplio recorrido que nos acerca al pasado reciente de ambos países desde una perspectiva novedosa. Es una obra de síntesis, basadaen la tesis doctoral de María Soledad Lastra, que propone un recorte novedoso basado en la comparación entre los casos argentino y uruguayo.La autora encuentra semejanzas y disonancias entre ambos casos, ubicando en su especificidad los nudos emblemáticos de las historias recientes de estos países. Así, la figura de la desaparición forzada aparece como un hecho clave en el caso argentino, mientras que las continuidades políticas del Uruguay no encuentran su homólogo al otro lado del Río de la Plata.Se trata de un trabajo riguroso, en el cual Lastra recupera un profuso corpus Documental, dentro del cual es de destacar la consulta de acervos documentales que hasta el momento no habían sido trabajados. La originalidad de las fuentes, y el modo de interpelarlas hacen de la obra una interesante hoja de ruta que abre nuevos horizontes a la vez que instala una serie de mojones para pensar los retornos del exilio.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239788,"idioma_id":5,"titulo":"EL PENSAMIENTO BIOMECÁNICO DE MORIZ BENEDIKT: APORTES AL DESARROLLO DE LA BIOMECÁNICA","resumen":"La Biomecánica es una disciplina que tiene un amplio espectro de aplicaciones, siendo fundamental su dominio en gran cantidad y variedad de profesiones. Medicina, terapia física y ocupacional, bioingeniería, kinesiología, biología, física médica, ortoprotésica, antropología, ciencias del deporte, son sólo algunas de las especialidades que requieren conocimientos de Biomecánica. La importancia de su contextualización socio-histórica nos conduce al Dr. Moriz Benedikt, quien habría propuesto y utilizado el término ?Biomecánica? por primera vez en un congreso realizado en Wiesbaden en el año 1887, momento en el que dio inicio a un programa, en tanto acciones ordenadas a lo largo del tiempo, para establecer una nueva ciencia. En el presente trabajo se analizan textos del médico que avalan esta idea, así como el origen de dicho término, su conceptualización espacio-temporal, su vinculación con el neo-vitalismo, las leyes generales, principios y aplicaciones de la Biomecánica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239792,"idioma_id":5,"titulo":"LEY, INDEXACIÓN Y EVALUACIÓN EN TERRITORIO UNIVERSITARIO: UNA APROXIMACIÓN TEÓRICA","resumen":"Este artículo, en líneas generales, trata sobre la ?ideología de la evaluación?. Este término acuñado por Jean Claude Milner alude a los procesos novedosos de evaluación de instituciones, disciplinas  y docentes universitarios acaecidos en las últimas décadas. Ellos han generado una mutación en los conceptos de Ley y Contrato heredados de la modernidad temprana. Co-relacionada a esta mutación histórica; la evaluación de artículos en revistas indexadas y el sistema de indexación de revistas científicas generan nuevos tipos de relación social académica articulados a las nuevas formas de Ley y Contrato ya mencionadas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239795,"idioma_id":5,"titulo":"energía nuclear: Desafíos sociales y ambientales en la provincia de Córdoba-Argentina.","resumen":"Teniendo en cuenta las dificultades crecientes que se van presentando día a día para que las distintas sociedades puedan tener acceso al agua segura para su consumo y para cubrir sus necesidades básicas, y teniendo en cuenta las distintas coyunturas socio-históricas por las cuales las sociedades han atravesado, presentamos en este trabajo una alternativa para reutilizar el agua empleada en las plantas nucleares. En el contexto de la actual situación ambiental y ecológica mundial, sin duda uno de los problemas de mayor trascendencia es el referente al agua, no sólo por las fuertes desigualdades que impone su distribución geográfica, tanto en el tiempo como en el espacio, sino también por las decisiones políticas y económicas que determinan la relación de nuestra sociedad con el agua. En este trabajo, si bien tomamos como ejemplo guía un caso del estado de Florida en los Estados Unidos, nuestro objetivo es presentar alternativas de reutilización de las enormes cantidades de agua empleada en el enfriamiento de los reactores de la provincia de Córdoba, si bien no para consumo humano, sí para otras empleos que tienen que ver con la sustentabilidad socio-ambiental, en especial en una región donde la problemática del agua es una realidad vivida a diario. El ejemplo guía toma a la central nuclear de Turkey Point, que durante 30 años arrojó resultados favorables para las comunidades cercanas a la central nuclear así como para el entorno circundante, sin embargo un punto de quiebre se dio en el año 2013, donde se han abierto nuevas situaciones a partir de esa fecha que han impactado de una forma no esperada sobre el entorno de la central nuclear, situaciones que generan la necesidad de replantearse y reflexionar sobre lo que ha pasado y las decisiones que se han tomado frente a esa problemática. En este sentido, creemos que podemos pensar alternativas de acción en Argentina en relación a la reusabilidad del agua, especialmente en la provincia de Córdoba, donde se encuentran emplazada una de las tres centrales nucleares del país. Los principales resultados tendrán que ver con la posibilidad de reutilización del agua y las implicancias geográfico-espaciales de ella, pero sobre todo, con las decisiones políticas y económicas que involucran tanto a las compañías privadas como a los estados provinciales y federales en un contexto regional y global.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239797,"idioma_id":5,"titulo":"Contratistas rurales y cambios en la estructura agraria pampeana","resumen":"El proceso de concentración económica ocurrido en las últimas décadas en el sector agropecuario argentino, trajo aparejado la desaparición de numerosas explotaciones pequeñas y medianas y la expansión de otras, así como la transformación y el reposicionamiento de algunos sujetos agrarios. En este contexto, se incrementó la relevancia de los contratistas rurales. Bajo esta denominación se incluyen: por un lado, aquellos denominados contratistas de servicios que brindan servicios de maquinaria; por otro, los contratistas de producción que asumiendo todos los riesgos de la actividad  toman a porcentaje campos de terceros por una o más cosechas. Estos dos sujetos sociales pueden ser, a su vez, productores agropecuarios y también, en un mayor nivel de complejidad, reunir las tres figuras en una misma persona. Ambos han tenido un papel significativo en las transformaciones producidas en la estructura agraria de la región pampeana. El objetivo de este artículo es caracterizar a los contratistas rurales, haciendo énfasis en los contratistas de producción (tanteros puros),  que son aquellos  sujetos sociales agrarios que sólo operan bajo contrato accidental, producen con maquinaria propia y, solo a veces, contratan la cosecha. La estrategia metodológica consiste en el reprocesamiento de datos provenientes de los Censos Nacionales Agropecuarios realizados en 1988, 2002 y 2008, para dimensionar la evolución de la demanda de servicios de contratistas rurales. Posteriormente, se seleccionaron las explotaciones agropecuarias  (EAP) relevadas en 2008 cuya forma de tenencia era exclusivamente contrato accidental puro, considerando así que estos productores tienen la maquinaria en propiedad como único capital invertido en el sector, no tienen inversiones en tierra ni en otros bienes de uso y solo algunos contratan servicios de cosecha para su EAP. La sistematización y análisis de la información censal permitió identificar sus principales características así como las estrategias desplegadas por los mismos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239800,"idioma_id":4,"titulo":"A Structural Analysis of topic ontologies","resumen":"DMOZ is the largest human-edited topic ontology available on the Web. This article studies the structural properties of the DMOZ graph. A number of global and local properties of this graph and the subgraphs resulting from isolating edges of different types are examined by means of metrics commonly used in complex network analysis. In particular, we investigate the presence of various features that characterize small-world networks. This analysis is complemented by examining other characteristics of the graphs such as connectivity and centrality measures. The connectivity and centrality patterns are further studied by means of visualizations of the graphs? k-core decomposition and a selection of strongly connected components. Several non-trivial regularities that are also encountered in other artificial and natural complex networks provide a general picture of this large human-edited topic ontology. This analysis is of major pragmatic interest as it allows a better understanding of notions such as navigability among topics, hierarchical structure and topic cohesiveness, which are of great importance in the design of topic ontologies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239801,"idioma_id":4,"titulo":"How to know the fungi: combining field inventories and DNA&#8208;barcoding to document fungal diversity","resumen":"The fungi kingdom is among the most diverse eukaryotic lineages on Earth with estimates of several million extant species (O´Brien et al., 2005; Blackwell, 2011; Taylor et al., 2014). Fungi play critical roles in carbon and nutrient cycling of terrestrial and aquatic ecosystems, and they are important pathogens and mutualists (Read & Perez-Moreno, 2003; Taylor et al., 2012; Grossart et al., 2016). More than 80% of plant species form symbioses with fungi and these symbioses have been crucial to the colonization of terrestrial ecosystems (Field et al., 2015a; Selosse et al., 2015). Despite their impacts on primary ecosystem functions, assessments of fungal biodiversity estimate that only c. 10% of fungal species have been described (Bass & Richards, 2011; Hibbett et al., 2011).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239802,"idioma_id":5,"titulo":"Dos registros de Agaricales (Basidiomycota) exóticos en bosques nativos de la Patagonia argentina","resumen":"Inocybe sindonia (Fr.) P. Karst. y Amanitarubescens Pers. son especies típicamente asociadasa bosques de Pseudotsuga menziesii (Mirb.)Franco y Pinus radiata D. Don respectivamente.Se reporta por primera vez su presencia en Argentinaen bosques de Nothofagus de la Patagoniaandina como resultado de la invasión de especiesforestales introducidas como recurso maderero. I.sindonia fue colectado en bosques de N. dombeyi(Mirb.) Oerst. y A. rubescens en bosques de N.pumilio (Poepp. & Endl.) Krasser en áreas protegidascon invasión evidente de coníferas exóticas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239803,"idioma_id":4,"titulo":"The (re)discovery of ectomycorrhizal symbioses in Neotropical ecosystems sketched in Florian&oacute;polis","resumen":"The VIIIthBrazilian Mycological Congress, held in Florianopolis(Brazil) in October 2016, was organized by the UniversidadeFederal de Santa Catarina and brought together more than 1000scientists of 20 nationalities, which illustrates the dynamism ofSouth American mycology, in many fields. One of the major take-home messages, amongst many research talks and posters, was therising interest in the ectomycorrhizal (EM) symbiosis, which wasaddressedbybothasymposium anda3-day workshop ?Totherootsof trees: growing awareness of ectomycorrhizal symbioses in theNeotropics?. Talks on this symbiosis were given by taxonomists andecologists, and focused on the Neotropics, the tropical realm thatextends from the central plateau of Mexico and which includesSouth America. The inventories of ectomycorrhizal fungi (EMF),observations of EM roots, and metabarcoding studies presentedrevealed a hitherto unsuspected abundance of the EM symbiosis toall participants, including a number of South-American students.This meeting provided great opportunities to share points of viewon the historical reasons behind gaps in knowledge on EMFassociations in neotropical low-elevation areas. The meeting alsohighlighted recent discoveries and forthcoming challenges, basedon three complementary approaches: studies on fruitbodies, EMroots, and the metabarcoding of soil samples.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239804,"idioma_id":4,"titulo":"The Gondwanan connection &ndash; Southern temperate Amanita lineages and the description of the first sequestrate species from the Americas","resumen":"manita is a diverse and cosmopolitan genus of ectomycorrhizal fungi. Although most species fruit aboveground, some sequestrate taxa have been documented from Australia and the Mediterranean region. We describe A. nouhrae sp. nov., a new hypogeous (?truffle-like?) species associated with Nothofagus antarctica in northern Patagonia. This constitutes the first report of a sequestrate Amanita from the Americas. Thick-walled basidiospores ornamented on the interior spore wall (?crassospores?) were observed consistently in A. nouhrae and its sister epigeous taxon A. morenoi. A. morenoi is a rarely collected but apparently common species from northern Patagonia that has sometimes been misidentified as the Australian taxon A. umbrinella. Nuclear 18S and 28S ribosomal DNA and mitochondrial 16S and 26S DNA placed these two species in a southern temperate clade within subgenus Amanita, together with other South American and Australian species. Based on a dated genus-level phylogeny, we estimate that the southern temperate clade may have originated near the Eocene\/Oligocene boundary (ca. 35 Ma ± 10 Ma). This date suggests a broadly distributed ancestor in the Southern Hemisphere, which probably diversified as a result of continental drift, as well as the initiation of the Antarctic glaciation. By comparison, we show that this clade follows an exceptional biogeographic pattern, within a genus otherwise seemingly dominated by Northern Hemisphere dispersal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239805,"idioma_id":4,"titulo":"A systematic overview of Descolea ( Agaricales ) in the Nothofagaceae forests of Patagonia","resumen":"The descolea clade includes species of ectomycorrhizal basidiomycetes in the genera Descolea, Setchelliogaster, Descomyces, and Timgrovea that are known primarily from the Southern Hemisphere. Taxa in this group produce basidiomes that range in morphology from typical epigeous mushrooms (Descolea) and secotioid taxa (Setchelliogaster) to fully gasteroid species (Descomyces and Timgrovea). High intraspecific morphological variation has been reported in several species within this clade, suggesting that careful morphological and molecular studies are needed to refine species concepts. Molecular analyses of fresh Patagonian collections in conjunction with taxonomic studies have confirmed high variability in key morphological features, including overall sporocarp form, spore shape and dimensions, universal veil remnants, and cuticle configuration. Based on our synthesis, we emend the genus Descolea to include sequestrate species. We describe the new sequestrate taxon Descolea inferna sp. nov. from Nothofagaceae forests in Patagonia and we propose Cortinarius squamatus as a synonym of our new combination Descolea brunnea. We also formalize the identity of Descolea pallida as a synonym of Descolea antarctica and provide new specimens of Cortinarius archeuretus, a species that has not been encountered since the original discovery during the expeditions of Roland Thaxter in 1905?1906. Here we re-describe and transfer this species to Descolea as D. archeureta. We also discuss diagnostic features that can be used to delimitate the four known South American taxa in the descolea clade.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239808,"idioma_id":4,"titulo":"Personalization and Competition in Elite Schools in Buenos Aires: School Strategies for the Production and Legitimization of Dominant Groups","resumen":"This article analyses the strategies found in two elite secondary institutions in Buenos Aires designed to legitimise the selection of students aspiring to become members of the elite. The first are personalization strategies where teachers and students work together with the aim of facilitating success in examinations. The second are strategies that promote competition between students, which have the effect of the students being responsible for their success. Field work took place in two schools, where interviews were conducted with the principals, teachers of different subjects and parents. Both schools use examinations as a mechanism for justifying their students? merits, but develop different pedagogies to achieve this. The private school which recruits the children of the economic elite implements strategies to maximise students? results by grouping them according to individual performance and facilitating the development of supportive relationships with teachers. At the public school, individual competition is fostered, where students find themselves in large classes and pupils appear to be an ?anonymous? mass. In this school, where mostly the cultural and intellectual elite send their children, merit is also justified through performance, but it is emphasised that young people have attained high results as a result of their, hard work. Personalization and competition in elite schools in Buenos Aires: school strategies for the production and legitimization of dominant groups (PDF Download Available). Available from: https:\/\/www.researchgate.net\/publication\/313316776_Personalization_and_competition_in_elite_schools_in_Buenos_Aires_school_strategies_for_the_production_and_legitimization_of_dominant_groups [accessed Sep 18, 2017].","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239809,"idioma_id":5,"titulo":"Efectos de la implementación de técnicas anticonceptivas sobre la terminación de vacas descarte","resumen":"Con el objeto de evaluar el aumento de peso vivo (APV) y la terminación en vacas de descarte, mediante la aplicación de métodos anticonceptivos cruentos e incruentos, se desarrolló un diseño en bloques completos al azar, y tres tratamientos: Control (C), Dutto (DT) y Diub (DB), con los bloques definidos por 48 vacas cruza Brangus (B1), y 30 vacas Hereford y Braford (B2). Los parámetros evaluados fueron: APV y Terminación, utilizándose como fuente de variación: Peso Vivo (PV), Condición corporal (CC), Espesor de Grasa Dorsal (GD). Se determinó el PV y CC al inicio y cada 30 días, y GD al inicio y final del ensayo. El ANOVA no arrojó interacción Bloques por Tratamientos, ni tampoco hubo diferencias significativas entre tratamientos para APV Y terminación, sin embargo al analizar por bloques en el B1 se observó un APV mayor en los lotes tratados DB 67 kg, DT 62 kg que en el C 59 kg. En B2 el APV fue mayor para DT 92 kg, mientras que para los demás tratamientos los resultados fueron similares, DB: 80 kg; C: 78 kg. Luego se realizó un análisis de regresión lineal del APV, comparando las pendientes de cada ecuación, con el objetivo de predecir qué pasaría si el período de evaluación del APV fuese más prolongado. El B1 presentó diferencias significativas entre los coeficientes de las pendientes de APV a favor de DT respecto a C, y DT vs DB. En  B2 las diferencias de APV fueron entre C con DT y DB. Es importante desde el  punto de vista del manejo del rodeo en un establecimiento de cría la aplicación de estos métodos anticonceptivos, donde hay presencia de toros y la expectativa de producción de esta categoría animal es vender vacas gordas como descarte, evitando preñeces no deseadas","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239818,"idioma_id":4,"titulo":"Symmetric interpolation, Exchange lemma and Sylvester sums.","resumen":"The theory of symmetric multivariate Lagrange interpolation is a beautiful but rather unknown tool that has many applications. Here we derive from it an Exchange Lemma that allows to explain in a simple and natural way the full&nbsp; description of&nbsp; the&nbsp; double sum expressions introduced by Sylvester in 1853 in terms of subresultants and their B´ezout coefficients.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239820,"idioma_id":4,"titulo":"Grazing increases evapotranspiration without the cost of lowering soil water storages in arid ecosystems","resumen":"Grazing is the predominant land use practice in arid environments; however, there are relatively few studies of grazing effects on ecosystem functioning. We assessed the impact of grazing on soil moisture, evapotranspiration (ET), canopy conductance (Gc), and root water uptake in the Patagonian steppe. Studies were done in 3 sites along a gradient of grazing intensity. High grazing intensity increased the soil water storage by 24% and decreased the amount of water extracted from deep layers compared to the low grazing intensity. Grazing affected ET and its partitioning into transpiration (T) and evaporation. High shrub cover and Gc increased ET and T or ET partitioning in the heavily grazed site. Annual ET increased from 78% to 92% of the annual precipitation from the lowest to the highest grazing intensity, respectively. Total T was 21% higher in the highest intensity site compared to the lowest intensity site. Changes in Gc suggest that grazing modified the canopy architecture, and thus the response of vegetation to environmental factors. At the beginning of the growing season when moisture was high, Gc exhibited the highest value in the heavily grazed site, but a strong regulation of water losses was observed under drier conditions. This study emphasizes the need to assess simultaneously multiple factors for understanding regulatory mechanisms of grazing effects on hydrological processes. From a sustainable management point of view, we suggest that increasing the number of water sources, and thus spreading the sheep in a paddock, can enhance the stocking rate while maintaining soil water storage.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239821,"idioma_id":4,"titulo":"The cost of avoiding freezing in stems: Trade-off between xylem resistance to cavitation and supercooling capacity in woody plants","resumen":"Stems and leaves of Olea europaea L. (olive) avoid freezing damage by substantial supercooling during the winter season. Physiological changes during acclimation to low temperatures were studied in five olive cultivars. Water relations and hydraulic traits, ice nucleation temperature (INT) and temperatures resulting in 50% damage (LT50) were determined. All cultivars showed a gradual decrease in INT and LT50 from the dry and warm summer to the wet and cold winter in Patagonia, Argentina. During acclimation to low temperatures there was an increase in leaf cell wall rigidity and stomatal conductance (gs), as well as a decrease in leaf apoplastic water content, leaf water potential (?), sap flow and stem hydraulic conductivity (ks). More negative ? as a consequence of high gs and detrimental effects of low temperatures on root activity resulted in a substantial loss of ks due to embolism formation. Seasonal stem INT decrease from summer to winter was directly related to the xylem resistance to cavitation, determined by the loss of ks across cultivars. Thus the loss of freezable water in xylem vessels by embolisms increased stem supercooling capacity and delayed ice propagation from stems to the leaves. For the first time, a trade-off between xylem resistance to cavitation and stem and leaf supercooling capacity was observed in plants that avoid extracellular freezing by permanent supercooling. The substantial loss of hydraulic function in olive cultivar stems by embolism formation with their high repair costs are compensated by avoiding plant damage at very low subzero temperatures.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239822,"idioma_id":5,"titulo":"Nuevo registro del Arasarí fajado (Pteroglossus castanotis) en la provincia de Corrientes, Argentina","resumen":"El Arasarí Fajado (Pteroglossus castanotis) (Aves: Ramphastidae) contaba con un solo registro en la provincia de Corrientes, en Puerto Luján (departamento Ituzaingó), localidad situada sobre la costa del río Paraná en el límite con laprovincia de Misiones. En esta comunicación presentamos nuevos registros documentados de esta especie en el Establecimiento Las Marías, departamento Santo Tomé. Estas observaciones, las primeras en más de 20 años, permiten confirmar su presencia en el nordeste de Corrientes","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239827,"idioma_id":5,"titulo":"El ojo parpadeante del poema: derivas críticas de la imagen objetiva en la poesía argentina contemporánea","resumen":"En el presente artículo, propongo un recorrido crítico por poemas de Fabián Casas, Martín Gambarotta, Daniel García Helder y Martín Prieto para puntualizar y analizar instancias donde las imágenes objetivas son desfondadas y producen el advenimiento de otro tipo de régimen de la mirada ?el de la imagen sustraída?&nbsp; que se articula como crítica de lo visible, a partir de una temporalidad que pone en evidencia las distancias y desfasajes entre percepción y escritura.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239832,"idioma_id":5,"titulo":"Reseña: MESTMAN, Mariano (coord.), Las rupturas del 68 en el cine de América Latina (Editorial Akal, 2016)","resumen":"Reseña crítica del libro Las rupturas del 68 en el cine de América Latina, coordinado por Mariano Mestman. Editorial Akal, 2016.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239833,"idioma_id":5,"titulo":"Atom Egoyan&rsquo;s Remember. Vices and virtues of the memory systems Remember de atom egoyan. Vicis i virtuts dels sistemes de mem&ograve;ria Remember de Atom Egoyan vicios y virtudes de los sistemas de memoria","resumen":"The extensive work of the Canadian-Armenian filmmaker Atom Egoyan has been characterized to addressing, among other topics, the ways in which we relate to the past and how our memory is mediated by various types of technology in the construction and conservation of our memories. In Remember (2015), his last feature film t to day, he returns to this topic aiming to represent the operation and the failures of memory. In the present essay, we will not carry out an aesthetic analysis but rather focus on the form and modes in which the memory is represented in this film. For this purpose, we propose to study it from an inquiry into the memory systems to account for its multiple layers and characteristics, just as we will account for some ?sins? that will allow us to analyze not only its distortions but also its ways of working. Finally we will give space to think the place of the imagination in our relations with the past.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239838,"idioma_id":10,"titulo":"Flora das cangas da Serra dos Carajás, Pará, Brasil: Rubiaceae","resumen":"Este estudo compreende as espécies de Rubiaceae que ocorrem sobre canga na Serra dos Carajás, estado do Pará, Brasil, incluindo chaves de identificação, descrições detalhadas,ilustrações e comentários morfológicos das espécies, bem como a sinonimização de dois nomes (Chomelia parvifolia e Tocoyena bullata). No total, foram registradas 48 espécies em 24 gêneros, entre as quais distinguem-se, em ambientes abertos, táxons da tribo Spermacoceae, com um gênero monotípico endêmico da região, Carajasia cangae, bem como diversas espécies de distribuição restrita (ex. Borreria carajasensis, B. elaiosulcata, B. heteranthera e Mitracarpus carajasensis). Nos ambientes florestais encontrados sobre canga, o gênero com maior número de espécies é Psychotria (9 espécies).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239840,"idioma_id":4,"titulo":"UV-B radiation on lemons enhances antifungal activity of flavedo extracts against Penicillium digitatum","resumen":"UV-B radiation (UVBR) treatment, previously standardized in our laboratory, contributes to prevent green mold caused by Penicillium digitatum on postharvest lemons. Here, antifungal activity of flavedo extracts from irradiated and non-irradiated lemons was assayed against P. digitatum; also, compoundsthat could be responsible for this action were searched. The flavedo extracts from UV-B exposed lemons (UVBLE) exhibited a higher antimicrobial activity than extracts from control lemons (CLE). Conidia treated with UVBLE showed a time dependent inhibition of germination and oxygen consumption, a markedly increase in ROS and TBARS production and in membrane permeability. By chemical analysis of lemon extracts, two fractions (A and B) that responded to the irradiation were detected, showing a decrease in Fraction A and an increase in Fraction B. Fraction B showed higher antioxidant and antifungal activities in comparison to Fraction A. Both fractions were complex samples enriched in flavonoids. Thespecific composition of each fraction could explain the difference in the biological activities, and also the higher efficiency of UVBLE to inhibit in vitro the pathogen compared to CLE. Based on our results, UV-B radiation treatment can intensify natural defenses of flavedo lemon by eliciting phenolic compounds synthesis, among other processes","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239841,"idioma_id":4,"titulo":"Anatomical and Physiological Responses of Four Quinoa Cultivars to Salinity at Seedling Stage","resumen":"Objectives: Salinity is one of the most important environmental stress factors that limits both seed germination and seedling develop. Seedling stage is the most susceptible stage of plants to salt stress. The aim of this work is to study the effect of salt stress on anatomical and physiological features of cotyledons and roots of the seedlings of four quinoa cultivars (Witulla, Wariponcho, Pasankalla and CICA). Methods\/ Statistical Analysis: Seed germination and seedling growth was carried out under 0 and 200 mM NaCl during 10 days. Root length and diameter, and root proton extrusion were measured. Soluble sugars and proline concentrations were determined in both cotyledons and roots. Anatomical attributes of cotyledons (adaxial and abaxial stomatal area and density, palisade and spongy cell layers, palisade cell density) and roots (stele diameter and surface, metaxylem vessel diameter) were also analyzed. Findings: Salt stress caused physiological and anatomical changes in cotyledons and roots. Sucrose, glucose and fructose concentrations were more affected in cotyledons than in roots of salt-treated seedlings. Proline accumulation was more affected in roots. Saline stress affected differentially the anatomical attributes of quinoa cultivars. Application\/Improvements: Quinoa seedlingswhen subjected to salt stress are able to develop a set of anatomical, physiological and biochemical adaptive mechanisms which seem to occur at different combinations among quinoa cultivars, but giving similar abilities to cope with the excess of salt and survive under extreme conditions","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239842,"idioma_id":5,"titulo":"Cómo representar en español la voz del protopope Avvákum","resumen":"Traducir al castellano en tanto texto literario una obra compleja como la ?Vida del protopope Avvákum? implica tomar en cuenta los rasgos fundamentales de la lengua en la que está escrita, o mejor, de la lengua en la que hoy la leemos. A una escritura uniformada por un skaz popular, Avvákum entremezcla citas bíblicas en eslavo eclesiástico así como también imita esta lengua en algunos pasajes donde lo siente pertinente. A ese deslizamiento entre dos registros marcados y contrastantes que es constante en toda la obra, nos parece oportuno agregar otro aspecto fundamental: el hecho de que estamos ante un texto antiguo, y la impresión de que de ello parece derivar gran parte de su potencia poética. Ese extrañamiento en la superficie textual advertiría a la vez sobre la distancia entre el universo de sentido que le da sustancia y nuestra cosmovisión actual. ¿Debe una traducción asumir todos esos contrastes? ¿Con qué recursos? ¿Es lícito comprender los rasgos arcaicos de una obra como parte de su estilo y dar cuenta de ellos en nuestra versión?","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239843,"idioma_id":4,"titulo":"Experiences in Development and Application of Simplified Technologies for Rehabilitation and Gait Analysis","resumen":"We focus in developing and applying simplified low-cost technologies that allow an approach to rehabilitation process and make it accessible to the most number of subjects. We present two cases: the mechanical equipment for gait stimulation, and the computer system for gait analysis. In both cases we have developed technologies that are being applied with patiens with terapeutical results in concordance with literature. Statistical validation is being performed. These experiences provide access to rehabilitation technologies to a significant amount of patients, professionals and institutions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239849,"idioma_id":5,"titulo":"OZONO UNA ALTERNATIVA EFICIENTE Y SEGURA PARA EL CONTROL DE PLAGAS EN GRANOS ALMACENADOS","resumen":"OZONO UNA ALTERNATIVA EFICIENTE Y SEGURA PARA EL CONTROL DE PLAGAS EN GRANOS ALMACENADOS","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239851,"idioma_id":5,"titulo":"La Comunidad Judeo-argentina y el primer peronismo","resumen":"El propósito de este trabajo es fundamentar las relaciones entre la identidad judeoargentinay el movimiento político liderado por Juan Domingo Perón desde un marcohistórico ontológico. Esto permite romper con los estereotipos que se construyeron entorno a este episodio de la historia de la ideología populista argentina y latinoamericana","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239857,"idioma_id":4,"titulo":"TP73 DNA methylation and Upregulation of deltaNp73 are associated with an adverse prognosis in breast cancer","resumen":"Aims Accumulated evidences support the fact that aberrantmethylation of TP73 gene andincreased levels of deltaNp73 in primary tumors have been shown to correlate withpoor prognosis. However, little is known regarding the transcriptional andfunctional regulation of the TP73gene in breast cancer. The aim of the present study was to determine theexpression of deltaNp73 isoform, its relation to DNA methylation of TP73 and their clinical prognosticsignificance in breast cancer patients. Methods The TP73 gene methylation was studied inTCGA datasets and in 70 invasive ductal breast carcinomas (IDC). The expression of p73 isoforms was evaluated byimmunohistochemistry and western blot and it was correlated with clinicopathological variables and clinical outcome. Results&nbsp;We observed that the methylation of diverse CpG islands of TP73differed significantly between molecular subtypes. Inverse correlation wasfound between p73 protein expression and the methylation status of TP73 gene. The expression of exon 3?of p73 (only expressed in &#916;Np73), wassignificantly higher in patients with wild-type p53. Immunohistochemistryanalysis revealed that all p73 isoforms were localized in both the nuclear andcitoplasmatic compartment. We confirmed towards a positive association betweenexpression of deltaNp73 and high histological grade. Conclusions Our findings suggest that high expression of deltaNp73 could be could be used to determine the aggressiveness of IDCs and could beincorporated in the pathologist´s report. &nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239861,"idioma_id":4,"titulo":"Design of a Decoupling Strategy and Parameter Calculation for Six-Phase PM Machines with General Angular Displacement","resumen":"A novel decoupling model with parameter calculation for a six-phase permanent magnet machine is proposed in this paper. The model considers the machine as two independent three-phase stator windings that are spatially shifted by a generic angle &#945;. The proposed transformation considers the zero sequence and allows to eliminate the coupling between phases. The parameters, which define the dynamicbehavior of the model, are calculated with simulations performed using the finite element method. The decoupled model and the parameters are analyzed for two configurations of a traditional six-phase machines. Simulation results were validated by experimental results with a simple procedure.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239862,"idioma_id":4,"titulo":"Preliminary design for simultaneous saccharification and fermentation stages for ethanol production from sugar cane bagasse","resumen":"The interest of ethanol production from agro-industry residues as raw material has deserved great attention since these feedstocks may constitute an alternative to fossil fuels as well as represent beneficial effects both from economic and environmental point of view. The sugar cane bagasse (SCB) represents an available and cheap opportunity of raw material. The use of lignocellulosic biomass as a feedstock needs a pretreatment stage to breakdown lignocellulosic complex into lignin, cellulose and hemicelluloses, then the hydrolysis stage converts cellulose into fermentable glucose, and finally, in order to increase the glucose yield, simultaneous saccharification and fermentation (SSF) process is carried out. In this work a preliminary design for these stages is proposed. A mixed integer linear programming model is formulated in order to obtain the optimal number of parallel units in each stage and their sizes (plant configuration and capacity). The production planning along the time horizon of one year is determined, given by the number of batches to be processed and its size. Different production scenarios are analyzed, for which the investment cost is minimized, and economic profitability indicators are calculated.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239863,"idioma_id":4,"titulo":"Medication discrepancies and potentially inadequate prescriptions in elderly adults with polypharmacy in ambulatory care","resumen":"Objectives: The objective of this study is to describe the frequency and type of medication discrepancies (MD) through medication reconciliation and to describe the frequency of potentially inadequate prescription (PIP) medications using screening tool of older persons? prescriptions criteria. Design: Cross&#8209;sectional comparison of electronic medical record (EMR) medication lists and patient?s self&#8209;report of their comprehensive medication histories obtained through telephone interviews. Inclusion criteria: Elderly individuals (>65 years old) with more than ten medications recorded in their EMR, who had not been hospitalized in the past year and were not under domiciliary care, affiliated to a private community hospital. Outcome Measures: The primary outcomes were the proportion of patients with MD and PIP. Secondary outcomes were the proportion of types of discrepancies and PIP. We analyzed possible associations between these variables and other demographic and clinical variables. Results: Out of 214 randomly selected individuals, 150 accepted to participate (70%). The mean number of medications referred to be consumed by patients was 9.1 (95% confidence interval [CI] =8.6?9.6), and the mean number of prescribed medications in their EMR was 13.9 (95% CI = 13.3?14.5). Ninety&#8209;nine percent had at least one discrepancy (total 1252 discrepancies); 46% consumed at least one prescription not documented in their EMR and 93% did not consume at least one of the prescriptions documented in their EMR. In 77% of the patients, a PIP was detected (total 186), 87% of them were at least within one of the following categories: Prolonged used of benzodiazepines or proton pump inhibitors and the use of aspirin for the primary prevention of cardiovascular disease. Conclusions: There was a high prevalence of MD and PIP within the community of elderly adults affiliated to a Private University Hospital. Future interventions should be aimed at reducing the number of PIP to prevent adverse drug events and improve EMR accuracy by lowering medications discrepancies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239864,"idioma_id":4,"titulo":"Crystallographic Texture Evolution of a Zinc Sheet Subjected to Different Strain Paths","resumen":"The use of zinc sheets has largely increased in the last years, fundamentally because of new tendencies in architecture and, at the same time, due to its excellent properties, as corrosion resistance under aggressive climatic conditions, malleability, recyclability, and surface finishing aspect. In the present work, the X-ray diffraction technique is used to characterize the crystallographic texture evolution of a strongly anisotropic Zn20 zinc sheet (Zn-Cu-Ti) subjected to uniaxial tension, plane strain, and equibiaxial tension, for specimens cut at 0, 45, and 90 deg with respect to the rolling direction. The crystallographic texture evolution is evaluated by means of pole figures, orientation distribution function, and Kearns factors. For all tested strain paths, deformation produces a decrease in the intensity of the crystallographic textures, due to a dispersion of the orientations of the different axes around the initial maxima.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239865,"idioma_id":4,"titulo":"Is it Possible to Use Rolling Methods to Improve Textures on Fe-Mn-Si Shape Memory Alloys?&thinsp;","resumen":"No uniform rolling deformation produces shear strains that give rise to textural and microstructural heterogeneities in processed metals and alloys. In this work, the authors investigate Fe?30Mn?4Si shape memory alloy sheets rolled in different conditions at 600 C, in order to determine the process giving rise to the best structure and the strongest {100}&lt;110&gt; shear texture. This crystallographic orientation is the most favorable for the g &#8594; e martensitic transformation, which provides the shape memory effect in these alloys. In the current conditions, the authors find that unidirectional rolling produces a shear texture in sheet?s surface layers. The authors compare the texture and microstructure from this process to those obtained from reverse rolling and single-roller drive rolling.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239866,"idioma_id":4,"titulo":"Development and validation of various phenotyping algorithms for Diabetes Mellitus using data from Electronic Health Records.","resumen":"Background and Objective: Recent progression towards precision medicine has encouraged the use of electronic health records (EHRs) as a source for large amounts of data, which is required for studying the effect of treatments or risk factors in more specific subpopulations. Phenotyping algorithms allow to automatically classify patients according to their particular electronic phenotype thus facilitating the setup of retrospective cohorts. Our objective is to compare the performance of different classification strategies (only using standardized problems, rule-based algorithms, statistical learning algorithms (six learners) and stacked generalization (five versions)), for the categorization of patients according to their diabetic status (diabetics, not diabetics and inconclusive; Diabetes of any type) using information extracted from EHRs.Methods: Patient information was extracted from the EHR at Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. For the derivation and validation datasets, two probabilistic samples of patients from different years (2005: n=1663; 2015: n=800) were extracted. The only inclusion criterion was age (&#8805;40 & <80 years). Four researchers manually reviewed all records and classified patients according to their diabetic status (diabetic: diabetes registered as a health problem or fulfilling the ADA criteria; non-diabetic: not fulfilling the ADA criteria and having at least one fasting glycemia below 126 mg\/dL; inconclusive: no data regarding their diabetic status or only one abnormal value). The best performing algorithms within each strategy were tested on the validation set.Results: The standardized codes algorithm achieved a Kappa coefficient value of 0.59 (95% CI 0.49, 0.59) in the validation set. The Boolean logic algorithm reached 0.82 (95% CI 0.76, 0.88). A slightly higher value was achieved by the Feedforward Neural Network (0.9, 95% CI 0.85, 0.94). The best performing learner was the stacked generalization meta-learner that reached a Kappa coefficient value of 0.95 (95% CI 0.91, 0.98).Conclusions: The stacked generalization strategy and the feedforward neural network showed the best classification metrics in the validation set. The implementation of these algorithms enables the exploitation of the data of thousands of patients accurately.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239868,"idioma_id":4,"titulo":"Resistance of phages lytic to pathogenic Escherichia coli to sanitisers used by the food industry and in home settings","resumen":"Phages are potentially useful as antimicrobial agents in food-processing environments, provided they can remain active upon extended storage and in the presence of sanitisers. Survival of six phages lytic againstenteropathogenic (EPEC) and shiga-toxigenic (STEC) Escherichia coli strains was assessed upon storage at 4 °C, 20 °C and 70 °C in phosphate-buffered-saline (PBS) and Tris-magnesium-gelatine buffer (TMG) for up to 1 year. The phages were also exposed to ethanol, sodium hypochlorite, peracetic acid, quaternary ammonium chloride (biocide A), hydrogen peroxide\/peracetic acid\/peroctanoic acid (biocide B), p-toluensulfonchloroamide (biocide D) and alkaline chloride foam (biocide C). Plaque-forming units remained unchanged when the phages were stored at 4 °C in both buffers tested, but decreased by 3.5 and 5.7 log10 PFU when stored in PBS at 20 and 70 °C, respectively. Moreover, TMG seems to be the most protective suspension medium with decreasing temperature because a 1log10 PFU reduction was observed at 20 and 70 °C. Incubation in 100% ethanol for 24 h reduced plaque counts only by 2.5 log10 PFU. In 10 ppm of sodium hypochlorite and in biocide B (0.13%), the counts decreased by ~5 and ~6 log10 PFU after15 min. Finally, biocide A and D reduced counts by 4 and 2?4 log10 PFU after 30 min and 8 h of incubation, respectively. Phages were completely inactivated only by peracetic acid and biocides C and E. Therefore, the phages evaluated might be potentially applied together with classical sanitisers such as ethanol andindustrial biocides A, B and D, in disinfection programs against pathogenic STEC and EPEC strains.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239869,"idioma_id":5,"titulo":"Los videojuegos serios: puentes de creatividad y expansión educativa?","resumen":"En la actualidad las tecnologías de la información y la comunicación (TIC) atraviesan contextos culturales, sociales y políticos que a su vez las reconfiguran y les dan significatividad. Enmarcar las tecnologías en rasgos de época nos permite comprender que son producciones culturales estrechamente integradas en los contextos socio-históricos de referencia. Entre los rasgos de época, reconocemos como valiosos ciertos objetos culturales que por su potencia y proyección generan modos novedosos de construcción del conocimiento. Los videojuegos serios invitan como inmersiones a experimentar y a comprender como objeto de la cultura otros modos de aprender en la contemporaneidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239871,"idioma_id":5,"titulo":"Automatic detection of Web Incompatibilities using Digital Image Processing.","resumen":"La compatibilidad de un sitio web es la propiedad que lo permite serapreciado idénticamente en todos los navegadores. La creciente necesidad deque los sitios web puedan ser compatibles, ha llevado a que las empresasrealicen análisis de múltiples factores en materia de visibilidad durante lasetapas de desarrollo. Pero la continua evolución de los navegadores hace queeste análisis no sea suficiente para evitar incompatibilidades entre ellos,cobrando relevancia las pruebas de compatibilidad web. Por otro lado, hoy endía las empresas buscan alcanzar el enfoque de desarrollo de software continuo,donde el objetivo es mantener la producción de software en ciclos cortos detiempo, acelerando los procesos de pruebas. Uno de los desafíos que existeactualmente, es la aceleración de las pruebas sobre la interfaz de usuario, entreellas, las de compatibilidad. En este trabajo se presenta una técnica paraautomatizar la detección de defectos de incompatibilidad, mediante el uso delprocesamiento digital de imágenes. Los resultados de su implementaciónindican que se adapta a los requerimientos de los procesos de desarrollocontinuo, aumentando el rendimiento y la velocidad de las pruebas ydisminuyendo la cantidad de falsos positivos que normalmente aparecen en estetipo de pruebas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239872,"idioma_id":4,"titulo":"Tubulin is retained throughout the human hematopoietic\/erythroid cell differentiation process and plays a structural role in sedimentable fraction of mature erythrocytes","resumen":"We investigated the properties of tubulin present in the sedimentable fraction (?Sed-tub?) of human erythrocytes, and tracked the location and organization of tubulin in various types of cells during the process of hematopoietic\/erythroid differentiation. Sed-tub was sensitive to taxol\/nocodazole (drugs that modify microtubule assembly\/disassembly), but was organized as part of a protein network rather than in typical microtubule form. This network had a non-uniform ?connected-ring? structure, with tubulin localized in the connection areas and associated with other proteins. When tubulin was eliminated from Sed-tub fraction, this connected-ring structure disappeared. Spectrin, a major protein component in Sed-tub fraction, formed a complex with tubulin. During hematopoietic differentiation, tubulin shifts from typical microtubule structure (in pro-erythroblasts) to a disorganized structure (in later stages), and is retained in reticulocytes following enucleation. Thus, tubulin is not completely lost when erythrocytes mature; it continues to play a structural role in the Sed-tub fraction.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239873,"idioma_id":4,"titulo":"Reactive oxygen species generated in chloroplasts contribute to tobacco leaf infection by the necrotrophic fungus Botrytis cinerea","resumen":"Reactive  oxygen  species  (ROS)  play  fundamental  roles  in  plant  responses  to pathogen infection, including modulation of cell death processes and defense-related gene  expression.  Cell  death  triggered  as  part  of  the  hypersensitive  response enhances  resistance  to  biotrophic  pathogens,  but  favors  virulence  of  necrotrophs. Even  though  the  involvement  of  ROS  in  the  orchestration  of  defense responses  is well established, the relative contribution of specific subcellular ROS sources to plant resistance  against  microorganisms  with  different  pathogenesis  strategies  is  not completely known. The aim of this work was to  investigate the role of chloroplastic ROS in plant defense against a typical necrotrophic fungus, Botrytis cinerea. For this purpose,  we  used  transgenic  tobacco  lines  expressing  a  plastid-targeted cyanobacterial flavodoxin (pfld lines), which accumulate lower chloroplastic ROS in response to different stresses. Tissue damage and fungal growth were significantly reduced  in  infected  leaves  of  pfld  plants,  as  compared  to  infected  wild-type  (WT) counterparts.  ROS  build-up  triggered  by  Botrytis  infection  and  associated  to chloroplasts was significantly decreased (70-80%) in pfld leaves relative to the wild type. Phytoalexin accumulation and expression of pathogenesis-related genes were induced  to  a  lower  degree  in  pfld  plants  than  in  WT  siblings.  The  impact  of  fungal infection on photosynthetic activity was also lower in pfld leaves. The results indicate that  chloroplast-generated  ROS  play  a  major  role  in  lesion  development  during Botrytis infection. This work demonstrates that the modulation of chloroplastic ROS levels by expression of a heterologous antioxidant protein can provide a significant degree of protection against a canonical necrotrophic fungus. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239875,"idioma_id":4,"titulo":"Dated phylogenetic studies of the southernmost American buthids (Scorpiones; Buthidae)","resumen":"A dated molecular phylogeny of the southernmost American species of the family Buthidae, based on two nuclear and two mitochondrial genes, is presented. Based on this study, analyzed species of the subgenus Tityus (Archaeotityus) are neither sister to the remaining species of the genus Tityus, nor are they closely related to the New World microbuthids with decreasing neobothriotaxy. Analyzed species of the subgenus Tityus do not form a monophyletic group. Based on ancestral area estimation analyses, known geoclimatic events of the region and comparisons to the diversification processes of other epigean groups from the area, a generalized hypothesis about the patterns of historical colonization processes of the family Buthidae in southern South America is presented. Furthermore, for the first time, a Paleogene-African ingression route for the colonization of America by the family Buthidae is proposed as a plausible hypothesis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239876,"idioma_id":4,"titulo":"Mauryius n.gen. (Scorpiones: Bothriuridae), a new neotropical scorpion genus","resumen":"Mauryius, n.gen., a new bothriurid scorpion genus from the Argentinean Precordillera, is described, and its phylogenetic position is discussed based on a phylogenetic analysis of morphological data. Mauryius, n.gen. is the first scorpion genus endemic to the Argentinean Precordillera. It is most closely related to Pachakutej Ochoa, 2004 from the inter-Andean valleys of Peru and to Rumikiru Ojanguren-Affilastro, Mattoni, Ochoa & Prendini, 2012 from the Atacama Desert in Chile. Mauryius cuyanus, n.sp., the only known species of the genus, is described. Biogeographical implications of Mauryius relationships are discussed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239879,"idioma_id":4,"titulo":"Cyclic deformation mechanisms and microcracks behavior in high-strength bainitic steel","resumen":"The purpose of this investigation is to analyze the mechanisms of cyclic deformation and the initiation and propagation of microcracks during low cycle fatigue in the bainitic steel 16CrMnV7-7. The slip systems and their associated Schmid Factor are analyzed in the bainitic ferrite laths and correlated with the short crack path using scanning electron microscopy observations (SEM) in combination with electron backscattered diffraction (EBSD) measurements. Moreover, the developed dislocation structure was analyzed and correlated with the formation and propagation of microcracks. The principal results show that microcracks initiate in lath boundaries and along slip systems with the highest Schmid Factor and low Taylor Factor. Besides, it was observed after experimental evidence that the parameters controlling crack propagation are associated with the crystallographic misorientation between bainite blocks and with the tilt\/twist misorientation angle between slip planes of adjacent bainitic ferrite laths.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239882,"idioma_id":4,"titulo":"Cyclic deformation mechanisms and microcracks behavior in high-strength bainitic steel","resumen":"The purpose of this investigation is to analyze the mechanisms of cyclic deformation and the initiation and propagation of microcracks during low cycle fatigue in the bainitic steel 16CrMnV7-7. The slip systems and their associated Schmid Factor are analyzed in the bainitic ferrite laths and correlated with the short crack path using scanning electron microscopy observations (SEM) in combination with electron backscattered diffraction (EBSD) measurements. Moreover, the developed dislocation structure was analyzed and correlated with the formation and propagation of microcracks. The principal results show that microcracks initiate in lath boundaries and along slip systems with the highest Schmid Factor and low Taylor Factor. Besides, it was observed after experimental evidence that the parameters controlling crack propagation are associated with the crystallographic misorientation between bainite blocks and with the tilt\/twist misorientation angle between slip planes of adjacent bainitic ferrite laths.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239886,"idioma_id":4,"titulo":"Explaining coexistence of nitrogen fixing and non-fixing rhizobia in legume-rhizobia mutualism using mathematical modeling","resumen":"In the mutualism established between legumes and soil bacteria known as rhizobia, bacteria from soil infect plants roots and reproduce inside root nodules where they fix atmospheric N2 for plant nutrition, receiving carbohydrates in exchange. Host-plant sanctions against non N2 fixing, cheating bacterial symbionts have been proposed to act in the legume- Rhizobium symbiosis, to preserve the mutualistic relationship. Sanctions include decreased rhizobial survival in nodules occupied by cheating rhizobia. Previously, a simple population model experimentally based showed that the coexistence of fixing and cheating rhizobia strains commonly found in field conditions is possible, and that the inclusion of sanctions leads to the extinction of cheating strains in soil. Here, we extend the previous model to include other factors that could complicate the sanction scenario, like horizontal transmission of symbiotic plasmids,turning non-nodulating strains into nodulating rhizobia, and competition between fixing and cheating strains for nodulation. In agreement with previous results, we show that plant populations persist even in the presence of cheating rhizobia without incorporating any sanction against the cheater populations in the model, under the realistic assumption that plants can at least get some amount of fixed N2 from the effectively mutualistic rhizobia occupying some nodules. Inclusion of plant sanctions leads to the unrealistic extinction of cheater strains in soil. Our results agree with increasing experimental evidence and theoretical work showing that mutualisms can persist in presence of cheating partners.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239893,"idioma_id":5,"titulo":"Raymond Aron un intelectual de 'todos los tiempos': Su aporte a las Relaciones Internacionales","resumen":"El trabajo reflexiona sobre algunos de los conceptos y categorías de análisis por él propuestos que permiten no sólo considerarlo un ?adelantando? o un teórico ?de vanguardia? para su época sino un intelectual vigente aún hoy ya que con su impronta sociológico-histórica apostó a la comprensión de la ?complejidad? de la sociedad internacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239894,"idioma_id":4,"titulo":"Indirect ELISA (iELISA) for routine detection of antibodies against Mouse Minute Virus (MVM) in mice colonies","resumen":"In this study we developed an indirect ELISA to detect antibodies against Minute Virus of Mice (MVM) using an antigen produced from BHK-21 cells infected with a prototype strain of the virus. The optimal antigen concentration and serum dilutions were established. In order to analyze variability in the laboratory, reproducibility and repeatability within and between plates were determined. Then, a panel of 460 sera from conventional facilities and previously classified as positive or negative by the indirect fluorescent antibody assay was analyzed. The cutoff value was determined by a receiver operating characteristic (ROC) curve. The results of the indirect ELISA were compared with those of the indirect fluorescent antibody assay. The ELISA assay showed 100% sensitivity and 99% specificity. ELISA is a useful tool to be developed in standard virology laboratories and can be used for screening animals faster than the traditional indirect fluorescent antibody assay.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239897,"idioma_id":5,"titulo":"La heurística del AUTÓMATON aristotélico en fenómenos de recurrencia cíclica del  sector inmobiliario y financiero","resumen":"Este artículo tiene como objetivo principal analizar las posibilidades hermenéuticas del concepto AUTÓMATON en la explicación de ciertos tipos de fenómenos de recurrencia cíclica en la economía del sector inmobiliario y financiero. Por otra parte, se realza el valor heurístico de este concepto a través de su diálogo con la perspectiva recurrente de la historia de Louis Auguste Blanqui.  La hipótesis principal señala que los ciclos de crecimiento inmobiliario de la construcción y posterior crisis financiera se dan en un marco de falta de finalidad o de causa final; según la perspectiva aristotélica. La actualización de la perspectiva aristotélica o el giro interpretativo que proponemos es que esta falta de finalidad debe verse como una imposibilidad de trascender o de superar la reiteración constante de esos ciclos. Esta imposibilidad de trascendencia se debe a la pérdida progresiva, por parte de la sociedad de consumo, de la noción legal de límite. En función del diálogo entre el Libro II de la Física de Aristóteles y el texto de Louis Auguste Blanqui La eternidad a través de los astros planteamos que lo que se reitera en vano no es una excrecencia paralela al esquema de cuatro causas aristotélico sino que todo el tiempo histórico humano es AUTÓMATON. Es decir, el texto de Blanqui nos da la posibilidad de transformar el Autómaton aristotélico en un concepto de valor heurístico más amplio que trabaje la recurrencia cíclica inmanente o sin capacidad de superarse. Para las dos hipótesis desarrolladas ha sido clave la perspectiva teórica aportada por Gilles Deleuze y Félix Guattari en sus estudios sobre el capitalismo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239898,"idioma_id":4,"titulo":"Pedigree-based estimation of covariance between dominance deviations and additive genetic effects in closed rabbit lines considering inbreeding and using a computationally simpler equivalent model","resumen":"Inbreeding generates covariances between additive and dominance effects (breeding values and dominance deviations). In this work, we developed and applied models for estimation of dominance and additive genetic variances and their covariance, a model that we call ?full dominance,? from pedigree and phenotypic data. Estimates with this model such as presented here are very scarce both in livestock and in wild genetics. First, we estimated pedigree-based condensed probabilities of identity using recursion. Second, we developed an equivalent linear model in which variance components can be estimated using closed-form algorithms such as REML or Gibbs sampling and existing software. Third, we present a new method to refer the estimated variance components to meaningful parameters in a particular population, i.e., final partially inbred generations as opposed to outbred base populations. We applied these developments to three closed rabbit lines (A, V and H) selected for number of weaned at the Polytechnic University of Valencia. Pedigree and phenotypes are complete and span 43, 39 and 14 generations, respectively. Estimates of broad-sense heritability are 0.07, 0.07 and 0.05 at the base versus 0.07, 0.07 and 0.09 in the final generations. Narrow-sense heritability estimates are 0.06, 0.06 and 0.02 at the base versus 0.04, 0.04 and 0.01 at the final generations. There is also a reduction in the genotypic variance due to the negative additive?dominance correlation. Thus, the contribution of dominance variation is fairly large and increases with inbreeding and (over)compensates for the loss in additive variation. In addition, estimates of the additive?dominance correlation are 0.37, 0.31 and 0.00, in agreement with the few published estimates and theoretical considerations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239899,"idioma_id":5,"titulo":"Primer registro de Nopachtus coagmentatus (Xenarthra, Glyptodontidae) para la Provincia de Catamarca, Argentina. Revisi&oacute;n del g&eacute;nero Nopachtus","resumen":"Nopachtus coagmentatus fue reconocido por Ameghino en 1888. El holotipo procede de la Formación Brochero (Montehermosense - Chapadmalalense [Plioceno temprano - Plioceno tardío]), de las cercanías de Villa Cura Brochero (Córdoba). Se reporta el primer hallazgo de esta especie para la Provincia de Catamarca. Se describe el material hallado, se detalla su procedencia y se presenta el perfil estratigráfico detallado correspondiente. El material mencionado, procedente de la Formación Salicas aflorante en el paraje de Suri Yaco, consiste en 14 osteodermos de la coraza dorsal que se atribuyen a N. coagmentatus, 12 completos y 2 fragmentados correspondientes a la región media y póstero-dorsal de la coraza dorsal. Estos osteodermos presentan una figura central rodeada por dos hileras de figuritas periféricas y figuritas que corresponderían a una tercera hilera, siempre incompleta. La primera hilera tiene entre 10 y 12 figuritas y la segunda entre 19 y 22; las figuritas son pentagonales o, mayoritariamente, hexagonales. A su vez, se revisa todo el material hasta ahora conocido para este género, que incluye dos especies. Para N. coagmentatus solamente había dos registros fehacientes, hasta esta comunicación, y varios dudosos, en tanto que para N. cabrerai Zamorano, Scillato-Yané, González Ruiz & Zurita solo se dio a conocer el holotipo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239902,"idioma_id":5,"titulo":"Effect of the cellular and humoral immune response in infertile couples and its  relationship with infections.","resumen":"OBJECTIVE: The purpose of this study was to determine the prevalence of differentmicroorganisms isolated from the urogenital tract of infertile men and assesswhether there are differences in semen parameters according to the presence orabsence of genital infections.METHODS: 280 semen samples from infertile men were studied retrospectively. Semenparameters were analyzed according to the World Health Organization criteria (WHO2010). Microbiological analysis was performed using the modified method of Stameyand Meares proposed by Santoianni et al.RESULTS: Microbiological studies showed absence of microorganisms or presence of usual colonizing flora in 67.86% of the samples (GROUP 1) and presence of atleast one pathogen or potential pathogen in 32.14% (GROUP 2). No significantdifferences in ejaculate volume (p=0.353), pH value (p=0.801), motility (p>0.30),citric acid concentration (p=0.383) and viscosity (p=0.948) were observed betweenthe two groups. The relative sperm count was significantly lower in infectedpatients than in those without pathogens (p=0.05). Teratozoospermia index (TZI)was evaluated. Samples of infected patients showed TZI values higher thanpatients without microorganisms or normal genital tract flora (p<0.0001).CONCLUSIONS: A third of the studied population had genital infections. Based onour results, sperm culture may be considered in the early stages of the study of the infertile patient. Early diagnosis of an infectious disease could be usefulfor a suitable treatment for couples with reproductive failure.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239903,"idioma_id":4,"titulo":"EVALUATION OF THE IMPLEMENTATION OF A NEW COURSE SYSTEM","resumen":"Introduction: University assesses knowledge through written and oral tes. Our course has implemented an evaluation system that allows us to obtain information and assessment of proposed leaming outcomes effectively and reliably. In 2011 we applied changes, introducing the term competition(strategic mobilization of the knowledge elements, skills and attitudes) as resources available and necessary to respond to a given situation.Objective: to evaluate course system change and train students in the generation of criteria, development of attitudes and skills, in the resolutions of situations that may appeart in profesional life.Methods: the new system desing consists of theoretical chronological clases concatenated with theoretical practical clases, lab practice and 3 tests including knowledge with a passing grade of 7. This method was used since 2011. In previous periods, the course was passed with final exams after regularization. Results: since 2011, 187 students were enrolled, where 83,96 % was promoted with 9 to 7, 10,70 % regularized and 5,35 % falled, previous periods until the proposed change (2001 ti 2010), 26,09 % out of 874 exams passed with 10 to 7, 41,76 % were absent. But with the current system, 90,60 % of the students passed the exams and only 10% were absent.Conclusion: This system allowed us to see in the student knowledge, skills and attitudes that apply to daily situations in their professionally future. Academic performance was optomized, and absenteeism decreased.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239904,"idioma_id":5,"titulo":"ARAN-NOR","resumen":"El proyecto está destinado a desarrollar productos farmacéuticos con extractos de arándanos, y promover consumo de los mismos por las excelentes propiedades antioxidantes. Nuestro grupo de trabajo viene estudiando frutos cultivados en el NOA comprobando el contenido de componentes fisiológicamente activos. Las investigaciones y desarrollo farmacéutico tienden a convertir el concepto de un nuevo medicamento en realidad, desarrollando fórmulas estables que tengan ventajas comparativas en el mercado global. Para ello se realizan caracterizaciones fisicoquímicas y biológicas de los nuevos productos, desarrollando métodos analíticos exactos y precisos para la cuantificación de los principios activos y excipientes, evaluando cada formulación expuesta a diferentes condiciones de temperatura y humedad (estudios de estabilidad), los que ofrecen un alto estándar de calidad para los productos. En nuestra provincia la producción de frutos finos está creciendo en forma sostenida y el desarrollo de productos farmacéuticos con arándanos podría fortalecer de la cadena de comercialización.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239905,"idioma_id":5,"titulo":"QUIN-TUC","resumen":"El proyecto está destinado a crear conciencia sobre la importancia de la quinoa, revalorizándola para emplearla en la producción de productos farmacéuticos y\/o alimentos.Nuestro grupo de trabajo viene estudiando semillas andinas comprobando el contenido de componentes fisiológicamente activos. El desarrollo de QUIN-TUC se efectúa a partir de extractos de quinoa, optimizando el aprovechamiento de componentes antioxidantes, fibra dietética que pueden contribuir en la prevención enfermedades. Teniendo en cuenta estas propiedades químicas y biológicas es factible el desarrollo de un nutracéutico de alta calidad y bajo costo para la prevención y tratamiento de algunas patologías.En nuestro país la producción de granos andinos como la quinoa está creciendo en forma sostenida, siendo necesario agregar valor agregado esta materia prima a nivel regional, impulsando el desarrollo sustentable del cultivo, con fortalecimiento de la cadena de comercialización.Palabras claves: quinoa, nutracéuticos, desarrollo de producto","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239907,"idioma_id":5,"titulo":"Re-conocimiento de las religiones afrobrasileñas en Rosario: racconto de un proceso de segregación social","resumen":"En este artículo ensayo algunas hipótesis sobre el lugar de marginalidad al que están confinadas las religiones afrobrasileñas en Rosario. Propongo que esta situación es resultado de un entramado de diferentes matrices performativas de diferenciación social que se fueron tejiendo a lo largo de la historia. Éste está vinculado a un paradigma excluyente implementado a nivel nacional como modo de organización socio-cultural, que tuvo en esta ciudad sus ribetes particulares. Para ello, expondré brevemente la trayectoria de vida de una Mae de santo con la cual trabajé durante casi 10 años, focalizándome en ciertas adscripciones sociales: religiosas, raciales y sexo-genéricas. Luego retomaré a varios investigadores ?historiadores y antropólogos? para situar el contexto rosarino, tomando estas variables de adscripción como aquellos ejes a partir de los cuales se fue organizando una ciudad bajo parámetros de diferenciación y segregación social altamente performativos (productivos de un determinado orden y una determinada forma de ser y habitar ese entramado urbano). Finalmente, señalaré cómo este entramado local se configura como el espacio de socialización en el cual los devotos plasman su agencia y producen su práctica religiosa, debiendo sobrellevar esta trama altamente excluyente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239908,"idioma_id":5,"titulo":"Cultivo de mandioca en invernadero: efectos sobre el rendimiento y la calidad de raíces tuberosas.","resumen":"Dada la fuerte interacción entre la temperatura ambiente y elrendimiento de raíces tuberosas (RT) de mandioca, en regionessubtropicales el cultivo bajo invernadero puede ser una tecnologíade producción a considerar si se quiere incrementar el rendimientoy adelantar la cosecha. El objetivo de este trabajo fueevaluar cuantitativa y cualitativamente la producción de RT demandioca bajo invernadero en un suelo arenoso de Corrientes,Argentina. Para ello se estudiaron variaciones temporales decomponentes del rendimiento; índice de cosecha (IC); y contenidosde almidón, proteínas, fibra bruta y minerales de RT de trescultivares (Blanca de Santa Catarina, Ramada Paso y Rocha).El experimento se condujo mediante un diseño en bloques completos al azar, con tres repeticiones. El peso fresco de RT porplanta mostró una interacción genotipo-tiempo significativa. Elnúmero de RT se mantuvo en el tiempo en cada cultivar, aunquese presentaron diferencias entre genotipos. A los 193 díasdespués de plantación, los IC superaron valores de 0,5. Loscontenidos de almidón no difirieron entre genotipos, siendo másprecoces Blanca de Santa Catarina y Rocha. Se encontraroncorrelaciones negativas entre tiempo y contenidos de proteínay fibra bruta, y una asociación muy alta entre éstos. No hubodiferencias estadísticas en contenidos de minerales en el tiempo.En conclusión, es factible producir mandioca bajo invernaderoalcanzando rendimientos elevados y cosechas tempranas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239913,"idioma_id":5,"titulo":"La educación moral en la universidad","resumen":"HJK","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239918,"idioma_id":5,"titulo":"Importancia del Diagnostico Radiografico como preventivo de las anomalias en la erupcion dentaria","resumen":"La erupción de los dientes permanentes puede verse afectada por trastornos ocasionados por distintos factores etiológicos. El problema típico se crea por el desplazamiento de un diente de su ruta de erupción normal, o como consecuencia de un traumatismo que da lugar a una anquilosis.Existen factores generales o locales que afectan la salidade los dientes,retrasándola o impidiéndola. la erupción está vinculada al reloj genético como tantos otros procesos del desarrollo infantil; hay niños de crecimiento lento o precoz en los que la erupción es tardía o se adelanta, siguiendo un esquema que se repite en miembros de la misma familia, es por lo que en las radiografías panorámicas,podemos valorar varios factores que influyen de manera considerable en la erupción dentaria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239919,"idioma_id":5,"titulo":"FOLP-UNLP: Creación de Nuevo Laboratorio de Biología Molecular y Biotecnología.","resumen":"Se ha creado un nuevo espacio en la Facultad de odontología de la UNLP, destinado a la investigación e innovación tecnológica que va a permitir trabajar sobre células madres y biotecnología para generar una odontología regenerativa  de vanguardia. El Nuevo Laboratorio de Biología Molecular y Biotecnología Odontológica  surge con el fin de crear nuevos proyectos y trabajar las líneas de investigación institucional creando un ámbito propicio para que los investigadores puedan desarrollar sus experiencias dentro de la Facultad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239920,"idioma_id":4,"titulo":"Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation","resumen":"We have previously found that UV irradiation promotes RNA polymerase II (RNAPII) hyperphosphorylation and subsequent changes in alternative splicing (AS). We show now that UV-induced DNA damage is not only necessary but sufficient to trigger the AS response and that photolyase-mediated removal of the most abundant class of pyrimidine dimers (PDs) abrogates the global response to UV. We demonstrate that, in keratinocytes, RNAPII is the target, but not a sensor, of the signaling cascade initiated by PDs. The UV effect is enhanced by inhibition of gap-filling DNA synthesis, the last step in the nucleotide excision repair pathway (NER), and reduced by the absence of XPE, the main NER sensor of PDs. The mechanism involves activation of the protein kinase ATR that mediates the UV-induced RNAPII hyperphosphorylation. Our results define the sequence UV-PDs-NER-ATR-RNAPII-AS as a pathway linking DNA damage repair to the control of both RNAPII phosphorylation and AS regulation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239921,"idioma_id":4,"titulo":"Review of the Eriococcidae  (Hemiptera: Coccomorpha) infesting Fabaceae in Argentina, with descriptions of  three new species of Acanthococcus Signoret","resumen":"Three new species of Eriococcidae from Argentina, namely Acanthococcus haywardi Juárez & González sp. nov., A.punctatae Juárez & González sp. nov. and A. riojensis Juárez & González sp. nov., are described and illustrated, bringingthe total number of eriococcid species now known from Argentina to 12, of which six belong to Acanthococcus Signoretand six to Hempelicoccus Kozár. They are found on 11 species of Fabaceae (subfamilies Mimosoideae and Caesalpinioidae),are widely distributed and are all restricted to the Neotropical region and the South American Transitional Zone. Akey to the 12 Eriococcidae species now known on Fabaceae in Argentina is included.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239922,"idioma_id":4,"titulo":"Alpha Hemoglobinophaties in Rosario, Argentina","resumen":"Hemoglobinopathies are the most common recessive diseases worldwide. Whilethe molecular basis of b-thalassemia in Rosario has been addressed, that of &#945;-thalassemiaand &#945; structural alterations, has not. In this study 105 individuals from different families referred to our center were investigated for alpha hemoglobinopathies because of low MCV (&lt;85 fL), low MCH (&lt;27dg), normal HbA2 (&#8804;3.5%) and transferrin saturation of &gt;15%. Six of them with a clinical phenotype of thalassemia intermedia were diagnosed as Hb H disease (five cases) and Hb H like (one case). It also included one patient with sickle cell trait,confirmed by hematological and molecular studies. We were able to identify alpha globingenes mutations in 92 individuals (87.6%): 88 patients with alpha thalassemia, 3 patients with structural alterations and one with both. In total, 13 individuals (12.4%) had no identified &#945;-globin mutation. This study is the first to deal with the molecular basis of -hemoglobinophaties in Rosario.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239926,"idioma_id":5,"titulo":"Hernia Obturatriz Complicada. Conducta Diagnóstica y Terapéutica","resumen":"La hernia obturatriz HO es una entidad poco frecuente aceptándose una incidencia del 0.05 al 1.4% de todas las hernias. Descripta por de Ronsil en 1724, predomina en mujeres anscianas desnutridas. Generalmente se las diagnostica por su complicación que es la obstrucción intestinal cuyo diagnóstico y tratamiento precoz ayuda a disminuir la morbi mortalidad. En el presente trabajo se describen tres pacientes con HO complicada diagnosticada por TC abdomino pélvica y se analiza la bibliografía","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239927,"idioma_id":4,"titulo":"Single particle tracking of internalized metallic nanoparticles reveals heterogeneous directed motion after clathrin dependent endocytosis in mouse chromaffin cells","resumen":"Most accepted single particle tracking methods are able to obtain high-resolution trajectories forrelatively short periods of time. In this work we apply a straightforward combination of single-particletracking microscopy and metallic nanoparticles internalization on mouse chromaffin cells to unveil theintracellular trafficking mechanism of metallic-nanoparticle-loaded vesicles (MNP-V) complexes afterclathrin dependent endocytosis. We found that directed transport is the major route of MNP-Vsintracellular trafficking after stimulation (92.6% of the trajectories measured). We then studied theMNP-V speed at each point along the trajectory, and found that the application of a seconddepolarization stimulus during the tracking provokes an increase in the percentage of low-speedtrajectory points in parallel with a decrease in the number of high-speed trajectory points. This resultsuggests that stimulation may facilitate the compartmentalization of internalized MNPs in a morerestricted location such as was already demonstrated in neuronal and neuroendocrine cells (Bronfmanet al 2003). Although further experiments will be required to address the mechanisms underlying thistransport dynamics, our studies provide quantitative evidence of the heterogeneous behavior of vesiclesmobility after endocytosis in chromaffin cells highlighting the potential of MNPs as alternative labelsin optical microscopy to provide new insights into the vesicles dynamics in a wide variety of cellularenvironments","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239928,"idioma_id":4,"titulo":"Cadmium effects on some energy metabolism variables in Cnesterodon decemmaculatus adults","resumen":"This work is focused on the responses of someenergy metabolism variables in Cnesterodon decemmaculatusadults exposed to cadmium under controlled laboratoryconditions. This species has been used as bioindicatorfor evaluating the effects of different chemicals on diversebiological processes and is frequently used as test organismin ecotoxicity studies that include cadmium as referencetoxicant. Animals were exposed for 12 days to the followingconcentrations: 0, 0.45, and 0.8 mg Cd\/L. Food intake,fecal production, specific assimilation, condition factor,mortality percentage, oxygen consumption, oxygen extractionefficiency, specific metabolic rate, ammonia excretion,and ammonia quotient were measured. The overall balancewas expressed as scope for growth (SFG). Cadmiumexposedgroups showed a significant decrease in foodassimilation and condition factor at the end of the exposure.There was an increase in specific metabolic rate and adecrease in SFG in the group exposed to 0.8 mg Cd\/L. Thecondition factor and the SFG appeared as sensitive biomarkersof health status and growth of the animals,respectively. Cadmium-exposed fish reduced food intake,which was reflected in a decreased assimilation with concomitant decline in the external energy supply fromfeeding. Our results highlight the importance of consideringthe metabolic status of the test organisms when analyzingthe responses of the biomarkers usually used as effectparameters in ecotoxicological evaluations under experimentalconditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239929,"idioma_id":5,"titulo":"Acción estatal para la prevención del trabajo infantil en Corrientes: Programa Crecer sin Trabajo Infantil","resumen":"El Trabajo Infantil es conceptualizado por el  Plan Nacional para la Erradicación del Trabajo Infantil de la CONAETI como: toda actividad económica y\/o estrategia de supervivencia, remunerada o no, realizada por niñas y niños, por debajo de la edad mínima de admisión al empleo o trabajo, o que no han finalizado la escolaridad obligatoria o que no han cumplido los 18 años si se trata de trabajo peligroso.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239934,"idioma_id":4,"titulo":"Human Sialidase Neu3 is S-Acylated and Behaves Like an Integral Membrane Protein","resumen":"Membrane-bound sialidase Neu3 is involved in the catabolism of glycoconjugates, and plays crucial roles in numerous biological processes. Since the mechanism of its association with membranes is still not completely understood, the aim of this work was to provide further information regarding this aspect. Human Neu3 was found to be associated with the plasma membrane and endomembranes, and it was not released from the lipid bilayer under conditions that typically release peripheral membrane proteins. By different experimental approaches, we demonstrated that its C-terminus is exposed to the cytosol while another portion of the protein is exposed to the extracellular space, suggesting that Neu3 possesses the features of a transmembrane protein. However, in silico analysis and homology modeling predicted that the sialidase does not contain any &#945;-helical transmembrane segment and shares the same &#946;-propeller fold typical of viral and bacterial sialidases. Additionally, we found that Neu3 is S-acylated. Since this post-translational modification is restricted to the cytosolic side of membranes, this finding strongly supports the idea that Neu3 may contain a cytosolic-exposed domain. Although it remains to be determined exactly how this sialidase crosses the lipid bilayer, this study provides new insights about membrane association and topology of Neu3.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239936,"idioma_id":4,"titulo":"Water pollution monitoring of the Lujan River (Argentina): chemical analyses and hepatic biomarkers in Lithobates catesbeianus tadpoles","resumen":"The toxicological water quality of theLujan River (Argentina) was monitored during one year seasonal samplings. Watersamples were collected at two points and their toxicological profiles werecompared: S1 (reference site), located downstream of a major city and S2,located further downstream, beyond a joint urban sewage and industrialdischarge point. A number of abiotic parameters were determined and three waterquality indices (WQIs) calculated on the samples. Laboratory toxicity bioassayswere conducted exposing Lithobates catesbeianus larvae to samples; a third group of animals were exposed to tap water (controls). Hepatic biomarkers weredetermined: catalase (CAT), glutathione-S-transferase (GST) and superoxidedismutase (SOD) activities, lipid peroxidation (LPO) and GSH content; CF and HSI were calculated. The scores of the WQIs corresponded to a high pollution condition at both sampling points. ANOVA showed significant differences between sampling sites and controls mainly in CAT activity, GSH content and GST in autumn.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239937,"idioma_id":4,"titulo":"Cadmium effects on some energy metabolism variables in Cnesterodon decemmaculatus adults","resumen":"This work is focused on the responses of some energy metabolism variables in Cnesterodon decemmaculatus adults exposed to cadmium under controlled laboratory conditions. This species has been used as bioindicator for evaluating the effects of different chemicals on diverse biological processes and is frequently used as test organism in ecotoxicity studies that include cadmium as reference toxicant. Animals were exposed for 12 days to the following concentrations: 0, 0.45, and 0.8&#8201;mg&#8201;Cd\/L. Food intake, fecal production, specific assimilation, condition factor, mortality percentage, oxygen consumption, oxygen extraction efficiency, specific metabolic rate, ammonia excretion, and ammonia quotient were measured. The overall balance was expressed as scope for growth (SFG). Cadmium-exposed groups showed a significant decrease in food assimilation and condition factor at the end of the exposure. There was an increase in specific metabolic rate and a decrease in SFG in the group exposed to 0.8&#8201;mg&#8201;Cd\/L. The condition factor and the SFG appeared as sensitive biomarkers of health status and growth of the animals, respectively. Cadmium-exposed fish reduced food intake, which was reflected in a decreased assimilation with concomitant decline in the external energy supply from feeding. Our results highlight the importance of considering the metabolic status of the test organisms when analyzing the responses of the biomarkers usually used as effect parameters in ecotoxicological evaluations under experimental conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239939,"idioma_id":4,"titulo":"Water pollution monitoring of the Lujan River (Argentina): chemical analyses and hepatic biomarkers in Lithobates catesbeianus tadpoles","resumen":"The toxicological water quality of the Lujan River (Argentina) wasmonitored during one year seasonal samplings. Water samples were collectedat two points and their toxicological profiles were compared: S1 (referencesite), located downstream of a major city and S2, located further downstream,beyond a joint urban sewage and industrial discharge point. A number ofabiotic parameters were determined and three water quality indices (WQIs)calculated on the samples. Laboratory toxicity bioassays were conductedexposing Lithobates catesbeianus larvae to samples; a third group of animalswere exposed to tap water (controls). Hepatic biomarkers were determined:catalase (CAT), glutathione-S-transferase (GST) and superoxide dismutase(SOD) activities, lipid peroxidation (LPO) and GSH content; CF and HSI werecalculated. The scores of the WQIs corresponded to a high pollution conditionat both sampling points. ANOVA showed significant differences betweensampling sites and controls mainly in CAT activity, GSH content and GST inautumn.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239940,"idioma_id":5,"titulo":"Formación en geometría analítica para futuros profesores. Un estudio de caso basado en el MKT","resumen":"Este artículo pretende caracterizar la formación que se ofrece a futuros profesores de matemáticas en busca de configurar su conocimiento matemático para enseñar (MKT) geometría analítica elemental. Se analiza el aporte disciplinar de la asignatura Geometría I, de una carrera de formación de profesores de matemáticas en Argentina. Se procura identificar en detalle los dominios del MKT mediante las acciones realizadas por el profesor y los contenidos vistos en las primeras clases de geometría analítica. La investigación, que se aborda mediante un estudio de caso, tiene un enfoque eminentemente cualitativo y un alcance principalmente descriptivo. Los resultadosrevelan que todos los dominios del MKT se activaron en las clases observadas. La diversidady especificidad de tales activaciones puede servir como guía para orientar metodológicamente estudios que se basen en el modelo teórico de referencia, en la línea de formación de profesores en geometría analítica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239941,"idioma_id":4,"titulo":"Campylobacter isolates from different stages of the poultry meat supply chain in Argentina.","resumen":"The objective of this study was to investigate a clonal relationship among thermotolerant Campylobacter isolates from different stages of the poultry meat supply chain in Argentina. A total of 128 thermotolerant Campylobacter (89 C. jejuni and 39 C. coli) isolates from six poultry meat chains were examined. These isolates were from: a) hens from breeder flocks, b) chickens on the farm (at ages 1wk and 5wk), c) chicken carcasses in the slaughterhouse, and d) chicken carcasses in the retail market. Chickens sampled along each food chain were from the same batch. Campylobacter isolates were analyzed using pulsed-field gel electrophoresis (PFGE) to compare different profiles according to the source. Clustering of C. jejuni isolates resulted in 17 profiles, with four predominant genotypes and many small profiles with just a few isolates or unique patterns, showing a very high degree of heterogeneity among the C. jejuni isolates. Some clusters included isolates from different stages within the same chain, which would indicate a spread of strains along the same poultry meat chain. Moreover, twenty-two strains of C. coli  clustered in seven groups and the remaining 17 isolates exhibited unique profiles. Evidence for transmission of thermotolerant Campylobacter through the food chain and cross contamination in the slaughterhouses were obtained. This collective evidence should be considered as the scientific basis to implement risk management measures to protect the public health.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239942,"idioma_id":4,"titulo":"Quantification of FITC-labelled probiotic Lactobacillus salivarius DSPV 001P during gastrointestinal transit in broilers","resumen":"The knowledge related to the fate of probiotics in the complex environment of the intestinal microbiota in broilers is just beginning to be elucidated; however, it is not yet well understood. A good method to investigate the mechanisms by which probiotics mediate their effects is to mark probiotic bacteria and trace them. The aim of this research was to develop a new method to estimate in vivo fluorescein isothiocyanate (FITC)-labelled Lactobacillus salivarius DSPV 001P counts during passage through the gastrointestinal tract (GIT) of broilers. Forty-five, 1 d old Cobb broilers were used in this trial. Programmed necropsies were performed 30 min, 6 h, and 12 h after the administration of the probiotic bacterium, and samples of liver, crop, duodenum, caecum, and bursa of fabricius were collected. To determine the spatial and temporal transit of L. salivarius DSPV 001P in broilers, the number of bacteria as well as its respective fluorescent signal produced by FITC were measured. In order to observe the relationship between the variables, a logistic regression analysis was applied. The amount of fluorescence could be used as an indicator of fluorescent probiotic bacteria in the crop and duodenum 30 min after probiotic bacterium supplementation. In addition, the fluorescent signal could be used to estimate bacterial counts in caecum 6 and 12 h after L. salivarius DSPV 001P administration. To the best of our knowledge, this research is the first in vivo trial to employ the bacterial FITC-labelling technique in order to enumerate probiotic bacteria during gastrointestinal transit in broilers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239943,"idioma_id":5,"titulo":"Efecto de la fertilización nitrogenada y la edad del rebrote sobre el valor nutritivo de Brachiaria brizantha cv. 'Marandú'","resumen":",","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239953,"idioma_id":5,"titulo":"Notas sobre el currículum en escuelas de elite en Buenos Aires: aportes acerca de la diferenciación de las instituciones","resumen":"Este artículo explora el contenido de la experiencia escolar en las escuelas de elite de la Argentina. Se analiza el currículum desplegado por las instituciones como propuesta cultural que las escuelas ponen a disposición de las familias. Los resultados se basan en entrevistas en profundidad realizadas en 5 escuelas de la Ciudad y la Provincia de Buenos Aires así como en el análisis de documentos y de páginas web institucionales. Las propuestas curriculares de las escuelas generan experiencias de aprendizajes y de relación que familiariza a los estudiantes con las posiciones, las estéticas y los ?valores? diferenciadoresdel sector\/grupo social al que pertenecen.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239954,"idioma_id":5,"titulo":"Consecuencias de la implementación de técnicas anticonceptivas sobre la terminación de vacas descarte","resumen":"Con el objeto de evaluar el aumento de peso vivo (APV) y la terminación envacas de descarte, mediante la aplicación de métodos anticonceptivos cruentos e incruentos, se desarrolló un diseño en bloques completos al azar y tres tratamientos: control (C), Dutto (DT) y Diub (DB), con los bloques definidos por 48 vacas cruza Brangus (B1), y 30 vacas Hereford yBraford (B2). Los parámetros evaluados fueron: APV y terminación, utilizándose como fuente de variación: peso vivo (PV), condición corporal (CC) y espesor de grasa dorsal (GD). PV y CC se determinaron al inicio y cada 30 días, y GD al inicio y final del ensayo. El ANOVA no arrojó interacción bloques por tratamientos, ni tampoco hubo diferencias significativas entretratamientos para APV y terminación, sin embargo al analizar por bloques, en B1 se observó un APV mayor en los lotes tratados (DB 67 kg y DT 62 kg) que en el lote C (59 kg). En B2 el APV fue mayor para DT (92 kg), mientras que para los demás tratamientos los resultados fueron similares (DB 80 kg, C 78 kg). Luego se realizó un análisis de regresión lineal del APV,comparando las pendientes de cada ecuación con el objetivo de predecir qué pasaría si el período de evaluación del APV fuese más prolongado. El B1 presentó diferencias significativas entre los coeficientes de las pendientes de APV a favor de DT respecto a C, y DT vs DB. En B2 las diferencias de APV fueron entre C con DT y DB. Es importante desde el punto de vista del manejo del rodeo en un establecimiento de cría, la aplicación de estos métodos anticonceptivos donde haya presencia de toros y la expectativa de producción de esta categoría animal sea vender vacas gordas como descarte, evitando preñeces no deseadas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239955,"idioma_id":4,"titulo":"A Educação Privada na Argentina e no Brasil","resumen":"Exploring the concept of segmentation, this article demonstrates how the expansion of the Argentinian and Brazilian school systems has been associated to processes of school differentiation that have contributed to the production and reproduction of educational inequalities. Based on the analysis of historical statistics on literacy and enrollment as well as of documents that register the transformations of the school system since the end of the 1800s, the article shows, first, that in both school systems, segmentation processes were and are based on the separation between public and private education rather than on differentiation of public schools curriculum. It shows also that while this type of segmentation is quite recent in Argentina, it is an old feature of the Brazilian school system. Finally, the article documents a progressive convergence between the two systems, as the private schools still offer a reserved space for the schooling of the Brazilian privileged groups and has increased this role in Argentina in the last decades.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239957,"idioma_id":5,"titulo":"'No todo lo que brilla es oro: límites, inconsistencias y retos del gobierno abierto en América Latina'","resumen":"El gobierno abierto parece haber llegado para quedarse. Creada en septiembre de 2011, la Alianza para el Gobierno Abierto ya reúne a la fecha a 70 países, 15 de los cuales pertenecen a América Latina. De acuerdo con los principios de transparencia, participación y colaboración, los gobiernos de estos países presentan planes de acción, organizan cumbres y participan de múltiples encuentros junto con representantes de organismos internacionales y ONG.El objetivo de este artículo consiste en re&#64258;exionar sobre los límites, las inconsistencias y los retos del gobierno abierto a partir de nuestra experiencia en el mundo académico, principalmente a través de la investigación aplicada, la formación y la consultoría en América Latina con eje en la Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239960,"idioma_id":4,"titulo":"XRD and EBSD analysis of anisotropic microstructure development in cold rolled F138 stainless steel","resumen":"The microstructural characteristics of deformation-processed materials highly influence their mechanical properties. For a complete characterization of a microstructure both local and global information must be gathered, which requires the combination of different analysis techniques. X-ray and Electron Backscatter Diffraction were used in the present paper to characterize the deformation induced in a cold rolled F138 austenitic stainless steel sample. The results obtained using laboratory and synchrotron X-ray sources were compared and combined with EBSD quantitative results, allowing the global and local characterization and orientation dependence of the deformation microstructure. A particular behavior was observed in the XRD data corresponding to the planes with &#8741; ND, likely due to a smaller amount of defects accumulated in the crystals with that particular orientation. EBSD was used to separate the scans data into partitions and to calculate misorientation variables and parameters, showing that this behavior can be attributed to a combination of larger grain sizes, lower local boundary misorientations and dislocation densities for crystals having &#8741; ND. Several conclusions, of general validity for the evaluation of microstructure anisotropy, can be extracted from the results.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239961,"idioma_id":4,"titulo":"Strain path dependence of anisotropic microstructure evolution on low Stacking Fault Energy F138 steel","resumen":"Severe Plastic Deformation (SPD) techniques are widely used nowadays because of the mechanical properties improvements caused by grain refinement and development of dislocation arrays. Diffraction techniques can be used to assess the changes registered in the microstructure through these methods. Two sets of samples of F138 austenitic stainless steel were analyzed in this paper: one set was deformed by ECAE up to two pressings at room temperature, and the other set was cold rolled to 70% reduction and annealed at 600, 700, 800 and 900 °C for 1 h. The microstructural changes were determined using X-Ray diffraction and EBSD, combining both, global and local information and characterizing domain sizes, dislocation and stacking fault densities and misorientation degree and distribution caused by the different thermomechanical processing. It was observed that, despite cold rolling and 2 ECAE passes rendered rather similar von Mises deformations, the microstructure through each deformation method was different: 2 ECAE passes seem to be more effective for grain refinement and generation of equiaxed domains than cold rolling. The more significant twin activation observed in the former sample, because of continuous strain path change, may explain the difference, although dislocation densities and mechanical properties did not differ substantially for both deformation methods.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239962,"idioma_id":4,"titulo":"Electron backscatter diffraction study of orientation gradients at the grain boundaries of a polycrystalline steel sheet deformed along different loading paths","resumen":"In a polycrystal, the heterogeneity of plastic deformation in a particular grain is greatly enhanced by adjacent grains that constrain the grain?s local behavior, often imposing orientation gradients. This work aims to characterize and quantify the local orientation gradients near grain boundaries (GBs). Electron backscatter diffraction (EBSD) measurements were made on a 0.67 mm thick aluminium-killed drawing quality (AKDQ) steel sheet subjected to differentloading paths that are typical of forming operations. A statistical analysis shows that a considerable fraction of the analyzed GB profiles can be described by an orientation profile with a constant slope near the GB. In order to quantify this behavior, as well as the degree of localization, two new parameters, based on the local orientation gradient assessed by EBSD, are proposed: BET (boundary effective thickness) and GAS (gradient average severity). These parameters should be considered together, the BET as an effective thickness of the GB zone where the orientation gradient takes place and the GAS as a measure of the magnitude or severity of the orientation gradient. Additionally, the GAS parameter shows a strong correlation with the accumulated macroscopic strain for the investigated deformation levels and loading paths, while the BET profile clearly reveals the influence of the GB on the misorientation profiles. Tension and biaxial stretching results lead to a BET value between 1.5 and 2 mm. Finally, it is shown that the local misorientation in the GB zone, on both sides of the GB line, is disperse and it does not correlate simply with misorientation or even the slip-transfer geometry across the GB. Moreover, the observed average local misorientation dispersions in GB zones are different for each loading condition.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239963,"idioma_id":4,"titulo":"Severe Plastic Deformation by Equal Channel Angular Pressing and Rolling: The Influence of the Deformation Path on Strain Distribution","resumen":"The present work compares two deformation techniques, rolling and Equal Channel Angular pressing (ECAP), and the response offered by three different materials that differ in Stacking Fault Energy (SFE): AA1010 Al, commercially pure Cu, and an austenitic stainless steel. The objective of this investigation is to study the effect of each deformation mode on tensile behavior, deformation mechanism, texture, and microstructure and to establish the influence of the stacking fault energy on said effects. The results show that the different strain paths of ECAP and rolling do not affect the strength, but rolling leads to an accentuated texture and thus to elastic and plastic anisotropy. This finding has practical relevance for micro manufacturing techniques. Furthermore, it is observed that lower SFE results in smaller domain size and higher dislocation density, which are microstructural details related to strength and to the work hardening capacity. Finally, both techniques are able to produce a high amount of high angle grain boundaries, a feature that characterizes refined microstructures. These processes operate at different strain rates; thus, in low SFE materials, a more effective grain fragmentation by deformation-induced twins is observed after the ECAP process.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239965,"idioma_id":4,"titulo":"The Spb method used to estimate crack extension for coiled tubings fracture toughness tests","resumen":"Coiled tubings are widely used in oil and gas industries. Fracture toughness test of coiled tubing is a challenge. Non-standard specimen has to be used due to its geometrical difficulties, ie small thickness and diameter. Taking into account these factors, fracture toughness resistance curves, J-R curves, of coiled tubings were determined using the Spb method for the first time. The separability parameter, Spb, is defined as the load ratio between two specimens at constant displacement, a precracked one that exhibits crack growth during its test and a blunt notched specimen with constant crack length when tested. Spb method, which uses Spb parameter, estimates stable crack growth in fracture toughness tests. It has been applied to different standardized specimen geometries. In this work, the method is applied to non-standard coiled tubing specimens. The geometry function was experimentally obtained testing four-point bending specimens. Stable crack growth results are compared to those measured using DC potential drop method used as reference method. Encouraging results were obtained.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239971,"idioma_id":5,"titulo":"La universidad en el Siglo XXI: nuevas configuraciones, tendencias de cambio y desafíos","resumen":"Durante las últimas décadas, resulta habitual hallar en la literatura de las ciencias sociales la permanente referencia a procesos de mundialización y globalización de la economía, las finanzas y la información en el contexto de las variaciones del sistema capitalista de países centrales y periféricos. Además, se asiste a un escenario de complejas relaciones entre la -universidad pública con diversos actores, esferas y entidades de la sociedad- muchas de las cuales se han transfigurado en respuesta a los mencionados procesos. En consonancia, las transformaciones epocales, demandan la resignificación de los esquemas de reflexión, así como de las herramientas teóricas disponibles y desde las que tradicionalmente se han abordado las problemáticas universitarias.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239972,"idioma_id":5,"titulo":"La muerte del arte y los nuevos modelos de producción en danza contemporánea","resumen":"Las clásicas teorías del arte y de la crítica del arte, aún válidas para dar cuenta del arte moderno, constituyen muy a menudo pobres recursos para analizar, explicar o legitimar las formas casi siempre desconcertantes de la creación actual. Esta situación particular inédita en la historia del arte occidental, corresponde a lo que se califica como des-definición del arte. ¿Cómo interpretar lo que se denomina des-definición del arte? En lugar de interrogarse en vano sobre qué es el arte y adaptar, bien o mal, su definición a cada irrupción de algo aparentemente incongruente, la filosofía analítica y pragmática, toma nota de las profundas modificaciones que afectan al estatuto de la obra de arte y del artista. Ya no se trata de hacer referencia a una esencia universal e intemporal del arte. De este modo se procura hallar los factores que permiten que un objeto cualquiera sea percibido o ?funcione? como obra de arte. El pretendido valor intrínseco de la obra, sus cualidades artísticas, su capacidad de suscitar sentimientos, no resultan adecuados para una eventual definición de la obra de arte. Más bien, habría que tomar en consideración el contexto filosófico y artístico en el cual aparecía el objeto que aspiraba al estatuto artístico. Asimismo, es importante considerar la intensión y el proyecto del artista, tal como se los puede percibir en determinado medio artístico.Renovar la teoría del arte y adaptar el discurso estético a esta situación inédita se impone como una necesidad. Por ende, es pertinente en este escrito que intenta aproximarse a lo contemporáneo de la llamada Danza Contemporánea, introducirnos en algunas de las teorías que intentan explicar esta nueva expresión creativa.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239973,"idioma_id":5,"titulo":"Triptico de la infamia de Pablo Montoya, la permanencia del desamparo","resumen":"El objetivo de este trabajo es analizar la tematización del desamparo y la obra de arte como espacio de denuncia de la violencia en la novela Tríptico de la infamia del escritor colombiano Pablo Montoya. A través de procedimientos constructivos basados en el juego con la intertextualidad y la recursividad que implica el trabajo del  pliegue, propio de la estructura del tríptico, la novela pone en escena una serie de relaciones entre obras y autores de la tradición de la literatura latinoamericana que también denuncian dichas problemáticas.  La hipótesis que articula esta lectura es que el armado intertextual de la novela y sus filiaciones permiten leerla como un núcleo en el que confluyen múltiples genealogías de la violencia desde las escrituras fundantes en la literatura latinoamericana como lo son las Crónicas de Indias a la literatura contemporánea. De esta manera, a través de un trabajo de lectura y reescritura, se denuncia esta problemática a través del tiempo, se habla del pasado pero a la vez se alude al presente donde el horror permanece.  La obra pone en escena la materia violenta que forma parte de la vida cotidiana y hace de la denuncia del horror, con los ejes en la matanza de indígenas americanos y la guerra religiosa en Europa, el motor de la escritura cuya base es una investigación que muestra un giro autoficcional por parte del autor y que, al mismo tiempo,  muestra el compromiso que asume Pablo Montoya como escritor.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239974,"idioma_id":5,"titulo":"Interrogar el pasado reciente más allá de las fronteras nacionales: entre lo local, lo trasnacional y las perspectivas comparadas","resumen":"Se trata de un artículo introductorio al dossier 'La historia reciente más allá de lo nacional: Cono Sur y Península Ibérica'. Aborda las distintas escalas de análisis en la investigación sobre el pasado reciente, que van desde lo local y lo regional a lo transnacional, con el objetivo de dar cuenta de nuevas agendas de investigación y nuevos problemas que vinculen ciertos principios metodológicos (como la articulación simultánea de escalas distintas) con otras formas de conocimiento como es el enfoque comparativo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239975,"idioma_id":5,"titulo":"Presentación al Dossier 'La Historia Reciente en la Argentina: problemas de definición y temas de debate'","resumen":"El texto es la presentación al dossier ´La Historia Reciente en la Argentina: problemas de definición y temas de debate´, realizada por sus editores por invitación y para la revista Ayer. Repasa algunos de los principales desarrollos de ese campo de estudios, así como los problemas y agendas de investigación, introduciendo a los artículos que integran el dossier.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239976,"idioma_id":5,"titulo":"Represión y terror de estado en la Argentina reciente: nuevos abordajes y perspectivas de análisis","resumen":"En los últimos años, los estudios sobre la represión en la historia reciente argentina vienen mostrando una vitalidad notable así como una agenda de renovadas perspectivas, temas y problemas. A los análisis más difundidos sobre la represión y la violencia política, se sumaron un conjunto de investigaciones sobre temas y casos que debaten periodizaciones, abordajes, conceptualizaciones e interpretaciones fuertemente instaladas. El artículo explora los principales nudos problemáticos que atraviesan esta línea de estudios, poniendo el foco en la cuestión del estado y sus agencias, con el objetivo de examinar dichos problemas a la luz de algunos recorridos analíticos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239978,"idioma_id":4,"titulo":"Bio-adhesives from soy protein concentrate and montmorillonite: rheological and thermal behavior","resumen":"The incorporation of different amounts of montmorillonite (MMT) to soy protein concentrate (SPC) was used to improve the performance of the bio-nano-adhesive obtained. X-Ray diffraction, rheology, thermogravimetric analysis and scanning electronic microscopy were carried out to characterize the adhesives, and dry and wet strength was used to determine the adhesion strength. In the rheological measurement, the incorporation of up to 3 wt% of MMT did not modify the consistency index values of the SPC, while an increase in the flow consistency index for higher concentrations can be observed due to a strong interaction between MMT and the protein. Besides, the flow point values increase four times with respect to the value obtained for SPC alone. The decomposition temperature of SPC increases with the addition of MMT, which provides a tortuous pathway that obstructs the diffusion of volatile products out of the bio-nano-adhesive. Further addition beyond 5 wt% led to the formation of agglomerates, as verified by SEM. Moreover, the roughness of the fractured surface of the matrix can explain the decrease of the net adhesion of the nano-particles to the SPC suspensions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239979,"idioma_id":4,"titulo":"Stratigraphy, geochronology, and paleoenvironments of Miocene - Pliocene boundary of San Fernando, Belén (Catamarca, northwest of Argentina)","resumen":"The Santa María-Hualfín Basin was proposed as a regional synchronous lithostratigraphic depocenter in the geological province of Northwestern Pampean Ranges, Northwestern Argentina. However, new 40Ar-39Ar dating indicates that deposits toward the east, in Santa María Valley (Santa María Department), areyounger than the western depocenter in San Fernando (Belen Department). Therefore, it would be more appropriate to study these valleys as separate basins, each one with its own tecto-sedimentary features.The east basin, named in this paper Villavil-Quillay, constitutes an elongated independent basin that developed along the front of the eastern Puna bordering with Papachacra and Durazno Ranges. This basin is composed of more than 3000 m of mudstone, sandstone, conglomerates, volcaniclastic and pyroclasticdeposits. Villavil-Quillay basin develops onto a peneplain of Precambrian and lower Cambrian rocks, most of which are metamorphic and granites rocks. The sedimentary fill consists of Cretaceous? and Cenozoic continental deposits. The Cenozoic record is composed of a) the Santa María Group (Miocene-Pliocene), formed by Las Arcas, Chiquimil, Andalhuala and Corral Quemado Formations, and b) the Punaschotter unit (Puna´s Gravels in German, Pleistocene). This study involves the Andalhuala, Corral Quemado and Punaschotter deposits cropping out in San Fernando area. The set of identified facies assemblage corresponding to the Andalhuala Formation shows a vertical variation of fluvial subenvironments,varying from permanent sandy braided rivers to gravel rivers and aeolian dunes culminating in an alluvial dry cycle. While facies assemblages of the Corral Quemado Formation allow inferring the development of ephemeral water bodies from secondary channels on the floodplain, the Punaschotter conglomerates indicate the development of gravel channels and bars. Three samples of tuffs interbeddedin the sedimentary levels of Andalhuala Formation were dated indicating that the Miocene-Pliocene boundary is represented in this area. The lower tuff beds, outcropping at the southwest of San Fernando Sur, provided an age of 5.59 ± 0.04 Ma (late Miocene, Messinian). The others tuffs beds, both outcropping at the west-northwest of San Fernando Norte and overlaying the first one, gave an age of 4.79 ± 0.15 Ma and 4.72 ± 0.08 Ma (early Pliocene, Zanclean), respectively. These absolutes ages, together with the results of a sedimentological analysis, indicate that westward from San Fernando River, much of the areas mapped as Corral Quemado Formation correspond to the Andalhuala Formation; while part ofthe area considered as Punaschotter unit must be assigned to Corral Quemado Formation. Also, a thick tuff bed, recognized at the contact of Corral Quemado and Punaschotter, was considered as the previous one dated in 3.66 Ma, in Puerta de Corral Quemado locality.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239981,"idioma_id":5,"titulo":"La construcción de instancias de juego con rasgos lúdicos en la educación física del nivel inicial","resumen":"El presente artículo posee como objetivo general comprender los procesos de construcción de las situaciones lúdicas en clases de Educación Física Infantil.     Se ha llevado adelante un diseño metodológico sustentado en los supuestos epistemológicos de la metodología cualitativa, siendo una investigación de tipo aplicada, produciendo la información empírica en base a un trabajo de campo desarrollado en el contexto natural. El método ha sido un estudio de caso instrumental, en base a un diseño exploratorio ? interpretativo, en el cual se ha desarrollado un proceso sistemático y longitudinal de 41 observaciones de clases de educación física, utilizando registros de notas de campo, video filmaciones y grabaciones de voz de los diálogos ocurridos entre el docente y los niños para recabar la información correspondiente, los cuales se unificaron en registros observacionales. La muestra ha sido de carácter no probabilística, deliberada e intencionada conformada por 32 niños y niñas de entre cuatro y cinco años y de un docente especialista en Educación Física Infantil.          La construcción de las situaciones lúdicas requiere de acciones conjuntas entre la participación guiada del docente y de niños percibidos y sentidos como jugadores atravesando fases de montaje y sostenimiento de lo lúdico en donde se exponen preferentemente ideas o reglas de carácter implícito y\/o explícito como proposiciones para jugar. Por tanto, en las situaciones lúdicas, los jugadores montan y estructuran la forma de juego preparando todo lo necesario para jugar y sobre todo van configurando un sentido no competitivo en sus modos de jugar.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239982,"idioma_id":4,"titulo":"Short-term chromium (VI) exposure increases phosphorus uptake by the extraradical mycelium of the arbuscular mycorrhizal fungus Rhizophagus irregularis MUCL 41833","resumen":"Hexavalent chromium is a potent carcinogen, while phosphorus is an essential nutrient. The role of arbuscular mycorrhizal fungi (AMF) in the uptake of P is well known and was also reported, at low levels, for Cr. However, it is unclear whether the uptake of Cr can impact the short-term uptake dynamics of P since both elements have a similar chemical structure and may thus potentially compete with each other during the uptake process. This study investigated the impact of Cr(VI) on short-term P uptake by the AMF Rhizophagus irregularis MUCL 41833 in Medicago truncatula. Bi-compartmented Petri plates were used to spatially separate a root compartment (RC) from a hyphal compartment (HC) using a whole plant in vitro culture system. The HC was supplemented with Cr(VI). Chromium(VI) as well as total Cr and P were monitored during 16 h within the HC and their concentrations determined by the end of the experiment within roots and shoots. Our results indicated that the uptake and translocation of Cr from hyphae to roots was a fast process: roots in which the extraradical mycelium (ERM) was exposed to Cr(VI) accumulated more Cr than roots of which the ERM was not exposed to Cr(VI) or was dead. Our results further confirmed that dead ERM immobilized more Cr than alive ERM. Finally our results demonstrated that the short exposure to Cr(VI) was sufficient to stimulate P uptake by the ERM and that the stimulation process began within the first 4 h of exposure.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239983,"idioma_id":5,"titulo":"¿Cómo no hablar de 'Derecho y Literatura'? Cinco tesis","resumen":"En un artículo ya famoso, Enrique E. Marí concluye que se puede hablar de?Derecho y Literatura?, pero en voz baja. En 1998, la Academia Argentina aún noestaba preparada para establecer este ?puente? interdisciplinario: 'A la Academia del Derecho, le va a costar mucho salir del estado de'ciego, sordo y mudo'. Mejor que un puente, prefiere un subterráneo que laconduzca, firme y segura, por una sola vía. Cuestión de defensa profesional.El puente, como a Monsieur Dupin y los positivistas ?que, en rigor, formanla Academia en la teoría del derecho? se les presenta como 'extraño'.Luego de la inspirada e insistente labor de Carlos Cárcova, Alicia Ruiz, ClaudioMartyniuk, Nora Wolfzun y Jorge Douglas Price, entre otros, llegó el momento dehablar a viva voz, de hablar en voz alta sobre ?Derecho y Literatura?. ¿Cómo nohablar de aquello que reclama a gritos por su lugar en los estudios jurídicos? La enseñanza del Derecho no puede seguir denegando ciertos aspectos decisivos del fenómeno que estudia; no puede seguir ensayando cómo no hablar de ?Derecho yLiteratura? porque ?aunque esto ponga en jaque las concepciones tradicionales? es necesario advertir que la Literatura atraviesa lo jurídico de un modo fundamental.En este artículo expondré diversas razones que justifican la necesidad de laurgente incorporación de los estudios ?Derecho y Literatura? como una asignaturaen los planes de estudios de las carreras de Abogacía de las universidades argentinas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239986,"idioma_id":4,"titulo":"On the extended stellar  structure around NGC 288","resumen":"We report on observational evidence of an extra-tidal clumpy structure around NGC,288from an homogeneous coverage of a large area with the Pan-STARRS PS1 database.The extra-tidal star population&nbsp; has been disentangled from that of the Milky Way field by using a cleaning technique that successfully reproduced the stellar density, luminosity functionand colour distributions of MW field stars. We have produced the cluster stellar density radial profile and a stellar density map from independent approaches, from which we found resultsin excellent agreement : the feature extends up to 3.5 times the cluster tidal radius. Previous works based on shallower photometric data setshave speculated on the existence of several long tidal tails, similar to that found in Pal,5.The present outcome shows that NGC,288 couldhardly have such tails, but favours the notion that interactions with the MW tidal fieldhas been a relatively inefficient process for stripping stars off the cluster. These resultspoint to the need of a renewed overall study of the external regions of Galacticglobular clusters (GGCs) in order to reliably characterise them. Hence, it will be possible to investigate whether there is&nbsp; any connection between detectedtidal tails, extra-tidal stellar populations, extent diffuse halo-like structures &nbsp;with the GGCs´ dynamical histories in the Galaxy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239988,"idioma_id":5,"titulo":"La quinua en el Noroeste Argentino","resumen":"Cuando se habla de quinua, la primera imagen que viene a la mente esla de coloridas plantas que iluminan paisajes desolados en el altiplano bolivianoy peruano, como las que muestra la fotografía puesta en la tapa delnúmero 138 de Ciencia Hoy, en el que dos artículos (citados al final entrelas lecturas sugeridas) describen las características históricas y actuales deun cereal (o más precisamente un seudocereal) nativo de los Andes llamadoChenopodium quinoa por los botánicos. Este artículo se refiere a su cultivo actualen el noroeste argentino.El cultivo de la quinua, domesticada inicialmente en la zona del lagoTiticaca hace unos cinco milenios, tuvo importancia entre las poblacionesprehispánicas del área andina y periandina, particularmente ?pero no solo?en tierras altas ubicadas en torno a salares y lagos, a más de 3500m sobreel nivel del mar, donde la especie prospera a pesar del frío y de la intensaradiación solar. El mapa muestra su diseminación entre dichas poblaciones,desde Colombia hasta el sur de Chile.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239989,"idioma_id":4,"titulo":"Multiphase Characterization of Cu-In-Sn Alloys with 17 at.% Cu and Comparison with Calculated Phase Equilibria","resumen":"Cu-In-Sn alloys are among the suggested materials to replace Pb-Sn alloys traditionally used in joining processes by the electronic industry. Thorough thermodynamic understanding is required for the selection\/design of adequate and efficient alloys for specific applications. Understanding the effects that high cost elements such as In have on microstructure and phase stability is imperative for industrial use. In this work ternary alloys were prepared by melting high purity elements (5N) for selected compositions of the 17 at.% Cu isopleth, and cooling down to reproduce process conditions. Chemical composition was determined using scanning electron microscopy equipped with electron probe microanalysis. Measurements of transition temperatures were done by heat-flux differential scanning calorimetry. We present a comprehensive comparison between our experimental results and phase diagram calculations using Liu et al. (J Electron Mater 30:1093, 2001) thermodynamic description based in the CALPHAD method, available in the literature.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239994,"idioma_id":5,"titulo":"Cueto o el nonsense. Versiones del crítico","resumen":"Este trabajo presenta una lectura de los ensayos de Sergio Cueto sobre el nonsense a partir del modo en que se configura en ellos el movimiento de la resistencia a\/de la teoría (de Man 1990). Se propone la hipótesis de que estos ensayos críticos ponen de manifiesto una teoría en obra del arte del nonsense, en tanto que actúan o ensayan la pregunta sobre la posibilidad\/imposibilidad de teorizar sobre el problema. Es allí donde la teoría falla, se niega o se ausenta, que el esfuerzo de teorización triunfa. La lógica de la resistencia a\/de la teoría se estructura en estos textos, ensayísticamente, como una más de las versiones del nonsense. El trabajo busca mostrar, además, el giro que introduce la versión del crítico respecto de otras lecturas canónicas y actuales, como las de Chesterton y Aira, en su esfuerzo ético por preservar la irreductibilidad de la imaginación nonsensical.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239997,"idioma_id":4,"titulo":"Quantum correlations and coherence between two particles interacting with a thermal bath","resumen":"Quantum correlations and coherence generated between two free spinlessparticles in the lattice, interacting with a common quantum phonon bath, are studied. The reduced density matrix is solved using the Markov approach. We show that the bath induces correlations between the particles. The coherence induced by the bath is studied, calculating off-diagonal elements of the density matrix, spatiotemporal dispersion, purity and quantum mutual information. We find a characteristic time-scale pointing out when this coherence is maximum.In addition, a Wigner-like distribution in the phase-space (lattice) is introduced as an indirect indicator of the quantumness of total correlations and coherence induced by the thermal bath. The negative volume of the Wigner function also shows a behavior which is in agreement with the time-scale that we have found. A Gaussian distribution for the profile of particles is not obtained, and interference patterns are observed as the result of bath-induced coherence.As the temperature of the bath vanishes, the ballistic behavior of the tightbinding model is recovered. The geometric quantum discord is calculated, to characterize the nature of the correlations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":239998,"idioma_id":4,"titulo":"Burden of Culture-Confirmed Pediatric Pneumococcal Pneumonia in Latin America and the Caribbean: A Systematic Review and Meta-Analysis","resumen":"Background:Pneumococcal pneumonia (PP) causes almost one infivedeaths in children younger than 5 years worldwide. In Latin Americaand the Caribbean (LAC), pneumonia causes 14% of all deaths.Although pneumococcal disease is a vaccine-preventable disease thataccounts for a significant proportion of this burden, the decision-making process to introduce pneumococcal conjugate vaccines inofficial schedules is still complex in LAC. Confirmed PP cases andepidemiology are the basis for broader projections.Objective:Togather all the information available in the LAC region to assistdecision makers.Methods:We performed a systematic review ofstudies of consolidating and culture-confirmed pediatric PP in LAC(2000?2016) using a generic academic Internet search and searchengines without language restrictions. Pairs of reviewers independ-ently selected and assessed the studies?methodological quality. Weanalyzed meta-information on pneumococcal serotypes availablefrom the SIREVA laboratory-based surveillance system.Results:A otal of 35 out of 750 initially identified studies were included. In theage group between 0 and 59 years, the incidence of culture-confirmedPP ranged from 10.2 to 43.0\/100,000 children, with a pooled incidenceof 20.4\/100,000 children (95% confidence interval 0.0?123.2). Mortalityranged from 0.4 to 5.7\/100,000 children, and the pooled mortality was2.9\/100,000 children (95% confidence interval 0.3?8.2). The pooledserotype distribution from surveillance data showed that serotypes14, 1, and 6B were the most frequent serotypes in LAC, all included inlicensed vaccines.Conclusions:Studies on confirmed pediatric PPwere scarce in LAC in 2000 to 2016. Epidemiology indicators andhealth resource use are still poorly defined.Keywords:child health, Latin America, pneumonia,Streptococcuspneumonia, systematic review.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240000,"idioma_id":5,"titulo":"Epidemiología y tratamiento previo a una hospitalización por insuficiencia cardíaca: el diagnóstico precoz como area de intervención. Resultados del Registro Argentino de Insuficiencia Cardíaca (REARGIC).","resumen":"La epidemiología y el tratamiento previo a una hospitalización por insuficiencia cardíaca (HIC) han sido poco caracterizados y pueden ser blancos de intervención. Objetivo: Evaluar las características clínicas y tratamiento empleado previo a una H-IC en Argentina.Método: El Registro Argentino de Insuficiencia Cardíaca (REARGIC) incluyó prospectivamente 1257 pacientes en 2 etapas: Mar.13-Feb.14 (N=913) y Dic.14-Mar.16 (N=344).Resultados: El 61% de la población tenía diagnóstico previo de IC (Dxpre), y comparados con el resto, presentó similar edad (67±16 años), menor frecuencia de mujeres (34.9 vs 40.9%, p=0.032), mayor prevalencia de factores de riesgo y comorbilidades. El cuadro clínico presentó mayor severidad en Dxpre comparado con el resto y la fracción de eyección del VI fue <50% (FEr) en 79,3 vs 49,8% (p<0.0001). El uso previo de drogas con beneficio demostrado (DBD) fue diferente en los grupos con y sin Dxpre en inhibidores de enzima de conversión o bloqueante del receptor de angiotensina: 74.9 vs 60.5% (p<0.0001), betabloqueantes: 77.3 vs 40.7 (p<0.0001), antagonistas del receptor mineralocorticoideo: 57.6 vs 17% (p<0.0001), así como la administración de2-3 de estas drogas: 74 vs 34.4% (p<0.0001). En el análisis multivariado, los predictores independientes del empleo de 2-3 DBD fueron: hipertensión (OR=1.54; IC=1.10-2.16; p 0.013), bloqueo de rama izquierda (OR=1.56; IC=1.06-2.29; p 0.023), FEr (OR=2.22; IC=1.60-3.08; p<0.0001) y Dxpre (OR=2.22; IC=1.41-3.49; p=0.001).Conclusión: Dos tercios de las H-IC en Argentina tenían Dxpre. Si bien el cuadro clínico fue más severo y el tratamiento previo fue mejor en estos casos, aquellos sin Dxpre presentaban predictores de IC. Estos resultados sugieren que la intervención pre-H-IC, a través de identificación temprana y optimización terapéutica, podrían reducir la progresión a la descompensación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240002,"idioma_id":5,"titulo":"Regulación de carga frutal en cerezo Royal Dawn: efecto en el rendimiento, crecimiento vegetativo y calidad del fruto.","resumen":"El objetivo del trabajo fue caracterizar el comportamiento productivo y evaluar el efecto de la regulación de la carga frutal sobre el rendimiento, el crecimiento de brotes y la calidad de los frutos  de cerezo cv. Royal Dawn, en la provincia de Mendoza, Argentina, en una plantación de 4 años de edad. El primer año se estudió el comportamiento productivo sin manejo de la carga. En el segundo año los tratamientos fueron: Poda (eliminación del 35 % de madera frutal, P); Poda + extinción del 30 % de los ramilletes (P+E30%); Poda + extinción del 50% de los ramilletes (P+E50%) y Extinción del 30% de los ramilletes (E30%). El tercer año se midió la longitud de los brotes en cada tratamiento. En el año 1 el rendimiento promedio fue muy alto: 15,05 kg por planta; aunque el 99,86% de los frutos presentó un tamaño no exportable &#8804; 24mm. En P+E30% y P+E50 % se redujeron marcadamente los rendimientos en relación a P y a E30%.  Todos los tratamientos de reducción de la carga mejoraron la distribución de calibres y aumentaron la proporción de frutos >24 mm. En P+E30% y P+E50% disminuyó a niveles muy bajos la fruta &#8804;24 mm: 3,68% y 1,92% respectivamente, y además en P+E50% se obtuvo 18,05% de cerezas >28mm. En el tratamiento de menor carga P+E50%  hubo mayor crecimiento de brotes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240007,"idioma_id":5,"titulo":"Ante el archivo latinoamericano. Dos novelas rusas de José Manuel Prieto","resumen":"Artículo de 8780 palabras. En prensa. Se adjunta artículo y carta de aceptación para número misceláneo. En la narrativa de José Manuel Prieto, la idea de traducción de la vida en el Este, como mundo desconocido y diverso, apunta a indagar qué elementos literarios utilizar para que tenga eficacia dicha transmisión. De allí deriva la idea de una escritura que toma un distanciamiento, mediante una forma específica. Prieto toma al archivo como forma de la novela: concretamente, un archivo de epistolarios en 'Livadia' y una enciclopedia, en 'Enciclopedia de una vida en Rusia'. Sin embargo, la exploración de estos formatos conduce, en su poética, hacia procesos más profundos del archivo latinoamericano. Mi hipótesis es que a través de los paisajes euroasiáticos y la recuperación de la biblioteca rusa prerrevolucionaria, la escritura de Prieto vuelve sobre dos grandes tradiciones: la metamorfosis barroca y el cosmopolitismo modernista. Estas recuperaciones se vuelven sumamente importantes en el contexto literario cubano de los años noventa porque dialogan con las discusiones acerca de la relación entre los intelectuales y el Estado.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240009,"idioma_id":5,"titulo":"Supervivencia de las cucarachas. Kafka en Cuba a finales de siglo XX","resumen":"El artículo aborda tres recuperaciones kafkianas en Cuba durante los años ochenta y noventa estableciendo una serie entre el ensayo de Reinaldo Arenas sobre Virgilio Piñera, 'La isla en peso con todas sus cucarachas', con la poesía y la prosa de Rolando Sánchez Mejías y Carlos A. Aguilera, y sus textos en Diáspora(s), la revista que ambos coordinaron, entre 1997 y 2002. Si la obra de Kafka funciona como llave de paso a un pensamiento que desbarata los límites de lo humano (Yelin 2015), mi hipótesis sostiene que su lectura en la literatura de estos autores habilita una figura de escritor anómala (el escritor-bicho), cuestión relevante en el contexto de crisis de la figura del Hombre Nuevo, a la vez que abre nuevas cartografías para el imaginario cubano.(Aclaración: si bien el artículo se halla incluido en el dossier que armamos con la Dra. Julieta Yelin, fue aprobado después de ser sometido a proceso de evaluación de doble ciego, como cualquier otro artículo, según las pautas de la Revista)","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240011,"idioma_id":5,"titulo":"A la escucha de Diadema","resumen":"El ensayo aborda una pregunta sobre la voz en la teatralidad de Marosa Di Giorgio, a partir de algunas experiencias de la escucha de 'Diadema', su recital teatral de poesía que también grabó en disco en el sello Ayuí, en 1994. Si, como sostiene Alain Badiou, el teatro piensa, resulta interesante investigar qué 'pensaban' esas performances de Marosa Di Giorgio, qué ideas arrojaban acerca de la autobiografía y el ritual, acerca de la lengua y la poesía en voz alta.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240012,"idioma_id":4,"titulo":"Pollen morphology and its relation with meiotic irregularities in ten species of Campuloclinium (Eupatorieae, Asteraceae)","resumen":"Pollen grains of ten species of Campuloclinium (Eupatorieae, Asteraceae) are described and illustrated using light and scanning electron microscopy. The species included in this study are C. burchelli, C. campuloclinioides, C. chlorolepis, C. hirsutum, C. irwinii, C. macrocephalum, C. megacephalum, C. parvulum, C. purpurascens and C. riedelli. Pollen grains of Campuloclinium are typically radially symmetric, echinate, tectate, oblate-spheroidal to prolate-spheroidal (P\/E ratio: 0.94&ndash;1.10). Pollen is mostly triaperturate, but tetraaperturate or biaperturate pollen also occurs in some species. The pollen diameter was highly variable ranging from 10.54&nbsp;&micro;m to 36.18&nbsp;&mu;m. The significance of the variation in type and size of pollen is discussed in relation to diverse meiotic abnormalities and possible reproductive apomictic processes within the polyploid species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240013,"idioma_id":4,"titulo":"Meiotic behaviour and B chromosomes in Argentine populations of Chrysolaena verbascifolia (Vernonieae: Asteraceae)","resumen":"Four populations of Chrysolaena verbascifolia (Vernonieae: Asteraceae) from localities in Argentina were cytologically analysed for meiotic behaviour and pollen viability. This is the first meiotic analysis in the species. All were diploids with 2n = 2x = 20 and all showed quite regular meiotic behaviour. We also report the occurrence of accessory chromosomes in all the populations of the species. The majority of the populations displayed regular bivalent formation during late prophase stages and metaphase I, and chromosome segregation at anaphase. However, some chromosomal irregularities were recorded, mainly during meiosis I, including univalents, out-of-plate chromosomes and precocious segregation in metaphase, and laggards and chromatin bridges in anaphase. The B chromosomes and abnormal behaviours of the chromosomes during meiosis observed did not affect pollen development in these taxa, as viability was always high.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240015,"idioma_id":5,"titulo":"Algunos aspectos sobre reproducción en asnos (Equus asinus).","resumen":"Los asnos (Equus asinus) pertenecen al Orden  Perissodactyla, Familia Equidae,  que incluye al género Equus. El asno doméstico usualmente pesa entre 80 y 480 kg, con una alzada que ronda los 80 a 160 cm. Pueden vivir entre 30 a 35 años y estar activos hasta una avanzada edad. En general son valorados por su facilidad de cuidado y su resistencia tanto física como a enfermedades. Diferentes culturas y pueblos de la antigüedad hacían un uso mucho más variado de los asnos de lo que actualmente ocurre. Además de su utilidad como fuerza de trabajo en agricultura, comercio, transporte y milicia, se empleaban su cuero, carne y leche. Esta leche es la más parecida a la humana y fue valorada por su contenido en azúcares y proteínas, que la hacía apta para niños con ciertas alergias a la leche de vaca y otras alteraciones gastrointestinales. En Europa central son vistos principalmente como animales de recreación o eventualmente empleados en programas de terapia asistida con animales. Hoy en día el uso de esta especie ha disminuído. No obstante, en los últimos años, los productos lácteos y cárnicos de asno son comercializados en mercados gourmets o como productos dietarios específicos (Kugler et al., 2008). La medicina china utiliza aminoácidos y proteínas provenientes del cuero de los asnos por sus propiedades antioxidantes. En nuestro país se desarrolló la raza de asnos Remonta Argentino utilizando 3 razas europeas y una americana. El registro genealógico lo lleva la Sociedad Rural Argentina y son muy  importantes para la producción de mulas necesarias para el ejército, especialmente en la zona de montaña. Además se utilizan para el turismo y como animal de carga para el transporte de materiales y equipos durante el ascenso de los andinistas. Por todo lo antedicho, resulta de sumo interés para investigadores del INITRA desarrollar una línea de investigación en esta especie, abordando la aplicación de biotecnologías reproductivas para una comprensión más completa de la fisiología reproductiva.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240016,"idioma_id":5,"titulo":"El aula virtual como espacio de construcción colectiva de conocimiento para la gestión participativa de Conflictos Ambientales","resumen":"El objetivo del presente artículo es reflexionar sobre una metodología de gestión del territorio, devenida en herramienta pedagógica: el Taller de Integración de Contenidos. El mismo se lleva a cabo en el marco del Diploma Superior en Conflictos Ambientales y Planificación Participativa, desde la plataforma virtual de la FLACSO-Argentina. Inicialmente se caracterizan las potencialidades de la Metodología de Planificación Participativa y Gestión Asociada para la gestión de conflictos ambientales. A continuación se enuncia una tríada de cuestiones consideradas como desafíos u oportunidades que surgen al introducir la dinámica de la metodología en el campo de la educación virtual. Luego se evalúa el Taller de Integración de Contenidos como herramienta pedagógica, observando su capacidad de producir conocimiento de manera colectiva y consensuada. Finalmente se proponen conclusiones que sirven de base para el diseño de una estrategia pedagógica recorriendo un camino que parte desde el campo de la gestión hacia el campo de la educación. Dicha articulación incorpora una mayor riqueza al debate, a la reflexión y a la transferencia de conocimientos en torno a diferentes experiencias territoriales, promoviendo la implementación de prácticas instituyentes que avancen más allá de las competencias  disciplinares propias de cada campo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240018,"idioma_id":5,"titulo":"Evaluación de la calidad del ADN espermático en camélidos sudamericanos y otras especies domésticas.","resumen":"Anormalidades en el material genético pueden expresarse por defectos en la maduracióno condensación nuclear, rupturas del ADN y anormalidades cromosómicas. Los parámetros de rutina  utilizados  para  evaluar  el  semen  (movilidad  espermática,  concentración,  viabilidad, funcionalidad de membranas y morfología) no reflejan la calidad  del ADN espermático. Esto cobra importancia para las técnicas de reproducción asistida, particularmente en la inyección intracitoplasmática de un espermatozoide en la que espermatozoides con genomas anormales pueden  alcanzar  el  material  genético  del  ovocito.  Se  postula  que  tres  factores  pueden  estar involucrados  en  la  etiología  del  daño  del  ADN:  estrés  oxidativo,  aberraciones  en  el empaquetamiento  de  la  cromatina  y  apoptosis.  Varias  técnicas  han  sido  utilizadas  para estudiar los defectos del ADN. A modo general, las técnicas de evaluación de ADN pueden ser divididas en 2 grupos: aquellas que evalúan el grado de condensación o compactación de la cromatina  y  aquellas  que  miden  el  grado  de  fragmentación  del  ADN.  Muchas  de  estas técnicas   son   laboriosas,   costosas   y   algunas   dependen   de   enzimas   cuya   actividad   y accesibilidad a  las roturas de ADN pueden ser irregulares. En este artículo se comenta sobre el  desarrollo  y  puesta  a  punto  de  varias  de  las  técnicas  de  evaluación  de  la  cromatina espermática en camélidos sudamericanos (CSA) y otras especies domésticas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240023,"idioma_id":5,"titulo":"'La decisión de producción de las empresas agrícolas en las provincias de Buenos Aires, Córdoba y Santa Fe'","resumen":"Argentina tiene uno de los territorios más extensos del planeta, con variedad de climas, suelos, y una gran diversidad étnica, en la que el agro cumple un papel fundamental como integrador. Tiene efectos estructurantes sobre el territorio y sus regiones; ocupa espacios e impulsa el desarrollo regional, favoreciendo nuevos emprendimientos, reteniendo a la población residente en sus lugares de origen y generando empleo en el interior del país. Entre los cultivos más importantes se encuentran la soja, actualmente el cultivo extensivo más relevante en la región y le siguen en orden de importancia, el maíz y el trigo. Una de las herramientas que posee el productor agropecuario al momento de decidir qué producir, ante la diversidad de cultivos posibles, es el margen bruto. En éste se compara el valor bruto de producción con los costos directos provenientes de la actividad. Este instrumento es uno de los más utilizados, debido a la fácil interpretación e instrumentación, permitiéndole al productor planificar, hacer un seguimiento y controlar su producción. Siguiendo a Barberis et al. (2017), manifiestan que a partir de la década de 1950, especialistas en Administración Rural elaboraron la metodología del análisis por márgenes, especialmente útil en empresas multiproducto, en las cuales las distintas producciones compiten por el uso de los recursos del establecimiento. De esta manera, el indicador económico de cada actividad es el Margen Bruto (generalmente expresado por hectárea, por ser la tierra el recurso productivo más limitante). Este tipo de análisis se denomina parcial, por evaluar a las actividades en forma independiente y considerar sólo los costos que le son directamente atribuibles. Luego, en función de la participación de cada actividad en la empresa, es posible obtener el resultado total de la misma. El término actividad puede estar definido por un proceso productivo completo, como por una parte de esos. El objetivo del trabajo es analizar, si el productor toma decisiones de producción en virtud de los cálculos de margen bruto que realiza al momento de sembrar o hay otros factores que influyen como la diversidad y alternancia de los&nbsp; cultivos; pronósticos climáticos, problemas de comercialización, expectativas de la política sectorial, tecnología y otros factores. Para ello se han seleccionado los cultivos de maíz, trigo y soja de primera; relacionando su producción, precio en dólares, margen bruto, en las diferentes zonas delimitadas para su estudio: Norte de Buenos Aires y Sur de Santa Fe, Sur de la provincia de Entre Ríos, Sudeste de Buenos Aires, Sudoeste de Buenos Aires y Sur de la provincia de Córdoba; durante el período de análisis que va desde el 2010 al 2016 inclusive. Se identificaron dichas regiones debido a que las condiciones climáticas, ecológicas, hídricas, de suelo; hacen que sean tierras aptas para los cultivos bajo análisis. Más allá de las similitudes mencionadas, la producción de maíz, trigo y soja en dichas provincias representan el mayor porcentaje a nivel país. La suma del área cosechada de las cuatro provincias representa sobre el total del país, los siguientes porcentajes respectivamente, el maíz el 66,09%,&nbsp; el trigo el 78,79% y la soja el 84,01%.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240026,"idioma_id":4,"titulo":"Ambient Species Density and Gas Temperature Radial Profiles Derived from a Schlieren Technique in a Low-Frequency Non-thermal Oxygen Plasma Jet","resumen":"A quantitative interpretation of the schlieren technique applied to a non?thermal atmospheric?pressure oxygen plasma jet driven at low?frequency (50 Hz) is reported. The jet was operated in the turbulent regime with a hole?diameter based Reynolds number of 13800. A parallel?beam mirror schlieren system was used in the research. The technique allowed measuring the temporally?averaged values of the gas temperature of the jet by processing the gray?level contrast values of digital schlieren images. The penetration of the ambient air into the jet due to turbulent diffusion was taken into account. The calibration of the optical system was obtained by fitting the sensitivity parameter so that the oxygen fraction at the nozzle exit was unity. The radial profiles of the contrast in the discharge off case were quite symmetric on the whole outflow, but with the discharge on, relatively strong departures from the symmetry were evident in the near field. The gas temperature of the jet was relatively high, with a maximum departure of about 55 K from the room temperature; as can be expected owing to the operating molecular gas. The uncertainty in the temperature measurements was within 6 K, primarily derived from errors associated to the Abel inversion procedure. The results showed an increase in the gas temperature of about 8 K in the region between 0 and 5 mm away from the nozzle exit; thus suggesting that some fast?gas heating (with a heating rate &#61566; 0.3 K\/&#61549;s) still occurs in the near field of the outflow.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240027,"idioma_id":5,"titulo":"Proteínas de la saliva en relación con la caries dental en niños","resumen":"Las proteínas salivales desempeñan un papel importante en los procesos fisiológicos y las enfermedades crónicas del cuerpo humano. El nivel de proteínas salivales cambia con numerosos estados fisiológicos y condiciones patológicas. Uno de los procesos patológicos acompañados por cambios en las proteínas salivales es la caries. Así, el objetivo de éste estudio de revisión fue evaluar la relación entre las proteínas salivales y la caries dental en niños y sus potenciales aplicaciones terapéuticas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240031,"idioma_id":5,"titulo":"Posible violación a los derechos humanos. No hay razones para bajar la edad de punibilidad","resumen":"No se puede bajar la edad de imputabilidad\/punibilidad sin violar derechos humanos; no es recomendable que niñ@s de los sectores más desaventajados se críen en las cárceles; no es necesario ni sirve para lo que se propone; no resuelve ningún problema sino que generará más; e irá hasta contra los derechos de las propias víctimas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240032,"idioma_id":5,"titulo":"'DETENCIONES EN LA VÍA PÚBLICA. ANÁLISIS CONVENCIONAL? ES NECESARIO Y URGENTE REFORMAR LA LEGISLACIÓN PAMPEANA","resumen":"Lo primero que podemos decir para iniciar con el tema que nos hemos propuesto,es que en el estado de derecho constitucional debería existir un abanico de derechoshumanos y de mecanismos dispuestos para su garantía y no afectación que el estadoargentino debe cumplir. Para su re afirmación existen diversos mecanismos, entre ellosdictar leyes acordes al piso convencional-constitucionalmente dispuesto, y realizar sobrelas dictadas el control de constitucionalidad y convencionalidad que obliga a los órganosestatales a compatibilizar normas y prácticas (que no cumplan con ese piso) con lasnormas del máximo nivel de validez, en particular a las personas que ejercen la judicatura,según surge de la jurisprudencia de la CSJN y CorteIDH en la materia2.En el ámbito del ejercicio del poder punitivo suele manifestarse de manera groserala diferencia entre esas normas y la realidad, desfasaje entre ser y deber ser por ciertosiempre existente -en más o en menos- en los estados de derecho históricos, pues losestados ideales no existen debido a una multiplicidad de factores, entre ellos y conrespecto al sistema penal, las dinámicas de poder en las pulsiones permanentes entre elestado gendarme o de policía y el estado de derecho3.Es grave cuando el corrimiento hacia el estado vertical se da en el ámbito de lasprácticas del ejercicio de poder punitivo, pero lo es más cuando la incompatibilidad con lasobligaciones internacionales y constitucionales se manifiesta directamente en las normasjurídicas aplicables, puesto que el ordenamiento jurídico aparece legitimando prácticascontrarias a los derechos humanos, en un contrasentido insoportable que resulta de unagravedad institucional supina e inexcusable. Por una parte, al interior del Estado seencuentran dispuestas las agencias necesarias para que ello no suceda (de creación,aplicación y control de normas constitucionales y convencionales) y en otra parte delmismo (des) ordenamiento jurídico existen normas que disponen un sentido contrario, por1 Docente Universidad Nacional de La Pampa, miembro de la Asociación Pensamiento Penal y Defensor Oficial en loPenal, de Ejecución y Faltas de Santa Rosa, La Pampa.2 CorteIDH 'Almonacid Arellano vs Chile' (2006), 'Radilla Pacheco vs México' (2009) y ?Cabrera García y MontielFlores vs México? (2010), entre otros. CSJN ?Giroldi? (1995), ?Simón? (2005), ?Videla? (2005), 'Mazzeo' (2007),?Arriola? (2009), ?FAL? (2012) y 'Rodríguez Pereyra'(2012), entre otros.3 Para más detalles Alberto Binder ?Introducción al Derecho Procesal Penal?. AD-HOC. 5ª edición. Bs.As. 2009.lo cual es necesario verificar su validez.En La Pampa ello existe en varias temáticas, por ejemplo en materia deresponsabilidad penal adolescente, pero no nos ocuparemos de ello aquí4, sino de lasnormas que facultan detenciones de personas en la vía pública, las cuales autorizanprocedimientos contrarios al derecho a la libertad y no respetan la Constitución Nacional,la Provincial, fallos de la CSJN y una multiplicidad de reglas, normas y fallosinternacionales y hasta condenas contra Argentina (Caso ?Bulacio? por ejemplo).Y cuando pareciera que la contrariedad jurídica y conceptual no puede ser másfrontal, nos encontramos con que la más utilizada para legitimar arbitrariedades en el usodel poder coercitivo en la vía pública a cargo de funcionarios públicos, se trata de unanorma (no) jurídica de facto de la última dictadura cívico-militar. Broche de oro para elcomplejo normativo que pondremos bajo la lupa.Con el presente aporte pretendemos visibilizar la cuestión y sentar las bases parael establecimiento de normas respetuosas de los derechos humanos, adecuada a losestándares constitucionales e internacionales vigentes, pues tales normas seguiránproduciendo -entre otras- dos cuestiones de extrema gravedad: la legitimación deprácticas violatorias de los derechos humanos en la gestión del espacio público con unsinfín de víctimas y el riesgo de responsabilidad internacional del estado argentino porculpa de La Pampa.Entendemos que la reforma necesaria y urgente en este campo del (des) ordennormativo no se asienta sólo sobre la obligación formal de adecuar el conjunto de leyespara dotarlo de coherencia y validez sino que debe tener como eje principal a la personaen tanto ser humano integralmente considerado y de una dignidad y complejo dederechos inalterable como principio central y general (Art. 1 de la CADH). Por ello lainterferencia en el control y gestión de los espacios públicos de convivencia debería seren medidas estrictamente necesarias y adecuadas a los límites constitucionales yconvencionales pre dispuestos por las normas de mayor jerarquía, y precisamente porello, obligatorias para su aplicación excluyente de las de menor nivel jerárquico si secontraponen, máxime como las que veremos a continuación que resultan, en casos,enteramente incompatibles con las superiores.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240034,"idioma_id":5,"titulo":"El derecho humano a la educación para las personas privadas de su libertad y sobre cómo la prisión incluye otras privaciones degradantes de la subjetividad y redefine los derechos.","resumen":"Preliminarmente diremos que,si bien se ha escrito mucho respecto del tema del derecho a la educación en contextos de encierro, nos ceñiremos aquí al análisis de la recepción estatal del derecho a la educación en cuanto derecho humano a nivel supranacional por el Pacto Internacional sobre los Derechos Económicos, Sociales y Culturales (PIDESC) y otras normas y reglas internacionales, nacionales y locales, a fin de describir troncal mente ese derecho y sus implicancias en cuanto tal, en general, y respecto de las personas privadasde su libertad por conflictos penales, en particular, para luego atravesar esas lógicas del deber ser con la recepción en el mundo del ser -cualitativa y cuantitativa mente- a fin de contrastar lo que creemos inicialmente, está muy distante de coincidir.Trataremos de esbozar al final algunas conclusiones en relación a la temática propuesta, con el fin de visibilizar algunas cuestiones que obligan a la re formulación de políticas públicas y prácticas que obstaculizan el derecho a la educación de las personas privadas de su libertad a causa de conflictos penales","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240035,"idioma_id":5,"titulo":"Pago a cuenta del impuesto a las ganancias establecido por Ley 27264. Tratamiento contable en el marco de las NCPA y las NIIF","resumen":"Se analiza el tratamiento contable del beneficio fiscal instrumentado mediante ley 27264, evaluando sus consecuencias en el campo del impuesto diferido en el marco de las normas contables argentinas distintas de la RT 26, de las NIIF y de el tópico 740 de USGAAP.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240036,"idioma_id":4,"titulo":"Changes in the carbohydrate expression in cattle and buffaloes infected with the abortigenic protozoan Neospora caninum","resumen":"Carbohidrate pattern in the placenta was studied in different species showing a great variation between species. The sacharydes of the surface glycoconjugates are important to the adhesion between conceptus and uterus. Besides, reproductive diseases as tritrichomonosis and campylobacteriosis generate changes in this pattern in cattle. The aim of this study was to characterize the saccharide in placenta of cattle and buffaloes after experimental infection with the abortigenic protozoan Neospora caninum (N. caninum) at early gestation by lectinhistochemistry.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240037,"idioma_id":4,"titulo":"An Ibero-American inter-laboratory trial to evaluate serological tests for the detection of anti-Neospora caninum antibodies in cattle","resumen":"We carried out an inter-laboratory trial to comparethe serological tests commonly used for the detection of specificNeospora caninum antibodies in cattle in Ibero-American countries. A total of eight laboratories participatedfrom the following countries: Argentina (n = 4), Brazil (n = 1),Peru (n = 1), Mexico (n = 1), and Spain (n = 1). A blind panelof well-characterized cattle sera (n = 143) and sera representativeof the target population (n = 351) was tested by sevenin-house indirect fluorescent antibody tests (IFATs 1?7) andthree enzyme-linked immunosorbent assays (ELISAs 1?3;two in-house and one commercial). Diagnostic performanceof the serological tests was calculated and compared accordingto the following criteria: (1) the BPre-test information,^which uses previous epidemiological and serological data;(2) the BMajority of tests,^ which classifies a serumas positiveor negative according to the results obtained by most testsevaluated. Unexpectedly, six tests showed either sensitivity(Se) or specificity (Sp) values lower than 90%. In contrast,the best tests in terms of Se, Sp, and area under the ROC curve(AUC) values were IFAT 1 and optimized ELISA 1 andELISA 2. We evaluated a high number of IFATs, which arethe most widely used tests in Ibero-America. The significantdiscordances observed among the tests regardless of thecriteria employed hinder control programs and urge the useof a common test or with similar performances to either theoptimized IFAT 1 and ELISAs 1 and 2.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240038,"idioma_id":5,"titulo":"¿La violencia doméstica puede ser un mecanismo de tortura? ¿Y ello coadyuvar a reducir el poder penal sobre víctimas? El caso Y.P. de La Pampa","resumen":"En el presente trabajo trataremos someramente de abordar la temática relativa al entendimiento de la violencia doméstica por cuestiones de género como una de las modalidades de la tortura y si ello puede servir para reducir el poder punitivo materializado sobre víctimas de violencia de género diacrónica: a las obligaciones del Estado que se derivan de ese entendimiento adecuado, a la aplicación del derecho con una perspectiva de género en clave de derechos humanos, y, en especial, a la obligación estatal de actuar con la debidadiligencia para evitar que esos tipos de violencia se sucedan, agraven y reproduzcan, máxime cuando ya han sido detectados y abordados por organismos públicos, aún cuando los agresores fuesen particulares.Por último, aplicaremos tales estándares al caso Y. P. ocurrido en La Pampa en el año 2012, en el cual podremos ver que se ha verificado la intervención ineficaz de una multiplicidad de agencias pre-judiciales en relación a las lógicas que aquí trataremos en torno a una eficaz prevención, investigación, sanción, reparación y erradicación de ese tipo de violencia, y luego la materialización del poder penal sobre una mujer víctima de violencia de génerodiacrónica que actuó por propia mano contra su agresor.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240040,"idioma_id":5,"titulo":"EVALUACIÓN DEL GENOTIPO MAGRARIO COMO PROGENITOR EN CRUZAMIENTOS CON OTRAS RAZAS OVINAS","resumen":"En la producción de carne ovina en Argentina, así como en otros países de Latinoamérica, existe escasa tradición para la comercialización de reses de corderos pesados con bajo tenor de grasa. Un nuevo genotipo cuya marca registrada es Magrario (M®) fue obtenido por cruzas absorbentes de la raza Ideal (Polwarth) hacia la raza Texel en el Campo Villarino de la Facultad de Ciencias Agrarias de la UNR. Este genotipo no deposita grasa en la res ni aún en condiciones de confinamiento posdestete. En la presente experiencia se compararon machos y hembras de este genotipo con otras razas frecuentes en la Pampa Húmeda tales como Ideal (I) y Hampshire Down (HD) y con los cruzamientos (M®xI), (HDxM®) y (HDxI). Todos estos genotipos fueron evaluados en confinamiento en dos meses posdestete. Se evaluó también Peso Inicial (PI) Peso Final (PF), Aumento Medio Diario (AMD) y el AMD relativo (AMDr) como una estimación de la eficiencia de conversión. No se encontraron diferencias significativas ni en PF ni AMDr entre las cruzas. También se aplicaron técnicas de ultrasonido para evaluar Grasa Subcutánea (GS) y Grasa Perimuscular GP) en el m.Longissimus dorsi.  Se encontraron diferencias significativas (p < 0,001) entre los machos M® y HD para GS (M® = 0,52 y HD = 0,81). La cruza (HD x M®) tuvo valores intermedios entre ambos progenitores, GS = 0,65, mostrando una reducción de 20% respecto a HD, siendo los valores similares en hembras. Con las variables evaluadas se realizó un análisis de agrupamiento cuya correlación cofenética fue 0,85 en los machos y 0,80 en las hembras, donde las cruzas agrupaban cerca de M®, exceptuando (M®xI). Esta experiencia demostró que el genotipo Magrario puede ser utilizado como progenitor en cruzamientos para producir corderos cruzas con menores depósitos grasos en condiciones de suplementación posdestete.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240045,"idioma_id":5,"titulo":"Evaluación de colágeno tipo I en dos razas ovinas a partir de muestras de músculo glúteo medio obtenidas in vivo","resumen":"La terneza es el factor de calidad de la carne más importante y más variable. Tradicionalmente, en las investigaciones para evaluar la terneza de la carne bovina se utilizan ya sea la cuchilla o guillotina de Warner-Bratzler, que mide la fuerza (resistencia) de corte del músculo estudiado, o paneles de catadores. Sin embargo, estos análisis insumen mucho tiempo, dinero y se realizan postmortem. Al igual que los otros parámetros que definen la calidad de la carne, la textura y terneza dependen de numerosos factores relacionados con la producción y el manejo previo y posterior al sacrificio. El objetivo del presente trabajo fue evaluar la cantidad de colágeno intramuscular de tipo I en muestras de músculo Glúteo medio (músculo locomotor) obtenidas in vivo, en dos razas de la especie ovina, Texel y Criolla. Se empleó una muestra aleatoria de 10 animales de 2 años de edad de cada raza, utilizando la técnica histológica de Picrosirius-red modificada para obtener la cantidad de colágeno intramuscular de tipo I. En el músculo Glúteo medio en  ovejas de dos años de edad, no se encontraron diferencias entre las razas Texel y Criolla en cuanto a las fibras colágenas (colágeno tipo I), tampoco se detectó correlación entre el peso y las fibras, siendo más pesadas las Texel.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240047,"idioma_id":5,"titulo":"Escribir sin papel. Una experiencia no presencial en talleres de escritura literaria","resumen":"Entregado en septiembre de 2017. Este artículo presenta la experiencia de los Talleres de Iniciación a la Escritura Literaria Formas Breves (Universidad del Salvador, 2001-2017), en lo que hace a sus fundamentos en el momento de producción y diseño de su dinámica, en el que se investigó la relación con la modalidad precursora: los talleres literarios presenciales, y su recorrido y transformación en el Taller de Escritura Creativa. Se trata de una propuesta a distancia, en una plataforma on line, dirigida a estimular la producción escrita, a través de la lectura de textos ficcionales y de algunos textos teóricos que proporcionan herramientas para reconocer estrategias que puedan ser objeto de apropiación y transformación en el momento de escribir, a partir del desafío que supone la confrontación con una consigna. Los materiales del taller fueron pensados como una ?máquina? de generar propuestas de lectura y escritura, y como un espacio de observación de la mecánica de funcionamiento de un texto propio o ajeno. Una máquina que estimule la producción escrita y que permita la reflexión y el intercambio sobre el proceso de escritura.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240048,"idioma_id":5,"titulo":"ANÁLISIS ESPACIAL DE LA MORBILIDAD URBANA EN ADULTOS MAYORES, TANDIL 2011-2014","resumen":"El análisis de la distribución espacial de las enfermedades en el ámbito urbano representauna preocupación reciente en los países centrales. Analizar, puntualmente la salud en los adultosmayores, permitirá detectar situaciones de vulnerabilidad a la que esta población se enfrentadiariamente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240051,"idioma_id":4,"titulo":"Modeling respiration rate of soybean seeds (Glycine max) in hermetic storage","resumen":"The dynamic of oxygen (O2) and carbon dioxide (CO2) concentration was characterized in soybean (Glycine max (L.)) samples hermetically stored in glass jars at 15, 25 and 35°C and 13, 15 and 17% moisture content (m.c, wet base). Two correlations were used for smoothing gas concentration in time: linear and exponential. Then, the respiration rate at each temperature and m.c. combination was calculated as storage time progressed and oxygen was consumed and two predictive models for respiration were proposed: Model I (temperature and m.c. dependent) and Model II (temperature, m.c. and oxygen dependent). It was observed that respiration rate increased with storage m.c. and temperature. However, respiration rate was not mainly affected by O2 until a critical concentration limit of about 2% was reached. Respiration rates were from 0.341 to 22.684 mg O2\/(kgDM d) and from 0.130 to 20.272 mg CO2\/(kgDM d) for a range of storage condition of 13-17% m.c. and 15-35°C temperature. The respiration rate of soybean seeds obtained in this study resulted significantly lower than the rates reported in the literature for other grains at similar temperature and aw (water activity) storage condition.  For hermetic storage simulations in which O2 concentration is not expected to drop below 2%, the simplest model (Model I) could be used, but if the O2 concentration of the hermetic system is expected to be depleted, Model I would under estimate the time at which O2 is consumed, and thus a model with O2 dependency is recommended instead (Model II).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240052,"idioma_id":4,"titulo":"Impaired ovarian response to exogenous gonadotropins in female rat offspring born to mothers perinatally exposed to Bisphenol A","resumen":"The ovary is sensitive to disruption by the environmental estrogen Bisphenol A (BPA). Our aim was to investigate whether perinatal exposure to BPA (50 µg\/kg.day), orally administered, affects ovarian response to exogenous gonadotrophins (PMSG or PMSG+hCG) in prepubertal female offspring. An altered response to gonadotrophins was observed in BPA-exposed rats. Increased proportion of antral follicles, altered levels of ovarian steroidogenic enzymes, gonadotropin receptors, AR and ER&#946; were observed in PMSG group. Besides that, in response to PMSG+hCG, a persistent high Fshr mRNA expression and a decreased number of follicles with high expression of PR before ovulation were observed. After ovulation, there was an increase in antral atretic follicles, reduced Lhcgr mRNA expression and high serum levels of E2. Therefore, an early exposure to a low dose of BPA during perinatal period induces ovarian changes leading to an altered response to exogenous gonadotropin treatment later in life.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240055,"idioma_id":5,"titulo":"Aplicación del modelo de revaluación de la RT 31. Su incidencia en la medición del patrimonio y los resultados","resumen":"La incorporación del modelo de revaluación en la RT 17 ha permitido lograr una armonización con las NIIF en materia de medición de los bienes de uso, atento que la NIC 16 lo admite como alternativa. La elección entre el modelo de costo y el modelo de revaluación tendrá, en la mayoría de los casos, un impacto significativo en la medición del patrimonio y los resultados. Así, contabilizar un incremento en la medición de los bienes de uso permitirá mostrar una mejor situación patrimonial, pero traerá aparejado el cómputo de mayores amortizaciones en los ejercicios futuros y, por ende, menores ganancias o mayores pérdidas. El modelo de costo se presenta como la opción más sencilla y menos costosa. No obstante, es indudable que la utilización de valores razonables permite arribar a mediciones contables más cercanas a la realidad económica, por lo que es superior al de costo en cuanto al cumplimiento de los requisitos que debe reunir la información contable.El modelo de revaluación descripto en la RT 31 plantea criterios alternativos referidos al tratamiento del saldo por revaluación, permite optar por mantenerlo o transferirlo a resultados no asignados ya sea por retiro, disposición o consumo de los bienes revaluados que le dieron origen. La posibilidad de distribuir o capitalizar el saldo por revaluación surge a partir de su desafectación mediante su transferencia a resultados no asignados. Por lo tanto la alternativa que se seleccione para el tratamiento del saldo por revaluación tendrá efecto en el importe de los resultados capitalizables o distribuibles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240056,"idioma_id":4,"titulo":"Resistance of phages lytic to pathogenic Escherichia coli to sanitisers used by the food industry and in home settings","resumen":"Phages are potentially useful as antimicrobial agents in food-processing environments, provided they can remain active upon extended storage and in the presence of sanitisers. Survival of six phages lytic againstenteropathogenic (EPEC) and shiga-toxigenic (STEC) Escherichia coli strains was assessed upon storage at 4 °C, 20 °C and 70 °C in phosphate-buffered-saline (PBS) and Tris-magnesium-gelatine buffer (TMG) for up to 1 year. The phages were also exposed to ethanol, sodium hypochlorite, peracetic acid, quaternary ammonium chloride (biocide A), hydrogen peroxide\/peracetic acid\/peroctanoic acid (biocide B), p-toluensulfonchloroamide (biocide D) and alkaline chloride foam (biocide C). Plaque-forming units remained unchanged when the phages were stored at 4 °C in both buffers tested, but decreased by 3.5 and 5.7 log10 PFU when stored in PBS at 20 and 70 °C, respectively. Moreover, TMG seems to be the most protective suspension medium with decreasing temperature because a 1log10 PFU reduction was observed at 20 and 70 °C. Incubation in 100% ethanol for 24 h reduced plaque counts only by 2.5 log10 PFU. In 10 ppm of sodium hypochlorite and in biocide B (0.13%), the counts decreased by ~5 and ~6 log10 PFU after15 min. Finally, biocide A and D reduced counts by 4 and 2?4 log10 PFU after 30 min and 8 h of incubation, respectively. Phages were completely inactivated only by peracetic acid and biocides C and E. Therefore, the phages evaluated might be potentially applied together with classical sanitisers such as ethanol andindustrial biocides A, B and D, in disinfection programs against pathogenic STEC and EPEC strains.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240057,"idioma_id":4,"titulo":"Study of dielectric strength in EPDM by nondestructive dynamic mechanical analysis in high electrical field","resumen":"In the present work the value of the degree of the area swept by the polymer chain due to an electrical force for a given mesostructure was related to the corresponding value of the dielectric strength. This value was deduced from the electric inclusion formalism applied to dynamic mechanical analysis (DMA) studies conducted under high electric field, which were performed in commercial ethylene-propylene-diene M-class rubber (EPDM); used for the housing of polymeric electrical insulators. EPDM samples with different arrangements of the polymer chains and crystalline degree, promoted by controlled neutron irradiation were studied. Several characterization techniques, as infrared absorption spectroscopy (IR), differential scanning calorimetry (DSC), positron annihilation lifetime spectroscopy (PALS) and dielectric strength (DS) were also used. The relationship between the DS and the degree of movement of polymer chains promoted by electrical forces coming from the electric field applied in a non destructive test as the DMA was successfully established. In fact, a larger empty space in the sample leads to larger areas swept by the polymer chains during bending under the application of the field strength in the dynamic mechanical analysis tests.Therefore, an increase in the capability of movement of charges occurs, corresponding to smaller dielectric strength values. Crystallinity improves the dielectric strength due to the increase in the internal stresses which decreases the capability of movement of the polymer chains and electric carriers by electric forces.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240058,"idioma_id":5,"titulo":"Escenario actual de la normativa contable en Argentina. Opciones para entes pequeños y medianos.","resumen":"Bajo el marco normativo actual un mismo ente (exceptuando los que estén obligados a aplicar la RT 26) puede utilizar distintos juegos de normas. Si analizamos puntualmente el caso de un EP, y suponemos que este tipo de empresas aplicará las Normas profesionales argentinas, nos encontramos con que, a su vez, pueden optar por aplicar tres normas contables distintas (RT 41, RT 42 y RT 17) para medir sus activos y pasivos. Entonces, cabe la pregunta ¿Qué quedó de la comparabilidad? ¿Qué quedó de aquel atributo de la información contable definido en el Marco Conceptual de las normas argentinas? Porque según se desprende del texto de esa norma, los usuarios deben poder realizar la comparación de la información contenida en los estados contables desde dos puntos de vista diferentes: una ?comparación hacia adentro? (del mismo ente a la misma fecha o período o del mismo ente a otras fechas o períodos) y una ?comparación hacia afuera? (de otros entes). En el caso de que la empresa aplicara uniformemente, año tras año, el mismo juego de normas contables y las mismas alternativas pareciera que no hay inconvenientes para obtener información comparable dentro de la misma empresa. Pero, sin lugar a dudas, lo que se ha perdido es la posibilidad de realizar la comparación con la información contable de otras empresas. Consideramos que es necesario que las normas vigentes se ajusten a la realidad de las empresas, por lo que celebramos la aprobación de normas específicas para Entes pequeños y Entes medianos. Sin embargo, no se puede soslayar que la incorporación de un variado abanico de posibilidades dentro de una misma norma, tal el caso de la RT 41, para medir los créditos en moneda, las deudas en moneda, los bienes de cambio y el costo de ventas atenta contra el atributo mencionado. Como consecuencia de ello, podría presentarse la situación de que dos empresas que apliquen la misma norma contable a las mismas operaciones puedan presentar activos, pasivos y resultados totalmente distintos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240059,"idioma_id":4,"titulo":"Contributions of ecological facilitation for restoring environments with high conservation value in the Argentine Patagonia","resumen":"The Argentine arid Patagonia, in general, and ?La Payunia?ecosystem in particular, are important areas for conservationdue to the high number of endemic species. However, this regionpresents a high level of degradation as a result of human activities.Thus, ecological rehabilitation strategies need to be implemented torecover certain areas. The main objectives of this study were to (1)evaluate the reintroduction of two selected native species in severelydegraded areas, and (2) determine if the survival and growth of anendemic shrub species, Senna arnottiana, increase when it is associatedwith a perennial grass, Pappostipa speciosa. These two species wereselected based on the results of a reference ecosystem analysis. In addition,two doses of hydrogel (polyacrylamide) were tested to evaluateits moistening effect. After three years, the survival rate of bothplant species was high (mean=79.6%), with no significant differencesamong hydrogel treatments and association between species. However,growth rates of S. arnottiana plants nursed by P. speciosa weresignificantly higher (P<0.05) than those of isolated plants. Our resultssuggest that the study, endemic shrub species is able to survivein isolation after its transplanting, and that P. speciosa is a suitablespecies for promoting a higher shrub growth during the first criticalyears of recovery of the degraded, arid and semiarid environments","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240060,"idioma_id":4,"titulo":"Prevention of intestinal parasites in a tri-border area of Latin America: Children perceptions and an integral health education strategy","resumen":"To investigate knowledge of school-aged children and their perception on intestinal parasites, and to assess knowledge reconstruction on prevention practices after specific training in the subject. We performed an activity package that included the analysis of children´s drawings of intestinal parasites, and information and communication technologies (ITCs) to transfer knowledge about these pathogens and prevention measures. Retrieval learning activities were performed to fixation of general and specific prevention and control measures.Overall, we found that there is a knowledge gap in many aspects of parasite biology and ecology, and therefore on the risk of infection and acquisition mechanisms. After ITCs, the children improved their knowledge over non-trained children.The approaches used to transfer knowledge and for learning, fixation were valuable tools for incorporating changes in misconceptions and in the deep-rooted habits that favour entero-parasitic diseases. This has important implications for the specific design of future education materials and campaigns. Understanding of perceptions helps to provide justifications and knowledge to achieve changes in unhealthy habits, and it constitutes the basis for the transformation of many risky practices.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240061,"idioma_id":4,"titulo":"Leaf venation pattern to recognize austral South American medicinal species of cow's hoof (Bauhinia L., Fabaceae)","resumen":"The leaves extracts of some species of Bauhinia L. s.l. are consumed to treatdiabetes, inflammation, pains and several disorders in traditional medicine in austral South America. Despite its wide use andcommercialization, sale is not controlled, and botanical quality of samples isnot always adequate because of plant misidentification and adulteration. Here,we characterized leaf vein pattern in nineteen taxa to contribute to the recognitionand commercial quality control of plant material commerciallyavailable. The veincharacters intercostal tertiary and quinternary vein fabric, areole developmentand shape, free ending veinlet branching and marginal ultimate venation allowedto distinguish the main medicinal species in the region. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240062,"idioma_id":5,"titulo":"Cuando los movimientos llegan a la oficina. Dilemas del Movimiento Evita en un gobierno municipal de Buenos Aires, Argentina (2004-2015).","resumen":"En la presente investigación se analiza el caso del Movimiento Evita, un movimientosocial contemporáneo de Argentina conformado en 2004, en relación con suocupación y con la gestión en un gobierno municipal de la provincia de Buenos Aires.Este análisis se realiza desde la observación del ?dilema? planteado en la literaturaacadémica acerca de los límites y las potencialidades de la integración al Estado porparte de los movimientos sociales. Para ello se atiende al caso del Movimiento Evitaen el municipio de Avellaneda, donde tras un ciclo de acumulación políticaexclusivamente barrial y con fuerte asiento en las dinámicas de poder instituyente ycombativo, el movimiento fue integrando a sus militantes a la estructura de gobiernomunicipal, a partir de su adhesión a los gobiernos presidenciales de Néstor Kirchner yde Cristina Fernández, que se desplegaron en Argentina entre 2003 y 2015. En esteestudio, se focaliza en las relaciones que el movimiento construyó por fuera y pordentro de la institucionalidad estatal en dicho municipio del conurbano sur de laprovincia de Buenos Aires, y en los límites y potencialidades que dicha intervencióngeneró en su construcción cotidiana.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240063,"idioma_id":5,"titulo":"Del antipatriarcado al feminismo: derivas del ethos militante en un movimiento social de la Argentina (2004-2015)","resumen":"El presente artículo se ocupa de observar el recorrido de la cuestión de género en un movimiento social contemporáneo en Argentina, a partir de las tendencias prefigurativas o pragmáticas que muestran los ethos militantes. Se trabajó para ello con entrevistas en profundidad, observaciones de campo y análisis de los documentos producidos por el Frente Popular Darío Santillán (FPDS). Los resultados de este trabajo permiten corroborar la presencia de un ethos prefigurativo relativo a la cuestión de género en este movimiento, al tiempo que ayudan a relativizar las divisiones tajantes entre los 'viejos' y los 'nuevos' modelos de militancia, encontrando continuidades y rupturas entre ellos. Estos resultados se enmarcan en las conclusiones generales de mi estudio de maestría del año 2013","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240064,"idioma_id":5,"titulo":"¿Existen las generaciones políticas? Reflexiones en torno a una controversia conceptual","resumen":"Laconceptualización y aplicación de la noción de ?generación? ha sido objeto de múltiples debates en el campode la teoría social contemporánea. En el presente texto, se presenta el recorrido que tuvo la utilización delconcepto en el campo de la teoría social, desde sus primeras aplicaciones hastalos enfoques contemporáneos. A su vez, se da cuenta de las principales impugnacionesactuales a la utilización de esta noción, para sustentarfinalmente un posicionamientopropio respecto al debate, que rescata la pertinencia delconcepto de generación política para la comprensión de las dinámicas de losmovimientos sociales, en función de una perspectiva amplia y comprensiva.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240065,"idioma_id":5,"titulo":"La etapa kirchnerista. Nuevo 'momento constitutivo' entre movimientos sociales y Estado en Argentina.","resumen":"El presente trabajo analizalas relaciones entre movimientos sociales, Estado y gobierno, desde la ópticateórica propuesta por René Zavaleta, a partir de sus conceptos de 'forma primordial' y de 'momento constitutivo'. A partir de un trabajo de campo conobservación y entrevistas en profundidad con dos movimientos sociales dematrices político ideológicas autonomista y nacional-popular, el resultado delanálisis confirma la profunda reformulación en las relaciones entre movimientossociales y Estado que tuvo lugar desde la relegitimación institucional, acontecida en el marco de los gobiernos de Néstor Kirchner y de CristinaFernández de Kirchner entre 2003 y 2015 en el país.El artículo concluyeentonces que, allende la inscripción político-ideológica de los movimientos sociales, la etapa kirchnerista se constituyó como un nuevo 'momento constitutivo' en la relación entre el Estado y los movimientos sociales,modificando aspectos estratégicos y tácticos de los vinculamientos en éstos respectode la esfera institucional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240079,"idioma_id":5,"titulo":"Los derroteros de un genio melancólico","resumen":"Este artículo ofrece una discusión en torno a la configuración de la imagen de autor de Fernando Vallejo. Me referiré específicamente a la autoficción La virgen de los sicarios para definir y poner en cuestión, en primer lugar, el término autoficción; y para dar cuenta de los procesos de autofiguración que el colombiano utiliza en la literatura y en el cine en tanto formas que delinean la construcción de un personaje peculiar -un genio melancólico- de la literatura latinoamericana actual.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240080,"idioma_id":5,"titulo":"Fernando Vallejo biógrafo. La vida de los otros y la potencia de la autofiguración,","resumen":"En este trabajo, me interesa resaltar la obra biográfica de Fernando Vallejo  (El mensajero, Almas en pena chapolas negras, y El cuervo blanco) para dar cuenta de las modulaciones de lo autobiográfico en la narrativa de un mismo autor. Cuando un escritor decide contar el pasado íntimo de otro escritor se ponen en juego ciertos procesos que ponen en evidencia no sólo el carácter ambiguo inherente al propio género biográfico sino también la tensión entre la idea de una vida como proceso y la biografía como convención. Al mismo tiempo, la figura del autor-narrador se tensiona entre el biógrafo profesional y el escritor movido por el deseo de indagar en otro escritor. Por esto, sería enriquecedor poner en paralelo lo que hace Vallejo consigo mismo en las autoficciones y lo que hace con la vida de los otros en las biografías.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240081,"idioma_id":5,"titulo":"El problema del nombre. Los casos de Julián Herbert y Jorge Baron Biza","resumen":"Dos relatos sobre el dolor ajeno. Dos madres convalecientes en una cama de hospital, dos hijos sentados en el sillón contiguo a esa cama. Dos hijos que escriben en primera persona para intentar escaparle al dolor con la simple diferencia que uno usa su nombre para hacerlo y el otro elige modificarlo. Me interesa leer juntos El desierto y su semilla de Jorge Baron Biza y Canción de tumba de Julián Herbert para indagar en el problema del nombre propio. En el análisis sobre la ambigüedad entre autobiografía y novela que revelan ambas autoficciones, quisiera problematizar sobre la elección del nombre para poder primero establecer la operatividad del término autoficción; y segundo, señalar, en cada caso, la singularidad de la voz narrativa a través de la técnica que pone en tensión los mecanismos de recuerdo y memoria. El artículo está incluido en el Dossier 'Autoficción y Escrituras del yo'","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240084,"idioma_id":4,"titulo":"Thymol feed supplementation in quail alters the percentages of nutritionally relevant egg yolk fatty acids: effects throughout incubation","resumen":"BACKGROUND: PUFA are crucialcomponents of the yolk and particularly prone to oxidative damage generatinglosses of nutrients for embryonic development and influencing the quality ofeggs for human consumption. We evaluated whether dietary thymol (a naturalantioxidant) is related to changes in quail egg yolk total, triglycerides andphospholipids fatty acid composition (T, TG, PL, respectively) at differentstages of embryo development. Thus, female Japanese quail (100d) were assignedto 1 of 2 dietary treatments (12 individuals each): CON (basal diet) or THY(0.042mol of thymol kg of basal diet-1). After 2 weeks ofsupplementation, eggs were incubated and samples were obtained at 0, 4 and 16dof embryonic development.RESULTS: In 0d-THY-eggs,alpha-linolenic acid and n-3 PUFA in T and TG, docosahexaenoic acid and PUFA inT, and arachidonic acid in TG were increased, while SFA in T was reduced. From4d on, PUFA, n-3 PUFA and SFA from T and TG in THY-eggs, were found similar toCON-eggs. The changes in PL throughout incubation were similar in both dietarytreatments.CONCLUSION: Thymol would providethe embryo with PUFA for synthesis\/deposition in membranes and\/or derive tosupply energy. Additionally, thymol supplementation would be advisable for theproduction of healthier table-eggs.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240086,"idioma_id":4,"titulo":"Unexpected results when assessing underlying aggressiveness in Japanese quail using photocastrated stimulus birds","resumen":"Aggressive behaviors can affect both animalwelfare and productivity. Because the expression of aggressive behaviors isdependent on the quality of the opponent, they reflect relative rather thanabsolute levels of underlying aggressiveness. This study was aimed to characterize the aggressive responsiveness ofphotostimulated (14:10h light:dark photoperiod) adult Japanese quail wheninteracting with a photocastrated (6:18h light:dark photoperiod) counterpart ina novel test environment and to assesses interindividual variations. This was based on theassumption that photocastrated birds will not actively provoke an aggressiveconfrontation. Birds were reared in male-female pairs. Frequencies of behaviors(i.e., pecks, threats, chases, grabs, mounts) were determined during 10 minsocial interactions in a novel environment. A first experiment evaluated 78encounters between a photostimulated male or female with either aphotocastrated male or female (photocastration of sexually mature birds startedat 11 wk of age). High interindividual variability was observed and in general,highly aggressive birds (performing 20or more aggressive interactions) received little or no aggression from their testcounterpart. However, unexpectedly, we also found that 37 and 32% ofphotocastrated males and females, respectively, performed aggressions towardtheir photostimulated counterparts, and initiated the aggressive interactionsin a similar proportion than photostimulated males. Aggressive photocastratedmales did not perform reproductive-type behaviors (i.e. grabs, mounts). Aggressivenessin the photocastrated birds was attributed to their social experience prior tophotocastration. Therefore, a second experiment evaluated 106 encounters betweena photostimulated male or female and a naive photocastrated male(photocastration started at 4 wk of age, prior to sexual development). Photocastratedmales performed no aggressions toward their photostimulated counterparts.Consistently with previous studies, our findings show that naive photocastratedmales can be used as a non-aggressive stimulus during a social interactionaimed to assess expression of aggressiveness in photostimulated birds. However,caution should be taken when applying the photocastration protocol consideringthat prior fighting and sexual experience or other physiological changesrelated with maturation can interfere during subsequent aggressive testing.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240087,"idioma_id":5,"titulo":"Dispositivos modales para la construcción interactiva de la identidad en el coloquio de la defensa de tesis doctoral","resumen":"El discurso es un sistema de representación donde se construyen las identidades de los participantes mediante distintos dispositivos modales (Fontanille 2001). Este trabajo parte del supuesto de que las funciones discursivas del coloquio de tesis doctoral se basan en la noción de ?doctorancia? (doctorateness, Trafford y Leshem 2008) y se propone indagar cómo se construye la identidad del tesista y de los jurados, poniendo en relación las funciones del discurso con las modalidades de la enunciación. Se realiza un análisis cualitativo, descriptivo y explicativo de fragmentos de tres defensas doctorales de distintas disciplinas, transcriptas siguiendo el sistema Val.Es.Co. Los resultados sugieren que, como en toda comunicación donde el objeto de valoración es el saber, en el coloquio de la defensa de tesis doctoral las identidades se construirían básicamente sobre modalizaciones epistémicas, aunque también formarían parte de la estructura modal fundamental del discurso las modalidades éticas del compromiso y la competencia, tanto desde una perspectiva endotáctica como exotáctica. Finalmente, terminarían de cerrar el entramado modal del coloquio de la defensa doctoral las modalidades volitivas y las cognoscitivas del conocimiento y de la ignorancia, que aportarían al discurso distintos matices de significación, fundamentalmente relacionados con el sistema pragmático de cortesía verbal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240088,"idioma_id":4,"titulo":"Industrial Plant at Academic Level for Teaching Industrial Informatics in an Electronic Engineering Undergraduate Degree","resumen":"Abstract: This paper presents the design of an academic level simulation for an industrial plant and the current status of prac-tice activities proposed for an undergraduate course on industrial automation for electronic engineering students. Strongly focused on professional processes and methods, in particular, it deals with the specific activities developed by electronic engineers at the lower levels of the automation pyramid.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240089,"idioma_id":5,"titulo":"UN ESTUDIO SOBRE LAS CONCEPTUALIZACIONES DE ESTUDIANTES ACERCA DE CONCEPTOS BÁSICOS INVOLUCRADOS EN LA ECUACIÓN DE ONDAS MECÁNICAS Y SU TRATAMIENTO EN LIBROS DE FÍSICA","resumen":"Trabajo enviado para su evaluaciónEn el ciclo inicial universitario, formandoparte de los contenidos de mecánica, se aborda el estudio de las ondas &nbsp;mecánicas transversales representándolasmatemáticamente a través de una función armónica de dos variables que involucraparámetros característicos cuya naturaleza no es inmediata para los estudiantes.Se presenta un estudio sobre los aprendizajes logrados por parte de estudiantesque cursan carreras científico-tecnológicas, acerca de los significadosatribuidos a la amplitud, frecuencia, rapidez de propagación, longitud de onday fase inicial en dicha ecuación. Por otro lado, se indagó sobre el tratamientoque se da a estos parámetros en libros de física usados frecuentemente en elciclo inicial; se investigó si se explica adecuadamente el origen físico de losmismos. Del estudio realizado se desprende, por un lado, que los estudiantes presentandificultades en comprender la naturaleza de las magnitudes y parámetrosinvolucrados - amplitud, frecuencia, rapidez de propagación y longitud de onda-,y el significado físico de la constante de fase; y por otro, que no todos losautores de los libros de mecánica analizados hacen referencia de un modoexplícito, y con los detalles convenientes alrededor de los mismos. Semencionan recomendaciones a los docentes para el diseño de estrategiasdidácticas que favorezcan la comprensión del fenómeno ondulatorio y supropagación en los estudiantes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240090,"idioma_id":5,"titulo":"LA COMPLEJIDAD DE LAS SIMPLIFICACIONES EN LA ENSEÑANZA DE LA MECÁNICA EN EL CICLO INICIAL UNIVERSITARIO: EL CASO DEL TRATAMIENTO DE LAS POLEAS EN LIBROS DE TEXTO","resumen":"Se presenta un estudio sobre libros de texto de Mecánica de uso generalizado en cursos de Física del ciclo inicial universitario de carreras científico tecnológicas dictadas en universidades de habla hispana. A través de un análisis de contenido se investigó por un lado, sobre las explicaciones dadas por los autores de los libros acerca de las hipótesis ?simplificadoras? que se adoptan para abordar el estudio del comportamiento de las poleas en los temas iniciales de Mecánica, consistentes en considerarlas de masa despreciable y sin rozamiento; y por otro, si esas hipótesis son retomadas en el estudio de Sólidos en rotación. Se sostiene que si bien en la enseñanza se introducen hipótesis simplificadoras que facilitarían la comprensión de los fenómenos físicos por parte de los estudiantes, éstas no siempre resultan claras a los mismos, conllevando a obstaculizar, más que simplificar, la conceptualización aplicada al comportamiento de sistemas físicos cuando estudian a partir de libros de texto. Se advierten cuestiones que resultarían provechosas para los docentes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240091,"idioma_id":5,"titulo":"LA MODELIZACIÓN DE RESORTES CON MASA DESPRECIABLE: DIFICULTADES DE LOS ESTUDIANTES EN SU CONCEPTUALIZACIÓN Y SU TRATAMIENTO EN LIBROS DE FÍSICA USADOS EN EL CICLO INICIAL UNIVERSITARIO","resumen":"En la enseñanza de la Física, al abordar los temas de Mecánica, son numerosas las situaciones tratadas que involucran masas vinculadas a través de resortes en las que, con fines simplificadores, se idealizan a los resortes asignándoles masa despreciable. Se presenta un estudio sobre las conceptualizaciones, desde los puntos de vista dinámico y energético, logradas por estudiantes universitarios que cursan carreras científico-tecnológicas, acerca de dichamodelización. A partir de resultados obtenidos con relación a las conceptualizaciones, se indagó sobre el tratamiento que de esta idealización presentan los libros de texto de física usados frecuentemente en el ciclo inicial. En estos últimos se investigó, si se explican adecuadamente lasconsecuencias físicas derivadas de considerar a los resortes sin masa. Del estudio realizado se desprende, por un lado, que no es inmediato para los estudiantes establecer nexos entre esta modelización, y la aplicación de las leyes y principios físicos, al abordar situaciones problemáticas; y por otro, que no todos los autores de los libros de Mecánica frecuentemente utilizados presentan análisis detallados acerca de la misma. Se destacan recomendaciones para ser consideradas por docentes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240093,"idioma_id":4,"titulo":"Application of inter-simple sequence repeat markers in the analysis of populations of the Chagas disease vector Triatoma infestans (Hemiptera, Reduviidae)","resumen":"Here we apply inter-simple sequence repeat (ISSR) markers to explore the fine-scale genetic structure and dispersal in populations of Triatoma infestans. Five selected primers from 30 primers were used to amplify ISSRs by polymerase chain reaction. A total of 90 polymorphic bands were detected across 134 individuals captured from 11 peridomestic sites from the locality of San Martín (Capayán Department, Catamarca Province, Argentina). Significant levels of genetic differentiation suggest limited gene flow among sampling sites. Spatial autocorrelation analysis confirms that dispersal occurs on the scale of &#8764;469 m, suggesting that insecticide spraying should be extended at least within a radius of &#8764;500 m around the infested area. Moreover, Bayesian clustering algorithms indicated genetic exchange among different sites analyzed, supporting the hypothesis of an important role of peridomestic structures in the process of reinfestation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240095,"idioma_id":5,"titulo":"Detecci&oacute;n serol&oacute;gica de Brucella suis , virus de influenza y virus de la enfermedad de Aujeszky en criaderos porcinos familiares de menos de 100 madres en Argentina","resumen":"Los criaderos porcinos de menos de 100 madres representan más del 99% de los detodo el país; sin embargo, existen escasos reportes sobre su situación sanitaria y productiva.Se recabó información productiva y se tomaron muestras para detectar anticuerpos contraBrucella suis (Bs), virus de la enfermedad de Aujeszky (VA) y virus de influenza (VI) en68 establecimientos de menos de 100 madres ubicados en la región norte, centro y sur delpaís.El 80% de los establecimientos fueron positivos al VI H1 pandémico 2009, el 11% al H3 clúster2, mientras que el 11,7% presentó anticuerpos contra el VA y el 6% contra Bs.Ninguno de los productores conocía los factores de riesgo para la transmisión de enfermedadesdel cerdo al humano. El 47% compra sus reproductores a pares o en ferias. En lo que respectaa normas de bioseguridad, solo el 16% de los establecimientos tenía cerco perimetral y el 37%de las granjas contaba con asesoramiento veterinario.Los resultados de este estudio demuestran que la caracterización productiva y el relevamientosanitario son de suma importancia para mejorar la productividad y reducir el riesgo de transmisión de enfermedades. El conocimiento de la situación sanitaria y de los factores deriesgo es necesario para conseguir un mejor control y la erradicación de enfermedades ensistemas de baja tecnificación. Se deberían llevar a cabo estudios más representativos a nivelpaís para detectar los agentes circulantes y, sobre la base de esta información, implementarmedidas de prevención y control.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240096,"idioma_id":5,"titulo":"-\tEl docente y el clima escolar","resumen":"Cuando entramos a una escuela, percibimos el ambiente queen ella circula con solo mirar, escuchar y hablar. Existen dos tipos declimas: los que invitan a trabajar con tranquilidad, donde el aprendizaje, elcompartir, la confianza y el compromiso están presentes y cimientan bienestar, ylos climas tensos, cargados de silencios, desconfianzas, aislamientos, rumores,incomunicación y quejas, donde se exterioriza el malestar. Nuestros estadosemocionales se contagian cuando compartimos la alegría, el miedo, el humor, laangustia, la tristeza, la ira, la preocupación, el resentimiento, laresignación y la frustración, entre otros. Nos tocan y condicionan no solo ennuestro accionar, sino también, en el de quienes nos rodean, al extremo de &nbsp;impactar en la salud física y mental de todos losque interactúan.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240097,"idioma_id":4,"titulo":"Variation in density, size, and morphology of the pulmonate limpet Siphonaria lessonii along the Southwestern Atlantic","resumen":"The density, size, and morphology of coastal invertebrate species often predictably vary with latitude. In thisstudy we evaluate whether the density, size, and morphology of the pulmonate limpet, Siphonaria lessonii, in theSouthwestern Atlantic varies in agreement to the predictions of the abundance-centre hypothesis (i.e., higherdensities by the center of the species range), Bergmann´s rule (i.e., increasing body size with latitude), and Allen´srule (i.e., decreasing body surface to volume ratio with latitude). Our results indicate that the upper densitybounds of S. lessonii decrease with latitude across our study range, which may either contradict expectations ofthe abundant-centre model (i.e, if assuming a Temperate Southwestern Atlantic\/Magellanic distribution; 27°S inthe Atlantic to 42°S in the Pacific) or represent a partial trend within a broader scale, abundant-centre pattern(i.e., when considering a panmictic distribution from the Temperate Southwestern Atlantic to the TemperateSoutheastern Pacific; 27°S in the Atlantic to 5°S in the Pacific). Limpet shell length (i.e., a surrogate of body size)was not significantly related to latitude (cf. Bergmann´s rule). The two principal components of morphologicalvariation in limpet shells ? which increased with decreasing shell surface to volume ratio ? showed positive andnegative relationships with latitude (i.e., contradictory support to Allen´s rule). From these analyses, we conclude(a) that the size and morphology of S. lessonii are primarily controlled by local conditions rather thanbroad-scale climatic or environmental gradients and, (b) that geographic marginality does not means reducedperformance in this species at least as it concerns to abundance and maximum size.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240098,"idioma_id":5,"titulo":"Dátiles de mar: mejillones que perforan las rocas costeras","resumen":"A diferencia de sus famosos homónimos producidos por palmeras, los dátiles de mar son animales. Se trata de unos moluscos bivalvos poco conocidos que miden unos pocos centímetros y se distinguen por su capacidad de horadar cavidades en rocas calizas de la zona intermareal. Viven en ellas protegidos de predadores, del embate de olas y de la desecación que los amenaza cuando se retiran las aguas. No perforan las rocas en forma mecánica sino química, pues secretan un ácido que disuelve el carbonato de calcio. Su acción hace que a menudo se los considere perjudiciales, aunque también contribuyen al incremento de la biodiversidad del ambiente costero. Una especie de ellos, llamada Lithophaga patagonica, es muy abundante en las costas argentinas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240099,"idioma_id":5,"titulo":"Democratización universitaria, de la expansión al contexto actual","resumen":"El proceso de expansión universitaria en nuestro país atravesó, desde su inicio hasta nuestros días, diversas etapas, que caracterizamos como ?oleadas expansivas? y que tuvieron distintos sentidos y muy diversos objetivos. La primera de ellas, asociada con el ?Plan Taquini?, tuvo como fin la desconcentración de los grandes núcleos estudiantiles que resultaban problemáticos para el régimen militar. De este modo, entre los años 1971 y 1973 se crearon trece instituciones educativas y tres más hasta 1980. La segunda etapa expansiva del sistema se produjo durante la década de los noventa y se concentró principalmente en la Provincia de Buenos Aires, donde se emplazaron seis de las nueve universidades fundadas durante el período. Esta etapa estuvo fuertemente marcada por el impacto de las recomendaciones de los organismos multilaterales de crédito, cuya influencia logró la cristalización normativa de una lógica mercantilista en la educación superior con la sanción de la Ley de Educación Superior (Nº 24.521). Finalmente, a partir del año 2003, asistimos a una nueva ola expansiva del sistema universitario de gestión pública que se manifestó con la creación, durante los tres períodos de gobierno del kirchnerismo, de veintitrés universidades nacionales e institutos universitarios nacionales a lo largo y a lo ancho del país.Este último capítulo de este proceso de expansión, creemos, tiene como contexto un proceso político que concibió a la ampliación de derechos como una estrategia fundamental para la reconstrucción de la vida democrática en nuestro país. Dicho de otro modo, uno de los rasgos principales de esta expansión es que se llevó adelante de la mano de un discurso sobre la ?democratización? de la Universidad presente fundamentalmente en las razones declaradas por los actores políticos que impulsaron la creación de las nuevas universidades en todo el país y que se plasmó también en los diversos documentos fundacionales de estas instituciones. Este discurso motivó también la formulación de otras políticas en el contexto universitario, y por dicho motivo creemos que caracterizó en general a las políticas públicas de los gobiernos kirchneristas relacionadas con la educación universitaria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240103,"idioma_id":4,"titulo":"Regional climate of the Larsen B embayment 1980&ndash;2014","resumen":"Understanding the climate response of the Antarctic Peninsula ice sheet is vital for accurate predictions of sea-level rise. However, since climate models are typically too coarse to capture spatial variability in local scale meteorological processes, our ability to study specific sectors has been limited by the local fidelity of such models and the (often sparse) availability of observations. We show that a high-resolution (5.5 km × 5.5 km) version of a regional climate model (RACMO2.3) can reproduce observed interannual variability in the Larsen B embayment sufficiently to enable its use in investigating long-term changes in this sector. Using the model, together with automatic weatherstation data, we confirm previous findings that the year of the Larsen B ice shelf collapse (2001\/02) was a strong melt year, but discover that total annual melt production was in fact &#8764;30% lower than 2 years prior. While the year before collapse exhibited the lowest melting and highest snowfall during 1980?2014, the ice shelf was likely pre-conditioned for collapse by a series of strong melt years in the 1990s. Melt energy has since returned to pre-1990s levels, which likely explains the lack of further significant collapse in the region (e.g. of SCAR Inlet).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240106,"idioma_id":5,"titulo":"Descortezado en forestales producido por la ardilla introducida Callosciurus erythraeus (Sciuridae) en Argentina","resumen":"En este trabajo se describe el daño ocasionado en diferentes árboles por un mamífero exótico introducido en Argentina, la ardillade vientre rojo (Callosciurus erythraeus), en el principal foco de invasión del país. Se trabajó en cuatro lugares forestados, dondese registraron las especies dañadas, el tipo e intensidad del daño, en 38 parcelas de entre 150 y 250 m2. Las ardillas afectaron unagran cantidad de individuos y especies forestales, varias de ellas de importancia comercial. En 12 especies se registraron árbolescon elevados niveles de daño observándose que en promedio el 57 % de los individuos presentó heridas por debajo de los 5 m.Los resultados revelaron que la ardilla de vientre rojo resulta una especie perjudicial en su área de influencia para muchas especiesforestales y puede ser una amenaza para otras regiones forestales del país si continúa expandiéndose; se discuten las implicancias desu impacto en términos de la producción forestal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240107,"idioma_id":4,"titulo":"Effect of botanical and physicochemical composition of Argentinean honeys on the inhibitory action against food pathogens","resumen":"Honey is a natural food with functional properties such as antioxidant and antimicrobial activities. These properties vary greatly depending on floral source, climate, and environmental and processing conditions. In this work, we characterized honeys on the basis of their botanical composition and clustered them according to their physicochemical parameters in order to find similarities, and assess their antibacterial action against microorganisms isolated from contaminated food. All honeys studied complied with international quality standards. The data showed differences between multifloral and unifloral honeys in their physicochemical parameters, as well as a direct correlation between colour, phenolic compounds, and antioxidant activity. -Antimicrobial activity resulted from hydrogen peroxide effect. Multifloral honeys with similar phenolic compounds and a botanical composition of eucalyptus and blueweed had greater inhibitory power against E. coli, P. aeruginosa, Salmonella spp., S. aureus and B. cereus.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240109,"idioma_id":5,"titulo":"Sobre el concepto de ciudadanía desde una mirada comunicacional","resumen":"Desde la recuperación de la democracia, elconcepto de ciudadanía ha adquirido vigenciaen los estudios de los diferentes camposdisciplinares de las Ciencias sociales. Si bienestas perspectivas abordan al ciudadanocomo un sujeto de derecho, las mismas noindagan en la construcción del imaginariosocial y las prácticas socio históricas que vantransformando los sentidos, saberes y lasformas de intervención y\/o incidencia de losciudadanos en las políticas públicas denuestro país. Debido a ello, este artículopretende estudiar el término de ciudadaníadesde una mirada comunicacionaldesarrollando un recorrido histórico de laparticipación ciudadana durante los 30 añosde democracia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240112,"idioma_id":4,"titulo":"Further insight on recombination losses in the intrinsic layer of a-Si:H solar cells using computer modeling tools","resumen":"Recombination losses of a-Si:H based p-i-n solar cells in the annealed state are analyzed with device computer modeling. Under AM1.5 illumination, the recombination rate in the intrinsic layer is shown to be controlled by a combination of losses through defect and tail states. The influence of the defect concentration on the characteristic parameters of a solar cell is analyzed. The impact on the light current-voltage characteristic curve of adopting very low free carrier mobilities and a high density of states at the band edge is explored under red and AM1.5 illumination. The distribution of trapped charge, electric field, and recombination loses inside the intrinsic layer is examined, and their influence on the solar cell performance is discussed. Solar cells with intrinsic layers deposited with and without hydrogen dilution are examined. It is found that the photocurrent at &#8722;2 V is not always a good approximation of the saturated reverse-bias photocurrent in a-Si:H p-i-n solar cells at room temperature. The importance of using realistic electrical parameters in solar cell simulations is emphasized.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240115,"idioma_id":4,"titulo":"Obtainment of the density of states in the band tails of hydrogenated amorphous silicon","resumen":"In this work, we present two new pairs of formulas to obtain a spectroscopy of the density of states (DOS) in each band tail of hydrogenated amorphous silicon (a-Si:H) from photoconductivity-based measurements. The formulas are based on the knowledge of the small-signal recombination lifetime T', the characteristic decay time of the concentration of trapped carriers generated in excess bythe illumination, and that can be measured by methods like the Oscillating Photocarrier Grating (OPG) or Moving Grating Technique (MGT). First, we deduce the formulas and test their accuracy by numerical simulations using typical a-Si:H parameters. Next, we characterize an a-Si:H sample using well-known methods, like Fourier transform photocurrent spectroscopy to evaluate the valence band tail and modulated photoconductivity to measure the conduction band tail. We also performed measurements of steady-state photoconductivity, steady-state photocurrent grating and MGT, for a range of generation rates. From these measurements?and taking typical values for the capture coefficients, the extended states mobilities and the DOS at the band edges?we apply the new formulas to get the band tails. We find that the results obtained from the application of our formulas are in good agreement with those found with the raditional methods for both band tails. Moreover, we show that MGT\/OPG measurement to get T' can be avoided if one of the band tails is measured by one of the traditional methods, since the known band tail can be used to evaluate T' with one pair of equations, and then the other pair can be applied to get the other band tail.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240116,"idioma_id":5,"titulo":"Utilización del protocolo Co-Synch (5 días) combinado con un dispositivo intravaginal con progesterona para implementar una IATF en vacas con cría.","resumen":"El objetivo del presente trabajo fue evaluar el efecto del tratamiento Co-Synch combinado con un dispositivo intravaginal(DIV) con 1 g de progesterona colocado durante 5 días sobre el porcentaje de preñez a la IATF en vacas con cría.Secundariamente se evaluó el efecto de la estructura ovárica predominante (EOp) y de la condición corporal (CC) sobre dicho parámetro. Las hembras (n=210; CC=4,6±0,7) (escala 1 al 9) fueron distribuidas a: GrupoCo-SynchDispositivo5D (n=105); día 0, DIV + 0,10 mg de acetato de Buserelina (B). Día 5, retiro del DIV + 0,5 mg de cloprostenol sódico (CLO), 12 h más tarde 0,5 mg de CLO y 72 h pos-retiro DIV: IATF + 0,10 mg de B. GrupoDispositivo7D (n=105); día 0, DIV + 2 mg de benzoato de estradiol. Día 7, retiro del DIV + 1 mg de cipionato de estradiol + 0,5 mg de CLO y 48 hs pos-retiro DIV: IATF + 0,10 mg de B. Diagnóstico de gestación por ecografía (42 días pos-IATF). La tasa de preñez fue menor (P0,05) de la CC sobre la tasa de preñez; sin embargo, las tasas de preñez en vacas con cuerpo lúteo (40,0%) o con folículo grande (&#8805;10 mm; 40,0%) fueron mayores (P<0,05) que aquella obtenida en vacas con folículos pequeños (<10 mm; 23,7%). En conclusión, el protocolo Co-Synch Dispositivo 5D afecta negativamente el porcentaje de preñez comparado con el protocolo Dispositivo 7D en vacas con cría.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240117,"idioma_id":4,"titulo":"Characterization of the HIV-1 Subtypes present in Córdoba (Argentina) from nearly the beginning of the infection, using the Pol and Env genes.","resumen":"Objective: Identify the HIV-1 subtypes circulating in Córdoba, Argentina, in the period 1986-2001. Methods: Sequences of the pol and env genes from strains of Córdoba were compared with those of the HIV-1 M-group (several subtypes and circulating recombinant forms). Then, to determine if Cordoba?s subtypes had a single or multiple geographic origins, sequences were subdivided into pure-subtype data sets (avoiding the effects of recombination) and compared with sequences of diverse geographic origin. Results: Eighteen strains were subtype B, seven B\/F1, one C and one F1. The B\/F1 were: two CRF12_B\/F1 and five unique recombinant forms (URF_B\/F1). Córdoba?s subtype B would have multiple geographic origins, while subtypes F1 and C would have been introduced from Brazil or from Buenos Aires. Conclusions: The HIV-1 infection in Córdoba was complex since its very beginning and reveals its close contact, through tourism and commercial activities, with Buenos Aires and Brazil.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240119,"idioma_id":4,"titulo":"Methodology for the assessment of brucellosis management practices and its vaccination campaign: example in two Argentine districts","resumen":"Background: In Argentina, vaccination with Brucella abortus Strain 19 vaccine is mandatory. The objective of thestudy was to develop and test a method for evaluating, in an innovative way, some farmers? and veterinarians?management practices in relation to brucellosis and to assess the vaccination campaign and coverage. The worktook place in Brandsen and Navarro districts. Four questionnaires were designed (for officials from Local SanitaryEntities, vaccinators, vet practitioners and farmers). Responses were coded as ?ideal? (0) and ?not ideal? (1). To assessthe relative weight of each question (?item?), experts ranked the items according to their impact on managementpractices and vaccination. A weighted score was then calculated. A higher weighted score was assigned to theworse practices. Farmers obtaining a global weighted score above the third quartile were classified as ?inappropriatelymanaged farms?, to be compared per type of production system and district. To assess the immunization coverage,female calves were sampled 30 to 50 days post vaccination; they were expected to react positively to serologicaldiagnostic tests (DT+).Results: There were significantly more inappropriately managed farms and higher global scores among beef farmersand in Brandsen. Eighty three percent (83%) of female calves were DT+, significantly under the ideal immunizationcoverage (95%). Only 48% of farms were considered well vaccinated. DT+ results were positively associated with theBrandsen district (OR = 25.94 [4.60?1146.21] and with the farms having more than 200 cow heads ((OR = 78.34 [4.09?1500.00]). On the contrary, DT+ were less associated with vaccinators being veterinary practitioners (OR = 0.07 [0.006?0.78]). Farmers are well advised by their veterinary practitioners but they should improve some management practices.Conclusions: The vaccination campaign is globally well implemented, but the immunization coverage and somevaccinators? practices should be improved.This study leads to a better understanding of the most common used management and control practices regardingbrucellosis, which affect its epidemiology. Any vaccination campaign should be periodically assessed to highlightpossible fails. The described methodology can be extrapolated to other countries and different contexts.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240120,"idioma_id":5,"titulo":"Ovejas apartadas: Sexualidades disidentes, religiosidad y familia","resumen":"El artículo se propone analizar las negociaciones entre la creencia y la sexualidad a través de relatos biográficos de dos mujeres que mantienen relaciones sexo-afectivas con otras mujeres y que se identifican como creyentes cristianas.Considerando que las instituciones religiosas en América Latina juegan un rol importante a la hora de prescribir ciertos modos de vivir la sexualidad dentro de la norma familiar, heteronormativa y reproductiva, nos interesa acceder a ese universo de sentidos en el cual se tensionan y negocian los modos de creer y de vivir la sexualidad. Haremos  hincapié en la categoría nativa de ?cristiano apartado? y se reflexionará sobre el control de la sexualidad en los espacios religiosos y familiares.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240121,"idioma_id":5,"titulo":"Prácticas Tuteladas: masculinidad y  adultocentrismo en la decisión del aborto","resumen":"En el presente arti&#769;culo, abordamos la violencia de ge&#769;nero en lo que concierne a la coaccio&#769;n que vivieron mujeres para practicarse un aborto. A partir de estas experiencias, recuperadas de entrevistas realizadas para una investigacio&#769;n interdisciplinar sobre aborto y religiosidad (2015-2018), analizamos dos relaciones de subalternidad que expropian a la mujer de la decisio&#769;n del aborto. En primer lugar, se identifica las formas en que la masculinidad hegemo&#769;nica se vuelve violencia e imposicio&#769;n sobre el cuerpo de las mujeres. En segundo lugar, la situacio&#769;n de las mujeres cuyo aborto fue decidido, e incluso implementado, por miembros de la familia, en particular por la madre. Finalmente, concluimos que la ilegalizacio&#769;n del aborto no so&#769;lo profundiza las desigualdades de clase existentes, ya que conduce a las mujeres que quieren abortar a la clandestinidad, sino que tambie&#769;n las arroja a las decisiones de terceros, siendo la violencia de ge&#769;nero y el tutelaje consecuencias de la ilegalizacio&#769;n de su pra&#769;ctica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240123,"idioma_id":4,"titulo":"Vulnerability of mixotrophic algae to nutrient pulses and UVR in an oligotrophic Southern and Northern Hemisphere lake","resumen":"Nutrient inputs andultraviolet radiation (UVR) are global factors affecting the structure andfunctioning of aquatic ecosystems, particularly clear-water ecosystems. Weperformed experiments in two model lakes highly exposed to UVR fluxes in orderto test the effect that future increases in mineral nutrients transported bydust aerosol might exert on primary producers depending on the likelihood ofatmospheric inputs. Lake La Caldera (Northern Hemisphere) has been receivingrecurrent dust inputs from the Sahara Desert while lake Los Cántaros (SouthernHemisphere) has been less affected by dust aerosol. UVR × Nutrient synergistically stimulated primary production(PP), chlorophyll a (Chl a), with a smaller increase in phytoplanktonic biomass in La Caldera, butnot in Los Cántaros, where nutrient addition unmasked the UVR inhibitory effecton phytoplankton. The proportional decrease of mixotrophic nanoflagellates(MNFs) after the nutrient pulse (in Los Cántaros) and the long-term decline ofMNFs in La Caldera associated with the increase in aerosol-dust intrusions fromthe Sahara during the last 40 years suggest that a future scenario ofintensified aerosol events from desert and desertified areas would not onlyreduce functional diversity with the decline of MNFs, but would ultimatelyalter the C flux towards the grazing chain in oligotrophic ecosystems.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240124,"idioma_id":4,"titulo":"Global change effects on plankton community structure and trophic interactions in a Patagonian freshwater eutrophic system","resumen":"The short- and mid-term effects of a simulated global change scenario (i.e., Future) of increased nutrients, acidification, and solar radiation, in the presence or absence of grazers, were evaluated on a freshwater plankton community of Patagonia, Argentina. We used a cluster experimental design with microcosms incubated outdoors simulating the in situ (i.e., Present) and the Future conditions. Short-term changes in net productivity and respiration, together with mid-term changes in the community (abundance, biomass, and phytoplankton cell size) were measured. Phytoplankton had lower net productivity and higher respiration and zooplankton had, in general, higher respiration under the Future than that under the Present condition when organisms were exposed to UVR. The mid-term impacts of the Future condition were neither significant on zooplankton abundances, nor in phytoplankton abundances, biomass, and cell size. Nevertheless, the zooplankton&ndash;phytoplankton interaction strength was greater under the Future condition. Zooplankton exerted a strong top-down pressure, regardless of the experimental scenarios, grazing preferentially on small phytoplankton cells, thus decreasing their abundances and biomass. Overall, there were significant short-term impact of our Future global change scenario; however, its effects on mid-term time scales were not significant, and indeed, the zooplankton top-down pressure was the main driver that shaped the phytoplankton community.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240130,"idioma_id":4,"titulo":"Influence of pH on viscoelastic properties of heat-induced gels obtained with a b-Lactoglobulin fraction isolated from bovine milk whey hydrolysates","resumen":"A &#946;-Lactoglobulin fraction (r-&#946;Lg) was isolated from whey hydrolysates produced with cardosins from Cynara cardunculus. The impact of the hydrolysis process on the r-&#946;Lg structure and the rheological properties of heat-induced gels obtained thereafter were studied at different pH values. Differences were observed between r-&#946;Lg and commercial &#946;-Lg used as control. Higher values for the fluorescence emission intensity and red shifts of the emission wavelength of r-&#946;Lg suggested changes in its tertiary structure and more solvent-exposed tryptophan residues. Circular dichroism spectra also supported these evidences indicating that hydrolysis yielded an intermediate (non-native) &#946;-Lg state.The thermal history of r-&#946;Lg through the new adopted conformation improved the microstructure of the gels at acidic pH. So, a new microstructure with better rheological characteristics (higher conformational flexibility and lower rigidity) and greater water holding ability was founded for r-&#946;Lg gel. These results were reflected in the microstructural analysis by scanning electron microscopy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240131,"idioma_id":4,"titulo":"Platform design for extraction and isolation of Bromelain: Complexformation and precipitation with carrageenan","resumen":"The main objective of this work was to investigate for the first time the molecular mechanism of com-plex formation between bromelain (a positively charged enzyme) and carrageenan (a natural strongpolyelectrolyte, negatively charged) using spectroscopy techniques and thermodynamic approaches. TheBromelain-Carrageenan complex showed a maximal non-solubility at pH around 5.1. The solubility wasdependent on pH and ionic strength of the medium. To re-dissolve the formed complex, the pH waschanged and 500 mM of NaCl was added to the initial solution, proving the columbic mechanism forthe formation of non-soluble complex. The formation of the carrageenan-bromelain complex increasedin 8&#9702;C the enzyme thermal stability, while its biological activity was not modified. The amount of totalenzyme recovered in solution after precipitation with around 0.08% w\/v of carrageenan was 85?90%.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240132,"idioma_id":4,"titulo":"Molecular mechanism of lysozyme adsorption onto chemically modified alginate guar gum matrix","resumen":"The equilibrium isotherms and adsorption kinetics of lysozyme (LZ) on epichlorohydrin (Epi) cross-linked alginate-guar gum (Alg-GG) matrix were studied. Adsorption kinetics followed a pseudo-first-order model while the equilibrium isotherm could be represented by the Freundlich equation. The maximal amount of LZ adsorbed onto this matrix was around 2.4 mg per g of hydrated matrix at pH 7.00.The adsorption mechanism was associated to a simple diffusion process with a weak columbic interaction between LZ and the matrix. The presence of NaCl 0.3 M induced a total displacement of the LZ from the matrix. Under this condition, the percentage of desorbed protein was 95%. Successive cycles ofadsorption-washing-elution were performed and the results showed the reversibility of the process and the usefulness of the method for enzyme purification and separation. A last successful step was carriedout for the purification of LZ from egg white as natural source. The model proved to be useful applied as a platform design in the isolation and purification of proteins.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240136,"idioma_id":4,"titulo":"Deviation from the mean in teaching uncertainties","resumen":"In this work we present two simple and interactive web-based activities for introducing students to the concepts of uncertainties in measurements. These activities are based on the real-time construction of histograms from students measurements and their subsequent analysis through an active and dynamic approach.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240137,"idioma_id":5,"titulo":"La Impugnación de los actos procesales en el Proyecto","resumen":"El Proyecto de Código Procesal General para la justicia no penal de Iberoamécia elaborado por el Dr. Adolfo Alvarado Velloso, propone de manera sistémica la regulación de los distintos supuestos de impugnación de los actos procesales, incluyendo la inadmisibilidad, la inoponibilidad y finamente la anulabilidad. Deja en claro que todas las nulidades procesales son de tipo relativo, por ello, suprime la noción de acto inexistente así como la posibilidad de actos nulos de nulidad absoluta. Finamente guía al operador jurídico paso a paso para lograr la declaración de invalidez de un acto","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240138,"idioma_id":4,"titulo":"Temporal variability of ENSO effects on corn yield at the central region of Argentina","resumen":"The yield of corn is strongly affected by climatic conditions during the growing season. In the central region of Argentina, this crop is mainly managed under rainfed conditions. Hence, in most years, it is subjected to drought at some period during the growing season. El Niño Southern Oscillation (ENSO) is known to influence rainfall in this region, mainly during the warm semester, hence affecting summer crops yields. This study assessed the relationship between ENSO [analysed through the June?July?August Oceanic Niño Index (JJA-ONI)] and corn yields in the provinces of Buenos Aires, Entre Ríos and Santa Fe, which is the main corn-growing area in Argentina. This was performed for two contrasting periods regarding technology applied in the agricultural sector: 1972?1991 and 1992?2012. Remarkable increases in corn yield between periods were found for the entire region. Except for the province of Entre Ríos, we found statistically significant differences between periods in the trends of corn yield by performing the Chow test. Significant correlations (P < 0.01) between the JJA-ONI and corn yield were found in many counties of Buenos Aires, Entre Ríos and Santa Fe provinces. The correlation was higher in the second period for most counties. We consider that two hypotheses could explain this correlation increase: (1) in previous decades the best growing seasons (from a climatic point of view) were not fully exploited because of a low use of inputs and technology; and (2) the correlation between the ONI and rainfall could have increased in the last decades. We confirmed the latter hypothesis with rainfall data from conventional meteorological stations of 11 locations of the region under analysis. The JJA-ONI assessed in this research is available before farmers make their most relevant corn management decisions (fertilizer dose, sowing date, density, etc.), thus making this index highly valuable.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240139,"idioma_id":4,"titulo":"Techno-economic Assessment of Biomass Gasification of Spartina argentinensis","resumen":"Argentina has rangelands with high biomass production and low profitability such as the «Bajos Submeridionales», a depressed33,000 km2 area mostly dominated by a perennial grass, Spartina argentinensis. In this work, we assessed the technoeconomicfeasibility of S. argentinensis pellets gasification for combined heat and power purposes. The energy balance wasestimated, resulting in an Energy Return On Investment (EROI) of 5.43. Breakeven energy price (BEPE) was calculated for:(i) business as usual (BAU) and (ii) alternative scenario (AS) considering an international natural gas price of 0.2 and 0.47USD.m-3 respectively. Investment net present value (NPV) was calculated and a sensitivity analysis was performed. BEPEresulted in 149 and 126.2 USD.MWeh-1 for BAU and AS respectively. NPV was -4.4 and -1.6 million dollars for BAU and ASrespectively, showing the relevance of natural gas price on economic results. Power efficiency and electricity selling price werethe variables with higher impact on NPV.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240142,"idioma_id":5,"titulo":"Control posicional de malezas del entresurco","resumen":"Las malezas son los organismos que mayoresdaños económicos generan en los sistemasde producción agrícolas de nuestra región,tanto por la merma en los rendimientos comopor los costos asociados a su control. En losúltimos años, el manejo de malezas se habasado fundamentalmente en controlesquímicos con pulverizaciones terrestres oaéreas. Asociado a la liberación al mercado decultivos resistentes a glifosato, se ha idoreduciendo la cantidad de principios activosutilizados para el control de malezas ejerciendopresión de selección sobre biotipos toleranteso resistentes a estos principios activos.La deriva de las gotas ocasionada por el vientopuede afectar a cultivos vecinos susceptibles,especies no blanco (abejas, aves, etc.) asícomo a la salud de la población que habita enzonas adyacentes a lotes pulverizados. Porello, el creciente uso de fitosanitarios estágenerando tensiones de público conocimientoentre productores y habitantes de las cercaníasa los campos agrícolas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240145,"idioma_id":5,"titulo":"Imaginario racial, nación y familia en las novelas de Juana Manso","resumen":"El ensayo propone una teorización sobre lo imaginario racial desde una perspectiva comparada, a partir de las dos novelas de la escritora argentina Juana Paula Manso de Noronha, Los misterios del Plata. Episodios históricos de la época de Rosas. Escritos en 1846 (Rio de Janeiro, 1852) y La familia del comendador (Buenos Aires, 1854). La condición de exilio de Manso hace posible desarrollar una concepción dinámica de la imaginación racial a partir del análisis de diversas ideas y problemas raciales, como la degeneración, la pureza de sangre, el mestizaje y la esclavitud, en dos escenarios sociales y políticos diferentes. Estas ideas impulsan la construcción de narrativas fundacionales por parte de una mujer que tuvo injerencia institucional sobre la nación y la familia. Se adopta una perspectiva poscolonial que permite advertir la transcripción de lo racial como problema social y político a lo racial como problema biológico durante la transición de la colonia a la nación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240146,"idioma_id":5,"titulo":"Mestizaje, hibridez y transmedialidad. Categorías en tensión en performances y prácticas fronterizas de Guillermo Gómez Peña y La Pocha Nostra","resumen":"El artículo aborda tres categorías, mestizaje, hibridez y trasnmedialidad, a partir de las prácticas fronterizas de Guillermo Gómez Peña y el grupo de performance La Pocha Nostra. Se propone acercar la categoría de transmedialidad a una serie de preguntas sobre los imaginarios raciales y culturales latinoamericanos que he articulado en otros escritos, especialmente con relación a las categorías de mestizaje e hibridez. Así como mestizaje e hibridez han sido usadas para construir identidades culturales ?estables? y han sido teorizadas para deconstruir esas mismas identidades (Bhabha, Pérez Torres), la transmedialidad pareciera reproducir un movimiento si no idéntico, similar en agunos aspectos, algo que la obra de Gómez Peña sugiere por medio de una yuxtaposición constante de las tres categorías. La exacerbación de la transmedialidad en la obra en yuxtaposición permanente con el mestizaje y la hibridez abre preguntas sobre los alcances y efectos políticos de los dispositivos transmediales, poniendo sobre el tapete preguntas de orden político sobre el control de los cuerpos, los movimientos migratorios, el imperialismo, el colonialismo, la globalización.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240147,"idioma_id":4,"titulo":"Evidence of positive selection towards zebuine haplotypes in the BoLA region of Brangus cattle","resumen":"The Brangus breed was developed to combine the superior characteristics of both of its founder breeds, Angus and Brahman. It combines the high adaptability to tropical and subtropical environments, disease resistance, and overall hardiness of Zebu cattle with the reproductive potential and carcass quality of Angus. It is known that the majorhistocompatibility complex (MHC, also known as bovine leucocyte antigen: BoLA), located on chromosome 23, encodes several genes involved in the adaptive immune response and may be responsible for adaptation to harsh environments. The objective of this work was to evaluate whether the local breed ancestry percentages in the BoLA locus of a Brangus population diverged from the estimated genome-wide proportions and to identify signatures of positive selection in this genomic region. For this, 167 animals (100 Brangus, 45 Angus and 22 Brahman) were genotyped using a high-density single nucleotide polymorphism (SNP) array. The local ancestry analysis showed that more than half of the haplotypes (55.0%) shared a Brahman origin. This value was significantly different from the global genome-wide proportion estimated by cluster analysis (34.7% Brahman), and the proportion expected by pedigree (37.5% Brahman). The analysis of selection signatures by genetic differentiation (FST) andextended haplotype homozygosity-based methods (iHS and Rsb) revealed ten and seven candidate regions, respectively. The analysis of the genes located within these candidate regions showed mainly genes involved in immune response-related pathway, while other genes and pathways were also observed (cell surface signaling pathways, membrane proteins and ion binding-proteins). Our results suggest that the BoLA region of Brangus cattle may have been enriched with Brahman haplotypes as a consequence of selection processes to promote adaptation to subtropical environments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240148,"idioma_id":4,"titulo":"Creating chimeras: Embryonic stem cells, incorporated","resumen":"Genemodification within the murine genome has become a powerful and invaluable toolto investigate development. One example of the utility of such technology isproviding a method by which researchers can follow cells throughout developmentvia the introduced genetic modifications. This image depictsa Day-4.5 hatching mouse embryo (C57BL\/6J), with fluorescent cells visible inthe inner cell mass. The blastocyst was microinjected at Day 3.5 withfluorescently tagged mouse embryonic stem cells. Twenty-four hourspost-injection, these embryonic stem cells can be seen integrated into the hostblastocyst. These cells may subsequently incorporate into the mammalian germ line,allowing transmission of the transgene to subsequent generations. The authorswish to thank members of the Reproductive and Developmental Biology Laboratory ofthe National Institute of Environmental Health Sciences (NIEHS) for their insightand technical assistance. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240149,"idioma_id":4,"titulo":"Capturing Chaotic Chromosomes: Pairing in Action","resumen":"Accurate chromosome segregation is critical for the formation of haploid gametes, and therefore healthy offspring. Errors in segregation result in aneuploidy, which increases exponentially with maternal age (Hassold and Hunt, 2001). Maternally aged mouse oocytes were recently found to exhibit premature sister chromatid separation due to reduced levels of Securin, an essential regulator of sister chromatid cohesion (Nabti et al, 2017).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240150,"idioma_id":5,"titulo":"La censura en La Celestina: algunas reflexiones","resumen":"En este  articulo, rfelexiona sobre la censura en La Celestina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240152,"idioma_id":5,"titulo":"'Tanto animo e impetu tenian, que todos los caminos vieron su presencia: Mujeres, peregrinacion y Cruzadas","resumen":"Esta Conferencia plenaria se propone re-visitar la categoría mujeres en relación con las peregrinaciones y Cruzadas que para el colectivo mujeres significó desplazamiento físico  y místico-espiritual en el marco de una peregrinatio  a los lugares Santos,  realizado en una relativa seguridad  en la Alta edad media mientras que ya en la Baja, sobre todo a partir del siglo XII con las Cruzadas,  la peregrinatio  estuvo enmarcada y teñida  con frecuencia de  codicia, belicosidad, luchas entre los jefes cruzados y sus ejércitos,  saqueos y turbulencias  entre las que figuraron las mujeres que formaron parte de aquellos contingentes que apoyaron la Guerra santa de los ejércitos cristianos. De una u otra forma, las peregrinaciones y Cruzadas sacaron a muchas féminas de los lugares legitimados tradicionalmente para la vida femenina y les brindó  otros espacios, horizontes,  expectativas y necesidades que, poco frecuentes en la vida que habían llevado en las cortes, monasterios, burgos o villas, las enfrentó  con otros mundos y con el de ellas mismas, vividos desde otro lugar. En este marco, proponemos realizar  una cala en el universo femenino que se relacionó directa e indirectamente con peregrinaciones y con las Cruzadas y que confirma que estas también fueron ?cosa de mujer?.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240153,"idioma_id":5,"titulo":"'Tanto animo e impetu tenian, que todos los caminos vieron su presencia: Mujeres, peregrinación y Cruzadas","resumen":"este articulo re-visita la categoría mujeres en relación con las peregrinaciones y Cruzadas que para el colectivo mujeres significó desplazamiento físico  y místico-espiritual en el marco de una peregrinatio  a los lugares Santos,  realizado en una relativa seguridad  en la Alta edad media mientras que ya en la Baja, sobre todo a partir del siglo XII con las Cruzadas,  la peregrinatio  estuvo enmarcada y teñida  con frecuencia de  codicia, belicosidad, luchas entre los jefes cruzados y sus ejércitos,  saqueos y turbulencias  entre las que figuraron las mujeres que formaron parte de aquellos contingentes que apoyaron la Guerra santa de los ejércitos cristianos. De una u otra forma, las peregrinaciones y Cruzadas sacaron a muchas féminas de los lugares legitimados tradicionalmente para la vida femenina y les brindó  otros espacios, horizontes,  expectativas y necesidades que, poco frecuentes en la vida que habían llevado en las cortes, monasterios, burgos o villas, las enfrentó  con otros mundos y con el de ellas mismas, vividos desde otro lugar. En este marco, proponemos realizar  una cala en el universo femenino que se relacionó directa e indirectamente con peregrinaciones y con las Cruzadas y que confirma que estas también fueron ?cosa de mujer?.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240155,"idioma_id":5,"titulo":"Arqueología de los Bajos Submeridionales: sitios con hornos de tierra cocida en la localidad arqueológica Laguna La Blanca (La Criolla, Departamento San Justo, Provincia de Santa Fe)","resumen":"os ?hornitos de tierra cocida? son estructuras subterráneas de combustión cavadas en sedimentosdel Pleistoceno &#57344;inal (en Santa Fe, la Formación Tezanos Pinto) a partir de super&#57344;icies holocénicas. Son característicos de ambientes periestépicos como el Espinal, ecotono entre el ambiente chaqueño y el pampeano,y que conforman un amplio arco que nace en proximidades del río Paraná y se extiende por las provinciasde Chaco, Formosa, Santa Fe, Córdoba, la Rioja, Santiago del Estero, Tucumán, Mendoza y San Luis. No seencuentran hornos en la Mesopotamia, y aparentemente tampoco en la región pampeana en sentido estricto.Conocidos en la arqueología argentina desde comienzos del siglo XX, en 1999 Ceruti asignó los hornos y su contexto a una entidad arqueológica que denominó ?Esperanza?, integrante de una tradición cultural propia de la llanura central argentina, atribuida a comunidades pedestres que se desplazaban entre el Paraná y el borde de las Sierras Pampeanas en Córdoba y Cuyo. Cubren un amplio espacio temporal de 1.000 años (2000 a 1000 años AP) caracterizado por aridez generalizada, que &#57344;inaliza con la Etapa Húmeda Medieval. En la Provincia de SantaFe, la Localidad Arqueológica Laguna La Blanca se destaca como un enclave intermedio entre el paeleocauce delParaná y los a&#57344;luentes del Salado con siete sitios en que se detectaron al menos 395 hornos, con fechados de alrededor de 1000 años AP. Se sintetizan las investigaciones realizadas por los autores a partir de 1971 a &#57344;in de caracterizar la localidad arqueológic","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240164,"idioma_id":4,"titulo":"Physicochemical study of mixed systems composed by bovine caseinate and the galactomannan from Gleditsia amorphoides","resumen":"Model systemsformed by sodium caseinate (NaCAS) and espina corona gum (ECG) were studied. Therewas no evidence of attractive interactions between NaCAS and ECG macromolecules.Aqueous mixtures of NaCAS and ECG phase-separate segregatively over a wide rangeof concentrations. According to the images obtained by confocal laser scanning microscopy,NaCAS particles form larger protein aggregates when ECG is present in the system.An increase in the hydrodynamic diameter of NaCAS particles, as a result of ECGaddition, was also observed by light scattering in diluted systems.A depletion?flocculation phenomenon, in which ECG is excluded from NaCAS surface,is proposed to occur in the concentrated mixed systems, resulting in NaCAS aggregation.ECG raises the viscosity of NaCAS dispersions without affecting the Newtonian Flowbehaviour of NaCAS. These results contribute to improve the knowledge of a barely-studiedhydrocolloid which may be useful in the development of innovative food systems.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240165,"idioma_id":4,"titulo":"Effect of the espina corona gum on caseinate acid-induced gels","resumen":"Espina corona gum (ECG) is a galactomannan extracted from the seeds of a leguminous tree native to America. In spite of its potential application in the food industry, casein protein aggregation and gelation in systems containing this gum have not yet been characterized. Here, the effect of ECG on the aggregation and gelation of sodium caseinate (NaCAS) and on the microstructure, the mechanical properties and color of acid-induced gels were studied. The aggregation process of NaCAS was studied in the presence of calcium, sucrose and ECG. ECG caused an increase in the aggregation time, without modification of the aggregation pH. The presence of calcium produced an increase in the aggregation pH due to the neutralization of the negative charges of the protein surface, resulting in a decrease in the aggregation time. However, the time required for NaCAS gelification was not affected by the presence of ECG. NaCAS\/ECG mixed gels presented different color, water holding capacity and mechanical properties compared to NaCAS gels in the absence of ECG. Moreover, the presence of ECG produced differences in the microstructure of the acid-induced NaCAS gels.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240167,"idioma_id":5,"titulo":"Actividades colaborativas sobre conceptos de mecánica en sistemas físicos no puntuales","resumen":"Se presentan resultados de actividades llevadas a cabo por estudiantes delciclo inicial universitario, relacionadas con los conceptos de mecánica ensistemas físicos no puntuales. Dichas actividades se realizaron en el contexto dela modalidad de enseñanza denominada instrucciónentre pares, la cual involucra instancias de aprendizaje colaborativo. Laimplementación de esta modalidad pone especial énfasis en mejorar laconceptualización de los contenidos de física por parte de los estudiantes. Seutilizaron recursos tecnológicos que posibilitaron una retroalimentacióninmediata entre docentes y estudiantes y que permitieron detectar y discutir enel momento dificultades conceptuales generales. Los resultados encontradosalientan a continuar y ampliar la implementación de actividades del tipo que aquíse presenta; no obstante, del análisis de los mismos se desprenden advertenciasque son señaladas para alertar a aquellos docentes interesados en aplicar estametodología en sus clases de física.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240170,"idioma_id":5,"titulo":"Los límites de la gestión internacional de las provincias argentinas a partir de la reforma constitucional de 1994 y los avances previos en la constitución de la provincia de Jujuy","resumen":"El presente trabajoinvestigativo se propone describir y analizar las atribuciones y limitacionesde las provincias argentinas para la planificación y ejecución de la gestióninternacional, luego de la última reforma constitucional ocurrida en el año 1994.A tales efectos seanalizará las disposiciones reconocidas en el Artículo 124 de la ConstituciónNacionales, interpretando el sentido de su significado y alcance. El marcojurídico aportado luego de la reforma constitucional de 1994, reconoce a lasprovincias la capacidad de conducir una gestión internacional propia, en base asu carácter de preexistentes al Estado Nacional y dadas las facultades que hanreservado para sí mismas en el momento de la conformación del Estado argentino.No obstante, y dada la organización del Estado bajo la forma federal, sedesprenden condicionamientos destinados a moldear y coordinar la gestióninternacional de las provincias argentinas con la política exterior, materiareservada al gobierno federal.Por última, seanalizará el marco legal aportado por la Provincia de Jujuy respecto delreconocimiento y organización de su propia gestión internacional y sucongruencia con los principios del Estado federal argentino.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240171,"idioma_id":5,"titulo":"Especialización Institucional para la Gestión Internacional de la Provincia de Jujuy","resumen":"La presente propuesta investigativa sepropone estudiar la especialización institucional de las unidades subestatalespara la gestión internacional. El caso elegido es la provincia de Jujuy,Argentina, unidad subestatal fronteriza con un desarrollo activo de la gestióninternacional.La especialización institucional sepresenta como una manifestación de la evolución de la gestión internacional delas unidades subestatales. Esto se debe a los cambios introducidos por laglobalización y a la lectura que las unidades subestatales hacen del contextonacional e internacional. En este contexto la gestión internacional se presentacomo una vía de desarrollo para las unidades subestatales.La forma en que las unidades organizansus órganos de gobierno para canalizar sus objetivos de desarrollo en elcontexto internacional, muestra los intereses y las estrategias que empleanpara insertarse internacionalmente y alcanzar sus fines.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240172,"idioma_id":5,"titulo":"La condición de doble periferia en unidades subestatales","resumen":"Elpresente artículo investigativo se propone un acercamiento teórico al conceptode doble periferia como el condicionamiento que determina la gestióninternacional de algunas unidades subestatales Tal condicionamiento secircunscribe a las circunstancias ambientales, económicas y políticas quedeterminan un entorno desde el cual los departamentos, regiones, provincias,municipios, alcaldías, landers, entre otros, se sitúan y despliegan su accionarinternacional respecto del Estado del cual forman parte, y respecto del sistemainternacional. En el presente estudio se tomarán como casos la provincia deJujuy (Argentina), el departamento de Tarija (Bolivia) y la región de Tarapacá(Chile). La existencia de asimetrías en el sistema internacional y en elinterior de los Estados lleva a pensar en estructuras que condicionan ycaracterizan el accionar internacional de diversos actores, siendo las unidadessubestatales el centro de este estudio. La situación de doble periferia es elmarco desde el cual las unidades subestatales despliegan su gestión internacionalen búsqueda de oportunidades que permitan superar los condicionamientosestatales y sistémicos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240173,"idioma_id":5,"titulo":"Marco jurídico de la gestión internacional de las unidades subestatales. Un estudio comparado de Argentina, Bolivia y Chile","resumen":"Loscambios acaecidos en el sistema internacional y el posicionamiento de lasunidades subestatales como actores del mismo trae a escena el replanteamientodel rol del Estado en las relaciones internacionales. El presente trabajoinvestigativo se ocupará de analizar cómo se configura la gestión internacionalde las unidades subestatales de acuerdo al marco jurídico estatal. A los efectosde esta investigación se analizarán los casos de Argentina, Bolivia y Chile,haciendo especial referencia a las unidades subestatales de Jujuy, Tarija yTarapacá respectivamente. En tal sentido las preguntas que guían lainvestigación son: ¿En qué marco se configura la gestión internacional de lasunidades subestatales?¿Reconoce el Estado la gestión internacional de lasunidades que lo conforman? ¿De qué manera lo hace? ¿Qué tipo de relación seplantea entre el Estado y las unidades subestatales?Lacapacidad de las unidades subestatales para actuar de manera directa en elplano internacional ha sido reiteradamente reconocida, pero su fundamentojurídico se encuentra disperso a lo largo de las normas legales de cada Estadoy debe ser inferido del contexto, lo que implica que no existe un cuerpo legalgenérico que determine de forma explícita en qué forma pueden o no actuarinternacionalmente las unidades subestatales. De esta manera, la insercióninternacional de las unidades subestatales se verá afectada por el grado deautonomía que le otorgue el marco constitucional del Estado que conforman y porel marco de la política exterior.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240174,"idioma_id":5,"titulo":"LOS CONCEPTOS BÁSICOS INVOLUCRADOS EN LA ECUACIÓN DE ONDAS ARMÓNICAS MECÁNICAS: SU TRATAMIENTO EN LOS LIBROS DE TEXTO DE FÍSICA USADOS EN EL CICLO INICIAL UNIVERSITARIO","resumen":"En el ciclo inicial universitario se aborda el estudio de las ondas mecánicas transversales modelándolas matemáticamente a través de una función armónica de dos variables que involucra parámetros característicos cuya naturaleza física no es inmediata para los estudiantes. En este estudio se indaga, a través de un análisis de contenido, si los autores de los libros de Física usados frecuentemente en el ciclo inicial, presentan y explican adecuadamente el origen físico de dichos parámetros, de manera de facilitar a los estudiantes la conceptualización del fenómeno. Del trabajo realizado se desprende que muchos de los autores de los libros de textos analizados no hacen referencia, de un modo explícito, a la naturaleza de las magnitudes y parámetros involucrados, ni los relacionan con la fuente perturbadora y las propiedades del medio de propagación. Se mencionan algunas recomendaciones dirigidas a los docentes para el diseño de estrategias didácticas que favorezcan en los estudiantes la comprensión del fenómeno ondulatorio y su propagación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240175,"idioma_id":4,"titulo":"A novel HIF-1&alpha;\/VMP1-autophagic pathway induces resistance to photodynamic therapy in colon cancer cells","resumen":"Colon cancer is the third most frequent cancer and the fourth most common cause of cancer-related mortality worldwide and the standard therapy is surgical resection plus adjuvant chemotherapy. Photodynamic therapy (PDT) has been proposed as adjuvant therapy because it can prevent the tumor recurrence after surgical excision in colon cancer patients. Hypoxia is a common feature in solid tumor and leads to chemo\/radio resistance. Recently, it has been shown that in response to hypoxia cell can induce HIF-1&#945;-mediated autophagy to survive in this hostile microenvironment. Moreover, hypoxia and autophagy have been implicated in resistance to antitumor PDT. However, the molecular signals by which HIF-1&#945; induces autophagy in PDT context has not been studied yet. Here we evaluate theinterplay between HIF-1&#945; and autophagy as well as the underlying mechanism in the PDT resistance of colon cancer cells. Our study demonstrates that HIF-1&#945; stabilization significantly increases VMP1-related autophagy through binding to hypoxia responsive elements in VMP1 promoter. We show that HIF-1&#945;-induced utophagy increases colon cancer cell survival as well as decreses cell death after PDT. Moreover, here we demonstrate that HIF-1&#945;-induced autophagy is mediated by VMP1 expression, since downregulation of VMP1 by RNA interference strategy reduces HIF-1&#945;-induced autophagy and cell survival after PDT. In conclusion, PDT induces autophagy as a survival mechanism and the induction of the novel HIF-1&#945;\/VMP1\/autophagic pathway may explain, at least in part, theresistance of colon cancer cells to PDT. The knowledge of the molecular mechanisms involved in PDT resistance may lead to more accurate therapeutic strategies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240178,"idioma_id":5,"titulo":"Salud percibida y su relación con factores macrosociales e individuales en niños de dos departamentos de Tucumán, Argentina","resumen":"Introducción: El estudio de la calidad de vidarelacionada con la salud (CVRS) durantela infancia permite identificar factores quecondicionan el crecimiento y el desarrollo. Losobjetivos de este trabajo fueron: a) describir laCVRS de niños con edades comprendidas entre8,0 y 11,9 años que residían en la provincia deTucumán; y b) analizar si la CVRS variaba enrelación con factores macrosociales (calidad devida departamental, residencia urbano-rural, nivelsocioeconómico) e individuales (edad y sexo).Población y métodos: Estudio cuantitativo,transversal en escolares de los departamentos deYerba Buena y Simoca. Se aplicó el cuestionarioKIDSCREEN-52 para medir dimensiones de CVRSy las pruebas t de Student, análisis de la varianzay regresión logística multivariada para el análisissegún factores macrosociales e individuales.Resultados: Se analizaron 1647 encuestas. Losescolares de menor edad y los varones, engeneral, tuvieron una mejor percepción de susalud. Los residentes en Yerba Buena presentaronpuntuaciones medias significativamente más bajasen la dimensión recursos económicos, comparadoscon los de Simoca (45,3 vs. 46,7, p: 0,01). No huboasociación entre el nivel socioeconómico y laCVRS. Los niños rurales puntuaron más bajo enla mayoría de las dimensiones, con diferenciassignificativas en autopercepción (51,3 vs. 53,0,p: 0,01) y estado de ánimo (43,2 vs. 44,5, p: 0,03).Conclusiones: La salud percibida de los niños deYerba Buena y Simoca varió en relación a aspectosmacrosociales e individuales. En Yerba Buena, lapercepción de los recursos económicos fue peorrespecto de Simoca. En general, las apreciacionesde los niños urbanos fueron más favorables quelas de los rurales. Los varones y los escolares demenor edad percibieron mejor su salud.Palabras clave: calidad de vida, niños, área urbana,medio rural, salud.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240179,"idioma_id":4,"titulo":"Hexachlorobenzene alters cell cycle by regulating p27-cyclin E-CDK2 and c-Src-p27 protein complexes","resumen":"Hexachlorobenzene (HCB) is an organochlorine pollutant widely distributed in the environment around the entire world. Previous reports from our group and others have demonstrated that this compound is as an endocrine disruptor. We have also reported that HCB presents a co-carcinogenic effect in N-Nitroso-N-methyl-urea?induced mammary tumours in rats. In this work, we studied the effects of HCB on cell cycle progression and cell cycle regulating protein expression in the estrogen-sensitive breast cancer cell line, MCF-7. Here, we show that HCB alters cell cycle in a concentration-dependent way. The lowest assessed concentration (0.005 &#956;M) promotes the cell cycle progression, enhances cyclin D1 expression, and reduces the nuclear localization of p27 accompanied by an increased interaction between p27 and c-Src kinase. On the other hand, 5 &#956;M HCB delays the cell cycle progression and promotes the formation of the cyclin E-CDK2-p27 protein complex. Our results show that HCB stimulates cell proliferation through cell cycle modulation and c-Src involvement in MCF-7 cells. Here, we report for the first time that differential mechanisms of action of HCB on mammary cell cycle progression are triggered at different concentrations of this pollutant.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240181,"idioma_id":4,"titulo":"A dioxin-like compound induces hyperplasia and branching morphogenesis in mouse mammary gland, through alterations in TGF-&beta;1 and aryl hydrocarbon receptor signaling","resumen":"Hexachlorobenzene (HCB) is a widespread environmental pollutant and a dioxin-like compound that binds weakly to the aryl hydrocarbon receptor (AhR). Because AhR and transforming growth factor &#946;1 (TGF-&#946;1) converge to regulate common signaling pathways, alterations in this crosstalk might contribute to developing preneoplastic lesions. The aim of this study was to evaluate HCB action on TGF-&#946;1 and AhR signaling in mouse mammary gland, through AhR+\/+ and AhR-\/- models. Results showed a differential effect in mouse mammary epithelial cells (NMuMG), depending on the dose: 0.05 µM HCB induced cell migration and TGF-&#946;1 signaling, whereas 5 µM HCB reduced cell migration, promoted cell cycle arrest and stimulated the dioxin response element (DRE) -dependent pathway. HCB (5 µM) enhanced &#945;-smooth muscle actin expression and decreased TGF-&#946; receptor II mRNA levels in immortalized mouse mammary fibroblasts AhR+\/+, resembling the phenotype of transformed cells. Accordingly, their conditioned medium was able to enhance NMuMG cell migration. Assays in C57\/Bl6 mice showed HCB (3 mg\/kg body weight) to enhance ductal hyperplasia, cell proliferation, estrogen receptor &#945; nuclear localization, branch density, and the number of terminal end buds in mammary gland from AhR+\/+ mice. Primary culture of mammary epithelial cells from AhR+\/+ mice showed reduced AhR mRNA levels after HCB exposure (0.05 and 5 µM). Interestingly, AhR-\/- mice exhibited an increase in ductal hyperplasia and mammary growth in the absence of HCB treatment, thus revealing the importance of AhR in mammary development. Our findings show that environmental HCB concentrations modulate AhR and TGF-&#946;1 signaling, which could contribute to altered mammary branching morphogenesis, likely leading to preneoplastic lesions and retaining terminal end buds.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240187,"idioma_id":4,"titulo":"Health care importance of Treponema pallidum, Chagas' disease and Human immunodeficiency virus 1 among Amerindians of Argentina: an observational study","resumen":"The objective of this study was to estimate the prevalence of Treponema pallidum,Trypanosoma cruzi and Human immunodeficiency virus 1 (HIV-1) in five Amerindian populations of Argentina. A retrospective study was conducted among 857 Amerindian populations(112 Kollas, 298 Mbyá-guaraníes, 79 Sagua Huarpes, 368 Wichis) from 2007 to 2010. Screeningand confirmation of T. pallidum, T. cruzi and HIV-1 were performed. T. pallidum and T. cruziinfections were detected in all communities with an overall prevalence rate of 4.2% and 16.8%,respectively. Although HIV was not detected, syphilis and Chagas? disease represent a challenge for the health care system and the reinforcement of public health strategies is necessaryconsidering the socioeconomic isolation of these populations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240190,"idioma_id":5,"titulo":"`Es como que se me forma una burbuja acá´: Procedimientos metafóricos en la interacción cardiólogo-paciente?","resumen":"On the basis of conceptual metaphor theory and from the perspective of conversation analysis, this paper focuses on conceptual metaphors, metaphorical expressions, and the formulation efforts carried out by doctors and patients to communicate different aspects of cardiac crises.  The main questions articulated in this study are: How do interactants describe and reconstruct cardiac crises and associated events?  What role and relevance do metaphorical procedures have in those conversational tasks?  According to the discursive roles, is it possible to identify specificities in the selection of metaphor type, in the chosen procedures and formulation resources, and in the functions metaphors acquire in the exchanges?  The analysis is based on a corpus of conversations among cardiologists and patients that took place in different healthcare services institutions in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240195,"idioma_id":4,"titulo":"Partitioning of xylanase from Thermomyces lanuginosus in PEG\/NaCit aqueous two-phase systems: Structural and functional approach","resumen":"The structure and catalytic activity of xylanase from Thermomyces lanuginosus were studied in different media (containing polyethylene glycol -PEG- or salt) at different temperatures. The aim was to study how the native structure of the enzyme is affected to understand the partitioning behavior of xylanase in PEG\/sodium citrate (PEG\/NaCit) aqueous two-phase systems. The presence of PEGs of different molar masses slightly altered the native structure of xylanase, although its catalytic activity was not affected. All the polymers assayed protect the native structure (and catalytic activity) of xylanase against temperature,except for PEG1000. Surface hydrophobicity experiments showed that xylanase favorable interacts with PEGs. Partitioning experiments confirmed this result and demonstrated that PEG1000\/NaCit is the best system to partition xylanase from Thermomyces lanuginosus, since the Kp was 17.7 ± 0.3.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240198,"idioma_id":5,"titulo":"El existencialismo pol&iacute;tico en Martin Heidegger y Carl Schmitt","resumen":"El artículo examina afinidades entre Ser y tiempo y El concepto de lo político respecto de cuestiones metodológicas, la recepción de temáticas de la filosofía de la existencia y sobre la importancia conceptual y política del concepto de ?comunidad? en ambas obras. Se analiza la función metodológica que la idea de la muerte cumple en ambas teorías, señalando que ambas desembocan en un ateísmo práctico. El trabajo busca encontrar un suelo común a ambas obras que revele la ética compartida por ellas. Tanto Heidegger como Schmitt desarrollan una visión de la política como comunidad, la cual sólo es aludida en los textos a través de las imágenes de la camaradería de los soldados y la fusión nacionalista de los festejos por el inicio de la Primera Guerra Mundial. La seriedad, el riesgo y el heroísmo aparecen como los rasgos colectivos más salientes de una unión que se presenta como ?destino?. El estudio del pensamiento de Heidegger desde la perspectiva brindada por los conceptos del texto de Schmitt permite comprender los aspectos políticos del pensamiento del filósofo antes de su compromiso con el nacionalsocialismo y permite apreciar la fuerte impronta nacionalista subyacente a algunas de sus formulaciones ontológicas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240199,"idioma_id":4,"titulo":"Study of the martensitic transition in Ni-Mn-Sn-Ti ferromagnetic shape memory alloys","resumen":"In the present work, mechanical spectroscopy measurements as a function of temperature and strain have been performed in (at.%) Ni50Mn37Sn13-xTix (x=0, 0.5 and 2) ferromagnetic shape memory alloys in order both to study martensitic transition phenomenon and also to determine its temperature of appearance. For mechanical spectroscopy measurements, a five elements piezoelectric device recently developed has been used. In addition, other characterization techniques as, differential thermal analysis and superconducting quantum interference magnetic spectroscopy, were also used. Besides, relaxation processes near the martensitic transition temperature have been also observed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240201,"idioma_id":4,"titulo":"Evaluating management strategies in the conservation of the critically endangered Blue-throated Macaw ( Ara glaucogularis )","resumen":"We model the dynamics of the remaining wild population of the Blue-throated Macaw (Ara glaucogularis), a critically endangered and Bolivian endemic species exposed to different management strategies. The model becomes a tool to quantify how effective management actions may be. We construct a birth-pulse, post breeding census, deterministic, stage structured projection matrix model to describe the population dynamics. The model shows that population growth is sensitive to changes in the probability of survival in the adult stage, followed by changes in fertility. We describe the long-term behavior of the population as result of the combination of the maternity function and the nestlings? survival probability. Under the scenarios of increasing population, the number of years that are necessary to double the current wild population varied between 33 and 215 years without reintroduction, and between 7 and 46 years if 50 adult macaws are reintroduced ten years later since the simulation starts. Stakeholders of the Blue-throated Macaw Conservation Project may profit from a simple graphical tool based on this model for management decision making. By knowing the adult population size and the number of hatched eggs at the beginning of each breeding season, the field team could assess the necessary effort on nestlings? management to increase the chances of a positive population growth. Evaluating beforehand the impact of management actions on Blue-throated Macaws could contribute to the improvement and effectiveness of conservation actions on the critically endangered Blue-throated Macaw population.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240204,"idioma_id":5,"titulo":"Dosis de N sobre reflectancia espectral, contenido de clorofila y nutrientes en plantas de gerbera","resumen":"RESUMENEn cultivo sin suelo el manejo nutricional debe asegurar la concentración y el balance de los nutrientes, en orden a obtener alta productividad y calidad, a la vez que un ajuste fino de la fertilización contribuirá a reducir el impacto ambiental. Bajo la hipótesis de que hay para gerbera un nivel de N óptimo que permitirá expresar su máxima productividad potencial, y que a la vez podrá detectarse a través de una técnica no destructiva como la reflectancia del cultivo, así como también si hay variaciones de acuerdo con el momento del año, los objetivos de este trabajo fueron: 1) determinar el efecto de diferentes dosis de N sobre un cultivo sin suelo de gerbera, 2) detectar patrones de reflectancia espectral que permitan predecir deficiencias nutritivas, y 3) observar si en diferentes momentos del año hayvariaciones de la respuesta a las dosis de N. En un cultivo sin suelo de gerbera cv ?Sunway? para flor cortada, se ensayaron tres dosis de N, y se registró producción de flores, reflectancia espectral, área foliar y contenido de clorofila y nutrientes en hoja. La producción anual no se diferenció significativamente (110-113 flores\/m2\/año), sin embargo se encontraron diferencias en momentos puntuales en relación con la dosis de N, observándose mejores resultados de la dosis más alta en primavera (22 vs. 12 flores\/m\/mes), pero la dosis media mostró mejor respuesta en otoño (12 vs. 5 flores\/m2\/mes), mientras que en época invernal no hubo diferencias o bien estas no fueron cuantitativamente importantes (2 flores\/m2\/mes). A partir de la reflectancia se construyeron modelos que permitieron estimar el contenido de clorofila, de nitrógeno y el índice de área foliar (IAF) en forma no destructiva. El IAF podría servir como índice para el manejo nutricional, buscando mantener un IAF del orden de 3, 4 y 2 m2 hoja\/m2 suelo en otoño, invierno y primavera respectivamente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240205,"idioma_id":4,"titulo":"Global developments in forensic geology","resumen":"orensic geology has developed in each country depen- dent on the history, political and social setting, anthropo- logical influences and geology. The aim of this section is to provide a global overview of forensic geology, including the history, developments and future challenges in Africa, Asia, Australia, Canada, Europe, Middle East, Latin America and the Caribbean, Russia and Commonwealth Indepen- dent States (CIS), and USA.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240208,"idioma_id":5,"titulo":"BIOSILO DE RESIDUOS DE MERLUZA Y HARINA DE CEBADA FERMENTADOS CON BACTERIAS ÁCIDO LÁCTICAS SELECCIONADAS","resumen":"Suitability of Lactococcus lactis Tw34 and Lactobacillus plantarum Lb7 asbio-silage inoculants was studied. Experiments were carried out with a mixtureof hake (Merluccius hubbsi) by-products and barley meal fermentedduring 7 days. A sample acidified with lactic acid was used as control. Inbiological mixtures, the pH dropped below 5,0 after 2 days of fermentationand remained stable until the end of the experience. Maximum populations(> 109 CFU\/g) were reached after 5 days of incubation at 18°C. Water solublepeptides concentration increased during the 7 days of incubation andno significant differences (p  0,05). After 7 days, phosphorousconcentrations reached 2.26 and 2,42 g\/100 g in bio-silages fermented withLc. lactis Tw34 and Lb. plantarum Lb7, respectively, while control values remainsalmost stable (1,61 g\/100 g). At the end of the experience, inhibitoryactivity of trypsin was abolished in both bio-silage while in control sampleantinutritional factors remained active. The results indicated the feasibility ofthe use of the selected mixture as substrate for bio-silage production andthe effectiveness Lc. lactis Tw34 and Lb. plantarum Lb7 as inoculants.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240209,"idioma_id":4,"titulo":"Design, synthesis and biological evaluation of 1,3-dihydroxyxanthone derivatives: Effective agents against acetylcholinesterase","resumen":"The present work concerns the rational design and development of new inhibitors of acetylcholinesterase (AChE) based on the privileged xanthone scaffold. In order to understand and rationalize the mode of action of these target structures a theoretical study was initially conducted. From the results of rational design, a new variety of amphiphilic xanthone derivatives were synthesized, structurally characterized and evaluated as potential anti-Alzheimer agents. The results showed that most of the synthesized compounds exhibited high AChE inhibitory activity at the micromolar range (IC50, 0.46?12.09 &#956;M). The synthetic xanthone 11 showed the best inhibitory effect on AChE and a molecular modeling study revealed that 11 targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. Therefore, this compound could be considered as a potential lead compound towards new drugs for the treatment of Alzheimer?s disease.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240210,"idioma_id":4,"titulo":"Diversity and distribution of Lepidoptera-specific insecticidal genes in Bacillus thuringiensis strains from Argentina","resumen":"Atotal of 268 Bacillus thuringiensis strainsobtained from different sources of Argentina were analyzed to determine thediversity and distribution of cry1, cry2, cry8, cry9 and vip3A genes encoding forLepidoptera-specific insecticidal proteins. Twin strains were excluded. Tendifferent profiles were detected among the 80 selected B. thuringiensis. Two of these profiles (cry1Aa, cry1Ac, cry1Ia, cry2Aa, cry2Ab and vip3Aa (35\/80), and cry1Aa, cry1Ab, cry1Ac, cry1Ia, cry2Aa, cry2Ab and vip3Aa (25\/80)), pooled the 75% of the strains. The existence ofthis low diversity is a rarity, since in most of the studied collections agreat diversity of insecticidal gene profiles has been described. In addition,the more frequently detected profile was also more frequently derived from soil(70%), stored product dust (59%) and spider webs (50%). In contrast, the cry1Aa, cry1Ab, cry1Ac, cry1Ia, cry2Aa, cry2Ab and vip3Aa profile were mainly detected instrains isolated from leaves (40%) and death insect larvae (50%). Six of theidentified insecticidal gene profiles were discovered in strains isolated fromstored product dust and leaves indicating higher diversity of profiles in thesekinds of sources than in others. Some strains with high insecticidal activityagainst Epinotia aporema (Lepidoptera)larvae were identified, this being important to explore future microbialstrategies for the control of this crop pest in the region.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240211,"idioma_id":4,"titulo":"Accumulation of lead and associated metals (Cu and Zn) at different growth stages of soybean crops in lead-contaminated soils: food security and crop quality implications","resumen":"The Pb, Cu and Zn content, the physicochemical parameters in soils (EC, OM%, soil texture and pH) and the metal accumulation of Glycine max plants at different growth stages were evaluated. Topsoil and soybean samples were collected in the vicinity of a former battery recycling plant, with the results showing that only the concentrations of Pb in soils corresponding to sites located near to the lead emission source were above the maximumpermissible levels. However, soybean crops accumulated Pb above the permitted levels at all studied sites, revealing a potential toxicological risk for direct consumption. Thus, the accumulation of Pb in soybean was directly related to the translocation factor of the metal from roots to aerial parts of the plant. This was evidenced as a lower accumulation at early growth stages and a higher accumulation at maturity, with the distribution between organs coinciding with nutrient incorporation and remobilization in the plant. Moreover, the bioconcentration factor revealed that the bioaccumulation of lead in soybean was a consequence of the lead-recycling plant activity in the past. Taken together, results of the present study demonstrated that soybean crops can incorporate and accumulate potentiallytoxic metals, such as lead.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240218,"idioma_id":4,"titulo":"Accumulation of lead and associated metals (Cu and Zn) at different growth stages of soybean crops in lead-contaminated soils: food security and crop quality implications.","resumen":"The Pb, Cu and Zn content, the physicochemical parameters in soils (EC, OM%, soil texture and pH) and the metal accumulation of Glycine max plants at different growth stages were evaluated. Topsoil and soybean samples were collected in the vicinity of a former battery-recycling plant, with the results showing that only the concentrations of Pb in soils corresponding to sites located near to the lead emission source were above the maximum permissible levels. However, soybean crops accumulated Pb above the permitted levels at all studied sites, revealing a potential toxicological risk for direct consumption. Thus, the accumulation of Pb in soybean was directly related to the translocation factor of the metal from roots to aerial parts of the plant. This was evidenced as a lower accumulation at early growth stages and a higher accumulation at maturity, with the distribution between organs coinciding with nutrient incorporation and remobilization in the plant. Moreover, the bioconcentration factor revealed that the bioaccumulation of lead in soybean was a consequence of the lead-recycling plant activity in the past. Takentogether, results of the present study demonstrated that soybean crops can incorporate and accumulate potentially toxic metals, such as lead.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240223,"idioma_id":4,"titulo":"Galectin-1&ndash;Driven Tolerogenic Programs Aggravate Yersinia enterocolitica Infection by Repressing Antibacterial Immunity","resumen":"Yersinia enterocolitica is an enteropathogenic bacterium that causes gastrointestinal disorders, as well as extraintestinal manifestations. To subvert the host?s immune response, Y. enterocolitica uses a type III secretion system consisting of an injectisome and effector proteins, called Yersinia outer proteins (Yops), that modulate activation, signaling, and survival of immune cells. In this article, we show that galectin-1 (Gal-1), an immunoregulatory lectin widely expressed in mucosal tissues, contributes to Y. enterocolitica pathogenicity by undermining protective antibacterial responses. We found higher expression of Gal-1 in the spleen and Peyer?s patches of mice infected orogastrically with Y. enterocolitica serotype O:8 compared with noninfected hosts. This effect was prevented when mice were infected with Y. enterocolitica lacking YopP or YopH, two critical effectors involved in bacterial immune evasion. Consistent with a regulatory role for this lectin during Y. enterocolitica pathogenesis, mice lacking Gal-1 showed increased weight and survival, lower bacterial load, and attenuated intestinal pathology compared with wild-type mice. These protective effects involved modulation of NF-&#954;B activation, TNF production, and NO synthesis in mucosal tissue and macrophages, as well as systemic dysregulation of IL-17 and IFN-&#947; responses. In vivo neutralization of these proinflammatory cytokines impaired bacterial clearance and eliminated host protection conferred by Gal-1 deficiency. Finally, supplementation of recombinant Gal-1 in mice lacking Gal-1 or treatment of wild-type mice with a neutralizing anti-Gal-1 mAb confirmed the immune inhibitory role of this endogenous lectin during Y. enterocolitica infection. Thus, targeting Gal-1?glycan interactions may contribute to reinforce antibacterial responses by reprogramming innate and adaptive immune mechanisms.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240224,"idioma_id":4,"titulo":"Total Leishmania antigens with Poly(I:C) induce Th1 protective response.","resumen":"Aims: Our proposal was to develop a vaccine based on total Leishmania antigens (TLA) adjuvanted with polyinosinic-polycytidylic acid [Poly(I:C)] able to induce a Th1 response which can provide protection against Leishmania infection.Methods and Results: Mice were vaccinated with two doses of TLA-Poly(I:C) administered by subcutaneous route at three week interval. Humoral and cellular immune responses induced by the immunization were measured. The protective efficacy of the vaccine was evaluated by challenging mice with infective promastigotes of Leishmania (Leishmania) amazonensis into the footpad. Micevaccinated with TLA-Poly(I:C) showed a high anti-Leishmania IgG titer, as well as increased IgG1 and IgG2a subclass titers compared with mice vaccinated with the TLA alone. The high IgG2a indicated a Th1 bias response induced by the TLA-Poly(I:C) immunization. Accordingly, the cellular immune response elicited by the formulation was characterized by an increased production of IFN-&#947; and nosignificant production of IL-4. The TLA-Poly(I:C) immunization elicited good protection, which was associated with decreased footpad swelling, a lower parasite load and a reduced histopathological alteration in the footpad.Conclusion: Our findings demonstrate a promising vaccine against cutaneous leishmaniasis that is relatively economic and easy to develop and which should be taken into account for preventing leishmaniasis in developing countries.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240229,"idioma_id":4,"titulo":"Influence of land use on the taxonomic and functional diversity of dung beetles (Coleoptera: Scarabaeinae) in the southern Atlantic forest of Argentina","resumen":"The degradation and replacement of native ecosystems affects both their taxonomic and functional biodiversity. However, native species may find a gradient of habitat suitability in different land uses within a region. The aim of this study was to evaluate the effect of land use on the taxonomic and functional diversity of dung beetle assemblages in the southern Atlantic forest of Argentina. Dung beetles were sampled in both the native forest (control) and different land uses (Pine and Yerba mate plantations and cattle pastures) during the 2014 summer, using pitfall traps baited with human feces and rotten meat. Samplings were taken from 20 different sites, with five replicates of each land use and the native forest (100 pitfall traps in total). A total of 1699 beetles of 27 species were captured. Canthon quinquemaculatus, Canthon conformis and Dichotomius sericeus were the most abundant species. Cattle pastures were the land use most negatively affected in their taxonomic and functional diversity, particularly large paracoprid dung beetles. Pine plantations maintained their taxonomic and functional diversity in relation to the native forest and Yerba mate plantations showed, in general, an intermediate situation. Microclimatic conditions (average temperature and humidity and maximum temperature) were correlated with functional diversity (the proportion of large paracoprid dung beetles decreased with increasing temperature) and are probably good predictors to explain the observed patterns of functional diversity of dung beetles. The development of sustainable production systems that preserve the native biodiversity requires the conservation of key components from the ecological niche of native species, especially microclimatic conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240230,"idioma_id":4,"titulo":"Replacing trees by bamboos: Changes from canopy to soil organic carbon storage","resumen":"Disturbances such as selective logging in a forest may lead to a degradation process, where new species become dominant and replace the original vegetation. This is the case of the Semi-deciduous Atlantic Forest, where bamboos replace trees and palms, affecting the forest structure and dynamics. As bamboos show plant traits that contrast those of trees and palms, we hypothesize that forest degradation affects ecosystem properties, generating changes in litterfall and litter decay rates, which transfer from plants to soil. We tested this hypothesis in twelve 0.36 ha plots along a forest degradation gradient in the subtropical forest of Northeastern Argentina. Total litterfall did not change along forest degradation, but litter layer necromass decreased more than 60% and litter thickness doubled in highly degraded sites. Litter layer thickness was associated with bamboo necromass present in the litterfall. Forest degradation also caused a deceleration in decomposition of the two most contrasting litter types under study, while the soil organic carbon content in the top 5 cm suffered a 50% decrease, from 21.5 to 10.9 Mg ha&#8722;1. Forest degradation has a cascade effect on carbon storage and on its cycling from vegetation to soil by means of changes in different ecosystem processes mediated by plants. In the end, these changes affect soil organic carbon. This study provides a better understanding on the mechanisms behind carbon losses in relation to forest degradation, one of the greatest uncertainties in the carbon budget.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240237,"idioma_id":5,"titulo":"Aprendizaje autorregulado en el nivel universitario: Un estudio situado con estudiantes de psicopedagogía de diferentes ciclos académicos","resumen":"Ser capaz de autorregular adecuadamente el propio aprendizaje impacta positivamente en el rendimiento académico del alumnado. De aquí la relevancia de entender cuáles son, cómo se articulan y cómo cambian estrategias de aprendizaje y patrones de motivación en el transcurso de la formación académica. Los objetivos de este trabajo son: (a) describir estrategias cognitivas\/ metacognitivas de aprendizaje y patrones de motivación usadas por estudiantes (media y desviación estándar); (b) analizar las correlaciones entre ambos grupos de variables (correlación índice de Pearson); (c)contrastar resultados según Ciclo Básico (1° año) y Superior (5° año) deformación académica (prueba de hipótesis t de Student). El estudio cuantitativo ex post facto se basó en la administración de la versión argentina del MSLQ (Motivated Strategies Learning Questionnaire) denominada MSLQe a 114 estudiantes de psicopedagogía. Los resultados muestran: (a) un repertorio variado de estrategias y patrones de motivación para el aprendizaje; (b) un mayor uso de estrategias metacognitivas de autorregulación y estrategias de manejo del tiempo y ambiente de estudio se asoció a altos niveles en los patrones motivacionales de orientación a metas, valoración de la tarea,creencias de control y de autoeficacia del estudiantado; (c) diferencias significativas según el ciclo académico: a favor del alumnado principiante en estrategias cognitivas de repaso, autorregulación metacognitiva y organización;mientras que las puntuaciones fueron superiores para los alumnos y las alumnas avanzadas en relación a pensamiento crítico. Asimismo, respecto de los patrones de motivación, los grupos avanzados declararon mayores tendencias hacia metas de orientación intrínsecas, mientras que los principiantes lo hicieron en metas de motivación extrínsecas, creencias de control, de autoeficacia y ansiedad. Es posible concluir que la formación académica posibilitó una integración jerárquica tanto de estrategias superficiales y profundas, así como de patrones de motivación internos y externos del estudiantado. De este modo, este artículo contribuye a un análisis de dimensiones cognitivas (frías y cálidas) como contextualmente situado (niveles iniciales y finales de la formación académica)de las estrategias de aprendizaje y patrones de motivación de grupos universitarios de estudiantes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240242,"idioma_id":4,"titulo":"Accumulation of lead and associated metals (Cu and Zn) at different growth stages of soybean crops in lead contaminated soils: food security and crop quality implications.","resumen":"The Pb, Cu and Zn content, the physicochemicalparameters in soils (EC, OM%, soil texture and pH) andthe metal accumulation of Glycine max plants at differentgrowth stages were evaluated. Topsoil and soybean sampleswere collected in the vicinity of a former batteryrecyclingplant, with the results showing that only theconcentrations of Pb in soils corresponding to sites locatednear to the lead emission source were above the maximumpermissible levels. However, soybean crops accumulatedPb above the permitted levels at all studied sites, revealinga potential toxicological risk for direct consumption. Thus,the accumulation of Pb in soybean was directly related tothe translocation factor of the metal from roots to aerialparts of the plant. This was evidenced as a lower accumulationat early growth stages and a higher accumulationat maturity, with the distribution between organs coincidingwith nutrient incorporation and remobilization in theplant. Moreover, the bioconcentration factor revealed thatthe bioaccumulation of lead in soybean was a consequenceof the lead-recycling plant activity in the past. Takentogether, results of the present study demonstrated thatsoybean crops can incorporate and accumulate potentiallytoxic metals, such as lead.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240243,"idioma_id":4,"titulo":"Phytoextraction of Pb, Cr, Ni, and Zn using the aquatic plant Limnobium laevigatum and its potential use in the treatment of wastewater","resumen":"In order to study the bioaccumulation of Pb, Cr, Ni, and Zn and the stress response, the floating aquatic plant Limnobium laevigatum was exposed to increasing concentrations of a mixture of these metals for 28 days, and its potential use in the treatment of wastewater was evaluated. The metal concentrations of the treatment 1 (T1) were Pb 1 &#956;g L&#8722;1, Cr 4 &#956;g L&#8722;1, Ni 25 &#956;g L&#8722;1, and Zn 30 &#956;g L&#8722;1; of treatment 2 (T2) were Pb 70 &#956;g L&#8722;1, Cr 70 &#956;g L&#8722;1, Ni 70 &#956;g L&#8722;1, and Zn 70 &#956;g L&#8722;1; and of treatment 3 (T3) were Pb 1000 &#956;g L&#8722;1, Cr 1000 &#956;g L&#8722;1, Ni 500 &#956;g L&#8722;1, and Zn 100 &#956;g L&#8722;1, and there was also a control group (without added metal). The accumulation of Pb, Cr, Ni, and Zn in roots was higher than in leaves of L. laevigatum, and the bioconcentration factor revealed that the concentrations of Ni and Zn in the leaf and root exceeded by over a thousand times the concentrations of those in the culture medium (2000 in leaf and 6800 in root for Ni; 3300 in leaf and 11,500 in root for Zn). Thus, this species can be considered as a hyperaccumulator of these metals. In general, the changes observed in the morphological and physiological parameters and the formation of products of lipid peroxidation of membranes during the exposure to moderate concentrations (T2) of the mixture of metals did not cause harmful effects to the survival of the species within the first 14 days of exposure. Taking into account the accumulation capacity and tolerance to heavy metals, L. laevigatum is suitable for phytoremediation in aquatic environments contaminated with moderated concentrations of Cr, Ni, Pb, and Zn in the early stages of exposure.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240247,"idioma_id":5,"titulo":"Trayectorias profesionales de médicos y médicas proveedores de interrupción legal del embarazo en Argentina","resumen":"El presente estudio se propuso dar cuenta de la experiencia subjetiva de médicos\/as que proveen servicios de aborto legal en el sistema público de salud,  con foco en su trayectoria personal y profesional en el marco del proceso gradual de institucionalización de esta práctica. Se trata de un estudio exploratorio y cualitativo. La técnica de recolección de la información fue la entrevista en profundidad en el marco del uso del método biográfico. El estudio se planteó como un estudio de caso, en el que se examinaron situaciones únicas -en este caso, personas únicas-, cuyas experiencias personales y vitales se convirtieron en el instrumento y argumento centrales de análisis. El trabajo de campo fue realizado durante el primer semestre de  2014. Se realizaron entrevistas personales, previa obtención del consentimiento informado, en su mayoría en los lugares de trabajo de los profesionales, y vía Skype con los que residen fuera de la Ciudad de Buenos Aires. Las mismas fueron grabadas digitalmente y transcriptas en su totalidad.La muestra fue intencional y por bola de nieve. Fueron entrevistados 20 médicos\/as experimentados en la práctica de aborto no punible, de los cuales 17 son tocoginecólogos\/as y 3  médicos generalistas; 12 mujeres y 8 varones, de edades que oscilan entre 26 y 65 años. Ocho trabajan en hospitales de la Ciudad de Buenos Aires, 4 en instituciones del Gran Buenos Aires y los 8 restantes en diferentes provincias argentinas (Santa Fé, Chubut, Neuquén y Córdoba). Todos se formaron en universidades públicas y todos, excepto uno, ejercen actualmente en instituciones públicas de salud (hospitales o centros de atención primaria), algunos combinándolo con la práctica en el sector privado","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240248,"idioma_id":4,"titulo":"Chelate route for the synthesis of PbZrxTi1&minus;xO3 thin films","resumen":"A chemical solution deposition route using the chelate approach was developed for the synthesis of PbZrxTi1&#8722;xO3 thin films. The route avoids the highly toxic 2-methoxyethanol used in previous formulations and offers the advantage of a simple and rapid solution synthesis without the need of distillation and refluxing strategies. The use of acetoin as chelating agent allows a transition between amorphous and final perovskite phases with no segregation of secondary phases during film growth. The obtained PbZrxTi1&#8722;xO3 films presented a thickness of &#8764;150 nm and exhibited good dielectric and ferroelectric properties. It was found that rapid thermal annealing facilitates the perovskite formation process and produces films with better ferroelectric properties than those sintered in conventional furnaces.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240249,"idioma_id":5,"titulo":"La Metodología de Actuación Realista como Dispositivo de Atenuación de la Presencia del Actor en Teatro y Cine","resumen":"En el presente trabajo nos proponemos analizar la metodologíade actuación realista como dispositivo de atenuación de la presencia del actor. Consideramosque el sistema Stanislavski constituyó la primera y más acabada resolución técnica a una largaaspiración por la transparencia del enunciado escénico hacia el referente. Para ello, se propuso reducirel carácter disruptivo y acontecimental de la exhibición pública del cuerpo y de la acción del actora través de una serie de procedimientos que analizaremos en este artículo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240250,"idioma_id":4,"titulo":"The Realistic Acting Method as a Mechanism of Attenuation of the Actor?s Presence in Theatre and Cinema","resumen":"We have analyzed the realistic acting methodology as amechanism of attenuation of the actor?s presence. We consider that Stanislavski?s system constitutedthe first technical resolution to an old aspiration for the transparency of the scene toward thereferent. For that, the realistic acting method proposes the reduction of the disruptive nature of thepublic exhibition of the actor?s body and action through a series of procedures that will be analyzedin this paper.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240251,"idioma_id":5,"titulo":"Los talleres de tesis como aproximación a una comunidad de práctica","resumen":"Uno de los desafíos de la formación de investigadores durante los estudios de posgrado es formar en el quehacer de la investigación, que involucra no solamente el desarrollo de competencias sino también la inmersión en una comunidad de práctica, la comunidad académica. Los talleres se constituyen en espacios en los que se establece una interrelación entre teoría y práctica que favorece el aprendizaje del quehacer de la investigación. Este artículo explora los talleres de tesis en una universidad argentina como espacios de aproximación a una comunidad de práctica. Propone un abordaje centrado en los dispositivos pedagógicos, que puede resultar de utilidad para la investigación pedagógico-didáctica sobre la formación de posgrado. Se observaron los encuentros de dos talleres de un mismo programa doctoral en Ciencias Sociales y se realizó un análisis temático. Encontramos que los talleres proponen tareas significativas para la comunidad académica, proveen un ambiente controlado pero no simulado de aprendizaje, favorecen el aprendizaje del repertorio y el intercambio con pares y docentes. Empero, cuando la evaluación es preponderante, el taller propicia lógicas de aprobación más que de aprendizaje. En definitiva, el marco de comunidades de práctica es propicio para el abordaje de la transmisión de saberes prácticos en el marco de la educación de posgrado al no enfocarse solamente en lo que sucede en la institución educativa y tomar al aprendizaje como un proceso que se desarrolla en tanto se participa en una comunidad de práctica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240252,"idioma_id":4,"titulo":"Zonda is a novel early component of the autophagy pathway in Drosophila","resumen":"Autophagy is an evolutionary conserved process by which eukaryotic cells undergo self-digestion of cytoplasmic components. Here we report that a novel Drosophila immunophilin, which we have named Zonda, is critically required for starvation-induced autophagy. We show that Zonda operates at early stages of the process, specifically for Vps34-mediated phosphatidylinositol 3-phosphate (PI3P) deposition. Zonda displays an even distribution under basal conditions and, soon after starvation, nucleates in endoplasmic reticulum-associated foci that colocalize with omegasome markers. Zonda nucleation depends on Atg1, Atg13, and Atg17 but does not require Vps34, Vps15, Atg6, or Atg14. Zonda interacts physically with Atg1 through its kinase domain, as well as with Atg6 and Vps34. We propose that Zonda is an early component of the autophagy cascade necessary for Vps34-dependent PI3P deposition and omegasome formation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240253,"idioma_id":4,"titulo":"Scaling Electrochemical Battery Models for Time-Accelerated and Size-Scaled Experiments on Test-Benches","resumen":"This article presents a dimensional-analysis supported scaling procedure applied to a mathematical model of electrochemical batteries. The main objective of this research is to allow for laboratory size-scaled and time-compressed experimental analysis of processes involving large physical magnitudes and evolving over long time spans. These situations are of interest when considering the sizing of battery packs and other components of energy systems, particularly smart grids, and further systems where battery storage is relevant, like hybrid vehicles and other standalone systems, as well as deciding management strategies on them. Voltage-, current- and time-scaled models preserving the dynamic evolution of a group of relevant physical magnitudes are presented. These models have been validated through simulation and physical experiments on a test-bench designed and constructed on purpose. The physical implementation of the scaled models is not possible in the cases where some of the scaled model parameters cannot be met using real batteries. But, as the mathematical construction of the scaled models is always possible, this problem can be circumvented with a Hardware-in-the-loop approach: the scaled battery is numerically emulated on a programmable and controllable power source\/sink system, which is run in real-time embedded in the test-bench representing the whole system under study.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240255,"idioma_id":4,"titulo":"In vitro RU genotoxic effect on lymphocytes from C. villosus (Xenarthra, Mammalia)","resumen":"In Argentina, Chaetophractus villosus inhabits a wide geographic region that overlaps with agricultural areas where soybean crops. These areas are affected by the application of pesticides. We cultured C. villosus?s blood lymphocyte of individuals of  both sexes and analyzed Roundup full II® formulation (RU, 66.2% glyphosate), testing the concentration of 280, 420, 560, 1120 &#956;mol\/L of active ingredient (glyphosate) diluted in culture media and only culture media used as negative control. Mitomycin C (MMC) was used as positive control. To characterize potential genetic damage we used genotoxic biomarkers as chromosomal aberrations (CA), sister chromatid exchange (SCE) and cell proliferation kinetics (CPK).  Chromatid breaks were the only DNA damage observed. CA and SCE presented statistically significant increase (p &lt; 0.0001) with respect the negative control in all the RU concentrations assessed. CA at 560 &#956;mol\/L RU and MMC were significantly higher than 280 and 420 &#956;mol\/L RU. SCE values at 280 &#956;mol\/L RU and MMC presented statistically significant increase than 420 and 560 &#956;mol\/L RU. All RU concentrations tested caused a statistically significant reduction in the replication index (RI) (p &lt; 0.0001) and at 1120 &#956;mol\/L RU no cells were found. Thus, under these experimental conditions, the biomarkers used evidenced the genotoxic effects of RU on C. villosus?s lymphocyte culture confirming that in vitro RU exposition produces DNA damage in C. villosus.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240256,"idioma_id":4,"titulo":"Colletotrichum sp.- mediated synthesis of sulphur and aluminium oxide nanoparticles and its in vitro activity against selected food-borne pathogens","resumen":"Food spoilage is a major issue globally and million of people suffer from food-borne infections. Hence, there is a need to search for novel and effective antimicrobial agents. Nanoparticles act as antimicrobial agent, which can tackle the problem of food-borne pathogens. The present study includes mycosynthesis of sulphur nanoparticles (SNPs) and aluminium oxide nanoparticles (AlNPs) from Colletotrichum sp. and their characterization by UV-Vis spectroscopy, Nanoparticles Tracking and Analysis, Zeta potential measurement, X-ray diffraction and Transmission Electron Microscopy. Essential oils (EOs) were extracted from the leaves of Eucalyptus globulus and Citrus medica. Nanofunctionalized oils were formulated by combining nanoparticles with EOs. In vitro antimicrobial activity of SNPs, AlNPs, EOs and nanofunctionalized oils was evaluated against selected food-borne pathogens such as Listeria monocytogenes,Salmonella typhi, Chromobacterium violaceum, Fusarium oxysporum and Aspergillus flavus. The antimicrobial activity of SNPs was found to be maximum against Salmonella typhi (21 mm), whereas AlNPs were highly effective against F. oxysporum (22 mm). It was found that activity of antibiotics such as tetracycline, oxytetracycline, gentamicin, fluconazole, ketoconazole, amphoterecin B and nystatin. increase in combination with nanoparticles. Nanofunctionalized oil can be used as a novel antimicrobial agent the prevention of food spoilage caused by food-borne pathogens.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240257,"idioma_id":4,"titulo":"Synergistic antimicrobial potential of essential oils in combination with nanoparticles: Emerging trends and future perspectives","resumen":"The development of resistance to different antimicrobial agents by bacteria, fungi, viruses, parasites, etc. is a great challenge to the medical field for the treatment of infections caused by them, and therefore, there is a pressing need to search for new and novel antimicrobials. The antimicrobial activity of essential oils and biogenic nanoparticles is well known. Recent studies have demonstrated that nanoparticles functionalized with essential oils have significant antimicrobial potential against multidrug- resistant pathogens. The aim of the present review is to discuss various studies on the broad-spectrum antimicrobial activity of essential oils used singly and in combination with nanoparticles. The brief explanation of their mechanism has also been discussed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240258,"idioma_id":4,"titulo":"Quinolines: Microwave-assisted synthesis and their antifungal, anticancer and radical scavenger properties","resumen":"An efficient method for the synthesis of quinolines using microwave irradiation was developed providing 28 quinolines with good yields. The reaction procedures are environmentally friendly, convenient, mild and of easy work-up. Quinolines were evaluated for their antifungal, anticancer and antioxidant propertiesand exhibited high activities in all tests performed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240261,"idioma_id":5,"titulo":"Ruptura de la dormición y exigencias de luz para la germinación de semillas de Juglans nigra","resumen":"Se evaluaron métodos para superar la dormición y determinar las necesidades de luz en la germinación de Juglans nigra. Para superar la latencia y dureza del endocarpio se realizó Estratificación en caliente (T1), Inmersión en ácido giberélico (T2) y Estratifi cación en frío-húmedo (T3). Para la necesidad de luz se evaluó alternancia de oscuridad\/luz y oscuridad permanente. Se analizó el Porcentaje Germinación (% de G), Índice Velocidad de Germinación (IVG), Tiempo Medio Germinación Máxima (TMG), % Plántulas Normales, % Semillas sin germinar, Peso Seco Medio de plántulas (PSM) y el Índice de Germinación Relativo a la luz (GRL). En T1 no hubo germinación y en T2 irrelevante. T3 produjo diferencias altamente signifi cativas en todas las variables analizadas, siendo el período de 4 meses de estratifi cación el mejor para romper la dormición. Al no ser la luz un factor determinante en la germinación, esta especie se clasifi caría como fotoblástica neutra.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240263,"idioma_id":4,"titulo":"EV traction control based on nonlinear observers considering longitudinal and lateral tire forces","resumen":"An observer-based traction control strategy for electric vehicles is proposed in this paper. The proposed strategy considers the combined effects of lateral and longitudinal traction forces, both for acceleration and regenerative braking, even in curved trajectories. Nonlinear reduced-order observers are designed for estimating tire-road friction condition on each traction wheel and vehicle lateral velocity from which side-slip angles are calculated. A detailed analysis of observers convergence is performed, and a method to know the quality of the estimated variables is also proposed. The proposed traction control strategy allows avoiding the traction wheels skidding during acceleration and braking both in straight trajectories and turning maneuvers. The performance of the proposal is verified through simulation on a complete vehicle model, under different situations and even considering a different vehicle tire model.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240264,"idioma_id":4,"titulo":"Excessive weight gain in exclusively breast-fed infants","resumen":"BACKGROUND: Breastfeeding is recommended as the best source of nutrition in the first months of life and observational studies have associated exclusive breastfeeding with decreased weight gain and a protective effect against obesity in childhood. The objective of this study was to describe the characteristics of a cohort of exclusively breastfed obese infants to determine factors that may lead to this unusual weight gain.METHODS: Infants seen between 2003 and 2015 who were exclusively breastfed and showed excessive weight gain in the first year of life were followed with a focus on features of the mother, the child, feeding patterns and the presence of concomitant factors that influence nutritional status. Additionally, in a subset of the sample, macronutrients of the maternal breast milk were analyzed. A descriptive, prospective cross-sectional study was conducted.RESULTS: Of 73 patients, 63% were girls. At 3 months of life, 64% had a weight-for-height standard deviation score (SDS) &gt;2. At 6 and at 12 months, 100% of the patients had a weight-for-height &gt;2 SDS. The mean age at semisolid-food introduction was 7 months. The mean age at weaning was 15.8 months. The babies were fed on demand and no hunger-satiety pattern was observed. In the breast milk samples analyzed, a significantly lower fat content was found.CONCLUSIONS: The results of our study lead to the assumption that inter-individual variations in mother´s milk composition may affect the growth patterns of children.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240265,"idioma_id":4,"titulo":"Sarcoptes scabiei: a reemerging pathogen","resumen":"Human scabies is an infestation of the skin by a mitecalled Sarcoptes scabiei var. hominis. Scabies is present allaround the world and is prevalent in all age groups, mostlychildren and elderly people. This skin disease presents withsevere itch and a papular rash, especially on the hands, feetand genitalia. Crusted scabies is a severe, highly contagiousform of classic scabies. Delayed diagnosis and inadequatetreatment can lead to worsening of the disease. Thepresumptive diagnosis is clinical and is confirmed by thevisualization of the parasite, eggs or feces. Treatmentincludes topic therapy with permethrin or ivermectin, andsystemic therapy with oral ivermectin. There are not manystatistical reports about scabies. In Argentina, there are fewcase reports in the literature, but, nevertheless, scabies maybe more common than reported. This article reportsdifferent aspects of the diagnosis, treatment and prophylaxisof the human itch mite.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240266,"idioma_id":4,"titulo":"The fractal organization of ultradian rhythms in avian behavior","resumen":"Living systems exhibit non-randomly organized biochemical, physiological, and behavioral processes that follow distinctive patterns. In particular, animal behavior displays both fractal dynamics and periodic rhythms yet the relationship between these two dynamic regimens remain unexplored. Herein we studied locomotor time series of visually isolated Japanese quails sampled every 0.5&#8201;s during 6.5 days (&gt;106 data points). These high-resolution, week-long, time series enabled simultaneous evaluation of ultradian rhythms as well as fractal organization according to six different analytical methods that included Power Spectrum, Enright, Empirical Mode Decomposition, Wavelet, and Detrended Fluctuation analyses. Time series analyses showed that all birds exhibit circadian rhythms. Although interindividual differences were detected, animals presented ultradian behavioral rhythms of 12, 8, 6, 4.8, 4&#8201;h and\/or lower and, irrespective of visual isolation, synchronization between these ultradian rhythms was observed. Moreover, all birds presented similar overall fractal dynamics (for scales ¡­30&#8201;s to &gt;4.4&#8201;h). This is the first demonstration that avian behavior presents fractal organization that predominates at shorter time scales and coexists with synchronized ultradian rhythms. This chronobiological pattern is advantageous for keeping the organism?s endogenous rhythms in phase with internal and environmental periodicities, notably the feeding, light-dark and sleep-wake cycles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240267,"idioma_id":4,"titulo":"Short social interactions in male Japanese Quail fail to influence temporal dynamics of testicular and adrenocortical activities irrespective of photoperiodic reproductive status","resumen":"This study evaluates whether short daily maleconspecific visits influence the dynamics of endocrine testicular and adrenal photo-responsiveness. A group of male Japanese Quail was exposed to short photoperiods and another group to long photoperiods. The quail exposedto short photoperiods were classified as responsive (SD-R) or non-responsive (SD-NR), depending on whether or not they lost their reproductive condition after 5 weeks of shortdays (SD). Individuals kept on a long photoperiod were used as controls (LD). After photoperiodic classification and during four consecutive days, individually-caged SDR,SD-NR and LD resident male quail received 5-min visits from photo-stimulated (and therefore sexually active) male quail (social treatment). Cloacal gland volume (CGV), andandrogen and corticosterone metabolites (AM and CM, respectively) in droppings were measured bi-weekly and evaluated by repeated measures ANOVA over a 6-week period. Immediately after photoperiodic classification and before social treatment, CGV, AM and CM values showed a SD-RSD-NRLD pattern (P.001). Along SD exposure, SD-NR quail showed spontaneous cloacal gland recovery and AM and CM concentrations were found to be similar to those of the LD quail. At the end of the study, the SD-R group had still not recovered LD control values. Although the social treatment induced an overall main effect on AM (P.02) and CM concentrations (P.009), these changes were not related to a particular photoperiodic treatment. These findings provide a novel insight into the social modulation of reproductive and adrenocortical responses, particularly during transition from the photosensitive state to photorefractoriness.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240268,"idioma_id":4,"titulo":"Human cystic and alveolar echinococcosis","resumen":"Echinococcus granulosus causes human cystic echinococcosis, whereas Echinococcus multilocularis produces human alveolar echinococcosis. The latter constitutes a slowly progressive but often fatal disease. Cystic echinococcosis is widely distributed and represents a serious problem in sheep- and cattle-raising areas. Eggs released from gravid proglottids in faeces from definitive hosts may contaminate water, fruits, or weeds, and be eaten by humans or other intermediate hosts where a hydatid cyst develops. Histopathological and microscopic examinations, imaging techniques and serologic tests as well as molecular studies are used in diagnosis. Whenever possible, hydatid cysts should be removed surgically, taking precaution to avoid rupture that could lead to seeding, metastatic proliferation and anaphylactic shock. In cases when surgery is not possible, chemotherapy with albendazole or, alternatively, mebendazole combined with praziquantel is used. The close contact with infected dogs is a risk factor for humans. Prevention includes eliminating infection in definitive hosts?especially domestic dogs?by periodic deworming and preventing them from consuming raw entrails from butchered animals. Introduction of vaccines in sheep has been successful as it remarkably diminishes hydatid cysts, with regard to number and size. However, in spite of the different measures taken, the continuous report of cases in endemic countries shows that those measures are insufficient. Widespread vaccine administration to domestic animals acting as intermediary hosts shows promise in achieving a long-term disease prevention and control. In conclusion, current interventions need to be sustained and combined with effective vaccines.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240269,"idioma_id":4,"titulo":"Evaluation of thermophysical properties of (Np,Pu)O 2 using molecular dynamics simulations","resumen":"Molecular dynamics simulations were performed in order to obtain thermophysical properties of the solid solution of (NpxPu1&#8722;x)O2 MOX for the concentrations x&nbsp;=&nbsp;0.0, 0.2, 0.5, 0.8 and 1.0. Lattice parameter, linear thermal expansion coefficient, enthalpy increment and specific heat at constant pressure were evaluated in the temperature range from 300&nbsp;K to 3400&nbsp;K using the NPT ensemble. Elastic constants C11, C12 and C44 were obtained at T&nbsp;=&nbsp;0&nbsp;K whereas the bulk modulus was studied in the whole temperature range from 0&nbsp;K to 3400&nbsp;K. It was found that most of the evaluated magnitudes closely follow a Vegard´s-like law for temperatures below 2000 K. At that point the superionic transition was observed. The results obtained in this work show a good agreement with the available reference data.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240273,"idioma_id":4,"titulo":"Influence of packing density and water film thickness on early-age properties of cement pasteswith limestone filler and metakaolin","resumen":"Supplementary cementitious materials (SCMs) affect the packing density and water film thickness (WFT) of blended cement paste. Herein, the effects of limestone filler (LF) and metakaolin (MK) on the packing density, WFT, flowability, heat of hydration, setting time and compressive strength of blended cement paste were studied. It was found that the addition of LF and MK would increase the packing density but whether it would increase the WFT is dependent on the change in solid surface area. Moreover, dispersion caused by finer particles stimulates the early hydration and reduces the setting time for the same SP dosage. However, the early compressive strength depends on the stimulation and dilution effects of SCM and retarding effect of SP.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240274,"idioma_id":4,"titulo":"Portland blended cements: Demolition ceramic waste management","resumen":"Demolition ceramic wastes (DCWs) wereinvestigated in orderto determine their potential use as supplementarycementitious materials inPortland Blended Cements (PBCs). For this purpose,three ceramic wastes wereinvestigated. After characterization of the materialsused, the effect ofceramic waste replacement (8, 24 and 40% by mass) was analyzed.Pozzolanicactivity, hydration progress, workability and compressive strengthweredetermined at 2, 7 and 28 days. The results showed that the ground wastesbehaveas filler at an early age, but as hydration progresses, the pozzolanicactivityof ceramic waste contributes to the strength requirement.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240275,"idioma_id":4,"titulo":"Blended Cements with Limestone Filler and Kaolinitic Calcined Clay: Filler and Pozzolanic Effects","resumen":"In this paper, binary and ternary blended cements (BC) based on calcined clay (CC, 0?30%) obtained from low-grade kaoliniticclay and limestone filler (LF, 0?10%) were developed and the interaction between the filler effect and pozzolanic effect on the compressivestrength, hydration phases, and pore-size distribution were studied. Results show that early compressive strength decreases for high levelsof replacement (10LF30CC) because of a dilution effect that cannot be compensated for by the filler and pozzolanic effects. Based oncalcium hydroxide (CH) content, the addition of limestone filler in ternary blended cements is favorable to the development of pozzolanicreaction of calcined clay at an early age. This study shows that dilution, filler, and pozzolanic effects are relevant at 2 days, filler andpozzolanic effects are important at 7 days, and the pozzolanic effect is the most important at a later age.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240276,"idioma_id":4,"titulo":"Pozzolanic activity of calcined halloysite-rich kaolinitic clays","resumen":"The aim of this study is to determine the pozzolanic activity of clays with high content of halloysite\/kaolinite, and to evaluate the influence of halloysite\/kaolinite ratio and halloysite morphology in the development of pozzolanic activity of the calcined clays. For this purpose, three different natural clays from Río Negro Province, Argentine, were selected and completely characterized. After calcined at 700 °C and ground to 80% of particle size < 45 &#956;m, pozzolanic activity was determined using the electrical conductivity test, the Frattini test and the compressive strength index. Results show that all calcined clays are classified as high reactive pozzolana. The presence of kaolinite and spheroidal halloysite exerts great influence at early ages; while tubular halloysite has greater influence in the pozzolanic activity and the compressive strength of mortars at later ages.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240278,"idioma_id":5,"titulo":"COMPORTAMIENTO FÍSICO - MECÁNICO SOBRE MEZCLAS CEMENTÍCEAS CON INCORPORACIÓN DE BLOQUE CERÁMICO","resumen":"Se analiza el comportamiento de morteros y hormigones con Bloque Cerámico como reemplazo del cemento portland (8, 24 y 40% en peso). En los morteros se estudió la fluidez, la resistencia a flexión y a compresión y la porosidad; para los hormigones se determinó la resistencia a compresión y a tracción por compresión diametral y la succión capilar. Todos los ensayos se realizaron a 2, 7 y 28 días. Los resultados muestran que a medida que aumenta el porcentaje de reemplazo de residuo cerámico, la fluidez y la resistencia mecánica de los morteros disminuye, mientras que la porosidad aumenta. Por su parte en los hormigones, la resistencia mecánica decrece con el incremento del porcentaje de reemplazo y la succión capilar aumenta","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240279,"idioma_id":4,"titulo":"Colonization in North American Arid Lands: The Journey of Agarito (Berberis trifoliolata) Revealed by Multilocus Molecular Data and Packrat Midden Fossil Remains","resumen":"Here we conduct research to understand the evolutionary history of a shrubby species known as Agarito (Berberis trifoliolata), an endemic species to the Chihuahuan Desert. We identify genetic signatures based on plastid DNA and AFLP markers and perform niche modelling and spatial connectivity analyses as well as niche modelling based on records in packrats to elucidate whether orogenic events such as mountain range uplift in the Miocene or the contraction\/expansion dynamics of vegetation in response to climate oscillations in the Pliocene\/Pleistocene had an effect on evolutionary processes in Agarito. Our results of current niche modelling and palaeomodelling showed that the area currently occupied by Berberis trifoliolata is substantially larger than it was during the Last Interglacial period and the Last Glacial Maximum. Agarito was probably confined to small areas in the Northeastern and gradually expanded its distribution just after the Last Glacial Maximum when the weather in the Chihuahuan Desert and adjacent regions became progressively warmer and drier. The most contracted range was predicted for the Interglacial period. Populations remained in stable areas during the Last Glacial Maximum and expanded at the beginning of the Holocene. Most genetic variation occured in populations from the Sierra Madre Oriental. Two groups of haplotypes were identified: the Mexican Plateau populations and certain Northeastern populations. Haplogroups were spatially connected during the Last Glacial Maximum and separated during interglacial periods. The most important prediction of packrat middens palaeomodelling lies in the Mexican Plateau, a finding congruent with current and past niche modelling predictions for agarito and genetic results. Our results corroborate that these climate changes in the Pliocene\/Pleistocene affected the evolutionary history of agarito. The journey of agarito in the Chihuahuan Desert has been dynamic, expanding and contracting its distribution range and currently occupying the largest area in its history.Published: February 1, 2017Angulo DF, Amarilla LD, Anton AM, Sosa V. 2017. Colonization in North American Arid Lands: The Journey of Agarito (Berberis trifoliolata) Revealed by Multilocus Molecular Data and Packrat Midden Fossil Remains. PLoS ONE 12(2): e0168933. doi:10.1371\/journal.pone.0168933.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240280,"idioma_id":4,"titulo":"Phenotypic variation in arid and semi-arid zones of southern South America: the case of Senna series Aphyllae (Fabaceae, Caesalpinioideae)","resumen":"Senna series Aphyllae includes xeromorphic shrubs and subshrubs that occur in three different biogeographic subregions in arid and semi-arid habitats of southern South America. The series provides a good opportunity to under-stand better the relationship among geographical, climatic, and morphological variation in different taxa. Moreover, in this group the specific and varietal delimitation is still problematic due to the high morphological variation within and among taxa. Statistical analyses of climatic and morphological data and geographical distribution were used to understand the patterns of morphological variation among 394 individuals and to clarify the taxonomic delimitation of entities that belong to series Aphyllae. Senna acanthoclada and S.nudicaulis were segregated from each other and from the remaining taxa; the three recognized varieties of the S.aphylla complex were delimited; S.spiniflorawas well-delimited and S.crassiramea and S.rigidicaulis were overlapping; S.pachyrrhiza was not differentiated from S.aphylla. Ecological niche modelling showed several areas of contact and a large overlap of suitable conditions for several species. The results of this work revealed that most morphological variability is associated with different environmental conditions. This phenotypic plasticity may be caused by the presence of different environments with climatic factors in the South American Transition Zone, Chaco, and northern region of Central Patagonia province","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240282,"idioma_id":4,"titulo":"Glucagon-like peptide 2 prevents down-regulation of intestinal multidrug resistance-associated protein 2 and P -glycoprotein in endotoxemic rats","resumen":"Multidrug resistance-associated protein 2 (Mrp2, ABCC2) and P-glycoprotein (P-gp, ABCB1) constitute essential components of the intestinal biochemical barrier that prevent incorporation of food contaminants, drugs or toxic metabolites into the blood stream. Endotoxemia induced in rats by administration of bacterial lipopolysaccharide (LPS) results in elevated intestinal permeability and toxicity of xenobiotics in part associated with down-regulation of expression and activity of Mrp2 and P-gp. We evaluated the protective effect of glucagon-like peptide 2 (GLP-2), a peptide hormone with enterotrophic properties, on Mrp2 and P-gp alterations induced by single i.p. injection of LPS (5mg\/kg b.wt.) to rats. Two different protocols of GLP-2 administration, namely prevention and reversion, were examined. The prevention protocol consisted of 7s.c. injections of GLP-2 (125&#956;g\/kg b.wt.) administered every 12h, starting 60h before LPS administration. The reversion protocol consisted of 2 doses of GLP-2, starting 3h after LPS injection. Intestinal samples were collected 24h after LPS administration and expression (protein and mRNA) and activity of Mrp2 were evaluated in proximal jejunum whereas those of P-gp were studied in ileum. GLP-2 completely neutralized down-regulation of expression of Mrp2 and P-gp and loss of their respective activities induced by LPS under prevention protocol. GLP-2 was also able to prevent internalization of both transporters from the apical membrane of the enterocyte to intracellular compartments, as detected by confocal microscopy. LPS induced an increase in IL-1&#946; and oxidized glutathione tissue levels, which were also counterbalanced by GLP-2 administration. In contrast, the reversion protocol failed to attenuate Mrp2 and P-gp down-regulation induced by LPS. We conclude that GLP-2 can prevent down-regulation of intestinal expression and activity of Mrp2 and P-gp in endotoxemic rats and that IL-1&#946; and oxidative stress constitute potential targets of GLP-2 protective effects.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240285,"idioma_id":5,"titulo":"ACCESO A LA EDUCACIÓN SUPERIOR MEDIADO POR TIC´S: EL CASO DE LA UNIDAD ACADÉMICA SAN JULIÁN DE LA UNPA EN SANTA CRUZ, ARGENTINA.","resumen":"La Universidad Nacional de la Patagonia Austral (UNPA) es una de las tres universidades nacionales de más reciente creación en Patagonia (luego vinieron Río Negro y Tierra del Fuego). No es objeto de discusión la ampliación de oportunidades en el acceso a la educación superior que ello supuso. Sin embargo, más recientemente, la transformación de la modalidad de enseñanza de presencial a virtual valiéndose de las Tecnologías de la Información y la Comunicación (TIC´s), visualizadas como ?democratización de la educación superior?, ha permitido multiplicar el número de inscriptos pero no (en términos porcentuales y a la fecha de cierre del análisis) el de egresados. En el artículo, a partir de cuantificar los diversos comportamientos, se procura dimensionar el impacto que sobre el comportamiento de la matrícula ha tenido la implementación de un modelo de Educación a Distancia sustentado en el empleo de las TIC´s (trasladando todo el proceso educativo a la mediación tecnológica en la plataforma virtual), que ha venido a suplantar la modalidad presencial (que podríamos denominar como ?tradicional?, en el sentido de que conserva los rasgos centrales de una escolaridad de cursado cotidiano en el ámbito físico de la universidad).La metodología de indagación aquí utilizada es cuantitativa y se observan las carreras de educación de una de las Unidades Académicas de la UNPA. Las tablas permiten avanzar en el objetivo de caracterizar la dinámica de la matrícula mientras el cursado fue presencial y luego, cuando se pasó a la modalidad virtual, procurando comprender las trayectorias académicas desarrolladas por los estudiantes y el impacto que el cambio de modalidad pudo haber tenido en las mismas. Como corolario, exponemos reflexiones que pueden ser útiles para seguir pensando el impacto de las TICs en la educación superior.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240286,"idioma_id":5,"titulo":"Notas para una historia de las ideas en el periodismo. Una propuesta de trabajo a partir de la determinación de vacancias e insuficiencias","resumen":"Este trabajo es un esbozo de constitución de una Historia de las Ideas en el Periodismo como línea que parte de los intereses genuinos de este oficio como singularidad al interior de los estudios sobre comunicación.Para ello se considera que el abordaje del periodismo como subdisciplina adolece de insuficiencias y presenta campos de vacancias que derivan de la excesiva dependencia a categorías y miradas de otras disciplinas desde donde se ha trabajado este objeto de estudio; dada la ausencia de modelos teóricos y metodológicos específicos.Aquí se instala nuestra propuesta, con un enfoque que no busca la construcción de cronologías en torno a medios, sino que analiza cómo las estructuras de pensamiento y la cosmovisión de determinados sujetos influyeron en su ejercicio del periodismo, para determinar que aportes realizaron tanto a la práctica como a la reflexión sobre esta actividad.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240287,"idioma_id":4,"titulo":"Resistance of phages lytic to pathogenic Escherichia coli to sanitisers used by the food industry and in home settings","resumen":"Phages are potentially useful as antimicrobial agents in food-processing environments, provided they can remain active upon extended storage and in the presence of sanitisers. Survival of six phages lytic againstenteropathogenic (EPEC) and shiga-toxigenic (STEC) Escherichia coli strains was assessed upon storage at 4 °C, 20 °C and 70 °C in phosphate-buffered-saline (PBS) and Tris-magnesium-gelatine buffer (TMG) for up to 1 year. The phages were also exposed to ethanol, sodium hypochlorite, peracetic acid, quaternary ammonium chloride (biocide A), hydrogen peroxide\/peracetic acid\/peroctanoic acid (biocide B), p-toluensulfonchloroamide (biocide D) and alkaline chloride foam (biocide C). Plaque-forming units remained unchanged when the phages were stored at 4 °C in both buffers tested, but decreased by 3.5 and 5.7 log10 PFU when stored in PBS at 20 and 70 °C, respectively. Moreover, TMG seems to be the most protective suspension medium with decreasing temperature because a 1log10 PFU reduction was observed at 20 and 70 °C. Incubation in 100% ethanol for 24 h reduced plaque counts only by 2.5 log10 PFU. In 10 ppm of sodium hypochlorite and in biocide B (0.13%), the counts decreased by ~5 and ~6 log10 PFU after15 min. Finally, biocide A and D reduced counts by 4 and 2?4 log10 PFU after 30 min and 8 h of incubation, respectively. Phages were completely inactivated only by peracetic acid and biocides C and E. Therefore, the phages evaluated might be potentially applied together with classical sanitisers such as ethanol andindustrial biocides A, B and D, in disinfection programs against pathogenic STEC and EPEC strains.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240303,"idioma_id":4,"titulo":"Floral nectaries of Koelreuteria elegans subsp. formosana (Sapindaceae): structural, ultrastructural and nectar secretion","resumen":"The structure and ultrastructure of the floral nectary of staminate and pistillate flowers of Koelreuteria elegans subsp. formosana (Sapindaceae, Koelreuterieae) were studied. In both floral morphs, the floral nectary is extrastaminal, receptacular, thimble-shaped and persistent. The anatomical analysis revealed a differentiated secretory parenchyma and a less developed, inner non-secretory parenchyma. These anatomical features reveal that the nectary is structured, and is supplied by phloem traces derived fromthe central stele. In the middle of the floral nectary there are few modified stomata. The nectarostomata were of anomocytic type; they may occur at the level of or sunken below the adjacent epidermal cells. Statistically significant differences were observed between both floral morphs in relation to nectar volume and the different moments of day, whereas the sugar concentration showed no significant differences. Ultrastructural studies showed no difference between staminate and pistillate flowers. At anthesis, amyloplasts and lipid globules were observed in the secretory parenchyma cells, whereas at post-anthesis thesecretory parenchyma cells were degenerated. Floral nectar is secreted through nectarostomata and the outer epidermal cell walls. These results are discussed in relation to other species belonging to different tribes within Sapindaceae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240304,"idioma_id":4,"titulo":"Pollen morphology in selected species of Caricaceae with special reference to novel  palynological characters","resumen":"The pollen grain morphology of Jacaratia corumbensis Kuntze, J. spinosa (Aubl.)A.DC., Vasconcellea quercifolia A. St.-Hil., and Carica papaya L. from Argentine samples were examined for the first time, using light and scanning electron microscopes. Observations and measurements were performed on acetolyzed pollen grains. Principal-components analysis was performed for quantitative morphological variables. Pollen grains were tri-colporate with lalongate endoaperture, oblate spheroidal to prolate, medium, exine bireticulate or reticulate, with granulate lumina. Fastigium was present. Novel palynological data in this study for species identification revealed the presence of margo in C. papaya and variations in endoaperture shapes in all the species. The endoaperture ends often were H-shaped or horn-shaped. The biplot showed a clear separation of the four taxa based on the palynological traits. V. quercifolia was strongly correlated with equatorial diameter, equatorial diameter in polar view, exine thickness, and polar diameter, whereas J. corumbensis and J. spinosa were positively correlated with polar index and polar area index, respectively. The distance between two colpi allowed the discrimination of C.papaya. We confirmed the homogenous nature for most of the qualitative palynological characters in Caricaceae, and demonstrated that pollen morphology in combination with statistical analyses is a reliable tool for delimiting taxonomic groups.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240308,"idioma_id":5,"titulo":"La construcción del yo en Historia de un alma, autobiografía espiritual de Teresa de Lisieux","resumen":"Historia de un alma, de Teresa de Lisieux puede ser ubicada dentro de las especies de la literatura del yo, como autobiografía, un género literario que establece un pacto autobiográfico con el lector basado en la identidad autor-narrador-personaje. Esta afirmación se fundamenta en el presente artículo desde la teoría autobiográfica de Lejeune (1991) y algunas consideraciones de Gusdorf (1991) y Loureiro (1991). En cuanto a su referencialidad, la obra presenta una reelaboración de los sucesos por parte de la autora. Esta reelaboración se manifiesta en las diferentes características de los recuerdos autobiográficos: las evocaciones poseen una fuerte relación con el yo, hay una una estructura narrativa, imágenes visuales y de otras modalidades sensoriales, y un vivo componente emocional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240309,"idioma_id":5,"titulo":"'La Percepción de la Imagen Corporal en la Neurosis y Psicosis'.-","resumen":"'La Percepción de la Imagen Corporal en la Neurosis y Psicosis'.-","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240310,"idioma_id":4,"titulo":"A comparative study of Three-Phase Dual Active Bridge Converters for renewable energy applications","resumen":"The influence of different transformers in the operation of a three-phase dual active bridges DC-DC converter is analyzed. The transformers considered have their windings connected in star-star, delta-delta, star-delta and delta-star. The main objective of this paper is to obtain factors of merits to allow the selection of a transformer which will yield higher converter performance for a given application. These factors of merits allows estimate the losses in power semiconductors and high frequency transformers. Additionally, operation regions under soft switching are deduced for each transformer.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240311,"idioma_id":4,"titulo":").  Specific competences in the Tuning Latin America Project. Their degree of importance and achievement among a sample of psychology students.","resumen":"The implementation of the competence-based education approach at university level is a vehicle for the global transformation of the current Higher Education system. Over the past few decades, psychology has increasingly focused on the identification of core competences in the education of psychologists. The U.S., Canada and Europe have adopted competence-based education approaches. More recently, in 2013 the Tuning Latin America Project introduced the challenge to reach agreement on the education of psychologists in the region. The purpose of this research is to analyse the degree of importance and perceived achievement of the specific competences set out in the Tuning Latin America Project, among a sample of 100 advanced psychology students of a private university in the City of Buenos Aires. For such purpose, the Specific Competences Survey for students of the Tuning Latin America Project was used. All the competences obtained high ratings in terms of importance, in particular those related to professional ethics. In addition, the respondents considered that most of the competences are thoroughly developed during their university training. To conclude, further studies and analyses need to be carried out in order to identify current educational needs for psychologists and thus enhance quality and adjust psychological practice to current social needs.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240312,"idioma_id":5,"titulo":"Valoración de la importancia y logro de las competencias específicas planteadas en el Proyecto","resumen":"El enfoque de formación por competencias ha sido fuertemente promovido porla Unión Europea a partir de la Declaración de Bolonia, lo que dio lugar al desarrollodel Proyecto Tuning para la formación universitaria en Europa, que años más tarde fueadoptado por países de América Latina. La presente investigación tiene como objetivoanalizar el nivel de importancia y logro autopercibido en las competencias específicasplanteadas en el marco del Proyecto Tuning América Latina. Se trabajó con una muestrade 100 graduados pertenecientes a una carrera de psicología de una universidad degestión privada. Se utilizó el Cuestionario de Competencias Específicas del ProyectoTuning América Latina. La media general de importancia fue de M=3.62 y la de logrofue de M=3.27. Todas las competencias fueron valoradas como importantes, y lamayoría de las competencias fueron ampliamente desarrolladas durante la formación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240314,"idioma_id":4,"titulo":"Migration and brackish environment use of Prochilodus lineatus (Characiformes: Prochilodontidae) inferred by Sr:Ca ratio transects of otolith","resumen":"The streaked prochilod, Prochilodus lineatus, represents the most important fishery in the La Plata Basin (South America). Our objective was to analyze brackish environment use by the streaked prochilod captured from Paraná and Uruguay rivers. To accomplish this, lapillus otolith sections were analyzed for Sr:Ca with laser ablation-inductively coupled plasma-mass spectrometry (LA ICP-MS) to infer habitat use of fish. To the interpretation of transects, a threshold that represents the transition between freshwater and brackish environments was calculated using the Sr:Ca ratio of the otolith edge of specimens captured in the first section of the La Plata Estuary (salinity &#8805; 0.5 PSU). The percentage of fish using the estuary was higher in the Paraná (37%) than the Uruguay River (5%). Change-point analysis showed that fish entered the estuary between 1 and 3 times throughout life at a wide range of ages (0-15 years). These incursions had no obvious periodicity. This information should be integrated into future management actions, which should also be specific to each area since migration patterns differ between the major rivers of the basin.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240315,"idioma_id":5,"titulo":"Las dimensiones del bienestar de niños y niñas que viven en Buenos Aires","resumen":"Este trabajo aborda el tema del bienestar, definido como la evaluación cognitiva y afectivaque la persona hace de su propia vida. El interés se centra en entender lo que hace feliz y lo que generabienestar a niños y niñas; y, para lograrlo, se accedió a diferentes áreas de la vida de los\/as niños\/as,intentando abarcar las dimensiones sociales, culturales y políticas del bienestar. Se utilizó el métodocualitativo, dando a niños\/as un papel protagónico. Se trabajó con dos grupos de niños y niñas, entre 8 y12 años de edad que viven en Buenos Aires, Argentina. Se utilizó la técnica de grupo, dándole la palabraa los chicos y, a partir de sus miradas, se focalizó en los siguientes temas: personas significativas en susvidas ? familia y pares ? y lugares significativos ? escuela y ciudad. Los resultados del estudio muestranque la familia y los grupos de pares juegan un papel central para estos niños\/as, mientras que la escuelay la ciudad tienen un lugar ambivalente","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240316,"idioma_id":5,"titulo":"Parasitosis en la población asistida en el HIGA Evita Lanús. Situación actual","resumen":"Las parasitosis continúan siendo un grave problema en la salud pública, puesto que, están estrechamenteasociadas a la edad y al estado de higiene público. Por lo tanto, la incidencia y la prevalencia de parasitosisse han tomado como indicadores del estado de salud de la población en distintos contextos. El objetivo deeste trabajo fue determinar la prevalencia de parasitosis en muestras remitidas a este hospital desde enerode 2015 a junio de 2016, según grupo etario, frecuencia y tipo de parásitos intestinales y no intestinales.Se realizó un estudio retrospectivo en la población asistida en la institución, utilizando los registros de lasmuestras procesadas en el sector de parasitología. De las 413 muestras de materia fecal, 188 resultaronpositivas siendo la prevalencia total de 45,52 %. La distribución por grupo etario fue: 1 - 11 años: 132, 12- 16:18, mayor a 16:38. El tipo y frecuencia de parásitos fue Blastocystis spp.: 95, Giardia lamblia: 53, Enterobiusvermicularis: 45, Dientamoeba fragilis: 23, Entamoeba coli: 14, Ascaris lumbricoides: 11, Endolimaxnana: 8, Entamoeba histolytica \/ dispar: 3, Cryptosporidium spp.: 3, Strongyloides stercoralis: 1. Determinaciónde Ac. anti Toxocara canis \/ cati: 1 - 16 años: Reactivo(R): 17, No Reactivo(NR): 5; Mayor 16: R: 3, NR: 3.El porcentaje de positividad para Ac. antiToxocaracanis\/cati fue de 71,42%. La búsqueda de Trypanosomacruzi resultó negativa en todas las muestras. En una muestra de esputo \/ vómica, se observaron ganchosde Echinococcus spp. Se diagnosticó Larva de Dermatobia hominis en dos ejemplares remitidos. Los datosobtenidos son coincidentes con la bibliografía. Es de destacar la importancia de conocer la sintomatología delos pacientes, sus datos epidemiológicos, estado nutricional e inmunitario, para poder seleccionar el tipo demuestra y conservación adecuada, y aplicar la correcta metodología optimizando así el diagnóstico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240318,"idioma_id":4,"titulo":"Abscisic acid improves cold-tolerance and acclimation in early developmental stages of honey bee","resumen":"The natural composition of nutrients present in food is a key factor determiningthe immune function and stress responses in the honeybee (Apismellifera). We previously demonstrated that a supplement of abscisic acid(ABA), a natural component of nectar, pollen, and honey, increases honeybeecolony survival overwinter. Here we further explored the role of ABAin in vitro-reared larvae exposed to low temperatures. Four-day-old larvae(L4) exposed to 258C for 3 days showed lower survival rates and delayeddevelopment compared to individuals growing at a standard temperature(348C). Cold-stressed larvae maintained higher levels of ABA for longerthan do larvae reared at 348C, suggesting a biological significance forABA. Larvae fed with an ABA-supplemented diet completely prevent thelow survival rate due to cold stress and accelerate adult emergence. ABAmodulates the expression of genes involved in metabolic adjustments andstress responses: Hexamerin 70b, Insulin Receptor Substrate, Vitellogenin, andHeat Shock Proteins 70. AmLANCL2, the honeybee ABA receptor, is also regulatedby cold stress and ABA. These results support a role for ABA increasingthe tolerance of honeybee larvae to low temperatures through priming effects.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240319,"idioma_id":4,"titulo":"Is  Acarapis woodi mite currently infesting Apis mellifera colonies in Argentina?","resumen":"El ácaro traqueal de la abeja de miel Acarapis woodi (Rennie) (Acari: Tarsonemidae) es un parásito interno obligado del sistema respiratorio de las abejas adultas de la miel (Apis mellifera), el cual puede ser uno de los factores que causan la pérdida de colmenas de abejas y la disminución de la industria apícola. En Argentina, el último estudio de prevalencia de A. woodi fue en 1998, por lo que no hay datos actuales sobre la prevalencia e impacto de este a ´caro en colonias de Apis mellifera en este país. Por esta razón, el objetivo de este estudio fue determinar la prevalencia de A. woodi en colmenas de abejas melíferas de apiarios pertenecientes a diferentes regiones geográficas de Argentina (Noroeste, Chaco, Mesopotamia, Pampeana y Patagonia) utilizando dos métodos diferentes de diagnóstico. Un método fue la microscopía tradicional, la cual se basa en la visualizaciónón directa de A. woodi en las tráqueas protorácicas de las abejas, y la otra técnica fue el análisis molecular utilizando PCR en tiempo real con cebadores específicos para amplificar el gen COI de A. woodi. Para realizar el análisis de la prevalencia, las abejas fueron recolectadas durante el invierno, ya que durante esta temporada, las poblaciones de A. woodi son más abundantes en las colonias de abejas. Los resultados fueron negativos para ambos me ´todos diagnóstico, con prevalencia igual al 0%. Considerando que en los últimos años se ha reportado un aumento de la mortalidad en las colmenas de abejas en Argentina, se observa que la acarapisosis no afecta actualmente a la desaparición de las colonias de A. mellifera en Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240320,"idioma_id":4,"titulo":"Morphometric correlation between Apis mellifera morphotypes (hymenoptera) and Varroa destructor (acari) from uruguay","resumen":"Uruguay is characterized by having an Africanization gradient in its honey bee (Apis mellifera) populations from areas bordering Brazil to the most remote locations. Morphological differences have also been found among Varroa destructor populations from different regions. A possible explanation for these morphological changes in mites could be explained by morphological correlations in the host\/parasite A. mellifera\/V. destructor system. The objective of the present study was to identify A. mellifera ecotypes in Uruguay and their correlation with V. destructor populations, using geometric morphometrics analysis. The hypothesis states that there is an Africanization gradient of A. mellifera in the northsoutheastern direction in Uruguay that correlates with morphological variations in V. destructor populations. A morphometrics analysis of six honey bee populations and their respective phoretic mites was carried out by sampling zones that show the gradient in the Uruguayan region. The main results obtained were a morphometric correlation between honey bees and mites. The use of landmarks could be adjusted for the intraspecific differentiation of V. destructor populations, which had not been considered previously. These studies are of major importance to further understand the parasitism caused by V. destructor in honey bees.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240321,"idioma_id":4,"titulo":"Dietary Supplementation of Honey Bee Larvae with Arginine and Abscisic Acid Enhances Nitric Oxide and Granulocyte Immune Responses after Trauma","resumen":"Many biotic and abiotic stressors impact bees? health, acting as immunosupressors and contribute to colony losses. Thus, the importance of studying the immune response of honey bees is central to develop new strategies aiming to enhance bees? fitness to confront the threats affecting them. If a pathogen breaches the physical and chemical barriers, honey bees can protect themselves from infection with cellular and humoral immune responses which represent a second line of defense. Through a series of correlative studies we have previously reported that abscisic acid (ABA) and nitric oxide (NO) share roles in the same immune defenses of Apis mellifera (A. mellifera). Here we show results supporting that the supplementation of bee larvae?s diet reared in vitro with L-Arginine (precursor of NO) or ABA enhanced the immune activation of the granulocytes in response to wounding and lipopolysaccharide (LPS) injection","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240322,"idioma_id":4,"titulo":"Assessing in Vitro Acaricidal Effect and Joint Action of a Binary Mixture Between Essential Oil Compounds (Thymol, Phellandrene, Eucalyptol, Cinnamaldehyde, Myrcene, Carvacrol) Over Ectoparasitic Mite Varroa Destructor (Acari: Varroidae)","resumen":"Varroa destructor (Anderson & Trueman, 2000) causes the most important parasitosis of beekeeping in the world. For this reason, prevention is needed to avoid colony death. The most typical treatments involve synthetic acaricides. However, the use of these aca- ricides results in the emergence of resistant populations of mites to these products and in the appearances of drug residues in products of the hives. Compounds of essential oils have emerged as an alternative to traditional acaricides; however the toxicity produced by these mixtures is currently poorly explored. The aim of this work was to assess, by means of in vitro tests with adult bees, how acaricidal action and toxic interactions in a binary mixture of essential oil compounds (Thymol, Phellandrene, Eucalyptol, Cinna- maldehyde, Myrcene, and Carvacrol) affect V. destructor. Calculations of LC50 ?s of the individual compounds on A. mellifera and V. destructor made clear that the toxic effect of each compound is different for both species. Thymol and Phellandrene turned out to be lethal for mites at lower concentrations than for bees. The binary mixture of these two substances presented a different toxicity than one produced by each pure compound, as it was highly selective for mites in bioassays at 24 hours through complete exposure to both A. mellifera and V. destructor. These results make such formulations optimal sub- stances to be considered as alternative controls for the parasitosis","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240323,"idioma_id":4,"titulo":"Changes in floristic composition and physiognomy are decoupled along elevation gradients in central Argentina","resumen":"Questions: Most vegetation descriptions tacitly assume that floristic compositionand physiognomy are tightly linked. However, the two vegetation propertiesmay not respond in a similar way to environmental and disturbancegradients, leading to uninformed management planning and difficulties whenattempting to restore degraded ecosystems. In this context, we addressed twomain questions: (1) how close are relations between floristic and physiognomictypes as defined by numerical vegetation classification in mountain ecosystems;and (2) how are floristic and physiognomic types distributed along the elevationgradient?Location: Centralmountains of Argentina, between 500 and 1700 ma.s.l.Methods: We selected 437 sites where we performed complete floristic andphysiognomic releves.We classified eight physiognomic and eight floristic types.We tested the relationship between the two classifications through a chi squareanalysis. We tested the association between elevation and each physiognomicand floristic type with randompermutations.Results: In general, floristic types were significantly and positively associatedwithmore than one physiognomic type and vice versa. Physiognomic and floristictypes responded differently to the elevation gradient. Floristic types wererestricted to different sections of the gradient, although having large overlapamong them. In contrast, seven out of the eight physiognomic types did notshow elevation restriction, being distributed along the complete elevation gradient.The open low woodland with shrubs was the only restricted physiognomy,significantly absent fromthe upper part of the gradient.Conclusions: We highlight the importance of considering the two vegetationproperties independently when characterizing vegetation patterns in heterogeneoussystems, since they show decoupled responses to environmental gradients.We note that the assumption of a direct link between floristic compositionand physiognomy may induce bias into the understanding of vegetation patternsand processes. Hence, we encourage managers and restoration practitionersto consider the complete range of possible physiognomic types under eachfloristic type.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240324,"idioma_id":4,"titulo":"Dynamic Building of Software Architectural Connectors View.","resumen":"In this article we present an approach to dynamically validate the usage of software connectors in the context of software architectures. By employing aspect oriented techniques the system execution is monitored in order to obtain an architectural view describing how processes communicate and interact with each other. This output can later be compared to the connectors specied in the architecture document to validate the consistency between the architecture specication and the implementation of the system. Two case studies are presented showing the potential of the approach. We believe the results are promising enough to consider future extensions including other architectural elements beyond connectors.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240327,"idioma_id":4,"titulo":"Combining ecological aspects and local knowledge for the conservation of two native mammals in the Gran Chaco","resumen":"Land use changes in the South American Gran Chaco affect native fauna and the ecosystem services (ES) they provide. The consequences of defaunation and the empty forest syndrome have been identified in tropical and subtropical forests, including the Gran Chaco. Local knowledge regarding native species and the provision of ES can be integrated with scientific research for a better understanding of the system and the consequences of species loss. The aim of this study was to explore whether the Pampas fox (Lycalopex gymnocercus) and the collared peccary (Pecari tajacu) use six distinct natural and modified habitat types available in the arid Chaco, their role as seed dispersers, and the rural community´s perception. We found that the Pampas fox used all habitat types except intensive annual cropland, while the collared peccary used only primary forest within a protected area. Both species exhibited a highly frugivorous diet and were seed dispersers of several native plant species. Interviewees hunted both species; they perceived the Pampas fox as a pest and the collared peccary as a source of food or income. The campesino´s perception and involvement is essential for the conservation of the Chacoan forest and the ES provided.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240329,"idioma_id":4,"titulo":"Characterization of the Preovulatory Period in Dairy Cows","resumen":"The periovulatory period of productive Holstein cows was studied, through their hormone levels,ovarian dynamic, characteristics of the cervical flow and their behavior; observed and registered throughout twoconsecutive periods. Results showed that during ovulation, the most evident changes were: animal behaviour (frombeing restless and unquiet to being quieter and allow to be mounted); the reduction of the size of their vulva togetherwith a loss of the labia turgidity; a decrease in the quantity of flow and this one appeared as a transparent andnoticeable secretion, one which kept the vulva humid and lubricated. The pH of the flow got higher (7-20- 7.50) andthe degree of crystallization was reduced to 1.5-2, among the kinds of estrogenic flow, ovulation coincided with thepresence of certain arrangements corresponding to type S3, P2 and P6. P flow is associated to the time of maximumfertility. The peak of the luteinizing hormone was detected on the ovulation day (1.90mUI\/mL) and 24 hoursafterwards the level was low; estrogens increased on the preovulatory days (0.80-0.97 pg\/mL) causing the sexualbehaviour, the stimulating follicle hormone accompanied the follicular growth and progesterone reached its highestincrease consistent with the establishment of the corpus luteum (1.45ng\/mL). The vulvar characteristics and theanalysis of the cervical flow become complementary tools in order to determine the ideal moment for insemination.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240330,"idioma_id":5,"titulo":"Control de tracción para un vehículo eléctrico basado en observadores no lineales","resumen":"En este trabajo se propone una estrategia de control de tracción para un vehículo eléctrico de cuatro ruedas, basada en observadores no lineales que permiten estimar la fuerza máxima que se puede transferir al suelo. El conocimiento de la fuerza máxima permite realizar un control del deslizamiento de los neumáticos de tracción, evitando que las ruedas patinen aún en superficies de baja adherencia. La estrategia propuesta permite además evitar que se produzca un momento de guiño no deseado en el vehículo cuando las condiciones de suelo a cada lado del mismo son diferentes. Con ello se logra mejorar la eficiencia y el control del vehículo, evitando posibles pérdidas de estabilidad que pueden resultar en riesgos para sus ocupantes. Tanto el observador como el control propuestos son diseñados en base a un modelo dinámico rotacional de la rueda y un modelo de fuerzas de brush. Se presentan resultados de simulación obtenidos empleando un modelo completo de vehículo sobre la plataforma Simulink\/CarSim.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240331,"idioma_id":4,"titulo":"EV traction control based on nonlinear observers considering longitudinal and lateral tire forces","resumen":"An observer-based traction control strategy for electricvehicles is proposed in this work. The proposed strategyconsiders the combined effects of lateral and longitudinal tractionforces, both for acceleration and regenerative braking, even incurved trajectories. Nonlinear reduced-order observers are designedfor estimating tire-road friction condition on each tractionwheel and vehicle lateral velocity, from which side-slip anglesare calculated. A detailed analysis of observers convergence isperformed and a method to know the quality of the estimatedvariables is also proposed. The proposed traction control strategyallows avoiding the traction wheels skidding during accelerationand braking both in straight trajectories and turning maneuvers.The performance of the proposal is verified through simulationon a complete vehicle model, under different situations and evenconsidering a different vehicle tire model.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240332,"idioma_id":5,"titulo":"Herramientas de Diseño para el Desarrollo de Competencias en Educación Básica, Media y Tecnológica: Experiencia en el Instituto Técnico Industrial Pascual Bravo de Colombia","resumen":"La incorporación de las TICS en la educación es cada día más frecuente. Desde herramientas sencillas de comunicación como chat, email y foros, hasta software de simulación, laboratorios virtuales y plataformas de aprendizaje, han logrado junto a diferentes metodologías de enseñanza y sistemas de evaluación más dinámicos y eficientes, desarrollar en los estudiantes competencias que hasta hace pocos años era imposible de desarrollar en las aulas de clase tradicional. En este artículo se presentan los resultados de un proyecto de aula, que consiste en la utilización de software de animación en 3D para promover diferentes competencias, desde las más sencillas como las comunicativas hasta las utilizadas en el mundo laboral. Estas competencias son logradas gracias al trabajo colaborativo y el trabajo por proyectos. En este trabajo, se presentan los resultados logrados con estudiantes de la especialidad de sistemas en el Instituto Técnico Industrial Pascual Bravo de la ciudad de Medellín, Colombia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240333,"idioma_id":5,"titulo":"COMPARACIÓN DE TRES TÉCNICAS EN LA PREPARACIÓN DE NUESTRAS PARA LA CRISTALIZACIÓN DEL FLUJO CÉRVICO EN BOVINOS LECHEROS","resumen":"El objetivo fue comparar tres técnicas de preparación de muestras para cristalización del flujocervical (Impronta por presión, impronta por contacto y frotis), analizando las formas arbóreas(cristalización) como caracterización del flujo cérvico vaginal de bovinos lecheros, según el día decolección y el momento del ciclo estral. Se muestrearon 10 vacas lecheras de la raza HolsteinFriesian multíparas, clínicamente sanas y entre 30 a 50 días post parto. A cada una de ellas se lerecolectó el flujo cérvico vaginal utilizando una pipeta descartable y una jeringa de 50 cc. Las dosimprontas y el frotis fueron preparadas sobre laminas porta objetos, con protocolo de dos pasossegún la metodología de Prado et al. (2012). Preparada las muestras se dejó secar a medioambiente y se realizó la lectura al microscopio con objetivo de mayor aumento (40X) para observarla formación de los cristales, estos procedimientos se realizaron en 4 diferentes momentos del cicloestral (0, 7, 14, 21 días). Para cuantificar la cristalización se utilizó una escala entre 0 a 4, la cualvaría dependiendo de la formación de cristales típicos a menos formación o ausencia. En el día 0,7, 14, 21, el nivel de cristalización en las tres técnicas tenía diferencia significativa (P<0,05). En eldía 0, el 50% de las muestras procesadas por la impronta por contacto e impronta por presiónpresentaron formación típica frente al 20% que fueron procesadas por la técnica de frotis. En eldía 7, el 80% de las muestras procesadas por impronta por contacto, 90% de la técnica de frotisy 70% de la impronta por presión, presentan cristales atípicos. En el día 14, el 60% de las muestrasprocesadas por la impronta por contacto y 30% y 40% de las muestras procesadas por la técnicade frotis y la impronta por presión, respectivamente, mostraron n formación atípica de cristales. Enel día 21, el 40% de las muestras procesadas por la impronta por contacto y 10% de las muestrasprocesadas por la técnica de frotis y la impronta por presión, presentaron formación típica decristales. Se concluye que las técnicas de preparación de muestras influyen en la cuantificación decristalización de mucus cervical, siendo los más recomendables, la impronta por contacto e improntapor presión.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240335,"idioma_id":5,"titulo":"Cuando los límites importan: Dimensión pública e implicancias sociales del trabajo arqueológico","resumen":"Este trabajo aporta una mirada reflexiva sobre el impacto de una investigación arqueológica en el contexto local donde esta se desarrolla. Se presenta el caso del proyecto de investigación en el paraje El Tonelero de la localidad de Ramallo (Provincia de Buenos Aires, Argentina), donde se iniciaron trabajos de Arqueología histórica en el año 2012 como parte de un proyecto que estudia la guerra del Paraná, desde una perspectiva pluridisciplinar. Se discuten las implicancias de la construcción de una ?dimensión pública? en torno a dicha investigación, con el propósito de indagar el tipo de relaciones que confluyen con los contenidos históricos investigados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240337,"idioma_id":4,"titulo":"The evolution of phenotypic integration: How directional selection reshapes covariation in mice","resumen":"Variation is the basis for evolution, and understanding how variation can evolve is a central question in biology. In complexphenotypes, covariation plays an even more important role, as genetic associations between traits can bias and alter evolutionarychange. Covariation can be shaped by complex interactions between loci, and this genetic architecture can also change duringevolution. In this article, we analyzed mouse lines experimentally selected for changes in size to address the question of howmultivariate covariation changes under directional selection, as well as to identify the consequences of these changes to evolution.Selected lines showed a clear restructuring of covariation in their cranium and, instead of depleting their size variation, these linesincreased their magnitude of integration and the proportion of variation associated with the direction of selection. This result iscompatible with recent theoretical works on the evolution of covariation that take the complexities of genetic architecture intoaccount. This result also contradicts the traditional view of the effects of selection on available covariation and suggests a muchmore complex view of how populations respond to selection.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240342,"idioma_id":4,"titulo":"Degenerate cysteine patterns mediate two redox sensing mechanisms in the papillomavirus E7 oncoprotein","resumen":"Infection with oncogenic human papillomavirus induces deregulation of cellular redox homeostasis. Virus replication and papillomavirus-induced cell transformation require persistent expression of viral oncoproteins E7 and E6 that must retain their functionality in a persistent oxidative environment. Here, we dissected the molecular mechanisms by which E7 oncoprotein can sense and manage the potentially harmful oxidative environment of the papillomavirus-infected cell. The carboxy terminal domain of E7 protein from most of the 79 papillomavirus viral types of alpha genus, which encloses all the tumorigenic viral types, is a cysteine rich domain that contains two classes of cysteines: strictly conserved low reactive Zn+2 binding and degenerate reactive cysteine residues that can sense reactive oxygen species (ROS). Based on experimental data obtained from E7 proteins from the prototypical viral types 16, 18 and 11, we identified a couple of low pKa nucleophilic cysteines that can form a disulfide bridge upon the exposure to ROS and regulate the cytoplasm to nucleus transport. From sequence analysis and phylogenetic reconstruction of redox sensing states we propose that reactive cysteine acquisition through evolution leads to three separate E7s protein families that differ in the ROS sensing mechanism: non ROS-sensitive E7s; ROS-sensitive E7s using only a single or multiple reactive cysteine sensing mechanisms and ROS-sensitive E7s using a reactive-resolutive cysteine couple sensing mechanism.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240343,"idioma_id":4,"titulo":"Chemical characterization and biologic effects of polyphenols from Condalia microphylla Cav","resumen":"Condalia microphylla Cav. (Rhamnaceae), popularly known as ?piquillin?, is widely distributed in Patagonia. The drupes are consumed as fresh fruits by Argentine communities. The aim of this work was to quantify the nutritional value C. microphylla fruit and the phenolic compounds present and to determine the functional antioxidant properties in vitro and in vivo. Composition of individual phenols was determined and rutin was the single principal phenolic compound. The extracts contained in-vitro antioxidant activities and total-phenol contents between 1143±112 to 4633±174 &#956;g gallic-acid equivalents (GAEs)\/100 g dry weight, though no relationship was found between the latter parameter&nbsp; and the antioxidant activity of the extracts. When zebra-fish larvae were exposed to oxidative stress&nbsp; (2.4% v\/v H2O2), a concentration as low as 1.44 &#956;g of GAEs\/ml of piquillin-derived polyphenols inhibited lipid oxidation by up to 40%. Thus, in view of these advantageous functional-food properties and the opportunity to exploit this natural resource, piquillin consumption should be promoted worldwide","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240345,"idioma_id":5,"titulo":"Revalorizar el Saber Ancestral?: una experiencia de extensión con nuestros adultos mayores","resumen":"El Proyecto ?Revalorizar el Saber Ancestral?consistió en recuperar saberes populares relacionados con la tradición de uso yaprovechamiento de plantas con valor aromático y medicinal. Los alumnos ydocentes de la UNRN actuaron como interlocutores entre el conocimiento de losadultos mayores y las nuevas generaciones, quienes ignoran dichos saberes. Enun ámbito de esparcimiento e intercambio, se relevaron testimonios sobre el usode plantas con propiedades curativas o de valor alimenticio. A fin dereivindicar parte de nuestro patrimonio cultural intangible, esos conocimientosfueron compartidos con la comunidad, gracias al efecto multiplicador de losdocentes y alumnos.Esta iniciativa actuó como facilitadora de lacomunicación intergeneracional y entre pares. Se propició un ámbito donde losadultos mayores pudieron ser y sentirse protagonistas de actividades queotorgaron satisfacciones como personas y como ciudadanos. La posibilidad de serel ?adulto mayor?, quien ofrece su saber a los jóvenes, establece un vínculoque los fortalece.&nbsp; Finalmente,destacamos que la reflexión sobre las prácticas extensionistas manifiesta unaimportante función social y constituye un proceso formativo integrador delvínculo universidad-sociedad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240346,"idioma_id":4,"titulo":"An approximation scheme for uncertain minimax optimal control problems.","resumen":"Abstract In this work, we address an uncertain minimax optimal controlproblem with linear dynamics where the objective functional is the expectedvalue of the supremum of the running cost over a time interval. By takingan independently drawn random sample, the expected value function is approximatedby the corresponding sample average function. We study the epiconvergenceof the approximated objective functionals as well as the convergenceof their global minimizers. Then we dene an Euler discretization intime of the sample average problem and prove that the value of the discretetime problem converges to the value of the sample average approximation.In addition, we show that there exists a sequence of discrete problems suchthat the accumulation points of the minimizers are optimal solutions of theoriginal problem. Finally, we propose a convergent descent method to solvethe discrete time problem, and show some preliminary numerical results fortwo simple examples.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240347,"idioma_id":4,"titulo":"Inactivation kinetics of peroxidase and polyphenol oxidase in peach juice treated with gaseous ozone","resumen":"The effectiveness of gaseous ozone for inactivating peroxidase (POD) and polyphenoloxidase (PPO) in peach juice was investigated. The suitability of first-order and Weibull models to describe inactivation kinetics was also analysed. Peach juice was exposed to ozone (0.11 and 0.20 mg O3 min&#8722;1 mL&#8722;1) in a bubble column up to 12 min at 20 ± 1 °C. Enzyme activities were reduced due to treatments. The magnitude of the inactivation increased with ozone level and exposure time. Reductions in activity after 12 min of treatment ranged between 99.5% and 99.8% for POD and between 93.9% and 97.3% for PPO, depending on ozone concentration. Inactivation curves were successfully fitted with the first-order and Weibull models; although, based on the root-mean-square error, the corrected Akaike and the Bayesian Schwarz criterion, the Weibull model showed stronger capability in all cases.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240348,"idioma_id":4,"titulo":"Integrated bio-affinity nano-platform into a microfluidic immunosensor based on monoclonal bispecific trifunctional antibodies for the electrochemical determination of epithelial cancer biomarker","resumen":"Background The epithelial cell adhesion molecule (EpCAM) is a biomarker that is highly overexpressed on the surface of epithelial carcinoma cells. In this study, silver nanoparticles covered with polyvinyl alcohol (AgNPs-PVA) were synthesized, characterized and used in a microfluidic immunosensor based on the use of anti-EpCAM recombinant antibodies as a trapping agent. Methods The concentration of trapped EpCAM is then electrochemically quantified by HRP-conjugated anti-EpCAM-antibody. HRP reacted with its enzymatic substrate in a redox process which resulted in the appearance of a current whose magnitude (at a working voltage as low as &#8722; 0.10 V) is directly proportional to the concentration of EpCAM. Results Under optimized conditions, the detection limits for the microfluidic immunosensor and a commercial ELISA were 0.8 and 13.9 pg\/L, respectively. The within-assay and between-assay coefficients of variation are below 6.5% for the proposed method. The immunosensor was validated by analyzing patient samples, and a good correlation with a commercial ELISA was obtained. Conclusions The good analytical performance is attributed to the efficient immobilization of the anti-EpCAM recombinant antibodies on the AgNPs-PVA, and its high specificity for EpCAM. This microfluidic immunosensor is intended for use in diagnosis and prognosis of epithelial cancer, to monitor the disease, and to assess therapeutic efficacy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240349,"idioma_id":4,"titulo":"Microfluidic immunosensor based on mesoporous silica platform and CMK-3\/poly-acrylamide-co-methacrylate of dihydrolipoic acid modified gold electrode for cancer biomarker detection","resumen":"We report a hybrid glass-poly (dimethylsiloxane) microfluidic immunosensor for epidermal growth factor receptor (EGFR) determination, based on the covalent immobilization of anti-EGFR antibody (anti-EGFR) on amino-functionalized mesoporous silica (AMS) retained in the central channel of a microfluidicdevice. The synthetized AMS was characterized by N2 adsorption-desorption isotherm, scanning electron microscopy (SEM), energy dispersive spectrometry (EDS) and infrared spectroscopy. The cancer biomarker was quantified in human serum samples by a direct sandwich immunoassay measuringthrough a horseradish peroxidase-conjugated anti-EGFR. The enzymatic product was detected at -100 mV by amperometry on a sputtering gold electrode, modified with an ordered mesoporous carbon (CMK-3) in a matrix of poly-acrylamide-co-methacrylate of dihydrolipoic acid (poly(AC-co-MDHLA)) through in situ copolymerization. CMK-3\/poly(AC-co-MDHLA)\/gold was characterized by cyclic voltammetry, EDS and SEM. The measured current was directly proportional to the level of EGFR in human serum samples. The linear range was from 0.01 ng mL-1 to 50 ng mL-1. The detection limit was 3.03 pg mL-1, and the within- and between-assay coefficients of variation were below 5.20%. The microfluidic immunosensor is a very promising device for the diagnosis of several kinds of epithelial origin carcinomas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240350,"idioma_id":4,"titulo":"Fluorescent immunosensor using AP-SNs and QDs for quantitation of IgG anti-Toxocara canis","resumen":"The objective of this work was to develop a microfluidic immunosensor for the quantitative determination of IgG antibodies to Toxocara canis (IgG anti-T. canis), causal agent of toxocariasis. This disease is caused by accidental ingestion of infective eggs that hatch into the first portion of the intestine. Subsequently, the juvenile stages are distributed throughout the body, generating symptoms from mild to severe manifestations. The possibility of early diagnosis is of great importance, allowing proper management and treatment of patients suffering from toxocariasis. IgG anti-T. canis antibodies detection was carried out using a non-competitive immunoassay, in which excretory-secretory antigens from T. canis second-stage larvae (TES) were covalently immobilized on 3-aminopropyl-functionalized silica-nanoparticles (AP-SNs). Antibodies present in serum samples immunologically reacted with TES and then were quantified by using a second antibody labeled with cadmium selenide zinc sulfide quantum dots (CdSe-ZnS QDs). The concentration of IgG anti-T. canis antibodies present in the serum sample was measured by LIF detector, using excitation lambda at 491 nm and emission at 540 nm. The total assay time was 30 min, having made LIF detection in less than 1 min. The detection limit calculated for the proposed methodology was 0.12 ng mL&#8722; 1 and the coefficients of intra- and inter-assay variation were less than 6%. The results show the usefulness of the developed immunosensor for the fast determination of IgG antibodies anti-T. canis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240351,"idioma_id":4,"titulo":"Development of a nanostructured immunosensor for early and in situ detection of Xanthomonas arboricola in agricultural food production","resumen":"We report a microfluidic electrochemical immunosensor for Xanthomonas arboricola (XA) determination, based on the covalently immobilization of monoclonal anti-XA antibody (anti-XA) on a previously amino functionalized SBA-15 in situ synthesized in the central channel of a glass-poly(dimethylsiloxane) microfluidic immunosensor. The synthetized amino-SBA-15 was characterized by N2 adsorption-desorption isotherm, scanning electron microscopy and infrared spectroscopy. XA was detected by a direct sandwich immunoassay through an alkaline phosphatase (AP) enzyme-labeled anti-XA conjugate. Later, the substrate p-aminophenyl phosphate was converted to p-aminophenol by AP. The enzymatic product was detected at +100 mV on a sputtered gold electrode. The measured current was directly proportional to the level of XA in walnut trees samples. The linear range was from 5 × 102 to 1 × 104 CFU mL&#8722;1. The detection limit was 1.5 × 102 CFU mL&#8722;1, and the within- and between-assay coefficients of variation were below 5%. Microfluidic immunosensor is a very promising tool for the early and in situ diagnosis of XA in walnuts avoiding serious economic losses.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240353,"idioma_id":4,"titulo":"The effect of substrate\/inoculum ratio on the kinetics of methane production in swine wastewater anaerobic digestion","resumen":"Methane production from swine wastewater wasevaluated by using sewage sludge as inoculum in three substrate to inoculum ratios (SIRs) named A (1:1), B (3:1) and C(6:1), with the objective to identify the proportion that optimizes the performance of the process. Duplicated batch bioreactors of 1 L capacity under mesophilic conditions were used to carry out the experiment. The highest biogas yield was observed in A treatment (554 ± 75 mL\/g volatile solid (VS). Cumulative methane production decreased from 382 ± 22 to 232 ± 5 mL\/g VS when SIR increased from 1:1 to 6:1. The first-order model and the modified Gompertz equation were used to model the experimental cumulative methane yield giving adjustments with coefficients of determination of 96 and 99% respectively. The effect of the SIRwas analysed based on the kinetic parameters of the Gompertz equation, which are methane production potential, maximum methane production rate and lag-phase time. The best performance in terms of the kinetic parameters was obtained fortreatment A; however, treatment B could still ensure a stable process. The use of higher inoculum concentration generated 463.1% higher methane production rate and required 77.3% shorter adaptation time (lag phase) in the SIR range studied.When higher SIR was used (e.g. 14:1, previous work), it could be observed that the Gompertz equation also adjusted adequately the experimental data (R2> 0.99) although the lag-phase time did not remain in a linear relationship with SIR butexponentially above SIR = 6:1. These results demonstrated that when a low amount of inoculum was used, the adaptation time of microorganisms resulted much higher than expected delaying the methane production and extending the time neededto achieve adequate performance of the process.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240354,"idioma_id":4,"titulo":"Can the extract of Arisolochia argentina Griseb affect foraging activity of the leaf cutting ant Acromyrmex lundi (Guérin)? Preliminary assays","resumen":"The aim of this study was to evaluate whether foraging decisions of Acromyrmex lundi in the &#64257;eld are affected by the extract of Aristolochia argentina. A free choice test was performed using Rosa x hybrida leaves treated with the extract and control with acetone. Two leaves (treated and control) were presented on either side of a foraging trail. The percentage of removed material was recorded for 90 minutes of observation on two consecutive days. Dry weight and repellency index were calculated. Ant activity, the percentage of carried leaves andweight data were analyzed using a ? t ? -test for paired data, and a General Linear Mixed Model test was used to evaluate the different variables and their interactions. A. argentina extract (1%) did not affect the foraging activity of A. lundi, whereas the 5% dose caused signi &#64257; cant differences in foraging activity as well as between the factors and the interactions. A repellencyindex of above 95% was obtained at the 5% dose. The extract of A. argentina could be considered for future management of this insect.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240355,"idioma_id":5,"titulo":"Comparación del uso de red de arrastre comercial vs. rastra en el monitoreo de la fauna acompañante en la pesquería de la vieira patagónica (Zygochlamys patagonica) en Argentina","resumen":"En este estudio se presenta la información sobre la riqueza específica y composición de la comunidad bentónica asociada a la pesquería de vieira patagónica, analizando la información de las campañas exploratorias y de evaluación del recurso entre los años 1995 y 2013 en la zona denominada ?Unidad de Manejo B?. Dicha zona ha sido estudiada y evaluada en el período mencionado por medio de rastras y redes de arrastre de fondo comerciales. Los resultados obtenidos sugieren que el rango de riqueza de especies por estación sería mayor en los años en que las muestras de la comunidad bentónica provinieron de capturas realizadas con la rastra, arte que permitiría estimar mejor la riqueza de especies por sitio, detectando la presencia de un mayor número de especies por muestra y una mejor representación dentro de la comunidad de las especies menos conspicuas y de menor tamaño.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240356,"idioma_id":4,"titulo":"Description of Antho (Plocamia) bremecae sp. nov. and checklist of Microcionidae (Demospongiae: Poecilosclerida) from Burdwood Bank and neighboring areas, SW Atlantic Ocean","resumen":"In this contribution, we describe a new Demospongiae species, Antho (Plocamia) bremeci sp. nov, from the west slope of Burdwood bank, a poorly studied region in the SW Atlantic Ocean. We also recorded for the first time in the region two other microcionid species, Clathria (Axosuberites) nidificata and Clathria (Microciona) antarctica. We also provide a regional checklist of Microcionidae from Burdwood Bank and neighboring areas, including Malvinas (Falkland) Islands and Tierra del Fuego Province.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240357,"idioma_id":5,"titulo":"Comparación del uso de red de arrastre comercial vs. rastra en el monitoreo de la fauna acompañante en la pesquería de la vieira patagónica (Zygochlamys patagonica) en Argentina","resumen":"En este estudio se presenta la información sobre la riqueza específica y composición de la comunidad bentónica asociada a la pesquería de vieira patagónica, analizando la información de las campañas exploratorias y de evaluación del recurso entre los años 1995 y 2013 en la zona denominada ?Unidad de Manejo B?. Dicha zona ha sido estudiada y evaluada en el período mencionado por medio de rastras y redes de arrastre de fondo comerciales. Los resultados obtenidos sugieren que el rango de riqueza de especies por estación sería mayor en los años en que las muestras de la comunidad bentónica provinieron de capturas realizadas con la rastra, arte que permitiría estimar mejor la riqueza de especies por sitio, detectando la presencia de un mayor número de especies por muestra y una mejor representación dentro de la comunidad de las especies menos conspicuas y de menor tamaño.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240358,"idioma_id":4,"titulo":"Description of Antho (Plocamia) bremecae sp. nov. and checklist of Microcionidae (Demospongiae: Poecilosclerida) from Burdwood Bank and neighboring areas, SW Atlantic Ocean","resumen":"In this contribution, we describe a new Demospongiae species, Antho (Plocamia) bremeci sp. nov, from the west slope of Burdwood bank, a poorly studied region in the SW Atlantic Ocean. We also recorded for the first time in the region two other microcionid species, Clathria (Axosuberites) nidificata and Clathria (Microciona) antarctica. We also provide a regional checklist of Microcionidae from Burdwood Bank and neighboring areas, including Malvinas (Falkland) Islands and Tierra del Fuego Province.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240359,"idioma_id":4,"titulo":"Unveiling the submarine landscape of the Namuncurá Marine Protected Area, Burdwood Bank, SW Atlantic Ocean","resumen":"In this contribution we provide the first images of the submarine landscape of the Namuncurá Marine Protected Area, Burdwood Bank, at the SW Atlantic Ocean. This non-invasive approach revealed and offered a complementary view of the seafloor and its fauna, only previously reported from trawl catches.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240360,"idioma_id":5,"titulo":"Comparación del uso de red de arrastre comercial vs. rastra en el monitoreo de la fauna acompañante en la pesquería de la vieira patagónica (Zygochlamys patagonica) en Argentina","resumen":"En este estudio se presenta la información sobre la riqueza específica y composición de la comunidad bentónica asociada a la pesquería de vieira patagónica, analizando la información de las campañas exploratorias y de evaluación del recurso entre los años 1995 y 2013 en la zona denominada ?Unidad de Manejo B?. Dicha zona ha sido estudiada y evaluada en el período mencionado por medio de rastras y redes de arrastre de fondo comerciales. Los resultados obtenidos sugieren que el rango de riqueza de especies por estación sería mayor en los años en que las muestras de la comunidad bentónica provinieron de capturas realizadas con la rastra, arte que permitiría estimar mejor la riqueza de especies por sitio, detectando la presencia de un mayor número de especies por muestra y una mejor representación dentro de la comunidad de las especies menos conspicuas y de menor tamaño.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240361,"idioma_id":4,"titulo":"Description of Antho (Plocamia) bremecae sp. nov. and checklist of Microcionidae (Demospongiae: Poecilosclerida) from Burdwood Bank and neighboring areas, SW Atlantic Ocean","resumen":"In this contribution, we describe a new Demospongiae species, Antho (Plocamia) bremeci sp. nov, from the west slope of Burdwood bank, a poorly studied region in the SW Atlantic Ocean. We also recorded for the first time in the region two other microcionid species, Clathria (Axosuberites) nidificata and Clathria (Microciona) antarctica. We also provide a regional checklist of Microcionidae from Burdwood Bank and neighboring areas, including Malvinas (Falkland) Islands and Tierra del Fuego Province.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240362,"idioma_id":4,"titulo":"Unveiling the submarine landscape of the Namuncurá Marine Protected Area, Burdwood Bank, SW Atlantic Ocean","resumen":"In this contribution we provide the first images of the submarine landscape of the Namuncurá Marine Protected Area, Burdwood Bank, at the SW Atlantic Ocean. This non-invasive approach revealed and offered a complementary view of the seafloor and its fauna, only previously reported from trawl catches.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240366,"idioma_id":5,"titulo":"Enseñar en la universidad pública argentina: Los desafíos del oficio docente en una época de transformaciones.","resumen":"Este trabajo presenta algunos resultados de un proyecto de investigación centrado en explorar los sentidos acerca del conocimiento y su transmisión en relatos de profesores\/as universitarios\/as reconocidos\/as por los estudiantes como referentes en su formación de grado en la Universidad Nacional de Rosario, Argentina. Desde un enfoque biográfico-narrativo se abordan las principales transformaciones y desafíos de la docencia universitaria en las últimas décadas, intentando responder una serie de interrogantes transversales al oficio de enseñar: ¿Cuáles son los saberes específicos de un docente universitario?, ¿dónde se adquieren dichos saberes?, ¿qué operaciones se ponen en juego en la transmisión de saberes y experiencias? Se recuperan trayectorias académicas de los docentes que conducen a ampliar  la mirada sobre la construcción social del proceso de enseñanza.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240367,"idioma_id":5,"titulo":"Reforma policial y profesionalización en seguridad aeroportuaria (2005-2015)","resumen":"La investigación examina el proceso de implementación de la oferta formadora y capacitadora de la Policía de Seguridad Aeroportuaria en Argentina, y sus consecuencias en la profesionalización policial. La metodología de investigación combina el análisis documental, de recursos burocráticos, y entrevistas y encuestas a los actores involucrados sobre los cursos de formación y capacitación de la Policía de Seguridad Aeroportuaria. Los resultados muestran que los reformadores de la ex Policía Aeronáutica Nacional han tenido un alcance limitado en el cumplimiento de sus objetivos en materia de formación, capacitación y profesionalización policial. En las conclusiones se discuten las implicancias de los resultados de esta investigación para el debate más amplio sobre formación y profesionalización policial en este país.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240369,"idioma_id":4,"titulo":"Physicochemical characterization of water-soluble chitosan derivatives with singlet oxygen quenching and antibacterial capabilities","resumen":"New water-soluble chitosan derivatives (WSCh) were obtained by Maillard reaction (MR) between glucosamine (GA) with both low and medium molecular weight chitosans (Ch). The WSCh showed larger solubility than the respective Ch, while their deacetylation degree (DD) decreased by approximately 12%. Infrared spectroscopy experiments of WSCh confirmed the formation of imine bonds after MR with intensified pyranose structure, and sugar molecules as polymer branches. However, a 6-times reduction of the molecular weight of WSCh was measured, indicating the breakdown of the polysaccharide chain during the MR. The polysaccharides quenched singlet molecular oxygen (1O2), with rate quenching constants correlating with the DD value of the samples, suggesting the important role of amino groups (&#8722;NH2) in the deactivation of 1O2. Additionally, all polysaccharides presented antimicrobial activity against pathogenic bacteria, e.g. Staphylococcus aureus, Escherichia coli, Salmonella sp., Enterococcus faecalis and Listeria ivanovii, as tested by their minimum inhibitory concentration (MIC). This way we obtained new water-soluble polysaccharides, with similar functional properties to those presented by native Ch, enhancing its potential application as carrier material for bioactive compounds.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240370,"idioma_id":4,"titulo":"Modeling and robust control of a twin wind turbines structure","resumen":"The control of a new structure of twin wind turbines (TWT) is presented in this paper. This new concept includes two identical wind turbines ridden on the same tower, which can pivot face the wind with no additional actuator. The motion of the arms carrying the TWT is free. The control law based on sliding mode controller is designed to track the maximum power, by controlling the rotor speed of the TWT and the yaw rotation but without yaw actuator. Finally, performances of the proposed control strategy are compared to standard proportional integral controller, for several scenarios (time varying direction or magnitude of the wind, error on the inertia of the system, ...).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240371,"idioma_id":4,"titulo":"Formulation and in-vitro efficacy of antifungal mucoadhesive polymeric matrices for the delivery of miconazole nitrate","resumen":"Oral candidiasis is the most common opportunistic infection affecting patients with the human immunodeficiencyvirus. Miconazole buccal tablets or miconazole gel are approved for the treatment of oropharyngeal candidiasis.However, buccal films present more flexibility and also offer protection for the wounded mucosa,reducing pain. Due to their small size and thickness, buccal films may improve patients´ compliance, comparedto tablets. Additionally, they may increase the relatively short residence time on the mucosa of oral gels, whichare easily removed by saliva. Polymeric films loaded with miconazole nitrate were prepared by a casting\/solventevaporation methodology using chitosan, carbopol, gelatin, gum arabic, and alginate to form the polymeric matrices.The morphology of films was investigated by scanning electron microscopy; interactions between polymerswere analyzed by infrared spectroscopy and drug crystallinity by differential thermal analysis and X-raydiffraction. Films were characterized in terms of thickness, folding endurance, tensile properties, swelling, adhesiveness,and drug release. Finally, the antifungal activity against cultures of the five most important fungal opportunisticpathogens belonging to Candida genus was investigated. The more appropriate formulations werethose based on chitosan-gelatin and chitosan-carbopol which showed good mechanical properties and adhesiveness,a relative low swelling index, improved drug release, and showed better in vitro activity against Candida culturesthan miconazole nitrate raw material. Thus, it will be possible to produce a new pharmaceutical form basedon polymeric films containing chitosan and miconazole nitrate, which could be loaded with low drug concentrationproducing the same therapeutic effect against Candida cultures.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240372,"idioma_id":5,"titulo":"Procesos de validación mediados por el software GeoGebra. Los criterios de congruencia para explorar, construir, argumentar y demostrar","resumen":"El presente trabajo es un estudio que contrasta el análisis a priori de una secuencia didáctica y los registros escrito-visuales y auditivos tomados para afianzar los criterios de congruencia de triángulos en un 1er año de secundaria. En dicha secuencia se propició el uso del software GeoGebra para la resolución de los problemas presentados.En el mismo se muestra la evolución del pensamiento del alumno y de sus esquemas mentales en cuanto al uso del software. Este análisis tomó en cuenta la génesis instrumental de Rabardel (instrumentación-instrumentalización), así como también el esquema de ruta de la demostración de Acosta G (2004). Se desarrolla además el proceso de exploración, construcción, argumentación y demostración de los alumnos; y por último su camino desde la justificación visual hasta la demostración matemática utilizando propiedades geométricas y los criterios de congruencia de triángulos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240373,"idioma_id":4,"titulo":"Lead enhancement of 3T3-L1 fibroblasts differentiation to adipocytes involves ERK, C\/EBP beta and PPAR gamma activation.","resumen":"Lead (Pb) is an environmental and industrial contaminant that still represents a public health problem. Elevated Pb exposure has been inversely correlated with femoral bone density and associated with osteoporosis. In the last years, it has been shown that inhibition of osteogenesis from mesenchymal stem cells activates adipogenesis and vice versa. In this paper, we investigated the effect of Pb on the differentiation of 3T3-L1 fibroblasts to adipocytes which is the cell model most used to study adipogenesis. After induction of differentiation, 2 days post-confluent cells re-enter the cell cycle and undergo mitotic clonal expansion (MCE) followed by expression of genes that produce the adipocyte phenotype. The presence of concentrations of Pb up to 10 &#956;M during differentiation of 3T3-L1 fibroblasts did not interfere with MCE but enhanced the accumulation of cytosolic lipids that occur during adipogenesis, as well as, the induction of PPAR&#947;, the master gene in adipogenesis. It is known that PPAR&#947; upregulation is subsequent to induction of C\/EBP&#946; and ERK activation, which are early events in adipogenesis. We found that both events were enhanced by Pb treatment. Our results support a stimulatory effect of Pb on adipogenesis which involves ERK activation and C\/EBP&#946; upregulation prior to PPAR&#947; and adipogenesis activation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240375,"idioma_id":4,"titulo":"Hypothyroidism decreases JAK\/STAT signaling pathway in lactating rat mammary gland","resumen":"Thyroid pathologies have deleterious effects on lactation. Especially hypothyroidism (HypoT) induces premature mammary involution at the end of lactation and decreases milk production and quality in mid lactation. Milk synthesis is controlled by JAK2\/STAT5 signaling pathway and prolactin (PRL), which activates the pathway. In this work we analyzed the effect of chronic 6-propyl-2- thiouracil (PTU)-induced HypoT on PRL signaling pathway on mammary glands from rats on lactation (L) days 2, 7 and 14. HypoT decreased prolactin receptor expression, and expression and activation of Stat5a\/b protein. Expression of members of the SOCS-CIS family, inhibitors of the JAK-STAT pathway, decreased in L2 and L7, possibly as a compensatory response of the mammary cells to maintain PRL responsiveness. However, on L14, the level of these inhibitors was normal and the transcription of &#945;-lactoalbumin (lalba), a target gene of the PRL pathway, decreased by half. HypoT altered the transcriptional capacity of the cell and decreased mRNA levels of Prlr and Stat5b on L14. Stat5b gene has functional thyroid hormone response elements in the regulatory regions, that bind thyroid hormone receptor &#946; (TR&#946;) differentially and in a thyroid hormone dependent manner. The overall decrease in the PRL signaling pathway and consequently in target gene (lalba) mRNA transcription explain the profound negative impact of HypoT on mammary function through lactation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240376,"idioma_id":4,"titulo":"EVALUATION OF CYTOTOXIC AND ANTITUMORAL PROPERTIES OF TESSARIA ABSINTHIOIDES (HOOK & ARN) DC, ?PÁJARO BOBO?, AQUEOUS EXTRACT","resumen":"Higher plants have provided various natural derived drugs used currently in western medicine.essaria absinthioides (Hook. & Arn.) DC, Asteraceae, is a native plant from South-America with reported ethnopharmacological and culinary uses. Despite recent scientific reports about plants properties, there is not a well conducted research about its anticancer and potential toxic effects. The current work demonstrates the plant aqueous extract composition; the in vitro induced cytotoxicity, and explores, in vivo, its oral toxicity and antitumoral effects. Composition of aqueous extract was determined by phytochemical reactions. Cytotoxicity was tested in tumoral (Hela, Gli-37, HCT-116 and MCF-7) and non-tumoral (HBL-100) cells, using MTT assay. Oral toxicity and the antitumor activity against colorectal carcinoma were studied in rodents. The chemical analysis revealed the presence of flavonoids, carbohydrates, sterols, terpenes and tannins. Cytotoxicity towards tumoral cells was observed (CV50: 3.0 to 14.8 &#956;g\/ml); while in non-tumoral cells, extracts evidence a selective reduced toxicity (CV50: 29.5 &#956;g\/ml). Oral administration of the extract does not induce acute nor dose-repeated toxicity at doses up to 2000 mg\/kg and 1000 mg\/kg\/day, respectively. The antitumoral effect was confirmed by a significant increase in a median survival from 24 weeks (non-treated) to 30 weeks (T. absinthioides treated). The present data indicate that T. absinthioides extract exhibits cytotoxicity against cancer cell lines, with no-toxic effects and significant antitumoral effects in colorectal cancer when is orally administrated. In conclusion, T. absinthioides possesses selective cytotoxicity and antitumoral activities, making its plant derivatives products promising for cancer research and treatment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240387,"idioma_id":5,"titulo":"Evaluación de la cantidad y calidad nutricional de alfajores dietéticos de bajo valor glucídico, disponibles en el mercado de la ciudad de Rosario, Argentina","resumen":"Introducción: El alfajor es uno de los productos más activo del mercado de las golosinas y se encuentra en la alimentación cotidiana de la población Argentina, existiendo modificados para personas con diversas patologías, como es el caso de los alfajores dietéticos de bajo valor glucídico. Objetivo: Evaluar, a través del rotulado nutricional, la cantidad de grasas totales, ácidos grasos saturados (AGS) y sodio presentes en alfajores dietéticos de bajo valor glucídico, de la ciudad de Rosario. Materiales y Métodos: Se analizaron y categorizaron los alfajores de acuerdo al Código Alimentario Argentino (CAA) y el Sistema del Semáforo Nutricional. Resultados: Según el CAA los alfajores se clasificaron para grasas totales: 27% ?bajo contenido? y ninguno ?no contiene?; para AGS: 13%: ?bajo contenido?, 34%: ?no contiene?; y para sodio: 13%: ?bajo contenido?, 7%: ?muy bajo contenido? y ninguno ?no contiene?. Para todos los nutrientes, la mayoría de los alfajores no fue posible clasificar por exceder su contenido la clasificación del CAA. Según la metodología del Semáforo los alfajores presentaron para grasas totales: 27%: ?bajo contenido? y 73%: ?mediano contenido?; para AGS: 47%: ?bajo contenido?, 20%: ?mediano contenido? y 33%: ?alto contenido?; y para sodio: 20%: ?bajo contenido? y 80%: ?mediano contenido?. Conclusión: Ningún alfajor cumplió con los requisitos nutricionales para ser clasificado como adecuado, el 67% se clasificó como medianamente adecuado y el 33% como no adecuado. Según el CAA, la mayoría de los alfajores no se pudieron clasificar por no estar contemplado su alto contenido en los nutrientes analizados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240388,"idioma_id":4,"titulo":"Losses of nutrients and anti-nutrients in red and white sorghum cultivars after decorticating in optimised conditions","resumen":"The aims were to optimise pearling process of red and white sorghum by assessing the effects of pearling time and grain moisture on endosperm yield and flour ash content and to assess nutrient and anti-nutrient losses produced by pearling different cultivars in optimised conditions. Both variables significantly affected both responses. Losses of ashes (58%), proteins (9.5%), lipids (54.5%), Na (37%), Mg (48.5%) and phenolic compounds (43%) were similar among red and white hybrids. However, losses of P (30% vs. 51%), phytic acid (47% vs. 66%), Fe (22% vs. 55%), Zn (32% vs. 62%), Ca (60% vs. 66%), K (46% vs. 61%) and Cu (51% vs. 71%) were lower for red than white sorghum due to different degree of extraction and distribution of components in the grain. Optimised pearling conditions were extrapolated to other hybrids, indicating these criteria could be applied at industrial level to obtain refined flours with proper quality and good endosperm yields.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240389,"idioma_id":4,"titulo":"Low level of red seaweed Pyropia columbina added to extruded maize products promotes colonic and systemic antioxidant environment in growing Wistar rats","resumen":"The aim of this work was to evaluate the effect of consumption of extruded maize product added with a low level of the red seaweed Pyropia columbina on colonic and systemic oxidative status using a growing Wistar rat model. Twenty-four (n = 24) male Wistar rats were fed for 60 days with control (C), extruded maize product group (M), or extruded maize product added with red seaweed P. columbina (MP) diets. Rats fed whit MP showed higher catalase (CAT) and glutathione reductase (GR) colon expression than those fed with M or C. Beneficial effects on intestinal mucosal barrier function were observed, which was manifested in decrease of cecal pH (10%) and mucinase activity (67%) and increase of sIgA content (53%). Rats fed with MP diet showed lower cyclooxygenase-2 (COX-2; 43%), inducible nitric oxide synthase (iNOS; 49%), and NF-êâ transcription factor (27%) expression in distal colon than those fed with M or C diets. Also, MP diet exerted a significant antioxidant effect on the serum and liver, increasing hepatic redox index, CAT, and GR activity. Apparent calcium absorption, total skeleton bone mineral content, and bone mineral density of total body were the same among groups. The type of dietary fiber and phenolic compounds from P. columbina could promote antioxidant environment in growing Wistar rats.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240391,"idioma_id":4,"titulo":"Increased cropping intensity improves crop residue input to the soil and aggregate-associated soil organic carbon stock","resumen":"Many South American agroecosystems are based mainly on soybean [Glycine max (L.) Merr.] as a sole crop in the year, which has increased concerns regarding soil conservation and ecosystems sustainability. The increase in cropping intensity (CI) has been suggested as a strategy to improve crop residue inputs, which in turn, may increase soil aggregation and soil organic C (SOC) storage, while maintaining or even increasing total sequence yields. Our objective was to evaluate the relationships between CI and crop residue input with SOC storage and soil aggregation in two contrasting northeastern Argentinean Pampas soils under no-till. Two parallel experiments were established in a Mollisol and a Vertisol evaluating six cropping sequences, starting from soybean monoculture and increasing the number of crops per year and crop diversity. Crop residue inputs to the soil (aboveground biomass, belowground biomass and total biomass), grain yield, the amount of macroaggregates (MA), SOC stored inside macroagregates (SOCMA) and total SOC stocks were measured in both soils two years after the beginning of cropping sequences, at three soil depths. Soil organic C stocks, MA and SOCMA were all positively related with CI in both soils at 0?5 cm depth. All soil variables were lowest in simple rotations (soybean monoculture) and increased in more complex rotations (double cropping with cereals and legumes), although differences were significant (P < 0.05) only in the top soil (0?5 cm depth). Grain yields and crop residues followed a similar pattern being higher in rotations that included maize (with yields expressed as grain mass or as glucose equivalent mass) and lower in soybean monocultures. The highest protein yields were obtained in sequences with wheat and soybean double cropping. Increases in CI under no-till seem to be a useful strategy to improved residue inputs, soil aggregates and SOC stocks. Our results provide valuable evidence for stakeholders and policy-makers to improve SOC sequestration and soil health in agroecosystems of humid temperate croplands.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240393,"idioma_id":4,"titulo":"XRD and EBSD analysis of anisotropic microstructure development in cold rolled F138 stainless steel","resumen":"The microstructural characteristics of deformation-processed materials highly influence their mechanical properties. For a complete characterization of a microstructure both local and global information must be gathered, which requires the combination of different analysis techniques. X-ray and Electron Backscatter Diffraction were used in the present paper to characterize the deformation induced in a cold rolled F138 austenitic stainless steel sample. The results obtained using laboratory and synchrotron X-ray sources were compared and combined with EBSD quantitative results, allowing the global and local characterization and orientation dependence of the deformation microstructure. A particular behavior was observed in the XRD data corresponding to the planes with &#8741; ND, likely due to a smaller amount of defects accumulated in the crystals with that particular orientation. EBSD was used to separate the scans data into partitions and to calculate misorientation variables and parameters, showing that this behavior can be attributed to a combination of larger grain sizes, lower local boundary misorientations and dislocation densities for crystals having &#8741; ND. Several conclusions, of general validity for the evaluation of microstructure anisotropy, can be extracted from the results.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240395,"idioma_id":5,"titulo":"Articulaciones estratégicas en comunicación\/ educación para leer a las políticas públicas inclusivas en la educación de jóvenes y adultos en la Argentina (2003-2015)","resumen":"El paradigma de los DDHH en Argentina se constituyó como un eje de la articulación estratégica de las políticas públicas de inclusión educativa en el periodo 2003\/2015. La perspectiva de producción de conocimientos desde comunicación\/educación encontró en dicho paradigma y su incidencia en las políticas públicas un anclaje estratégico para su desarrollo. Una de las articulaciones o conexiones nodales de dicho paradigma son las políticas públicas de inclusión educativas de jóvenes y adultos. En este artículo se presentan algunas coordenadas teóricas respecto del campo de Comunicación\/Educación como clave de lectura del mencionado proceso. Esto se realiza en el marco de una sistematización documental de las políticas públicas que atañen a la educación de jóvenes y adultos en la Argentina y en la provincia de Buenos Aires en particular.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240397,"idioma_id":4,"titulo":"Supplementation with Docosahexaenoic Acid and Extra Virgin Olive Oil Prevents Liver Steatosis Induced by a High-Fat Diet in Mice through PPAR-&alpha; and Nrf2 Upregulation with Concomitant SREBP-1c and NF-kB Downregulation","resumen":"Scope: Non alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease, for which there is no validated drug therapy at present time. In this respect, the polyunsaturated fatty acid docosahexaenoic acid (C22:6 n-3, DHA) modulate lipid metabolism in the liver, and extra virgin olive oil (EVOO) has hepatoprotective effects.Methods and results: Effect of combined docosahexaenoic acid (DHA; C22:6 n-3) andextra virgin olive oil (EVOO) administration to mice on oxidative stress and metabolic disturbances induced by high-fat diet (HFD) was evaluated. Male C57BL\/6J mice were fed with a control diet (CD; 10% fat, 20% protein, 70% carbohydrates) or an HFD (60% fat, 20% protein, 20% carbohydrates) for 12 wk. Animals were supplemented with DHA (50 mg\/kg\/day), EVOO (50 mg\/kg\/day), or DHA+EVOO through oral route. DHA+EVOO cosupplementation resulted in greater protection (p<0.05) over that elicited by DHA or EVOO supply alone, when compared to the damage induced by HFD. DHA+EVOO significantly reduced hepatic steatosis, oxidative stress, systemic inflammation, and insulin resistance.Conclusion: Synergistic beneficial effects of DHA+EVOO supplementation were associated with the activation\/inactivation of key transcription factors involved in the above-mentioned processes. Data presented indicate that dietary supplementation with DHA+EVOO drastically reduces the development of NAFLD.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240398,"idioma_id":5,"titulo":"Practicas Performáticas Multimediales y Educación","resumen":"El presente artículo se enmarca dentro de la investigación del Proyecto de Investigación y Desarrollo titulado Prácticas Performáticas Multimediales, Redes Telemáticas y Educación, Código: B315, Facultad de Bellas Artes, Universidad Nacional de La Plata. Se trabajará la temática del cuerpo a través del vínculo con la performance y las tecnologías digitales planteando la necesidad de que conste un corpus de conocimientos que al presente están fuera del currículo académico y de enseñanza, y que podrían eventualmente ser incluidas a sus programas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240406,"idioma_id":5,"titulo":"Producción de tesinas y géneros académicos","resumen":"El texto refiere a los avances de investigación del GIC  ?Producción de géneros disciplinares y de graduación en Ciencias de la Comunicación?(2016\/2017) que continúa la línea de estudios anteriores que se iniciaron en el año 2011 hasta la fecha. Surgió motivado por la preocupación institucional acerca de las dificultades que presentan los estudiantes a la hora de producir sus tesinas de grado. Se trabajó primero con las esquematizaciones que ellos tenían sobre el objeto, los tutores y los tesistas, con el fin de intervenir favorablemente sobre ese diagnóstico. Algunas de las conclusiones remiten a los obstáculos relacionados con el proceso de escritura, sin embargo, éste no es el único problema, sino el dominio de habilidades que abarcan una alfabetización semiótica integral.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240407,"idioma_id":4,"titulo":"Resolving the circumstellar environment of the Galactic B[e] supergiant star MWC 137 from large to small scales.","resumen":"The Galactic object MWC 137 was suggested to belong to the group of B[e] supergiants. However, with its large-scale optical bipolar ring nebula and the high velocity jet and knots, it is a rather atypical representative of this class. We performed multi-wavelength observations spreading from the optical to the radio regime. Based on optical imaging and long-slit spectroscopic data we found that the northern parts of the large-scale nebula are predominantly blue-shifted, while the southern regions appear mostly red-shifted. We developed a geometrical model consisting of two double-cones. While various observational features can be approximated with such a scenario, the observed velocity pattern is more complex. Using near-infrared integral-field unit spectroscopy we studied the hot molecular gas in the close vicinity of the star. The emission from the hot CO gas arises in a small-scale disk revolving around the star on Keplerian orbits. While the disk itself cannot be spatially resolved, its emission is reflected by dust arranged in arc-like structures and clumps surrounding MWC 137 on small scales. In the radio regime we mapped the cold molecular gas in the outskirts of the optical nebula. We found that large amounts of cool molecular gas and warm dust embrace the optical nebula in the east, south and west. No cold gas or dust were detected in the north and north-western regions. Despite the new insights on the nebula kinematics gained from our studies, the real formation scenario of the large-scale nebula remains an open issue.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240411,"idioma_id":4,"titulo":"Resistant nematodes in cattle: Pharmaco-therapeutic assessment of the ivermectin- ricobendazole combination","resumen":"ver archivo adjunto","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240412,"idioma_id":4,"titulo":"Comparison of two sedation protocols for short electroretinography in cats","resumen":"AbstractObjectives The objectives were to compare two different sedative combinations, xylazine?ketamine anddexmedetomidine?ketamine, on the short electroretinography (ERG) protocol and their impact on sedative effect,reversal times and physiological variables in cats.Methods Six healthy spayed female domestic cats were sedated using one of two ketamine-containing protocols:intramuscular xylazine hydrochloride (1 mg\/kg) plus ketamine hydrochloride (3 mg\/kg) (XK), and dexmedetomidinehydrochloride (5 &#956;g\/kg) plus ketamine hydrochloride (3 mg\/kg) (DK). A short ERG protocol was recorded fromthe left eye of each cat under XK and DK sedation. Thirty minutes later, the effects were reversed with yohimbineor atipamezole for the XK and DK treatment, respectively. The cats were evaluated for time to recumbency, timeto head elevation, and time to standing position after reversal treatments. Other variables recorded were: systolicblood pressure, cardiac rhythm, heart rate, pulse oximetry and respiratory rate. Recorded ERG variables includeda- and b-wave amplitudes and implicit times under photopic, scotopic and scotopic mixed ERG conditions.Results Time to lateral recumbency with XK was shorter than for DK (P 0.05).Conclusions and relevance The present study shows that XK and DK treatments are chemical restraint alternativesfor ERG recording in cats, with only significant differences in the photopic b-wave amplitude.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240413,"idioma_id":4,"titulo":"Understanding the main route of drug entry in adult Fasciola hepatica : Further insights into closantel pharmacological activity","resumen":"Closantel (CLS) is highly effective against adult liver flukes after its oral or subcutaneous (sc) adminis- tration in ruminants. Trans-tegumental diffusion and oral ingestion are the two potential routes available for the entry of drugs into Fasciola hepatica. The work reported here contributes to improve the un- derstanding of CLS pharmacology. The main goals of were: I) to determine the pattern of in vivo CLS accumulation into adult F. hepatica and relevant tissues in CLS-treated sheep; II) to investigate the in- fluence of the physicochemical composition of the incubation medium on the CLS diffusion process into adult F. hepatica; III) to assess the ovicidal activity of CLS against F. hepatica eggs; and IV) to investigate the in vivo effect of CLS treatment on glutathione S-transferases activity in adult liver flukes exposed to CLS. Fourteen healthy sheep were each orally infected with 75 F. hepatica metacercariae. Sixteen (16) weeks after infection, animals were treated with CLS by oral (n 1&#8260;4 6, 10 mg\/kg) or sub-cutaneous (sc) (n 1&#8260;4 6, 5 mg\/kg) route. At 12, 24 and 36 h post-treatment, animals were sacrificed (n 1&#8260;4 2) and samples of blood, bile and adult F. hepatica were collected. In addition, flukes recovered from non-treated sheep (n 1&#8260;4 2) were ex vivo incubated (60 min) in the presence of CLS in either RPMI or bile as incubation medium. CLS concentration was measured by HPLC. The ovicidal activity of CLS was investigated using eggs obtained from the bile of untreated sheep. Finally, glutathione S-transferase activity in F. hepatica recovered from untreated and CLS-treated sheep was assessed. In the in vivo studies, the highest CLS concentrations were measured in plasma and adult liver flukes. A positive correlation was observed between CLS concentration in plasma and in F. hepatica. Results obtained in the current work indicatehat the in vivo accumulation of CLS into adult liver flukes occurs mainly by the oral route. After ex vivo incubation, the uptake of CLS by the parasite was markedly diminished in the presence of bile compared with that observed in the presence of RPMI as incubation medium. CLS lacks ovicidal activity at thera- peutically relevant concentrations. Lastly, CLS significantly increased glutathione S-transferase activity in flukes recovered at 12 h (oral treatment) and 24 h (sc treatment), compared to the control liver flukes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240415,"idioma_id":4,"titulo":"Serum IgE and IgG4 against muscle larva excretory-secretory products during the early and late phases of human trichinellosis","resumen":"Abstract In human trichinellosis, the relevance of the presenceand persistence of specific serum IgE and IgG4 duringthe early and late phases of infection is still controversial.The aim of this work was to determine the percentage ofhuman sera presenting IgE and IgG4 against Trichinellaspiralis muscle larvae excretory-secretory products as wellas their levels during the early and late phases of the infection.The antigen recognition pattern by serum total immunoglobulins(IgGAM), IgE, and IgG4 was assessed over time. Serumsamples during early and late phases were analyzed by ELISAand immunoelectrotransfer blot (IETB).Results showed that (a)?IgE and IgG4 are present at constantlevels in both phases; (b)?IgE recognized the glycoproteinsof ~ 45 and ~ 55 kDa and IgG4 only the ~ 45 kDa; (c)?in the late phase, the percentage of specific IgE positive serawas higher than that of specific IgG4 by IETB; while in serumsamples taken during the early phase, no differences werefound between both isotypes; (d)?both isotypes displayeddifferent glycoprotein recognition patterns: the pattern correspondingto IgE was coincident with that of IgGAM, comprisingseven glycoproteins (ranging from ~ 116 to ~ 29 kDa),whereas IgG4 revealed four glycoproteins (ranging from ~97 to ~ 45 kDa), showing a different sera recognition percentagedepending on the phase studied.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240416,"idioma_id":5,"titulo":"Una experiencia de capacitación semipresencial en el marco de la Ley de Seguridad Eléctrica de la Provincia de Córdoba","resumen":"Este artículo relata la experiencia de capacitación realizada durante el año 2016 por el Centro de Vinculación del Laboratorio de Máquinas Eléctricas y Baja Tensión de la Facultad de Ciencias Exactas, Físicas y Naturales de la Universidad Nacional de Córdoba.Durante el mencionado año, luego de la firma de un convenio con el Ente Regulador de Servicios Públicos de la Provincia de Córdoba se desarrolló un curso semipresencial que permitió capacitar y certificar a los profesionales que, posteriormente formarían a los idóneos con aspiraciones a ser Instaladores Electricistas Habilitados, cumpliendo lo dispuesto por  la reglamentación de la Ley 10.281. Este contexto se tomó como una oportunidad y un desafío para diseñar y desarrollar una propuesta de capacitación innovadora - primera y pionera en su tipo- que permitiera cubrir la formación de capacitadores a lo largo de toda la provincia de Córdoba en un corto período de tiempo. Esto trajo como consecuencia, la combinación de esfuerzos del equipo de docentes responsables del mencionado centro de vinculación como así también del Equipo de Tecnología Educativa e Innovación de la unidad académica citada. Compartimos las razones que fundamentaron dicho proyecto y algunos conceptos claves que lo sostuvieron.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240418,"idioma_id":4,"titulo":"Are the small-sized plankton communities of oligotrophic ecosystems resilient to UVR and P pulses?","resumen":"Evaluating how environmental stressor interactions influence ecosystem structure and functioning is critical to understanding the response of ecosystems to global change. We exposed a species-poor planktonic community to P pulses in the absence and presence of solar ultraviolet radiation (UVR). We used a field-mesocosm study in an oligotrophic mid-altitude lake to test the hypothesis that interaction between these factors affects the community?s diversity and composition, but not its biomass-size spectrum, making this community resilient in terms of its C-transfer function. Our findings show that P pulses and UVR affected the relative abundance of different planktonic populations. The abundance of phytoplankton was enhanced strongly by P pulses and secondarily by UVR. The UVR × P interaction affected only the smallest autotrophic species. Chlorococcal abundance increased, whereas chroococcal cyanobacteria decreased. However, UVR had a much more pronounced effect than P on the composition of microcrustaceans, and both factors interactively affected their biomass. Hence, the biomass-size spectrum was not resilient to the UVR × P pulse interaction. The steepness of the slope increased under P-pulse conditions because zooplankton were not able to grow concomitantly with phytoplankton, as confirmed by the low zooplankton to phytoplankton biomass ratio (Z&#8758;P). The observed planktonic changes under new foreseeable conditions that include an increase in UVR fluxes and P inputs might decouple the C cycle in inland oligotrophic lakes in the Mediterranean region.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240420,"idioma_id":5,"titulo":"Diseño y optimización de redes de distribución de agua utilizando algoritmos Genéticos.","resumen":" Diseño y optimización de redes de distribución de agua utilizando algoritmos Genéticos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240421,"idioma_id":4,"titulo":"&ldquo;Fibronectin from oviductal cells fluctuates during the estrous cycle and contributes to sperm-oviduct interaction in cattle&rdquo;","resumen":"During the passage of sperm through the oviduct, spermatozoa bind to the oviductal epithelium and form the oviductal reservoir. This interaction keeps the fertilizing capacity of sperm until ovulation-associated signals induce sperm release from the oviductal epithelium, allowing the transit of spermatozoa to the fertilization site. Fibronectin is a glycoprotein from the extracellular matrix that binds to &#945;5&#946;1 receptors. Fibronectin has been found to be expressed in the oviduct, whereas &#945;5&#946;1 has been found to be expressed in the sperm of different species. Fibronectin is involved through &#945;5&#946;1 in sperm functions. The aim of this work was to study the participation of oviductal fibronectin in the regulation of the sperm-oviduct interaction in cattle. We found that oviductal epithelial cells differentially expressed all mRNA splice variants of fibronectin during the estrous cycle. Fibronectin was localized in the apical region of oviductal epithelial cells and fibronectin levels in the oviductal fluid fluctuated during the estrous cycle. Also, bovine spermatozoa expressed &#945;5&#946;1. Using in vitro sperm-oviduct co-cultures, we found that spermatozoa were attached to the oviductal epithelium through &#945;5&#946;1. The incubation of co-cultures with fibronectin induced sperm release from the oviductal cells through &#945;5&#946;1. The sperm population released from oviductal cells by fibronectin was enriched in motile and capacitated spermatozoa. Based on our in vitro culture system results, we propose that fibronectin and &#945;5&#946;1 are involved in the sperm-oviduct interaction. Also, an increase in fibronectin levels in the oviductal fluid during the pre-ovulatory period may promote sperm release from the oviductal epithelium in cattle","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240423,"idioma_id":4,"titulo":"Endogenous lysophosphatidic acid participates in vascularisation and decidualisation at the maternal&ndash;fetal interface in the rat","resumen":"Lysophosphatidic acid (LPA) affects several female reproductive functions through G-protein-coupled receptors. LPA contributes to embryo implantation via the lysophospholipid LPA3 receptor. In the present study we investigated the participation of endogenous LPA signalling through the LPA3 receptor in vascularisation and decidualisation, two crucial events at the maternal-fetal interface. Pregnant rats were treated with diacylglycerol pyrophosphate (DGPP), a highly selective antagonist of LPA3 receptors, on Day 5 of gestation. Pregnant rats received intrauterine (i.u.) injections of single doses of DGPP (0.1mgkg-1) in a total volume of 2&#956;L in the left horn (treated horn) in the morning of GD5. DGPP treatment produced aberrant embryo spacing and increased embryo resorption. The LPA3 receptor antagonist decreased the cross-sectional length of the uterine and arcuate arteries and induced histological anomalies in the decidua and placentas. Marked haemorrhagic processes, infiltration of immune cells and tissue disorganisation were observed in decidual and placental tissues from sites of resorption. The mRNA expression of three vascularisation markers, namely interleukin 10 (Il10), vascular endothelial growth factor (Vegfa) and vascular endothelial growth factor receptor 1 (Vegfr1), was reduced at sites of resorption from Day 8. The results show that the disruption of endogenous LPA signalling by blocking the LPA3 receptor modified the development of uterine vessels with consequences in the formation of the decidua and placenta and in the growth of embryos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240428,"idioma_id":5,"titulo":"Morfometría geométrica en puntas de proyectil lanceoladas de las Sierras Centrales, Argentina","resumen":" Los resultados que se exponen y discuten en este trabajo constituyen un acercamiento inicial a la utilización de la morfometría geométrica como metodología aplicada al estudio de puntas de proyectil lanceoladas de las Sierras Centrales. Este tipo de instrumentos líticos pertenecientes a los sistemas de armas utilizados por los cazadores recolectores, comúnmente denominadas puntas 'ayampitín', constituyen un elemento diagnóstico de la tecnología existente en el área durante el Holoceno Medio. El análisis de variables morfométricas y su relación con la materia prima empleada permitió abordar la historia de vida de los artefactos y las variables de diseño existentes, reflejando una amplia variabilidad. El conjunto de cuarenta piezas es el primero al que se aplica esta metodología, por cuanto los resultados obtenidos son preliminares. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240438,"idioma_id":5,"titulo":"Processos de expansão e limites a privatização da atenção à saúde na América Latina: além das tipologias","resumen":"O estudo teve como objetivo fazer uma revisão bibliográfica sobre os sistemas de saúde e estudos comparados em políticas e sistemas de saúde para identificar os principais aportes dos mesmos na análise da privatização, especialmente, no papel das organizações que comercializam planos e seguros de saúde nos sistemas nacionais de saúde em países da América Latina. A revisão foi focada em analisar a adequação das perspectivas ou propostas teórico-metodológicas de seus indicadores para dimensionar a participação do sector privado da saúde, e sua interação com os sistemas nacionais de saúde. Deste modo, procuramos problematizar a adequação, os limites e as potencialidades dos mesmos, estudando os processos de privatização nos sistemas de saúde de países da América Latina. As análises comparadas de alguns elementos específicos, como as análises de custos em saúde, a capacidade instalada, a população coberta com planos e seguros de saúde, nos permitiu identificar as vinculações e contradições existentes nos sistemas, ao respeito das relações com o sistema público--privado, além de questionarmos o uso das classificações tradicionais com as quais foram definidos os diferentes sistemas de saúde em nossa região. Nosso desafio foi romper com algumas explicações lineares o carentes de contradições sobre as análises dos sistemas de saúde. Desde essa perspectiva, é necessário questionar as categorias ou tipologias que foram desenvolvidas e usadas de forma recorrente, com o fim de discuti-las e repensá-las a fim de avançar numa compreensão mais rigorosa das nossas realidades, assim como estimular novos debates e explicações sobre esta questão.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240456,"idioma_id":5,"titulo":"Eficiencia de las unidades de conservación definidas en la Reserva Natural Iberá (Argentina) en la protección de la diversidad de reptiles","resumen":"Ante la acelerada pérdida de biodiversidad causada por actividades humanas, las áreas protegidas (APs) constituyen la principal respuesta para mitigar esta crisis. La Reserva Natural Iberá (RNI) incluye 13000 km2 de territorios privados y fiscales, que contienen humedales y tierras altas con elevada biodiversidad, endemismos e importantes poblaciones de especies amenazadas. Para implementar su conservación, a finales del siglo pasado se definieron cinco Unidades de Conservación (UC) priorizadas en infraestructura y guardaparques, seleccionadas mediante criterios pobremente explicitados. En este trabajo definimos áreas prioritarias para la conservación (APC) usando los patrones de distribución de los reptiles en la RNI, para evaluar la eficiencia de las UC instauradas y detectar otras posibles áreas a ser consideradas en gestiones de conservación. La RNI se dividió en 28 celdas de 0,25° de latitud-longitud y mediante muestreos de campo y revisión de colecciones se obtuvieron 1482 registros de 71 especies de reptiles computándose su presencia\/ausencia en las celdas. Se calculó por celda riqueza específica e Índice Combinado de Biodiversidad (ICB) (que incluye rareza y grado de amenaza). Las APC fueron definidas mediante una búsqueda exacta (Complementariedad), obteniendo el mínimo conjunto de áreas que contuvieran a todas las especies y valores del ICB, lo que se denomina ?eficiencia máxima?. La superficie mínima necesaria que representa a todas las especies es de diez celdas (36%) y sólo dos incluyen UC actuales. Se necesitan adicionar ocho celdas para cubrir los vacíos de conservación de reptiles, particularmente en el norte de la RNI. Sobre 20 especies amenazadas o insuficientemente conocidas, 12 (60%) no fueron registradas en celdas con UC. Proponemos UC adicionales para efectivizar la protección de todos los reptiles e incluir especies amenazadas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240459,"idioma_id":5,"titulo":"LA CONSTRUCCIÓN COLECTIVA DEL CONOCIMIENTO Un imperativo ético frente al individualismo","resumen":"Reconociendo el carácter furibundo del surgimiento de las ciencias sociales, en este escrito nos proponemos la necesidad de problematizar la propia práctica de conocimiento y su implicancia en los diversos mecanismos de poder del que resultan-generan-reproducen. Más específicamente, realizamos un análisis, en clave de ejercicio arqueológico y genealógico, sobre nuestro trabajo colectivo y sobre nosotros\/as mismos\/as en tanto sujetos de la academia, a partir de la lectura que hemos hecho de la obra foucaultiana desde el año 2008 e ininterrumpidamente hasta la actualidad. Retomamos el modo en que nos ha interpelado, nutrido y modificado dicha lectura, así como también caracterizamos el escenario intelectual y político en el que se gesta nuestra inquietud, aquellas preocupaciones que nos han impulsado a conformarnos en colectivo político y, atento a ello, a la imperiosa necesidad de revisar el herramental que la obra foucaultiana brinda. Reconociendo que, en líneas generales, los sistemas académicos y los recorridos que se proponen para sus estudiantes, para los\/as becarios\/as de diversas instituciones y para sus trabajadores\/as son prioritariamente de carácter individual, reafirmamos la importancia de construir colectivos de trabajo al interior del ámbito académico, como un gesto de resistencia a lógicas de neoliberalización que permean el campo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240462,"idioma_id":5,"titulo":"Presupuesto Participativo en ciudades intermedias de la Provincia de Santa Fe: los casos de Santo Tomé, Firmat y San Lorenzo (2012-2016).","resumen":"En este artículo revisaremos las experiencias de Presupuesto Participativo (PP) desarrolladas en tres ciudades intermedias de la provincia de Santa Fe, una de ellas ubicada a pocos kilómetros de la ciudad capital homónima: Santo Tomé; la otra localizada al sur, a poco más de 100 km de la ciudad de Rosario y San Lorenzo, a 20 km al norte de Rosario. Por su envergadura en el contexto provincial en el que están inmersas y por la cercanía con las dos ciudades centrales por su peso económico, histórico y político como los son Rosario y Santa Fe, se trata de experiencias innovadoras en ciudades de su tamaño - municipios de segunda categoría-. Pretendemos analizar y comparar los diseños institucionales de los PP de cada localidad para comprender sus alcances y desafíos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240467,"idioma_id":5,"titulo":"Farmacología en conejos (II): aspectos sanitarios  en producción cunícula","resumen":"En la primera parte de estos artículos, se ha mencionado como influyenlas bases anatómicas y fisiológicas de esta especie animal, en la posologíade los fármacos. Se señaló que debido a la falta de informaciónde estudios con fármacos para uso en conejos, es indispensable conocertales bases, que influyen en la biodisponibilidad, en la eficacia y en la seguridadde los fármacos. Se citaron como ejemplos, los efectos adversosde los antimicrobianos, pues, como se verá en esta segunda parte, sonmuy empleados en cunicultura. En este segundo artículo, se consideraránlos problemas de salud que se observan en esta especie, que puedeser utilizada para diversos fines y ello ha definido cinco categorías deexplotación: obtención de carne para consumo humano, obtención depieles y\/o de pelos, como animales de compañía, animales de suelta orepoblación y finalmente como individuos de experimentación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240476,"idioma_id":5,"titulo":"Reseña. Entre el humo y la niebla. Guerra y cultura en América Latina","resumen":"Reseña de Entre el humo y la niebla. Guerra y cultura en América Latina, de Felipe Martínez-Pinzón y Javier Uriarte (Eds.). El libro recopila catorce artículos que abordan la cuestión de la guerra y su representación en América Latina, a partir de la hipótesis común de que lo bélico constituye un fenómeno a la vez opaco y ubicuo y que por eso mismo supone enormes potencialidades narrativas. Los conflictos analizados van desde el período post independentista -por ejemplo, la llamada Guerra de Castas, que tuvo lugar en México en 1847- hasta las 'guerras narco' de Colombia y Brasil a fines del siglo XX.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240478,"idioma_id":5,"titulo":"El giro documental en algunas producciones literarias y cinematográficas de hijos de desaparecidos","resumen":"Nota: El presente trabajo forma parte del dossier 'Lazos inestables. Cine y literatura en la contemporaneidad latinoamericana' que coordiné junto con el Dr. Marcos Zangrandi y que será publicado en Cuadernos de Literatura durante 2017. Resumen: En los últimos años, es posible detectar que en parte de la literatura argentina un giro documental ha venido a completar, ya que no ha sustituir, el giro subjetivo al que una década atrás se refirió, entre otros, Beatriz Sarlo. El registro etnográfico de los lenguajes, la revalorización de la figura de autor, las ?incrustaciones? en el texto, casi sin mediación, de elementos de lo real o materiales textuales ?cortados y pegados? (fragmentos de mails, de diarios), la preeminencia de un vínculo de tipo indicial o metonímico con lo real por sobre lo metafórico o alegórico son algunos de los rasgos de este doble giro. En el cine argentino, entretanto, algunos de estos rasgos aparecen antes, ya durante la década del noventa, y son parte de lo que, siguiendo a Hal Foster, parte de la crítica especializada llamó ?retorno de lo real?. Este trabajo busca reflexionar en torno a las transformaciones que, en este sentido, tienen lugar tanto en la literatura como en el cine contemporáneos, así como indagar en las posibles relaciones entre ellos. Para ello, se abordará una serie de libros y películas ligados a la última dictadura militar, en los que el giro documental y subjetivo toma su forma particular de la aparición de la voz de los hijos de desaparecidos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240485,"idioma_id":4,"titulo":"Study of dielectric strength in EPDM by nondestructive dynamic mechanical analysis in high electrical field","resumen":"In the present work the value of the degree of the area swept by the polymer chain due to an electrical force for a given mesostructure was related to the corresponding value of the dielectric strength. This value was deduced from the electric inclusion formalism applied to dynamic mechanical analysis (DMA) studies conducted under high electric field, which were performed in commercial ethylene-propylene-diene M-class rubber (EPDM); used for the housing of polymeric electrical insulators. EPDM samples with different arrangements of the polymer chains and crystalline degree, promoted by controlled neutron irradiation were studied. Several characterization techniques, as infrared absorption spectroscopy (IR), differential scanning calorimetry (DSC), positron annihilation lifetime spectroscopy (PALS) and dielectric strength (DS) were also used. The relationship between the DS and the degree of movement of polymer chains promoted by electrical forces coming from the electric field applied in a non destructive test as the DMA was successfully established. In fact, a larger empty space in the sample leads to larger areas swept by the polymer chains during bending under the application of the field strength in the dynamic mechanical analysis tests. Therefore, an increase in the capability of movement of charges occurs, corresponding to smaller dielectric strength values. Crystallinity improves the dielectric strength due to the increase in the internal stresses which decreases the capability of movement of the polymer chains and electric carriers by electric forces.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240486,"idioma_id":4,"titulo":"Study of the martensitic transition in Ni-Mn-Sn-Ti ferromagnetic shape memory alloys","resumen":"In the present work, mechanical spectroscopy measurements as a function of temperature and strain have been performed in (at.%) Ni50Mn37Sn13-xTix (x=0, 0.5 and 2) ferromagnetic shape memory alloys in order both to study martensitic transition phenomenon and also to determine its temperature of appearance. For mechanical spectroscopy measurements, a five elements piezoelectric device recently developed has been used. In addition, other characterization techniques as, differential thermal analysis and superconducting quantum interference magnetic spectroscopy, were also used. Besides, relaxation processes near the martensitic transition temperature have been also observed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240487,"idioma_id":4,"titulo":"Influence of thermal treatments on the mechanical properties and the martensitic transformation in Fe-Pd-Mn ferromagnetic shape memory alloy","resumen":"The effects of high temperature thermal treatments on the hardening behaviour, the damping capacity and the martensitic transformation in Fe66.8Pd30.7Mn2.5 Ferromagnetic Shape Memory Alloy have been determined by mechanical spectroscopy. Annealing below 753 K, lead to a hardening of the alloy without a marked decrease in the damping capacity. In addition, they increase both the austenite finish transformation temperature and the intensity of the damping peak related to the martensitic transformation. This variation can be controlled by the small volume fraction precipitation of small &#945; phase particles. In contrast, thermal treatments performed above 753 K lead to a further hardening of the alloy, but they decrease the austenitic finish transformation temperature and the intensity of the damping peak related to the martensitic transformation; as a consequence of the decomposition of the metastable &#947; phase into the &#945;+&#947;1 stable phases. In addition, two new damping peaks related to the mobility of dislocations and grain boundaries have been discovered at around 700 K and 900 K, respectively","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240490,"idioma_id":5,"titulo":"Secundaria y formación de directivos. Lo realizado y lo por venir. Del liderazgo mercantilizado a la conducción crítica y desde el Estado","resumen":"La conducción de las escuelas secundarias es clave para generar entornos cotidianos de aprendizaje e inclusión. Así y todo, pocos docentes reciben capacitación sobre la dirección de estas instituciones. El artículo aborda los múltiples sentidos que, desde distintas concepciones de política educativa, se otorga a la gestión directiva de las instituciones escolares.Esta producción se propone resignificar la función directiva  en términos de gobernar las instituciones y conducir y formar a sus equipos docentes.Se contraponen diversos paradigmas en trono al tema y se analiza como caso la política del Programa Nacional de Formación permanente llevada a cabo entre 2013 y 2015 por el Ministerio de Educación de la Nación, junto con los Ministerios de educación de las jurisdicciones y de los sindicatos docentes con representación nacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240492,"idioma_id":5,"titulo":"Reflexiones metodológicas inconclusas: el trabajo de campo en el ámbito de la justicia penal juvenil","resumen":"En el presente trabajo pretendemos articular algunos de los contenidos, interrogantes, lecturas y aportes del proceso deconstrucción de una tesis doctoral en el ámbito de las Ciencias Sociales. En la misma, abordamos las transformacionesacaecidas en los procesos de trabajo sobre los otros (Dubet, 2013) durante los últimos doce años, en el marco deinstituciones de régimen cerrado pertenecientes al ámbito de la justicia penal juvenil en Argentina. En este sentido, nospropondremos reflexionar en torno a las características del enfoque socioantropológico desde el cual llevamos a cabonuestra investigación, identificando tanto sus rasgos específicos así como las tensiones emergentes a partir de supuesta en juego en nuestro trabajo de campo","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240493,"idioma_id":4,"titulo":"Effect of Rh Addition to Ni\/MgO-Al2O3 Catalysts for Dry Reforming of Methane","resumen":"Objective: This study has analyzed the performance of Ni and Ni-Rh catalysts based on MgO\/g-Al2O3 in the process of dryreforming of methane (DRM). Methods\/Statistical Analysis: The samples were prepared using the incipient wetnessimpregnation method and were characterized by N2 adsorption, X-ray diffraction (XRD), temperature-programmedreduction (TPR), diffuse reflectance spectroscopy (DRS), surface acidity, X-ray photoelectron spectroscopy (XPS), thermalgravimetric analysis (TGA), and Raman spectroscopy. The catalysts were reduced with hydrogen and measured in thereaction of CH4 with CO2 at two CH4\/CO2 ratios. Findings: The 0.5% Rh addition to Ni\/MgO-g-Al2O3 improves the activityand the stability for this process. In the bimetallic catalysts, the reduction temperature of the active phase decreases dueto the hydrogen spillover mechanism from the noble metal to the catalyst surface, which favors their catalytic activity. Onthe other hand, the interaction between Rh and the support would be the cause for the better performance of bimetalliccatalysts. The Rh-Ni\/MgO-g-Al2O3 catalyst is the most active, indicating that the impregnation order affects the catalyticbehavior. Improvements\/Applications: This study gives promising results for this type of catalyst, also showing the effectof the catalyst preparation on the activity and its relationship with deactivation by coke.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240494,"idioma_id":4,"titulo":"Predicting the Bioconcentration Factor Through a Conformation- Independent QSPR Study","resumen":"The ANTARES dataset is a large collection of known and verified experimental bioconcentration factor data, involving 851 highly heterogeneous compounds from which 159 of them are pesticides. In this Special Issue devoted to 'Computational Toxicology and Fate of Pesticides?, we predict the Bioconcentration Factor of the ANTARES dataset by means of a conformation independent QSPR approach. A large number of 27,017 molecular descriptors are explored, with the main intention of capturing the most relevant structural characteristics affecting the studied property. The structural descriptors are derived with different freewares, such as PaDEL, Epi Suite, CORAL, Mold2, RECON and QuBiLs-MAS, and so it is interesting to find out the way that the different descriptor softwares complement each other in order to improve the statistical quality of the established QSPR. The best multivariable linear regression models are found with the Replacement Method variable subset selection technique. The proposed QSPR model improves previous reported models of the bioconcentration factor in the present dataset.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240495,"idioma_id":4,"titulo":"Total Oxidation of Naphthalene with Zirconia- Supported Cobalt, Copper and Nickel Catalysts","resumen":"Abstract: ZrO2 nH2O (hydrogel) impregnated with transition metals (Cu, Co, and Ni) was studied in this work as a precursor for the synthesis of CuO\/ZrO2 (CuZ), CoOx\/ZrO2 (CoZ), and NiO\/ZrO2 (NiZ) catalysts, employed in the naphthalene oxidation reaction. Fresh and catalytically used materials were characterized by different physicochemical techniques, to compare the bulk and surface behavior, with particular attention to the effect of the supported metal species? properties on the catalytic activity. Techniques such as X-ray diffraction (XRD), temperature programmed reduction (TPR), differential scanning calorimetry (DSC), Brunauer?Emmett?Teller (BET) surface area analyzer, diffuse reflectance spectroscopy (DRS UV?vis), and Raman spectroscopy, allow for establishing structural and textural aspects of the support, as well as the surface coordination and the accessibility of supported species. Results were in agreement with the CuZ > CoZ > NiZ sequence for the activity in naphthalene oxidation reaction. Electronic properties, ionic sizes, oxide phase deposition on the support surface, reducibility, metal?support interaction, and local site symmetry of metals seem to be decisive factors for the catalytic interaction with the gaseous phase.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240496,"idioma_id":5,"titulo":"PRODUCTIVIDAD DE OPERACIONES DE RALEO CON HARVESTER EN PLANTACIONES DE PINOS DEL NORESTE ARGENTINO","resumen":"Se analizó la productividad de segundos y terceros raleos en plantaciones de Pinus taeda y Pinus elliottii var. elliottii x Pinus caribaea var. hondurensis realizados con harvesters de ruedas en el Noreste Argentino. Los árboles cosechados en los segundos raleos presentaron un volumen medio de 0,43 m³ para Pinus taeda de 12 años y 0,36 m³ para Pino hibrido de 10 años, mientras que en los terceros raleos este fue de 0,71 m³ para Pinus taeda de 13 años y 0,75 m³ para Pino hibrido de 15 años respectivamente. Se desarrollaron modelos de tiempos parciales para cada una de las actividades que componen el ciclo operacional y se determinó la influencia del tipo de raleo, especie cosechada, número de productos elaborados, volumen de los árboles y forma de volteo, sobre el tiempo insumido por cada actividad. Los modelos ajustados fueron integrados en un modelo de productividad efectiva consiguiéndose un coeficiente R2 de 0,61. El volumen de los árboles resultó significativo para explicar la duración de todas las actividades evaluadas, siendo especialmente determinante en el volteo de los árboles, su desrame y trozado. El tipo de raleo afectó al tiempo de ubicación, mientras que la especie afectó al tiempo de desrame y trozado. La elaboración de hasta tres productos diferentes requirió un mayor tiempo destinado al desrame y trozado. Hubo un aumento de la cantidad de productos cuando se realizaron terceros raleos sobre Pino hibrido, respecto Pinus taeda.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240497,"idioma_id":4,"titulo":"Harvesting contractor production and costs in forest plantations of Argentina, Brazil, and Uruguay","resumen":"Timber production from forest plantations has increased substantially in South America in the last few decades. The timber harvesting process is carried out mainly through logging contractors. This research developed production and cost ´functions for logging contractors working in Misiones and Corrientes (Argentina), Paraná, Santa Catarina and Rio Grande do Sul (Brazil) and Uruguay. Data were obtained from surveys: 22 in Argentina, 35 in Brazil and 10 in Uruguay between 2008 and 2012. When considered as a share of the total production region, we sampled a weighted average of 21% of the firms, which means an annual production of 17.7 million cubic meters. Regressions of the variables species, operations, contractors and mechanization indicated that the logging costsper ton were higher in Uruguay, as were logging contract prices. The contract prices paid for thinning were significantly higher than those of clearcutting, but average logging costs did not differ significantly. A large amount of capital was needed to begin operations, but there was an inflection in the average cost curves at 50,000 tons\/month, and average costs were asymptotic at100,000 tons\/month. Logging contractors working for pulp companies have significantly higher capital value and the largest payroll. The fully mechanized logging firms had the highest capital costs. The Cobb-Douglas function was best to estimate production and cost models. Last, the size of the logging firms in these three countries was larger than those reported for southeastern USA andfor Scandinavia. However, average costs were not as low as reported in those countries.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240498,"idioma_id":5,"titulo":"Historias cotidianas y Los rubios: dos formas de narrar el pasado","resumen":"Según Gustavo Aprea (2015) hay tres modalidades de abordajeque plantean los documentales sobre la militancia que participóde los hechos ocurridos durante la Dictadura Militar Argentina(1976&#8208;1983): la primera; desde la vivencia y lo testimonial, lasegunda desde la memoria y el no&#8208;olvido, y la tercera desde laposibilidad de transmisión de la experiencia de la militanciarevolucionaria que construye modelos para las nuevasgeneraciones. Los primeros relatan la historia desde la derrota ycon una lectura política, los segundos desde el trauma y conuna lectura personal, y los terceros desde el reconocimiento ycon una lectura profesional de los hechos. En este artículo sedesarrollará el segundo grupo desde el análisis de las películasHistorias cotidianas (2001) de Andrés Habegger y Los rubios(2003) de Albertina Carri, quienes reconstruyen la militanciadesde lo afectivo, buscando un cierre a una etapa de sus vidaspor medio de una memoria fragmentada. Si bien ambosdocumentales son guionizados y dirigidos por hijos dedesaparecidos en la época de Terrorismo de Estado, ya desde eltítulo se encuentra una diferencia marcada en su abordajetemático, que se visualiza también en el tratamiento estéticonarrativo.Por ende, el presente artículo tiene como objetivollevar adelante un análisis narrativo (contemplando estructura yrecursos) de ambas obras y, a su vez, tratar de comprender susmensajes, sus significados, a la luz de la teoría expuesta pormúltiples estudiosos del cine documental político, con el finúltimo de poder establecer un punto de encuentro.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240501,"idioma_id":4,"titulo":"The riddle of mitochondrial alkaline\/neutral invertases: A novel Arabidopsis isoform mainly present in reproductive tissues and involved in root ROS production","resumen":"Alkaline\/neutral invertases (A\/N-Inv), glucosidases that irreversibly hydrolyze sucrose into glucose and fructose, play significant roles in plant growth, development, and stress adaptation. They occur as multiple isoforms located in the cytosol or organelles. In Arabidopsis thaliana, two mitochondrial A\/N-Inv genes (A\/N-InvA and A\/N-InvC) have already been investigated. In this study, we functionally characterized A\/N-InvH, a third Arabidopsis gene coding for a mitochondrial-targeted protein. The phenotypic analysis of knockout mutantplants (invh) showed a severely reduced shoot growth, while root development was not affected. The emergence of the first floral bud and the opening of the first flower were the most affected stages, presenting a significant delay. A\/N-InvH transcription is markedly active in reproductive tissues. It is also expressed in the elongation and apical meristem root zones. Our results show that A\/N-InvH expression is not evident in photosynthetic tissues, despite being of relevance in developmental processes and mitochondrial functional status. NaCl and mannitol treatments increased A\/N-InvH expression twofold in the columella rootcap. Moreover, the absence of A\/N-InvH prevented ROS formation, not only in invh roots of salt- and ABA-treated seedlings but also in invh control roots. We hypothesize that this isoform may take part in the ROS\/sugar (sucrose or its hydrolysis products) signaling pathway network, involved in reproductive tissue development, cell elongation, and abiotic stress responses.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240504,"idioma_id":4,"titulo":"Intense natural selection preceded the invasion of new adaptive zones during the radiation of New World leaf-nosed bats","resumen":"The family Phyllostomidae, which evolved in the New World during the last 30 million years, represents one of the largest and most morphologically diverse mammal families. Due to its uniquely diverse functional morphology, the phyllostomid skull is presumed to have evolved under strong directional selection; however, quantitative estimation of the strength of selection in this extraordinary lineage has not been reported. Here, we used comparative quantitative genetics approaches to elucidate the processes that drove cranial evolution in phyllostomids. We also quantified the strength of selection and explored its association with dietary transitions and specialization along the phyllostomid phylogeny. Our results suggest that natural selection was the evolutionary process responsible for cranial diversification in phyllostomid bats. Remarkably, the strongest selection in the phyllostomid phylogeny was associated with dietary specialization and the origination of novel feeding habits, suggesting that the adaptive diversification of phyllostomid bats was triggered by ecological opportunities. These findings are consistent with Simpson?s quantum evolutionary model of transitions between adaptive zones. The multivariate analyses used in this study provides a powerful tool for understanding the role of evolutionary processes in shaping phenotypic diversity in any group on both micro- and macroevolutionary scales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240505,"idioma_id":4,"titulo":"Comparative cranial ontogeny of Tapirus (Mammalia: Perissodactyla: Tapiridae)","resumen":"Skull morphology in tapirs is particularly interesting due to the presence of a proboscis with important trophic, sensory and behavioral functions. Several studies have dealt with tapir skull osteology but chiefly in a comparativeframework between fossil and recent species of tapirs. Only one study examined an aspect of cranial ontogeny, development of the sagittal crest (Holbrook. J Zool Soc Lond 2002; 256; 215). Our goal is to describe in detail the morphological changes that occur during the postnatal ontogeny of the skull in two representative tapir species, Tapirus terrestris and Tapirus indicus, and to explore possible functional consequences of their developmental trajectories. We compared qualitative features of the skull on a growth series of 46 specimens of T. terrestris ordered on the basis of the sequence of eruption and tooth wear, dividing the sample into three age classes: class Y (very young juvenile), class J (from young juvenile to young adult) and class A (full and old adult). The qualitative morphological analysis consisted of describing changes in the series in each skull bone and major skull structure, including the type and degree of transformation (e.g. appearance, fusion) of cranial features (e.g. processes, foramina) and articulations (sutures, synchondroses, and synovial joints). We then measured 23 cranial variables in 46 specimens of T. terrestris that included the entire ontogenetic series from newborn to old adults. We applied statistical multivariate techniques to describe allometric growth, and compared the results with the allometric trends calculated for a sample of 25 specimens of T. indicus. Results show that the skull structure was largely conserved throughout the postnatal ontogeny in T. terrestris, so class Y was remarkably similar to class A in overall shape, with the most significant changes localized in the masticatory apparatus, specifically the maxillary tuber as a support of the large-sized permanent postcanine dentition, and correlated changes in diastemata, mandibular body, and sagittal and nuchal crests. In the nasal region, ontogenetic remodeling affected the space for the meatal diverticulum and the surfaces for the origin of the proboscis musculature. Overall, ontogenetic trajectories exhibited more negative allometric components in T. indicus than in T. terrestris, and they shared 47.83% of allometric trends. Tapirus indicus differed most significantly from T. terrestris in the allometry of postcanine toothrows, diastemata and mandibular body. Thus, some allometric trends seem to be highly conserved among the species studied, and the changes observed showed a strong functional and likely adaptive basis in this lineage of ungulates.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240506,"idioma_id":5,"titulo":"Evaluación de la aplicación de cánula nasal de alto flujo (HFNC) con tomografía de impedancia eléctrica: a propósito de un caso","resumen":"Objetivo: Reportar un caso donde se aplicó Cánula Nasal de Alto Flujo (HFNC) con monitoreo a través de Tomografía de Impedancia Eléctrica (TIE).Método: Masculino de 81 años de edad con antecedentes de cáncer de próstata, prótesis de rodilla bilateral y osteomielitis; ingresada en la Unidad de Cuidados Intensivos por neumonía grave de la comunidad. Durante su internación se aplicó cánula nasal de alto flujo con monitoreo respiratorio avanzado.Resultados: Evolucionó satisfactoriamente y se le dio de alta con buen estado general y sin secuelas respiratorias.Conclusión: El HFNC es una intervención que está tomando un protagonismo relevante en el tratamiento  en la falla respiratoria hipoxémica. El monitoreo no invasivo como es la TIE nos proporciona una herramientas eficaz para una correcta selección y dosificación en la  forma de aplicación de este novedoso instrumento de administración de oxígeno.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240518,"idioma_id":5,"titulo":"Breve estado de la cuestión animal","resumen":"Este trabajo tiene como objetivo examinar algunas de las transformaciones que el desarrollo y la expansión de los llamados 'estudios animales' generan en el ámbito de las humanidades; más específicamente: en la creación de nuevas herramientas críticas para abordar experiencias artísticas. A partir de la lectura de dos ensayos recientes dedicados a la siempre perturbadora presencia del imaginario animal en las artes visuales, procuramos analizar algunas nociones que podrían enriquecer el campo de estudio más allá de sus límites disciplinares, proyectándose por ejemplo al terreno de la crítica literaria. Estas nociones son, entre otras, las de 'superficie', 'fenomenología animal' y 'epistemología antirrepresentacional'.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240520,"idioma_id":5,"titulo":"Una vida nueva. Imágenes y pensamiento de la animalidad en Opendoor y Paraísos de Iosi Havilio","resumen":"El trabajo se enmarca en un proyecto más amplio dedicado a estudiar los diálogos en torno del devenir de la relación humano-animal en la literatura latinoamericana de las últimas décadas, abiertos a una revisión de la -en palabras de Jacques Derrida- inmensa denegación que, durante siglos, obturó el pensamiento -teórico, científico, estético- del animal y la animalidad. Nos interesa aquí comenzar a rastrear y analizar algunos de los  procedimientos con los que dos novelas del escritor argentino Iosi Havilio participan de ese horizonte discursivo, produciendo algunos deslizamientos conceptuales que para el discurso filosófico, usualmente reglado por convenciones retóricas más rígidas, suelen estar vedados; es decir, aportándole la complejidad e intensidad propias del pensamiento literario.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240523,"idioma_id":5,"titulo":"Una promesa de felicidad. Desvíos teóricos de la crítica argentina reciente","resumen":"El artículo se propone abordar algunas aristas del diálogo que una vertiente de la crítica literaria argentina reciente, dedicada a estudiar el anudamiento literatura-vida, ha establecido con el horizonte de pensamiento poshumanista. Nuestra hipótesis de trabajo es que en ese intercambio interdisciplinar y en el esfuerzo simultáneo -y paradójico- por constituir una perspectiva teórica para abordar objetos literarios se produciría la emergencia de resistencias que, al tiempo que obturan el camino, producen desvíos sumamente productivos. Es el caso de la noción misma de literatura, cuya conceptualización contradice abiertamente la instauración de una perspectiva epistemológica biopolítica sobre el funcionamiento las prácticas artísticas -que negaría la especificidad literaria-, al tiempo que habilita una reflexión sobre los procedimientos propios de las ficciones animales, animalizadas o animalizantes en la elaboración de lo que Susan McHugh caracteriza como una 'etología narrativa'.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240524,"idioma_id":5,"titulo":"El animal biográfico","resumen":"El presente artículo parte de una pregunta aparentemente impertinente: ¿por qué los animales no tienen biografía? La respuesta parece evidente: no participando del bíos, difícilmente podrían convocar la grafía; una vida sin palabras -sin historia, sin muerte, sin política- no solicitaría -ni ameritaría- un relato. ¿A quién podría interesarle la vida de un pollo industrial, criado bajo lámparas, hacinado, alimentado incesantemente, privado del sueño hasta el momento de ser desangrado por una máquina? ¿Es eso acaso una vida? ¿Y quién podría escribirla? Con todo, el interrogante suscita algunas reflexiones e ilumina aspectos de la narración biográfica que, analizados desde una perspectiva antropocéntrica, permanecen en la sombra; en primer lugar, el prejuicio de que bíos y zoé son zonas discernibles en el ser humano y, por tanto, en su relato biográfico. El trabajo apunta, así, a examinar la imposibilidad de la biografía animal con la intuición de que en ella se exhibe la callada insistencia de la zoografía humana.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240525,"idioma_id":5,"titulo":"Editorial Monográfico 'Literatura, imágenes y políticas de la vida'","resumen":"En los últimos tiempos, los encuentros e intercambios entre las investigaciones de cuño científico enmarcadas en el campo de la llamada «cuestión animal» y el pensamiento artístico -en su faceta creadora y en su faceta crítica- se han enriquecido y extendido hasta el punto de comenzar a delinear los contornos de una nueva perspectiva de estudio: la de la biopoética. Un enfoque de la literatura y de las artes plásticas que, a través de un recentramiento de la noción de vida, propone abordajes transdisciplinares sin perder de vista la especificidad de cada lenguaje y de los procedimientos que les permiten producir formas singulares de pensamiento -pensamiento del animal y del  animal humano-. Esta perspectiva expone, asimismo, la necesidad de crear un nuevo diccionario crítico que revise las definiciones atribuidas a categorías tan fundamentales para las disciplinas humanísticas como las de sujeto, subjetividad, vida, viviente, animalidad, conocimiento, creación. Esta transformación del campo de preocupaciones y de las herramientas críticas con las que éste puede ser abordado implica también, por supuesto, un reconsideración del anudamiento arte-vida. Si la epistemología antropocéntrica entiende a la cultura como una realidad desligada de la vida animal ?es decir, como un proyecto de autocreación y autointerpretación humana-, el punto de vista biocéntrico, fuertemente arraigado en la tradición de pensamiento nietzscheana, la concibe como un fenómeno propio de la vida. El arte no será, así, considerado como una zona autónoma que actúa sobre o se deja inseminar por la vida, sino su modo propio de existencia. Es, en efecto, la relación entre vida y creación -así como lo es la de vida y poder para la biopolítica- la que alimenta y dirige el cauce del pensamiento biopoético. El presente monográfico intenta aproximarse a este nuevo campo de problemas; para ello, recoge una serie de intervenciones críticas que reflexionan sobre los desplazamientos filosóficos, políticos e imaginarios que la emergencia de un punto de vista biocéntrico produce en el ámbito investigativo de las llamadas 'poshumanidades'.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240526,"idioma_id":5,"titulo":"LAS BRECHAS ENTRE EL DISCURSO Y LA PRÁCTICA DE LA PARTICIPACIÓN: CINCO APORTES PARA LA REFLEXIÓN","resumen":"El presente trabajo aborda, desde el enfoque de las representaciones sociales, la participación como objeto de estudio a partir del análisis de las prácticas de los actores sociales. En las últimas décadas, en la Argentina se ha instaurado la participación como estrategia maestra para la implementación de políticas públicas. Existe un consenso en el discurso social y de los responsables del diseño de las políticas de la importancia de la participación. Sin embargo, en los hechos, los avances en la participación social muestran una gran brecha entre el discurso participacionista y las prácticas sociales. El artículo desarrolla un conjunto de reflexiones que se derivan de un estudio previo que toma la participación como objeto de análisis desde las perspectivas de los actores sociales. En función de esta perspectiva, se plantean cinco problemáticas en torno a las prácticas de la participación en políticas públicas: el vaciamiento del significado de la participación; las contradicciones en la propia identidad de las organizaciones y de la comunidad; el activismo político y el voluntarismo; el ejercicio intelectual de los expertos y técnicos de la participación, y el problema de la representación en las organizaciones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240528,"idioma_id":5,"titulo":"Monitoreo de condiciones de Higiene y Seguridad del ambiente en entornos industriales: Recolección y análisis de datos obtenidos de una red de sensores","resumen":"Se propone utilizar una red de sensores para el monitoreo de condiciones ambientales de Higiene y Seguridad en entornos industriales. El propósito de esta recolección de datos es dar soporte a inspecciones anuales de un auditor externo, por lo que la recolección no es crítica dado que no controlan ningún dispositivo. Las condiciones ambientales observadas son Temperatura, Humedad, Ruido y Luminosidad. La medición de parámetros físicos hace que los sensores sean la tecnología más adecuada para el monitoreo y reporte de mediciones cuantificables. Por esto se plantea el uso de redes de sensores inalámbricos debido a la integración actual de tecnología inalámbrica, computación y tecnología de sensores. Para esta recolección se utilizan dispositivos Wido y NodeMCU que permiten la comunicación de datos directamente al servidor de almacenaje; y se utiliza el protocolo MQTT para enviar los datos desde los dispositivos de sensado a un servidor.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240529,"idioma_id":5,"titulo":"Propuesta de un Observatorio de Productividad Regional","resumen":"Actualmente, el contexto de nuestra región en particular, y del país en general, requiere contar con herramientas que permitan una lectura de la situación actual del negocio y la previsión de desarrollos a corto plazo, las condiciones económicas y principalmente la productividad. Los indicadores de gestión son utilizados para la implementación de procesos productivos, dado que permiten la ejecución de ciclos de mejora continua, además de funcionar como parámetros de viabilidad de procesos y gestión. En nuestro caso nos interesan indicadores de productividad, junto con indicadores de coyuntura industrial, para así obtener una base para un análisis más profundo sobre el sector y el estado actual. Los indicadores de productividad, en términos generales, relacionan la producción de una determinada actividad con el consumo de dicha actividad, y permiten comparar la productividad de un sector frente a otro. Además, el uso de variables de contexto macroeconómicas también brinda información sobre la productividad en cuanto a la mejora de los procesos o uso de los factores productivos. En este artículo se propone la realización de encuestas cualitativas y cuantitativas que permitan el monitoreo de las principales variables de coyuntura y productividad. Además se propone tener en cuenta variables macroeconómicas del país y la región a fin de poder hacer una proyección a futuro. Esta información permitirá a quienes tienen la posibilidad de tomar decisiones en los diferentes ámbitos, conocer la realidad del sector y la proyección económica del mismo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240532,"idioma_id":4,"titulo":"Multi-Wavelength UV-Detection in Capillary Hydrodynamic Fractionation. Data Treatment for an Absolute Estimate of the Particle Size Distribution","resumen":"A new approach is proposed for estimating the particle size distribution (PSD) of hydrophobic colloids by capillary hydrodynamic fractionation (CHDF) based on UV-detection at several wavelengths. At each elution time, the multi-wavelength UV signal is used to estimate the instantaneous PSD at the detector cell by solving the involved inverse problem through an artificial neural network. Then, the global PSD is obtained as a weighted sum of the estimated instantaneous PSDs along the entire elution time interval. With the current approach, the estimation procedure is absolute in the sense that no calibration of diameters is required and the instrumental broadening introduced by the fractionation capillary is automatically compensated for. The proposed method was evaluated on the basis of narrow polystyrene standards, as follows: i) a single standard, to emulate a narrow unimodal PSD; ii) a mixture of three standards of relatively close average diameters, to emulate a broad unimodal PSD; and iii) a mixture of two standards of quite different average diameters, to emulate a bimodal PSD. Experimental results indicate that the new approach is able to produce adequate PSD estimates provided that the particle refractive index is known with a relatively high accuracy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240533,"idioma_id":4,"titulo":"Diagnosis of toxoplasmosis in pregnancy. Evaluation of latex&ndash;protein complexes by immnunoagglutination","resumen":"The aim of this work was to obtain a reagent based on latex particles for ruling out acute toxoplasmosis in pregnant women by immunoagglutination (IA). Latex-protein complexes (LPC) were previously synthesized coupling the recombinant protein of Toxoplasma gondii P22Ag and the homogenate of the parasite to latex particles with different size, chemical functionality, and charge density. LPC were tested in IA assays against a panel of 72 pregnant women serum samples. Results were analyzed through receiver operating characteristic curves, determining area under the curve (AUC), sensitivity, specificity positive and negative predictive values (PPV and NPV, respectively). It was observed that the antigenicity of proteins was not affected during sensitization by either physical adsorption or covalent coupling. The best results in the sense of maximizing discrimination of low avidity sera from chronic ones were observed for the IA test based on latex particles with carboxyl functionality and the recombinant P22Ag, obtaining an AUC of 0.94, a sensitivity of 100% and a NPV of 100%. In this way, the proposed test could be useful for the toxoplasmosis diagnosis in pregnant women, with the advantages of being cheap, rapid, and easy to be implemented.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240534,"idioma_id":4,"titulo":"Enhancing the coating properties of acrylic\/casein latexes with high protein content","resumen":"Casein-derived materials are highly attractive as a consequence of their environmental friendliness and excellent film-forming properties. Due to the casein hydrophilicity, films containing a large protein content are highly susceptible to water, thus limiting their use in coating applications. A novel approach for synthesizing waterborne acrylic?casein latexes with large content of protein and high degree of compatibilization between both components is presented. The employed synthesis strategy involves the use of a highly methacrylated casein in an emulsifier-free emulsion polymerization of acrylic monomers with the aim of controlling both the fraction of grafted biomaterial and the amount of acrylic chains linked onto the protein backbone. The performance of the resulting materials was evaluated in a water-based coating application. The used methacrylation approach allowed the maximum compatibilization of 33% of casein in the hybrid polymer. The as-obtained casein-derived films were proven to exhibit superior water resistance, which would open a new possibility for designing biobased coatings in several fields.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240535,"idioma_id":4,"titulo":"A Safety Strategy for Producing Poly(acrylic acid) of Low Molar Mass","resumen":"The synthesis of poly(acrylic acid) (PAA) of low molar mass under safe conditions is difficult due to the high polymerization rate of acrylic acid (AA) and the fast heat generation. The aqueoussolution ?semibatch? polymerization of non-ionized AA in almost starved conditions involves high initiator loads when low molar masses are required. This article proposes the simultaneous feeding of AA and nonconventional chain transfer agents (CTA) as a strategy aimed at controlling both the molar masses and the generated heat rate. Three CTAs are investigated: 2-mercaptoethanol, thioglycolic acid, and isopropyl alcohol. Even when PAA of relatively low molar mass can be produced by adequately selecting the flow rates and concentrations of both AA and CTA, it is found that the nature of CTA can have a significant effect on the polymerizations kinetics. The mechanisms responsible for these effects are discussed with the help of a representative mathematical model.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240536,"idioma_id":4,"titulo":"Latex Particles Sensitized with Proteins of Leptospira interrogans for Application in Immunoagglutination Assays","resumen":"Physical adsorption and chemical coupling of recombinant proteins of Leptospira interrogans onto polystyrene and core-shell carboxylated particles were, respectively, investigated with the aim of producing latex?protein complexes to be used in immunoagglutination assays able to detect the leptospirosis disease in either humans or animals. To this effect, a protein lysate of crude extracts was evaluated, and sensitizations were carried out at different pHs, with the antigenic proteins approach to the particle surface favored at pH close to their isoelectric point. In the covalent coupling experiments, high fractions of proteins were chemically bound to carboxyl groups on the particle surface and higher densities of linked proteins were obtained for particles exhibiting greater carboxyl group densities. The produced latex?protein complexes were tested in immunoagglutination assays, by turbidimetry and a visual method, from a panel that included positive and negative bovine, canine, and human sera. The area under receiver operating characteristic curves was used as an index of accuracy. The complexes obtained by covalent coupling of proteins on the latex of higher density of carboxyl groups allowed an acceptable discrimination between the studied positive and negative sera.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240537,"idioma_id":4,"titulo":"Development and assessment of a new cage-like particle adjuvant","resumen":"Objectives: To obtain and assess stable cage-like particles with low surface charge density, which can be prepared using a standardized, economic and scalable method. Methods: To form these nanoparticles, the lipid composition and proportion as well the method were modified in relation to cage-like particles previously described elsewhere. Bovine albumin was used to compare ISPA performance with that of other adjuvants in mice and to assess stability. Adjuvant efficacy was analysed using a mouse model of Trypanosoma cruzi infection, which shows protection against an intracellular infection that needs a strong cellular response. Key findings: The new particles were better in terms of level, kinetics and profile of humoral responses than Freund Adjuvant, aluminium hydroxide and Montanide TM ISA 206; they also tended to improve ISCOMATRIX? performance. Particle size and adjuvant performance were conserved during the 6-month period assessed after preparation. In the model of Trypanosoma cruzi infection, mice immunized with ISPA and trans-sialidase developed high protection. Conclusions: The obtained nanoparticles were stable and outperformed the other assessed adjuvants in joining together the capacity of most adjuvants to enhance the immune response against specific antigen, to reduce the number of doses, to homogenize the response between individuals and to reach a balanced TH1\/TH2 response.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240538,"idioma_id":4,"titulo":"Temperature responsive PEG-based polyurethanes &ldquo;&agrave; la carte&rdquo;","resumen":"Temperature responsive polymers able to alter their chemical or physical properties have been extensively investigated. Most of these polymers have an alkane polymer backbone with only carbon-carbon bonds. In this sense, the design of thermoresponsive polymers not only with sharp transition temperatures but also possessing hydrolizable linkages such as esters, carbonates or urethanes in the main backbone are highly desired. Here we show a library of thermoresponsive cationic and anionic polyurethanes synthesized by copolymerization of isophorone diisocyanate with poly(ethylene glycol) and ionic diols. These polyurethanes exhibit lower critical solution temperatures (LCST) that can be easily tuned from 20 °C to 60 °C by altering the polyurethane composition. Our findings show that LCST temperature could be reduced by the using poly(ethylene glycol) of lower molecular weight and\/or increasing the hydrophobicity of the employed ionic diol. We also demonstrated that the thermoresponsive behavior could be translated to hydrogels based on those ionic polyurethanes. These ?a la carte? thermoresponsive polyurethanes materials present a great potential in the biomedical field due to the presence of hydrolizable linkages in the main polymer backbone.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240539,"idioma_id":4,"titulo":"Development of a simple and economical diagnostic test for canine leishmaniasis","resumen":"Visceral leishmaniasis is a public health problem worldwide. The early diagnosis in dogs is crucial, since they are an epidemiologically relevant reservoir of the disease. The aim of a field study is to early identify the disease allowing rapid intervention to reduce its effects. We propose an immunoagglutination test as a visual in situ method for diagnosis of canine visceral leishmaniasis. Latex-protein complexes were sensitized by covalent coupling of a chimeric recombinant antigen of Leishmania spp. onto polystyrene latex with carboxyl functionality. The reaction time and the antigen concentration under which the immunoagglutination assay shows greater discrimination between the responses of a positive control serum and a negative control serum were determined. Then, the latex-protein complexes were evaluated as a visual diagnostic tool with a panel of 170 sera. The test may be read between 2 and 5 min and can be performed even using sera with elevated concentration of lipids, bilirubin or with variable percentage of hemolysis. The sensitivity, the specificity and the diagnostic accuracy were 78%; 100% and >80%, respectively. The visual immunoagglutination test is of potential application as a method for field studies because it shows results in less than 5 min, it is easy to implement and does not require sophisticated equipment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240544,"idioma_id":5,"titulo":"A&P PERIÓDICO #4 - 2017 - 'Consultorio Psico'","resumen":"CONSULTORIO P.sicOPantalla de Espesor Estructural: (...en la panza de una ballena)El encargo consistió en recuperar una obra ya empezada y definir un consultorio de psicología con carácter urbano que permita desarrollar también un pequeño departamento en el nivel superior. El lugar?una esquina de los grandes y antiguos contenedores espaciales existentes en el sector? y el recorte de una pequeña porción dentro de uno de estos galpones comerciales, ya deteriorado, y de pertenencia familiar con salida por calle Moreno.La operación a realizar? un trabajo de reforma interna concentrado en la sustracción y el encuentro de una geometría con espesor? un pequeño espacio extraído desde lo más interno de este gran vacío.Al estar construida la losa y escalera a planta alta solo quedaba definir el doble ingreso y concentrar el esfuerzo en la fachada como única entrada de luz posible. Para lograr una fachada recortada en estos grandes y antiguos muros era necesario pensar una estructura adintelada y autoportante? así se llego a definir una malla conformada por tabiques de hormigón armado, que transfiere al frente un espesor espacial. Capaz de resolver la protección solar, conjunto a la contención de las aberturas de madera previstas. Atrapando el recorrido del sol en orientación norte esta estructura permite estirar la luz hasta el fondo del local, así se consigue un borde con dimensión para el descanso y la lectura'acompañando aberturas internas, muros bajos y recortes de piso en losa, se consigue una sensación extendida de iluminación y ventilación interna, recuperada en la búsqueda de un  exterior que evite el encierro? ??una cuña de vacío que retiene esa acción tan propia de quien asciende a la superficie por una bocanada de aire?.estudio 906Autor:Arq. Juan C. BaimaColaborador:Matías YrigoyIng. Ezequiel Blatter (calculo estructura)Título:Consultorio PsicoUbicación:Moreno 1125, San José de la Esquina, Santa Fe.Fecha realización:2013 - 2015","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240546,"idioma_id":5,"titulo":"Animaciones, vídeos y códigos: herramientas para mejorar la comprensión de conceptos científicos","resumen":"Este escrito muestra parte de lo producido en el marco de la investigación que engloba desarrollo, uso y evaluación de herramientas tecnológicas para el aprendizaje de conceptos de química para primer año de ingeniería en la universidad y de matemática para el último año del secundario. Por un lado se generó una animación referida a Equilibrio Químico para favorecer el aprendizaje de contenidos abstractos y se evaluó el impacto producido. Por el otro, se produjeron vídeos con clases grabadas y guías de estudio incorporando códigos de respuesta rápida. La metodología utilizada para recoger datos fue una combinación de encuestas con preguntas abiertas y cerradas, y técnica focusgroup. Los resultados muestran que la animación logró desarrollar una mejor comprensión de conceptos y generó mayor disposición para el aprendizaje. Los estudiantes secundarios rescatan grabación de clases, e implementación de códigos, más no consideran al aula virtual como herramienta de comunicación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240550,"idioma_id":4,"titulo":"PKA role in translational response to heat stress in Saccharomyces cerevisiae.","resumen":"Cellular response to stress conditions using different mechanisms such as translation arrest and transient relocation of untranslated mRNAs to ribonucleic practicles (mRNPs) known as stress granules (SGs) and processing bodies (PBs). Previously, we demonstrate that  cAMP dependent Protein Kinase (PKA) is involved in multiple steps of translation regulation in response to nutrient availability. In Saccharoymeces cerevisiae there is one gene that encodes for the regulatory subunit (BCY1) and three that encode for the catalytic isoforms (TPK1, TPK2 and TPK3). Here, we examine the role of PKA in heat shock response. In response to heat stress severity, nuclear-cytoplasmic relocalization of each PKA catalytic subunit was observed. Mild heat stress induces the aggregation of Tpk3 and promotes the aggregation of closed mRNA loop complexes into SGs. Severe heat stress leads to the formation of PBs and SGs that contain Tpk2 and Tpk3 and directs the accumulation and aggregation of the initiation translation complex 48S. Tpk1 showed mostly cytoplasmic localization. Analysis of mRNP dynamic, translational arrest and translational fitness of CYC1, HSP42, HSP30 and ENO2 gene whose tranlational fitness is regulated by heat stress showed that TPK3 or TPK2 deletion affects the translational response to severe heat stress. TPK2 deletion leads to strong translational arrest, an increment in mRNP agreggation and the translational hypersensitivity to heat stress. TPK3 deletion inhibits mRNP formation as well as translational arrest and affected the translational response of analyzed genes. Therefore, our results provide evidence that Tpk2 and Tpk3 would have opposite role on heat stress translational adaptation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240552,"idioma_id":5,"titulo":"?El pasado es nuestro futuro? memoria y arqueología en 'El Antigal' de San Pedro","resumen":"En este trabajo reflexionamos sobre las prácticas y sentidos movilizados en torno a los materiales arqueológicos que integran las colecciones del Centro de Interpretación Indígena ?El Antigal? (San Pedro, Provincia de Buenos Aires), gestionado por la comunidad Lma Iacia Qom. Desde el año 2009 este espacio nuclea a miembros de la comunidad que realizan una serie de actividades dirigidas a conservar y expresar la cultura indígena, articulando la investigación y rescate de su historia con los reclamos por autoreconocimiento y fortalecimiento de la identidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240558,"idioma_id":4,"titulo":"Sakacin G is the main responsible bacteriocin for the anti-listerial activity of meat-borne Lactobacillus curvatus ACU-1","resumen":"p { margin-bottom: 0.25cm; direction: ltr; line-height: 120%; text-align: left; }p.western { font-size: 12pt; }p.cjk { font-family: 'Noto Sans CJK SC Regular'; font-size: 12pt; }p.ctl { font-family: 'FreeSans'; font-size: 12pt; }a:link { color: rgb(0, 0, 255); }The present study was conducted to quantify theexpression of the sakacins produced by Lactobacilluscurvatus ACU-1, a strain isolated fromartisanal dry fermented sausages of Argentina.Polymerase chain reaction (PCR) screeningindicated the presence of sakacin G, P and Q genes in L.curvatus ACU-1. Purification andactivity assays determined that anti-Listeriaactivity was mainly associated to sakacin G, as mass spectrometryanalysis revealed a single peak of 3,832.60 Da. Furthercharacterization by quantitative PCR demonstrated that L.curvatus ACU-1 transcription of sakacinG structural gene was three orders of magnitude higher than theothers. Interestingly, L.curvatus ACU-1 had skgA1\/skgA2as well as sppQgenes encoded in a plasmid, while sppAgene that encodes for sakacin P, was present in the bacterialchromosome. These results point out that sakacin G is the mainpeptide responsible for the anti-listerial activity of L.curvatus ACU-1, with little or nocontribution of sakacin P and sakacin Q.The high level of expression of sakacin Gdemonstrated in the present work would facilitate its potential usein food preservation improving the food quality, safety and shelflife. In addition, the sakacin G promoter may serve as an interestingtool for the expression of other bacteriocins at higher levels.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240559,"idioma_id":4,"titulo":"Nisin Z produced by Lactococcus lactis from bullfrog hatchery is active against Citrobacter freundii, a red-leg syndrome related pathogen","resumen":"p { margin-bottom: 0.25cm; line-height: 120%; }Lactococcus lactissubsp. lactis CRL 1584 isolated from a bullfrog hatchery produces abacteriocin that inhibits both indigenous Citrobacter freundii (aRed-Leg Syndrome related pathogen) and Lactobacillus plantarum, andListeria monocytogenes as well. Considering that probiotics requireshigh cell densities and\/or bacteriocin concentrations, the effect ofthe temperature on L. lactis growth and bacteriocin production wasevaluated to find the optimal conditions. Thus, the growth rate wasmaximal at 36 °C, whereas the highest biomass and bacteriocinactivity was achieved between 20 and 30 °C and 20?25 °C,respectively. The bacteriocin synthesis was closely growth associatedreaching the maximal values at the end of the exponential phase.Since bacteriocins co-production has been evidenced in bacterialgenera, a purification of the bacteriocin\/s from L. lactis culturesupernatants was carried out. The active fraction was purified bycationic-exchange chromatography and then, a RP-HPLC was carried out.The purified sample was a peptide with a 3353.05 Da, a molecular massthat matches nisin Z, which turned out to be the only bacteriocinproduced by L. lactis CRL 1584. Nisin Z showed bactericidal effect onC. freundii and L. monocytogenes, which increased in the presencel-lactic acid + H2O2. This is the first report on nisin Z productionby L. lactis from a bullfrog hatchery that resulted active on aGram-negative pathogen. This peptide has potential probiotic forraniculture and as food biopreservative for bullfrog meat.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240560,"idioma_id":4,"titulo":"Application of MCR-ALS to reveal intermediate conformations in the thermally induced &alpha;-&beta; transition of poly- l -lysine monitored by FT-IR spectroscopy","resumen":"Temperature-induced conformational transitions of poly-l-lysine were monitored with Fourier-transform infrared (FT-IR) spectroscopy between 10 °C and 70 °C. Chemometric analysis of dynamic IR spectra was performed by multivariate curve analysis?alternating least squares (MCR-ALS) of the amide I&#8242; and amide II&#8242; spectral region. With this approach, the pure spectral and concentration profiles of the conformational transition were obtained. Beside the initial &#945;-helical, the intermediate random coil\/extended helices and the final &#946;-sheet structure, an additional intermediate PLL conformation was identified and attributed to a transient &#946;-sheet structure.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240561,"idioma_id":4,"titulo":"Determination of six veterinary pharmaceuticals in egg by liquid chromatography: chemometric optimization of a novel air assisted-dispersive liquid-liquid microextraction by solid floating organic drop","resumen":"Two extraction strategies for albendazole, chloramphenicol, trimethoprim, enrofloxacin, oxitetracycline and nicarbazin in egg were optimized for its quantitation by liquid chromatography. First, to find out the optimized condition for the air assisted-dispersive liquid-liquid microextraction based on solidification of organic drop, two designs were built: a fractional factorial and a central composite design. The optimum conditions resulted 1140 µL of water, 125 mg of ZnSO4, 1175 µL of acetonitrile, 1200 µL of methanol and 740 µL of acetone, using 1.00 g of homogenized egg and 50 µL of 1-dodecanol. Second, two designs were also built to optimize the dispersive liquid-liquid microextraction: a central composite and a mixture designs to set the combination of the re-suspended solvents. The optimum conditions resulted 1840 &#956;L of acetonitrile and 160 &#956;L of dichloromethane and the re-suspended mixture of acetonitrile and sodium phosphate buffer 10 mmol L?1 pH = 3.50 (30:70 v\/v).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240563,"idioma_id":4,"titulo":"Open-source Assisted Laboratory Automation through Graphical User Interfaces and 3D Printers. Application to Equipment Hyphenation for Higher-order data Generation","resumen":"Higher-order data generation implies some automation challenges, which are mainly related to the hidden programming languages and electronic details of the equipment. When techniques and\/or equipment hyphenation are the key to obtaining higher-order data, the required simultaneous control of them demands funds for new hardware, software, and licenses, in addition to very skilled operators. In this work, we present Design of Inputs-Outputs with Sikuli (DIOS), a free and open-source code program that provides a general framework for the design of automated experimental procedures without prior knowledge of programming or electronics. Basically, instruments and devices are considered as nodes in a network, and every node is associated both with physical and virtual inputs and outputs. Virtual components, such as graphical user interfaces (GUIs) of equipment, are handled by means of image recognition tools provided by Sikuli scripting language, while handling of their physical counterparts is achieved using an adapted open-source three-dimensional (3D) printer. Two previously reported experiments of our research group, related to fluorescence matrices derived from kinetics and high-performance liquid chromatography, were adapted to be carried out in a more automated fashion. Satisfactory results, in terms of analytical performance, were obtained. Similarly, advantages derived from open-source tools assistance could be appreciated, mainly in terms of lesser intervention of operators and cost savings. (Figure Presented).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240565,"idioma_id":4,"titulo":"New insights into enterocin CRL35; mechanism of action and immunity revealed by heterologous expression in Escherichia coli","resumen":"The role of the class IIa bacteriocin membrane receptor protein remains unclear and two different mechanisms have been proposed: the bacteriocin could interact with the receptor changing it to an open conformation or the receptor might act as an anchor allowing subsequent bacteriocin insertion and membrane disruption. Bacteriocin-producing cells synthesize an immunity protein that forms an inactive bacteriocin-receptor-immunity complex. To better understand the molecular mechanism of enterocin CRL35, the peptide was expressed as the suicidal probe EtpM-enterocin CRL35 in Escherichia coli, a naturally insensitive microorganism since it does not express the receptor. When the bacteriocin is anchored to the periplasmic face of the plasma membrane through the bitopic membrane protein, EtpM, E. coli cells depolarize and die. Moreover, co-expression of the immunity protein prevents the deleterious effect of EtpM-enterocin CRL35. The binding and anchoring of the bacteriocin to the membrane has demonstrated to be a sufficient condition for its membrane insertion. The final step of membrane disruption by EtpM-enterocin CRL35 is independent from the receptor, which means that the mannose PTS might not be involved in the pore structure. In addition, the immunity protein can protect even in the absence of the receptor.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240567,"idioma_id":4,"titulo":"Solvatomorphs of 25,26,27,28- tetrahydroxycalix[4]arene and 5,11,17,23-tetramino-25,26,27,28-tetrabutoxycalix[4]arene: quenching photoluminescence through switching the guest","resumen":"Here we have disclosed two solid state forms of 5,11,17,23-tetramino-25,26,27,28-tetrabutoxycalix[4]arene (1) and two onesof the non-functionalized 25,26,27,28- tetrahydroxycalix[4]arene(2). This is the first structural knowledge of a tetra-aminofunctionalized calixarene derivative, even though this compoundis well known and used as precursor of several otherfunctionalized calix[4]arenes. The two solid forms of 1 differ bypresence of either water or water\/dimethylsulfoxide (DMSO)solvent molecules entrapped into the major calixarene cavity,even though pinched conformation is adopted in both forms as aconsequence of contacts between solvent molecules and phenylrings. Likewise, the switch of water for DMSO into cone cavity of 1has abrogated photoluminescence (PL) found only in the dihydrateform. Frontier molecular orbitals calculations at the B3LYP\/6-31G*level of theory support a short-range electron transfer betweenguest (DMSO) and host (1) molecules quenching the solid statephotoluminescence whether DMSO is entrapped into the cone.This solvatomorphism approach for PL search in calixarenes opensperspective of tuning and even increasing this performance ofcalixarenes through changing the guest solvent molecule.Similarly, the two crystal forms of 2 entrap either methyl alcoholor DMSO into its cone, which, as well as both crystal forms of 1,have packed into sheets through different fashions and contactspattern","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240568,"idioma_id":4,"titulo":"Mechanistic insight into the acid-catalyzed isomerization of biomass-derived polysubstituted pyrrolidines: an experimental and DFT study","resumen":"The 1,3-dipolar cycloaddition reactions of azomethine ylides is one of the preferred methods for the synthesis of polysubstituted pyrrolidines. The use of chiral dipolarophiles derived from carbohydrates yields enantiomerically pure pyrrolidines, usually in good to excellent endo selectivities, along with otherminor stereoisomers. Recently, we found an unusual isomerization event that allowed the isolation of useful pyrrolidines with relative stereochemistries difficult to obtain otherwise. Although a simple and efficient protocol to promote these transformations was developed, the mechanism was not fully unravelled. Herein, after a combination of experimental, spectroscopic and computational studies (using DFT methods) we propose that this isomerization event takes place through a retro-Mannich\/\/Mannich cascade, via the formation of an iminium ion with E geometry.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240569,"idioma_id":4,"titulo":"Sphaerialactonam, a gamma-lactam-isochromanone from the Hawaiian endophytic fungus Paraphaeosphaeria sp. FT462","resumen":"Reinvestigation of the endophytic fungus Paraphaeosphaeria sp. FT462 from the Hawaiian plant Lycopodiella cernua (L.) Pic. Serm led to the isolation and identification of a unique gamma-lactamisochromanone (1). The structure of 1 was determined by NMR, MS spectroscopic analysis, and quantum chemical calculations of NMR. The compound was tested inactive against A2780 and A2780cisR.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240570,"idioma_id":4,"titulo":"Experimental and Theoretical Second Harmonic Generation and Photoluminescence from the Pseudo-Centrosymmetric Dihydrochloride Salt Dihydrate of trans-1,2-bis(4-pyridyl)ethane","resumen":"Here we have prepared a dihydrochloride salt dihydrate of the well-known trans-1,2-bis(4-pyridyl)ethene (BPE) featuring both photoluminescent and nonlinear optical properties. In its triclinic lattice (space group P1), BPE cations are face-to-tail stacked through &#960;?&#960;interactions between the spacer double-bonded carbons and the protonated pyridyl ring, with a slippage of 3.45 Å always  towards the same direction, which is common in other NLO crystals. Theexistence of inversion symmetry was suggested in its crystal structure, which was ruled out by the SHG emission centred at 487 nm upon excitation at 974 nm. While the fully optimized single molecule of the divalent BPE cation in thegas phase had almost null µ, &#946; tot, &#946; CT and &#946;vec values calculated at the CAM-B3LYP\/NLO-V\/\/B3LYP\/6-31G* level of theory, these values have differed from zero in the crystal conformation. More interestingly, a ca. 4-fold increase in&#946;tot, &#945; and µ was observed for the &#960;...&#960; stacked four molecules as found in its crystal structure. At last, this BPE material presents high photoluminescence emission centred at 425 nm under excitation at 366 nm, being therefore amultifunctional optical crystal form.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240571,"idioma_id":4,"titulo":"Verbenanone, an octahydro-5H-chromen-5-one from a Hawaiian-Plant Associated Fungus FT431","resumen":"A new secondary metabolite verbenanone (1) with a unique (4aS,8aS)-octahydro-5Hchromen-5-one moiety has been obtained from the endophytic fungus FT431, which was isolated from the native Hawaiian plant Verbena sp. The structure of compound 1 was characterized based on NMR and MS spectroscopic analysis. The absolute configuration (AC) of compound 1 was determined by Mosher acids. Compound 1 was tested against A2780 and A2780cisR, but it was inactive.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240572,"idioma_id":4,"titulo":"A New N-methoxypyridone from the Co-Cultivation of Hawaiian Endophytic Fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062","resumen":"A new N-methoxypyridone analog (1), together with four known compounds, was isolated from the co-culture of Hawaiian endophytic fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062. The structure of the new compound was elucidated as 11S-hydroxy-1-methoxyfusaricide (1) by extensive spectroscopic analysis and comparison with the literature. The absolute configuration of1 was determined by comparison with the experimental and calculated ECD spectra. The absolute configuration of compound 3 was investigated and renamed as (+)-epipyridone by comparison of the optical rotation and CD spectrum with those of 1. The other known compounds were identified as epicoccarine B (2), D8646-2-6 (4), and iso-D8646-2-6 (5). Compounds 4 and 5 showed modest inhibitory activity towards pathogenic fungi. Epicoccarine B (2) inhibited A2780 and TK-10 with an IC50 value of 22 µM.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240573,"idioma_id":4,"titulo":"Catalytic Asymmetric Synthesis and Stereochemical Revision of (+)-Cryptoconcatone H","resumen":"The total synthesis and structural revision of (+)-cryptoconcatone H is described. Guided by computational studies for the final structure assignment, the stereogenic centers at the tetrahydropyran moiety of (+)-cryptoconcatone H were assembled through catalytic asymmetric methodologies: Krische allylation, CM reaction and THP formation via Pd(II)-catalyzed cyclization. Finally, Krische allylation reaction established the last stereocenter and the lactone moiety was formed by RCM.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240574,"idioma_id":4,"titulo":"NF-KB inhibitors, unique gamma-pyranol-gamma-lactams with sulfide and sulfoxide moieties from Hawaiian plant Lycopodiella cernua derived fungus Paraphaeosphaeria neglecta FT462","resumen":"LC-UV\/MS-based metabolomic analysis of the Hawaiian endophytic fungus Paraphaeosphaeria neglecta FT462 led to the identification of four unique mercaptolactated &#947;-pyranol?&#947;-lactams, paraphaeosphaerides E?H (1?4) together with one &#947;-lactone (5) and the methyl ester of compound 2 (11). The structures of the new compounds (1?5 and 11) were elucidated through the analysis of HRMSand NMR spectroscopic data. The absolute configuration was determined by hemical reactions with sodium borohydride, hydrogen peroxide, &#945;- methoxy-&#945;-trifluoromethyl)phenylacetyl chlorides (Mosher reagents), and DP4 + NMR calculations. All the compounds were tested against STAT3, A2780 and A2780cisR cancer cell lines, E. coli JW2496, and NF-kB. Compounds 1 and 3 strongly inhibited NF-kB with IC50 values of 7.1 and 1.5 &#956;M, respectively.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240575,"idioma_id":4,"titulo":"Winged-Cone Conformation in Hexa-p&#8209;tert-butylcalix[6]arene Driven by the Unusually Strong Guest Encapsulation","resumen":"Hexa-p-tert-butylcalix[6]arene (1) is believed to adopt a winged conformation in a solution, featured by four phenyl rings perpendicular to the calix basis and two others at 1,4-positions lying down. However, there is some controversyon the occurrence of this conformation because it has never been found in the solid state of calix[6]arenes, regardless of the substitution pattern at lower and upper rims. Here, we have observed the winged-cone conformation for the first time in a solvate form of 1 with dimethyl sulfoxide (DMSO), dimethylformamide, and pyridine. The DMSO molecule is strongly encapsulated into 1 through two OH···O hydrogen bonds with both flattened phenolic moieties, one lp(S)···&#960; and four CH···&#960; interactions with the four perpendicular phenyl rings. This host&#8722;guest complex has energy lower by 23.4 kcal mol&#8722;1 than the isolated species. In addition, another DMSO solvate form with 1,2,3-alternate conformation was also obtained in this study, and its structure is compared with that of the precedent one. A detailed density functional theory study has also been carried out to understand the energetic relationships among cone conformers, intramolecular hydrogen-bonding patterns, and DMSO encapsulation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240576,"idioma_id":4,"titulo":"Heliotropiumides A and B, new phenolamides with N-carbamoyl putrescine moiety from Heliotropium foertherianum collected in Hawaii and their biological activities","resumen":"Two new compounds heliotropiumides A (1) and B (2), phenolamides each with an uncommon carbamoyl putrescine moiety, were isolated from the seeds of a naturalized Hawaiian higher plant, Heliotropium foertherianum Diane & Hilger in the borage family, which is widely used for the treatment of ciguatera fish poisoning. The structures of compounds 1 and 2 were characterized based on MS spectroscopic and NMR analysis, and DP4+ calculation. The absolute configuration (AC) of compound 1 was determined by comparison of its optical rotation with those reported in literature. Compound 2 showed inhibition against NF-&#954;B with an IC50value of 36 &#956;M.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240578,"idioma_id":4,"titulo":"Solvatomorphs of 25,26,27,28- tetrahydroxycalix[4]arene and 5,11,17,23-tetramino-25,26,27,28-tetrabutoxycalix[4]arene: quenching photoluminescence through switching the guest","resumen":"Here we have disclosed two solid state forms of 5,11,17,23-tetramino-25,26,27,28-tetrabutoxycalix[4]arene (1) and two onesof the non-functionalized 25,26,27,28- tetrahydroxycalix[4]arene(2). This is the first structural knowledge of a tetra-aminofunctionalized calixarene derivative, even though this compoundis well known and used as precursor of several otherfunctionalized calix[4]arenes. The two solid forms of 1 differ bypresence of either water or water\/dimethylsulfoxide (DMSO)solvent molecules entrapped into the major calixarene cavity,even though pinched conformation is adopted in both forms as aconsequence of contacts between solvent molecules and phenylrings. Likewise, the switch of water for DMSO into cone cavity of 1has abrogated photoluminescence (PL) found only in the dihydrateform. Frontier molecular orbitals calculations at the B3LYP\/6-31G*level of theory support a short-range electron transfer betweenguest (DMSO) and host (1) molecules quenching the solid statephotoluminescence whether DMSO is entrapped into the cone.This solvatomorphism approach for PL search in calixarenes opensperspective of tuning and even increasing this performance ofcalixarenes through changing the guest solvent molecule.Similarly, the two crystal forms of 2 entrap either methyl alcoholor DMSO into its cone, which, as well as both crystal forms of 1,have packed into sheets through different fashions and contactspattern","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240579,"idioma_id":4,"titulo":"Mechanistic insight into the acid-catalyzed isomerization of biomass-derived polysubstituted pyrrolidines: an experimental and DFT study","resumen":"The 1,3-dipolar cycloaddition reactions of azomethine ylides is one of the preferred methods for the synthesis of polysubstituted pyrrolidines. The use of chiral dipolarophiles derived from carbohydrates yields enantiomerically pure pyrrolidines, usually in good to excellent endo selectivities, along with other minor stereoisomers. Recently, we found an unusual isomerization event that allowed the isolation of useful pyrrolidines with relative stereochemistries difficult to obtain otherwise. Although a simple and efficient protocol to promote these transformations was developed, the mechanism was not fully unravelled. Herein, after a combination of experimental, spectroscopic and computational studies (using DFT methods) we propose that this isomerization event takes place through a retro-Mannich\/\/Mannich cascade, via the formation of an iminium ion with E geometry.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240580,"idioma_id":4,"titulo":"Sphaerialactonam, a gamma-lactam-isochromanone from the Hawaiian endophytic fungus Paraphaeosphaeria sp. FT462","resumen":"Reinvestigation of the endophytic fungus Paraphaeosphaeria sp. FT462 from the Hawaiian plant Lycopodiella cernua (L.) Pic. Serm led to the isolation and identification of a unique gamma-lactamisochromanone (1). The structure of 1 was determined by NMR, MS spectroscopic analysis, and quantum chemical calculations of NMR. The compound was tested inactive against A2780 and A2780cisR.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240581,"idioma_id":4,"titulo":"Experimental and Theoretical Second Harmonic Generation and Photoluminescence from the Pseudo-Centrosymmetric Dihydrochloride Salt Dihydrate of trans-1,2-bis(4-pyridyl)ethane","resumen":"Here we have prepared a dihydrochloride salt dihydrate of the well-known trans-1,2-bis(4-pyridyl)ethene (BPE) featuring both photoluminescent and nonlinear optical properties. In its triclinic lattice (space group P1), BPE cations are face-to-tail stacked through &#960;?&#960;interactions between the spacer double-bonded carbons and the protonated pyridyl ring, with a slippage of 3.45 Å always  towards the same direction, which is common in other NLO crystals. Theexistence of inversion symmetry was suggested in its crystal structure, which was ruled out by the SHG emission centred at 487 nm upon excitation at 974 nm. While the fully optimized single molecule of the divalent BPE cation in thegas phase had almost null µ, &#946; tot, &#946; CT and &#946;vec values calculated at the CAM-B3LYP\/NLO-V\/\/B3LYP\/6-31G* level of theory, these values have differed from zero in the crystal conformation. More interestingly, a ca. 4-fold increase in&#946;tot, &#945; and µ was observed for the &#960;...&#960; stacked four molecules as found in its crystal structure. At last, this BPE material presents high photoluminescence emission centred at 425 nm under excitation at 366 nm, being therefore amultifunctional optical crystal form.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240582,"idioma_id":4,"titulo":"Verbenanone, an octahydro-5H-chromen-5-one from a Hawaiian-Plant Associated Fungus FT431","resumen":"A new secondary metabolite verbenanone (1) with a unique (4aS,8aS)-octahydro-5Hchromen-5-one moiety has been obtained from the endophytic fungus FT431, which was isolated from the native Hawaiian plant Verbena sp. The structure of compound 1 was characterized based on NMR and MS spectroscopic analysis. The absolute configuration (AC) of compound 1 was determined by Mosher acids. Compound 1 was tested against A2780 and A2780cisR, but it was inactive.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240583,"idioma_id":4,"titulo":"A New N-methoxypyridone from the Co-Cultivation of Hawaiian Endophytic Fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062","resumen":"A new N-methoxypyridone analog (1), together with four known compounds, was isolated from the co-culture of Hawaiian endophytic fungi Camporesia sambuci FT1061 and Epicoccum sorghinum FT1062. The structure of the new compound was elucidated as 11S-hydroxy-1-methoxyfusaricide (1) by extensive spectroscopic analysis and comparison with the literature. The absolute configuration of1 was determined by comparison with the experimental and calculated ECD spectra. The absolute configuration of compound 3 was investigated and renamed as (+)-epipyridone by comparison of the optical rotation and CD spectrum with those of 1. The other known compounds were identified as epicoccarine B (2), D8646-2-6 (4), and iso-D8646-2-6 (5). Compounds 4 and 5 showed modest inhibitory activity towards pathogenic fungi. Epicoccarine B (2) inhibited A2780 and TK-10 with an IC50 value of 22 µM.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240584,"idioma_id":4,"titulo":"Catalytic Asymmetric Synthesis and Stereochemical Revision of (+)-Cryptoconcatone H","resumen":"The total synthesis and structural revision of (+)-cryptoconcatone H is described. Guided by computational studies for the final structure assignment, the stereogenic centers at the tetrahydropyran moiety of (+)-cryptoconcatone H were assembled through catalytic asymmetric methodologies: Krische allylation, CM reaction and THP formation via Pd(II)-catalyzed cyclization. Finally, Krische allylation reaction established the last stereocenter and the lactone moiety was formed by RCM.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240585,"idioma_id":4,"titulo":"NF-KB inhibitors, unique gamma-pyranol-gamma-lactams with sulfide and sulfoxide moieties from Hawaiian plant Lycopodiella cernua derived fungus Paraphaeosphaeria neglecta FT462","resumen":"LC-UV\/MS-based metabolomic analysis of the Hawaiian endophytic fungus Paraphaeosphaeria neglecta FT462 led to the identification of four unique mercaptolactated &#947;-pyranol?&#947;-lactams, paraphaeosphaerides E?H (1?4) together with one &#947;-lactone (5) and the methyl ester of compound 2 (11). The structures of the new compounds (1?5 and 11) were elucidated through the analysis of HRMSand NMR spectroscopic data. The absolute configuration was determined by hemical reactions with sodium borohydride, hydrogen peroxide, &#945;- methoxy-&#945;-trifluoromethyl)phenylacetyl chlorides (Mosher reagents), and DP4 + NMR calculations. All the compounds were tested against STAT3, A2780 and A2780cisR cancer cell lines, E. coli JW2496, and NF-kB. Compounds 1 and 3 strongly inhibited NF-kB with IC50 values of 7.1 and 1.5 &#956;M, respectively.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240586,"idioma_id":4,"titulo":"Winged-Cone Conformation in Hexa-p&#8209;tert-butylcalix[6]arene Driven by the Unusually Strong Guest Encapsulation","resumen":"Hexa-p-tert-butylcalix[6]arene (1) is believed to adopt a winged conformation in a solution, featured by four phenyl rings perpendicular to the calix basis and two others at 1,4-positions lying down. However, there is some controversyon the occurrence of this conformation because it has never been found in the solid state of calix[6]arenes, regardless of the substitution pattern at lower and upper rims. Here, we have observed the winged-cone conformation for the first time in a solvate form of 1 with dimethyl sulfoxide (DMSO), dimethylformamide, and pyridine. The DMSO molecule is strongly encapsulated into 1 through two OH···O hydrogen bonds with both flattened phenolic moieties, one lp(S)···&#960; and four CH···&#960; interactions with the four perpendicular phenyl rings. This host&#8722;guest complex has energy lower by 23.4 kcal mol&#8722;1 than the isolated species. In addition, another DMSO solvate form with 1,2,3-alternate conformation was also obtained in this study, and its structure is compared with that of the precedent one. A detailed density functional theory study has also been carried out to understand the energetic relationships among cone conformers, intramolecular hydrogen-bonding patterns, and DMSO encapsulation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240587,"idioma_id":4,"titulo":"Heliotropiumides A and B, new phenolamides with N-carbamoyl putrescine moiety from Heliotropium foertherianum collected in Hawaii and their biological activities","resumen":"Two new compounds heliotropiumides A (1) and B (2), phenolamides each with an uncommon carbamoyl putrescine moiety, were isolated from the seeds of a naturalized Hawaiian higher plant, Heliotropium foertherianum Diane & Hilger in the borage family, which is widely used for the treatment of ciguatera fish poisoning. The structures of compounds 1 and 2 were characterized based on MS spectroscopic and NMR analysis, and DP4+ calculation. The absolute configuration (AC) of compound 1 was determined by comparison of its optical rotation with those reported in literature. Compound 2 showed inhibition against NF-&#954;B with an IC50value of 36 &#956;M.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240588,"idioma_id":5,"titulo":"INDICADORES METABÓLICOS SANGUÍNEOS DE GENOTIPOS LECHEROS EN PASTOREO DE LA PROVINCIA DE NAPO-ECUADOR","resumen":"El objetivo de este trabajo fue evaluar el metabolismo energético\/proteico en sangre de vacas lecheras de cuatro genotipos de primera lactancia en condiciones de pastoreo en el cantón Arosemena Tola, Napo, Ecuador. Se evaluaron 36 vacas lecheras de primer parto cruzas de los genotipos: Bos Indicus x Gir (GIR), Bos Indicus x Brown Swiss (BS), Bos Indicus x Jersey (J) y Bos Indicus x Sahiwal (S). Se tomaron muestras de sangre de la vena coccígea los días 60 y 21 antes del parto, al momento del parto y a los 30, 60 y 90 días después del parto. Se determinaron los valores en plasma de, glucosa, urea, creatinina y proteínas totales. Ninguna de las variables presentó diferencias significativas (p&#8805;0,05) entre razas y los valores obtenidos para todos se encontraron por debajo de los valores normales para las vacas lecheras. La glucosa no mostró diferencias significativas (p&#8805;0,05) en el tiempo. En cambio, para Urea, Creatinina y Proteínas Totales existieron diferencias significativas (p&#8805;0,001) a través del tiempo. Utilizando una regresión local con parámetro de suavizado igual a 0,8 para estudiar cómo era la trayectoria de la variable en el tiempo. Luego, seajustó un modelo lineal mixto para cada variable, considerando un nodo en los casos para los cuales se observaba un cambio en la trayectoria en algún tiempo en particular (según lo observado en el gráfico 1, 2 y 3 de la regresión local).Se concluye que para los cuatro genotipos lecheros estudiados no se encontró diferencias en la concentración de los indicadores metabólicos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240589,"idioma_id":4,"titulo":"Bioprospection of cold-adapted yeasts with biotechnological potential from Antarctica","resumen":"The aim of this study was to investigate the ability to produce extracellular hydrolytic enzymes at low temperature of yeasts isolated from 25 de Mayo island, Antarctica, and to identify those exhibiting one or more of the evaluated enzymatic activities. A total of 105 yeast isolates were obtained from different samples and 66 were identified. They belonged to 12 basidiomycetous and four ascomycetous genera. Most of the isolates were ascribed to the genera Cryptococcus, Mrakia, Cystobasidium, Rhodotorula, Gueomyces, Phenoliferia, Leucosporidium, and Pichia. Results from enzymes production at low temperatures revealed that the Antarctic environment contains metabolically diverse cultivable yeasts, which represent potential tools for biotechnological applications. While most the isolates proved to produce 2-4 of the investigated exoenzymes, two of them evidenced the six evaluated enzymatic activities: Pichia caribbica and Guehomyces pullulans, which were characterized as psycrotolerant and psycrophilic, respectively. In addition, P. caribbica could assimilate several n-alkanes and diesel fuel. The enzyme production profile and hydrocarbons assimilation capacity, combined with its high level of biomass production and the extended exponential growth phase make P. caribbica a promising tool for cold environments biotechnological purposes in the field of cold-enzymes production and oil spills bioremediation as well.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240590,"idioma_id":4,"titulo":"Phenol degradation and heavy metal tolerance of Antarctic yeasts","resumen":"In cold environments, biodegradation of organic pollutants and heavy metal bio-conversion requires the activity of cold-adapted or cold-tolerant microorganisms. In this work, the ability to utilize phenol, methanol and n-hexadecane as C source, the tolerance to different heavy metals and growth from 5 to 30&#8201;°C were evaluated in cold-adapted yeasts isolated from Antarctica. Fifty-nine percent of the yeasts were classified as psychrotolerant as they could grow in all the range of temperature tested, while the other 41% were classified as psychrophilic as they only grew below 25&#8201;°C. In the assimilation tests, 32, 78, and 13% of the yeasts could utilize phenol, n-hexadecane, and methanol as C source, respectively, but only 6% could assimilate the three C sources evaluated. In relation to heavy metals ions, 55, 68, and 80% were tolerant to 1&nbsp;mM of Cr(VI), Cd(II), and Cu(II), respectively. Approximately a half of the isolates tolerated all of them. Most of the selected yeasts belong to genera previously reported as common for Antarctic soils, but several other genera were also isolated, which contribute to the knowledge of this cold environment mycodiversity. The tolerance to heavy metals of the phenol-degrading cold-adapted yeasts illustrated that the strains could be valuable as inoculant for cold wastewater treatment in extremely cold environments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240591,"idioma_id":4,"titulo":"Bioremediation of hydrocarbon-contaminated soils in cold regions: Development of a pre-optimized biostimulation biopile-scale field assay in Antarctica","resumen":"Bioremediation proved to be an effective approach to deal with soil contamination, especially in isolated, cold environments such as Antarctica. Biostimulation, involving the addition of macronutrients -mainly nitrogen and phosphorous- is considered the simplest and cheapest bioremediation process. Optimizing the levels of these nutrients is a key step prior to the application of a biostimulation strategy. In this work, N and P levels, optimized by Response Surface Methodology (RSM) at lab-scale, were applied to an Antarctic hydrocarbon contaminated soil. The process was performed on-site, using high density polyethylene geomembranes (800&nbsp;&#956;m) to isolate treated soil from the surroundings and under environmental conditions at Carlini station (Antarctica) during 50&nbsp;days. Two 0.5&nbsp;ton biopiles were used as experimental units; a control biopile (CC), and a biostimulated system (BS), amended with N and P. At the end of the assay, hydrocarbon removal was significantly higher in BS system compared to CC (75.79% and 49.54% respectively), showing that the applied strategy was effective enough to perform a field-assay in Antarctica that significantly reduce soil contamination levels; and proving that RSM represents a fundamental tool for the optimization of nutrient levels to apply during bioremediation of fuel contaminated cold soils.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240596,"idioma_id":4,"titulo":"Prediction of severe toxicity in adult patients under treatment with 5-fluorouracil","resumen":"5-Fluorouracil (5-FU) has long been used for the treatment of gastrointestinal tumors harboring interindividual variability in both the pharmacokinetic and the pharmacogenetic profiles, which in turn may lead to life-threatening toxicities. We carried out a prospective cohort study of adult patients initiating treatment with 5-FU between 2013 and 2015. Primary exposures of interest were the methylenetetrahydrofolate reductase single nucleotide polymorphism in exons 4 and 7 and 5'-untranslated region-thymidylate synthase VNTR genotypes, in addition to baseline clinical and demographic variables. The primary outcome was the time to the occurrence of severe toxicity. We used a Cox regression model to evaluate patients' survival and toxicity experience and its association with baseline characteristics and a priori determined genetic polymorphisms. A total of 197 patients were included, 40.1% developed severe toxicity during follow-up. Variables that were significantly associated with developing severe toxicity were the European Organization for Research and Treatment of Cancer functional score [hazard ratio (HR): 0.98; 95% confidence interval (CI): 0.97-0.99]; type of tumor [anus (HR: 2.50; 95% CI: 1.07-5.82), head and neck\/esophagus\/stomach (HR: 2.95; 95% CI: 1.64-5.33)] and 5-FU continuous infusion regimens over 4-5 days (HR: 9.35; 95% CI: 2.68-32.59). We found a significant association between baseline functional status, type of tumor and continuous infusion regimens and the occurrence of severe toxicity during the follow-up of patients receiving 5-FU. No association was found with the genotypic variants evaluated. Future validation and modeling of an everyday easy-to-use score to predict toxicity among these subgroup of patients remains warranted","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240597,"idioma_id":4,"titulo":"Prevalence of thymidylate synthase gene 5'-untranslated region variants in an Argentinean sample","resumen":"Thymidylate synthase (TYMS) is a key enzyme in nucleotide synthesis and therefore, an important target of many chemotherapeutic agents. Expression of TYMS mRNA is thought to be modulated by a 28-bp tandem repeat polymorphism within its 5´-untranslated region, raising the question of this variant´s utility in predicting the efficacy and toxicity of cancer treatment regimens. The aim of the present research was to describe the distribution of this TYMS polymorphism in the Argentinean population. A total of 199 randomly selected DNA samples from healthy volunteers were analyzed using polymerase chain reaction and polyacrylamide gel electrophoresis. The 2R and 3R alleles were present in 47.74 and 52.26% of samples, respectively, with frequencies of 21.6 (43), 52.3 (104), and 26.1% (52) recorded for the 2R\/2R, 2R\/3R, and 3R\/3R genotypes, respectively. No significant difference regarding gender was observed. Our prevalence data are similar to those reported for other Caucasian populations. This opens a discussion concerning the reference population valid for comparisons and the clinical importance of this genotyping test as an additional tool in personalized medicine.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240598,"idioma_id":5,"titulo":"Las bases conceptuales de los derechos humanos","resumen":"Los derechos humanos, como discurso de la dignidad humana, han sido históricamente identificados con la naturaleza humana y calificados como innatos, universales, imprescriptibles e inderogables. Sin embargo, las conquistas más sustanciosas de nuestros tiempos demuestran que solo desde una perspectiva crítica es posible desafiar a las estructuras teóricas tradicionales y conservadoras. En efecto, resulta imperioso colocar el énfasis en los necesarios debates que deben librarse alrededor del concepto y los fundamentos de los derechos humanos, incluso desde la propia óptica del Sistema Interamericano de Protección.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240600,"idioma_id":4,"titulo":"Neotropical tree production: insights into germination, growth and outplanting for Maytenus boaria","resumen":"Knowledge about tree production practices is essential to support forestrestoration projects, but is still lacking for many tree species. Maytenus boaria is a neotropical tree distributed across the temperate and subtropical South American mountains. In central Argentina, it is mainly restricted to the most preserved forest remnants. Attempts to plant this species have had little success due to difficulties in seedling production and low seedlingsurvival. We set up four trials aiming to identify the constraints of seedling production and outplanting. Under greenhouse conditions, we evaluated (i) pre?germination treatments and (ii) seedling response to inoculation with arbuscular mycorrhizal fungi (AMF). In the field, we planted M. boaria saplings as well as saplings of the most abundant tree in our study site and recorded (iii) survival and height for 10 years. Finally, (iv) we quantified natural recruitmentin an attempt to determine M. boaria regeneration niche. Germination varied from 13.1 to 29.2% among treatments. Depulped seeds stratified at 5 oC showed the highest germination (29.2%). Shoot phosphorus concentration in AMF-treated seedlings was significantly higher (45%) than in non-inoculated seedlings. Survival of M. boaria saplings was similar to that of the most abundant tree in our study site, but their lower height suggested limited growth.We recorded low abundance of M. boaria seedlings in the field; therefore, we were unable to identify the characteristics of its regeneration niche. Reforestation activities should include seed depulping and stratification at 5 oC to improve germination. The capacity of AMF to enhance nutrition should be evaluated under field conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240601,"idioma_id":4,"titulo":"Design, synthesis and biological evaluation of 1,3-dihydroxyxanthone derivatives: Effective agents against acetylcholinesterase","resumen":"The present work concerns the rational design and development of new inhibitors of acetylcholinesterase (AChE) based on the privileged xanthone scaffold. In order to understand and rationalize the mode of action of these target structures a theoretical study was initially conducted. From the results of rational design, a new variety of amphiphilic xanthone derivatives were synthesized, structurally characterized and evaluated as potential anti-Alzheimer agents. The results showed that most of the synthesized compounds exhibited high AChE inhibitory activity at the micromolar range (IC50, 0.46?12.09 &#956;M). The synthetic xanthone 11 showed the best inhibitory effect on AChE and a molecular modeling study revealed that 11 targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. Therefore, this compound could be considered as a potential lead compound towards new drugs for the treatment of Alzheimer´s disease.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240603,"idioma_id":4,"titulo":"Studies on electrostatic interactions within model nano-confined aqueous environments of different chemical nature","resumen":"Abstract.: We study the potential of mean force for pairs of parallel flat surfaces with attractive electrostatic interactions by employing model systems functionalized with different charged, hydrophobic and hydrophilic groups. We study the way in which the local environment (hydrophobic or hydrophilic moieties) modulates the interaction between the attractive charged groups on the plates by removing or attracting nearby water and thus screening or not the electrostatic interaction. To explicitly account for the role of the solvent and the local hydrophobicity, we also perform studies in vacuo. Additionally, the results are compared to that for non-charged plates in order to single out and rationalize the non-additivity of the different non-covalent interactions. Our simulations demonstrate that the presence of neighboring hydrophobic groups promote water removal in the vicinity of the charged groups, thus enhancing charge attraction upon self-assembly. This role of the local hydrophobicity modulating electrostatic interactions is consistent with recent qualitative descriptions in the protein binding context. Graphical abstract: [Figure not available: see fulltext.].","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240604,"idioma_id":4,"titulo":"Selecting control sites for post-fire ecological studies using biological criteria and MODIS time series data","resumen":"Wildlandfires play a key role in the functioning and structure of vegetation. Theavailability of sensors aboard satellites, such as Moderate Resolution Imaging Spectroradiometer (MODIS), makespossible the construction of a time series of vegetation indices (VI) and themonitoring of post-fire vegetation recovery. One of the used techniques tomonitor post-fire vegetation is the comparison of a burned site with anadjacent unburned control site. However, to date, there is no objective methodavailable for selecting these unburned control sites. Here, we propose threebiological criteria that the unburned sites must meet to be considered controlsites, as well as statistical methods based on the analysis of the propertiesof the Quotient Vegetation Indices time series (QVI), to detect unburned sitesthat meet the proposed criteria. We also test the performance of the proposedmethod by checking the pre-firedifference between burned and unburned sites, assuming that thehigher the number of met criteria, the greater the similarity. Therefore, we compare the differences between VItime series of burned sites and VI time series of unburned sites with the same vegetationcover, that met three, two, one and none of the proposed criteria. In addition,we compare the quality of QVI time series that met three, two, one and none of the proposed criteria. Ourresults show that for NormalizedDifference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI) data, the difference betweenthe time series of burned and unburned sites gradually decrease with the increase of met criteria. A gradual increase is alsoobserved in the quality of the QVI time series with the increase of met criteria. Despite thelimitations present in the proposed method, our model represents an advancefrom the conceptual and methodological standpoints, since this is the firstproposal of a statistical method for selecting unburned control sites based onbiological criteria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240605,"idioma_id":4,"titulo":"Assessing wildfire exposure in the Wildland-Urban Interface area of the mountains of central Argentina","resumen":"Wildfires are a major threat to people and property in Wildland Urban Interface (WUI) communities worldwide, but while the patterns of the WUI in North America, Europe and Oceania have been studied before, this is not the case in Latin America. Our goals were to a) map WUI areas in central Argentina, and b) assess wildfire exposure for WUI communities in relation to historic fires, with special emphasis on large fires and estimated burn probability based on an empirical model. We mapped the WUI in the mountains of central Argentina (810,000 ha), after digitizing the location of 276,700 buildings and deriving vegetation maps from satellite imagery. The areas where houses and wildland vegetation intermingle were classified as Intermix WUI (housing density &gt; 6.17 hu\/km2 and wildland vegetation cover &gt; 50%), and the areas where wildland vegetation abuts settlements were classified as Interface WUI (housing density &gt; 6.17 hu\/km2, wildland vegetation cover &lt; 50%, but within 600 m of a vegetated patch larger than 5 km2). We generated burn probability maps based on historical fire data from 1999 to 2011; as well as from an empirical model of fire frequency. WUI areas occupied 15% of our study area and contained 144,000 buildings (52%). Most WUI area was Intermix WUI, but most WUI buildings were in the Interface WUI. Our findings suggest that central Argentina has a WUI fire problem. WUI areas included most of the buildings exposed to wildfires and most of the buildings located in areas of higher burn probability. Ourfindings can help focus fire management activities in areas of higher risk, and ultimately provide support for landscape management and planning aimed at reducing wildfire risk in WUI communities.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240606,"idioma_id":5,"titulo":"Detección de parcelas control para estudios ecológicos en áreas incendiadas: desempeño de rutinas no paramétricas y  autorregresivas","resumen":"falta","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240607,"idioma_id":5,"titulo":"RUPTURA DE LA DORMICIÓN Y EXIGENCIAS DE LUZ PARA LA GERMINACIÒN DE SEMILLAS DE Juglans nigra","resumen":"Se evaluaron métodos para superar la dormición y determinar las necesidades de luz en la germinación de Juglans nigra. Para superar la latencia y dureza del endocarpio se realizó Estratificación en caliente (T1), Inmersión en ácido giberélico (T2) y Estratificación en frío-húmedo (T3). Para la necesidad de luz se evaluó alternancia de oscuridad\/luz y oscuridad permanente. Se analizó el Porcentaje Germinación (% de G), Índice Velocidad de Germinación (IVG), Tiempo Medio Germinación Máxima (TMG), % Plántulas Normales, % Semillas sin germinar, Peso Seco Medio de plántulas (PSM) y el Índice de Germinación Relativo a la luz (GRL). En T1 no hubo germinación y en T2 irrelevante. T3 produjo diferencias altamente significativas en todas las variables analizadas, siendo el período de 4 meses de estratificación el mejor para romper la dormición. Al no ser la luz un factor determinante en la germinación, esta especie se clasificaría como fotoblástica neutra.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240608,"idioma_id":5,"titulo":"La Alumbrera y Campo Cortaderas: contribuciones desde las técnicas líticas a la complejidad social, política y económica tardía en Antofagasta de la Sierra","resumen":"En este trabajo avanzamos en la comparación de las técnicas líticas practicadas por los habitantes de La Alumbrera y Campo Cortaderas, dos sitios correspondientes a momentos tardíos emplazados en la microrregión de Antofagasta de la Sierra (Catamarca, Puna meridional argentina). El objetivo principal es continuar aportando a la comprensión de la vinculación señalada entre ellos y sus funcionalidades diferenciales en el escenario de creciente centralización social, política y económica propuesto entre las sociedades antofagasteñas luego de ca. 700 años AP. En este, La Alumbrera habría constituido un centro habitacional políticamente relevante y nodo\/centro de intercambio y caravaneo, al que estuvieron estrechamente vinculados otros asentamientos de la microrregión, uno de ellos Campo Cortaderas, sitio que habría funcionado como espacio especializado en actividades agrícolas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240609,"idioma_id":4,"titulo":"Cathodes of spent Li-ion batteries: Dissolution with phosphoric acid and recovery of lithium and cobalt from leach liquors","resumen":"This paper presents the study of an innovative process: the reductive dissolution of mixed lithium cobalt oxide contained in the cathodes of spent Li-ion batteries with phosphoric acid. The studied parameters were: reaction time, temperature, stirring speed, solid-liquid ratio and concentrations of the leaching agent (H3PO4) and the reducing agent (H2O2). Reactants and productswere characterized by atomic absorption spectroscopy (AAS), X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). The results showed that the reducing dissolution process with phosphoric acid is an efficient way for the extraction of lithium and cobalt, achieving dissolution values close to 100%. In addition, a recovery of 88% of Li+as Li3PO4 and 99% of Co+2 as CoC2O4, with purities of 98.3% and 97.8% was found respectively.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240611,"idioma_id":4,"titulo":"Synthesis of Lithium Fluoride from Spent Lithium Ion Batteries","resumen":"Lithium (Li) is considered a strategic element whose use has significantly expanded. Its current high demand is due to its use in lithium ion batteries for portable electronic devices, whose manufacture and market are extensively growing every day. These days there is a great concern about the final disposal of these batteries. Therefore, the possibility of developing new methodologies to recycle their components is of great importance, both commercially and environmentally. This paper presents results regarding important operational variables for the dissolution of the lithium and cobalt mixed-oxide (LiCoO2) cathodes from spent lithium ion batteries (LIBs) with hydrofluoric acid. The recovery and synthesis of Co and Li compounds were also investigated. The dissolution parameters studied were: temperature, reaction time, solid-liquid ratio, stirring speed, and concentration of HF. The investigated recovery parameters included: pH, temperature, and time with and without stirring. The final precipitation of lithium fluoride was also examined. The results indicate that an increase in the HF concentration, temperature, and reaction time favors the leaching reaction of the LiCoO2. Dissolutions were close to 60%, at 75 C and 120 min with a HF concentration of 25% (v\/v). The recovery of Co and Li were 98% and 80%, respectively, with purities higher than 94%. Co and Li compounds, such as Co3O4 and LiF, were synthesized. Furthermore, it was possible to almost completely eliminate the F- ions as CaF2.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240612,"idioma_id":4,"titulo":"Hydrometallurgical extraction of Al and Si from kaolinitic clays","resumen":"Herein is presented the results of a study on the hydrometallurgic extraction and recovery of aluminum and silicon by leaching of kaolinitic clays with HF. The studied extraction parameters were: temperature, reaction time, solid\/liquid ratio, concentration, and precipitating agent mass. In the leaching process, mineral dissolutions near 100% were obtained when working at 348 K, solid\/liquid ratio2% w\/v, HF 12% v\/v, for 120 minutes. The HF leach liquor generated from thedissolution of kaolinitic clays contains H2SiF6 and H3AlF6. Studies were conducted to recover the two valuable fluorides as K2SiF6 and Na3AlF6 by precipitation with alkaline salts from the leach liquor. Phases of precipitated fluorides were identified by XRD and surface morphology by SEM. The purity of the K2SiF6 precipitate was 98.8%, whereas for Na3AlF6, it was 89.3%. Also, both synthesized solids are of high commercial value due to their industrial applications.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240613,"idioma_id":4,"titulo":"Recovery Process of Li, Al and Si from Lepidolite by Leaching with HF","resumen":"This work describes the development of a new process for the recovery of Li, Al and Sialong with the proposal of a flow sheet for the precipitation of those metals. The developed process is comprised of lepidolite acid digestion with hydrofluoric acid, and the subsequent precipitation of the metals present in the leach liquor. The leaching operational parameters studied were: reaction time, temperature and HF concentration. The experimental results indicate that the optimal conditions to achieve a Li extraction higher than 90% were: solid-liquid ratio, 1.82% (w\/v); temperature, 123 °C; HF concentration, 7% (v\/v); stirring speed, 330 rpm; and reaction time, 120 min. Al and Si can be recovered as Na3AlF6 and K2SiF6. LiF was separated from the leach liquor during water evaporation, with recovery values of 92%.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240618,"idioma_id":5,"titulo":"Avance de investigación Grupo de investigación en Comunicación GIC: 'Producción de tesinas y géneros académicos'","resumen":"2017: Avance de investigación Grupo de investigación en Comunicación GIC: 'Producción de tesinas y géneros académicos', Ciencias Sociales, Revista de la Facultad de Ciencias Sociales Nº 94, agosto de 2017, 146-148. ISSN 1666-7301. Disponible en: http:\/\/www.sociales.uba.ar\/wp-content\/blogs.dir\/219\/files\/2017\/09\/94_-avances_web.pdf","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240622,"idioma_id":5,"titulo":"Algas verdes y euglénidos de la puna argentina.","resumen":"El objetivo de este trabajo fue contribuir al conocimiento cualitativo de las clorofitas y euglenofitas de la puna argentina. Estos ambientes se caracterizan por ser sistemas extremos, dinámicos y frágiles, esenciales para el funcionamiento de pequeñas cuencas hidrográficas altoandinas. Durante el verano de 2005 se efectuó un muestreo que abarcó veintiséis cuerpos lénticos en las provincias de Jujuy, Salta y Catamarca. Las muestras se obtuvieron por el concentrado de 25 litros de agua a través de una red de plancton de 20 µm de poro y fueron fijadas ?in situ? con formaldehído 4%. Las determinaciones algales se realizaron en laboratorio bajo microscopio binocular con dispositivo para dibujo. Se reconocieron 28 taxones que pertenecieron 24 a Chlorophyta  y 4 a Euglenophyta. El número más alto de especies fue ocho en Los Enamorados (Jujuy) y sin registro en el 26% de los cuerpos de agua muestreados. De acuerdo a los resultados, hubo un predominio de especies raras, la mayoría cosmopolitas y de medios salinos. De ahí que diecisiete de las veintiocho entidades determinadas, es decir el 60,7%, fueron encontradas en ambientes salinos. Chlamydomonas rubrifilum, Oedogonium sp. 1 y Stigeoclonium sp. 2 fueron halladas sólo en aguas hipersalinas, Chlamydomonas tremulans, Oedogonium sp. 3, Spirogyra sp. 1, Spirogyra sp. 2, Ulothrix pseudoflacca var. salina, Euglena ehrenbergii y Euglena proxima también estuvieron a salinidades menores. En el caso de Raciborskiella salina fue detectada en aguas tanto salinas como salinas-hipersalinas con conductividades de hasta 22500 µS\/cm. Los taxones de algas verdes y euglénidos enunciados en esta publicación son nuevas citas para estos humedales debido a que no se contaba con antecedentes previos para estos grupos. Por otro lado, Ulothrix pseudoflacca var. salina es mencionada por primera vez para el Noroeste Argentino (NOA).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240623,"idioma_id":5,"titulo":"Catálogo de la Colección Ficológica de la Fundación Miguel Lillo. Parte II: Material de la Kryptogamae exsiccatae.","resumen":"Este trabajo constituye la segunda entrega del Catálogo de la Colección Ficológica de la Fundación Miguel Lillo e incluye el listado del material algal proveniente de la Kryptogamae exsiccatae editada por el Museo de Historia Natural de Viena que se encuentra resguardado en la Colección Ficológica. Las 489 muestras algales catalogadas representan 198 géneros distribuidos en las divisiones Cyanophyta (131 ejemplares), Chlorophyta (111), Charophyta (87), Rhodophyta (82), Ochrophyta (77) y Dinophyta (1). Los colectores más representados en el material revisado son S. Stockmayer (58 ejemplares), F. Filárszky (39), E. C. Teodorescu (36), C. Rechinger (36) y K. von Keissler (28). El material depositado representa principalmente la Flora Algal Europea de fines del siglo XIX y principios del XX.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240624,"idioma_id":5,"titulo":"Nuevos registros de Bacillariophyceae en ecosistemas lóticos del Noroeste de Argentina I","resumen":"Resumen: Taboada, María de los Á.; Silvia N. Martínez De Marco; Beatriz Tracanna; M. Soledad Bustos. 2017. ?Nuevos registros de Bacillariophyceae en sistemas lóticos del Noroeste de Argentina I?. Lilloa 54 (2). Las condiciones orográficas y climáticas del Noroeste Argentino permiten la existencia de numerosos ecosistemas lóticos que albergan una gran diversidad en su biota. Los arroyos Calimayo y Mista forman parte de la cuenca del río Salí. En estos sistemas las diatomeas (Bacillariophyceae) constituyen un grupo taxonómico muy amplio y con una elevada riqueza específica. El objetivo propuesto en este trabajo fue dar a conocer 25 nuevos registros de diatomeas, de los cuales 5 se registran por primera vez para Tucumán, 7 son citados para el NOA y 13 para el país. Se realizaron muestreos estacionales en ambos arroyos desde 2012 a 2014, se recolectaron datos bióticos (epiliton y fitoplancton) y se midieron factores abióticos in situ, según metodologías convencionales. Se detallan características morfométricas, distribución geográfica y rasgos autoecológicos de los taxones registrados por primera vez para el NOA y el país. Se incorporan microfotografías (MO) de las especies citadas. La investigación y los relevamientos diatomológicos realizados a nivel regional permitieron ampliar el conocimiento, la distribución y la autoecología de las especies algales estudiadas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240625,"idioma_id":5,"titulo":"Evaluación del fitoplancton y calidad del agua de un arroyo subtropical del Noroeste Argentino.","resumen":"El arroyo Calimayo forma parte de la cuenca del río Salí, principal red fluvial de la región. Este sistema lótico fue conocido por su gran diversidad biológica. Debido a la instalación de una papelera y por sus efluentes las condiciones ecológicas se modificaron. El objetivo fue analizar el fitoplancton y la calidad del agua del arroyo Calimayo. Se realizaron muestreos estacionales desde invierno\/2012 a otoño\/2013 en tres sitios (S1: tramo alto, S2 y S3: sectores medio y bajo, respectivamente). Se recolectaron muestras ambientales y biológicas según metodología convencional. Los mayores registros de temperatura, pH y conductividad eléctrica se presentaron en S2 y S3. El S1 tuvo los máximos valores de oxígeno disuelto y la menor demanda bioquímica de oxígeno. Las diatomeas sobresalieron tanto cuali como cuantitativamente del resto de los grupos algales. El RDA permitió diferenciar dos grupos fitoplanctónicos en relación a variables abióticas. El S1 estuvo influenciado por estacionalidad, litología y fisicoquímica del agua, denotando un buen estado ecológico. En S2-S3 las condiciones ecológicas se vieron afectadas por el estado trófico del agua y los efluentes polutos, por lo que la calidad y el fitoplancton se vieron notoriamente deteriorados. La ficoflora resultó ser un buen indicador de este sistema lótico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240629,"idioma_id":5,"titulo":"Abstracción y matemática en el Comentario a la Física de Tomás de Aquino: más allá de las operaciones intelectuales","resumen":"Durante buena parte del siglo XX, uno de los grandes debates en el ámbito de los estudios sobre la doctrina del conocimiento según Tomás de Aquino fue aquél que rodeó la cuestión del proceso abstractivo. Particularmente la atención se volcó sobre el rol de este último como causa de la determinación de los objetos de ciencia especulativa. Dejando de lado las particularidades (y disparidades) de esta discusión, el presente trabajo pretende enfocarse en el análisis particular de un texto en el cual la abstracción ?aun figurando como el fundamento de la distinción de los objetos que estudia la matemática? no parece designar un tipo de operación intelectual. Por el contrario, la abstracción figura como una propiedad de las propias esencias o formas matemáticas. En lo sucesivo se esbozará una interpretación de dicho texto y se enumerarán algunas objeciones contra dicha interpretación a las cuales se intentará dar respuesta. Las consecuencias de este hallazgo podrían conllevar la revisión de algunas ideas que se han vuelto comunes en la epistemología tomista. La revista se encuentra indizada en SCOPUS, SciELO Citation Index - Thomson Reuters, SCIELO, DOAJ, REDALyC, The Philosopher´s Index, Index Copernicus, Gale Cengage Learning, Ulrichs Web, entre otros.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240632,"idioma_id":5,"titulo":"Tomás de Vio Cayetano, o la modernidad en letras medievales","resumen":"El presente trabajo se propone sintetizar y valorar críticamente los puntos más salientes del recientemente publicado libro Objetividad y ciencia en Cayetano. Una prefiguración de la Modernidad. Como podrá verse, se trata de una obra de gran relevancia para el campo ya que analiza y demuestra el carácter disruptivo que presentan algunas tesis de Tomás de Vio con respecto al pensamiento de Tomás de Aquino, a quien pretende estar comentando. Estos descubrimientos implican importantes consecuencias para el modo de comprender el devenir de la escuela tomística fundada en torno a su legado. La revista se encuentra indizada en Arts & Humanities Citation Index (A&HCI) SCOPUS, FRANCIS, ERIH PLUS, DOAJ (Directory of Access Journal), Philosopher?s Index, REDIB. Red Iberoamerica de Innovación y Conocimiento Científico, SCIMAGO JOURNAL RANK","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240636,"idioma_id":4,"titulo":"A note on the use of the Companion Solution (Dirichlet Green's function) on meshless boundary element methods","resumen":"Most implementations of meshless BEMs use a circular integration contours (spherical in 3D) embedded into a local interpolation stencil with the so-called Companion Solution (CS) as a kernel, in order to eliminate the contribution of the single layer potential. However, the Dirichlet Green´s Function (DGF) is the unique Fundamental Solution that is identically zero at any given close surface and therefore eliminates the single layer potential. One of the main objectives of this work is to show that the CS is nothing else than the DGF for a circle collocated at its origin. The use of the DGF allows the collocation at more than one point, permitting the implementation of a P-adaptive scheme in order to improve the accuracy of the solution without increasing the number of subregions. In our numerical simulations, the boundary conditions are imposed at the interpolation stencils in contact with the problem boundary instead of at the corresponding integration surfaces, permitting always the use of circular integration contours, even in regions near or in contact with the problem domain where the densities of the integrals are reconstructed from the interpolation formulae that already included the problem boundary conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240637,"idioma_id":4,"titulo":"Assessment of the SWAT model to simulate a poorly gauged watershed of the Pampas region","resumen":"Argentina has been among the world leaders in the production and exportof agricultural products since the nineties. The Carcara~n´a River lower basin(CRLB), a rainfed cropland of the Pampas region, is located in a poorly gaugedarea which has limited hydrological data and water resources assessment. Thiswork explores the application of Soil and Water Assessment Tool (SWAT) modelto the CRLB in Santa Fe province. The analysis of field collected and remotesensing data characterizing hydrology, water quality, soil types, land use\/landcover, management practices and crop yield, guarantee a SWAT modeling holistic approach. A combined manual and automated calibration and validationprocess incorporating sensitivity and uncertainty analysis is carried out usinginformation about internal watershed behaviour. Eleven N-P fertilizer rates areselected to simulate the impact of N fertilizer on crop yield, plant uptake, aswell as runoff and leaching losses. Different indices are considered to assessnitrogen use efficiency. The overall quality of the fit is satisfactory consideringthe input data limitations. This work provides, for the first time in Argentina,a reliable technological tool to simulate yield response to soil quality and water availability capable to meet defined environmental targets that would be readyto support decision making on planning public policies and private activities onthe Pampas region. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240639,"idioma_id":4,"titulo":"Hybridizing Feature Selection and Feature Learning Approaches in QSAR Modeling for Drug Discovery","resumen":"Quantitative structure-activity relationship modeling using machine learning techniques constitutes a complex computational problem, where the identification of the most informative molecular descriptors for predicting a specific target property plays a critical role. Two main general approaches can be used for this modeling procedure: feature selection and feature learning. In this paper, a performance comparative study of two state-of-art methods related to these two approaches is carried out. In particular, regression and classification models for three different issues are inferred using both methods under different experimental scenarios: two drug-like properties, such as blood-brain-barrier and human intestinal absorption, and enantiomeric excess, as a measurement of purity used for chiral substances. Beyond the contrastive analysis of feature selection and feature learning methods as competitive approaches, the hybridization of these strategies is also evaluated based on previous results obtained in material sciences. From the experimental results, it can be concluded that there is not a clear winner between both approaches because the performance depends on the characteristics of the compound databases used for modeling. Nevertheless, in several cases, it was observed that the accuracy of the models can be improved by combining both approaches when the molecular descriptor sets provided by feature selection and feature learning contain complementary information.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240640,"idioma_id":4,"titulo":"GeRNet: A Gene Regulatory Network Tool","resumen":"Gene regulatory networks (GRNs) are crucial in every process of life since they govern the majority of the molecular processes. Therefore, the task of assembling these networks is highly important. In particular, the so called model-free approaches have an advantage modeling the complexities of dynamic molecular networks, since most of the gene networks are hard to be mapped with accuracy by any other mathematical model. A highly abstract model-free approach, called rule-based approach, offers several advantages performing data-driven analysis; such as the requirement of the least amount of data. They also have an important ability to perform inferences: its simplicity allows the inference of large size models with a higher speed of analysis. However, regarding these techniques, the reconstruction of the relational structure of the network is partial, hence incomplete, for an effective biological analysis. This situation motivated us to explore the possibility of hybridizing with other approaches, such as biclustering techniques. This led to incorporate a biclustering tool that finds new relations between the nodes of the GRN. In this work we present a new software, called GeRNeT that integrates the algorithms of GRNCOP2 and BiHEA along a set of tools for interactive visualization, statistical analysis and ontological enrichment of the resulting GRNs. In this regard, results associated with Alzheimer disease datasets are presented that show the usefulness of integrating both bioinformatics tools.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240641,"idioma_id":5,"titulo":"Infancias Deficientes y Anormales: Iniciativas Psiquiátrico-Pedagógicas entre la Academia, la Beneficencia y el Estado en Rosario, Argentina (1920-1940)","resumen":"El artículo indaga las iniciativas médico-pedagógicas promovidas por el psiquiatra italiano Lanfranco Ciampi para el tratamiento de los niños deficientes en la ciudad de Rosario, Argentina, durante el período de entreguerras. Pretende analizar la circulación de la propuesta de Sante de Sanctis, y la deriva social y material de estas ideas sobre la anormalidad infantil en esta ciudad, a partir de la constitución de un dispositivo de atención, enseñanza y clínica al crearse la Universidad Nacional del Litoral. A través de un análisis cualitativo de fuentes institucionales, el trabajo intentará mostrar la imbricación entre saberes y práctica, en especial considerando -más allá de las producciones teóricas- las instituciones y los actores involucrados que permitieron llevarlas a cabo. Concluimos observando la incorporación de la educación especial y la ortofonía a la esfera educativa del Estado provincial a principios de los años cuarenta.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240642,"idioma_id":5,"titulo":"La creación clínica de normas sexuales Nosología, patologización y contramodelos sexuales en la Penitenciaría Nacional de Buenos Aires (Argentina, 1901-1904)","resumen":"El siguiente artículo se ocupa del problema de la construcción de nosologías médico- psiquiátricas referidas a la sexualidad, tomando para ello los casos de inversión sexual (travestismo) analizados por Francisco de Veyga en el Servicio de Observaciones de Presuntos Alienados de la Penitenciaría Nacional, en Argentina, a principios del siglo XX. El interés reside en la operatoria por la cual el alienista construye categorías nosográficas ex nihilo, para dar cuenta de las formas de vida y subjetivación que ciertos sujetos desarrollaban y que amenazaban el canon de la normalidad. A su vez, en la voz de De Veyga se traslucen algunos aspectos sobre la moralidad en la vida porteña, que contrastaba con la escena de peligro que éste buscaba plantear. Con ello, interesa analizar un caso específico, donde el alienismo local comienza a intervenir y teorizar, sobre cuerpos y subjetividades disidentes, a partir de la construcción de un discurso grotesco, para calificar formas de vida en los márgenes de la normalidad que buscaba establecerse, propio de los efectos de poder normalizadores que Foucault reconociera en las pericias médico legales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240645,"idioma_id":5,"titulo":"Programa de fortalecimiento parental en contextos de vulnerabilidad social: Una propuesta desde el ámbito escolar","resumen":"El trabajo que se informa destaca el rol relevantede la familia y del ejercicio adecuado de laparentalidad para el desarrollo humano. Dadoque las competencias parentales estarían relacionadascon el contexto social, se describen las característicasde las familias en vulnerabilidad social,teniendo en cuenta los riesgos psicosocialesa los que muchas veces están expuestas, las consideracionesculturales de lo que significa ser bue -nos padres y las propias experiencias de los progenitoreso cuidadores en sus familias de origen.Se revisan diversas modalida des de programas deintervención familiar y parental, destacando laim portancia del diseño, imple mentación y evaluaciónde estos programas en contextos de vulnerabilidadsocial. En es te marco, y considerandoque en Argentina exis te un escaso desarrollo deprogramas de apoyo a las familias so cialmentevul nerables, se presenta una propues ta de intervenciónaplicable en el ámbito escolar y dirigidaa fortalecer las competencias parentales.El programa propuesto, basado en el enfoquede la parentalidad positiva, integra elementosde los modelos de intervención educativo y comunitario,ya que se implementa en forma grupal,mediante encuentros expositivo-participativosy en coordinación con la escuela a la queasisten los hijos de los beneficiarios. Como conclusióny en función de la experiencia obtenidapor las interventoras y la observada en las madresparticipantes, se presenta una reflexión sobre lascontribuciones de la intervención propuesta ylos de safíos pendientes para futuras aplicacionesdel programa.Palabras clave: Parentalidad; Educación parental;Intervención; Relación familia - escuela; Vulnerabilidadsocial.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240646,"idioma_id":5,"titulo":"Laboratorio portátil de escritorio para la enseñanza de la electrónica","resumen":"La forma de impartir enseñanza debe cambiar para satisfacer a la nueva generación de estudiantes que quiere aprender por vías no tradicionales y empleando nuevas tecnologías. Los estudiantes de esta generación se consideran dueños de las Tecnologías deInformación y Comunicación (TICs), poseen una asombrosa capacidad de adaptación en toda actividad que las implique, y ostentan un nivel de decodificación visual o iconográfica mayor que las generaciones anteriores, por lo que a veces rechazan los modos tradicionales de exposición En este trabajo se presentauna propuesta de estrategia metodológica basada en el aprendizaje experiencial de Kolb para ser aplicado a la enseñanza de la Electrónica Básica mediante la implementación de laboratorios portátiles de escritorio en diferentes asignaturas de la carrera Ingeniería en Electrónica (UNCa).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240647,"idioma_id":4,"titulo":"INFLUENCE OF HEAT STRESS ON WHITE BLOOD CELL TOTAL COUNT AND NEUTROPHIL\/LYMPHOCYTE RATE IN HOLANDO ARGENTINO DAIRY COWS","resumen":"No disponible - enviado para su publicación","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240648,"idioma_id":5,"titulo":"INFLUENCIA DEL ESTRÉS CALÓRICO SOBRE LOS GLÓBULOS BLANCOS EN VACAS HOLANDO ARGENTINO","resumen":"La combinación de altas temperaturas y humedad, características de la provincia de Santa Fe, principal zona de producción lechera de Argentina, afectan la producción láctea. El índice de temperatura y humedad (ITH) puede ser utilizado como un indicador de estrés térmico. El objetivo de esta investigación fue evaluar los efectos del estrés calórico sobre los glóbulos blancos en respuesta a la liberación de cortisol en bovinos productores de leche. El estudio se realizó en el Módulo Tambo de la Facultad de Ciencias Agrarias, situado en Zavalla (33°1´S, 60°53´O), Santa Fe, Argentina, durante el período 2013-2014. Se utilizaron 30 vacas Holando Argentino, del rodeo de vacas en ordeñe de segunda y tercera lactancia. Las muestras fueron tomadas en primavera (ausencia de olas de calor) y verano (presencia de olas de calor), durante el ordeño de la mañana y de la tarde. Se utilizó un método de radioinmunoanálisis para dosar cortisol, (Kit comercial Coat-A-Count Cortisol); un contador hematológico, MINDRAY-BC 2800, para determinar la cantidad total de glóbulos blancos, y la coloración de May Grünwald y Giemsa para determinar la cantidad de neutrófilos y linfocitos. Se observó aumento del ITH en las tardes de verano, coincidiendo con un aumento significativo de cortisol, una disminución relativa del número de linfocitos y un aumento del número de neutrófilos. La relación Neutrófilos\/Linfocitos también fue mayor en verano. Se concluye que el estrés calórico, medido a través del ITH, modifica el número y la proporción de glóbulos blancos, y esto podría atribuirse al aumento del cortisol plasmático.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240649,"idioma_id":4,"titulo":"Evaluation of Stress Response and Apoptosis on Leucocytes in TIVA versus Balanced Anesthesia","resumen":"Background: The aim of this study was to assess the stress response andapoptosis on leucocytes, in patients under two different anesthetics techniques.Methods: Thirty patients ASA I-II were prospectively randomizedinto two groups to receive either total intravenous anesthesia with propofolremifentanil(TIVA Group , n = 15) or balanced inhalation anesthesia withsevoflurane-remifentanil (BAL Group, n = 15). The hemodynamic response:systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate(HR) at different time points: baseline, after intubation, after skin incision andat the end of surgery, was measured along with plasma levels of lactate, glucose,cortisol and leucocytes count. The biomarkers of apoptosis (Annexin Vand Propidium Iodide) in neutrophils, monocytes and lymphocytes were evaluatedat baseline, intraoperatively and two hours after surgery. Results: Thestudy groups were comparable with respect to anthropometric data. No significantintergroup differences in SBP and DBP were revealed. The HR in theBAL group was lower after intubation (p = 0.007). In both groups, lactate,plasma glucose, cortisol and leucocytes count remained stable during surgeryand two hours post-operatively. In the BAL group there were significant differencesin Annexin V in neutrophils, baseline moment (p = 0.010). No significantdifferences were found in apoptosis markers (Annexin V and PropidiumIodide) in neutrophils, monocytes and lymphocytes, at different timepoints. Conclusion: Both TIVA and BAL were effective in suppressing thesurgical stress, without inducing apoptosis in immune cells, in patients undergoingVCL.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240652,"idioma_id":5,"titulo":"Reportes Integrados. Situacion actual en latinoamerica y analisis de su estructura","resumen":"Con fecha 9\/12\/2013, el Consejo Internacional de Información Integrada publicó el Marco Conceptual para laelaboración de los Informes Integrados. Con el blanco en brindar información sobre las fuentes de creación de valoren las empresas, el Consejo considera que los mismos promueven un enfoque más eficiente de presentación dereportes corporativos y tienen por objetivo mejorar la información para la toma de decisiones de los proveedores decapital como camino para optimizar la asignación de recursos. Las autoras abordan la situación actual en la región yel análisis de su estructura, habiéndose desarrollado tal Marco haciendo foco en el sector privado lucrativo, aunque sereconoce que su aplicabilidad es compatible para el sector público y el sector privado sin fines de lucro.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240653,"idioma_id":4,"titulo":"Manipulation of a Senescence-Associated Gene Improves Fleshy Fruit Yield","resumen":"-","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240654,"idioma_id":4,"titulo":"Phytochromobilin deficiency impairs sugar metabolism through the regulation of cytokinin and auxin signaling in tomato fruits","resumen":"-","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240655,"idioma_id":5,"titulo":"Problemas y desafíos de la traducción de las lenguas indígenas. Los casos toba y maká de la región del Gran Chaco (Argentina y Paraguay)","resumen":"Este trabajo trata sobre los problemas de la traducción entendida como una actividad translingüística e intercultural que involucra tomar decisiones no solo en el nivel lingüístico (estructural) sino también en el comunicativo y performativo del lenguaje. Con el propósito de abarcar estos dos niveles, seleccionamos, por un lado, dos categorías gramaticales de las lenguas toba y maká: los marcadores de posesión alienable y la evidencialidad. Dado que se trata de categorías no referenciales y pragmáticas, sus significados culturales podrían perderse en el proceso de traducción. Por otro lado, seleccionamos dos rasgos del arte verbal toba y maká que evidencian que el discurso oral indígena posee su propia estructura y organización, aun cuando pueda parecer errático o azaroso. Estos rasgos son la estructura prosódica del consejo toba y la repetición de los conectores discursivos en la narrativa toba y maká. Así también, el interés teórico de este trabajo es reflexionar sobre el modelo de lengua que subyace tanto a la descripción lingüística como a la traducción. Nuestro análisis está basado en un corpus de datos de primera mano recogidos durante sucesivos trabajos de campo en comunidades tobas y makás de la región del Gran Chaco.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240656,"idioma_id":5,"titulo":"Lenguas indígenas en la escuela: una mirada retrospectiva a la educación intercultural bilíngüe en la provincia de Chaco (Argentina)","resumen":"El artículo revisa las políticas de Educación Intercultural Bilingüe en el Chaco (Argentina) entre 1987 y 2016. Se analizan dos momentos vinculados con el marco legal y el tratamiento de las lenguas 1 CONICET y Universidad de Buenos AiresHECHT, Ana Carolina; MESSINEO, Cristina. .  \/ Revista do Programa de Pós-Graduação em Linguística da Universidade Federal do Rio deJaneiro. Volume 13, n.1 jan de 2017, p. 245-261. ISSN  1. [https:\/\/revistas.ufrj.br\/index.php\/rl]246 Volume 13, n1 - Janeiro 2017Educação e Revitalização Linguísticasindígenas en la escuela. Primero, la visibilización de la diversidad etnolingüística, las demandas dealfabetización bilingüe y el rol del maestro indígena. Segundo, el plurilingüismo, la interculturalidady el acceso de los indígenas a los niveles educativos superiores se tornan cuestiones relevantes. Elproceso va acompañado de un giro en la situación sociolingüística de los pueblos indígenas quereclaman una escuela involucrada en la revitalización de sus lenguas","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240659,"idioma_id":5,"titulo":"Valoración de la atención primaria de la salud en el Centro de Medicina Familiar y Comunitaria San Pantaleón desde la perspectiva de los profesionales de la salud (estudio de corte transversal)","resumen":"RESUMENLa atención primaria de la salud (APS) favorece un cuidado más eficiente y equitativo en relación con las necesidades de la población. El objetivode este estudio de corte transversal realizado durante 2013 fue evaluar el grado de implementación de las funciones fundamentales de la APS enel Centro de Salud de Medicina Familiar y Comunitaria San Pantaleón (CMFyCSP), ubicado en Boulogne, partido de San Isidro, Buenos Aires,República Argentina, desde la perspectiva de los profesionales de la salud. Se administró en forma electrónica la Herramienta de Evaluación de laAtención Primaria (en inglés Primary Care Assessment Tools: PCAT) para profesionales de salud validada en la Argentina. Todos los profesionalescon una antigüedad de dos años o mayor (n=25) la contestaron en forma completa. La puntuación global de las funciones esenciales de APSfue 16,75 (DE 1,42) para un máximo de 24 puntos. Enfoque Familiar, Integralidad\/Servicios Prestados y Coordinación\/Sistemas de Informaciónfueron las funciones con mejor puntaje (3,51 [DE 0,55], 3,49 [0,58] y 3,16 [0,47], respectivamente.Palabras clave: Atención Primaria de Salud, medicina comunitaria, estudios transversales.ASSESSMENT OF PRIMARY HEALTH CARE?S FUNCTIONS IN A HEALTH CENTER OF BUENOS AIRES FROMTHE PERSPECTIVE OF HEALTH PROFESSIONALS: CROSS-SECTIONAL STUDYABSTRACTPrimary health care (PHC) favors more efficient and equitable attention to the needs of the population. The objective of this cross-sectional studycarried out during 2013 was to evaluate the degree of implementation of the basic functions of PHC in the San Pantaleón Family and CommunityMedicine Health Center (CMFyCSP), located in Boulogne, San Isidro, Buenos Aires, Argentina, from the perspective of health professionals. ThePrimary Care Assessment Tool (PCAT) for health professionals validated in Argentina was administered electronically. All professionals with aseniority of at least two years (n = 25) responded the survey. The overall score for essential APS functions was 16.75 SD (1.42) for a maximumof 24 points. Family Focus, Integrality \/ Rendered Services and Coordination \/ Information Systems were the functions with the highest scores(3.51 [0.55], 3.49 [0.58], and 3.16 [0.47], respectively.Key words: Primary Health Care, Community Medicine, Cross-Sectional StudiesRev. Hosp. Ital. B.Aires 2017; 37(1): 4-9.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240660,"idioma_id":4,"titulo":"Medication discrepancies and potentially inadequate prescriptions in elderly adults with polypharmacy in ambulatory care","resumen":"Objectives: The objective of this study is to describe the frequency and type of medication discrepancies (MD) through medicationreconciliation and to describe the frequency of potentially inadequate prescription (PIP) medications using screening tool ofolder persons? prescriptions criteria. Design: Cross-sectional comparison of electronic medical record (EMR) medication lists andpatient?s self-report of their comprehensive medication histories obtained through telephone interviews. Inclusion criteria: Elderlyindividuals (>65 years old) with more than ten medications recorded in their EMR, who had not been hospitalized in the pastyear and were not under domiciliary care, affiliated to a private community hospital. Outcome Measures: The primary outcomeswere the proportion of patients with MD and PIP. Secondary outcomes were the proportion of types of discrepancies and PIP. Weanalyzed possible associations between these variables and other demographic and clinical variables. Results: Out of 214 randomlyselected individuals, 150 accepted to participate (70%). The mean number of medications referred to be consumed by patients was9.1 (95% confidence interval [CI] =8.6?9.6), and the mean number of prescribed medications in their EMR was 13.9 (95% CI = 13.3?14.5).Ninety-nine percent had at least one discrepancy (total 1252 discrepancies); 46% consumed at least one prescription not documentedin their EMR and 93% did not consume at least one of the prescriptions documented in their EMR. In 77% of the patients, a PIPwas detected (total 186), 87% of them were at least within one of the following categories: Prolonged used of benzodiazepines orproton pump inhibitors and the use of aspirin for the primary prevention of cardiovascular disease. Conclusions: There was a highprevalence of MD and PIP within the community of elderly adults affiliated to a Private University Hospital. Future interventionsshould be aimed at reducing the number of PIP to prevent adverse drug events and improve EMR accuracy by lowering medicationsdiscrepancies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240661,"idioma_id":4,"titulo":"Chelate route for the synthesis of PbZrxTi1&minus;xO3 thin films","resumen":"Abstract: A chemical solution deposition route using the chelate approach was developed for the synthesis of PbZrxTi1&#8722;xO3 thin films. The route avoids the highly toxic 2-methoxyethanol used in previous formulations and offers the advantage of a simple and rapid solution synthesis without the need of distillation and refluxing strategies. The use of acetoin as chelating agent allows a transition between amorphous and final perovskite phases with no segregation of secondary phases during film growth. The obtained PbZrxTi1&#8722;xO3 films presented a thickness of &#8764;150 nm and exhibited good dielectric and ferroelectric properties. It was found that rapid thermal annealing facilitates the perovskite formation process and produces films with better ferroelectric properties than those sintered in conventional furnaces. Graphical Abstract: [InlineMediaObject not available: see fulltext.]","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240662,"idioma_id":4,"titulo":"Secondary Education in Argentina: A Winding Road","resumen":"This paper is aimed at exploring the state of the secondary education in Argentina, with special emphasis on thedifferent changes and approaches of inclusive education public policies introduced in the last years. Argentina hasbeen experiencing profound changes in relation to the population groups with access to the different educationallevels, presenting painful differences in the quality and effectiveness of education given in different population andgeographic sectors. Secondary education in Argentina is currently the educational level on which all eyes arefocused. On the one hand, due to the progressive obligatoriness, but to a greater extent a large number of secondaryschool age population are effectively excluded from the possibility of exercising the right to quality education. Thepaper tries to examine, through an analysis of the strengths, weaknesses, opportunities, and threats of theArgentinian educational system, what are the critical points of inflection where to incorporate elements ofinnovation to achieve better quality and inclusion standards in a country marked by deep levels of inequality in theaccess and quality of education in its different population groups. The research has been conducted through adescriptive methodology, using quantitative and qualitative analysis of primary and secondary sources. It is set on abibliographical review based on reports and studies of recent publications, coming from official, national,and international public institutions. The paper aims to be a first step in a diagnostic analysis of Argentinianeducation, but in a comparative manner, contrasting indicators and local indexes with international and regionaltrends in the subject. The main results point out that a deep transformation of the secondary school is needed, insuch a way as to respond to the many signs of inequality, fragmentation and poor quality of the most vulnerablepopulation groups","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240663,"idioma_id":4,"titulo":"A new approach to fishery waste revalorization to enhance Nile tilapia (Oreochromis niloticus) digestion process","resumen":"The main goal of this research is to analyze in vitro compatibility of Nile tilapia (Oreochromis niloticus) digestive proteinases and enzymes recovered from species comprising fishery waste as Pleoticus muelleri, Artemesia longinaris and Patagonotothen ramsayi. It evaluated the use of exogenous enzymes as feeds supplements to increase digestion efficiency in tilapia fingerlings and juveniles (3.5 ± 0.11 g and 11.6 ± 1.5 g, respectively). We successfully have obtained proteinases from fishery waste as source of exogenous enzymes. P. muelleri and A. longinaris enzymes had more activity of acid and alkaline proteinases than P. ramsayi. SDS-PAGE gels demonstrated that Nile tilapia digestive proteinases keep their activity when combined with each exogenous proteinase. Exogenous enzymes varied in their ability to enhance hydrolysis of different feed ingredients. P. muelleri by-products are the best candidates to be employed as feed supplements for tilapia juveniles. Enzymes from this by-product did not affect the activity and integrity of fish digestive enzymes, improved the hydrolysis of different protein sources (fish meal, squid meal, shrimp meal and soybean meal), and maintained its activity after being exposed to high temperatures and acid pHs. Our findings are applicable to other places where O. niloticus is raised utilizing local fishery waste, and also to different cultured species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240664,"idioma_id":5,"titulo":"EVALUACION A TRAVES DE LAS PERCEPCIONES DE LOS ALUMNOS DE POSGRADO DE FACULTAD DE CIENCIAS AGRARIAS-UNR SOBRE SU FORMACION","resumen":"Este trabajo aborda los procesos de formación de los estudiantes de posgrado de la Facultad de Ciencias Agrarias (UNR) donde se dictan seis carreras: un Doctorado, dos Maestrías y tres Especializaciones. El equipo, integrado por profesionales del área de gestión y de la cátedra de estadística, diseñó e implementó un instrumento encuesta para indagar sobre las dimensiones laboral, académica-científica, social y personal. El objetivo es conocer la valoración que efectúan los estudiantes de posgrado (PG) sobre su trayectoria formativa. Los aspectos relevados permitirán conocer el grado de satisfacción con el proceso de enseñanza aprendizaje, el grado de facilidad\/dificultad durante el cursado y la contribución para potenciar aspectos personales así como el impacto sobre la situación laboral. Entre otros resultados, surge que el 78% de los encuestados estuvo entre satisfecho y muy satisfecho con el estudio realizado; el 71% estimó como intermedia la facilidad para realizarlo relevándose que el tiempo fue la principal limitante, en particular, el tiempo para escribir (50%), para estudiar y realizar experimentos (36%) y para cursar (25%). El 90% expresó que el PG le posibilitó aumentar las capacidades personales. Sobre un 60% de encuestados en que se modificó la situación laboral, el 46% mejoró; el 70% lo atribuyó al PG.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240665,"idioma_id":4,"titulo":"Hemorheological action of trigonelline on in vitro glycated red blood cells","resumen":"Trigonelline (T) is an alkaloid found in seeds and leaves of different plant species. Recent studies have demonstrated its lipid lowering, antioxidant and anti-diabetic activity. The objective of this work was to evaluate the hemorheological action of trigonelline on glycated red blood cells (gRBC). Erythrocytes were incubated with glucose solutions (GS) at different concentrations. They were then treated with a solution of trigonelline. These samples were observed under an inverted optical microscope. Stationary and dynamic viscoelastic parameters were measured using an Erythrocyte Rheometer. Amplitude (Amp100) and half aggregation time (t½) were obtained by an optical chip erythrocyte aggregometer. When gRBC were treated with trigonelline, the results of the stationary viscoelastic parameters showed an increase with different GS concentrations. When gRBCs were treated with trigonelline (T) a slight decrease in phase-shift (&#948;) was observed at 1 Hz and a significant increase was evident at 0.5 Hz. Aggregation kinetics graphs showed Amp100 increase and t½ decrease for gRBC 1 g\/dL, while the inverse result was obtained for gRBC 0.2 g\/dL. Our results are useful to understand the mechanisms by which trigonelline can be used to mitigate the effects produced in erythrocytes as a consequence of diabetes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240666,"idioma_id":5,"titulo":"La deconstrucción del concepto de clases. El posmarxismo y las identidades colectivas no clasistas","resumen":"La centralidad de los conceptos de clase y lucha de clases, que comienza con la tradición clásica marxista y prosigue con fuerza en la teoría del siglo XX, fue disminuyendo en las últimas dos décadas de ese siglo, incluso en las filas del ?pensamiento crítico?. Después de la llamada ?crisis del marxismo?, el reflujo de la izquierda se manifestó, a nivel de la teoría social, mediante un desplazamiento de sus conceptos fuertes -en particular, del análisis en términos de clases- y un reemplazo por ?nuevas? nociones. Partiendo de este contexto entonces, en este trabajo analizamos la propuesta conjunta que Laclau y Mouffe hacen en Hegemonía y estrategia socialista, pues constituye una de las primeras y más importantes aportaciones a la deconstrucción posmarxista. Examinamos críticamente sus tesis sobre el antagonismo, la nueva lógica de constitución de lo social, la pluralidad e indeterminación, la contingencia, sus reproches a la concepción marxista de la sociedad y, en particular, su esfuerzo por ?deconstruir la noción misma de clase social? y de ?intereses de clase?, ante el diagnóstico de la emergencia en el capitalismo maduro de ?identidades colectivas no clasistas?. También analizamos el correlato que este planteo tiene en términos de estrategia política.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240667,"idioma_id":4,"titulo":"Mineralocorticoid receptor activation following acute myocardial stretch","resumen":"Myocardial stretch induces a two-phase increase in developed force. The first phase occurs immediately, is due to an increase in myofilament Ca2+ responsiveness, and is the expression of the Frank-Starling mechanism. The second phase, gradually developed, results from an increase in intracellular Ca2+ concentration and is known as ?slow force response? (SFR) to stretch. Characterization of the subcellular basis of the increase in Ca2+ responsible for the SFR development was an important objective of our laboratory group during last two decades. We have compiled enough evidence to suggest that the SFR is the mechanical expression of an autocrine\/paracrine loop of intracellular signals leading to the reactive oxygen species (ROS)-mediated activation of redox-sensitive kinases that activate (phosphorylate) the cardiac Na+\/H+ exchanger (NHE1), increasing intracellular Na+, and consequently, Ca2+ concentration. Recently, we demonstrated that mineralocorticoid receptor (MR) activation after stretch is critical for the progression of this complex signaling pathway. Interestingly, clinical evidence assigns a detrimental role to MR activation in the pathophysiology of heart failure (HF), in which cardiac wall stretch is an important triggering factor. The aim of this mini-review is not only to share our own experience describing novel non-genomic effects of MR activation after acute myocardial stretch and the physiological consequences, but also to discuss other possible pathophysiological implications, as well as the potential clinical impact of this important discovery.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240669,"idioma_id":4,"titulo":"Aggregation behaviour and solubilization capability of mixed micellar systems formed by a gemini lipoamino acid and a non-ionic surfactant","resumen":"In this work we carried out the physicochemical characterization of mixtures of a non-ionic surfactant and a gemini lipoamino acid one. The mixed systems were studied by surface tension measurements, fluorescence quenching and SAXS determinations. Both surfactants formed mixed micelles in different relationships and the properties of the mixtures were more similar to those of their major component. SAXS analysis showed that the micelles were triaxial ellipsoids, type core shell. The mixtures exhibited non-ideal behaviour, as indicated by critical micelle concentrations (CMC) lower than those of the individual surfactants, and negative interaction parameters, &#946;.The mixed surfactant systems produced enhanced water solubilization of polycyclic aromatic hydrocarbons, viz, naphthalene, phenanthrene and pyrene, quantified in terms of the molar solubilization ratio and the micelle-water partition coefficient. Synergism due to the presence of both surfactants in the mixture was observed for the solubilization of naphthalene and phenanthrene, but not for pyrene. This difference in behaviour might be related to the CMC and structure of the surfactants, the polarity of the solutes, and their association constants with the micellar phase.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240670,"idioma_id":4,"titulo":"Air quality loss in urban centers of the Argentinean dry Chaco: wind and dust control  as two scientifically neglected ecosystem services","resumen":"Dry Chaco is one of the most active agriculture frontiers, which imposes trade-offs and synergies with ecosystem services (ES). Most studies analyze real or potential supply of ES associated to land use change; but they usually neglect ES social demands. Interviews of inhabitants of small urban centers in the Dry Chaco.revelaled that windbreak and dust protection are high valued ES in towns within agricultural context. The absence of such perception in forest-context urban centers, and the seasonal patterns of precipitation, wind speed and land cover validate the reality of such demand. Loss of air quality ?as an agricultural disservice- is a socially demanded ES so far ignored in the environmental research agenda, which should be reversed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240671,"idioma_id":4,"titulo":"Invasion of Ligustrum lucidum (Oleaceae) in subtropical secondary forests of NW Argentina: declining growth rates of abundant native tree species","resumen":"Aims. Ligustrum lucidum, native of China, is one of the dominant exotic and invasive tree species in secondary forests in Argentina. 1) We assessed its invasion during 20 years in post-agricultural secondary forests dominated by native tree species, and 2) evaluated tree demographic rates of native individuals under and away from L. lucidum trees that invaded these forests.Locations. Four 1-ha permanent plots of secondary forests in the subtropical Andes of Tucumán, Argentina.Methods. We quantified the invasion of L. lucidum individuals (&#8805; 10 cm diameter) from 1991 to 2011 within four 1-ha plots of secondary forests and analyzed annual growth and mortality rates of native tree individuals (&#8805; 10 cm diameter) under and away from L. lucidum trees. For this, we compared tree demographic rates of all native individuals together (community level) under and away from individuals of L. lucidum, referred to as exotic and native neighbourhoods, respectively. Then, we described the relative growth rate of native tree species in exotic \/ native neighbourhoods (species level) and related them with their demographic life histories and morpho- physiological traits.Results. Both density and basal area of L. lucidum increased from 0.1 to 4% between 1991 and 2011. Native tree individuals grew 65% less in exotic neighborhoods compared to native neighborhoods. Relative growth rate showed negative values under L .lucidum individuals for the abundant species Ocotea porphyria, Parapitadenia excelsa, Juglans austalis and Allophylus edulis, indicating competition; while less abundant species Terminalia triflora, Cupania vernalis and Blepharocalix saliscifolius showed positive growth values under L. lucidum suggesting a facilitation process. Thus, L. lucidum competes efficiently with some native tree species particularly with those abundant species that dominate the canopy.Conclusions. Ligustrum lucidum is invading post-agricultural secondary forests dominated by native tree species. While invading, L. lucidum competes with native abundant tree species that dominate the main structure of the forest canopy. As this invasive trend will likely increase in the near future, L. lucidum may alter forest structure, composition and dynamics as well ecosystem functioning.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240672,"idioma_id":4,"titulo":"Modelling respiration rate of soybean seeds (Glycine max (L.)) in hermetic storage.","resumen":"The dynamic of oxygen (O2) andcarbon dioxide (CO2) concentration was characterized in soybean (Glycine max (L.)) samples hermetically stored in glass jars at 15, 25 and 35C and 13, 15 and 17% moisture content (m.c., wet base). Two correlations were used for smoothing gasconcentration in time: linear and exponential. Then, the respiration rate ateach temperature and m.c. combination was calculated as storage time progressedand oxygen was consumed and two predictive models for respiration were proposed:Model I (temperature and m.c. dependent) and Model II (temperature, m.c. and oxygendependent). It was observed that respiration rate increased with storage m.c.and temperature. However, respiration rate was not mainly affected by O2 until a critical concentration limit of about 2% was reached. Respiration rates werefrom 0.341 to 22.684 mg O2\/(kgDM d) and from 0.130 to 20.272 mgCO2 \/(kgDM d)for a range of storage condition of 13e17% m.c. and15e35C temperature. The respiration rate of soybean seeds obtained in this study resulted significantly lower than the ratesreported in the literature for other grains at similar temperature and aw (water activity) storage condition. For hermetic storage simulations in which O2concentrationis not expected to drop below 2%, the simplest model (Model I) could be used,but if the O2 concentration of the hermetic system is expected to be depleted, ModelI would under estimate the time at which O2 is consumed, and thus a model with O2 dependency is recommended instead (Model II).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240673,"idioma_id":4,"titulo":"Validation of kinetic modeling of progesterone release from polymeric membranes","resumen":"Mathematical modeling in drug release systems is fundamental in development and optimization of these systems, since it allows to predict drug release rates and to elucidate the physical transport mechanisms involved. In this paper we validate a novel mathematical model that describes progesterone (Prg) controlled release from poly-3-hydroxybutyric acid (PHB) membranes. A statistical analysis was conducted to compare the fitting of our model with six different models and the Akaike information criterion (AIC) was used to find the equation with best-fit. A simple relation between mass and drug released rate was found, which allows predicting the effect of Prg loads on the release behavior. Our proposed model was the one with minimum AIC value, and therefore it was the one that statistically fitted better the experimental data obtained for all the Prg loads tested. Furthermore, the initial release rate was calculated and therefore, the interface mass transfer coefficient estimated and the equilibrium distribution constant of Prg between the PHB and the release medium was also determined. The results lead us to conclude that our proposed model is the one which best fits the experimental data and can be successfully used to describe Prg drug release in PHB membranes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240676,"idioma_id":5,"titulo":"E-Book: Atlas de histología y Anatomía vegetal","resumen":"El objetivo de este trabajo es producir un material didáctico  digital  interactivo  de  histología  y anatomía  vegetal  destinado  a  estudiantes  deIngeniería Agronómica y carreras biológicas afines. Para ello se recolectaron 105 especies vegetales principalmente del centro de Argentina.Las muestras de hoja, tallo, raíz, antera y gineceo fueron fijadas en F.A.A. y procesadas para la obtención de preparados histológicos. Se llevaron a cabo distintas técnicas de tinción de órganos.Estos  fueron  fotografiados  con  una  cámara Moticam  2000  conectada  a  un  microscopio  Axiolab Zeiss. El atlas está organizado en los siguientes  capítulos:  el  primero  presenta  las imágenes  de  las  especies  involucradas  en  el material, el segundo contiene la anatomía de cada órgano, el tercero los distintos tejidos y el cuarto la anatomía de los órganos según el ambiente  donde  se  desarrolla  la  especie.  El material  permite  con  el  posicionamiento  del mousse acceder desde el nombre e imagen de la especie hacia sus órganos, tejidos y ambiente donde crecen, permitiendo al estudiante navegar de  acuerdo  a  sus  intereses  particulares.  Este e-book estará disponible de manera libre y gratuita en la plataforma de la editorial UniRío de la Universidad Nacional de Río Cuarto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240681,"idioma_id":4,"titulo":"Enhancing the coating properties of acrylic\/casein latexes with high protein content","resumen":"Casein-derived materials are highly attractive as a consequence of their environmental friendliness and excellent film-forming properties. Due to the casein hydrophilicity, films containing a large protein content are highly susceptible to water, thus limiting their use in coating applications. A novel approach for synthesizing waterborne acrylic?casein latexes with large content of protein and high degree of compatibilization between both components is presented. The employed synthesis strategy involves the use of a highly methacrylated casein in an emulsifier-free emulsion polymerization of acrylic monomers with the aim of controlling both the fraction of grafted biomaterial and the amount of acrylic chains linked onto the protein backbone. The performance of the resulting materials was evaluated in a water-based coating application. The used methacrylation approach allowed the maximum compatibilization of 33% of casein in the hybrid polymer. The as-obtained casein-derived films were proven to exhibit superior water resistance, which would open a new possibility for designing biobased coatings in several fields.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240682,"idioma_id":4,"titulo":"Temperature responsive PEG-based polyurethanes 'à la carte'","resumen":"Temperature responsive polymers able to alter their chemical or physical properties have been extensively investigated. Most of these polymers have an alkane polymer backbone with only carbon-carbon bonds. In this sense, the design of thermoresponsive polymers not only with sharp transition temperatures but also possessing hydrolizable linkages such as esters, carbonates or urethanes in the main backbone are highly desired. Here we show a library of thermoresponsive cationic and anionic polyurethanes synthesized by copolymerization of isophorone diisocyanate with poly(ethylene glycol) and ionic diols. These polyurethanes exhibit lower critical solution temperatures (LCST) that can be easily tuned from 20 °C to 60 °C by altering the polyurethane composition. Our findings show that LCST temperature could be reduced by the using poly(ethylene glycol) of lower molecular weight and\/or increasing the hydrophobicity of the employed ionic diol. We also demonstrated that the thermoresponsive behavior could be translated to hydrogels based on those ionic polyurethanes. These ?a la carte? thermoresponsive polyurethanes materials present a great potential in the biomedical field due to the presence of hydrolizable linkages in the main polymer backbone.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240688,"idioma_id":5,"titulo":"La historiografía y la construcción del pasado en Chubut: representaciones de la colonización galesa y su relación con los pueblos originarios en tres libros de historia provincial","resumen":"Este artículo se propone analizar de qué forma se construyeron las representaciones respecto a lacolonización galesa en Patagonia, iniciada en 1865, en tres libros de historia de la provincia delChubut, publicados entre las décadas de 1960 a 1990. Prestando atención al rol dado a esta experienciacolonizadora en la futura formación de una historia y una ?identidad provincial? chubutense, nuestroprincipal propósito será analizar las lecturas respecto al contacto y la relación entre los colonos galesesy los pueblos originarios de la zona. Consideramos que las obras ayudaron a cimentar el mito de laconvivencia pacífica, pero manteniendo siempre una evidente dicotomía entre lo galés como símbolocivilizatorio y lo indígena como lo barbárico que, de una forma u otra, se encaminaría hacia laextinción.Palabras","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240695,"idioma_id":4,"titulo":"Conceptual Considerations of Work Passion","resumen":"Work passion is defined as a persistent state of desire based on both cognitive and affective appraisals of one´s job. According to Vallerand´s dualistic model, there are two types of passion called as harmonious passion and obsessive passion. Given its novelty in the field of organizational psychology, the aim of the present study is to provide a systematic literature review of the work passion construct. Specialized bases were examined obtaining 61 scientific publications corresponding to the period 2003-2017. The analysis of the literature shows that both types of passion are associated with dissimilar results, as well as different contextual and dispositional antecedents. To date, there is only one scale available to measure the construct, whichhas been adapted to diverse cultural contexts. The article concludes with some suggestions forfuture research on the subject.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240696,"idioma_id":4,"titulo":"Distribution of FMR1 and FMR2 repeats in Argentinean patients with primary ovarian insufficiency","resumen":"The premutation state of FMR1 (Fragile X Mental Retardation 1) has been associated with primary ovarian insufficiency (POI), and is the most common known genetic cause for 46,XX patients. Nevertheless, very few studies have analyzed its frequency in Latin American populations. Additionally, a relationship between alleles carrying a cryptic microdeletion in the 5?UTR of FMR2 and the onset of POI has only been studied in one population. Our aim was to analyze the incidence of FMR1 premutations and putative microdeletions in exon 1 of FMR2 in a cohort of Argentinean women with POI. We studied 133 patients and 84 controls. Fluorescent PCR was performed, and the FMR2 exon 1 was further sequenced in samples presenting less than 11 repeats. We found the frequency of FMR1 premutations to be 6.7% and 2.9% for familial and sporadic patients, respectively. Among controls, 1\/84 women presented a premutation. In addition, although we did not find microdeletions in FMR2, we observed a change (T>C) adjacent to the repeats in two sisters with POI. Given the repetitive nature of the sequence involved, we could not ascertain whether this represents a single nucleotide polymorphism (SNP) or a deletion. Therefore, a relationship between FMR2 and POI could not be established for our population.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240697,"idioma_id":4,"titulo":"Arbuscular mycorrhiza reduces the negative effects of M. phaseolina on soybean plants in arsenic-contaminated soils","resumen":"All crops are negatively affected by several abiotic and biotic stresses, alone or jointly; however, some microorganisms, such as arbuscular mycorrhizal fungi (AMF), are able to alleviate them. Here, we investigated the effects of the AMF Rhizophagus intraradices (N.C. Schenck & G.S. Smith) C. Walker & A. Schüßler on soybean plants (Glycine max L.) grown in arsenic-contaminated soils and infected by the fungus Macrophomina phaseolina (Tassi) Goid., (charcoal rot). Two pots experiments were carried out in a glasshouse, and three levels of As (0, 25, and 50 mg As kg&#8722;1) were evaluated. Plant and mycorrhizal parameters, disease severity, glomalin content, and arsenic content in roots and leaves were analyzed. Both arsenic and the pathogen negatively affected soybean biomass and morphological parameters. Moreover, both stresses adversely affected mycorrhizal symbiosis. Low levels of AMF colonization and vitality were observed in high As concentration and in pathogen presence; however AMF inoculation not only reduced the disease but also lowered arsenic accumulation rate in soybean biomass. On the other hands, disease severity was reduced by arsenic. Total glomalin content, produced by the AMF was increased in arsenic-enriched substrates, but was not modified in the presence of the pathogen. Increases in glomalin production could be one of the reasons by which soybean plants accumulate low arsenic amounts while the competition between AMF and the pathogen plays an important role in reducing the disease severity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240705,"idioma_id":4,"titulo":"Floral and pollination biology, breeding system and nectar traits of Callistemon citrinus (Myrtaceae) cultivated in India","resumen":"This study reports the influence of habitat on floral (flower and nectar characteristics, phenology) and pollinationbiology (flower visitors and breeding system) on Callistemon citrinus (syn. Callistemon lanceolatus), an Australianspecies of family Myrtaceae. In India, this small ornamental tree is cultivated in gardens, avenues and road sidesand flowers throughout the year. At Agra (Uttar Pradesh, northern India) this species flowers twice a year(February?May and August?November). Flowers open early in the morning and can be characterized asprotandrous for a brief period. Fresh open flowers presented ca. 25% of total produced nectar. Nectar sugar compositionconsisted of only glucose and fructose. A wide array of visitors (honey bees (Apis dorsata), butterflies,wasps, ants, moth, hover flies, several birds and Indian palm squirrel) visit flowers either for pollen or nectaror for facilitating self- and cross-pollination by their intra- and inter-tree movements. Among these, honeybees are dominant in number and in the amount of pollen on their body,while butterflies, ants, wasps, sunbirds,parrots, oriental white-eye sparrow and squirrels forage only for nectar and can be considered occasional pollinatorsor nectar thieves. Although flowers are highly visited, nectar in standing crop showed that flower visitorsdid not consume the total nectar produced. Nectar replenishment decreased with age in both bagged- andexposed flowers, showing the capability of secreting nectar after removal during the entire flower lifetime.Experimental hand-pollinations showed that naturalized C. citrinus fruits matured through autogamy,geitonogamy or xenogamy as was reported for native Australian populations. C. citrinus displays an interestingreproductive strategy, shows phenotypic plasticity of flowering periodicity and interacts with a generalized pollinatorsystem, attracts a wide array of animal species with a conspicuous amount or replenished nectar after removals,and uses both compatibility strategies ? xenogamy and autogamy ? to ensure successful pollination andseed production at native or naturalized habitats.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240706,"idioma_id":4,"titulo":"Fungal diversity is negatively affected by habitat fragmentation: a meta-analysis.","resumen":"Fungi are ubiquitous organisms around the world with important roles in ecosystem functioning and services, but knowledge about how habitat fragmentation affect fungal diversity is spread in different trophic groups, studied regions and experimental approaches. We performed a meta-analysis to synthesize the available information to glimpse general patterns of habitat fragmentation effects on fungal diversity. The habitat fragmentation process consistently affect fungal diversity through isolation, area size and increasing edge proportion, albeit this trend may differ between both, the type of response variable and fungal groups with different nutritional habits. Together, this knowledge may allow designing accurate strategies for sustainable land uses and landscape management in face of worldwide habitat fragmentation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240707,"idioma_id":4,"titulo":"DOES AVIAN GUT PASSAGE FAVOUR SEED GERMINATION OF WOODY SPECIES OF THE CHACO SERRANO WOODLAND IN ARGENTINA?","resumen":"Frugivorous birds are key dispersal agents of many plant species and also mayfacilitate seed germination after gut-passage. However, the general effects of gut-passage on seed germination are still not clear, with positive, negative and neutral effects reported on seed germination. We evaluated seed germination of seven bird-dispersed plant species of the Chaco Serrano Woodland in Córdoba, Argentina: Celtis ehrenbergiana, Condalia spp., Lantana camara, Lithraea molleoides, Lycium cestroides, Schinus fasciculatus and Zanthoxylum coco. We compared germination percentages and germination speed among seeds ingested by birds, manually extracted seeds, and seeds from intact fruits in order to understand which mechanisms are acting on bird gut-passed seeds. For six plantspecies, the action of frugivorous birds increased seed germination percentages and provides faster germination, either through scarification, deinhibition, or through combined mechanisms. Our results contribute to better understand the mechanisms acting on bird gutpassed seeds. Also, we show the pivotal role that frugivorous birds exert on the seed germination of native woody plant species in the threatened ecosystem of Chaco Serrano Woodland.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240708,"idioma_id":4,"titulo":"Synthesis of novel quinoline-based 4,5-dihydro-1H-pyrazoles as potential anticancer, antifungal, antibacterial and antiprotozoal agents.","resumen":"A new series of N-substituted 2-pyrazolines 9a-f, 10a-f, 11a-f, 12a-f and 13a-f were obtained from the cyclocondensation reaction of [(7-chloroquinolin-4-yl)amino]chalcones 8a-f with hydrazine hydrate and its derivatives. Fourteen of the synthesized compounds including the starting chalcones wereselected by US National Cancer Institute (NCI) for testing their anticancer activity against 60 different human cancer cell lines, with the most important GI50 values ranging from 0.28 to 11.7 uM (0.13-6.05 ug\/mL) and LC50 values ranging from 2.6 to > 100 uM(1.2 to > 51. 7 ug\/mL), for chalcones 8a,d and pyrazolines10c,d. All compounds were assessed for antibacterial activity against wild type and multidrug resistant gram negative and gram positive bacteria, with MIC values ranging from 31.25 to 500 ug\/mL. Additionally, the novel compounds were tested for antifungal and antiparasitic properties. Although these compounds showed mild activity against Candida albicans, chalcones 8a and 8e showed high activity against Cryptococcus neoformans with MIC 50= 7.8 ug\/mL. For anti-Plasmodium falciparum activity the 2-pyrazoline 11b was the most active with EC50= 5.54 ug\/mL. Regarding the activity against Trypanosoma cruzi, compound 10a was highly active with EC50 = 0.70 ug\/mL. Chalcone 8a had good activity against Leishmania panamensis amastigotes with EC50= 0.79 ug\/mL.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240709,"idioma_id":4,"titulo":"Unraveling early events in the Taphrina deformans - Prunus persica interaction: an insight into the differential responses in resistant and susceptible genotypes","resumen":"Leaf peach curl is a devastating disease affecting leaves, flowers and fruits caused by the dimorphic fungus Taphrina deformans. To gain insight into the mechanisms of fungus pathogenesis and plant responses, leaves of a resistant and two susceptible P. persica genotypes were inoculated with blastospores (yeast), and the infection was monitored during 120 hpi. Fungal dimorphism to the filamentous form and induction of ROS, callose synthesis, cell death, and defense compound production was observed independently of the genotype. Fungal load significantly decreased after 120 hpi in the resistant genotype while the pathogen tended to grow in the susceptible genotypes. Metabolic profiling revealed a biphasic re-programming of plant tissue in susceptible genotypes, with an initial stage which provides metabolites that allow the reproduction of the yeast and a second which facilitates development of the hyphae. Transcriptional analysis of PRs and plant hormone-related genes indicated that PR proteins are involved in P. persica defense responses against T. deformans and that salicylic acid is induced in the resistant genotype. Conducted experiments allowed the elucidation of common and differential responses in susceptible vs resistant genotypes, and thus allows us to construct a picture of early events during T. deformans infection.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240710,"idioma_id":4,"titulo":"Comparative proteomic and metabolomic studies between Prunus persica genotypes resistant and susceptible to Taphrina deformans suggest a molecular basis of resistance","resumen":"The worldwide-distributed leaf peach curl disease is caused by the biotroph Taphrina deformans. To characterize the plant-fungus interaction, resistant and susceptible Prunus persica genotypes grown in the orchard were studied. Asymptomatic leaves were tested for fungal presence. In all resistant leaves analyzed the fungus was not detected. Conversely, leaves from the susceptible genotype were categorized according to the presence or absence of the pathogen. Comparative metabolomic analysis disclosed the metabolite composition associated with resistant and susceptible interactions, and of compounds involved in fungal growth inhibition such as chlorogenic acid, whose in vitro antifungal activity was verified in this work. Differential proteome studies revealed that chloroplasts are important site of plant defense responses against T. deformans. Members of the Bet-v1-like family protein differentially responded to the pathogen. Extracellular pathogenesis-related proteins, evaluated by qRT-PCR, and an enone oxidoreductase are constitutively present in leaves of resistant trees and could be related to fungal resistance. This study is a global view of the changes in the metabolome, proteome and transcripts related to plant defense in naturally infected leaves of susceptible plants during the asymptomatic stage. Additionally, it provides clues to the successful molecular mechanisms operating in resistant plants, which neither develop the disease nor harbor the pathogen.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240711,"idioma_id":5,"titulo":"Una mirada global sobre la influencia de los patrones alimentarios en las enfermedades cardiovasculares.","resumen":"Antecedentes: las enfermedades cardiovasculares (ECV) constituyen la primera causa de muerte a nivel global. Si bien alimentos y nutrientes han sido relacionados a la promoción o prevención de ECV, analizar los componentes dietarios en forma aislada genera resultados parciales y descontextualizados. Objetivo: analizar el concepto y surgimiento del patrón alimentario (PA) y la evidencia científica sobre su influencia en la ECV. Materiales y métodos: se realizó una búsqueda sistemática de publicaciones en bases de datos electrónicas MEDLINE, EMBASE Lilacs y Scielo. Se incluyeron aquellos artículos que contenían las palabras claves o una combinación de ellas, durante 2000-2016.  Resultados y conclusiones: independientemente de la región geográfica estudiada, un PA saludable, prudente o mediterráneo, rico en frutas, verduras, granos enteros, legumbres y pescado, se asoció a menor riesgo de ECV, mientras que un PA occidentalizado o de alimentos procesados, abundante en carnes rojas y procesadas, granos refinados, frituras y dulces se correlacionó positivamente con mayor riesgo de mortalidad por ECV, infarto agudo de miocardio, accidente cerebrovascular y cardiopatías isquémicas. El análisis de PA constituye una herramienta eficaz para formular recomendaciones alimentarias acordes a la cultura alimentaria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240718,"idioma_id":5,"titulo":"El sentido social y cultural de la inclusión de las tecnologías de la información y la comunicación en las prácticas de la enseñanza","resumen":"El artículo presenta algunos resultados de una investigación orientada a generar interpretaciones sobre la inclusión de las tecnologías en las prácticas de la enseñanza. Se enfoca particularmente en una muestra obtenida en el marco de la implementación del Programa Conectar Igualdad en el nivel medio de las escuelas de gestión estatal de Argentina. El estudio de treinta y dos relatos didácticos construidos a partir de entrevistas y observaciones de clases de docentes que realizaron adopciones tempranas de la tecnología puesta a disposición nos permitió reconocer el sentido social y cultural de estas inclusiones, con expresiones concretas en el plano de las prácticas llevadas a cabo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240719,"idioma_id":5,"titulo":"Una Rita que educa a todas\/os","resumen":"Como Merlí, el profesor catalán de la serie homónima, Rita es una maestra que rompe el molde. Nos parece importante en estos días en los que se acerca el inicio de clases, analizar por qué nos interesa tanto y qué rasgos reconocemos en un personaje de ficción para poder pensarnos a nosotros mismos. Con su ?uniforme? de tacos, casi siempre, jean, remera, camisa y campera de cuero Rita remonta vuelo en los pasillos de una escuela pública danesa. Con su largo cabello al viento atraviesa el hermoso parque escolar que separa su casa de la escuela con algunos árboles. Hay algo de su andar, decidido y desafiante, que nos atrapa. Su notable presencia caminando por los pasillos de la escuela conecta las aulas con las diversas historias que la ficción va entretejiendo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240724,"idioma_id":5,"titulo":"Sobre caminos transitados. La cultura del patrimonio y la arquitectura del presente","resumen":"En las últimas décadas, el tema de la preservación del patrimonio se ha constituido en una preocupación propia de la cultura arquitectónica contemporánea. El interés legítimo, tanto de la preservación como de la arquitectura misma, hoy tiene que ver, además,  con una toma de posición frente a la lógica homogeinizadora de las industrias culturales y a la necesidad de recomponer el sentido de ?lo común?, de ?lo propio?.En consecuencia, las relaciones entre preservación del patrimonio y obra nueva son objeto de numerosos estudios y propuestas. Los criterios contemporáneos sustentan ampliamente la incorporación de los sitios o edificios preexistentes a los proyectos de intervención, asumiendo esta relación como una contribución a la caracterización de áreas y al fortalecimiento de la imagen de la ciudad.En tanto que la planificación urbana y el proyecto de arquitectura se perciben como instrumentos de innovación y dinamización de la ciudad, sus relaciones con la creciente valorización del patrimonio histórico presentan, en principio, un estado de conflicto potencial, que puede ser incorporado al proyecto, a la ciudad y a la región con un signo positivo, esto es, como factor de reactivación y desarrollo.Crear o fortalecer este sentido positivo de la preservación, implica un desafío para profesionales e inversores y para los funcionarios de la gestión pública: aquello que se consideraba un aparente obstáculo para la resolución proyectual, para el negocio inmobiliario, o para la planificación urbana, se revierte ahora, desde el proyecto,  en una condición de posibilidad.Equipo docente: Dra. Arq. Bibiana Cicutti, Arq. Gabriel Asorey (Coordinador 2014); Arq. Miguel Garrofé (Coordinador 2015), Arq. Andrea Cignacco, Estudiantes auxiliares: Guillermina Aguilera Baglietto, Antonella Serri, Agustina Berrueta","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240725,"idioma_id":5,"titulo":"Animaciones, vídeos y códigos: herramientas para mejorar la comprensión de conceptos científicos. Revista Argentina de la Ingeniería","resumen":"ResumenEste escrito muestra parte de lo producido en el marco de la investigación que engloba desarrollo, uso y evaluación de herramientas tecnológicas para el aprendizaje de conceptos de química para primer año de ingeniería en la universidad y de matemática para el último año del secundario. Por un lado se generó una animación referida a Equilibrio Químico para favorecer el aprendizaje de contenidos abstractos y se evaluó el impacto producido. Por el otro, se produjeron vídeos con clases grabadas y guías de estudio incorporando códigos de respuesta rápida. La metodología utilizada para recoger datos fue una combinación de encuestas con preguntas abiertas y cerradas, y técnica focusgroup. Los resultados muestran que la animación logró desarrollar una mejor comprensión de conceptos y generó mayor disposición para el aprendizaje. Los estudiantes secundarios rescatan grabación de clases, e implementación de códigos, más no consideran al aula virtual como herramienta de comunicación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240726,"idioma_id":5,"titulo":"Desarrollo de contenidos para el aprendizaje m-learning","resumen":"Resumen?Los smartphones se han convertido en accesorios vitales y han cambiado la manera de vivir, de informar y de comunicarse, aunque no siempre se los utiliza de manera eficaz para el aprendizaje de contenidos científicos e ingenieriles. La posibilidad de acceder a la información en cualquier lugar o cualquier momento desde un dispositivo móvil, la interacción con pares o familiares, como así también el poder generar oportunidades estructuradas de aprendizaje desde una variedad de fuentes, son también realidades. Los autores que presentan este artículo conforman un equipo de investigación educativa abocados al aprendizaje y enseñanza de la ciencia y la ingeniería desde hace más de diez años; como resultado de esos estudios se advirtió la necesidad de poner en práctica algunas metodologías utilizando los dispositivos móviles. El objetivo es lograr aprendizajes significativos y generar algunas competencias en estudiantes universitarios de primer año y del último año del preuniversitario, contribuyendo al incentivo de vocaciones relacionadas a la ingeniería. Como resultado del desarrollo se obtuvieron paquetes de materiales didácticos conformados por guías, videos, clases grabadas y bibliografías conectadas a través de códigos QR, y una App especialmente diseñada a las que se accede desde los smartphones","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240729,"idioma_id":4,"titulo":"A General Reaction Mechanism for Carbapenem Hydrolysis by Mono- and Binuclear Metallo-&#946;-lactamases","resumen":"Carbapenem-resistant Enterobacteriaceae threaten human health, since carbapenemsare last resort drugs for infections by such organisms. Metallo-&#946;-lactamases (M&#946;Ls) are the main mechanism of resistance against carbapenems. Clinically approved inhibitors of MBLs are currently unavailable as design has been limited by the incomplete knowledge of their mechanism. Here we report a biochemical and biophysical study of carbapenem hydrolysis by the B1 enzymes NDM-1 and BcII in the bi-Zn(II) form, the mono-Zn(II) B2 Sfh-I and the mono-Zn(II) B3 GOB-18. These M&#946;Ls hydrolyse carbapenems via a similar mechanism, with accumulation of the same anionic intermediates. We characterize the Michaelis complex formed by mono-Zn(II) enzymes, and we identify all intermediate species, enabling us topropose a chemical mechanism for mono and binuclear M&#946;Ls. This common mechanismopen avenues for rationally designed inhibitors of all M&#946;Ls, notwithstanding the profound differences between these enzymes? active site structure, &#946;-lactam specificity and metal content","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240730,"idioma_id":5,"titulo":"El mercado como una esfera de la libertad social","resumen":"Axel Honneth haintentado explicar las luchas por el reconocimiento de nuestras sociedadescontemporáneas en términos de pretensiones normativas para el logro de unaautorrelación no distorsionada. Sin embargo, ha recibido numerosas objecionesde parte de Nancy Fraser, la más importante de las cuales es la necesidad decomplementar las exigencias de reconocimiento con las de redistribución debienes y servicios. Consecuentemente, Honneth ha reelaborado su teoría, paradar cuenta de que el mercado es una esfera de la libertad social, es decir queestá estructurado para garantizar la complementariedad y el reconocimientomutuo. Sin embargo, Honneth no logra tampoco demostrar esta tesis. Por lo tanto,su teoría no logra fundamentar pretensiones normativas de reformular las reglasdel mercado.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240731,"idioma_id":5,"titulo":"Proyecto contemporáneo. El lugar de la Historia","resumen":"Editora invitada para este numero.Autora de dos textos uno introductorio y otro correspondiente a la sección La Historia de la Arquitecturaes...Proyecto contemporaneo. el lugar de la HistoriaHemos advertido en artículos y editoriales de revistas de arquitectura publicados en los últimos años, una suerte de ?celebración? de la práctica profesional en sí misma por sobre el discurso crítico, referencial. Condición -detectada tanto en la bibliografía especializada como en los comentarios de los propios proyectistas- que, acorde con el desencanto generacional sobre los alcances de las posiciones teóricas determinantes, fue silenciando el debate y la crítica hasta hacerla ?desaparecer por completo?. En su reemplazo, la figura del ?productor?, del ?hacedor? fue cobrando fuerza y prestigio, relegando la preeminencia de la Teoría   y la Historia, otrora fundamento legitimador de las experiencias.Frente a un modo de hacer y pensar la Arquitectura contemporánea que se nos exhibe como sumergida en un puro presente y que pareciera que soslaya ?o niega- su vinculación con el pasado lanzando desafíos al futuro, nos propusimos en este número de A&PCONTINUIDAD, indagar acerca de cuál es ?el lugar de la historia? en el proyecto contemporáneo?Es necesario reforzar los estudios históricos en las escuelas de Arquitectura?...Son útiles al proyectista aunque no directamente productivos? Lejos de optar por una u otra posición, propusimos a nuestros colegas transitar ?al decir de I. de Solá Morales-, las fronteras que ambiguamente reúnen prácticas históricas, prácticas críticas y prácticas arquitectónicas (Sola Morales, 2003,255) y sobre todo, cómo éstas operan en la toma de decisiones proyectuales y se articulan en los Planes de Estudio, en la enseñanza de la disciplina, en las distintas esferas de la investigación académica, consagración institucional, etc.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240733,"idioma_id":5,"titulo":"Contando la Historia\/ Entrevista a J. F. Liernur","resumen":"Dedicado a Historia de la Arquitectura","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240734,"idioma_id":5,"titulo":"Gestos didácticos en el desarrollo de un Recorrido de Estudio e Investigación en el nivel universitario relativo al Cálculo: el funcionamiento de las dialécticas","resumen":"En este trabajo se presentan resultados parciales sobre la introducción en el nivel universitario de una enseñanza basada en la investigación, mediante el dispositivo didáctico Recorridos de Estudio e Investigación (REI). El REI propuesto parte de la pregunta Q0: ¿Cómo calcular los costos en un micro-emprendimiento? Se realizaron implementaciones en dos cursos de Matemática del primer año de una universidad pública argentina conformados por estudiantes (N = 73) que cursan carreras vinculadas a la Economía y a la Administración deEmpresas. Se observan diferencias entre una y otra implementación, relacionadas con los gestos didácticos que laTAD denomina dialécticas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240735,"idioma_id":6,"titulo":"Étude des fonctions algébriques dans le cadre d?un Parcours d?Étude et de Recherche dans l?école secondaire : le cas des fonctions rationnelles","resumen":"Cette recherche propose de mettre en place la Pédagogie de la Recherche et du Questionnement du Monde dans des classes de mathématiques de l?école secondaire argentine. On présente quelques résultats d?introduire un Parcours d?Étude et Recherche (PER) monodisciplinaire avec élèves de 14-16 ans. Dans ce travail nous décrivons l?Organisation Mathématique de Référence (OMR), et les résultats obtenus le long d?une étude longitudinale qui dure deux ans avec les mêmes étudiants. Nous analysons les caractéristiques de l?Organisation Mathématique (OM) reconstruitepar rapport à l?activité mathématique qui se développe dans le PER.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240736,"idioma_id":4,"titulo":"Characteristics and changes in the mathematics textbooks for the secondary school in Argentina along 67 years.","resumen":"This work analyses the changes in the relationship between arguing and images from the mathematics textbooks for the secondary school in Argentina (students 12-17 years old) along 67 years. The textbooks have been published in the period 1940 thru 2007. The analysis is done by (N=137) textbooks based on three meta-categories in an inductive way. These meta-categories are: characteristics of the arguing, relationship between images and arguing as well as characteristics of the textbooks (the date of publishing, the epistemological conceptions about mathematics and the educational level which the textbook is oriented). A factorial analysis of multiple correspondences was performed to find the main similarities and differences between the textbooks and to make a cluster analysis and one possible classification. The main differences are given by the changes in the epistemological conception of mathematics and in the characteristics of the images, especially in the newest edition books.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240737,"idioma_id":5,"titulo":"La utilidad de la matemática y su enseñanza en la escuela secundaria de adultos: el punto de vista de los estudiantes","resumen":"Este trabajo integra una investigación acerca de qué matemática habría que enseñar en la Escuela Secundaria de Adultos en Argentina. Se presentan los resultados de una exploración asociada con la utilidad de la matemática escolar y su enseñanza en la Escuela Secundaria de Adultos desde el punto de vista de los alumnos. Se describen los resultados de cinco focus groups realizados con estudiantes adultos para la elaboración de una encuesta. Los datos se analizan con una técnica cualitativa basada en una categorización inductiva y otra léxico-métrica. Los resultados muestran que los estudiantes atribuyen poca utilidad a los saberes matemáticos estudiados, así como la existencia de una gran distancia entre la enseñanza actual de la matemática en la Escuela Secundaria de Adultos y su objetivo de un brindar un aprendizaje para la vida. Se discute la contribución de ambos análisis a este tipo de investigaciones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240738,"idioma_id":5,"titulo":"'Enseñanza de la matemática por recorridos de estudio e investigación: indicadores didáctico-matemáticos de las 'dialécticas''.","resumen":"This paper proposes and describes an analysis methodology based on the formulation of a set of didactic-mathematical indicators of the ?dialectics? of study and research. These indicators were constructed based on the data obtained from de design, implementation and evaluation of a study and research path (SRP). The SRP?s initial questions are connected to market equilibrium in a microeconomic model of the supply and demand. Two implementations were developed in the last year of the Argentine secondary level (16-17years) (N = 60). The teacher proposed to the students the following type of questions: How to determine the market equilibrium? If the parameters of the model are modified: How to describe the variation of the point of equilibrium? How much does the point of equilibrium change exactly in each case? We conclude that the most identified dialectics are: the individual and collective, theme and out of theme, study and research, praxeological analysis-synthesis and didactic of analysis-synthesis, and the dialectic of black boxes and clear boxes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240739,"idioma_id":4,"titulo":"DEVELOPMENT OF RESEARCH AND STUDY PATHS IN THE  PRE-SERVICE TEACHER EDUCATION","resumen":"In this paper, we present results of an implementation of research and study course carried out into a teacher training course in the University. The framework of the Anthropological Theory of the Didactic (ATD) is adopted, and a co-disciplinary Research and Study Path (RSP) whose generative question requires studying mathematics and physics together is carried out by training teachers of Mathematics at University. Some conclusions concerning on the conditions, restrictions and relevance of introducing the RSP in teachers training courses at the university are presented.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240740,"idioma_id":5,"titulo":"Estudiantes adultos y sus representaciones sociales acerca de la escuela secundaria de adultos: una exploración utilizando la técnica de grupos de enfoque","resumen":"Se presentan los resultados de cinco focus group realizados con estudiantes de la Escuela Secundaria de Adultos (ESA) para relevar y caracterizar sus intereses para asistir a esa institución. Se exploran sus Representaciones Sociales (RS) acerca de la función social y personal de la ESA. Como primera aproximación a la problemática, a partir del análisis de las transcripciones de los focus group implementados y del software ATLAS.ti®, se realizó una categorización inductiva de las respuestas. Los resultados indican que las RS identificadas no permiten a estos estudiantes analizar críticamente si la escuela los encamina a conseguir sus objetivos. Los resultados constituyen insumos para realizar una encuesta. También indican la necesidad considerar a los intereses y a las RS de los adultos entre los factores que se deben tener en cuenta para repensar la ESA.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240742,"idioma_id":5,"titulo":"Análisis de las defunciones por accidentes de tránsito en los registros oficiales de La Rioja - Argentina. Periodo 2011 - 2013","resumen":"Los accidentes de tránsito implican la pérdida de 1,3 millones de personas en el mundo cada año, convirtiéndose en una de las principales causas de defunción y la principal causa en la población joven entre 15 y 29 años. En este trabajo, descriptivo y exploratorio, se indagó acerca de la situación de la mortalidad en la provincia de La Rioja- Argentina, entre los años 2011 y 2013 provocada por los accidentes de transporte e intentó identificar si existió subregistro de las defunciones por esta causa en los registros oficiales. Para ello, utilizó como fuentes de datos el registro de defunciones, provisto por el Ministerio de Salud, y una base de datos confeccionada Ad Hoc a partir de los registros periodísticos de los siniestros viales ocurridos en la provincia. A partir de la comparación de estas fuentes se ha identificado un subregistro de muertes por accidentes de transporte del 57% en las estadísticas vitales. Ambos registros coincidieron en que estos eventos afectaron principalmente a los hombres menores de 45 años. La mayoría de los fallecidos conducía motocicleta al momento del siniestro, ocurrido principalmente en zona urbana. Esto últimos datos no se encontraron en los registros oficiales. Este aporte puede servir de base para reforzar ciertas políticas públicas tendientes a reducir estas muertes evitables.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240756,"idioma_id":5,"titulo":"La adversidad en el psicoanálisis y en la educación","resumen":"Artículo desarrollado en el marco del Seminario Abierto Crear en la adversidad: Infancias, entre Educación, Salud y Derechos, realizado en la ciudad de Mar del Plata, durante los días 20 al 22 de abril 2017, nos ubica ante un QuéHacer en la adversidad: tejido de redes de sostén.http:\/\/www.infeies.com.ar\/063.html","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240757,"idioma_id":4,"titulo":"The use of environmental sustainability criteria in industrial processes","resumen":"In several Guest Editorials and earlier articles, the connection between climate change and industrial processes has been analyzed in detail. In this editorial, the connections between sustainability and industrial processes are briefly considered.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240758,"idioma_id":4,"titulo":"Atmospheric Particulate Matter Variability during 2014 at Buenos Aires City (Argentina) Comparing Ground-Based Measurements and Satellite Data","resumen":"Air pollution is a major environmental risk to health. In particular, exposure to high concentrations of small particulates (PM10 and PM2.5) is related to increased mortality and morbidity. In Argentina, only at Buenos Aires city (34.4° S 58.3° W), which together with the surrounding districts accounts for the 30% of the total country population, continuous measurements of air quality are carried out. Though ground-based stations provide very accurate PM concentration values, they have very limited spatial coverage and may not be sufficient to assess the level of population exposure. Satellite-based is a valid alternative to fill these observational gaps. In this work, the MODIS 3 km × 3 km AOD retrievals for 2014, for both Terra and Aqua, were employed to evaluate the spatio-temporal variation of atmospheric aerosols over Buenos Aires and its metropolitan area in a year period. The MODIS AOD dataset is validated using the AOD dataset reported by the CEILAP_BA AERONET station (34.5° S 58.5° W). Satellite data show some areas with higher AOD values throughout the year-period in which no PM monitoring is not actually being carried out. These areas correspond mainly to a west zone within Buenos Aires territory and two other areas, at west and south Buenos Aires districts. Buenos Aires local government and the surrounding districts should make an effort to expand the monitoring network in order to make it representative of the actual exposure to particulate matter of the whole population.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240759,"idioma_id":4,"titulo":"SO2 and Aerosol Evolution over the Very Clear Atmosphere at the Argentina Andes Range Sites of San Antonio de Los Cobres and El Leoncito","resumen":"The atmosphere at North-Central Argentina Andes range is exceptionally clear for the placement of astrophysical\/astronomical\/solar observatories (Piacentini et al., Advances Space Research, 2016). However, this region is part of the Pacific fire belt, due to the large number of active volcanoes. Consequently, the possibility of having strong sporadic emissions of different gases and aerosols needs to be investigated. In the present work, we analyze in particular the SO2 trace gas, since it can affect significantly the solar UVB (280?320 nm) radiation. Also, particulate matter can attenuate this radiation in the UV-visible ranges. One of the most significant contributions to volcanic eruptions that could arrive at the selected San Antonio de los Cobres (SAC) location is the near Lascar volcano. We used satellite images form the OMI\/KMNI\/Aura\/NASA satellite instrument, for deriving the intensity of the eruption at the SAC geographical point. An important eruption was that of the Puyehue\/ Cordón Caulle volcanic complex at Chile Patagonia, in June 2011. No significant influence on the other selected El Leoncito (LEO) location was registered. We present aerosol optical depth (AOD550) satellite data obtained with the Deep Blue Level 2 data provided by the SeaWiFS\/SeaStar\/NASA satellite instrument for SAC and LEO places, showing that AOD550 for the whole period is extremely low (0.0262 for SAC and 0.0266 for LEO). We also present ground atmospheric aerosol concentration measurements as a function of aerosol diameter with a high quality GRIMM laser instrument for some days of campaign performed in those sites.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240761,"idioma_id":5,"titulo":"Montealegre Iturra, Jorge: Carne de estatua: Allende, caricatura y monumento, Santiago de Chile, La Mandrágora, 2014","resumen":"Carne de estatua: Allende, caricatura y monumento constituye un aporte original y fundamental para los estudios sobre la cultura referidos al imaginario, la memoria y el humor gráfico debido a que aborda la figura de Salvador Allende desde la caricatura política publicada en diversos medios gráficos chilenos. Como lo advierte Montealegre en el primer capítulo del libro, la vida de Allendeha sido tratada desde su discurso político, sus motivaciones, su ideología, sus características psicológicas, el contexto histórico en el que actuó, la situación económica de su gobierno, entre otras; casi todas acompañadas de elementos iconográficos: fotos, afiches, etcétera. Sin embargo, ningún estudio había tomado las imágenes como objeto de estudio y menos las caricaturas publicadas sobre Allende.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240763,"idioma_id":4,"titulo":"A role for LAX2 in regulating xylem development and lateral-vein symmetry in the leaf","resumen":"XXX","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240764,"idioma_id":4,"titulo":"A uORF represses the transcription factor AtHB1 in aerial tissues to avoid a deleterious phenotype","resumen":"AtHB1 is an Arabidopsis (Arabidopsis thaliana) homeodomain-leucine zipper transcription factor that participates in hypocotyl elongation under short-day conditions. Here, we show that its expression is posttranscriptionally regulated by an upstream open reading frame (uORF) located in its 5´ untranslated region. This uORF encodes a highly conserved peptide (CPuORF) that is present in varied monocot and dicot species. The Arabidopsis uORF and its maize (Zea mays) homolog repressed the translation of the main open reading frame in cis, independent of the sequence of the latter. Published ribosome footprinting results and the analysis of a frame-shifted uORF, in which the repression capability was lost, indicated that the uORF causes ribosome stalling. The regulation exerted by the CPuORF was tissue specific and did not act in the absence of light. Moreover, a photosynthetic signal is needed for the CPuORF action, since plants with uncoupled chloroplasts did not show uORF-dependent repression. Plants transformed with the native AtHB1 promoter driving AtHB1 expression did not show differential phenotypes, whereas those transformed with a construct in which the uORF was mutated exhibited serrated leaves, compact rosettes, and, most significantly, short nondehiscent anthers and siliques containing fewer or no seeds. Thus, we propose that the uncontrolled expression of AtHB1 is deleterious for the plant and, hence, finely repressed by a translational mechanism.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240765,"idioma_id":5,"titulo":"Ambientes de aprendizaje y proyectos escolares con la comunidad","resumen":"La investigación propende a contribuir con posibilidades de trabajo de una matemática escolar que trascienda los compartimentos estancos de contenidos, las formas mecanizadas de aprehensión y las desvinculaciones con el contexto socio-cultural de los estudiantes. Sienta sus bases en los fundamentos de la Educación Matemática Crítica, particularmente en lo que concierne a ambientes de aprendizaje. El interés está puesto en explorar las potencialidades de proyectos interdisciplinarios como generadores de sentido para los conocimientos escolares. En este caso esto se realiza en el marco de acciones que vinculan a la universidad con la comunidad. En particular, a través de la elaboración de un molino para una pobladora rural (proyecto concluido) así como de un secadero solar para una escuela rural (proyecto en ejecución), estando involucrados estudiantes de niveles no universitarios (terciario en el primer caso y secundario en el segundo) en ambas acciones. Entre las principales contribuciones de este tipo de trabajo se resalta la 'resignificación' de los aprendizajes escolares y del propio sistema escolar por parte de todos los miembros de la comunidad educativa. También se procura identificar fortalezas y debilidades de la experiencia a efectos de elaborar lineamientos para futuros proyectos interdisciplinarios.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240766,"idioma_id":5,"titulo":"Concepciones docentes acerca de la Resolución de Problemas matemáticos en la escuela secundaria","resumen":"El presente estudio tuvo como objetivo principal indagar sobre las concepciones que docentes de matemáticas de escuelas secundarias de la ciudad de San Nicolás (Buenos Aires, Argentina) tienen respecto a la Resolución de Problemas en este nivel del sistema educativo. Este objetivo responde a los tres interrogantes que motivaron esta investigación: A qué consideran problema matemático; cuáles son las semejanzas y diferencias que señalan de una actividad matemática denominada problema de otra llamada ejercicio; cómo se caracterizan los problemas que suelen proponer a sus alumnos del nivel. Los resultados se presentan de acuerdo a las tres categorías de análisis: Concepción de problema matemático, concepción de ejercicios de matemáticas y características de los problemas con los que trabajan en clase.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240767,"idioma_id":5,"titulo":"Formación en geometría analítica para futuros profesores. Un estudio de caso desde el MKT","resumen":"Este artículo pretende determinar la formación que se ofrece a los futuros profesores en Matemática en la configuración del conocimiento matemático para enseñar (MKT) geometría analítica elemental. Aquí se analiza desde el aporte disciplinar de la asignatura Geometría I de una carrera de formación de profesores en Matemática de Argentina. La investigación, que se aborda mediante un estudio de caso, tiene un enfoque eminentemente cualitativo y alcance principalmente descriptivo. Los resultados revelan que todos los dominios del MKT se activaron en las clases de dicha asignatura aunque en distintas proporciones y diferentes niveles de profundidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240768,"idioma_id":5,"titulo":"Enseñar Matemática con un enfoque histórico en la escuela secundaria","resumen":"Esta investigación surge de inquietudes sobre la enseñanza de los números irracionales en cuarto año de la educación secundaria. La insatisfacción que los alumnos manifiestan durante el aprendizaje de este campo numérico y el desconocimiento de estos números luego de haberse impartido su enseñanza incentivaron a diseñar una propuesta didáctica basada en un enfoque histórico. La intención fue caracterizar la manera en que los alumnos desde la acción y reflexión construyen sus propios conocimientos mediante este tipo de enfoque. También interesó reconocer aspectos favorables y desfavorables de la experiencia. La teoría de referencia se delimitó desde cuatro perspectivas: histórica, educativa, matemática y curricular, que a su vez sirvieron de sostén metodológico. Se analizó la información recabada de observaciones de clases, de producciones de los estudiantes y de registros del docente. Los hallazgos parecen indicar que aprender los números irracionales a través de un enfoque histórico contribuye a los aprendizajes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240769,"idioma_id":5,"titulo":"Obstáculos didácticos al trabajar con números racionales positivos al inicio de la escolaridad secundaria","resumen":"En la presente investigación se analizan los obstáculos didácticos emergentes en las clases de un primer año de escuela secundaria en Argentina cuando se trabaja con números racionales positivos. Los obstáculos didácticos engloban aquellas decisiones desacertadas por parte del profesor en situación de enseñanza. A través de un estudio cualitativo, con alcance descriptivo y particularmente mediante el análisis de contenido, fue posible reconocer 12 tipos de obstáculos didácticos. Se los caracteriza mediante una denominación y la familia de situaciones (palabras o acciones) observadas que les dieron origen. Para finalizar se realizan algunas recomendaciones para continuar el trabajo a nivel formación inicial y continua de profesores.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240771,"idioma_id":5,"titulo":"Representaciones y prácticas de profesionales de la guardia de un hospital pediátrico de la ciudad de Buenos Aires","resumen":"RESUMEN. INTRODUCCIÓN: La sanción de la Ley Nacional deSalud Mental N° 26.657 (2010) dio inicio a un proceso de reformaen la atención de personas con padecimiento mental. Los hospitalespsiquiátricos deben sustituirse por servicios comunitarios, y lasinternaciones por Salud Mental se harán sólo en hospitales generales.Para niños, niñas y adolescentes existe en la ciudad de BuenosAires un solo hospital pediátrico, que interna en salas generalesa través de una admisión por Guardia. OBJETIVOS: Describirrepresentaciones y prácticas de profesionales de guardia del citadohospital vinculadas a la atención de niños, niñas y adolescentesde 0 a 18 años de edad con padecimiento mental, identificandomodificaciones a partir de la Ley. MÉTODOS: Se efectuó un estudioexploratorio descriptivo de corte retrospectivo. Se utilizaron, comotécnicas cualitativas, entrevistas semiestructuradas a profesionales dediferentes disciplinas (Enfermería, Pediatría, Psicología, Psiquiatría,Trabajo Social y Toxicología) efectuadas en 2014-2015. Se realizó unanálisis de contenido. RESULTADOS: Según los profesionales, susprácticas concuerdan con el paradigma de la Ley, y los obstáculosen la atención e implementación se deben a insuficiencias en losrecursos intra y extrahospitalarios, en especial en las internacionesen salas generales. CONCLUSIONES: La transformación de prácticassegún la Ley debe ser acompañada de la participación de distintosactores sociales y de políticas públicas en Salud Mental.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240772,"idioma_id":4,"titulo":"VOLATILE ORGANIC COMPOUNDS FROM THE INTERACTION BETWEEN FUSARIUM VERTICILLIOIDES AND MAIZE KERNELS AS A NATURAL REPELLENTS OF SITOPHILUS ZEAMAIS","resumen":"Maize kernels are exposed to Sitophilus zeamais attack and Fusarium verticillioides infestation during storage, which can result in product deterioration and economic losses. The objective of this study was to evaluate the involvement of the Volatile Organic Compounds (VOCs) emitted by the fungi-corn system in grain-insect interactions. Volatiles emitted by healthy maize kernels were different from those emitted by fungal infected kernels, with the latter being enriched by alcohols, ketones and sesquiterpenes, which were considered early indicators of fungal contamination. The results demonstrated that the kernels exposed to the fungal VOCs and their pure compounds (1-octen-3-ol and 3-octanol) were less attractive and less damaged by S. zeamais than controls. In addition to compound adsorption, other processes may have caused the protective effect of exposed kernels against insect damage. This is the first contribution of the role of the fungal volatiles on the behavior of S. zeamais, and could provide an important contribution to the conservation of stored grains and pest management and an early indicator of fungal contamination.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240773,"idioma_id":4,"titulo":"First report of winter survival of Phakopsora pachyrhizi on kudzu (Pueraria lobata), in the province of Buenos Aires, Argentina.","resumen":"sian soybean rust (ASR), caused by Phakopsora pachyrhizi, was reported in 2002 in Argentina (Rossi, 2003). In Argentina, molecular diagnose performed with PCR technique confirmed the presence of P. pachyrhizi, not only on soybean but also on several alternative hosts like Cajan (Cajanus cajan), Kudzu (Pueraria lobata) and Mucuna (Mucuna cochinchinesis) (Ivancovich, 2005). The presence of ASR in the main soybean area of the central region (provinces of Buenos Aires, Córdoba, Santa Fe and Entre Ríos) mainly depends on the arrivals of rust spores coming from northern region of Argentina and from Brazil, Paraguay and Uruguay. Weather conditions in Argentina generally do not allow the survival of ASR neither on soybean nor on alternative host, since usually they do not survive to the winter. Kudzu is the main alternative host of ASR being very susceptible to it. Kudzu was reported in Cerro Azul (province of Misiones) and in Pergamino and La Plata (province of Buenos Aires), where ASR on kudzu it is commonly observed. Until now the ASR had never survived on kudzu in the province of Buenos Aires, however recently (September 13rd. 2017) ASR was found on kudzu in La Plata. Diagnosis of Phakopsora pachyrhizi was done under stereo microscope and optic microscope in the laboratories of the UNNOBA. The implication of this event must be studied in order to determine its possible effect on the cycle of ASR in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240774,"idioma_id":4,"titulo":"Effects of different sucrose concentrations on vitrified porcine preantral follicles: Qualitative and quantitative analysis","resumen":"The aim of the present study was to perform a qualitative and quantitative analysis of the effect ofdifferent sucrose concentrations combined with ethylene glycol in the preservation of vitrified porcinepreantral follicles. Fragments of ovarian cortex were vitrified in cryotubes containing 200 ml of thevitrification solution (30% Ethylene Glycol; 20% Fetal Bovine Serum; 0 Me0.25 M e 0.75 M or 1 M sucrose)and stored in liquid nitrogen for a week. Histological analysis showed that after vitrification thenumber of normal follicles decreased compared to the fresh tissue (control). The percentage of normalprimordial follicles was sucrose dose dependent. The percentage of normal primary follicles was similarin 0 M or 0.25 M sucrose, while higher concentrations (0.75 M and 1 M) increased significantly thepercentage of abnormal follicles (p < 0.05). Morphometric analysis showed a statistically significantreduction in the total area of primordial follicles with 0.75 M sucrose and a significant increase in thecytoplasmic area of primordial follicles with 0 M sucrose (p < 0.05). The qualitative and the quantitativeanalysis appear to be a complementary tool when choosing a vitrification protocol. For our cryopreservationsystem - vitrification of ovarian cortex slices in cryotubes-the best vitrification medium wasTCM 199-Hepes with 30% de ethylene glycol, 20% of Fetal Bovine Serum and 0 or 0.25 M sucrose. Thepresent study shows that the use of high sucrose concentrations in the vitrification solution has adeleterious effect on the preservation of porcine preantral follicles contained in ovarian tissue. Consequently,its use at 0.75 M or 1 M wouldn´t be recommended.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240775,"idioma_id":4,"titulo":"Relationship between morphological abnormalities in commercial bull frozen semen doses and conception rate","resumen":"Commercial doses of frozen bull semen for artificial insemination may have a certain percentage of morphological defects, despite being subject to prior selection. The aims of this study were to determine the prevalence of morphological abnormalities in commercial doses (n=55, r=2) of dairy and beef bulls, from AI centers and to determine the possible existence of differences between them, regarding the percentage of abnormal sperm. At least 200 sperm per sample were evaluated using Bengal Rose stain (3 % m\/v) and light microscopy (X 1000 magnification). The mean percentage of abnormal sperm samples from dairy breeds was 7.19% ± 4.91% and from beef breeds was 15.83% ± 9.28%. Significant differences between biotypes were found in the proportion of abnormal sperm, abnormal heads and abnormal midpieces; it could be due to different selection pressure. It was observed that the percentage of abnormal sperm was not a good fertility level predictor for the commercial samples of frozen bovine semen used in this study. In both biotypes, the midpiece abnormalities were the most frequent, mainly its distal flexion (compensable defect). This could be as a result of the effects of freezing and thawing on sperm.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240778,"idioma_id":5,"titulo":"La democracia venezolana en su laberinto: Cuatro caminos en búsqueda de una salida","resumen":"El artículo examina el estado actual de la crisis institucional por la que atraviesa la democracia en Venezuela y releva las posiciones asumidas por la Organización de Estados Americanos y de buena parte de los países latinoamericanos. Finalmente, presenta un ejercicio de reflexión sobre cuatro soluciones plausibles que podrían contribuir para que la democracia venezolana encuentre una salida a su laberinto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240779,"idioma_id":5,"titulo":"La dimensión política de los vínculos Argentina-Chile y Argentina-Venezuela en el inicio del Siglo XXI","resumen":"El objetivo del artículo es analizar comparativamente las relaciones Argentina-Chile y Argentina-Venezuela en el período 2003-2011, identificando sus principales similitudes y diferencias en la dimensión política, marco amplio en el que se asienta una relación bilateral. En nuestro estudio, es el estado de cosas, discursos y acciones de los gobiernos en la dimensión político-diplomática tales como los principios y mecanismos institucionales que estructuran el diálogo en las diversas issue areas. Asimismo, se busca identificar cuáles son los rasgos propios de cada vínculo y las características que comparten para sobre esa base, analizar si reúnen las condiciones para ser catalogados como alianzas estratégicas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240780,"idioma_id":5,"titulo":"Contexto contiguo y operaciones de mantenimiento de la paz en las agendas de Argentina, Chile y Venezuela en la primera década del siglo XXI: ¿espacios de complementariedad para la conformación de ambas alianzas estratégicas?","resumen":"El objetivo principal de este artículo es examinar la relevancia del contexto contiguo y de la visión y participación en Operaciones de Mantenimiento de la Paz en las agendas externas de Argentina, Chile y Venezuela en la primera década del siglo XXI. Para ello se seleccionaron las categorías de percepciones de amenaza y conflictos territoriales, gastos militares, posiciones asumidas sobre medidas de confianza mutua y participación en misiones de paz. Se parte del supuesto que los gobiernos pueden anunciar la conformación de una alianza estratégica. Ahora bien, cabe preguntar si el anuncio es una condición necesaria y suficiente de la existencia de esta forma peculiar de relación entre Estados. Se espera que este estudio permita identificar la relevancia y la existencia o no, de espacios de complementariedad en esta issue area para reflexionar acerca de cuán próximos se encuentran Argentina-Chile y Argentina-Venezuela de la conformación de una alianza estratégica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240781,"idioma_id":5,"titulo":"La vinculación entre el modelo de desarrollo y estrategia de inserción en la Argentina democrática (1983-2011)","resumen":"La relación entre el modelo de desarrollo y la estrategia de inserción internacional constituye un vínculo clave para la comprensión de la política exterior. Sin embargo, la misma ha sido poco considerada en los análisis de las relaciones internacionales contemporáneas. En este artículo nos proponemos analizar la definición de ambos conceptos, buscando identificar los canales a través de los cuales se articulan e impactan en la política externa. El artículo realiza un análisis bibliográfico y documental, donde la discusión teórico conceptual que vincula  modelo de desarrollo-estrategia de inserción se acompaña del análisis de datos empíricos correspondientes a la política exterior argentina en el período 1983-2011.*** El orden de los autores es meramente por cuestiones alfabéticas ***","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240783,"idioma_id":4,"titulo":"Development of subcutaneous fat in Spanish and Latin American children and adolescents: Reference values for biceps, triceps, subscapular and suprailiac skinfolds","resumen":"Subcutaneous fat skinfolds represent a reliable assessment instrument of adiposity status. This study provides current percentile references for four subcutaneous skinfolds (biceps, triceps, subscapular, suprailiac) applicable to children and adolescents in Spain and in Latin American countries where data are scarce.The design consisted of a cross-sectional multicenter study performed with identical methods in 5 countries (Argentina, Cuba, Mexico, Spain and Venezuela). Total sample comprised 9163 children and youths (boys 4615 - girls 4548) aged 6?18 years, healthy and without apparent pathologies. Percentiles 3, 5, 10, 25, 50, 75, 90, 95 and 97 were calculated by the LMS method. Sexual dimorphism was assessed using the t-test and age differences with ANOVA. Normalized growth percentile references were obtained according to sex and age for each skinfold. The mean values of four skinfolds were significantly greater in girls than boys (p < 0.001) and, in both sexes, all skinfolds show statistical differences through age (p < 0.001) with different magnitudes.Except triceps in girls, peaks between 11 and 12 years of age are more noticeable in boys than in girls. Although the general model of growth is known, the skinfold measurements show variability among populations and differences of magnitude are presented according to the analyzed population. Therefore, these age and sex-specific reference percentile values for biceps, triceps, subscapular and suprailiac skinfolds, derived from a large sample of Spanish and Latin American children and adolescents, are a useful tool for adiposity diagnosis in this population for which no reference values were available.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240784,"idioma_id":4,"titulo":"An intact acrosome is required for the chemotactic response to progesterone in mouse spermatozoa","resumen":"Mammalian sperm become fertilization-competent in the oviduct, during a process known as capacitation that involves the acquisition of the ability to exocytose the acrosome but also the chemotactic responses ? both of which contribute to successful fertilization. Chemotaxis is used by spermatozoa to orient and to locate the egg; the acrosome reaction facilitates sperm binding to and fusing with the egg membrane. Mammalian spermatozoa are able to sense picomolar concentrations of progesterone, which drives chemotactic behavior. The state of the acrosome during the chemotactic response, however, is unknown. Genetically modified mouse spermatozoa were employed in a chemotaxis assay under fluorescence microscopy to evaluate the acrosome status while swimming, allowing us to elucidate the acrosome integrity of sperm responding to progesterone-induced chemotaxis. We first showed that wild-type mouse spermatozoa chemotactically respond to a gradient of progesterone, and that the genetic modifications employed do not affect the chemotactic behavior of sperm to progesterone. Next, we found that acrosome-intact, but not acrosome-reacted, spermatozoa orient and respond to picomolar concentrations of progesterone and that chemotaxis normally occurs prior to the acrosome reaction. Our results suggest that premature commitment to acrosome exocytosis leads to navigation failure, so proper control and timing of the acrosome reaction is required for fertilization success and male fertility. This article is protected by copyright. All rights reserved","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240785,"idioma_id":4,"titulo":"Sperm chemorepulsion, a supplementary mechanism to regulate fertilization","resumen":"STUDY QUESTION Are human spermatozoa able of chemorepulsive behaviour? SUMMARY ANSWER Capacitated human spermatozoa are able to be chemorepelled by synthetic Progesterone Receptor Ligands (sPRL, known as contraceptives) and zinc (a cation released by the oocyte upon fertilization). WHAT IS KNOWN ALREADY Moving cells can be oriented towards or against a molecular gradient, processes called chemoattraction and chemorepulsion, respectively, which have been described in unicellular organisms such as amoebas and bacteria, to organismic cells such macrophages and developmental cells. In the case of spermatozoa, chemoattraction may help the finding of an oocyte and has been widely studied in various invertebrate and mammalian species; however, chemorepulsion has not yet been verified in spermatozoa. STUDY DESIGN, SIZE, DURATION This is an in vitro study involving human, rabbit and mouse spermatozoa which were used to perform 3-30 experiments per treatment. PARTICIPANTS\/MATERIALS, SETTING, METHODS Human sperm samples were obtained by masturbation from healthy donors who gave written consent. Only those samples exhibiting normal semen parameters according to current WHO criteria were included in the study. Rabbit spermatozoa were obtained by artificial vagina whereas mice spermatozoa were obtained from epididymis. The sperm selection assay (SSA), originally designed to evaluate sperm chemoattraction towards progesterone (P), and a video-microscopy and computer motion analysis system were used to test sperm chemorepulsion. Additional kinetic parameters were also determined by video-microscopy and computer motion analysis. In some experiments, the level of induced acrosome-reacted spermatozoa was determined. Rabbit mating manipulation was achieved to perform the sperm-oocyte co-incubation assay. MAIN RESULTS AND THE ROLE OF CHANCE Sperm accumulation in the well containing 100 pg\/ml of sPRL was lower than the culture medium negative control (P < 0.05). The percentage of sperm persistence against the well containing 100 pg\/ml ulipristal acetate (UPA) (P = 0.001), and the percentage of sperm showing a repulsive pattern of movement (a linear trajectory followed by a transitional one after turning against the UPA), were higher than the culture medium negative control (P = 0.049). Sperm accumulation was diminished when spermatozoa where exposed to a homogeneous distribution of 100 pg\/ml sPRL combined with a chemotactic gradient of progesterone (P), with respect to the culture medium negative control (P < 0.05). These results were reverted when non-capacitated spermatozoa were used to perform the same experimental settings. The accumulation of spermatozoa against 100 pg\/ml sPRL was lower than the culture medium negative control also in rabbits and mice (P < 0.05). The relative number of rabbit spermatozoa arriving to the vicinity of the oocyte was diminished under the presence of 100 pg\/ml UPA (P = 0.004). Sperm accumulation in the well containing zinc was decreased compared to the culture medium negative control (P < 0.05). A homogeneous distribution of zinc combined with a gradient of 10 pM P, was lower than the culture medium negative control (P = 0.016). The results were quite reproducible with two different methodologies (accumulation assay and video-microscopy combined with computer motion analysis), in three mammalian species. LIMITATIONS REASONS FOR CAUTION The experiments were performed in vitro. Even though a quite complete characterization of sperm chemorepulsion was provided, the molecular mechanism that governs sperm repulsion is currently under investigation. WIDER IMPLICATIONS OF THE FINDINGS Since the chemorepelled spermatozoa are those physiologically ready to fertilize the oocyte, these findings may have both biological and clinical implications, preventing either polyspermy under natural conditions or fertilization under pharmacological treatment with sPRL. STUDY FUNDING\/COMPETING INTEREST(S) The study was financed by the Universidad Nacional de Cordoba (Argentina). The authors declare that they do not have competing financial interests. TRIAL REGISTRATION NUMBER N\/A.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240786,"idioma_id":4,"titulo":"Comparative sperm ultrastructure of two tegu lizards (genus Salvator) and its relation to sperm competition","resumen":"The knowledge of sperm ultrastructure of Squamata provides informative traits for phylogenetic analyses. Furthermore, several sperm ultrastructure traits are important for sperm motility and longevity. Here, we provided a detailed ultrastructural description of the spermatozoa of two closely related teiid lizards, Salvator rufescens and S. merianae. We carried out an interspecific comparison of sperm ultrastructure traits and discussed their possible relation to sperm competition risk. Sperm ultrastructure of the two species shared patterns with other lizards previously described. The lack of interspecific differences in most sperm subcellular components, suggested that sperm ultrastructure traits are conserved within the genus Salvator and thus pointed out an important phylogenetic influence. However, we detected interspecific differences in the number of mitochondria and dense bodies sets, suggesting differences in the amount of energy available for sperm motility and longevity. Further comparative studies are urgently needed to understand the sperm metabolic pathways in neotropical lizards in general.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240787,"idioma_id":5,"titulo":"COMPORTAMIENTO ALIMENTARIO Y ESTADO NUTRICIONAL EN NIÑOS DE LA CIUDAD DE PERICO ? JUJUY","resumen":"Los estilos de vida saludables se basan en patrones de comportamientos, determinados por la interacción entre las características individuales, sociales, culturales y las condiciones socioeconómicas. La alimentación implica una dimensión sociocultural más amplia que afecta a los estilos de vida, por eso el consumo de alimentos está relacionado con o por las pautas culturales construidas por los actores en cada sociedad. Se evaluó el estado nutricional de una población escolar y se relacionó el mismo a sus hábitos alimentarios como reflejo de su estilo de vida. Se analizaron 466 registros de niños de 5 a12 años de ambos sexos que asisten a un establecimiento educativo público de nivel primario. Se registró peso (kg) y talla (cm) y se calculó el Índice de Masa Corporal (IMC) por edad y sexo. Mediante una encuesta se relevaron datos de hábitos y alimentos ingeridos. Se observó que el 70% se encuentra dentro de un estado nutricional normal, un 6% de delgadez y un 24 % de exceso de adiposidad. Los hábitos alimentarios muestran que el 43% no desayuna; el 72% consumen algún alimento o bebida en el recreo, un 70,2% mira TV más de dos horas.Se concluye que estamos en presencia de una prevalencia negativa de la salud, en la cual la presencia del sedentarismo se relaciona con factores sociales, culturales, con la ausencia de actividad física y de hábitos alimentarios adecuados. Dado que las prácticas culturales tienen marcada incidencia en los patrones alimentarios de esta comunidad, la cual es reflejo de sus estilos de vida.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240789,"idioma_id":5,"titulo":"Educación Intercultural Bilingüe: El otro en la diversidad","resumen":"El término ?diversidad? para designar la alteridad cultural fue utilizado por la teoría evolucionista, constitutiva de las ciencias antropológicas a fines del siglo XIX, como sinónimo de ?diferencia? (Boivin et al., 1998). Pero ello fue cambiando, ya que durante el lapso que va desde las dos guerras mundiales, las escuelas antropológicas comienzan a utilizar el término diversidad de manera sistemática y sustitutiva al de diferencia. Es aquí donde nos posicionaremos durante el desarrollo del presente ensayo: desde la alteridad como sinónimo de diversidad.Para ver y comprender el modo en que se construyó la otredad a partir de la diversidad, tomaremos aportes de la teoría estructuralista de Levi Strauss, específicamente el concepto de etnocentrismo","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240792,"idioma_id":5,"titulo":"Discursos culturales en torno a las maternidades. Sus tensiones.","resumen":"El presente trabajo es parte del Proyecto de Investigación cuatrienal (2016-2020) titulado ?Lo femenino y lo maternal en nuestra época?. En esta oportunidad presentamos los modos actuales que predominan en la cultura para ?decir? las maternidades. Retomamos la diferencia que planteamos en trabajos anteriores, entre experticia y experiencia, para sumarle a los primeros, pertenecientes a la divulgación científica, los discursos de la publicidad, como su continuación;y como reverso de las postulaciones positivistas, tomamos el discurso literario conjugado en la obra de Ariana Harwicz; que apunta a la experiencia singular.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240797,"idioma_id":4,"titulo":"Inducible expression of Bs2 R gene from Capsicum chacoense in sweet orange (Citrus sinensis L. Osbeck) confers enhanced resistance to citrus canker disease","resumen":"Transgenic expression of the pepper Bs2 gene confers resistance to Xanthomonas campestris pv. vesicatoria (Xcv) pathogenic strains which contain the avrBs2 avirulence gene in susceptible pepper and tomato varieties. The avrBs2 gene is highly conserved among members of the Xanthomonas genus, and the avrBs2 of Xcv shares 96% homology with the avrBs2 of Xanthomonas citri subsp. citri (Xcc), the causal agent of citrus canker disease. A previous study showed that the transient expression of pepper Bs2 in lemon leaves reduced canker formation and induced plant defence mechanisms. In this work, the effect of the stable expression of Bs2 gene on citrus canker resistance was evaluated in transgenic plants of Citrus sinensis cv. Pineapple. Interestingly, Agrobacterium-mediated transformation of epicotyls was unsuccessful when a constitutive promoter (2× CaMV 35S) was used in the plasmid construction, but seven transgenic lines were obtained with a genetic construction harbouring Bs2 under the control of a pathogen-inducible promoter, from glutathione S-transferase gene from potato. A reduction of disease symptoms of up to 70% was observed in transgenic lines expressing Bs2 with respect to non-transformed control plants. This reduction was directly dependent on the Xcc avrBs2 gene since no effect was observed when a mutant strain of Xcc with a disruption in avrBs2 gene was used for inoculations. Additionally, a canker symptom reduction was correlated with levels of the Bs2 expression in transgenic plants, as assessed by real-time qPCR, and accompanied by the production of reactive oxygen species. These results indicate that the pepper Bs2 resistance gene is also functional in a family other than the Solanaceae, and could be considered for canker control.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240798,"idioma_id":4,"titulo":"Relationships between copper content in orange leaves, bacterial biofilm formation and citrus  canker disease control after different copper treatments","resumen":"Citrus canker is caused by Xanthomonas citri subsp. citri (X. citri), a severe and wide-spread bacterial pathogen. Repeated copper sprays are part of integrated management systems applied in countries where canker is endemic. The objective of this research was to evaluate the effect of a low copper compound, copper sulphate pentahydrate, as soil applications and sprays on canker intensity, in comparison with traditional application of copper oxychloride. Two independent trials were conducted in 2010 and 2011 in a canker endemic sweet orange orchard. Products were monthly applied during springs.Copper content in young leaves and fruits after each application was assessed through an atomic absorption spectrometer.In addition, the ability of treatments to interfere with bacterial biofilm formation was evaluated under controlled conditions.Soil application of copper sulphate pentahydrate did not reduce citrus canker incidence. In 2011, the pulverization of copper sulphate pentahydrate and copper oxychloride reduced the incidence of the disease compared with untreated trees. Notably, copper content in leaves sprayed with the first compound was significantly lower than in leaves treated with copper oxychloride. However, both treatments showed the same ability to avoid biofilm formation, the first step in establishment of canker disease. Consequently, the pulverization of copper sulphate pentahydrate, integrated with the monitoring of the phenological tree stages and the weather conditions, could constitute a useful tool for the management of citrus canker disease, of high importance to avoid the adverse environmental effects, the risk of phytotoxicity, and the development of copper resistant bacterial populations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240801,"idioma_id":5,"titulo":"METODOLOGIAS DE INVESTIGACION DE LOS CUATRO ASPECTOS DE BASE DEL MARKETING ESENCIAL","resumen":"ResumenExiste mucha literatura del marketing acerca de las metodologías de investigación sobre los aspectos operativos y tácticos del marketing tradicional. Ahora, toda ella se refiere a las consecuencias de aplicar un plan de marketing, pero nada se dice acerca de cómo se interpretan las causas esenciales que movilizan el consumo que como es de prever deben ser la base estratégica del proceso de toma decisiones del plan marketing, ya sea doméstico o internacional. Este documento analiza esta problemática y presenta las metodologías de investigación para cada uno de los cuatro aspectos esenciales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240802,"idioma_id":4,"titulo":"Zonal Selectivity by Sensitivity Modulation in Linear Tetrapolar Impedance Sensors","resumen":"This work investigates the behaviour of a tetrapolar impedance sensor due to sensitivity issues caused by inherent method measurement when inter-electrode spacing is changed. Finite Element Method (FEM) modelling of the sensitivity spectra was computed to analyse maximum sensitivity levels in desired zones of the sample and non-common known and unintuitive phenomenon as negative sensitivity lobes inside the sensitivity distribution field. Sensitivity maps as a function of electrode position were obtained and maximum sensitivity curves were extracted to identify the best configuration for major sensitivity contribution to characterize a specific sample section.A prototype of a linear tetrapolar sensor array of planar microelectrodes for sensing ionic samples was used for the computational modelling and a brief experimental validation was performed to show the vertical stratification process. The analysis shows that it is possible to have zonal selectivity in the impedance measurement and characterize a desired zone of the sample modulating the sensitivity, changing the electrode position by a scale pattern. This manuscript offers a novel approach for designing tetrapolar sensors based on analyzing maximum sensitivity curves obtained by FEM modelling.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240806,"idioma_id":4,"titulo":"Life cycle and host specificity of the parasitoid Conura annulifera (Hymenoptera: Chalcididae), a potential biological control agent of Philornis downsi (Diptera: Muscidae) in the Galápagos Islands","resumen":"The neotropical parasitoid Conura annulifera (Walker) (Hymenoptera: Chalcididae) is known to parasitize bird-parasitic flies in the genus Philornis (Diptera: Muscidae) including P. downsi (Dodge and Aitken), a species that has invaded the Galápagos islands and is negatively impacting populations of Darwin?s finches. We report here some aspects of the life history, field ecology, and host specificity of C. annulifera. We collected puparia of four Philornis species in 13 bird nests during 2015 and 2016 in western mainland Ecuador and found that C. annulifera and three other parasitoid species emerged from those puparia. This is the first record of C. annulifera in Ecuador. Rearing records and dissections of parasitized puparia revealed that C. annulifera is a solitary pupal ectoparasitoid, placing its eggs in the gap between host pupa and puparium. Laboratory studies of host specificity involving P. downsi and pupae from five other dipteran, three lepidopteran, and one hymenopteran species found that C. annulifera only produced progeny when presented with P. downsi pupae. Pupae of P. downsi that had been exposed to C. annulifera also failed to emerge more often than expected by chance compared with no-parasitoid controls, suggesting that the parasitoids can cause developmental mortality through means other than successful parasitism. These studies constitute the first steps in evaluating C. annulifera as a potential biological control agent of P. downsi in the Galápagos Islands.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240807,"idioma_id":4,"titulo":"Coextinction dilemma in the Galápagos Islands: Can Darwin?s finches and their native ectoparasites survive the control of the introduced fly Philornis downsi?","resumen":"1. The survival of parasites is threatened directly by environmental alteration and indirectly by all the threats acting upon their hosts, facing coextinction.2. The fate of Darwin´s finches and their native ectoparasites in the Galápagos Islands is uncertain because of an introduced avian parasitic fly, Philornis downsi, which could potentially drive them to extinction.3. We documented all known native ectoparasites of Darwin´s finches. Thirteen species have been found: nine feather mites, three feather lice and one nest mite. No ticks or fleas have been recorded from them yet.4. Management options being considered to control P. downsi include the use of the insecticide permethrin in bird nests which would not only kill the invasive fly larvae but the birds? native ectoparasites too.5. Parasites should be targeted for conservation in a manner equal to that of their hosts. We recommend steps to consider if permethrin-treated cotton stations are to be deployed in the Galápagos archipelago to manage P. downsi.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240808,"idioma_id":4,"titulo":"Isolation and Characterization of Microsatellite Loci from Arthropodium cirratum (Asparagaceae)","resumen":"Premise of the study: Microsatellite markers were developed for Arthropodium cirratum (Asparagaceae) to study population genetic structure and translocation of this species. These markers were tested for cross-amplification in two other Arthropodium species. Methods and Results: Sixteen microsatellite markers were developed from a genomic library and tested in three populations of A. cirratum. The loci exhibited one to five alleles per locus, with private alleles present in each of the populations. Cross-amplification tests in the two other New Zealand Arthropodium species revealed that many of the loci amplify and demonstrate polymorphism in A. bifurcatum. Conclusions: These markers will be useful for determining genetic structure in Arthropodium cirratum and for determining the origins of translocated populations of this species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240812,"idioma_id":5,"titulo":"Laboratorio portátil de escritorio para la enseñanza de la electrónica","resumen":"La forma de impartir enseñanza debe cambiar para satisfacer a la nueva generación de estudiantes que quiere aprender por vías no tradicionales y empleando nuevas tecnologías.Los estudiantes de esta generación se consideran dueños de las Tecnologías deInformación y Comunicación (TICs), poseen una asombrosa capacidad de adaptación en toda actividad que las implique, y ostentan un nivel de decodificación visual o iconográfica mayor que las generaciones anteriores, por lo que a veces rechazan los modos tradicionales de exposición En este trabajo se presentauna propuesta de estrategia metodológica basada en el aprendizaje experiencial de Kolb para ser aplicado a la enseñanza de la Electrónica Básica mediante la implementación de laboratorios portátiles de escritorio en diferentes asignaturas de la carrera Ingeniería en Electrónica (UNCa).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240813,"idioma_id":4,"titulo":"Development and evaluation of an automatic software for management zone delineation","resumen":"The lack of availability of user-friendly and automatic software for managementzone delineation is limiting the adoption of site-specific management practices. Several procedures for management zone delineation have been proposed, but they commonly require the use of different software, or advanced GIS and statistical skills of users, which limit their adoption. This study proposes a user-friendly and automatic software that would integrate all steps in order to delineate management zones and make prescription files. The software includes importation of different input data layers, re-projection and resizing data in a common grid size. An integrative index was proposed for the selection of the optimal number of zones after clustering analysis. Users are guided by graphical windows showing intermediate results. Also, additional automatic post-processing techniques to improve size, shape and fragmentation of delineated zones are  vailable. The final step allows generation of the ESRI Shapefile required to make variable rate prescriptions by zone with minimal user intervention. The performance of the approach was evaluated for management zone delineation using single and multiple layers of data by comparing with Management Zone Analyst software, and the improvement of the approach in the selection of the optimal number of zones and reducing zone-fragmentation was shown. The software design includes a simple graphical user interface and requires minimal user intervention in order to assist the end-user. The main contribution of this work was the successful development of this automatic user-friendly solution that includes all the necessary steps for management zone delineation and prescription file generation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240814,"idioma_id":5,"titulo":"Obtención y caracterización de depósitos de poliéterétercetona (PEEK) y chitosán mediante deposición electroforética con corriente alterna","resumen":"En este trabajo se presenta un estudio comparativo de la deposición electroforética de los biopolímeros chi-tosán y poliéterétercetona (PEEK) utilizados en biomedicina, usando campos eléctricos de corriente alterna con frecuencias bajas (0,01 hasta 1000 Hz) llamado electroforesis de CA de baja frecuencia (ACEPD). La técnica utilizada es la deposición electroforética (EPD), la cual posee una extensa variedad de aplicaciones en el área de recubrimientos debido a la facilidad de su empleo y bajo costo. En la técnica de AC-EPD, la dirección del campo eléctrico se invierte periódicamente dependiendo de la frecuencia y asimetría de la on-da aplicada. Esto explica la oscilación y la migración de partículas contenidas en la suspensión. Esta migra-ción oscilante generó que las partículas se depositaron en ambos electrodos y el recubrimiento creció desde la periferia hacia el centro de los electrodos hasta cubrir totalmente el sustrato metálico. Se realizaron estu-dios experimentales para optimizar la calidad de las películas depositadas por EPD, desde el punto de vista de la densidad y adherencia de los depósitos al sustrato, que incluyen la evaluación de diversos parámetros tales como tiempo de deposición, voltaje aplicado, pH, etc. La caracterización microestructural de las pelí-culas obtenidas, tanto en verde como sinterizadas fue realizada por microscopía óptica y microscopía elec-trónica de barrido (MEB) corroborando de este modo, la obtención de recubrimientos funcionales con la microestructura buscada. Los recubrimientos obtenidos por AC-EPD de chitosán fueron homogéneos, den-sos y uniformes. Los depósitos de PEEK no tuvieron la homogeneidad y adherencia buscada debido a la naturaleza de la suspensión utilizada en el proceso.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240815,"idioma_id":4,"titulo":"Hypercyclic behaviour of some non-convolution operators on $H(C^N)$","resumen":"We study hypercyclicity properties of a family of non-convolutionoperators defined on spaces of holomorphic functions on $C^N$. These operators are a composition of a differentiation operator and an affine composition operator, and are analogues of operators studied by Aron and Markose on $H(C)$. The hypercyclic behavior is more involved than in the one dimensional case, and depends on several parameters involved.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240817,"idioma_id":5,"titulo":"Correlación de propiedades mecánicas y comportamiento tribológico de recubrimientos de Poliéterétercetona (PEEK) obtenidos por deposición electroforética","resumen":"Poliéterétercetona (PEEK) es un polímero orgánico termoplástico semicristalino, incoloro, que ofrece una combinación única de altas propiedades mecánicas, resistencia a la temperatura y excelente resistencia química [1-3]. Por el conjunto de sus características distintivas es un material adecuado para aplicaciones que requieren altas prestaciones mecánicas bajo condiciones extremas de temperatura, agresividad química o alta energía radiante. Consecuentemente es empleado en todas las industrias en general, y en aplicaciones de alta tecnología tales como la ingeniería de tejidos [3]. En este estudio se han depositado revestimientos de poliéterétercetona (PEEK) sobre sustratos de acero inoxidable 316L, a través de la técnica de deposición electroforética (EPD), atractiva debido a su bajo costo y sencillez operativa [4,5]. Como baño electroquími-co se desarrollaron suspensiones etanólicas conteniendo partículas micrométricas de PEEK [6]. El rendimien-to de la EPD aumentó con el tiempo de deposición y la diferencia de potencial aplicada, y se obtuvieron depósitos uniformes del polímero sobre el sustrato a los cuales se aplicó un tratamiento térmico a 343 °C durante 30 min con una velocidad de calentamiento 10 °C min-1 para aumentar la adhesión entre el sustrato y el recubrimiento. Para estudiar el comportamiento de las películas obtenidas se investigaron las propiedad-es: resistencia a la compresión, resistencia a la fractura, módulo de elasticidad, dureza, espesor de los recu-brimientos, coeficiente de fricción y rugosidad. Es importante entender cómo las propiedades mecánicas del PEEK afectan su comportamiento tribológico [7]. La microestructura de las películas superficiales y su composición se investigó mediante un microscopio electrónico de barrido (SEM) JEOL JSM-7000F equipado con espectroscopía de energía dispersiva (EDS). Los resultados obtenidos permiten concluir que la técnica de deposición electroforética es adecuada para la obtención de recubrimientos mediante el empleo de biopolí-meros, y además permite la producción de películas de distinto espesor lo suficientemente resistentes como para ser empleadas en biomedicina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240819,"idioma_id":5,"titulo":"Informe sobre el uso de los recursos de internet en el sector servicios de la ciudad de Mar del Plata.","resumen":"En el año 2014 se aprobó en la Universidad Nacional de Mar del Plata el primer proyecto de investigación en el marco del Grupo Tercer Sector orientado a brindar información sobre el acceso y uso de las TIC -tecnologías de la información y de la comunicación- en el Partido de General Pueyrredon. Del trabajo desarrollado en éste proyecto y en el siguiente aprobado en el año 2016 surge la propuesta de elaborar una publicación con periodicidad anual para facilitar la toma de decisiones sobre el empleo de tecnologías para la comunicación con los públicos de interés bajo el nombre Informe sobre el uso de los recursos de internet en el sector servicios de la ciudad de Mar del Plata.  El equipo de trabajo se constituye por investigadores formados en diferentes disciplinas (Administración, Contable, Estadística y Tecnologías) favoreciendo así un abordaje plural para el análisis de la brecha digital y su relevancia ya sea como ventaja competitiva para las organizaciones o como factor diferencial en el empoderamiento de los usuarios. Esta situación ha permitido además estudiar la comunicación a través de internet desde diferentes teorías extendiendo en la actualidad la propuesta de investigación hacia la responsabilidad social y el desarrollo sustentable. En el relevamiento de datos colaboraron los estudiantes avanzados de la carrera de Contador Público en el cumplimiento del requisito curricular Horas de Investigación.Esta publicación tiene como propósito ofrecer a la comunidad información estadística que permita conocer los diferentes grados de avance logrados en el empleo de las TIC, es decir sobre quiénes usan las herramientas así como cuáles se emplean. Si bien los estudios han tenido en sus inicios a las organizaciones asociativas como principales destinatarias, en la actualidad se ofrece una visión abarcativa del sector de actividad económica en el que se encuentran insertas a fin de aportar información de contexto necesaria para establecer las distancias y desigualdades entre ellas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240821,"idioma_id":5,"titulo":"Decisiones judiciales y conflictos morales. Un análisis desde la virtue jurisprudence","resumen":"A partir de la disyuntiva que enfrentan los jueces entre aplicar una norma jurídica, o no ha-cerlo por considerarla injusta en el caso ?Almendras, José Alberto s\/ Delito c\/ Las perso-nas?, se intentará presentar el problema de los dilemas morales en la argumentación judi-cial y su correspondencia con la ética judicial. Para ello, se comenzará proponiendo una clara distinción entre casos fáciles, difíciles y dilemas morales. Luego se presentará breve-mente el caso, para, finalmente intentar ofrecer algunas reflexiones finales a la luz de la vir-tue jurisprudence. La conclusión será que la virtue jurisprudence, permite analizar la Justi-cia de una norma en un caso concreto, a la luz de las exigencias morales, ya que al enfocar-se en el carácter del agente y proponer como criterio de evaluación de un argumento al juez virtuosos, que se desempeñará de manera moral, entonces, subsana el problema de la justi-ficación moral de la decisión jurídica","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240822,"idioma_id":5,"titulo":"Moralidad, fantasía e ideología. Algunos aportes a partir del artículo de Malem Seña ?¿Pueden las malas personas ser buenos jueces??","resumen":"En un trabajo titulado ?¿Pueden las malas personas ser buenos jueces?? Malem Seña realiza un análisis de vida moral de los jueces. Para comenzar, a través de un análisis histórico plantea que, en un primer momento al no tener los jueces la obligación de fundamentar sus sentencias, eran ellos mismos el espejo de la legitimidad y moralidad de sus decisiones; mientras que, con el advenimiento del racionalismo y del Estado Moderno, las sentencias debían tener el fundamento acerca de por qué se decidía en ese sentido, por lo que la legitimidad o justicia de la misma estaba dada por dichas razones, situación que ponía a la persona del juez en un segundo plano. En este escenario la respuesta a la pregunta planteada en el trabajo sería: ?si, las malas personas pueden ser buenos jueces?, respuesta difícilmente aceptada por todos. Malem Seña, lejos de dar una respuesta concluyente, termina su trabajo con la insinuación que, los jueces deben mantener una imagen de moralidad, más que ser agentes moralmente intachables. Esta situación permite preguntarse sobre distintas dimensiones de análisis que se han dejado de lado, y en particular, intentar analizar por qué toma importancia la imagen de moralidad. Para ello, desde la perspectiva de los conceptos de ideología y fantasía de Slavoc ?i?ek, se intentará brindar algunas respuestas o generar caminos a fin de poder analizar la importancia de la imagen de moralidad por sobre la moralidad misma.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240823,"idioma_id":5,"titulo":"Las prácticas de enseñanza en la educación superior: un enfoque teórico-analítico (2017)","resumen":"Las prácticas de enseñanza en la educación superior: un enfoque teórico-analítico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240824,"idioma_id":4,"titulo":"Developing Research and Study Courses (RSC) in the pre-service teacher education","resumen":"In this paper, we present results of an implementation of research and study course carried out into a teacher training course in the University. The framework of the Anthropological Theory of the Didactic (ATD) is adopted, and a co-disciplinary Research and Study Path (RSP) whose generative question requires studying mathematics and physics together is carried out by training teachers of Mathematics at University. Some conclusions concerning on the conditions, restrictions and relevance of introducing the RSP in teachers training courses at the university are presented.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240825,"idioma_id":4,"titulo":"Update on the fluorometric measurement of enzymatic activities for Lysosomal Storage Disorder detection: The example of MPS VI","resumen":"Lysosomal Storage Disorders (LSD) are rare diseases that as a whole havea combined incidence ranging from 1:1500 to 1:7000 live births. One of suchdiseases is Mucopolysaccharidosis VI (MPS VI), or Maroteaux Lamy Syndrome.MPS VI patients undergo devastating and irreversible skeletal alterations andmultisystemic failure as from early childhood due to reduced Arylsulfatse B(ARSB) enzyme activity.Reaching a final diagnosis is not always a short cut path, but rather a yearslongbattle against uncertainty and unnecessary medical interventions. Ouraim is to contribute from the bench table with different approaches that couldserve as alternatives to pre-existing assays for screening and diagnosing MPSVI and other LSD.The present work is based on our research article authored by Franco etal.1 where we studied the effect of blood-derived hemoglobin, and other bloodcomponents, on the fluorescence of 4-Methylumbelliferone when measuringARSB enzyme activity from dried blood spot (DBS) samples.Our experience indicates that to date there are plenty of differentapproaches for measuring ARSB enzyme activity, although the sample typerequired or the assay in itself often make them more adaptable for either highthroughput screening or small scale diagnostics.As a whole, the fluorometric determinations seem to be the mostaccessible to low budget laboratories with equally valuable performancesas a sophisticated mass spectrometry analysis for this disease. Furthermore,the DBS serves as an attractive sample type for screening the disease in largepopulations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240826,"idioma_id":4,"titulo":"Modelling respiration rate of soybean seeds ( Glycine max (L.)) in hermetic storage","resumen":"The dynamic of oxygen (O2) and carbon dioxide (CO2) concentration was characterized in soybean (Glycine max (L.)) samples hermetically stored in glass jars at 15, 25 and 35 C and 13, 15 and 17% moisture content (m.c., wet base). Two correlations were used for smoothing gas concentration in time: linear and exponential. Then, the respiration rate at each temperature and m.c. combination was calculated as storage time progressed and oxygen was consumed and two predictive models for respiration were proposed: Model I (temperature and m.c. dependent) and Model II (temperature, m.c. and oxygen dependent). It was observed that respiration rate increased with storage m.c. and temperature. However, respiration rate was not mainly affected by O2 until a critical concentration limit of about 2% was reached. Respiration rates were from 0.341 to 22.684 mg O2\/(kgDM d) and from 0.130 to 20.272 mg CO2\/(kgDM d) for a range of storage condition of 13e17% m.c. and 15e35 C temperature. The respiration rate of soybean seeds obtained in this study resulted significantly lower than the rates reported in the literature for other grains at similar temperature and aw (water activity) storage condition. For hermetic storage simulations in which O2 concentration is not expected to drop below 2%, the simplest model (Model I) could be used, but if the O2 concentration of the hermetic system is expected to be depleted, Model I would under estimate the time at which O2 is consumed, and thus a model with O2 dependency is recommended instead (Model II).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240828,"idioma_id":5,"titulo":"Didáctica de la Biomecánica: Cimientos  para la construcción de una nueva Didáctica Específica","resumen":"Desde hace varias décadas, las Didácticas Específicas vienen realizando valiosos aportes en su relación con ciencias como la Física y la Biología, aunque no con la Biomecánica. Por ello, dado su alto grado de desarrollo actual y ante la perspectiva de un mayor crecimiento, con la consecuente necesidad de enseñarla para ser aprendida y aprehendida, en este trabajo se propone la conformación de una Didáctica de la Biomecánica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240829,"idioma_id":4,"titulo":"Bacteria and smoke-water extract improve growth and induce the synthesis of volatile defense mechanisms in Vitis vinifera L.","resumen":"Sustainable agricultural practices have been developed as alternativeto the use of agrochemicals, and viticulture is not exempt of that. Plantgrowth promoting rhizobacteria (PGPR) and smoke water extracts (SW) areenvironmentally-friendly alternative to those agrochemicals. The aim of thisstudy was to investigate the single or combined effects of SW and the PGPR Pseudomonasfluorescens (Pf) and Bacillus licheniformis (Bl) on thephysiology and biochemistry of grapevines plants. After 38 days, singleapplications of SW solutions and bacterial suspensions increase rooting androot length. Combined treatments had a slight positive effect compared to thewater control. At the end of 60-days pot trial, grapevine treated with 1:1000SW and Pf applied alone showed increases in stem length, leaf area andfresh weight of the roots, shoot and leaves, although not significantlydifferences from the water control were found. In addition, Pf augmentedchlorophyll relative content, all treatments decreased the stomatal conductance(mainly 1:500 SW, Pf and 1:1000 SW + Bl), as well as lipidperoxidation in roots (mainly in bacterial treatments), and induced thesynthesis of mono and sesquiterpenes in leaves, where the effect was enhancedin combined treatments. In conclusion, PGPR and SW are effective to improvegrowth of V. vinifera cuttings as well as to increase the plants defensemechanisms that may help them to cope with biotic and abiotic stresses.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240830,"idioma_id":4,"titulo":"Arsenic and trace elements in soil, water, grapevine and onion in J&aacute;chal, Argentina","resumen":"Contamination by trace elements (TE) is an increasing concernworldwide. In some areas, crop production could be limited by the presence of metals andmetalloids, so it is important to determine their concentrations and mobility. The region of Jáchal, province of San Juan, Argentina, has good growing conditions for onion and grapevine production, but their quality and yield are affected by high TE concentration in soils and water. Soils, water,grapevine and onion were sampled and TE content determined. In soils elevated As, B, Cr, Hg, and Tl concentrations were detected (506 ± 46, 149 ± 3, 2714 ± 217, 16 ± 7, and 12 ± 3 &#956;g g&#8722;1, respectively, for maximum values measured), and physicochemical properties of the soil promotes these elements mobility.Water samples had high As, B, Cr, and Fe concentrations (1438 ± 400, 10,871 ± 471, 11,516 ± 2363, and 3071 ± 257 &#956;g L&#8722;1,respectively, for maximum values measured) while in onion bulbs and grapevine berries, As, Cr, Cu, and Fe (92 ± 7 and 171±20, 1412±18 and 2965±32, 17 ± 3 and 126 ±88, and 418±204 and 377±213 &#956;g g&#8722;1, respectively, for maximumvaluesmeasured) exceeded the limits for food consumption established by Argentinian law. Correlation analyses indicated that: i) there is a common source of TE in this area, ii) each elements concentrationin plants is associatedwith different soil variables and different soils depths, and iii) the lack of correlation between soil and water indicates that concentration in water is not constant over the time and\/or there exists a differential accumulation of elements in soils depending on their own properties. Data obtained demonstrate very high concentration of TE in soil, grapevines, and onion plants in Jáchal region, and different remediation techniques are necessary to stabilize and minimize the bioavailability of these elements.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240831,"idioma_id":5,"titulo":"Análisis de la biodisponibilidad tisular de polifenoles totales mediante las técnicas de Folin Ciocalteu y Fast Blue BB en órganos de ratones Balb\/c","resumen":"El potencial biosanitario de los polifenoles radica en su capacidad para modular el balance redox y losmecanismos implicados en el desarrollo de enfermedades crónicas no transmisibles.Objetivo: El objetivo de este estudio fue determinar la concentración de polifenoles totales en diferentesórganos murinos mediante el ensayo de las técnicas analíticas de Folin Ciocalteu (FC) y Fast Blue BB(FBBB).Método: ratones Balb\/c hembras (n&#8805;3) recibieron durante 15 días 100 mg\/Kg\/d de extracto de Lantanagrisebachii (LG), Aspidosperma quebracho-blanco (AQB) o Ilex paraguariensis (IP) y el grupo control(tratados con agua sin extracto). Las concentraciones de polifenoles se midieron en telencéfalo, diencéfalo,mesencéfalo, tallo encefálico, cerebelo, bazo, timo y tejido cardiopulmonar. Los resultados fueroncomparados por ANOVA seguido de la prueba de Tukey (p<0,05).Resultados: El método FBBB proporcionó estimaciones más altas que FC (4,5 veces en telencéfalo,8,4 en mesencéfalo, 5 en tallo encefálico, 7,2 en bazo, 68,5 en timo y 4 en tejido cardiopulmonar). Con respecto a los tratamientos, se halló con FBBB que el grupo tratado con AQB tenía un aumento del nivelde polifenoles en tallo encefálico (p<0,02). Con FBBB se detectó una disminución del contenido tímicode polifenoles tras el tratamiento con IP (p<0,005). Los cerebelos de los animales que recibieron IP y los telencéfalos de C mostraron diferencias significativas al ser analizados con FC (p<0,05, p<0,0035 respectivamente).Conclusiones: El método FBBB dio como resultado estimaciones más elevadas que FC, lo que podría estar relacionado con mayor especificidad de la técnica para reaccionar con compuestos fenólicos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240832,"idioma_id":4,"titulo":"Pharmacology and Toxicology of Polyphenols with Potential As Neurotropic Agents in Non-communicable Diseases","resumen":"Abstract: Background: The central nervous system (CNS) is involved in organic integration. Nervousmodulation via bioactive compounds can modify metabolism in order to prevent systemic noncommunicablediseases (NCDs). Concerning this, plant polyphenols are proposed as neurotropic chemopreventive\/therapeutic agents, given their redox and regulating properties.Objective: To review polyphenolic pharmacology and potential neurological impact on NCDs.Method: First, polyphenolic chemistry was presented, as well as pharmacology, i.e. kinetics and dynamics.Toxicology was particularly described. Then, functional relevance of these compounds was reviewedfocusing on the metabolic CNS participation to modulate NCDs, with data being finally integrated.Results: Oxidative stress is a major risk factor for NCDs. Polyphenols regulate the redox biology of different organic systems including the CNS, which participates in metabolic homeostasis. Polyphenolic neurotropism is determined by certain pharmacological characteristics, modifying nervous and systemic physiopathology, acting on several biological targets. Nonetheless, because these phytochemicals can trigger toxic effects, they should not be recommended indiscriminately.Conclusion: Summing up, the modulating effects of polyphenols allow for the physiological role of CNS on metabolism and organic integration to be utilized in order to prevent NCDs, without losing sight of the risks.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240833,"idioma_id":4,"titulo":"Regional oxidative stress in encephalon of female mice with polyphenolic exposure from tea extracts in oral overweight plant-based treatment","resumen":"Polyphenols provide by diet may act as antioxidant in the Central Nervous Systemand exert a protective effect on metabolic diseases. The aim of this study was toestablish tea extract effects on oxidative status and murine overweight in accordancewith polyphenolic availability in different encephalic regions. Methods: Balb\/cmice (female, n>3) with overweight received for 15 days 100 mg\/Kg\/d of extractfrom Lantana grisebachii, Aspidosperma quebracho-blanco, or Ilex paraguariensisextracts and control group (received water without extract). Body weight gain wasrecorded regularly. Polyphenols, hydroperoxides (HP), lipid peroxides (LP), andsuperoxide anion (SO) were measured in brain (telencephalon and diencephalon),midbrain, brainstem and cerebellum. Results were compared by ANOVA followedby the Tukey test (P<0.05). Results: A. quebracho-blanco-based treatment decreasedweight gain and increased polyphenols in brainstem (p<0.02), although it concomitantly increased SO and LP in this region (p=0.0029 and p=0.0280, respectively).L. grisebachii-based treatment reduced oxidative markers differentially ineach region (p<0.05). I. paraguariensis-based treatment oxidized midbrain and cerebellum,although it was antioxidant in the brainstem (p<0.05). All treatments were antioxidant in telencephalon (p=0.0029). Conclusions: The A. quebracho-blanco extract was active on overweight and increased polyphenols in brainstem, with safe functional derivatives being required to avoid oxidative stress. Other extracts affected oxidative status in a region-dependent manner.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240834,"idioma_id":4,"titulo":"Bioavailability of phenolic compounds and redox state of murine liver and kidney as sex-dependent responses to phytoextracts","resumen":"Background: Plant extracts can be obtained to carry bioactive compounds, useful for prevention and treatment of different illnesses. This also supports the intake of teas as functional beverages. Nonetheless, it is incompletely known whether these extracts can act as effective sources and vehicles de phenolic compounds (phenolics\/polyphenols) to reach their targets. Objective: To establish whether phytoextract ingestion modified in a sex-dependent manner the phenolic bioavailability and redox response in liver and kidney. Method: BALB\/C mice ingested for a month 100 mg\/Kg\/d of extracts (tea-like) from Aspidosperma quebracho-blanco (AQB), Lantana grisebachii (LG) or Ilex paraguariensis (IP). Then, phenolics, peroxides and nitrites were analyzed by spectrophotometry. Also, phenolic permeation from digested and undigested extracts was evaluated in vitro with a rat jejunum-based assay. Results: Phenolic permeation depended on extract digestion. In males, IP showed a special time course of hepatic phenolics, whereas all extracts decreased renal phenolics at 15 days. Extracts induced hepatic lipoperoxides at 15 days. LG reduced renal hydroperoxides at 15 days and hepatic nitrites at 30 days, whereas AQB and IP reduced renal lipoperoxides and nitrites at 30 days. In females, extracts reduced hydroperoxides, with LG and AQB also reducing lipoperoxides. IP increased renal lipoperoxides at 30 days. Conclusion: IP was a relevant phenolic source. Sex-dependent responses were found in all variables, which should be considered to prevent misleading generalizations in phytodrug bioprospecting.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240835,"idioma_id":5,"titulo":"Modificaciones en el nivel de anión superóxido en leche materna, según la ingesta de flavonoides y carotenoides","resumen":"Objetivo. Asociar la ingesta de flavonoides y carotenoidescon el nivel en leche materna del anión superóxido, comomarcador de estrés oxidativo. Material y métodos.Durante el periodo 2013-2015 se estudió a 100 mujereslactantes de Córdoba (Argentina), dentro los primeros seismeses posparto; se evaluaron sus datos sanitarios, ingestaalimentaria y nivel lácteo del anión con regresión logísticamúltiple. Resultados. La ingesta de flavonoides, carotenoidesprovitaminas A y carotenoides no provitaminas fue de 72(61) mg\/día, 1 813 (1 657) µg\/día y 5 427 (3 664) µg\/día, respectivamente.El anión se asoció con la ingesta de flavanoles(RM=1.081; IC95 1.001-1.167) y flavanonas (RM=1.025; IC951.001-1.048). No se observó este efecto con otros flavonoi- des ni con los carotenoides. Conclusiones. La ingesta deflavanoles y flavanonas aumenta el riesgo de oxidación láctea,lo cual es relevante para realizar recomendaciones dietéticas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240836,"idioma_id":4,"titulo":"A combined experimental and molecular simulation study of factors influencing interaction of quinoa proteins&ndash;carrageenan","resumen":"The interaction between quinoa proteins isolate (QP isolate) and the negatively charged polysaccharide iota-Carragennan (Carr) as a function of pH was studied. Experimental measurements as turbidity, hydrophobic surface, zeta-potential, and hydrodynamic size were carried out. Associative interaction between QP and Carr was found in the pH range between 1 and 2.9. When both molecules are negatively charged (pH &gt; 5,5), a pure Coulombic repulsion regime is observed and the self-association of QP due to the Carr exclusion is proposed. In the intermediate pH range, the experimental data suggests that the charge regulation mechanism can overcome the electrostatic repulsion that may take place (and an attraction between QP and Carr can still be observed). Computational simulations by means of free energy derivatives using the Monte Carlo method were carried out to better understand the interaction mechanism between QP and Carr. QP was modeled as a single protein using one of the major proteins, Chenopodin (Ch), and Carr was modeled as a negatively charged polyelectrolyte (NCP) chain, both in the cell model framework. Simulation results showed attractive interactions in agreement with the experimental data.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240837,"idioma_id":4,"titulo":"Astrocyte Apoptosis and HIV Replication Are Modulated in Host Cells Coinfected with Trypanosoma cruzi","resumen":"se adjunta pdf","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240838,"idioma_id":4,"titulo":"CD4 + T cells and natural killer cells: Biomarkers for hepatic fibrosis in human immunodeficiency virus\/hepatitis C virus-coinfected patients","resumen":"AIM:To characterize peripheral blood natural killer (NK) cells phenotypes by flow cytometry as potential biomarker of liver fibrosis in human immunodeficiency virus (HIV)\/hepatitis C virus (HCV) coinfected patients.METHODS:Peripheral mononuclear cells from 24 HIV\/HCV (HBV negative) coinfected and 5 HIV\/HCV\/HBV seronegative individuals were evaluated. HIV\/HCV coinfected patients were divided in to groups: G1, patients with METAVIR F0-F2 and G2, patients with METAVIR F3-F4. NK surface cell staining was performed with: Anti-CD3(APC\/Cy7), anti-CD56(PE\/Cy5), anti-CD57(APC), anti-CD25(PE), anti-CD69(FITC), anti-NKp30(PE), anti-NKp46(PE\/Cy7), anti-NKG2D(APC), anti-DNAM(FITC); anti-CD62L (PE\/Cy7), anti-CCR7(PE), anti-TRAIL(PE), anti-FasL(PE), anti CD94(FITC). Flow cytometry data acquisition was performed on BD FACSCanto, analyzed using FlowJo software. Frequency of fluorescence was analyzed for all single markers. Clinical records were reviewed, and epidemiological and clinical data were obtained.RESULTS:Samples from 11 patients were included in G1 and from 13 in G2. All patients were on ARV, with undetectable HIV viral load. Liver fibrosis was evaluated by transient elastography in 90% of the patients and with biopsy in 10% of the patients. Mean HCV viral load was (6.18 ± 0.7 log10). Even though, no major significant differences were observed between G1 and G2 regarding NK surface markers, it was found that patients with higher liver fibrosis presented statistically lower percentage of NK cells than individual with low to mild fibrosis and healthy controls (G2: 5.4% ± 2.3%, G1: 12.6% ± 8.2%, P = 0.002 and healthy controls 12.2% ± 2.7%, P = 0.008). It was also found that individuals with higher liver fibrosis presented lower CD4 LT count than those from G1 (G2: 521 ± 312 cells\/&#956;L, G1: 770 ± 205 cells\/&#956;L; P = 0.035).CONCLUSION:Higher levels of liver fibrosis were associated with lower percentage of NK cells and LTCD4+ count; and they may serve as noninvasive biomarkers of liver damage.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240839,"idioma_id":4,"titulo":"Interaction of Mal de Río Cuarto virus (Fijivirus genus) proteins and identification of putative factors determining viroplasm formation and decay","resumen":"Mal de Río Cuarto virus (MRCV) is a member of the Fijivirus genus, within the Reoviridae family, that replicates and assembles in cytoplasmic inclusion bodies called viroplasms. In this study, we investigated interactions between tenMRCV proteins by yeast two-hybrid (Y2H) assays and identified interactions of non-structural proteins P6\/P6, P9-2\/P9-2 and P6\/P9-1. P9-1 and P6 are the major and minor components of the viroplasms respectively, whereas P9-2 is an N-Glycosylated membrane protein of unknown function. Interactions involving P6 and P9-1 were confirmed by bimolecular fluorescence complementation (BiFC) in rice protoplasts. We demonstrated that a region including a predicted coiled-coil domain within the C-terminal moiety of P6 was necessary for P6\/P6 and P6\/P9-1 interactions. In turn, a short C-terminal arm was necessary for the previously reported P9-1 self-interaction. Transient expression of these proteins by agroinfiltration of Nicotiana benthamiana leaves showed very low accumulation levels and further in silico analyses allowed us to identify conserved PEST degradation sequences [rich in proline (P), glutamic acid (E),serine (S), and threonine (T)] within P6 and P9-1. The removal of these PEST sequences resulted in a significant increase of the accumulation of both proteins.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240841,"idioma_id":5,"titulo":"Morfología y anatomía foliar y caulinar de Scutia buxifolia (Rhamnaceae)","resumen":"Scutia buxifolia Reisseck (Rhamnaceae) vulgarmente conocida como ?coronillo?, es una especie endémica de los talares del Norte y Este de Buenos Aires. Es un arbusto espinoso o un pequeño árbol de 2 a 6 m de altura, con ramas tetragonales y espinas axilares. Es una especie utilizada en medicina popular como diurética, cardiotónica y anti-hipertensiva. En este estudio se analizó la estructura foliar y caulinar de S. buxifolia con el objetivo de aportar caracteres morfológicos y micrográficos, por medio de técnicas farmacobotánicas. En los disociados de las hojas se distinguieron estomas anomocíticos y hexacíticos, cristales romboidales, drusas y vainas cristalíferas acompañando a las tráqueas. En transcor te, las láminas foliares presentaron epidermis unistrata, idioblastos cristalíferos, estomas en la epidermis abaxial, mesófilo dorsiventral,colénquima angular abaxial y vainas esclerenquimáticas o parenquimáticas que rodean los haces vasculares. Los diafanizados foliares mostraron venación primaria simple y pinada, y venación secundaria camptódroma broquidódroma; venación marginal ojalada e incompleta y aréolas bien desarrolladas. En los tallos primarios y secundarios, y en las espinas caulinares se observaron esclereidas, drusas, cristales romboidales y cúbicos. Los resultados obtenidosaportaron caracteres morfológicos y anatómicos diagnósticos para la caracterización e identificación de S. buxifolia","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240843,"idioma_id":5,"titulo":"El pasado repensado, repasado y remendado","resumen":"La memoria reúne los vestigios de lo sido y ayuda a proyectar la vida construyendo, con ese anudamiento de dos dimensiones temporales, una representación de lo que somos. De hecho, la subjetividad como presencia de sí emerge de ella. La memoria nos labra pero, es justo también decir que, nosotros la moldeamos a ella. Toda historia de vida es producto de esta dialéctica donde se funden y refunden memoria e identidad. Así componemos y recomponemos un pasado autobiográfico estable, verosímil y previsible, donde los proyectos de vida cobran sentido y donde la sucesión de episodios pierde su carácter aleatorio y desordenado para integrarse en un eje temporal continuo. Cualquier discurso de presentación del sí propio tiene la forma de una totalidad significante integrada pero esa unidad está realizada con remembranzas de una serie de acciones deshilachadas, fragmentadas, discontinuas. De igual manera a como procedemos con un personaje histórico que intentamos recrear, nos aferrarnos a los testigos que consideramos ?por afecto- fiables, a certificaciones burocráticas, a fotografías o filmaciones para ir engarzando en una línea nuestros recuerdos. Muchísimos más, quedan sumergidos en el río Leteo. Como decía el perspicaz Nietzsche: memoria es recuerdo y olvido. Esta reconstrucción de nuestra personal memoria de vida a partir de luces y sombras, decires y secretos, presencias y ausencias, certidumbres y distorsiones, nos da indicios de las complejidades insertas en ese tejer la urdimbre del pasado y nos habilita la sospecha sobre algunos recuerdos incorporados. Pero también esta práctica de rescate del flujo de lo vivido que todos hacemos y padecemos, nos deja en claro que no hay memoria individual sino siempre entrelazada.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240844,"idioma_id":5,"titulo":"ANÁLISIS MULTITEMPORAL DE LA DISTRIBUCIÓN ESPACIAL DE INCENDIOS EN LA COBERTURA VEGETAL DE LA CUENCA DEL RÍO GUALEGUAY,  ENTRE RÍOS, ARGENTINA","resumen":"El objetivo de este trabajo fue analizar la distribución espacial y temporal de los incendios en la cuenca del Río Gualeguay y la relación de esa distribución con los tipos de cobertura del suelo. El área de estudio fue la cuenca del Río Gualeguay situada en la Provincia de Entre Ríos, Argentina. Los materiales fueron Imágenes Landsat TM y coberturas de focos de calor del Sistema de Gestión de Recursos para Manejo del Fuego - FIRMS, el software QGIS e Idrisi. La metodología articuló, en una primera etapa, clasificaciones no supervisadas, supervisada, segmentación y agrupamiento temático para obtener el mapa final de cobertura de las tierras. En la segunda etapa, la Carta de puntos de calor y el mapa de coberturas fue combinada para obtener una tabla de frecuencias y distribución anual de incendios por clases temáticas. Los resultados muestran que las clases con mayor incidencia de incendios fueron principalmente tres: 'las áreas terrestres cultivadas y\/o manejadas', 'pajonal' y 'arbórea terrestre abierto'. Se recomienda el uso de esta información para el manejo del fuego, asignación de recursos y estudiar su utilidad para detección de desmontes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240845,"idioma_id":4,"titulo":"Dimensional considerations of test pieces for belly-flop angles test of fat softness","resumen":"The belly-flop angle test is a simple measure for determining the softness of fat in pork bellies. This study analyses the belly-flop angle test from simple beam-bending theory and highlights the relationships between angular deflection, test piece dimensions, stiffness and intrinsic characteristics of the sample, based on simple engineering terms. Results indicate a positive correlation between belly-flop angle versus belly thickness and fat melting point. Belly thickness was also related to melting point in our test specimens. By correcting the results for specimen dimensions, a more accurate relationship between belly-flop angle and fat stiffness can be obtained.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240850,"idioma_id":5,"titulo":"Tecnología ósea en la depresión del río Salado (provincia de Buenos Aires)","resumen":"En el humedal de la Depresión del río Salado -habitado durante el Holoceno tardío (entre 2400 y400 años AP) por grupos de expertos alfareros- los recursos faunísticos más explotados fueronespecies de porte menor como coipo, peces, aves terrestres y acuáticas. Los cérvidos fueronrecursos complementarios. Estos grupos desarrollaron estrategias de aprovisionamiento ymanufactura de huesos, además de incisivos de coipo, para utilizar como instrumentos. Seanalizaron tecno-morfológicamente 25 piezas óseas provenientes de los sitios LG1 (n=4) y LG5(n=21) con evidencias de formatización antrópica. Se tomaron los siguientes parámetros:elemento, tipo de fractura, dimensiones y presencia\/ausencia de huellas; asimismo se registró la incidencia de agentes y procesos tafonómicos sobre los elementos. Se identificaron varios taxa: Aves (=4), Rallidae (n=1), Mammalia (n=2), Cervidae (n=4), Ozotoceros bezoarticus (n=8), Blastoceros dichotomus (n=1), Rodentia (n=1), Rodentia cf. Caviinae (n=3) y Myocastor coypus (n=1). Se definieron los Grupos Morfológicos: tubos, biseles, puntas (ahuecada, acanalada,semiacanalada, roma) y aquellos que no pudieron asignarse a los ya definidos, se indicaron como indeterminados. Se discuten posibles funciones y se propone que esta tecnología ósea es parte del uso integral de los recursos faunísticos del área.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240852,"idioma_id":4,"titulo":"ISOLATION OF SAPROPHYTIC LEPTOSPIRA SP. FROM A SELECTED ENVIRONMENTAL WATER SOURCE OF ARGENTINA","resumen":"Ten Leptospira spp. strains were isolated from water samples from Nievas stream, Olavarría, Buenos Aires province (Argentina). The isolates showed the typical motility and morphology of the genus Leptospira under dark field microscopy, developing in liquid EMJH medium after eight days of incubation at 13 °C and 30 °C. All isolates were negative by the Multiple Locus Variable Number Tandem Repeat Analysis (MLVA). Molecular identification by 16S rRNA gene sequencing identified all isolates as nonpathogenic leptospires. Four isolates showed a genetic profile identical to that of the reference strain Leptospira biflexa serovar Patoc, and six isolates revealed sequence similarities within the 97?98% range, closely related to Leptospira yanagawae and Leptospira meyeri, respectively. Strains ScialfaASA42, ScialfaASA45, ScialfaASA44, ScialfaASA47, ScialfaASA49, ScialfaASA50 and ScialfaASA51 possibly represent a novel species of the genus Leptospira.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240854,"idioma_id":4,"titulo":"Chronic hepatitis C liver microenvironment: the role of the Th17\/ Treg interplay related to fibrogenesis.","resumen":"The role of the different lymphocyte populations in liver microenvironment of chronic hepatitis C (CHC) patients is still matter of debate. Since Th17 and Treg have opposite functions, their balance could affect disease progression. The aim was to explore liver microenvironment and its peripheral blood counterpart in adult CHC patients. CD4+ lymphocytes were predominant in the liver, with high Foxp3+ but low IL-17A+ frequency. IL-17A+ lymphocytes and IL-17A+\/Foxp3+ ratio displayed association with advanced fibrosis (p=0.0130; p=0.0236, respectively), while Foxp3+ lymphocytes and IL-10 expression level inversely correlated with fibrosis severity (p= 0.0381, p=0.0398, respectively). TGF-&#946;\/IL-6 ratio correlated with IL-17A+\/Foxp3+ ratio (p=0.0036, r=0.5944) and with IL-17A+ lymphocytes (p=0.0093; r=0.5203). TNF-&#945; and TGF-&#946; were associated with hepatitis severity (p=0.0409, p=0.0321). Peripheral blood lymphocyte frequency was not associated with liver damage.There are functionally different immune cell populations actively involved in liver damage, but the liver cytokine milieu actually drives the pathogenesis. The intrahepatic Foxp3+ lymphocytes predominance beside the low IL-17A+ lymphocytes frequency, delineate a skewed IL-17A+\/Foxp3+ balance towards Foxp3+ lymphocytes. However, the IL-17A+ lymphocytes association with advanced fibrosis denotes their role in the pathogenesis. Therefore, the interplay between Th17 and Treg conditions liver fibrogenesis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240857,"idioma_id":4,"titulo":"Molecular mapping of the genomic region conferring resistance to soybean stem canker in Hutcheson soybean.","resumen":"Abstract Genetic resistance to soybean stem canker,caused by the fungus Diaporthe phaseolorum var.meridionalis (Dpm), is controlled by five major, dominant,nonallelic genes Rdm1 to Rdm5. A genomic region containing the Rdm4 and Rdm5 genes was first described in Hutcheson soybean, where they were found to confer specific resistance to Argentinean physiological races of Dpm. Here, we report the genetic mapping of Rdm4 and Rdm5 loci using two pheno- and genotypicallycharacterized F2:3 populations derived from Hutcheson cultivar. The mapping populations were screened with amplified fragment length polymorphism (AFLP) markers using bulk segregant analysis, and withsimple sequence repeat (SSR) markers. Linkage analysis indicated that the Rdm4 and Rdm5 resistance loci were located in a genomic region collinear with themolecular linkage group (MLG) A2 (chromosome 8)of the soybean genetic map. The linkage group contains two SSR markers, Sat_162 and Satt233, flanking the Rdm4 and Rdm5 loci. These SSR will be useful toincrease the efficiency of selection in breeding programs aimed to incorporate Rdm4 and Rdm5 genes into soybean elite germplasm.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240859,"idioma_id":5,"titulo":"Productividad y calidad nutricional de especies forrajeras tipicas en mallines de la Patagonia Austral (Argentina)","resumen":"planteó un estudio con el objetivo de evaluar la productividad y la calidad nutricional de las principales especies forrajeras nativas con aptitud de corte en mallines del SO de Santa Cruz. En este contexto, en clausuras permanentes instaladas en dos mallines húmedos seleccionados se realizaron durante dos años cortes manuales de la vegetación en tres estados fenológicos (vegetativo, inicio de floración y floración avanzada) del pastizal. A la cosecha, se determinó la Biomasa Aérea Acumulada (BAAc) y el Material Vivo (MV) y Muerto del forraje recolectado. En laboratorio, se realizaron determinaciones químicas de la Materia Seca Total (MST), cenizas (CEN), Proteína Bruta (PB), Fibra en Detergente Neutro con alta amilasa (aFDNMO) y Ácido (FDAMO) y Lignina en Detergente Ácido (acLDAMO), todos expresados libre de cenizas. También se determinó la Digestibilidad de la Materia Seca (DMS) y calculó la Biomasa Aérea Acumulada Digestible (BAAcDig). Los resultados se analizaron según un arreglo factorial 3 × 2, i.e. Estado Fenológico (EF, Vegetativo, Inicio de Floración y Floración Avanzada) y Año (2006\/07 y 2007\/08). El arreglo factorial se incluyó en un diseño en bloques completos aleatorizados (dos bloques correspondientes a los mallines seleccionados). El estudio detectó un aumento (p<0,05) de la BAAc y BAAcDig del pastizal al inicio de la floración respecto al estado vegetativo y una disminución (p<0,05) del MV y del contenido de PB con el avance del EF. Además, en el estado de floración avanzada se reportaron las mayores (p<0,05) concentraciones de MST, aFDNMO, FDAMO y acLDAMO y el menor contenido (p<0,05) de DMS respecto a los estadios fenológicos anteriores. Se concluye que sería recomendable realizar el corte del mallín para conservar durante el estado inicial de floración del pastizal para optimizar la biomasa acumulada de la vegetación con una calidad nutricional adecuada.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240860,"idioma_id":4,"titulo":"Performance comparison of conventional, hybrid, hydrogen and electric urban buses using well to wheel analysis","resumen":"This work presents a new method to compare energy and environmental performances of five types of urban passenger buses powertrains using a multiphysic index on the basis of a well to wheel analysis. The well to tank step was made for present and future (year 2030) scenarios using different assumptions for the years to come and obtaining various energy and environmental parameters. Additionally, the tank to wheel analysis was performed using dynamic models of vehicles, two different driving cycles and four ranges. Later both stages were integrated in a well to wheel stage where relevant indexes were proposed and discussed. In order to properly asses the different hypotheses for systems, range, cycles and scenarios; a multiphysics indicator (Integrated Sustainability Index), valued between zero and one was used. The best results were achieved by hybrid electric vehicles for short and medium terms. In the long term battery electric vehicles are convenient only for short driving range, while the fuel cell buses yield good performances for more extended driving ranges. For the cleaner powertrains to be competitive, hydrogen production must be fed with clean and renewable energies and the renewable energy share in the electric energy matrix should be considerably high.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240861,"idioma_id":4,"titulo":"Energy management control design for fuel cell hybrid electric vehicles using neural networks","resumen":"The design and optimization of hybrid electric vehicle powertrains can take a great benefit from mathematical models which include auxiliary management and control strategies of the energy fluxes: the use of virtual platforms reduces the expensive and time-consuming experimental activity. In this work the authors developed an online Energy Management System (EMS) controller for a FCHEV, designed to employ the same energy management over a wide range of driving style types. The controller was designed by using neural networks (NN), which were trained with the optimal power flux distribution between a fuel cell system and a battery system that minimizes the overall equivalent energy consumption. The optimal solution was obtained by carrying out a gradient-based method minimization over eight different driving cycles, and using a dynamic lumped parameter mathematical model of a FCHEV fed by hydrogen and Li-ion batteries. A quantitative and qualitative analysis was made showing the networks performances over different type of cycles. Through this analysis, a suitable classification into two cycle categories is provided, covering most of the possible driving styles with two of the developed controllers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240864,"idioma_id":5,"titulo":"Pobres esperando, amontonados","resumen":"-","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240865,"idioma_id":5,"titulo":"Verdad, Justicia y examen de conciencia","resumen":"-","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240866,"idioma_id":5,"titulo":"Grieta o Fraternidad","resumen":"-","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240867,"idioma_id":5,"titulo":"Escuchar a los que menos tienen","resumen":"-","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240875,"idioma_id":5,"titulo":"EFECTOS DISTORSIVOS DE LA INFLACION ACUMULADA SOBRE LA INFORMACION FINANCIERA. CUANTIFICACION DE SU INCIDENCIA SOBRE ALGUNAS VARIABLES RELACIONADAS CON LOS RESULTADOS PERIODICOS","resumen":"Losestados contables en Argentina son elaborados en moneda nominal, conforme loestablecido por la norma contable vigente. El límite mínimo establecido paraajustar la información contable no se alcanzó, de acuerdo a los índicespublicados oficiales. Sin embargo, desde que fue discontinuada la aplicacióndel ajuste por inflación, en el año 2003, el incremento acumulado del nivelgeneral de precios supera el 330%. La informacióncontable expresada en moneda nominal en contextos inflacionarios resultadistorsionada y no es posible determinar el resultado del ejercicio real, nilograr que la información referida sea confiable y útil para que sus usuariostomen decisiones basadas ella. Entre otras cuestiones, es la base paradeterminar la rentabilidad, la distribución de dividendos y el impuesto a lasganancias. Con el objeto de verificar empíricamente la incidencia de lainflación en los resultados periódicos de empresas argentinas, se analizaronlos estados contables publicados por un grupo de empresas locales y, aplicandoel método establecido por la RT 6, se determinaron resultados reales entre 2004y 2014, analizando las diferencias con los resultados nominales. Se observó quealgunas empresas presentan diferencias significativas entre el resultadoacumulado nominal y el real; que el efecto del impuesto a las ganancias sobrelos resultados reales es superior al producido sobre los resultados nominales,llegando a tasas reales superiores al 100% o a la determinación del tributosobre un resultado real negativo. Losresultados obtenidos permiten ratificar los efectos distorsivos sobre lainformación contable que produce la utilización de moneda nominal en contextosinflacionarios.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240876,"idioma_id":5,"titulo":"LA PROFESIÓN CONTABLE Y SU RELACIÓN CON EL CAPITALISMO GLOBAL","resumen":"Este trabajo seenmarca en el Proyecto de Investigación ?Formación universitaria y desarrolloprofesional del contador público en un contexto globalizado?.&nbsp; En él se propone revisar la vigencia deciertos contenidos teóricos y prácticos establecidos en el plan de estudio algraduado de la carrera de Contador Público- de la Facultad de CienciasEconómicas de la Universidad Nacional de Rosario -para el ejercicio de laprofesión en un contexto globalizado. Para intentar abordar dicha propuesta,surgen problemáticas que requieren ser dilucidadas, una tiene que ver conresponder qué se entiende por contexto globalizado, otra es determinar cuálesde las características que definen dicho contexto afectan directamente laprofesión contable, y por último, identificar cuál es su incidencia en elámbito del saber contable. Es objetivo del presente trabajo avanzar en labúsqueda de respuestas a estas preguntas. Para ello, en primer término seexplicita la conformación de la estructura de poder del capitalismo globalidentificando sus características más relevantes y aquellas que influyen en elámbito en el que el profesional contable se desarrolla, luego se explicita laincidencia en la profesión contable en cuatro variables que se consideranrelevantes: la dimensión internacional, la tecnología, la relación teoría prácticay la ética. Se parte de entender que la profesión contable no es solamente unmedio de satisfacer lo que el mercado laboral demanda, ni se define simplementepor la búsqueda de la realización personal -vocación-, tampoco es la aplicaciónde una mera técnica, ni lo que se realiza a través de un ordenador, sino que estodo esto y mucho más. Lo que distingue al saber profesional es que debe servalidado por la sociedad en tanto que su ejercicio afecta al interés público. &nbsp;Es un saber válido para sí del individuo y unsaber socialmente construido y admitido. La tarea de interpretar cómo seconstruye ese saber es lo que motiva la realización de este trabajo. Unaaproximación al mismo se presentó en las XXII Jornadas de Epistemología deCiencias Económicas, en el área Epistemología de la Contabilidad, y seincorporan al presente las oportunas intervenciones recibidas por parte de losasistentes. Se incorporan además los aportes de integrantes del grupo deinvestigación, quienes profundizan los temas abordados. En cuanto a lametodología, el trabajo es el resultado de una investigación interdisciplinariade carácter exploratorio descriptivo. La misma se realizó a partir de unenfoque teórico metodológico cualitativo que hizo hincapié en el análisisdocumental de textos. A su vez se aplicó el análisis de contenido cualitativopara tratar de interpretar el material analizado y establecer inferencias,profundizando en el contexto social donde se desarrolla el mensaje. Seconsidera que dicha metodología, permitió construir espacios de interpretaciónadecuados y útiles para la reflexión actual sobre la temática propuesta. Sedespliegan conceptos sobre el capitalismo global. Luego se explora el conceptode profesión contable y por último se abordan las dimensiones de la profesiónque se consideran más afectadas por la globalización, para por último esbozaralgunas reflexiones. Con este trabajo se espera poder contribuir a los debatespermanentes sobre la relación existente entre la formación académica y elejercicio de la profesión contable dado que la justificación teórica y ladimensión social orientaron al mismo. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240877,"idioma_id":5,"titulo":"Ranqueles, ?indios chilenos? y refugiados unitarios en la Frontera Sur de Córdoba (1836-1844).","resumen":"Desde fines del siglo XVIII y hasta 1879, losranqueles habitaron buena parte de la pampa central argentina. Su itinerario seasemeja al de otros grupos indígenas del continente americano que resistieronel avance hispano criollo. Pero también exhibe numerosas particularidades dignasde ser abordadas, especialmente durante la etapa que se inaugura con la llegadade Juan Manuel de Rosas al gobierno de la provincia de Buenos Aires, quien sepropuso eliminarlos del espacio que ocupaban en el caldenar pampeano. Para elloplanificó una serie de acciones que incluyeron fuerzas de otras provincias cuyosterritorios limitaban con los indígenas, como la ?Campaña al Desierto? de 1833y 1834. Esta animosidad contra los ranqueles se fundaba no sólo en la amenazade los ataques sobre las estancias y poblados fronterizos sino también en laarticulación de éstos con otras fuerzas sociales, como los ?indios chilenos? ylos unitarios derrotados que se refugiaron en las tolderías del ?Mamil Mapú? enla pampa central. El trabajo está dedicado a examinarestas articulaciones políticas indígeno-cristianas ocurridas en la Frontera Sur deCórdoba entre 1836 y 1851.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240878,"idioma_id":5,"titulo":"INCIDENCIA DE LA INFLACIÓN SOBRE LA INFORMACIÓN FINANCIERA. SU ANÁLISIS A TRAVÉS DE INDICADORES","resumen":"Conformeal marco normativo vigente en Argentina, los estados contables deben elaborarseen moneda homogénea, de fecha de cierre de ejercicio, cuando la tasa acumuladade inflación en tres años alcance o supere el 100% -medida sobre la base delIPIM publicado por el INDEC-. Deno alcanzar ese límite cuantitativo, los informes financieros para usuariosexternos deben presentarse en moneda nominal.Estasafirmaciones son válidas, tanto si se trata de empresas que cotizan sus títulosde capital o deuda y que se encuentran en el ámbito de supervisión de la CNV,como si el ente emisor no tiene esa condición. La inflación distorsiona la información contenida en los estadoscontables al no reconocer los efectos que producen los cambios en el poderadquisitivo de la moneda. La inflación o deflación es un hecho del contexto cuyos efectos sobre elpatrimonio del ente emisor de estados contables deberían ser reconocidos ymedidos. Su falta de reconocimiento&nbsp;integral&nbsp; incide sobre laaproximación de dicha información a la realidad económica que deberíarepresentar. La utilización de lamoneda nominal, ignorando los efectos de la&nbsp;inflación, genera múltiples distorsiones que repercuten en la calidad delos estados contables. Una deficiencia quemerece destacarse es la imposibilidad de determinar la verdadera gananciadevengada.La significación desus efectos depende no sólo de la inflación periódica y acumulada, sino tambiénde la estructura patrimonial del ente.&nbsp;Mayor endeudamiento en moneda local podría amortiguar el efecto negativode la inflación.Son objetivos paraeste estudio:?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Verificar empíricamente el impacto de la inflaciónen los resultados periódicos de un grupo de empresas argentinas cotizantesdurante el período 2004 a 2014.?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;Determinar lamagnitud de la diferencia entre los resultados expresados en términos reales ylos nominales.?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Comparar los índices de variación del resultado realsobre el nominal con los índices de endeudamiento de cada ejercicio analizado,buscando relaciones de causalidad.El abordaje metodológico contempló la aplicación del proceso secuencialestablecido por&nbsp; la RT 6, que permitedeterminar los resultados periódicos en moneda homogénea de la fecha de cierrede los estados contables anuales, a una muestra de empresas seleccionas, entre2004 y 2014. Fueron seleccionadas cinco empresas argentinas, cuyos estadoscontables se encuentran disponibles en la página web de la CNV. En este trabajo sedeterminaron y mostraron?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;las diferencias entre los resultados nominalesy reales?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; lacomparación entre las variaciones entre esos resultados y los índices deendeudamiento, a los fines de confirmar la hipótesis.Las tareas a abordara partir de ahora son:?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; labúsqueda de factores que inciden para no confirmar la hipótesis.?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; laidentificación de los factores adicionales que afectan a la informacióncontenida en los estados contables en moneda nominal, en contextosinflacionarios.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240879,"idioma_id":5,"titulo":"REHENES Y CAUTIVOS VIOLENCIA Y DIPLOMACIA EN LA FRONTERA SUR DE CÓRDOBA (1835-1861)","resumen":"En el marco de los estudiossobre la Frontera Sur Argentina, el trabajo examina situaciones de tensióndiplomática entre cristianos e indígenas en el lapso comprendido entre 1835 y1861 que permiten advertir el uso político que se hacía de rehenes y cautivos.Se identifican dos momentos en las relaciones interétnicas en los que primarondeterminar formas de cautiverio: la primera corresponde al período 1835-1852durante el cual predomina una política basada en la toma de cautivos (cristianos e indígenas) y en el uso derehenes siguiendo la práctica colonial. Elsegundo lapso se extiende entre 1852-1861 cuando el interés por la recuperaciónde cautivos cristianos e indígenas en el tramo cordobés queda en unsegundo plano. La sanción de la Constitución Nacional de 1853 habríarepercutido sobre las prácticas diplomáticas de la frontera ya que comienza acaducar la vieja costumbre de entregar rehenes como garantía de lo pactado. Ladocumentación consultada, que proviene en su totalidad del Archivo Histórico dela Provincia de Córdoba (AHPC), está compuesta por la correspondenciaintercambiada entre el gobierno provincial, las autoridades fronterizas y loscaciques ranqueles","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240880,"idioma_id":5,"titulo":"Discursos culturales en torno a las maternidades. Sus tensiones.","resumen":"El presente trabajo es parte del Proyecto de Investigación cuatrienal (2016-2020) titulado ?Lo femenino y lo maternal en nuestra época?. En esta oportunidad presentamos los modos actuales que predominan en la cultura para ?decir? las maternidades. Retomamos la diferencia que planteamos en trabajos anteriores, entre experticia y experiencia, para sumarle a los primeros, pertenecientes a la divulgación científica, los discursos de la publicidad, como su continuación; y como reverso de las postulaciones positivistas, tomamos el discurso literario conjugado en la obra de Ariana Harwicz; que apunta a la experiencia singular.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240881,"idioma_id":5,"titulo":"Expectativas de inserción laboral en adolescentes de sectores urbanos","resumen":"Este trabajo exploró los proyectos de vida con especial orientación en expectativas de inserción laboral de jóvenes que cursan el último año del ciclo educativo medio en CABA y conurbano bonaerense sin experiencia laboral. Objetivos específicos: a) Analizar el proyecto de vida de los jóvenes respecto de sus expectativas de inserción laboral. b) Analizarlos obstáculos que identifican en ese proceso. c) Analizar la presencia de conciencia crítica respecto de la situación laboral en general. d) Analizar la coherencia y consistencia entre las expectativas laborales y el proyecto de vida como configuración general. Se realizó análisis del discurso de entrevistas administradas. Según la hipótesis de trabajo la transición de los jóvenes hacia la adultez presenta una diversidad de expresiones que distan de considerarse como un modelo lineal de curso de vida; la expectativa de integración social hacia la adultez no es equivalente a la expectativa de integración en el mercado laboral. Se concluyó que entrevistados tienen expectativas de continuar con sus estudios y la inserción laboral queda supeditada a las primeras. Manifiestan confianza en el propio esfuerzo personal y conciencia crítica centrada en la experiencia personal respecto de las condiciones laborales del sistema económico actual. Tienen conocimiento de las posibilidades de inserción laboral precarias, y la exigencia de mayores calificaciones para puestos de bajo perfil. No manifiestan urgencia por insertarse en mercado laboral.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240882,"idioma_id":5,"titulo":"Las ?huellas? sobre el saber técnico. Relatos sobre los itinerarios de formación de los estudiantes de comunicación social","resumen":"El presente artículo tiene como objetivo indagar y problematizar el lugar y la relevanciacognitiva de los conocimientos técnicos en los itinerarios de formación y las experienciaslaborales de los estudiantes de Comunicación Social (FCE-UNER).Metodológicamente, la indagación se encuadra dentro de los llamados estudioscualitativos, específicamente interpretativo-descriptivo y la técnica de investigación escogidafue la entrevista en profundidad. Se realizó un análisis interpretativo-crítico del corpus segúnuna hipótesis de lectura que apuntó a identificar las ?huellas? del sentido sobre el sabertécnico en los relatos de los estudiantes.Un primer análisis de las entrevistas evidencia la presencia de dos concepcionesdicotómicas sobre el saber técnico que entran en constante tensión al interior de lasprácticas de formación de los estudiantes de comunicación social.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240883,"idioma_id":5,"titulo":"EL PROCESO DE DOMESTICACIÓN DE LA TELEVISIÓN DIGITAL TERRESTRE. Un estudio de caso en la ciudad de Paraná, Entre Ríos, Argentina","resumen":"El objetivo del siguiente artículo es dar cuenta sobre las prácticas de consumo cultural asociadas a la Televisión Digital Terrestre (TDT) en usuarios de la ciudad de Paraná, Entre Ríos, en el cual nos cuestionamos en qué medida las ventajas comparativas que avizora la televisión digital respecto a la televisión analógica, generan nuevos hábitos de consumo audiovisual.Debido a la novedad y a la corta edad de la implementación de la TDT en nuestro país, hay pocas investigaciones disponibles y la mayoría de los trabajos académicos apuntan a describir el estado de implementación de las políticas de TDT. Por tanto, la originalidad de nuestro trabajo reside en recuperar la perspectiva teórica-metodológica anclada en los Estudios Culturales para re-pensar la relación entre las tecnologías y sus hábitos de uso y consumo.Para la construcción de los datos se utilizó la técnica de la entrevista en profundidad y se adoptó el modelo de ?domesticación de la tecnología? de Roger Silverstone para la organización del cuestionario. Respecto a la técnica para el análisis de los datos se optó por un análisis interpretativo-crítico de los nudos recurrentes de sentido que aparecen en el corpus de entrevistas en relación a las prácticas de consumos culturales asociados a la TDA. Los resultados de nuestra investigación muestran que los usuarios entrevistados afirmaron seguir teniendo los mismos hábitos de consumo que antes de la llegada de la televisión digital a sus hogares.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240890,"idioma_id":4,"titulo":"Efficacy of ceftaroline against methicillin-susceptible Staphylococcus aureus exhibiting the cefazolin high-inoculum effect in a rat model of endocarditis","resumen":"Certain Staphylococcus aureus strains exhibit an inoculum effect (InE) with cefazolin (CFZ) that has been associated with therapeutic failures in highinoculum infections. We assessed the in vitro activities of ceftaroline (CPT), CFZ, and nafcillin (NAF) against 17 type A &#946;-lactamase (&#946;la)-producing, methicillin-susceptible S. aureus (MSSA) strains, including the previously reported TX0117, which exhibits the CFZ InE, and its &#946;la-cured derivative, TX0117c. Additionally, we determined the pharmacokinetics of CPT in rats after single intramuscular doses of 20 and 40 mg\/kg of body weight and evaluated the activities of CPT (40 mg\/kg every 8 h [q8h]), CFZ, and NAF against TX0117 and TX0117c in a rat model of infective endocarditis. No InE was observed for CPT or NAF, whereas a marked InE was detected for CFZ (MIC, 8 to &#8805;128 &#956;g\/ml). CPT and NAF treatment against TX0117 resulted in mean bacterial counts of 2.3 and 2.1 log10 CFU\/g in vegetations, respectively, compared to a mean of 5.9 log10 CFU\/g in the CFZ-treated group (CPT and NAF versus CFZ, P = 0.001; CPT versus NAF, P = 0.9830). Both CFZ and CPT were efficacious against the &#946;la-cured derivative, TX0117c, compared to time zero (t0) (P = <0.0001 and 0.0015, respectively). Our data reiterate the in vivo consequences of the CFZ InE and show that CPT is not affected by this phenomenon. CPT might be considered for highinoculum infections caused by MSSA exhibiting the CFZ InE.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240896,"idioma_id":4,"titulo":"Influence of thermal treatments on the mechanical properties and the martensitic transformation in Fe-Pd-Mn ferromagnetic shape memory alloy","resumen":"The effects of high temperature thermal treatments on the hardening behaviour, the damping capacity and the martensitic transformation in Fe66.8Pd30.7Mn2.5 Ferromagnetic Shape Memory Alloy have been determined by mechanical spectroscopy. Annealing below 753 K, lead to a hardening of the alloy without a marked decrease in the damping capacity. In addition, they increase both the austenite finish transformation temperature and the intensity of the damping peak related to the martensitic transformation. This variation can be controlled by the small volume fraction precipitation of small &#945; phase particles. In contrast, thermal treatments performed above 753 K lead to a further hardening of the alloy, but they decrease the austenitic finish transformation temperature and the intensity of the damping peak related to the martensitic transformation; as a consequence of the decomposition of the metastable &#947; phase into the &#945;+&#947;1 stable phases. In addition, two new damping peaks related to the mobility of dislocations and grain boundaries have been discovered at around 700 K and 900 K, respectively.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240897,"idioma_id":4,"titulo":"Study of the martensitic transition in Ni-Mn-Sn-Ti ferromagnetic shape memory alloys","resumen":"In the present work, mechanical spectroscopy measurements as a function of temperature and strain have been performed in (at.%) Ni50Mn37Sn13-xTix (x=0, 0.5 and 2) ferromagnetic shape memory alloys in order both to study martensitic transition phenomenon and also to determine its temperature of appearance. For mechanical spectroscopy measurements, a five elements piezoelectric device recently developed has been used. In addition, other characterization techniques as, differential thermal analysis and superconducting quantum interference magnetic spectroscopy, were also used. Besides, relaxation processes near the martensitic transition temperature have been also observed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240898,"idioma_id":4,"titulo":"Denaturation processes of collagen from cow bones as a function of temperature","resumen":"The thermal stability of type I collagen from cow bones, either femur and ribs, was studied in the temperature range from 250 K up to 670 K by means of dynamic mechanical analysis, scanning electron microscopy and infrared absorption spectroscopy. Several stages of denaturation were found in the temperature range from 320 K up to 670 K. The experimental results reveal the denaturation processes which take place at the collagen including also the triple helix towards the random coil transition of the collagen fibrils.The differences between the denaturation processes in the femur and ribs are highlighted and the physical-chemical mechanisms controlling the denaturation processes are discussed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240899,"idioma_id":4,"titulo":"Influence of defects on the irreversible phase transition in the Fe-Pd doped with Co and Mn","resumen":"The appearance of BCT martensite in Fe-Pd-based ferromagnetic shape memory alloys, which develops at lower temperatures than the thermoelastic martensitic transition, deteriorates the shape memory properties. In a previous work performed in Fe70Pd30, it was shown that a reduction in defects density due to the structure recovery by thermal treatment above 673 K clearly stabilizes the alloy, reducing the non thermoelastic FCT-BCT transformation temperature, and increasing the temperature range where the thermoelastic FCT can occur. In the present work, the influence of quenched-in-defects upon the intensity and temperature of the thermoelastic martensitic (FCC-FCT) and the non thermoelastic (FCT-BCT) transitions in Fe67Pd30Co3 and Fe66.8Pd30.7Mn2.5 ferromagnetic shape memory alloys; is studied. In fact, dislocation dynamics has been studied by means of mechanical spectroscopy, while the martensitic transition temperatures have been determined through differential scanning calorimetry. A good correlation between the behaviour of the non-thermoelastic transition has been observed from mechanical spectroscopy and differential scanning calorimetry studies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240900,"idioma_id":4,"titulo":"Morphological variations of the three otoliths of some species of the family Loricariidae (Ostariophysi: Siluriformes)","resumen":"Otoliths are three pairs of calcareous structures found in the inner ear of bony fish. In many cases they display a species-specific morphology. The present study describes morphological variations of otoliths, namely lapillus, asteriscus and sagitta, of eleven species belonging to four loricariid subfamilies. Otolith structures that characterize the Loricariidae and some of its subfamilies are presented. The sagitta exhibit a specific morphology that is not found in other siluriform families; it is claviform with a tapered posterior region and a flared anterior one. In the latter, central elevations are observed and the dorsal wings are continuous with lateral expansions named basal wings. Hypoptopomatinae and Loricariinae as well as Hypostominae and Ancistrinae can be grouped by two morphological patterns of the lapillus: An ovoid pattern, in which the lapillae are elongated in its supero-inferior axis and the mond hardly exceed the anterior edge of the otolith and, an oval pattern, where the lapillae are elongated in their antero-posterior axis and the mond always exceeds the anterior edge in an obvious way. The patterns proposed here could be diagnostic of certain subfamilies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240905,"idioma_id":5,"titulo":"Isabell Lorey: La precariedad como concepto político","resumen":"La presente reseña describe los principales lineamientos de la reciente obra de Isabel lLorey, ?Estado de Inseguridad. Gobernar la precariedad?, editada por Traficantes de Sueños y prologada por Judith Butler. El libro indaga en las formas de precariedad y sus implicancias sociales. No se pregunta cómo prevenir y poner fin a la misma, sino lo que busca es comprender cómo somos gobernados específicamente a través de la precarización y cómo nos mantenemos gobernables. Para ello, analiza sus dimensiones y la normalización de lo precario en la fase actual del régimen de acumulación. Finalmente, nos invita a pensar los estados de inseguridad inducidos como posibilidad de movilización política a fin de irrumpir el orden establecido.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240906,"idioma_id":4,"titulo":"N:P:S stoichiometry in grains and physiological attributes associated with grain yield in maize as affected by phosphorus and sulfur nutrition","resumen":"Balanced nutrition is necessary to reduce yield gaps in maize. Simultaneous phosphorus (P) and sulfur (S) deficiencies may be present in soils, so a P +ù S interaction is expected. In maize, yield is closely related to grain number (GN); thus, nutrient deficiencies impacting crop growth during GN formation can consequently impact yields. Grain nutrient concentration may reflect soil supplying capacity, and nutrient stoichiometry in grains can be used as an indirect indicator of nutrient deficiency for a retrospective diagnosis of sites responsive to P or S fertilization. The objectives of this study were to: i) determine maize response to increasing S fertilizer rates and to P addition; ii) analyze the effects of P, S, and their interaction on mechanisms involved in yield determination of maize; and iii) evaluate the effects of P and S shortage on stoichiometric relationships among N, P, and S content in maize grains. Two fertilization experiments were conducted on-farming conditions in 19 sites-year (SY) for analyzing grain yield response to increasing S fertilizer rates (E1), and studying the interaction between P and S fertilization on grain yield and physiological attributes associated with grain yield determination (E2), i.e. CGRCP, IPARCP, RUECP and biomass at R6. Also N (%N), S (%S) and P (%P) concentration in grains were determined. Stoichiometric relationships among N, P and S in both P or S fertilized and unfertilized treatments in all SY were analyzed. Average grain yield response due to S and P addition was ca. 13 and 20%, respectively. Grain yield increased up to S fertilizer rates around 10 kg S haGêÆ1. P addition increased CGRCP by 15GÇô60% in 8 SY while S addition 12GÇô16% in 2 SY. Both, RUECP and IPARCP were positively associated with biomass production. P fertilization increased IPARCP by 4%, but no S effect was observed. Before silking, P addition boosted cumulated radiation by 7%, but after silking no P or S effects were observed. A significant P +ù S interaction was observed for RUECP, since S fertilization increased RUECP by 14% only when P was not added. Independently of P or S shortage, grain N content scaled almost isometrically with grain S content, while N:P and P:S showed allometric relationships. Phosphorus deficiency did not modify N:S, N:P nor P:S stoichiometry. Likewise, S addition did not modify the N:P or N:S stoichiometry. A significant change in the intercept of the P:S relationship was observed in response to fertilization and may be used as a tool for identifying S responsive sites using grain nutrient analysis","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240907,"idioma_id":4,"titulo":"Two new species of Oxysarcodexia Townsend (Diptera: Sarcophagidae) from the Chaco forest ecoregion of South America","resumen":"Two new Neotropical species of the genus Oxysarcodexia Townsend (Diptera: Sarcophagidae) from Chaco ecoregion of Argentina are described, O. berthet, sp. nov. and O. ibera, sp. nov. Both species were recovered from localities in the eastern part of the Chaco forest (Humid Chaco). The descriptions are based on the male external morphology and terminalia. Photographs and SEM images are provided to aid in the identification of the species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240911,"idioma_id":5,"titulo":"Terceras Jornadas de Tecnologías de la Información Geográfica del Sur Argentino.","resumen":"Entreel 24 y 26 de agosto del año 2016, se llevaron a cabo en la ciudad de BahíaBlanca las Terceras Jornadas de Tecnologías de la Información Geográfica delSur Argentino organizadas por el Departamento de Geografía y Turismo de laUniversidad Nacional del Sur. El evento permitió dar continuidad a este tipo deencuentros que se iniciaron en el año 2010, con la premisa de poner enevidencia el creciente uso de las Tecnologías de la Información Geográfica(TIG) en diversos campos del saber y también, construir un espacio en el queprofesionales de diversas disciplinas puedan compartir e intercambiarexperiencias y conocimientos.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; En la búsqueda de fortalecer los vínculos logrados entrelos integrantes de diversas instituciones participantes (universidades,municipios, agencias del INTA, etc.) y&nbsp;propiciar un ámbito adecuado para exponer los trabajos realizados, losobjetivos de las Terceras Jornadas de Tecnologías de la Información Geográficadel Sur Argentino fueron: a) Generar un espacio de intercambio académicomultidisciplinario entre profesionales de áreas temáticas diversas vinculadaspor la utilización de TIG´s y b) Difundir los avances relacionados con laaplicación de TIG´s para estudiar diferentes problemáticas territoriales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240913,"idioma_id":4,"titulo":"Bovine leukemia virus: current perspectives","resumen":"Enzootic bovine leukosis, caused by bovine leukemia virus (BLV), is the most common neoplasm of dairy cattle. Although beef and dairy cattle are susceptible to BLV infection and BLV-associated lymphosarcoma, the disease is more commonly detected in dairy herds, mostly because of the management practices in dairy farms. The pathogenicity of BLV in itsnatural host, the bovine, depends mainly on the resistance\/susceptibility genetics of the animal.The majority of infected cattle are asymptomatic, promoting the extremely high disseminationrate of BLV in many bovine populations. The important productive losses caused by the BLV,added to the health risk of maintaining populations with a high prevalence of infection with aretrovirus, generates the need to implement control measures. Different strategies to controlthe virus have been attempted. The most effective approach is to identify and cull the totalityof infected cattle in the herd. However, this approach is not suitable for herds with high prevalenceof infection. At present, no treatment or vaccine has proven effective for the control ofBLV. Thus far, the genetic selection of resistant animals emerges as a natural strategy for thecontainment of the BLV dissemination. In natural conditions, most of the infected, resistantcattle can control the infection, and therefore do not pass the virus to other animals, graduallydecreasing the prevalence of the herd.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240915,"idioma_id":4,"titulo":"Analysis of triglyceride synthesis unveils a green algal soluble diacylglycerol acyltransferase and provides clues to potential enzymatic components of the chloroplast pathway","resumen":"Background: Microalgal triglyceride (TAG) synthesis has attracted considerable attention. Particular emphasis has been put towards characterizing the algal homologs of the canonical rate-limiting enzymes, diacylglycerol acyltransferase (DGAT) and phospholipid:diacylglycerol acyltransferase (PDAT). Less work has been done to analyze homologs from a phylogenetic perspective. In this work, we used HMMER iterative profiling and phylogenetic and functional analyses to determine the number and sequence characteristics of algal DGAT and PDAT, as well as related sequences that constitute their corresponding superfamilies. We included most algae with available genomes, as well as representative eukaryotic and prokaryotic species. Results: Amongst our main findings, we identified a novel clade of DGAT1-like proteins exclusive to red algae and glaucophyta and a previously uncharacterized subclade of DGAT2 proteins with an unusual number of transmembrane segments. Our analysis also revealed the existence of a novel DGAT exclusive to green algae with moderate similarity to plant soluble DGAT3. The DGAT3 clade shares a most recent ancestor with a group of uncharacterized proteins from cyanobacteria. Subcellular targeting prediction suggests that most green algal DGAT3 proteins are imported to the chloroplast, evidencing that the green algal chloroplast might have a soluble pathway for the de novo synthesis of TAGs. Heterologous expression of C. reinhardtii DGAT3 produces an increase in the accumulation of TAG, as evidenced by thin layer chromatography. Conclusions: Our analysis contributes to advance in the knowledge of complex superfamilies involved in lipid metabolism and provides clues to possible enzymatic players of chloroplast TAG synthesis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240916,"idioma_id":4,"titulo":"Identification and characterization of the major pseudocoelomic proteins of the giant kidney worm, Dioctophyma renale","resumen":"Background: The giant kidney worm, Dioctophyma renale, is a debilitating and potentially lethal parasite that inhabits and destroys, typically, their host?s right kidney, and may also be found in ectopic sites. It is circumglobally distributed, mainly in dogs, and is increasingly regarded as a threat to other domestic animals and humans. There is little information on the parasite?s true incidence, or immune responses to it, and none on its biochemistry and molecular biology. Results: We characterised the soluble proteins of body wall, intestine, gonads and pseudocelomic fluid (PCF) of adult parasites. Two proteins, P17 and P44, dominate the PCF of both male and females. P17 is of 16,622 Da by mass spectrometry, and accounts for the intense red colour of the adult parasites. It may function to carry or scavenge oxygen and be related to the ?nemoglobins? found in other nematode clades. P44 is of 44,460 Da  and was found to associate with fatty acids by thin layer chromatography. Using environment-sensitive fluorescent lipid probes, P44 proved to be a hydrophobic ligand-binding protein with a binding site that is highly apolar, and competitive displacement experiments showed that P44 binds fatty acids. It may therefore have a role in distributing lipids within the parasites and, if also secreted, might influence local inflammatory and tissue responses. N-terminal and internal peptide amino acid sequences of P44 indicate a relationship with a cysteine- and histidine-rich protein of unknown function from Trichinella spiralis. Conclusions: The dominant proteins of D. renale PCF are, like those of large ascaridids, likely to be involved in lipid and oxygen handling, although there is evidence of strong divergence between the two groups.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240917,"idioma_id":4,"titulo":"FABP1 knockdown in human enterocytes impairs proliferation and alters lipid metabolism","resumen":"Fatty Acid-Binding Proteins (FABPs) are abundant intracellular proteins that bind long chain fatty acids (FA) and have been related with inmunometabolic diseases. Intestinal epithelial cells express two isoforms of FABPs: liver FABP (LFABP or FABP1) and intestinal FABP (IFABP or FABP2). They are thought to be associated with intracellular dietary lipid transport and trafficking towards diverse cell fates. But still their specific functions are not well understood.To study FABP1´s functions, we generated an FABP1 knockdown model in Caco-2 cell line by stable antisense cDNA transfection (FABP1as). In these cells FABP1 expression was reduced up to 87%. No compensatory increase in FABP2 was observed, strengthening the idea of differential functions of both isoforms. In differentiated FABP1as cells, apical administration of oleate showed a decrease in its initial uptake rate and in long term incorporation compared with control cells. FABP1 depletion also reduced basolateral oleate secretion. The secreted oleate distribution showed an increase in FA\/triacylglyceride ratio compared to control cells, probably due to FABP1´s role in chylomicron assembly. Interestingly, FABP1as cells exhibited a dramatic decrease in proliferation rate. A reduction in oleate uptake as well as a decrease in its incorporation into the phospholipid fraction was observed in proliferating cells.Overall, our studies indicate that FABP1 is essential for proper lipid metabolism in differentiated enterocytes, particularly concerning fatty acids uptake and its basolateral secretion. Moreover, we show that FABP1 is required for enterocyte proliferation, suggesting that it may contribute to intestinal homeostasis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240918,"idioma_id":4,"titulo":"Can Edaphic Variables Improve DTPA-Based Zinc Diagnosis in Corn?","resumen":"Current zinc (Zn) diagnostic methods for corn (Zea mays L.) are often based on soil DTPA (diethylenetriamine-pentaacetic acid) extractable Zn (DTPA-Zn). However, calibration of the DTPA-Zn test may be influenced by other soil properties such as pH, organic matter (SOM) and available Bray-P (PBray-1). Our objective was to assess the contribution of soil properties to a DTPA-Zn model used to predict corn response to Zn fertilization. We conducted 64 field trials with two Zn-fertilization treatments: with and without Zn fertilization. In all sites, we measured SOM, PBray-1, pH, and DTPA-Zn at 0- to 20-cm depth before sowing. Yield difference between Zn-fertilized and unfertilized treatments (Ydifference) was significant in 33% of the experimental site-years. In responsive site-years, the average Ydifference was 0.98 Mg ha-1 (11.4%). Soil organic matter was the only property that was a significant addition to the DTPA-Zn model for predicting the corn relative yield (Model R2 including SOM = 0.27). However, the improvement was nominal (Partial R2 of SOM = 0.06). Use of DTPA-Zn alone was suitable to discriminate Zn responsiveness among site-years based on the Ydifference by correctly diagnosing 81% of the outcomes. We determined three soil DPTA-Zn ranges with different probability of resulting in a Ydifference greater than zero when fertilized with Zn: high (&lt;0.9 mg kg-1), medium (0.9GÇô1.3 mg kg-1), and low (&gt;1.3 mg kg-1). These soil-test-based Zn recommendations improve the identification of Zn-deficient soils allowing prevention of yield loss from Zn deficiency and more rational use of Zn fertilizers","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240919,"idioma_id":5,"titulo":"Entre ideologias y Practicas. Las configuraciones pedagogicas como precipitado. Aportes a la Educacion Superior","resumen":"RESUMENEstacomunicación expone hallazgos empíricos de la tesis doctoral: RelaciónPedagógica en la Universidad, intersubjetividad y formación. Es impensable larelación pedagógica desde una mirada furtiva que deje escurrir las vicisitudesvinculares, los etéreos anudamientos intersubjetivos. Se rescata la relaciónpedagógica, exponencial e indiscutiblemente asociada a lo vincular, en cuyomarco docente y alumno, protagonistas de la diada pedagógica, son puestos aresguardo, como ?garantía&nbsp; de unaexperiencia exitosa?. Esta aseveración es punto de partida y base deposicionamiento. El objetivo de esta presentación consiste en anudar ideologíay prácticas docentes, accediendo a las configuraciones pedagógicas comoprecipitado, en el marco de la Educación Superior en contextos actuales. Las configuraciones pedagógicas aluden al conjuntode rasgos, cualidades, características etc. que modelan el vínculo pedagógico.Dada su complejidad son superadoras e inclusivas de la práctica y apoyan enun&nbsp; perfil ideológico. La prácticadocente se inscribe a partir del relacionamiento con el saber; en esaencrucijada el docente puede operar como trasmisor o gestor. Las modalidadesideológicas aluden a bagaje de ideas sobre la realidad, sostienenracionalidades varias, se inscriben en actitudes, valores, posiciones y sonportadoras de baluartes narcisistas que sostienen la autoestima docente. Elanálisis de la categoría ideología resulta una herramienta heurística valiosa yfecunda como cimiento de la práctica y precipitante de las configuracionesvinculares, en el contexto pedagógico. La puesta en valor de estas temáticas noes cuestión estéril, ni errática, gravita profundamente en el trayectoformativo hendido por cuestiones, asiduamente banalizadas, losubjetivo\/intersubjetivo, personal\/ vincular. &nbsp;&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240920,"idioma_id":4,"titulo":"The VMC survey XXVII. Young stellar structures in the LMC bar  star-forming complex","resumen":"The star-forming complex in the bar region of the Large Magellanic Cloud is investigated with theVISTA Survey of the Magellanic Clouds. Upper main-sequence stars younger than &#8764;1 Gyr are usedas tracers, which have highly non-uniform and clumpy distributions. They exhibit large amounts ofoverdensities, corresponding to young (.100 Myr) stellar structures inside the complex. Young stellarstructures are identified in a systematic way from the stellar density map as density enhancementsof different significance levels. We find that these structures are organized in a hierarchical mannersuch that larger, lower-density structures contain one or several smaller, higher-density ones. Beyondthe completeness threshold, the young stellar structures follow a power-law size distribution, which isconsistent with a fractal dimension of D2 = 1.5 ± 0.1. They have a power-law mass function of theform n(M )dM &#8733; M &#8722;&#946; dM , with &#946; = 2.0 ± 0.1. Their surface densities, on the other hand, agree withlognormal distributions. All these results support a scenario of hierarchical star formation which hasbeen regulated by turbulence. The temporal evolution of young stellar structures is explored by usingsubsamples of upper main-sequence stars with different magnitude and age ranges. With two-pointcorrelation functions, we quantitively show that while the youngest subsample, with a median age oflog(&#964; \/yr) = 7.2, contains most substructure, progressively older ones are less and less substructured.Specifically, the oldest subsample, with a median age of log(&#964; \/yr) = 8.0, is almost indistinguishablefrom a uniform distribution on spatial scales of 30?300 pc. This suggests that the young stellarstructures are completely dispersed on a timescale of &#8764;100 Myr after their birth. These resultsare consistent with the 30 Doradus complex and the entire Large Magellanic Cloud, suggesting nosignificant environmental effects in the results. We further point out that the fractal dimension maybe method-dependent even for the same sample, as long as the sample has a significant age spread.Subject headings: infrared: stars ? Magellanic Clouds ? stars: formation","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240921,"idioma_id":4,"titulo":"The SSRI fluoxetine exhibits mild effects on the reproductive axis in the cichlid fish Cichlasoma dimerus (Teleostei, Cichliformes)","resumen":"Among the wide variety of pharmaceuticalsreleased into the environment, Fluoxetine (FLX), a selective serotonin reuptakeinhibitor, is one of the most prescribed for the treatment of major depression.It inhibits serotonin (5-HT) reuptake at the presinaptic membrane, increasingserotonergic activity. In vertebrates, including fish, the serotonergic systemis closely related to the Hypothalamic Pituitary Gonadal (HPG) axis whichregulates reproduction. As FLX can act as an endocrine disrupting compound (EDC)by affecting several reproductive parameters in fish, the aim of this study wasto provide an integral assessment of the potential effect of FLX on thereproductive axis of the Neotropical freshwater fish Cichlasoma dimerus. Adult fish were intraperitoneally injected with2 µg g-1 FLX or saline every third day for 15 days. No significantdifferences were found on serotonergic turnover (5-HIAA\/5-HT ratio). Pituitary &#946;LHcontent in FLX injected females was significantly higher than control females;no significant differences were seen for &#946;FSH content. Sexsteroids remained unaltered, both in males and females fish, after FLXtreatment. No plasma vitellogenin was induced in treated males. Somealterations were seen in testes of FLX injected males, such as the presence offoam cells and an acidophilic PAS positive, Alcian-Blue negative secretion inthe lobular lumen. Although there is no clear consensus about the effect ofthis drug on reproductive physiology, these results indicate that FLX is actingas a mild EDC in adults of C. dimerus.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240922,"idioma_id":4,"titulo":"Dynamics of ovarian maturation throughout the reproductive cycle of the neotropical cichlid fish Cichlasoma dimerus (Teleostei, Cichliformes)","resumen":"In this study, we analyzed gene expression profiles, plasma steroids concentrations, and gonadal morphology throughout the reproductive cycle of female Cichlasoma dimerus (Heckel, 1840), a monogamous cichlid fish exhibiting social hierarchies. Fish were analyzed at six phases encompassing their annual cycle, namely resting (during the nonreproductive period), prespawning, 30 h post spawning, 4 days post spawning, 10 days post spawning, and subordinate (during the reproductive period). The histological and histomorphometric analysis showed that C. dimerus exhibits asynchronous ovarian development. Similar to resting females, subordinate females showed low gonadosomatic index, reduced expression levels of vitellogenin (vtgAb), zona pellucida (zpB), gonadal aromatase (cyp19a1A), and low concentrations of plasma sex steroids, thus indicating that social intimidation by dominant conspecifics elicited reproductive arrest. In reproductively active females, a direct positive correlation between plasma estradiol, vtgAb expression, percentage of late vitellogenic oocytes, and gonadosomatic index was observed. These parameters were maximal at the prespawning phase, decreased at 30 h post spawning and 4 days post spawning, and then reached a peak at 10 days post spawning. Our results indicate that female C. dimerus become spawning capable after 10 days post spawning, coincidently with the shortest time interval between successive spawns recorded in captivity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240923,"idioma_id":4,"titulo":"Endocrine disruption of phenanthrene in the protogynous dusky grouper Epinephelus marginatus (Serranidae: Perciformes)","resumen":"The dusky grouper Epinephelus marginatus is a protogynous hermaphrodite fish, that maintains highlevels of plasma steroids as juveniles, as substrates for sex inversion. These fish are exposed to marinepollution from oil spills during cargo handling. Polycyclic aromatic hydrocarbons (PAHs), such as phenanthrene(Phe), are the main crude oil components and are toxic to fish, acting as endocrine disruptors (ED).This is the first study that investigated impacts of Phe as an ED in E. marginatus juveniles. An in vivo sublethalexposure (96 h) to Phe was carried out at two concentrations (0.1 mg\/L and 1 mg\/L); exposure tothe vehicle (ethanol; ETOH) was also performed. Plasma levels of 17b-estradiol (E2), testosterone (T) and11-ketotestosterone (11-KT) were measured by ELISA. Gonads, liver and spleen were processed for histologicalanalysis. In an in vitro bioassay, gonad fragments were incubated with Phe (8.91 mg\/L) orETOH. Steroid levels in the culture media were measured by ELISA. The in vivo exposure to Phe triggeredan increase of the area of the hepatocytes, increased number of melanomacrophagic centers andhemosiderosis in the spleen; ETOH induced similar effects on spleen. E2 and T levels did not change inplasma or in vitro media. In plasma, ETOH decreased 11-KT levels. Phenanthrene sharply reduced 11-KT levels in vitro. Although in vivo bioassay results were not unequivocal owing to ethanol effects, Phemight disrupt steroidogenesis in juvenile grouper, possibly causing dysfunctions during sex changeand gonadal maturity, considering the importance of 11-KT in developing ovaries.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240933,"idioma_id":4,"titulo":"Sperm chemorepulsion, a supplementary mechanism to regulate fertilization","resumen":"Study question: Are human spermatozoa able of chemorepulsive behavior?Summary answer: Capacitated human spermatozoa are able to be chemorepelled by synthetic Progesterone Receptor Ligands (sPRL, known as contraceptives) and zinc (a cation released by the oocyte upon fertilization).What is known already: Moving cells can be oriented towards or against a molecular gradient, processes called chemoattraction and chemorepulsion, respectively, which have been described in unicellular organisms such as amoebas and bacteria, to organismic cells such macrophages and developmental cells. In the case of spermatozoa, chemoattraction may help the finding of an oocyte and has been widely studied in various invertebrate and mammalian species; however, chemorepulsion has not yet been verified in spermatozoa.Study design, size, duration: This is an in vitro study involving human, rabbit and mouse spermatozoa which were used to perform 3 to 30 experiments per treatment. Participants\/materials, setting, methods: Human sperm samples were obtained by masturbation from healthy donors who gave written consent. Only those samples exhibiting normal semen parameters according to current WHO criteria were included in the study. Rabbit spermatozoa were obtained by artificial vagina whereas mice spermatozoa were obtained from epididymis. The Sperm Selection Assay (SSA), originally designed to evaluate sperm chemoattraction towards progesterone (P), and a video-microscopy and computer motion analysis system were used to test sperm chemorepulsion. Additional kinetic parameters were also determined by video-microscopy and computer motion analysis. In some experiments, the level of induced acrosome-reacted spermatozoa was determined. Rabbit mating manipulation was achieved to perform the sperm - oocyte co-incubation assay.  Main results and the role of chance: Sperm accumulation in the well containing 100 pg\/ml of synthetic Progesterone Receptor Ligands (sPRL) was lower than the culture medium negative control (p<0.05). The percentage of sperm persistence against the well containing 100 pg\/ml ulipristal acetate (UPA) (p=0.001), and the percentage of sperm showing a repulsive pattern of movement (a linear trajectory followed by a transitional one after turning against the UPA), were higher than the culture medium negative control (p=0.049). Sperm accumulation was diminished when spermatozoa where exposed to a homogeneous distribution of 100 pg\/ml sPRL combined with a chemotactic gradient of progesterone (P), with respect to the culture medium negative control (p<0.05). These results were reverted when non-capacitated spermatozoa were used to perform the same experimental settings. The accumulation of spermatozoa against 100 pg\/ml sPRL was lower than the culture medium negative control also in rabbits and mice (p<0.05). The relative number of rabbit spermatozoa arriving to the vicinity of the oocyte was diminished under the presence of 100 pg\/ml UPA (p=0.004). Sperm accumulation in the well containing zinc was decreased compared to the culture medium negative control (p<0.05). A homogeneous distribution of zinc combined with a gradient of 10 pM P, was lower than the culture medium negative control (p=0.016). The results were quite reproducible with two different methodologies (accumulation assay and video-microscopy combined with computer motion analysis), in three mammalian species. Limitations, reasons for caution: The experiments were performed in vitro. Even though a quite complete characterization of sperm chemorepulsion was provided, the molecular mechanism that governs sperm repulsion is currently under investigation. Wider implications of the findings: Since the chemorepelled spermatozoa are those physiologically ready to fertilise the oocyte, these findings may have both biological and clinical implications, preventing either polyspermy under natural conditions or fertilisation under pharmacological treatment with sPRL.Study funding\/competing interest(s): The study was financed by the Universidad Nacional de Cordoba (Argentina). The authors declare that they do not have competing financial interests.Trial registration number: N\/A","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240960,"idioma_id":5,"titulo":"La Comunidad Andina de Naciones: una evaluación de sus instituciones a medio siglo de su gestación","resumen":"La integración y cooperación regional entre los Estadosde América Latina ha presentado, en más de seis décadas de experiencia,distintos resultados como se observa en el caso del Mercosur, la Alianza delPacífico, los países centroamericanos y del Caribe. En este sentido, el procesode la Comunidad Andina de Naciones (en adelante, ?CAN?) ha presentado avances yretrocesos idénticos a los anteriores y amerita un análisis actualizado de susórganos e instituciones de modo que permitan, en lo posible, comprender no sólosu estructura y contexto, sino también su desarrollo y proyección al fracaso ouna convergencia superadora.Para lograr el objetivo propuesto, se realizará unasíntesis histórica de la CAN que nos permita advertir cómo fue su proceso de gestaciónpara, luego, continuar con un análisis de sus instituciones y órganos de modoque nos habilite, finalmente, a realizar algunas consideraciones sobre susdesafíos actuales y futuros.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240961,"idioma_id":5,"titulo":"La integridad territorial y la cuestión Malvinas en un caso de defensa del consumidor","resumen":"El Estado posee al territorio como parte de sus elementos y ejerce susoberanía en la totalidad de este. Sin embargo, esta teoría de losinternacionalistas presenta casos que en la práctica tribunalicia requieren deun análisis que transforme instituciones inicialmente pensados para lasrelaciones entre los Estados, en conceptos útiles para la resolución decontroversias domésticas.Este ejercicio resulta pertinente en el caso ?Acción de defensa delconsumidor Juan Enrique Giusti c\/ Telecom Argentina S.A.?, decidido por la SalaIV de la Cámara en lo Civil y Comercial de la Provincia de Salta, el 5 de abrilde 2017, a pesar de tratarse de un asunto domésticamente apto para su estudiodesde el derecho administrativo, la teoría del Estado, el derecho delconsumidor, el derecho constitucional o el derecho internacional público quees, precisamente, la impronta que desarrollaremos a partir del fallo señalado,seleccionando dos aspectos sobresalientes analizables en relación a este: a) laDisposición Transitoria Primera de la Constitución Nacional, determinante paralos argumentos construidos por los magistrados; y, b) el territorio comoelemento del Estado y sus características para el derecho internacionalpúblico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240962,"idioma_id":5,"titulo":"La terminación de los tratados: el caso de Venezuela y el Mercosur","resumen":"El objetivo del presente trabajoes analizar el procedimiento de adhesión de Venezuela al Mercado Común del Sur y sus consecuencias, incluyendo la actualsuspensión de Estado bolivariano, mediante el relevamiento de documentos,noticias y fuentes académicas especializadas. La propuesta incluye un análisisde los posibles efectos jurídicos que prevé el derecho internacional público enel escenario actual, en particular la Convención de Viena sobre el Derecho delos Tratados de 1969, ante la hipótesis que Venezuela pierda su condición deEstado Parte del bloque regional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240964,"idioma_id":4,"titulo":"Improvement of biomass and cyclic lipopeptides production in Bacillus amyloliquefaciens MEP 2 18 by modifying carbon and nitrogen sources and ratios of the culture media","resumen":"Bacillus amyloliquefaciens MEP218 is a native isolate with a broad spectrum ofantifungal activity against plant pathogenic fungi. The ability of strain MEP218 toantagonize phytopathogens is due to the production of cyclic lipopeptides (CLPs). Inthis work, different carbon (C) and nitrogen (N) sources and C to N ratios wereevaluated in order to improve both, biomass and CLPs production by strain MEP218.Among the C and N sources and C to N ratios tested, glucose and NH4NO3 at the Cto N ratio of 10:1 enhanced significantly biomass and CLPs yield. Moreover, CLPsproduced in this medium exhibited higher antibacterial activity against Xanthomonasaxonopodis pv. vesicatoria (Xav) than those obtained in the recommended mediumfor CLPs production. Interestingly, CLPs addition influenced the development of Xavbiofilm on biotic and abiotic surfaces. A comparison of HPLC-chromatograms ofCLPs obtained in the optimized medium versus the ones obtained in therecommended medium showed a notable increase of surfactin in the CLPs obtainedin the optimized medium. Furthermore, two peaks with antibacterial activity againstXav, identified by mass spectrometry analysis as fengycins A and B, were detected inthe CLPs from the strain MEP218, grown in the optimized culture medium. Theresults obtained in this work suggest that changes in C and N sources and C to Nratios affect the yield and type of CLPs produced by B. amyloliquefaciens MEP218.To the best of our knowledge, this is the first study to report the finding of fengycinswith antibacterial activity. CLPs produced by the strain MEP218 are potentialcandidates for controlling bacterial spot disease in tomato and pepper.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240968,"idioma_id":4,"titulo":"Arsenic and trace elements in soil, water, grapevine and onion in J&aacute;chal, Argentina","resumen":"Contamination by trace elements (TE) is an increasing concernworldwide. In some areas, crop production could be limited by the presence of metals andmetalloids, so it is important to determine their concentrations and mobility. The region of J&aacute;chal, province of San Juan, Argentina, has good growing conditions for onion and grapevine production, but their quality and yield are affected by high TE concentration in soils and water. Soils, water,&lt;br \/&gt;grapevine and onion were sampled and TE content determined. In soils elevated As, B, Cr, Hg, and Tl concentrations were detected (506 &plusmn; 46, 149 &plusmn; 3, 2714 &plusmn; 217, 16 &plusmn; 7, and 12 &plusmn; 3 &mu;g g&minus;1, respectively, for maximum values measured), and physicochemical properties of the soil promotes these elements mobility.Water samples had high As, B, Cr, and Fe concentrations (1438 &plusmn; 400, 10,871 &plusmn; 471, 11,516 &plusmn; 2363, and 3071 &plusmn; 257 &mu;g L&minus;1,&lt;br \/&gt;respectively, for maximum values measured) while in onion bulbs and grapevine berries, As, Cr, Cu, and Fe (92 &plusmn; 7 and 171&plusmn;20, 1412&plusmn;18 and 2965&plusmn;32, 17 &plusmn; 3 and 126 &plusmn;88, and 418&plusmn;204 and 377&plusmn;213 &mu;g g&minus;1, respectively, for maximumvaluesmeasured) exceeded the limits for food consumption established by Argentinian law. Correlation analyses indicated that: i) there is a common source of TE in this area, ii) each elements concentration&lt;br \/&gt;in plants is associatedwith different soil variables and different soils depths, and iii) the lack of correlation between soil and water indicates that concentration in water is not constant over the time and\/or there exists a differential accumulation of elements in soils depending on their own properties. Data obtained demonstrate very high concentration of TE in soil, grapevines, and onion plants in J&aacute;chal region, and different remediation techniques are necessary to stabilize and minimize the bioavailability of these elements.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240969,"idioma_id":4,"titulo":"An attempt to replace an ivermectin-resistant Cooperia spp. population by a susceptible one on grazing pastures based on epidemiological principles and refugia management","resumen":"The maintenance of anthelmintic-susceptible parasite refugia to delay the onset of anthelmintic resistance is an almost impossible effort in many grazing livestock production countries given that current refugia consist of already resistant parasites. Rather, efforts could be focused on replacing the resistant parasite refugia by susceptible parasite ones and implementing sustainable parasite control measures from then on. To this purpose, a trial was conducted to attempt to establish a new population of ivermectin-susceptible Cooperia sp. on a beef cattle farm with proven problems of ivermectin-resistant Cooperia. During two consecutive years, 82 (Year 1) and 100 (Year 2) recently weaned and parasite-free heifers were inoculated with 40,000 or 30,000 susceptible Cooperia L3, respectively, at a time when levels of resistant parasite refugia were normally low. The animals were subsequently allowed to graze on the problem pastures during autumn until the end of spring. Levels of parasitism in the animals and on pasture were monitored monthly and animals were treated with levamisole when needed. The combination of parasitological monitoring and local epidemiological knowledge was essential to determine when treatments were to be administered. No clinical signs of gastrointestinal parasitosis in the herd were observed throughout the study and unnecessary treatments were avoided. Faecal egg counts reduction tests (FECRT) and controlled efficacy tests (CET) employing worm counts were carried out at different times throughout the study to determine the clinical efficacy (FECRT) and the absolute efficacy (CET) of ivermectin, respectively. The clinical efficacy of ivermectin increased from an initial 73% to 99.4%, while the absolute efficacy increased from 54.1% to 87.5% after just two animal production cycles. The switch from a resistant parasite population to a susceptible one requires knowledge of parasitological epidemiology, especially in relation to seasonal variations of parasite populations in both the host and in refugia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240970,"idioma_id":4,"titulo":"Bacteria and smoke-water extract improve growth and induce the synthesis of volatile defense mechanisms in Vitis vinifera L.","resumen":"Sustainable agricultural practices have been developed as alternative to the use of agrochemicals, andviticulture is not exempt of that. Plant growth promoting rhizobacteria (PGPR) and smoke water extracts(SW) are environmentally-friendly alternative to those agrochemicals. The aim of this study was toinvestigate the single or combined effects of SW and the PGPR Pseudomonas fluorescens (Pf) and Bacilluslicheniformis (Bl) on the physiology and biochemistry of grapevines plants. After 38 days, single applicationsof SWsolutions and bacterial suspensions increase rooting and root length. Combined treatmentshad a slight positive effect compared to the water control. At the end of 60-days pot trial, grapevinetreated with 1:1000 SWand Pf applied alone showed increases in stem length, leaf area and fresh weightof the roots, shoot and leaves, although not significantly differences from the water control were found.In addition, Pf augmented chlorophyll relative content, all treatments decreased the stomatal conductance(mainly 1:500 SW, Pf and 1:1000 SW þ Bl), as well as lipid peroxidation in roots (mainly in bacterialtreatments), and induced the synthesis of mono and sesquiterpenes in leaves, where the effect wasenhanced in combined treatments. In conclusion, PGPR and SW are effective to improve growth ofV. vinifera cuttings as well as to increase the plants defense mechanisms that may help them to cope withbiotic and abiotic stresses.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240977,"idioma_id":5,"titulo":"Análisis del Consumo Máximo de Oxigeno de Triatletas juveniles de Elite","resumen":"Objetivo: Analizar el VO2max y el umbral ventilatorio de triatletas juveniles argentinos de elite de ambos sexos y compararlos con los registros internacionales.Metodología: Se evaluó a 12 atletas juveniles (7 hombres y 5 mujeres). Todos pertenecientes a la selección argentina. Se evaluó el peso, estatura y se calculó el índice de Masa Corporal (IMC). Se determinó el VO2max , VCO2 utilizando una cinta deslizante y un analizador de gases. Se registró Velocidad de carrera en VT2 y durante el VO2max. Además se estudió la velocidad en competencia.Resultados: El VO2max promedio de los juveniles varones fue de 68.4 ± 4.3 ml\/kg\/min y en las mujeres juveniles de 56.2 ± 3.9 l\/kg\/min.Conclusiones: Se verificó diferencias significativas de VO2max entre ambos sexos en los atletas  argentinos, presentando valores menores aunque cercanos en relación a los niveles internacionales de adultos y juveniles. Estos resultados sugieren que es importante estudiar las variables fisiológicas críticas en la performance de triatletas para poder planificar los entrenamientos de un modo objetivo conociendo las metas de nivel a alcanzar para pertenecer a la elite internacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240978,"idioma_id":5,"titulo":"Valor pronóstico de la frecuencia cardíaca al alta hospitalaria en pacientes con insuficiencia cardíaca aguda.","resumen":"Resumen:El objetivo del presente trabajo es establecer la asociación entre frecuencia cardiaca (FC) al alta, en pacientes internados por insuficiencia cardiaca (IC), en ritmo sinusal y con deterioro de la fracción de eyección ventricular izquierda (FEVI), con eventos a 6 meses del alta.Material y Método: Analisis retrospectivo de pacientes ingresados en nuestra institución (julio 2010 - junio de 2015) con IC, en ritmo sinusal y con FEVI &#706;50%. Se dividió la población en dos grupos según la FC al alta hospitalaria. Se analizaron características basales y eventos combinados a los 6 meses (muerte por cualquier causa o reinternación por IC). Variables discretas: prueba de chi cuadrado, variables continuas: prueba de t Student, análisis multivariado: regresión logística.Resultados: De la población analizada (82 pacientes), Grupo 1 (FC &#8804; 70 lpm): 40 pacientes y Grupo 2 (FC >70 lpm): 52 pacientes. 73% sexo masculino, edad media de 70.49 años (+\/-12.4). Factores de riesgo cardiovascular: hipertensión arterial (75.6%), diabetes mellitus (48.8%) y la dislipemia (42.7%). Ecocardiograma: Grupo 1: FEVI 35.4 (+\/- 7.7) y Grupo 2: 29.7 (+\/- 11.03), p=0.015. Tratamiento al alta: betabloquentes: 96.3; digoxina: 7.3%; vasodilatadores: 84.2; antagonistas mineralocorticoides 47.6% (Sin diferencias). Eventos combinados a los 6 meses (muerte y reinternación): G2 32.7% vs G1 13.3% (p=0.038). Análisis multivariado: FC &#707;70 lpm fue el único predictor de eventos combinados a los 6 meses (p=0.026).Conclusiones: La FC &#8804;70 lpm al alta hospitalaria en pacientes con insuficiencia cardíaca, en ritmo sinusal y con deterioro de la FEVI disminuye la tasa de mortalidad y las reinternaciones por insuficiencia cardíaca.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240980,"idioma_id":4,"titulo":"Beneficial effects of hydroalcoholic extract and flavonoids from Zuccagnia punctata in a rabbit model of vascular dysfunction induced by high cholesterol diet","resumen":"This study evaluated the effects of a Zuccagnia punctata standardized hydroalcoholic extract (ZpE) and three of its major flavonoids [2´, 4´-dihydroxychalcone (DHC), 7-hydroxyflavanone (HF) and 3, 7-dihydroxyflavone (DHF)] on the vascular reactivity of aortic rings with endothelial dysfunction induced by feeding rabbits on a high cholesterol diet. Rabbits were fed with either normal chow (CD) or a diet containing 1% cholesterol (HD) for 5-6-weeks. Isometric contractions were measured. Concentration response curves (CRC) to ZpE (range from 4.10-2 to 4.10 &#956;g GAE\/ml), DHC, DHF or HF (range from 10-9 to 10-4 M) showed concentration-dependent relaxation of arteries pre-contracted with phenylephrine. ZpE (4.10-2, 4.10-1 and 4 &#956;g GAE\/ml), HF (10-9, 10-7, 10-5 M), DHC (10-9 M) and DHF (10-9 M) added to the bath improved acetylcholine affinity. Pre-treatment of arteries with ZpE (4.10-2 &#956;g GAE\/ml) and DHC (10-9 M) reduced phenylephrine-induced contraction. Incubation with the higher dose of ZpE (4&#956;g GAE\/ml) reduced the angiotensin II- maximal contraction (Cmax) acting asa non-competitive antagonist, while DHC and DHF (10-5 M) caused a non-parallelrightward of the angiotensin II-CRC and reduced the Cmax acting as mixedantagonists. ZpE (4.10-2 &#956;g GAE\/ml), DHC and DHF (10-9 M) caused a rightwarddisplacement of angiotensin II- CRC acting as competitive antagonists. In conclusion the present study demonstrated that a ZpE and its major flavonoids had beneficial effects in arteries with vascular dysfunction induced by hypercholesterolemia.Therefore its use as herbal medicine to prevent cardiovascular risks factors may be promising.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240981,"idioma_id":4,"titulo":"Multiobjective Optimization Model for Wind Power Allocation","resumen":"There is an increasing need for the injection to the grid of renewable energy; therefore, to evaluate the optimal location of new renewable generation is an important task. The primary purpose of this work is to develop a multiobjective optimization model that permits finding multiple trade-off solutions for the location of new wind power resources. It is based on the augmented &#1013;-constrained methodology. Two competitive objectives are considered: maximization of preexisting energy injection and maximization of new wind energy injection, both embedded, in the maximization of load supply. The results show that the location of new renewable generation units affects considerably the transmission network flows, the load supply, and the preexisting energy injection. Moreover, there are diverse opportunities to benefit the preexisting generation, contrarily to the expected effect where renewable generation displaces conventional power. The proposed methodology produces a diverse range of equivalent solutions, expanding and enriching the horizon of options and giving flexibility to the decision-making process.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240982,"idioma_id":4,"titulo":"Optimized Complex Power Quality Classifier Using One vs. Rest Support Vector Machine","resumen":"Nowadays, power quality issues are becoming a significant research topic because of the increasing inclusion of very sensitive devices and considerable renewable energy sources. In general, most of the previous power quality classification techniques focused on single power quality events and did not include an optimal feature selection process. This paper presents a classification system that employs Wavelet Transform and the RMS profile to extract the main features of the measured waveforms containing either single or complex disturbances. A data mining process is designed to select the optimal set of features that better describes each disturbance present in the waveform. Support Vector Machine binary classifiers organized in a ?One Vs Rest? architecture are individually optimized to classify single and complex disturbances. The parameters that rule the performance of each binary classifier are also individually adjusted using a grid search algorithm that helps them achieve optimal performance. This specialized process significantly improves the total classification accuracy. Several single and complex disturbances were simulated in order to train and test the algorithm. The results show that the classifier is capable of identifying >99% of single disturbances and >97% of complex disturbances.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240983,"idioma_id":4,"titulo":"Autoscaling Scientific Workflows on the Cloud by Combining On-demand and Spot Instances [Thomson ISI, JCR 2015\/2016=0.348]","resumen":"Autoscaling strategies achieve efficient and cheap executions of scientific workflows running in the cloud by determining appropriate type and amount of virtual machine instances to use while scheduling the tasks\/data . Current strategies only consider on-demand instances ignoring the advantages of a mixed cloud infrastructure comprising also spot instances. Although the latter type of instances are subject to failures and therefore provide an unreliable infrastructure, they potentially offer significant cost and time improvements if used wisely. This paper discusses a novel autoscaling strategy with two features. First, it combines both types of instances to acquire a better cost-performance balance in the infrastructure. And second, it uses heuristic scheduling to deal with the unreliability of spot instances. Simulated experiments based on 4 scientific workflows showed substantial makespan and cost reductions of our strategy when compared with a reference strategy from the state of the art entitled Scaling First. These promising results represent a step towards new and better strategies for workflow autoscaling in the cloud.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240991,"idioma_id":4,"titulo":"Lactobacillus casei BL23 Produces Microvesicles Carrying Proteins That Have Been Associated with Its Probiotic Effect","resumen":"Archaea, bacteria, and eukarya secrete membrane microvesicles (MVs) as a mechanism for intercellular communication. We report the isolation and characterization of MVs from the probiotic strain Lactobacillus casei BL23. MVs were characterized using analytical high performance techniques, DLS, AFM and TEM. Similar to what has been described for other Gram-positive bacteria, MVs were on the nanometric size range (30?50 nm). MVs carried cytoplasmic components such as DNA, RNA and proteins. Using a proteomic approach (LC-MS), we identified a total of 103 proteins; 13 exclusively present in the MVs. The MVs content included cell envelope associated and secretory proteins, heat and cold shock proteins, several metabolic enzymes, proteases, structural components of the ribosome, membrane transporters, cell wall-associated hydrolases and phage related proteins. In particular, we identified proteins described as mediatorsof Lactobacillus? probiotic effects such as p40, p75 and the product of LCABL_31160, annotated as an adhesion protein. The presence of these proteins suggests a role for the MVs in the bacteria-gastrointestinal cells interface. The expression and further encapsulation of proteins into MVs of GRAS (Generally Recognized as Safe) bacteria could represent a scientific novelty, with applications in food, nutraceuticals and clinical therapies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240995,"idioma_id":5,"titulo":"Rubén Darío, Del símbolo a la realidad. Obra selecta (Edición conmemorativa)","resumen":"Reseña bibliográfica del libro Rubén Darío, Del símbolo a la realidad. Obra selecta, Madrid, Real Academia española y Asociación de Academias de la lengua española, 2016, 640 pp.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240996,"idioma_id":4,"titulo":"Optimized Complex Power Disturbance Classifier Using One vs. Rest Support Vector Machines","resumen":"Nowadays, power quality issues are becoming a significant research topic because of the increasing inclusion of very sensitive devices and considerable renewable energy sources.In general, most of the previouspower quality classification techniques focused on single power quality events anddid not include an optimal feature selection process. This paper presents a classification system that employs Wavelet Transform and theRMS profile to extract the main features of the measured waveforms containing either single or complex disturbances. A data mining process is designedto select the optimal set of features that better describes each disturbance present in the waveform. Support Vector Machine binary classifiers organized ina ?One Vs Rest? architecture are individually optimized to classify single and complex disturbances. The parameters that rule the performance of each binary classifier are also individually adjusted using a grid search algorithm thathelpsthem achieve optimal performance.This specialized process significantly improves the total classification accuracy. Several single and complex disturbances were simulated in order to train and test the algorithm.The results showthat the classifier is capable of identifying >99% of single disturbances and >97% of complex disturbances.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":240999,"idioma_id":5,"titulo":"El consumidor internacional","resumen":"El artículo se refiere al consumidor internacional, para lo cual se comienza a definir ese concepto, se explica el fundamento de las políticas de protección del consumidor, cuyos derechos integran los llamados derechos humanos de tercera generación. A continuación, se examinan las normas de fuente convencional y las normas determinantes de jurisdicción y de derecho aplicable contenidas en el Código Civil y Comercial de la Nación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241007,"idioma_id":5,"titulo":"Introducción al Dossier Trabajadoras y trabajadores del cuidado en Argentina","resumen":"No tiene abstract.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241009,"idioma_id":5,"titulo":"LA INNOVACIÓN  EN EL ÁREA COMERCIAL A TRAVÉS  DE  LA GESTIÓN  DE LAS EXPERIENCIAS","resumen":"El presente ensayo tiene como objetivo presentar una propuesta para la gestión del área comercial a través de la elaboración y la generación de experiencias con la creación de valor en los mercados que las organizaciones sirven. Se hace un análisis de la función de la gerencia comercial describiendo el tipo de cultura de innovación que prima en las empresas que gestionan las experiencias. Se plantean las estructuras ambidiestras en las organizaciones, y la influencia e impacto de las funciones de exploración en la gerencia comercial cuando crean y gestionan distintos tipos de experiencias. Se incluye la temática dentro del modelo de negocio. Se describen las capacidades dinámicas necesarias de las gerencias comerciales que gestionan experiencias. Observamos la importancia del análisis y gestión de las emociones en la cocreación de valor. Se aportan nuevos tipos de experiencias híbridas aplicadas en el mundo por importantes empresas. Se presentan los resultados de la primera investigación sobre experiencias del visitante a los museos argentinos y una descripción del tipo de comprador llamado 'experiencial' de la industria del retail latinoamericana.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241025,"idioma_id":4,"titulo":"Skin penetration and UV-damage prevention by nanoberries","resumen":"SummaryBackgroundEthanolic extract from blueberry (Vaccinium myrtillus) is rich in anthocyanins and thus exhibits antioxidant activity. On the other hand, ultradeformable liposomes are capable of penetrating to the impermeable barrier of skin. Nanoberries are ultradeformable liposomes carrying blueberry extract.ObjectivesIn this study, their capacity to penetrate the stratum corneum and photodamage prevention were tested, with the aim of developing a topical formulation for skin protection from environmental damage.MethodsNanoberries were prepared by lipid film resuspension with ethanolic extract from blueberry, followed by sonication and incorporation to a gel. Size, zeta potential, deformability, rheology, and viscoelasticity were determined. Toxicity was assessed in vivo in zebrafish model, while in vitro cytotoxicity assay was performed on HaCaT and HEK-293T cell lines. Skin penetration was evaluated with the Saarbrücken penetration model followed by tape stripping, cryosection, or optical sectioning. UV-damage protection and photoprotection were determined by ad hoc methods with UVA, UVB, and UVC radiation on HaCaT cells. Wound assay was performed on HaCaT cells.ResultsNanoberries of about 100 nm, with differential elastic properties, did penetrate the stratum corneum, with low toxicity. When HaCaT cells were exposed to UV radiation in the presence of nanoberries, their viability was maintained.ConclusionsNanoberries could be effective to protect the skin from sun photodamage.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241029,"idioma_id":4,"titulo":"Thymol feed supplementation in quail alters the percentages of nutritionally relevant egg yolk fatty acids: Effects throughout incubation","resumen":"BACKGROUND: Polyunsaturated fatty acids (PUFA) are crucial components of egg yolk and particularly prone to oxidative damage, generating losses of nutrients for embryonic development and influencing the quality of eggs for human consumption. The aim of this study was to evaluate whether dietary thymol (a natural antioxidant) is related to changes in quail egg yolk total (T), triglyceride (TG) and phospholipid (PL) fatty acid composition at different stages of embryo development. Thus female Japanese quail (100days of age) were assigned to one of two dietary treatments (12 individuals each): CON (basal diet) or THY (0.0016mol thymol day-1 per bird). After 2 weeks of supplementation, eggs were incubated and samples were obtained at 0, 4 and 16 days of embryonic development. RESULTS: In 0 day THY eggs, &#945;-linolenic acid and n-3 PUFA in T and TG, docosahexaenoic acid and PUFA in T and arachidonic acid in TG were increased, while saturated fatty acids (SFA) in T were reduced. From 4 days on, PUFA, n-3 PUFA and SFA from T and TG in THY eggs were found to be similar to those of CON eggs. The changes in PL throughout incubation were similar in both dietary treatments. CONCLUSION: Thymol would provide the embryo with PUFA for synthesis\/deposition in membranes and\/or assign to supply energy. Additionally, thymol supplementation would be advisable for the production of healthier table eggs.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241030,"idioma_id":4,"titulo":"Volatile organic compounds from the interaction between Fusarium verticillioides and maize kernels as a natural repellents of Sitophilus zeamais","resumen":"Maize kernels are exposed to Sitophilus zeamais attack and Fusarium verticillioides infestation duringstorage, which can result in product deterioration and economic losses. The objective of this study was toevaluate the involvement of the Volatile Organic Compounds (VOCs) emitted by the fungi-corn system ingrain-insect interactions. Volatiles emitted by healthy maize kernels were different from those emittedby fungal infected kernels, with the latter being enriched by alcohols, ketones and sesquiterpenes, whichwere considered early indicators of fungal contamination. The results demonstrated that the kernelsexposed to the fungal VOCs and their pure compounds (1-octen-3-ol and 3-octanol) were less attractiveand less damaged by S. zeamais than controls. In addition to compound adsorption, other processes mayhave caused the protective effect of exposed kernels against insect damage. This is the first contributionof the role of the fungal volatiles on the behavior of S. zeamais, and could provide an importantcontribution to the conservation of stored grains and pest management and an early indicator of fungalcontamination.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241033,"idioma_id":4,"titulo":"Circular cylinder drag reduction by three-electrode plasma symmetric forcing","resumen":"This study reports an efficient reduction of the drag exerted by a flow on a cylinder when the former is forced with a plasma actuator. A three-electrode plasma device (TED) disposed on the surface of the body is considered, and the effect of the actuation frequency and amplitude is studied. Particle image velocimetry (PIV) measurements provided a detailed information that was processed to obtain the time-averaged drag force and to compare the performances of TED actuator and the canonical dielectric discharge barrier actuator. For the Reynolds number considered (Re = 5500), excitations with the TED actuator were more efficient, achieving drag reductions that attained values close to 40% with high net energy savings. The reduction of coherent structures using the instantaneous vorticity fields and a clustering technique allowed us to gain insight into the physical mechanisms involved in these phenomena. This highlights that the symmetrical forcing of the wake flow at its resonant frequency with the TED promotes symmetrical vorticity patterns which favor drag reductions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241038,"idioma_id":5,"titulo":"Militancia y academia: una genealogía fronteriza. Estudios feministas, de género y mujeres en Mendoza","resumen":"Este escrito mapea las condiciones de emergencia de los estudios feministas\/ de género y mujeres en tierras cuyanas desde sus inicios hasta alcanzar una frágil institucionalidad. Apela a la noción degenealogía\/s de mujeres y feministas como herramienta analítica y parte de la conjetura de que existeuna relación entre ideas y condiciones materiales de existencia, entre activismo de mujeres y estudiosde mujeres, feministas y de género. La metodología consiste en revisión bibliográfica y documental yrecolección de evidencia empírica. El trabajo describe las tensiones entre academia y activismofeminista, y señala algunos obstáculos en la institucionalización de los mencionados estudios.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241045,"idioma_id":4,"titulo":"Insights on the history of the scorched mussel Brachidontes rodriguezii (Bivalvia: Mytilidae) in the Southwest Atlantic: a geometric morphometrics perspective","resumen":"Some authors support the idea that an important part of the Miocene marine mollusc fauna is still represented in the Argentinean Province. The fossil mollusc Brachidontes lepida (Philippi) is considered a subspecies of the extant B. rodriguezii (d&#712;Orbigny), a taxon currently present in the Argentinean Biogeographic Province. The aim of this study is to investigate the shell shape relationship between B. lepida and B. rodriguezii using geometric morphometrics. Samples of B. rodriguezii (n = 63) from four localities distributed in Uruguay and Argentina, of B. lepida from the Paraná Formation (n = 26) and of two other extant Brachidontinae present in the region were included in this study. Canonical variate analyses showed that extant species differed in shell shape, with the discriminant function properly allocating 93% of the individuals to their respective species. Using the extant discriminant function, approximate 92%of B. lepida individuals were allocated to B. rodriguezii. This result suggests that B. lepida is more similar in shell shape to B. rodriguezii than to the other extant species present in the region. Considering the material from the Pliocene of Cerro Laciar and from the Pleistocene deposits of Buenos Aires and Bustamante, the presence of B. rodriguezii from the Late Miocene in the warm temperate region is discussed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241046,"idioma_id":5,"titulo":"Comparación de la fertilidad del semen fresco o congelado e intervalos de tiempo a la inseminación en protocolos de sincronización del celo y ovulación en bovinos","resumen":"La criopreservación permite el almacenamiento del semen a largo plazo. Sin embargo, esto conduce al daño del esperma que puede dar lugar a la pérdida completa de la viabilidad o a cambios que posiblemente disminuyen la funcionalidad del mismo. El semen fresco no está expuesto a factores de estrés y dar como resultado una vida más larga en el tracto reproductivo femenino, aumentando así el rango del momento de la inseminación sin afectar la fertilidad. El objetivo de este estudio fue comparar la fertilidad de semen fresco y congelado al variar el intervalo de tiempo entre la retiro de CIDR y la IA usando el protocolo de 7 días de CO-Synch + CIDR para sincronizar el momento de celo. Dentro del grupo de edad, vacas cruzas (n = 389) fueron asignadas aleatoriamente a la inseminación a 36 o 60 h después del retiro del CIDR con semen fresco o congelado (36L, 60L, 36F y 60F) de uno de dos toros A. Angus. Se monitoreó la actividad estral de las vacas desde el retiro del CIDR hasta 60 h después. Las vacas que no mostraron celo recibieron GnRH (100 &#956;g, i.m.), y se tomó una muestra de sangre para análisis de la concentración de estradiol. No hubo diferencias en las tasas de preñez cuando se utilizó semen fresco o congelado (53% y 52%), pero las vacas inseminadas a las 60 h tuvieron una tasa mayor de preñez (P que presentaron celo y se inseminaron a las 60 h después del retiro del CIDR tuvieron mayor preñez en comparación con las vacas que no presentaron celo. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241049,"idioma_id":4,"titulo":"Detection of Lateral Borders on Unmarked Rural Roads","resumen":"This work presents a method to detect roads in rural conditions, considering gravel or stabilized roads. The main features of this type of ways are based on they do not have lanes and either lateral or central delimitations. This type of road is common in several countries that, for their infrastructure road, still have a large percentage considered as belonging to red earth without paving or delineating. In order to detect the edges of the paths, this work proposes ananalysis strategy based on channel selection on HIS color map representation. The selection automatically allows detecting the channel which brings better information. A convolution filter sequence combined with an adaptive HoughTransform is then applied to detect of curves in the way","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241051,"idioma_id":4,"titulo":"Trends in European forest policy research","resumen":"As a scientific enterprise, forest policy research has a long tradition in Europe (Arts 2012, Kleinschmit et al. 2016), especially in German-speaking countries and their forest research organisations in Austria, Germany, and Switzerland. As a result, a vibrant network of forest policy researchers and research organisations evolved over the past 5 decades. This network?s annual meetings are held in German language and are referred to as ?Forstpolitiktreffen? or ?Forstpolitikertreffen?, with the 49th convention held at the Technical University in Zvolen, Slovakia in April 2017.Over the past years, many important forest policy issues have strongly emerged in many countries. As a consequence, also Scandinavian countries started capitalising on systematic forest policy research for tackling timely questions (Kleinschmit et al 2012). A key achievement in this respect was the establishment of the vibrant Nordic Network for Forest Policy Science1, bringing together forest policy researchers from multiple Nordic research organisations every other year in English language.In 2016 both networks joined forces for promoting international forest policy research cooperation based on high scientific standards. Held in Hann. Münden, Germany in March 2016, the 1st International Forest Policy Meeting brought together those two established research networks.2 This key event was jointly organised by the Chair of Forest and Nature Conservation Policy of Göttingen University and the Southern Swedish Forest Research Centre of the Swedish University of Agricultural Sciences (SLU).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241058,"idioma_id":5,"titulo":"La tormentosa relaci&oacute;n entre las grasas y el desarrollo de la diabetes mellitus de tipo 2: actualizado. Parte 1","resumen":"A review is presented on a functional relationship between fat and carbohydrate metabolism and inter-dependence from the traditional concepts of glucose-fatty acids cycle (Randle), and from the insulin resistance portal hypothesis up to the new aspects on brown and beige adipocytes. Emphasis is placed on the normal function of an endocrine pattern, in which its malfunction is the key in the pathophysiology of these conditions: the adipoinsular axis, with a functional link with the hypothalamic-pituitary-adrenal axis, which involves 2adipogenic hormones (insulin and glucocorticoid). This has an influence on the development of omental peri-visceral fat, with severe metabolic consequences. A discussion is also presented on the concept of ectopic fat on non-adipose tissues that results in the incapacity of fatty tissue for storing lipids and the considerations about the endocrine activity of adipocyte producing substances that influence several mechanisms that could result in insulin resistance (leptin, adiponectin, TNF-&#945;, resistin, etc.). New aspects are considered regarding the decrease in the oxidative capacity in the mitochondrial respiratory chain, and the re-birth of the concept of de novo lipogenesis that increases the storing of intra-cellular fat. In non-adipose tissues there are small intra-cellular fat quantities for essential functions, but lipid overloading leads to cell dysfunction (lipo-toxicity) and death (lipo-apoptosis). The stormy relationship between fat and Langerhans? Islets goes beyond the functional effort as consequence of peripheral insulin-resistance and the pancreatic beta cell suffers a direct lipid (or derivatives) functional effect. Without insulin deficiency diabetes does not appear.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241059,"idioma_id":5,"titulo":"Insulin resistance and Gestational Hypertension: A Preliminary Study in a small population of La Plata Municipality (MULP)","resumen":"Pregnant women with impaired insulin sensitivity are at risk for developing hypertensive disorders. By using a cut-off at 2.64 of the homeostasis model assessment (HOMA-IR) in basal condition (HOMA-0), we split our population study (n = 154 pregnant women) into two groups: 1) with basal HOMA-0 &lt; 2.64 (non-insulinresistant; n = 113) and 2) with basal HOMA-0 &gt; 2.64 (insulinresistant; n = 41). We analyzed glucose and insulin circulating levels throughout a 2-h oral 75 g glucose tolerance test (OGTT). The relationship between several parameters related to insulinresistance and the prevalence of pregnancy-induced hypertensive disorders was analyzed. Pregnant women (on week 24-28) were submitted to an OGTT, and glucose and insulin plasma concentrations were measured throughout the test. These peripheral metabolites levels and, the values of the HOMA-IR and the glucose to insulin ratio (G:I) were analyzed. Anthropometric parameters and pregnancy outcome were recorded. Women with HOMA-0 &gt; 2.64 but normal fasting glycemia showed higher insulinemias, G:I values and HOMA-IR values at both times of the OGTT. The later women were at greater risk for developing late pregnancy-induced hypertension compared to women with HOMA-0 &lt; 2.64.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241060,"idioma_id":4,"titulo":"Taxonomic changes of some neotropical species of Arctiini Leach (Lepidoptera: Erebidae: Arctiinae)","resumen":"Arctiini (Lepidoptera, Erebidae, Arctiinae) is the most speciose tribe of tiger moths. In this study, the taxonomy of some Neotropical species of this tribe is reviewed based on habitus and, in some cases, genitalia of type specimens. Lectotypes are designated for two names. Four new combinations are proposed: Agaraea sericeum (Zerny, 1931) comb. n., Biturix nigrostriata (Rothschild, 1909) comb. n., Carales fasciatus (Rothschild, 1909) comb. n. and Opharus pallida (Dognin,1910) comb. n. Six new synonymies are proposed: Agaraea nigrotuberculata Bryk, 1953 (=Agaraea klagesi (Rothschild, 1909)), Opharus ochracea Joicey & Talbot, 1918 and Pelochyta fergusoni Watson & Goodger, 1986 (=Opharus pallida(Dognin, 1910)), Melese flavescens Joicey & Talbot, 1918 (=Melese paranensis Dognin, 1911), Leucanopsis infucata (Berg, 1882) (=Pareuchaetes aurata aurata (Butler, 1875)) and Tessellota pura Breyer, 1957 (=Tessellota cancellata(Burmeister, 1878)). Moreover, Opharus ochracea Joicey & Talbot, 1918 comb. rev. is returned to the original genus. For each rearrangement, both remarks and information about type specimens are provided.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241062,"idioma_id":7,"titulo":"Infanzia avvelenata. Un dibattito in corso su infanzia, salute e agrochimici in Argentina. Un colloquio con Raúl Horacio Lucero","resumen":"El nexo entre agroquímicos y salud constituye un tópico de indudable relevancia. En general, las discusiones transitan por cuestiones vinculadas con la utilidad de estos productos, su necesidad y su peligrosidad. Pero los argumentos se dividen, y en tanto continúan emergiendo problemáticas de salud pública vinculadas, el debate se enfrasca en la cualidad cancerígena (o no) de los productos, y su mala utilización.  Pero la discusión está lejos de ser saldada. La atención ha sido subterránea en contraposición a la utilización masiva de estos productos en diversas latitudes, especialmente en zonas propensas a cultivos transgénicos, con pocos o nulos mecanismos de regulación sobre su aplicación. Argentina no ha sido una excepción. Por otro lado, aunque los estudios científicos que abordaron la problemática no fueron escasos, los hallazgos muchas veces fueron recibidos con actitudes ambivalentes, entre la cautela y el escepticismo.En este cuadro general, las pinceladas de la realidad argentina aportan densidad a la cuestión. Si hasta el momento se habían mantenido en las penumbras en la que suelen permanecer los problemas de las periferias, poco a poco, la eufonía de las voces dispersas se agrupó en un corpus común de experiencias y reclamos. Los escenarios cambiaban, pero una variable se mantenía: la niñez se revelaba directamente afectada, de modos múltiples. Así pues, se corría la voz de que niños eran utilizados como banderas humanas en las fumigaciones; docentes denunciaban pulverizaciones con productos tóxicos sobre los niños y niñas de las escuelas rurales lindantes a campos sembrados; madres y padres exponían la muerte de sus pequeños, desnudando el contacto cotidiano con plaguicidas; mujeres señalaban abortos espontáneos y el fallecimiento de sus hijos recién nacidos, y lo relacionaban a la exposición a productos tóxicos durante el embarazo; médicos pediatras confirmaban un incremento de malformaciones y deficiencias en bebés expuestos durante el período de su gestación.  Por eso, pensar en violencia hacia la infancia también es pensar en silencios cómplices, en la invisibilización de un problema que la golpea directamente (¿no está, acaso, la niñez rural frecuentemente escondida del ojo público?), vulnerando sus garantías y derechos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241064,"idioma_id":5,"titulo":"Una mirada global sobre la influencia de los patrones alimentarios en las enfermedades cardiovasculares","resumen":"Antecedentes: lasenfermedades cardiovasculares (ECV) constituyen la primera causa de muerte anivel global. Si bien alimentos y nutrientes han sido relacionados a lapromoción o prevención de ECV, analizar los componentes dietarios en formaaislada genera resultados parciales y descontextualizados. Objetivo: analizar el concepto y surgimiento delpatrón alimentario (PA) y la evidencia científica sobre su influencia en la ECV.Materiales y métodos: se realizó una búsqueda sistemática depublicaciones en bases de datos electrónicas MEDLINE, EMBASE Lilacs y Scielo. Se incluyeron aquellosartículos que contenían las palabras claves o una combinación de ellas, durante2000-2016.&nbsp; Resultados yconclusiones: independientementede la región geográfica estudiada, un PAsaludable, prudente o mediterráneo, rico en frutas, verduras, granos enteros,legumbres y pescado, se asoció a menor riesgo de ECV, mientras que un PAoccidentalizado o de alimentos procesados, abundante en carnes rojas yprocesadas, granos refinados, frituras y dulces se correlacionó positivamentecon mayor riesgo de mortalidad por ECV, infarto agudo de miocardio, accidentecerebrovascular y cardiopatías isquémicas. Elanálisis de PA constituye una herramienta eficaz para formularrecomendaciones alimentarias acordes a la cultura alimentaria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241065,"idioma_id":4,"titulo":"Story Genres in SFL: A More Flexible Taxonomy. Extrapolating a Taxonomy of Story Genres in Spanish to Story Genres in English","resumen":"The purpose of this article is: (i) to highlight the importance of making the generic structure of the story genres proposed by Plum (2004) and Martin and Rose (2008) more flexible within the Systemic Functional Framework (SFL); (ii) to take up a taxonomy proposed for story genres in Spanish (Salmaso 2009, 2010 a, 2010 b, 2012 a , 2014) which grants more flexibility to the generic structure of the five genres of the narrative family (?recounts?, ?narratives?, ?anecdotes?, ?exempla? and ?observations?) (Plum 2004, Martin and Rose 2008); (iii) to engage in a comparative study of the generic structure of one of the story genres: ?anecdote?.To this end, nine instances of ?anecdotes? were analyzed. All of the ?anecdotes? are written by native speakers of English belonging to different age and gender groups but with similar educational backgrounds (higher education). The examples are analyzed following Salmaso (2010, 2014) and comparisons are drawn between some aspects of the analysis presented herein with the analyses done following Plum?s (2004) and Martin and Rose?s (2008) taxonomies. Results show that it is possible to extrapolate the taxonomy of story genres in Spanish to English, in particular with respect to the genre ?anecdote? which is the focus of this article. Furthermore, this taxonomy enriches the analysis of ?anecdotes? and may be simpler and clearer for applied purposes, such as teaching.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241078,"idioma_id":5,"titulo":"Relaciones entre formación disciplinar, concepciones sobre el aprendizaje y uso de estrategias metacognitivas en estudiantes universitarios de profesorado","resumen":"Detrás de las acciones y estrategias de las personas para aprender o enseñar, existe un cuerpo teórico no explícito, que se configura a partir de un conjunto de supuestos coherentes o incoherentes entre sí, en función de la relación que exista entre lo que el sujeto dice y lo que hace. Estas representaciones implícitas surgen no sólo de la educación formal recibida, sino de la propia historia educativa de cada sujeto y, en el caso de los docentes, orientan de un modo u otro su práctica, tal como lo indican numerosas investigaciones sobre el tema. En este trabajo se analizan las concepciones sobre el aprendizaje y la utilización de estrategias metacognitivas de dos grupos de estudiantes universitarios de profesorado, provenientes de distintas áreas disciplinares: ciencias humanas y ciencias exactas.  Los resultados muestran dependencia de las concepciones de aprendizaje con respecto al dominio de formación disciplinar, situación que se da sólo parcialmente en el caso de la utilización de estrategias metacognitivas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241080,"idioma_id":5,"titulo":"Evaluación de colágeno tipo I en dos razas ovinas a partir de muestras de musculo gluteo medio obtenidas in vivo","resumen":"La terneza es el factor de calidad de la carne más importante y más variable.Tradicionalmente, en las investigaciones para evaluar la terneza de la carne bovina se utilizan ya sea la cuchilla o guillotina de Warner-Bratzler, que mide la fuerza (resistencia) de corte del músculo estudiado, o paneles de catadores. Sin embargo, estos análisis insumen mucho tiempo, dinero y se realizan postmortem. Al igual que los otros parámetros que definen la calidad de la carne, la textura y terneza dependen de numerosos factores relacionados con la producción y el manejo previo y posterior al sacrificio. El objetivo del presente trabajo fue evaluar la cantidad de colágeno intramuscular de tipo I en muestras de músculo Glúteo medio (músculo locomotor) obtenidas in vivo, en dos razas de la especie ovina, Texel y Criolla. Se empleó una muestra aleatoria de 10 animales de 2 años de edad de cada raza, utilizando la técnicahistológica de Picrosirius-red modificada para obtener la cantidad de colágenointramuscular de tipo I. En el músculo Glúteo medio en ovejas de dos años de edad, nose encontraron diferencias entre las razas Texel y Criolla en cuanto a las fibras colágenas(colágeno tipo I), tampoco se detectó correlación entre el peso y las fibras, siendo máspesadas las Texel.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241081,"idioma_id":5,"titulo":"Evaluación de colágeno tipo I en dos razas ovinas a partir de muestras de músculo glúteo medio obtenidas in vivo","resumen":"El objetivo del presente trabajo fue evaluar la cantidad de colágeno intramuscular de tipo I en muestras de músculo Glúteo medio y Dorsal largo, obtenidas ?in vivo?, en dos razas ovinas: Texel y Criolla. Se empleó una muestra aleatoria de 10 animales de 2 años de edad de cada raza utilizando la técnica histológica de Picrosirius-red modificada para obtener la cantidad de colágeno intramuscular de tipo I.  Todos los animales fueron criados y alimentados sobre una pastura natural  en el establecimiento ?Santa Isabel?, de la localidad de 25 de Mayo, Provincia de Buenos Aires. En el momento de tomar las muestras, las ovejas fueron pesadas mediante una balanza mecánica, luego de haber estado 12hs en ayuno. Para el análisis de las variables obtenidas, cantidad (promedio) de fibras colágenas y peso de los ovinos, se emplearon análisis estadísticos exploratorios e inferenciales. El análisis exploratorio incluyó el Análisis de Componentes Principales para contemplar las correlaciones entre las mediciones realizadas sobre un mismo animal. El análisis inferencial contempló Análisis de Correlaciones y Análisis de Varianza, previo análisis de los supuestos.  El procesamiento de los datos se realizó por medio del software InfoStat. En todos los casos se trabajó con un nivel de significación del 5%. Con relación al peso de los animales de ovejas Texel y Criolla podemos decir que existen diferencias entre ambas, siendo animales más pesados las ovejas Texel (valor-p <0,0001). El análisis de varianza no detectó diferencia entre ambas razas para las fibras de colágeno tipo I del músculo Glúteo medio y Dorsal largo (valor-p =  0,3706; 0,1658) respectivamente. En el músculo Glúteo medio y Dorsal largo, en  ovejas de dos años de edad, no se encontraron diferencias entre las razas Texel y Criolla en cuanto a las fibras colágenas (colágeno tipo I), tampoco se detectó correlación entre el peso y las fibras, siendo más pesadas las Texel.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241082,"idioma_id":4,"titulo":"Dicistroviridae : A new viral purification technique","resumen":"The family Dicistroviridae comprises three genera and about twenty species of RNAvirus, most of them with health or agricultural importance. The Triatoma virus (TrV) is the only entomopathogenic virus identified in triatomine bugs up to the present. TrV replicates within the intestinal epithelial cells, causing high mortality rate and delayed development of the molt of these bugs. TrV has been proposed as a biological control agent for vectors of Chagas disease. Viral particles were purified from feces of 1, 5 and 10 insects from an experimental colony of Triatoma infestans infected with TrV. Viral concentration and infectivity were corroborated using polyacrylamide gels and RT-PCR, respectively. In this work we report a method of viral purification that allows to reduce necessary reagents and time, using a very small amount of fecal matter.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241088,"idioma_id":5,"titulo":"La vivienda y los adultos mayores","resumen":"- La vivienda se ha definido como el ámbito en el cual toda persona se desarrolla como tal; en el orden jurídico, es el espacio que garantiza la efectividad de los derechos de la personalidad y, en el plano moral, es el centro de la esfera de su intimidad.- El derecho humano a la vivienda es contemplado como ?el derecho de todo hombre, mujer, joven y niño a acceder y mantener un hogar y una comunidad en que puedan vivir en paz y dignidad.?- Consideramos adultos mayores a las personas que se encuentran en el  tramo de la vida con sus específicos requerimientos y el modo en que la persona se instala frente a ella condicionado por múltiples factores, como la salud, la educación  personal, familiar o económica, sin establecer o prefijar una edad precisa.- El adulto mayor es sujeto activo de los mismos derechos humanos que todas las personas, con la peculiar situación de vulnerabilidad que proviene de su debilidad física, jurídica, afectiva, económica, moral, en que se encuentran.- La vivienda es unos de los elementos que condicionan la calidad de vida de las personas adultas mayores. La adecuación habitacional implica reconocer la diversidad de necesidades y preferencias de las personas adultas mayores, exige que la vivienda deba ser adaptada para satisfacer las necesidades de autonomía e independencia de los ancianos. De esta forma, la vivienda puede ser enfocada como una herramienta de fomento de la salud y de la calidad de vida de las personas adultas mayores.- La protección de la vivienda de los adultos mayores en el ejercicio de su autonomía personal, comprende el estudio de las siguientes instituciones: a) la vivienda, b) atribución del uso de la vivienda familiar, c) derecho real de habitación del cónyuge\/conviviente supérstite, d) indivisión de la vivienda por oposición del cónyuge supérstite, e) renta vitalicia ?usufructo, f) inembargabilidad de la vivienda hipotecada por el Banco Hipotecario.- La afectación de la vivienda es una institución de suma importancia debido a que las personas adultas mayores, en pleno ejercicio de la autonomía de la voluntad, pueden solicitar la tutela de su vivienda y extender esta protección a su cónyuge, conviviente u otro pariente para después de su muerte.- La atribución de la vivienda familiar implica conceder a un cónyuge, conviviente o familiar el uso del inmueble en  el cual se desarrolló la vida familiar, y para decidir la preferencia entre uno de ellos, se establecen pautas de tipo objetivo, relacionadas con la situación de vulnerabilidad o mayor necesidad como son las personas mayores.- La atribución de la vivienda familiar al ex conviviente tiene su fundamento en la  protección del conviviente que se encuentre más débil al momento de la ruptura de la unión convivencial.- La atribución preferencial de la vivienda familiar o derecho a la locación de la vivienda familiar al cónyuge supérstite o heredero  contribuye al fortalecimiento de la autonomía, dignidad e independencia de las personas adultas mayores al poder solicitar permanecer en el hogar que compartiera con sus más profundos afectos.- Derecho real de habitación del cónyuge supérstite  coadyuva a un mejor amparo de las personas que enviudan en esta etapa de la vida, puesto que juntamente con la protección habitacional, cobra una gran relevancia afectiva el último hogar que se compartió con el ser querido.- Derecho real de habitación del conviviente supérstitepodrá invocarse en los casos en que, por su situación de vulnerabilidad económica, el conviviente supérstite no posea vivienda propia ni bienes que le permitan acceder a la misma. - La indivisión de la vivienda por oposición del cónyuge supérstite es la propia persona adulta mayor quien autónomamente procura para sí la protección de la vivienda luego de acaecida la muerte de su cónyuge.- La protección de la vivienda de los adultos mayores adquiere connotaciones especiales en la esta etapa de la vida ya que tienen además de un significado material, un significado sociológico y social.- El derecho a poder permanecer en el hogar que compartiera con su cónyuge, conviviente fallecido o familiares contribuye al fortalecimiento de la autonomía, dignidad e independencia de las personas adultas mayores, a la vez que colabora con la efectivización de los derechos a la salud, a la intimidad, a la calidad de vida, entre otros.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241092,"idioma_id":5,"titulo":"La construcción del fado y del tango como símbolos nacionales en las primeras películas sonoras de Portugal (A Severa) y de Argentina (Tango!)","resumen":"El propósito de este artículo es analizar la imagen del tango y del fado construida por Tango! y A Severa, los primeros filmes sonoros de Argentina y de Portugal, respectivamente, y sopesar las coincidencias entre ambos procesos. En una apuesta nacionalista, estas dos cintas canalizan el asombro colectivo frente a la creación espontánea de estas dos músicas, pronto devenidas símbolos nacionales en sus correspondientes países, y fomentan ciertos mitos relacionados con sus historias y sus universos metafóricos. Postulamos que ambas producciones coinciden en realizar la mitificación del tango y del fado sobre la base de cuatro ejes: lo femenino activo, la transgresión, el traslado y la verticalidad.'Meridional. Revista chilena de estudios latinoamericanos' es una publicación con referato, indizada en Dialnet, DOAJ, Latindex, Gale, PRISMA, ERIH Plus. Nivel 1 Conicet.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241095,"idioma_id":5,"titulo":"Impacto del bilingüismo temprano y nivel socioeconómico sobre las funciones ejecutivas","resumen":"Se realizó un estudio para conocer si se mantienen los efectos potenciadores del bilingüismo temprano en poblaciones con Necesidades Básicas Insatisfechas (NBI). Se administró una batería neuropsicológica a 122 adolescentes provenientes del norte de Argentina y sur de Paraguay que incluyó la tarea Test de Stroop, Tarea de Laberintos y Pruebas de Fluidez Verbal para evaluar la flexibilidad cognitiva y control ejecutivo. Se comparó el rendimiento de los participantes organizados en cuatro grupos según nivel socioeconómico (con necesidades básicas satisfechas e insatisfechas) y exposición temprana a una o dos lenguas (español, guaraní-español o español-guaraní). Los resultados refutaron las hipótesis iniciales debido a que los participantes monolingües rindieron mejor que los bilingües y esta diferencia se acrecentó en los grupos con NBI. Se hace necesario un nuevo estudio que amplíe estos hallazgos y compare bilingües y monolingües de una misma comunidad debido a que las diferencias encontradas podrían ser a causa de las características de las diferentes comunidades en las que se trabajó.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241096,"idioma_id":4,"titulo":"Calcium-inulin wheat bread: prebiotic effect and bone mineralisation in growing rats","resumen":"SummaryThe nutritional performance of wheat bread prepared with calcium carbonate and inulin was studied in growing rats fed with three diets (BD: diet containing bread with calcium and inulin, SD: diet with synergy1® and CD: diet control&#8208;AIN 93G&#8208;) up to 60 days. Animals fed with BD consumed less diet and presented a caecal pH (5.5) lower than that of the CD group (7.0) with the highest amount of anaerobic micro&#8208;organisms (1.68 × 1010 cfu g&#8722;1) at 23 days. Microbiota profiles (DGGE) indicated that BD groups presented 66% of similarity and greater variability than the CD group, suggesting changes due to the prebiotic effect of inulin. In the BD group, calcium apparent absorption (AACa: 83%), bone mineral content (18 g kg&#8722;1), proximal tibia density (242 mg cm&#8722;2) and bone volume (BV: 41%) were higher than in the CD group. The decrease in pH due to fermentation in the large intestine increased calcium bioavailability. Although all variables studied on animals fed with diets containing the prebiotic were improved with respect to a control without inulin, in the case of bread diet, many of them were similar to those of the positive control. Consequently, the prebiotic effect was not altered during the baking process. Results suggest that wheat bread, a highly consumed product throughout the world, is an adequate vehicle for including calcium and inulin in healthy food.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241097,"idioma_id":4,"titulo":"Biological activity of the non-microbial fraction of kefir: Antagonism against intestinal pathogens","resumen":"Kefir is a fermented milk obtained by the activity of kefir grains which are composed by lactic and acetic acid bacteria, and yeasts. Many beneficial health effects have been associated with kefir consumption such as stimulation of the immune system and inhibition of pathogenic microorganism. Biological activity of kefir may be attributed to the presence of a complex microbiota as well as the microbial metabolites that are released during fermentation. The aim of this work was to characterize the non-microbial fraction of kefir and to study its antagonism against Escherichia coli, Salmonella spp. and Bacillus cereus. During milk fermentation there was a production of organic acids, mainly lactic and acetic acid, with a consequent decrease in pH and lactose content. The non-microbial fraction of kefir added to nutrient broth at concentrations above 75% v\/v induced a complete inhibition of pathogens growth that could be was ascribed to the presence of undissociated lactic acid. In vitro assays using intestinal epithelial cell model indicates that pre-incubation of cells with non-microbial fraction of kefir did not modify the association\/invasion of Salmonella whereas pre-incubation of Salmonella with this fraction in a condition that do not affect their viability significantly decreased the pathogen´s ability to invade epithelial cells. Lactate exerted a protective effect against Salmonella in a mice model demonstrating the relevance of metabolites present in the non-microbial fraction of kefir produced during milk fermentation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241099,"idioma_id":4,"titulo":"Spinel manganites synthesized by combustion method.  Structural characterization and catalytic activity in the oxidative degradation of organic pollutants","resumen":"Two spinel-type oxides, CuMn2O4 and CoMn2O4 were synthesized by a simple combustion method. The oxides were characterized by X-ray Diffraction, infrared spectroscopy, scanning electron microscopy and atomic absorption spectroscopy. The structures of the obtained oxides were refined by the Rietveld method. The obtained samples were tested in the catalytic degradation of phenol and methyl orange. Two different oxidants were employed: potassium persulfate and  peroxymonosulfate. The catalytic activity was tested, as well as the degradation efficiencies. The best results were obtained with the copper substituted oxides, using oxone as oxidant. With this system, mineralization of total organic carbon (TOC) reached more than 94% within 120 min ofreaction. For cobalt mixed oxides, the TOC mineralization reached as much as 68% in the same condition. The activation mechanisms for the different systems studied in this work are discussedand two different pathways are proposed depending on the oxidant and\/or the substitution metal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241103,"idioma_id":5,"titulo":"Caracterización microbiológica de polen comercial. Reporte Preliminar","resumen":"Pollen production has been increasing in response to consumer demand,presenting itself as a diversification alternative for beekeeping. Although pollenconsumption is promoted due to nutritional and therapeutic properties, there isno standardized method in Argentina for quality pollen production. The aim ofthis work was to study the microbiological quality of commercial pollenconsidering the conservation and form of presentation. Moisture was determinedby oven drying, expressing the results in percentage. The microbiologicalmethods used were mold and yeast counts, total aerobes and total coliforms,Salmonella spp determination and sulfite reducing anaerobes. Moisture resultsranged from 12.9 to 22%. Samples marketed in bulk bag had a significantlyhigher moisture value when stored at room temperature than cooled (F = 6.54,P = 0.02), while fractionated pollen moisture was not significantly differentbetween the two conservation states. The results evidenced the highmicrobiological diversity found, mold and yeast levels were less than 102 UFC\/gfor the 28% of the samples, while for total aerobes the values ranged between103 and 8.5 X 103 UFC\/g. The 0.2% of the samples presented Escherichia coli,being detected in 22% of the samples presence of sulfite reducing anaerobes.The high humidity values make it clear that the methods, drying procedures andtemperature should be standardized. More studies are needed to evaluate thequality throughout the process from harvest to commercialization in order toestablish critical control points to avoid product deterioration.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241105,"idioma_id":4,"titulo":"REJUVENATING EFFECT OF LONG-TERM IGF-I GENE THERAPY IN THE HYPOTHALAMUS OF AGED RATS WITH DOPAMINERGIC DYSFUNCTION","resumen":"The aging female rat constitutes an interesting model of spontaneous and progressive age-related dopaminergic dysfunction as it allows assessing new therapeutic strategies for Parkinson´s disease. Insulin-like growth factor I (IGF-I) is emerging as a powerful neuroprotective molecule which is strongly induced in the central nervous system after different insults. We constructed a helper-dependent recombinant adenoviral vector (HDRAd-IGFI) harboring the gene for rat IGF-I. This was used it to implement long-term IGF-I gene therapy in the hypothalamus of aged female rats, which display hypothalamic dopaminergic (DA) dysfunction and as a consequence, chronic hyperprolactinemia. Rejuvenating long-term IGF-I gene therapy was implemented in young (3 mo.) and aged (24 mo.) female rats, which received a single intrahypothalamic injection of 4 X109 viral particles of either HD-RAd-IGFI or HD-RAd-DsRed (control vector) and were sacrificed 119 days post-injection. In the young animals, neither vector modified serum prolactin (PRL) levels but in the RAd-IGFI-injected aged rats a nearly full reversion of their hyperprolactinemic status was recorded. Morphometric analysis revealed a significant increase in the total number of tyrosine hydroxylase (TH) positive cells in the hypothalamus of experimental as compared with control aged animals (5,874 ± 486 and 3,390 ± 498, respectively). Our results indicate that IGF-I gene therapy in aged female rats is highly effective in rejuvenating the hypothalamic DA neuron groups.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241106,"idioma_id":5,"titulo":"La tormentosa relaci&oacute;n entre las grasas y el desarrollo de la diabetes mellitus tipo 2: actualizado. Parte 2","resumen":"In this part of the review, the functional relationship between lipid and carbohydrate metabolisms and their interdependence is described, from the glucose-fatty acid cycle and the portal hypothesis of insulin resistance to the new knowledge on brown and beige adipocytes, with emphasis on the normal functioning of an endocrine pattern in which its dysfunction is a key factor in the pathophysiology of T2DM and obesity. Ectopic fat deposition in lean tissues due to the inability of the adipose tissue to continuously collect lipids and the endocrine activity of adipocytes is discussed. The production of molecules (adipokines) influencing some of the mechanisms involved in the development of insulin resistance (leptin, adiponectin, TNF-&#945;, resistin, etc.) and beta cell dysfunction is also revisited. The decrease in the oxidative capacity in the mitochondrial respiratory chain and the rebirth of the concept of&nbsp;de novo&nbsp;lipogenesis are described, both effects favouring intracellular lipid accumulation. In lean tissues there are small intracellular lipid reserves that help to maintain the regulation of essential functions; however, when a lipid overload occurs the phenomenon could lead to severe cell dysfunction (lipotoxicity), and death (lipo-apoptosis). The stormy relationship between lipids and the Langerhans? islets goes beyond the functional effort imposed by peripheral insulin-resistance on the &#946; cells, either by the direct effect of lipids or by their derivatives on overall pancreatic islet function. Within a scenario of no insulin deficit, diabetes does not develop.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241120,"idioma_id":5,"titulo":"Estudio comparativo de los parámetros reológicos, ópticos y fisicoquímicos de extractos acuosos de hojas de Bauhinia forficata","resumen":"Objetivos: La diabetes mellitus es señalada como una de las principales amenazas para la salud humana en el siglo XXI. Entre las plantas medicinales utilizadas tradicionalmente para su tratamiento, se encuentra la Bauhinia forficata que crece en Argentina y Brasil. En este trabajo se realizó un estudio comparativo de parámetros reológicos y fisicoquímicos entre diferentes extractos acuosos obtenidos a partir de hojas de Bauhinia forficata recolectadas en la ciudad de Rosario (Argentina) y hojas comerciales vendidas en dietéticas y farmacias. Métodos: Se prepararon soluciones extractivas a partir de las hojas disecadas y solución fisiológica, utilizando los siguientes procedimientos: Cocimiento, Digestión Controlada, Infusión y Maceración. Se realizó la caracterización reológica, óptica y fisicoquímica de los mismos. Resultados y Conclusiones: Los resultados obtenidos son de utilidad para el análisis de la hemocompatibilidad de estos extractos, contribuyendo además a los estudios para la comprensión de sus mecanismos de acción como antidiabéticos en fitomedicina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241121,"idioma_id":4,"titulo":"Industrial Plant at Academic Level for Teaching Industrial Informatics in an Electronic Engineering Undergraduate Degree","resumen":"This paper presents the design of an academic level simulation for an industrial plant and the current status of practice activities proposed for an undergraduate course on industrial automation for electronic engineering students. Strongly focused on professional processes and methods, in particular, it deals with the specific activities developed by electronic engineers at the lower levels of the automation pyramid.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241124,"idioma_id":5,"titulo":"TEORÍA DEL FUNCIONAL DE LA DENSIDAD APLICADA AL ESTUDIO DE LA ADSORCIÓN Y OXIDACIÓN DE MONÓXIDO DE CARBONO EN LA NANOALEACION PLATINO\/IRIDIO","resumen":"xxxxx","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241125,"idioma_id":5,"titulo":"Contenido de minerales en papas crudas, procesadas industrialmente y","resumen":"La papa (Solanum tuberosum L.) es un alimento básico para la humanidad debido a que presenta amplia versatilidad para su preparación en alimentos y  bajo costo de adquisición. Su consumo en Argentina es cercano a 60 kg\/cápita\/año y la principal variedad agronómica destinada al mercado minorista es la Spunta, no así para la elaboración industrial de bastones de papas pre fritos congelados y papas deshidratadas para preparar purés que utilizan variedades con mayor contenido de materia seca.Con el objetivo de obtener datos actualizados de composición mineral de papas producidas y consumidas en Argentina, se determinó el contenido de Na, K, Ca, P, Mg, Zn, Fe y humedad en papas con y sin procesamiento industrial antes y luego de ser sometidas a los procedimientos de cocción más habituales en nuestro país.El hervor de las papas produjo incorporación de agua y pérdida de minerales por solubilización en el agua de cocción, salvo para el sodio que aumentó debido a que la concentración en el agua de cocción resultó muy superior al propio de las papas. Tanto la cocción por microondas como al vapor provocaron una leve disminución del contenido de agua mientras que los minerales no presentaron diferencias significativas respecto de las papas crudas (base seca). Durante la cocción en aceite de los bastones de papas y de las papas pre-fritas congeladas se produjo una significativa pérdida de agua y se incorporó aceite, aun así, el contenido de minerales no presentó variaciones significativas respecto de los productos no cocidos (base seca). Desde el punto de vista nutricional, se destacan los aportes de K y Mg y que todos los productos analizados resultan muy bajos en sodio, con contenidos inferiores a 40 mg\/porción. Cabe considerar que, la preferencia de consumo incluye el agregado de sal durante o luego de la cocción.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241132,"idioma_id":5,"titulo":"Reseña de El tiempo de lo visual","resumen":"Si bien Miguel Ángel Hernández Navarro apunta al comienzo del prólogo que El tiempo de lo visual  tiene la virtud de hacerse cargo de todo lo que sucede hoy en el campo disciplinario de  la Historia del arte (de las artes visuales, se debiera aclarar), dos son estrictamente los temas que se tratan, no sin establecer una relación entre ellos, en el libro: la temporalidad en\/de las imágenes, y la relación entre la Historia del arte y el campo de los denominados Estudios visuales o Cultura visual.El tema del tiempo (apenas comienza, se dice que el libro se ocupa de ?la imagen en el tiempo, así como el tiempo de la imagen?), que se ha venido discutiendo respecto de las historias en general, y con ellas de su capacidad para construir periodizaciones, está vinculado con la heterocronicidad por un lado y con el anacronismo por otro. La heterocronicidad es argumentada fundamentalmente por la diferencia entre la temporalidad de la Modernidad occidental y las historias de las imágenes de otras zonas y culturas, lo que lleva a realizar la estimulante pregunta de si necesitamos todavía del Renacimiento, retomando tanto a los autores que lo constituyeron en mojón de la construcción de una historia lineal y teleológica (Jacob Burckhardt, Erwin Panofsky), como aquellos que comenzaron a cuestionar esa filosofía de la historia. De ese modo, el texto sortea la crítica más obvia de que, si la heterocronicidad aparece recién como una necesidad a partir de que la historia eurocéntrica comienza a prestar atención a otras zonas del munodo y sus culturas, se trataría más de un problema espacial que temporal. Sin embargo, para Moxey no es sólo el Renacimiento el que se constituye a partir de una filosofía de la historia teleológica y con una temporalidad homogénea y lineal, sino también las vanguardias artísticas, a partir de la ya clásica lectura de Clement Greenberg, que  privilegia ?el ataque modernista al naturalismo y al realismo del período anterior como parte de un movimiento teleológico hacia una abstracción cada vez mayor? (2016:77). El problema es que, teniendo en cuenta solamente la definición modernista de las vanguardias presente por excelencia en Greenberg, se sostiene que recién la contemporaneidad  permitió reconocer la heterocronidad o la multiplicidad temporal, cuando si se hubiera tenido en cuenta la diversidad y la heterogeneidad de las denominadas vanguardias históricas hubiera sido posible reconocer esas temporalidades diferenciales y la construcción de relatos múltiples, sin salirse de los límites de la propia Europa.El recorrido por autores que contribuyeron a debilitar una filosofía de la historia lineal y teleológica pero también colonialista incluye a Michel Foucault, Michel de Certeau o Hayden White,  y a los historiadores indios Dipesh Chakrebarty y Ranajit Guha, quienes han señalado que ?muchas de las culturas se las han arreglado muy bien y existen desde hace miles de años sin un concepto teleológico de la historia? (2016:60). Respecto del anacronismo, el historiador del arte que Moxey ubica en un lugar central  es Georges Didi Huberman, con su insistencia de que la presencia fenomenológica de  las imágenes las hace capaces de desafiar el tiempo.  El rescate de la presencia en lugar de la representación es también el de la contemporaneidad de la experiencia estética en lugar de la localización de esa experiencia en un continuo histórico. Esa valiosa proposición puede encontrar resonancias en los conceptos semióticos de intertextualidad (Julia Kristeva), pero especialmente en la concepción de la circulación discursiva de Eliseo Verón, quien desde la sociosemiótica argentina examinó la complejidad de trayectorias que un discurso recorre a lo largo del tiempo, y las diversas redes de sentido que ello conforma. El tiempo de lo visual reconoce las contribuciones de la semiología y semiótica (aunque sin nombrar a los autores aquí citados), pero les discute su focalización en las cuestiones de significación antes que en la sola presencia. Es en esa dirección que en el texto se aboga también por el giro icónico como superador del denominado giro lingüístico, aunque la crítica a la semiótica parece más bien apoyarse en una lectura confusa o bien estrecha: la que equipara referencialidad o, mejor, contenido, con sentido. La sensibilidad respecto del ?aura? de las imágenes, el respeto por la inmediatez de su ubicación en el espacio y en el tiempo, la recuperación de la experiencia permite según Moxey tener en cuenta no tanto lo que los receptores hacen con las imágenes sino lo que las imágenes hacen con ellos. Así, retoma tanto los estudios de la ?cultura material? de Daniel Miller como el concepto de agencia de Alfred Gell, ambos desde la antropología, en el marco de una superación de la distinción sujeto-objeto impulsada en los Estudios de la ciencia entre otros por Bruno Latour. El giro icónico o giro pictorial es inscripto en el desarrollo de los denominados Estudios visuales y la Cultura visual, y leído como superador de la Historia social del arte reinante en la historiografía de las Artes visuales hasta el momento. Autores como el citado Didi Huberman con su recuperación de la la figura de Aby Warburg que reconocía el poder de la imagen para suspender la temporalidad, o el desarrollo de William John Thomas Mitchell con su definición del ?giro pictorial? y su pregunta acerca de ¿qué quieren las imágenes? (2005), son consideradas centrales para el presente de la historia del arte, aunque además en el libro se realiza un detallado recorrido por las diferencias entre los Estudios visuales y la Cultura visual. El indudable interés que presenta el denominado giro icónico que añade la dimensión de la presencia de la imagen, con diferentes acentuaciones y abordajes metodológicos, como los que Moxey retoma ? Elkins y el interés por el análisis material de las obras, Bredekamp con el de la forma, Belting con la perspectiva antropológica que se ocupa de las formas de vida con las que las imágenes han sido animadas, Mitchell con los modos en que la percepción es afectada por los cambios en la visualidad, o Didi Huberman y una fenomenología que reconoce la agencia de la obra de arte (2016:125)-, tiene el valor de poner en paridad a las imágenes, tomando como objeto tanto aquellas que la Modernidad occidental ha considerado obras de arte como las que no (entre las que se encuentran los productos de las culturas no occidentales y de las denominadas culturas populares pero también aquéllas que forman parte de la cultura de masas del siglo XX y XXI). Esa virtud no inhibe la necesidad de realizar una serie de preguntas que, además de rescatar la presencia de las preguntas en El tiempo de lo visual, se entiende que permiten enriquecer todavía más su aporte y continuar reflexionando en torno a lo que proponen los Estudios visuales:-La definición de giro icónico y la construcción de un campo como el de los Estudios visuales, ¿no muestra un excesivo recorte y autonomización de la imagen respecto de otros componentes de los discursos y de la complejidad de los lenguajes contemporáneos, como la del lugar de lo audiovisual, que desde hace décadas se ha demostrado que no comporta la suma de lo visual y lo auditivo sino otros modos de construcción del sentido, pero también de presencia?-En esa línea, la cuestión de la traducción de la imagen con la palabra, que en el libro se juzga a la vez imposible y necesaria, ¿no indica un cierto imperialismo de la imagen y lo visual, en una era en la que lo auditivo y la palabra oral y escrita no solo son tan indudablemente importantes en la cultura como las imágenes, sino que además son esos lenguajes y medios los que en parte vinieron a modificar las fronteras entre lo que es considerado arte y lo que no?- Volviendo a la interesante inversión respecto de  lo que la imagen hace con los receptores, antes de lo que ellos hacen con la imagen, El tiempo de lo visual describe diversas perspectivas para abordar esta inversión, pero todas esas perspectivas, con su insistencia en la imagen como presencia y en el valor afectivo-estético de cada recepción, ¿no recuerdan a la mirada crociana? Ello en sí no tiene nada de negativo, sólo que además de que Benedetto Croce no es citado, estas perspectivas se presentan como nuevas y superadoras. Por último, se toma y se agradece el desafío presentado en el libro respecto de la necesidad de nuevos modos de periodizar las imágenes y\/o las obras de arte, y la seguridad de que ello no sólo comportará una mayor y mejor comprensión del pasado sino un potente efecto en el presente del arte y la cultura.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241134,"idioma_id":4,"titulo":"Soybean Sourdough as Bio-ingredients to Enhances Physical and Functional Properties of Wheat Bakery Products","resumen":"The aim of this study was to evaluate the strain Lactobacillus plantarum C8 as starter culture for soybean sourdough fermentation, in terms of rheological properties, phenolic content and antioxidant activity. After this, wheat breads were prepared with fermented (sourdough) and unfermented soybean flour (control) at three different ratios (4.0:1.0, 3.5:1.0 and 1.5:1.0). Soybean sourdough showed less consistency and increased viscosity compared with unfermented dough. The content of phenolic compounds and the antioxidant activity significantly (p<0.05) increased after lactic fermentation. The overall characteristics of breads depended on the amount of soybean sourdough or flour addition while the best results were obtained with the lower substitution level. In fact, higher specific loaf volume, less crumb hardness and chewiness and intensification in lightness with respect to control breads, were obtained. Besides, sourdough breads showed high phenolic content and antioxidant activity with respect to breads made with unfermented soybean flour. In addition, sourdough breads were widely accepted by the consumers. This study put in evidence that sourdough addition improved the physical and functional properties of traditional wheat bread.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241135,"idioma_id":4,"titulo":"Lactic Fermentation Improved Textural behaviour, Phenolic Compounds and Antioxidant Activity of Chia (Salvia hispanica L.) Dough","resumen":"In this work, autochthonous lactic acid bacteria (LAB) were isolated from chia (Salviahispanica L.) dough and selected on the basis of the kinetics of acidifi cation and proteolyticactivity. Strain no. C8, identifi ed as Lactobacillus plantarum C8, was selected and used as start erto obtain chia sourdough. Lactic acid fermentation increased the organic acid mass fractions(lactic, acetic and phenyl lactic acids to 12.3 g, 1.0 g and 23.8 &#956;g per kg of dough respectively),and antioxidant activities, which increased by approx. 33?40 % compared to unfermentedchia fl our dough. In addition, total phenolic content increased 25 % and its compositionwas strongly modifi ed aft er 24 h of fermentation by L. plantarum C8. Chlorogenic acid wasonly found in the fermented dough (2.5 mg\/g), while ferulic acid was detected from the beginningof fermentation, being 32 % higher in chia sourdough (5.6 mg\/g). The use of fermentedchia sourdough improved the overall characteristics of white bread, includingphysical (e.g. reduced hardness and chewiness of the crumb) and antioxidant properties (25% on average), compared to the white bread. These results indicate that the use of chia sourdoughcould be a promising alternative to improve the technological and antioxidant propertiesof wheat bread. In addition, this work has shown, for the fi rst time, that","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241137,"idioma_id":4,"titulo":"Conservation assessments in climate change scenarios: spatial perspectives for present and future in two Pristidactylus (Squamata: Leiosauridae) lizards from Argentina","resumen":"The consequences of global climate change can already be seen in many physical and biological systems and these effects could change the distribution of suitable areas for a wide variety of organisms to the middle of this century. We analyzed the current habitat use and we projected the suitable area of present conditions into the geographical space of future scenarios (2050), to assess and quantify whether future climate change would affect the distribution and size of suitable environments in two Pristidactylus lizard species. Comparing the habitat use and future forecasts of the two studied species, P. achalensis showed a more restricted use of available resource units (RUs) and a moderate reduction of the potential future area. On the contrary, P. nigroiugulus uses more available RUs and has a considerable area decrease for both future scenarios. These results suggest that both species have a moderately different trend towards reducing available area of suitable habitats, the persistent localities for both 2050 CO2 concentration models, and in the available RUs used. We discussed the relation between size and use of the current habitat, changes in future projections along with the protected areas from present-future and the usefulness of these results in conservation plans. This work illustrates how ectothermic organisms might have to face major changes in their availability suitable areas as a consequence of the effect of future climate change.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241141,"idioma_id":4,"titulo":"Polar factorization of conformal and projective maps of the sphere in the sense of optimal mass transport","resumen":"Let M be a compact Riemannian manifold and let &#956;,d be the associated measure and distance on M. Robert McCann, generalizing results for the Euclidean case by Yann Brenier, obtained the polar factorization of Borel maps S : M -> M pushing forward &#956; to a measure &#957;: each S factors uniquely a.e. into the composition S = T circ U, where U : M -> M is volume preserving and T : M -> M is the optimal map transporting &#956; to &#957; with respect to the cost function d^2\/2. In this article we study the polar factorization of conformal and projective maps of the sphere S^n. For conformal maps, which may be identified with elements of the identity component of O(1,n+1), we prove that the polar factorization in the sense of optimal mass transport coincides with the algebraic polar factorization (Cartan decomposition) of this Lie group. For the projective case, where the group GL_+(n+1) is involved, we find necessary and sufficient conditions for these two factorizations to agree.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241143,"idioma_id":5,"titulo":"Anemia inflamatoria: fisiopatología, diagnóstico y tratamiento","resumen":"La anemia de la Inflamación (AI) es considerada la segunda causa másfrecuente de anemia a nivel mundial después de la deficiencia de hierro.Se observa comúnmente en infecciones crónicas, tumores, traumas, ydesórdenes inflamatorios. La AI es típicamente normocítica normocrómicausualmente moderada y se produce por una hipoferremia como resultadodel secuestro de hierro en el sistema retículo endotelial, de la reducciónde la eritropoyesis y de la inhibición de la absorción del hierro en intestino.La patogenia de la AI está mediada por citoquinas inflamatorias yhepcidina, péptido producido en el hígado, que regulan la homeostasis delhierro, actúan suprimiendo la eritropoyesis, y la vida media de los eritrocitosse encuentra ligeramente acortada. Los métodos diagnósticos de rutinaque se describen en esta revisión pueden ser de utilidad, pero quedaráun grupo de estados anémicos con alta sospecha de AI que no podrán serfácilmente clasificados. Recientemente se han desarrollado inmunoensayospara determinar hepcidina y citoquinas inflamatorias que podrán colaborar,en un futuro, para un diagnóstico correcto. Existen actualmente modelosexperimentales de AI en ratones, los cuales podrían ser útiles para evaluardiferentes tratamientos. En este sentido, los inhibidores de la hepcidina ydiversos moduladores inflamatorios aparecen como terapias prometedoras.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241144,"idioma_id":5,"titulo":"Identificación de fracciones censales de mayor aptitud para la localización de instituciones educativas en el partido de Moreno (Buenos Aires, Argentina). Ejemplo de evaluación multicriterio en formato vectorial","resumen":"Se presenta la metodología y los resultados de un ejercicio de evaluación multicriterio ensayado para la determinación de fracciones censales de mayor aptitud para la localización de nuevas instituciones educativas de nivel primario y secundario en el partido de Moreno, provincia de Buenos Aires, Argentina. La metodología incluyó elaboración de cartografía específica sobre el tema en cuestión (localización de instituciones educativas y características sociodemográficas por fracción censal) en formato vectorial y la selección de un método de evaluación multicriterio que permita la combinación de variables necesarias para identificar las áreas con mayores necesidades educativas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241145,"idioma_id":5,"titulo":"Agricultura, Ambiente y Sociedad en Yocavil: análisis espacial de evaluación multicriterio con clasificaciones fuzzy","resumen":"Se aplican técnicas de evaluación multicriterio con metodología fuzzy que permiten avanzar en la validación de modelos de aptitud espacial para el desarrollo de la agricultura prehispánica y actual en un sector del valle de Yocavil meridional (Catamarca, Argentina). Se emplea asimismo el método de Combinación Lineal Ponderada utilizando Sistemas de Información Geográfica. Se observó que el área con mayor potencial para la agricultura coincide principalmente con el registro arqueológico prehispánico. La evolución histórica de la producción agrícola desde tiempos prehispánicos hasta el presente permite postular que las condiciones ambientales no son las únicas ni las que más influyen en la organización económica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241146,"idioma_id":5,"titulo":"Los Sistemas de Información Geográfica en la Arqueología Argentina","resumen":"Se analiza la intensidad del uso de Sistemas de Información Geográfica (SIG) en la Arqueología Argentina a partir del análisis de las Actas y Libros de Resúmenes de los últimos seis Congresos Nacionales de Arqueología Argentina, que cubren un período de dieciséis años. La información se complementa con publicaciones en revistas generales de Geografía y Arqueología. Se observa un avance creciente de las investigaciones arqueológicas que abordan temas de uso del espacio\/espacialidad\/paisaje prehispánico\/histórico y temas afines, aunque son pocos los que utilizan como herramienta científica a los SIG. Se plantea la necesidad de una mayor articulación entre marcos teórico-metodológicos de la Geografía y la Arqueología, por cuanto ambas disciplinas se abocan al estudio de la relación entre la sociedad y el medio y sus aplicaciones a la gestión del ordenamiento territorial.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241147,"idioma_id":4,"titulo":"LaNi 5 hydride powder flowability as a function of activation and hydrogen content","resumen":"Volume expansion of hydrogen absorbing materials, together with inter-particle friction can cause tension accumulation in hydride containers during absorption. When hydride particles absorb hydrogen there is an important volume increase, in the order of 25%. Particles have to accommodate to the container geometry but this movement is opposed by inter-particle friction. Under certain conditions tensions can build up, compromising the mechanical integrity of the container. This phenomenon needs to be addressed at the design stage to avoid mechanical failure of the container.Flow behavior of powder materials is a relevant technological field, usually addressed by means of qualitative or quantitative flowability measuring devices. The rotating drum technique, while mainly qualitative, is well established and can be modified into a completely sealed unit. To determine the flowability of a hydride under different activation stages and hydrogen content levels we developed a rotating drum device that can be pressurized with hydrogen or depressurized. We report particle size evolution and flowability measurements of a hydrogen absorbing material (LaNi5) at different stages of activation for both absorbed and desorbed states. The results of the present study show that the flowability of LaNi5 in more dependent on the degree of activation of the sample than on hydrogen absorption state.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241148,"idioma_id":4,"titulo":"An experimental study of the aerodynamic dispersion of loose aggregates in an accelerating flow","resumen":"The dispersion of powders in gas flows is relevant in some powder processing techniques, in dry powder inhalers and in particle size analysers, among others. When using small particle sizes, the powder tends to form stronger aggregates and the dispersion becomes more difficult. There are many approaches to the dispersion process but most include collisions as one of the possible agglomerate break-up mechanisms. This is not always a satisfactory solution as particles may get contaminated or reduced. In the present work we explore the dispersion of powder aggregates in an accelerating flow with no particle-wall collisions. We built a fluid-dynamic device with a simple geometry consisting of a sharp slit, producing a rapidly converging flow at the entrance and a planar jet at the exit. A powder feeder exited with an ultrasonic actuator was used to generate single powder aggregates. The stationary flow field was calculated numerically and the velocity and degree of aggregate dispersion were assessed based on imaging results. In all the cases tested, erosion of the aggregates could be observed. In the case with the highest suction pressure, a different mechanism arises, which leads to the disintegration of the aggregate and a significantly better dispersion of the powder.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241149,"idioma_id":5,"titulo":"18F-DOPA PET\/TC para el diagnóstico del hiperinsulinismo congénito Open access","resumen":"El hiperinsulinismo congénito (HIC) es una enfermedad poco frecuente, de causa genética, que produce hipoglucemia debido a la secreción excesiva y\/o desordenada de insulina. De no ser detectada tempranamente produce un severo daño neurológico con un impacto importante en el desarrollo del niño. Se han descrito mutaciones en nueve genes como causa de HIC, aunque histológicamente se describen tres tipos mayores de esta entidad (difuso [50%], focal [40%] y atípico [10%]), cuyo manejo difiere drásticamente1. Los pacientes con enfermedad focal requieren una pancreatectomía parcial que remueva la zona de la lesión para proveer una cura completa sin las comorbilidades de la pancreatectomía total. Esta intervención queda restringida para la enfermedad difusa sin respuesta al tratamiento médico, cuya morbilidad es la diabetes mellitus iatrogénica y la insuficiencia pancreática exócrina2......","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241150,"idioma_id":4,"titulo":"Electrochemical comparison of LiFePO4 synthesized by a solid-state method using either microwave heating or a tube furnace","resumen":"Abstract: LiFePO4\/C composites were successfully prepared by a solid-state reaction in order to compare conventional heat treatment and microwave-assisted synthesis at different times of sintering. Microwave-assisted synthesis is interesting due to the fact that energy and inert gas consumption can be greatly reduced with respect to the conventional treatment, resulting in a cheaper synthesis method. The relationship between particle morphology and crystal structure using the composite synthesis was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray diffraction (XRD) with refinements of the crystal structures carried out by the Rietveld method. In addition, the electrochemical performances were evaluated using constant current charge\/discharge tests, cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS). It was observed that the samples prepared by microwave heating had a better electrochemical behavior than those prepared in a conventional furnace. Also, in general, a higher sintering time improved the electrochemical behavior, but with increased particle sizes, and consequently, a decreased specific capacity. Graphical Abstract: [Figure not available: see fulltext.].","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241151,"idioma_id":5,"titulo":"Concepciones sobre la enseñanza y el aprendizaje en docentes de carreras de salud","resumen":"Introducción.Las concepciones de los docentes influyen en la interpretación de las situaciones educativas y en su práctica pedagógica cotidiana. Conocerlas es importante para planificar procesos de formación.Objetivos.Describir las concepciones sobre el aprendizaje y la enseñanza que tienen los docentes de las carreras de salud de una facultad, establecer si esas concepciones tienen semejanzas con algunas de las clasificaciones descritas en otros trabajos y si estos docentes sostienen concepciones cercanas a las perspectivas constructivistas.Sujetos y métodos.El estudio se realizó desde la perspectiva de la fenomenografía con entrevistas semiestructuradas. La muestra se seleccionó en forma intencional y fue de 28 docentes de carreras de salud con formación pedagógica. Se llevó a cabo un análisis por dimensión y otro sobre la consistencia interna de cada entrevista.Resultados.A partir de los análisis por dimensión y de cada entrevista, se elaboraron tres perfiles de concepciones: docente proveedor-estudiante reproductor pasivo, docente entrenador-estudiante reproductor activo y docente tutor-estudiante gestor.Conclusiones.Los docentes entrevistados, aun teniendo formación específica en educación, no conciben el aprendizaje como un proceso de construcción, sino como la incorporación del conocimiento socialmente validado. Además, utilizan terminología que proviene del constructivismo sin poder dar cuenta del significado de estos términos en el contexto de la teoría del aprendizaje que los sustenta. En la comparación con otros autores, los perfiles elaborados a partir de las entrevistas estarían más cerca de concepciones directas e interpretativas del aprendizaje y no aparecen perfiles en los que claramente se defina el aprendizaje como proceso de construcción de conocimientos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241152,"idioma_id":4,"titulo":"Common scab performance of tetraploid potato genotypes from Argentina","resumen":"Fifty potato genotypes from the breeding program were evaluated against common scab, caused by Streptomyces sp., in a greenhouse of the Balcarce Integrated Unit (INTA-FCA, UNMdP). The isolation of Streptomyces sp. was done from tubers that exhibited symptoms of the disease. The 'seed' tubers of each genotype were planted in plastic pots containing a mixture of sterilized soil and sand, previously inoculated with the bacteria. Cv. Bintje was included because of its known susceptibility to the disease. Plants naturally completed their cycle and tuber´s scab symptoms were evaluated. Affected tuber surface (%), type of damage and relative scab index (RSI) were calculated for each tuber of each genotype. A randomized complete block design with three replications was used. It was determined that there were significant differences among genotypes in affected tuber surface, type of damage and RSI. Six genotypes with a potentially resistant behavior to common scab were identified. This characterization of infection with common scab will allow resistance genes to be incorporated against this disease in breeding programs.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241157,"idioma_id":4,"titulo":"Use of easy measurable phenotypic traits as a complementary approach to evaluate the population structure and diversity in a high heterozygous panel of tetraploid clones and cultivars","resumen":"Diversity in crops is fundamental for plant breeding efforts. An accurate assessment of genetic diversity, using molecular markers, such as single nucleotide polymorphism (SNPs), must be able to reveal the structure of the population under study. A characterization of population structure using easy measurable phenotypic traits could be a preliminary and low-cost approach to elucidate the genetic structure of a population. A potato population of 183 genotypes was evaluated using 4,859 high-quality SNPs and 19 phenotypic traits commonly recorded in potato breeding programs. A Bayesian approach, Minimum Spanning Tree and diversity estimator, as well as multivariate analysis based on phenotypic traits, were adopted to assess the population structure.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241160,"idioma_id":4,"titulo":"Non-linear plank problems and polynomial inequalities","resumen":"We study lower bounds for the norm of the product of polynomials and their applications to the so called emph{plank problem.} We are particularly interested in polynomials on finite dimensional Banach spaces, in which case our results improve previous works when the number of polynomials is large.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241161,"idioma_id":4,"titulo":"On the linear polarization constants of finite dimensional spaces","resumen":"We study the linear polarization constants of finite dimensional Banach spaces. We obtain the correct asymptotic behaviour of these constants for the spaces ld p : they behave as p&#8730; d if 1 &#8804; p < 2. and as &#8730; d if 2 &#8804; p < &#8734;. For p = &#8734; we get the asymptotic behaviour up to a logarithmic factor.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241162,"idioma_id":4,"titulo":"Thickness determination of anodic titanium oxide films by electron probe microanalysis","resumen":"Thin film thickness can be readily associated to the X-ray intensities emitted under electron bombardment. The aim of this work is to develop a method for measuring titanium oxide thicknesses in biomaterials from the X-ray spectra induced in a scanning electron microscope. The oxide layers studied were generated with different anodizing voltages applied in phosphoric and boric acid solution (H3PO4\/H3BO3). The oxygen K&#945; intensity was registered for each sample and related to the corresponding thickness. In order to account for local material alterations, a recalibration is shown to be necessary; Rutherford backscattering spectroscopy was used at this stage. The method is useful for TiO2 thicknesses in the range of interest for dental and orthopedic implants (10?100&nbsp;nm), and it could be extended to greater thicknesses by adequately selecting the electron beam energy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241166,"idioma_id":5,"titulo":"Educación Intercultural Bilingüe: El otro en la diversidad","resumen":"El término ?diversidad? para designar la alteridad cultural fue utilizado por la teoría evolucionista, constitutiva de las ciencias antropológicas a fines del siglo XIX, como sinónimo de ?diferencia? (Boivin et al., 1998). Pero ello fue cambiando, ya que durante el lapso que va desde las dos guerras mundiales, las escuelas antropológicas comienzan a utilizar el término diversidad de manera sistemática y sustitutiva al de diferencia. Es aquí donde nos posicionaremos durante el desarrollo del presente ensayo: desde la alteridad como sinónimo de diversidad.Para ver y comprender el modo en que se construyó la otredad a partir de la diversidad, tomaremos aportes de la teoría estructuralista de Levi Strauss, específicamente el concepto de etnocentrismo","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241169,"idioma_id":5,"titulo":"Mejoramiento del desempeño térmico de sistemas de construcción no convencional en el NEA: evaluación y propuesta de atenuación de puentes térmicos","resumen":"El buen comportamiento higrotérmico de las envolventes perimetrales de edificios construidos en el Nordeste Argentino (NEA) resulta de primordial importancia dado el clima la región registra. No obstante, éste se ve desmejorado debido a la gran cantidad de heterogeneidades (puentes térmicos) que la naturaleza estructural de los sistemas de construcción no convencional genera. Posibilitando mayor flujo de calor a través de las secciones transversales. Teniendo en cuenta que únicamente el 20% de este tipo de soluciones constructivas resulta apto ante este punto crítico intrínseco, el presente trabajo propone su evaluación y atenuación mediante pautas de diseño.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241170,"idioma_id":5,"titulo":"Desempeño higrotérmico de carpinterías de edificios del NEA según análisis de puentes térmicos","resumen":"Se estudia el desempeño higrotérmico de tipologías de carpinterías, frecuentemente utilizadas, en edificaciones de las ciudades de Resistencia y Corrientes. Para determinar el valor de transmitancia térmica media ponderada, su encuadre en la clasificación propuesta por la Norma IRAM 11507-4, y la ubicación y comportamiento de los puentes térmicos. Datos recabados para estipular el nivel de eficiencia energética de estos componentes. Proponiendo soluciones tecnológicas constructivas de rehabilitación térmica para las carpinterías que se verifican deficientes. Utilizando a modo de validación y comparación de los resultados, simulaciones en software THERM y WINDOW versión 6.3.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241462,"idioma_id":4,"titulo":"Host Amplification in a Dithioacetal-Based Dynamic Covalent","resumen":"Molecular amplification in a dithioacetal-based dynamic library is described for the first time. The homatropine induced selection; amplification and isolation of one cyclophane host demonstrate the utility of dithioacetal exchange for preparing responsive dynamic libraries. Nuclear magnetic resonance and isothermal titration calorimetry analysis suggest that the amplified macrocycle forms a 1:1 complex with the template. This is the first report about a host:guest system involving a dithioacetal cyclophane.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241543,"idioma_id":4,"titulo":"Community-based cardiovascular health promotion in Argentina. A systematic review","resumen":"In Argentina, cardiovascular disease (CVD) accounts for 30% of deaths and more than 600 000 disability-adjusted life years. However, no reviews describing local studies on interventions to address CVD risk factors have been identified. The purpose of this study is to characterize those population-based interventions and public policies implemented in Argentina to reduce the burden of cardiovascular disease with an adequate evaluation of their impact on population health. We conducted a systematic review of studies that assessed interventions in health promotion and\/or primary prevention conducted in adult populations of Argentina, addressing specific CVD factors, from 1999 to 2016. We searched major bibliographic databases, grey literature, ministries and secretariats of health, and academic national libraries. Key informants, non-governmental organizations, universities, hospitals and experts were also contacted. We applied specific inclusion criteria. We assessed the methodological quality of the studies and reported the effectiveness and impact of population interventions and policies, as well as process evaluations´ characteristics. After removing duplicates we identified 1686 references from databases. After reviewing title and abstracts 18 studies were selected, five of them corresponded to evaluations of public policies-all addressing tobacco smoking. We presented a structured review of each experience. Most of the studies were deemed to entail moderate or high risk of bias. We summarized the findings and characteristics of these studies, including implementation strategies, process and impact evaluation. This is the first systematic review of interventions focused on primary prevention and health promotion to counter CVD and diabetes in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241546,"idioma_id":5,"titulo":"ACCESO A LA JUSTICIA  DE LAS ADULTAS MAYORES VÍCTIMAS DE VIOLENCIA DE GÉNERO","resumen":"El presente trabajo tiene como objetivo tratar complejos aspectos de la problemática de la gestión y organización de la atención jurídica a las víctimas de violencia de género, adultas mayores, indagando sobre los diferentes canales de acceso a la justicia para este colectivo y las herramientas sociales disponibles para la mitigación del problema. El método deductivo indirecto y de conclusión mediata fue el más pertinente para abordar el estudio, dado que permitió extraer e inferir conclusiones, de una proposición general. A su vez, aquí existe, como puede colegirse de la descripción de la hipótesis, una premisa mayor, relativa a la mayor situación de vulnerabilidad de las adultas mayores de 60 años, en conexión con la violencia de género, mientras que también se puede apreciar una premisa menor relacionada con el conocimiento o creencia en relación a la justicia y el acceso que tiene a ella este grupo en estado de vulnerabilidad, para finalmente arribar a una conclusión en relación al caudal de casos estudiados. La metodología de trabajo se basa aquí en el estudio del material habido a partir del trabajo de investigación realizado en el marco del Proyecto de Investigación: 'Adultas Mayores Víctimas de Violencia de Género: Acceso a la justicia en defensa de sus derechos? (DeCyT 1438, Facultad de Derecho, Universidad de Buenos Aires).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241547,"idioma_id":4,"titulo":"NOVEL MICROMORPHOLOGICAL FEATURES OF WOOD AND BARK OF ARGENTINEAN SIMAROUBACEAE","resumen":"Simaroubaceae is a family of about 22 genera and 100 species of mainly tropical and subtropical trees and shrubs and it is generally considered to be a heterogeneous group. In Argentina, Simaroubaceae is represented by three genera and four species, one of these is exotic: Ailanthus altissima (Mill.) Swingle while the other three are native: Castela coccinea Griseb., C. tweedii Planch.and Picrasma crenata (Vell.) Engl. Wood and bark anatomies of the Argentinean species were studied in an effort to find distinctive features for the genera and species within this family. Transverse, tangential and radial sections of the specimens were prepared and macerated according to conventional techniques; microscopic examination was performed by light microscopy and scanning electron microscopy. It was possible to make a key for the species and genera using a combination of qualitative (presence\/absence of wood growth rings, porosity, abundance of parenchyma, occurrence of crystals, etc.), and quantitative features (vessels per square millimetre, tangential diameter of vessel lumina, etc.). The wood and bark characteristics obtained provide new evidence of the heterogeneous nature of the family. From an ecological point of view, according to vessel size, vessel number, mesomorphy and vulnerability index, the wood of the studied species belonging to Castela genus were characterised as xeromorphic, while the other genera were characterised as mesomorphic.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241554,"idioma_id":5,"titulo":"Breves reflexiones sobre discapacidad y curriculum universitario en Argentina","resumen":"El mundo profesionalestá acusado de ineficacia y deshonestidad, y los centros de formaciónprofesional de no saber enseñar las nociones elementales de una práctica eficazy ética. La Facultadde Derecho de la Universidad Nacional de Rosario, es un ejemplo de ineficacia,porque da demasiada trascendencia al conocimiento científico teórico, en suplan de estudio. En este artículo, mostraremos a través del tema?discapacidad?, dentro del programa de la materia Derecho de la Ancianidad, el cambiode método didáctico llevado a cabo entre los años 2005 y 2011. Estasmodificaciones, se realizaron por medio de innovaciones, que les generaronmayor incomodidad a los estudiantes, pero que los preparará para el futuroprofesional.&nbsp; Estas innovacionesmejorarán la práctica profesional y la calidad de vida de la población.&nbsp;&nbsp; ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241555,"idioma_id":4,"titulo":"Lactobacillus casei BL23 Produces Microvesicles Carrying Proteins That Have Been Associated with Its Probiotic Effect","resumen":"Archaea, bacteria, and eukarya secrete membrane microvesicles (MVs) as a mechanism for intercellular communication. We report the isolation and characterization of MVs from the probiotic strain Lactobacillus casei BL23. MVs were characterized using analytical high performance techniques, DLS, AFM and TEM. Similar to what has been described for other Gram-positive bacteria, MVs were on the nanometric size range (30?50 nm). MVs carried cytoplasmic components such as DNA, RNA and proteins. Using a proteomic approach (LC-MS), we identi&#64257;ed a total of 103 proteins; 13 exclusively present in the MVs. The MVs content included cell envelope associated and secretory proteins, heat and cold shock proteins, several metabolic enzymes, proteases, structural components of the ribosome, membrane transporters, cell wall-associated hydrolases and phage related proteins. In particular, we identi&#64257;ed proteins described as mediators of Lactobacillus? probiotic effects such as p40, p75 and the product of LCABL_31160, annotated as an adhesion protein. The presence of these proteins suggests a role for the MVs in the bacteria-gastrointestinal cells interface. The expression and furtherencapsulation of proteins into MVs of GRAS (Generally Recognized as Safe) bacteria could represent a scienti&#64257;c novelty, with applications in food, nutraceuticals and clinical therapies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241556,"idioma_id":4,"titulo":"Alternate care of two nests by a Red-tailed Comet (Sappho sparganurus)","resumen":"The first case of overlapping broodsfor the Red-tailed Comet (Sapphosparganurus) is documented. While feeding two chicks from a firstbrood, a female simultaneously began to build a secondnest and successfully raised two young in each. The length of overlap ofthe two nests was estimated in 17 days. This is the firstrecord of partial nest overlap for a hummingbird species in a temperate area inthe Southern Hemisphere. In addition, my observations extend the altitudinal limitof this species 260 m below the previously lower boundary, which was for the non-breeding season.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241557,"idioma_id":5,"titulo":"Primeros registros de nidificación del Vencejo de Tormenta (Chaetura meridionalis) en Argentina","resumen":"En este trabajose dan a conocer los primeros registros de nidificación del Vencejo de Tormenta(Chaetura meridionalis) enArgentina. Entre el 3 y el 6 de diciembre de 2015, fueron hallados dos nidos deesta especie en un bosque chaqueño del centro de Argentina. Los mismos estabanubicados en huecos naturales de quebrachos blancos. Uno de los nidos&nbsp; contenía tres pichones y el otro cinco. Comola especie está presente durante la época reproductiva en el centro y norte deArgentina, se asumía que nidificaba en el país, pero hasta el momento no habíaregistros concretos. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241558,"idioma_id":5,"titulo":"Nuevas tecnologías de la información como facilitadoras de  Aprendizaje significativo","resumen":"En este trabajo se propone abordar la potencialidad de las TIC para promover aprendizaje significativo asumiendo que, en la actualidad, existe consenso en la vigencia de ese marco teórico enriquecido con los diversos aportes teóricos que ha recibido desde la década del ´60 y que, al mismo tiempo, las TIC posibilitan nuevas formas para el acceso a la educación dado que las instancias de aprendizaje se amplían ante una gran variedad de aplicaciones y recursos disponibles en Internet. Realizamos un análisis, desde el marco teórico del aprendizaje significativo, de tres aplicaciones informáticas para la enseñanza en las áreas de ciencias exactas y naturales: CMapTools, GeoGebra y Modellus en el contexto de una posible secuencia de enseñanza en el nivel secundario para el tópico de física ?tiro parabólico?.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241559,"idioma_id":4,"titulo":"Lethality and histopathological alterations caused by Phoneutria nigriventer spider venom from Argentina: Neutralization of lethality by experimental and therapeutic antivenoms","resumen":"Although the spiders of the genus Phoneutria cause envenomation and their presence has been described in several provinces of the north of Argentina, they are not as common as other spiders of sanitary importance. In the present work, we studied the toxicity of samples of venom of Phoneutria spiders from the provinces of Misiones (where severe envenomation and deaths by Phoneutria have been recorded) and Jujuy (where no deaths have been recorded and severe envenomations are not frequent). To this end, we assessed the lethal potency in mice and guinea pigs and the histopathological alterations caused by both venoms, as well as the neutralization by the commonly used therapeutic antivenom produced by the Butantan Institute in Brazil and by an experimental antivenom developed with venom of P. nigriventer from Misiones. There were no differences in the lethality of the venoms of spiders from both regions. Post mortem examination showed that the heart and lungs were the most affected organs, while important pulmonary edema was seen macroscopically. Histological analysis showed edema, atelectasis, emphysema and cardiac lesion in both experimental models. The antivenoms assayed showed good neutralization of the venoms in the two experimental models. Despite the different geographic origins, the venoms showed similar toxicity and both the experimental antivenom and therapeutic antivenmos were able to neutralize the venoms of Argentinean P. nigriventer.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241560,"idioma_id":4,"titulo":"Toxicity of the venom of Latrodectus (Araneae: Theridiidae) spiders from different regions of Argentina and neutralization by therapeutic antivenoms","resumen":"&ldquo;Black widow&rdquo; spiders belong to the genus Latrodectus and are one of the few spiders in the world whose bite can cause severe envenomation in humans and domestic animals. In Argentina, these spiders are distributed throughout the country and are responsible for the highest number of bites by spiders of toxicological sanitary interest. Here, we studied the toxicity and some biochemical and immunochemical characteristics of eighteen venom samples from Latrodectus spiders from eight different provinces of Argentina, and the neutralization of some of these samples by two therapeutic antivenoms used in the country for the treatment of envenomation and by a anti-Latrodectus antivenom prepared against the venom of Latrodectus mactans from Mexico. We observed important toxicity in all the samples studied and a variation in the toxicity of samples, even in those from the same region and province and even in the same Latrodectus species from the same region. The therapeutic antivenoms efficiently neutralized all the venoms studied.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241562,"idioma_id":5,"titulo":"Accidentes y muertes por animales venenosos en Argentina durante el período 2000-2011.","resumen":"En Argentina los accidentes causados por animales venenosos constituyen un problema de salud pública. En este estudio analizamos los accidentes y muertes por envenenamientos por mordedura o picadura de serpientes, escorpiones y arañas, y las muertes causadas por abejas-avispas-avispones, centípedos, animales marinos, otros artrópodos y otros animales venenosos en Argentina, recibidos por las autoridades sanitarias nacionales. Se analizó la información sobre accidentes y muertes producidas por este tipo de animales que fueron recibidas por el Ministerio de Salud de la Nación durante el período 2000-2011. Debido al tipo de sistema de notificación solo se pudieron calcular tasas de morbilidad y letalidad en los accidentes por arañas, escorpiones y serpientes. Contrariamente a lo que se suponía, no fueron estos los grupos que mayor cantidad de muertes causaron en el período de estudio, sino los himenópteros (abejas-avispas- avispones).El actual esquema de notificación de envenenamiento por animales venenosos provee información importante para el sistema sanitario. Sin embargo, deben realizarse modificaciones a fin de mejorar el conocimiento&nbsp; epidemiológico referente a envenenamientos por la mordedura o picadura de animales venenosos. De esta manera, se podrá progresar en la implementación de las medidas de prevención de estas patologías, su atención a nivel del primer nivel asistencial y la planificación de la producción de antivenenos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241563,"idioma_id":5,"titulo":"Empresas Británicas en el Rio de la Plata: The Montevideo Waterworks Company, 1879-1947","resumen":"Durante la primera economía global, el Río de la Plata fue uno de los destinos prioritarios de la inversión británica.  Entre los grupos económicos que gestionaron dicha inversión se destacaba  River Plate Trust, cuya matriz The River Plate, Trust, Loan & Agency, fue creada en 1881 para desarrollar inversiones y ejercer la representación de empresas británicas en Argentina y en Uruguay. The Montevideo Waterworks Company fue la primera empresa de servicios públicos gestionada por el grupo River Plate Trust. Esta empresa tuvo un ciclo de vida muy extendido y rentable desde su creación en 1879 hasta su venta y transferencia al estado uruguayo en 1948.  El artículo examina la evolución de su capital, las utilidades y los dividendos, a fin de comparar su desempeño económico con la empresa británica de aguas corrientes que operaba en Rosario bajo el control del mismo grupo. El objetivo general del trabajo es evaluar si las decisiones de inversión de las empresas británicas variaban según las condiciones políticas y económicas de la economía receptora de la inversión.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241566,"idioma_id":5,"titulo":"Protocolos para lactoinducción: análisis productivo en vacas y vaquillonas lecheras normales y con problemas reproductivos","resumen":"El objetivo del presente trabajo fue evaluar la producción y calidad de leche, como también un breve análisis de costo por aplicar un tratamiento de inducción hormonal de la lactancia, en 9 vaquillonas con mérito genético que no lograron preñarse durante fines del año 2011 y principios del 2012, comparado con 9 vacas de primera lactancia natural. El ensayo se llevó a cabo en un tambo de la Cuenca Mar y Sierras. El tratamiento se realizó durante el mes de abril de 2012 y se evaluó la producción de leche promedio teniendo en cuenta los datos brindados por 6 controles lecheros sucesivos. La inducción hormonal de la lactancia pretende simular, los estadios finales de la preñez y el momento del parto, para que en aproximadamente 21 días los animales comiencen con una lactancia semejante a la que se produce luego de una parición normal. Se observó una mayor producción de leche en las vaquillonas con lactancia natural (5383 ± 317 Kg) versus aquellas con lactancia inducida (4338 ± 225 Kg). Sin embargo, el tratamiento hormonal resultó eficaz para producir una lactancia artificial con buena producción de leche. En este trabajo la respuesta a la inducción fue de un 100%, donde no sólo las vaquillonas lograron una lactancia similar a una normal, sino que además se preñaron, y continuaron su ciclo productivo dentro del tambo no debiendo ser descartadas. Si bien la producción de estas vaquillonas fue menor a la esperada luego de un parto normal, fueron lo suficientemente interesantes, en cuanto a litros y días en leche, como para justificar la realización del tratamiento. En 13,7 días, estas vaquillonas que iban a ser descartadas, lograron cubrir con su propia producción de leche, los costos ocasionados por el tratamiento hormonal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241567,"idioma_id":5,"titulo":"Efectos constrastantes de la progesterona sobre la fertilidad de las vacas de leche y de carne. Parte I. Exposición de progesterona previo a la IA y fertilidad","resumen":"El rol de la progesterona en el mantenimiento de la preñez es bien conocido en los bovinos. Existen diferencias importantes entre vacas lecheras y de carne debido a diferencias en las concentraciones de progesterona durante el reinicio de los ciclos estrales posparto, la tasa de crecimiento y maduración folicular, las proporciones de onda 2 y 3-folicular en el ciclo, y otros efectos sobre los resultados de preñez por inseminación artificial (P \/ IA).  Debido a que las proporciones de vacas anovulatorias antes del inicio del período de inseminación artificial (IA) son mayores y más variables en la vaca de carne (generalmente entre 30 y 70%) que en las vacas lecheras (25%), por este motivo los programas de IA se desarrollaron para acomodar a las vacas de carne ya sean tanto anovulatorias como cíclicas. La incorporación de un progestágeno como parte de un programa de IA en vacas de carne aumentó la P \/ IA porque redujo la proporción de vacas que tenían una prematura regresión lútea y fases lúteas cortas posterior a una IA.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241569,"idioma_id":5,"titulo":"ANÁLISIS PRODUCTIVO Y REPRODUCTIVO DE PROTOCOLOS PARA LACTOINDUCCIÓN EN VACAS Y VAQUILLONAS","resumen":"El objetivo del presente trabajo fue evaluar la respuesta productiva y reproductiva a dos tratamientos de lactoinducción. Se seleccionaron 327 vacas de raza Holstein que presentaron trastornos reproductivos que impedían llevar a término una gestación. Se dividieron en forma aleatoria en dos grupos, 160 fueron tratadas con un protocolo basado en la aplicación de benzoato de estradiol (Tratamiento A) y 167 con otro basado en el empleo de cipionato de estradiol (Tratamiento B). Ambos métodos intentaron simular los procesos endócrinos que caracterizan las etapas finales de la gestación y el parto. En relación a la producción de leche se observó que el logro de una lactancia a 305 días no dependió del tratamiento utilizado. El volumen de leche producida en la misma tampoco estuvo asociado ni al tratamiento aplicado, ni a la presencia\/ausencia de mastitis, ni al período de seca aplicado pero sí al número de lactancia (1 lactancia: 6530,96 litros; 2-4 lactancias: 7531,76 litros; p<0,05). El intervalo inicio de tratamiento-pico de producción dependió del tratamiento utilizado (A: 91; B: 66; p<0.05). En composición de la leche sólo hubo diferencias significativas en los porcentajes de proteínas y grasa entre ambos tratamientos (proteínaA: 3,71; proteínaB: 3,62; grasaA: 3,87; grasaB: 3,71 respectivamente). La presencia de mastitis sólo afectó al porcentaje de sólidos totales (sanas: 13,31; enfermas: 12,77; p<0,05). La presencia de quistes no estuvo asociada al tratamiento pero sí la ocurrencia de abortos (A: 10; B: 23; p<0.05). No hubo asociación entre el tipo de rechazo sufrido y el estado sanitario de la ubre. Si hubo asociación entre el logro de una preñez y el motivo del tratamiento, las vacas abortadas tuvieron 2,56 veces más probabilidad de preñarse que las infértiles y las tratadas con el protocolo A tuvieron 1,73 veces más probabilidad de parir que las tratadas con el protocolo B.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241570,"idioma_id":5,"titulo":"Entre matrices y consensos: el ilusorio uso de los paradigmas en las Cs. Sociales","resumen":"Un paradigma define los problemas y métodos legítimos de un campo de investigación para generaciones sucesivas de científicos; constituye una suerte de matriz con conceptos y significaciones en las que se puede introducir, sin embargo, un aporte subjetivo, hasta que las contradicciones internas y las anomalías que se van verificando en la actividad científica dan lugar, merced a un logro que facilite la resolución de esas anomalías, a un nuevo paradigma.Algunos de los ejemplos históricos que da Kuhn en su obra, muestran justamente que estas realizaciones científicas tienen de común el hecho de que hayan sido  logros que no tenían precedentes y 2) desarrollos, lo bastante insuficientes e incompletos, como para ser resueltos por la comunidad científica .En el caso de las ciencias sociales uno de los problemas que recurrentemente convocan las discusiones entre los epistemólogos es el carácter científico de las ciencias del hombre, a partir de, por un lado, la naturaleza de este tipo de disciplinas por las dificultades de orden teórico-prácticas que tiene el investigador social en su tarea habitual y, por otro lado, en que no puede dejar de involucrarse subjetivamente en ello.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241575,"idioma_id":4,"titulo":"Evolved Distal Tail carbohydrate binding modules of Lactobacillus phage J-1: A novel type of anti-receptor widespread among Lactic Acid Bacteria phages","resumen":"Bacteriophage replication requires specific host-recognition. Some siphophages harbour a large complex, the baseplate, at the tip of their non-contractile tail. This baseplate holds receptor binding proteins (RBPs) that can recognize the host cell-wall polysaccharide (CWPS) and specifically attach the phage to its host. While most phages possess a dedicated RBP, the phage J-1 that infects Lactobacillus casei seemed to lack one. We have shown that the phage J-1 distal tail protein (Dit) plays a role in host recognition and that its sequence comprises two inserted modules compared to ?classical? Dits. The first insertion is similar to carbohydrate-binding modules (CBMs), whereas the second insertion remains undocumented. We determined the structure of the second insertion and found it also similar to several CBMs. We found that expressed insertion CBM2, but not CBM1, binds to L. casei cells and neutralize phage attachment to the bacterial cell wall and that the isolated and purified CWPS of L. casei BL23 prevents CBM2 attachment to the host. Electron microscopy single particle reconstruction of the J-1 virion baseplate revealed that CBM2 is projected at the periphery of Dit to optimally bind the CWPS receptor. Taken together, these results identify J-1 evolved Dit as the phage RBP","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241576,"idioma_id":4,"titulo":"Lactobacillus casei BL23 Produces Microvesicles Carrying Proteins That Have Been Associated with Its Probiotic Effect","resumen":"Archaea, bacteria, and eukarya secrete membrane microvesicles (MVs) as a mechanism for intercellular communication. We report the isolation and characterization of MVs from the probiotic strain Lactobacillus casei BL23. MVs were characterized using analytical high performance techniques, DLS, AFM and TEM. Similar to what has been described for other Gram-positive bacteria, MVs were on the nanometric size range (30?50 nm). MVs carried cytoplasmic components such as DNA, RNA and proteins. Using a proteomic approach (LC-MS), we identified a total of 103 proteins; 13 exclusively present in the MVs. The MVs content included cell envelope associated and secretory proteins, heat and cold shock proteins, several metabolic enzymes, proteases, structural components of the ribosome, membrane transporters, cell wall-associated hydrolases and phage related proteins. In particular, we identified proteins described as mediators of Lactobacillus? probiotic effects such as p40, p75 and the product of LCABL_31160, annotated as an adhesion protein. The presence of these proteins suggests a role for the MVs in the bacteria-gastrointestinal cells interface. The expression and further encapsulation of proteins into MVs of GRAS (Generally Recognized as Safe) bacteria could represent a scientific novelty, with applications in food, nutraceuticals and clinical therapies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241578,"idioma_id":5,"titulo":"Las envolventes constructivas en la construcción no convencional de edificios del nordeste Argentino y el problema de los puentes térmicos","resumen":"Se analizó el comportamiento térmico de las envolventes constructivas de edificios en el Nordeste Argentino (NEA) materializados mediante sistemas constructivos que emplean materiales prefabricados elaborados en serie y mano de obra especializada, atendiendo particularmente al impacto de los puentes térmicos, definidos como 'heterogeneidades' de un elemento constructivo que forman parte de la envolvente (pared, piso, techo, etc.) de un edificio que ocasionan mayor flujo de calor a través de ésta. El objetivo fue diagnosticar y desarrollar criterios de optimización del desempeño energético de estas envolventes. Se estudiaron los tipos y subtipos de construcciones no convencionales y se seleccionaron muestras de aquéllos más empleados en el NEA. Éstas fueron evaluadas con los procedimientos de cálculo establecidos por las Normas IRAM, de la serie 11.600, así como también mediante simulaciones realizadas con el software THERM, un programa de cálculo de transmisión de calor en régimen estacionario, que resuelve numéricamente la ecuación de transmisión de energía en dos dimensiones, en su versión 6.3. La Norma IRAM 11.601 establece el procedimiento de cálculo de manera individualizada de la Transmitancia Térmica Lineal del Muro Opaco (Kmo) y del Puente Térmico (Kpt) y las relaciona para determinar la aptitud del cerramiento. El software THERM, por su lado, calcula la Transmitancia Térmica Total del modelo dibujado. Esto implica que para poder establecerse iguales relaciones deben simularse ambas porciones en modelos separados. Los valores que pudieron obtenerse con ambos procedimientos presentaron discrepancias promedio del 2,6%. Con el software es posible obtener un Coeficiente Ponderado de Transmitancia que incorpora Muro Opaco y Puente Térmico y, con la graficación del flujo de calor a través del cerramiento, reconocer fácilmente los puntos más críticos, para concentrar las acciones de optimización en ellos. THERM resulta por lo tanto un complemento a la normativa, muy útil por la valiosa información gráfica que aporta.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241579,"idioma_id":5,"titulo":"ESTUDIO DE PARÁMETROS INTERPLANETARIOS: SU ALCANCE EN EL ANILLO DE CORRIENTE Y LAS CORRIENTES TELÚRICAS PARA LA TORMENTA DEL 17 DE MARZO DE 2015","resumen":"The interplanetary parameters, corresponding to the period from 16 to 19 March 2015, were analyzed.The parameters considered were Solar wind Plasma speed and flow pressure, Bz and Dst index. The intense solar storm of March 17, 2015, affected the planet generating a potential risk for energy distribution networks, gas pipelines and satellite communications system. The times of growth and decay in the main and recovery phases of the most intense geomagnetic storm corresponding were calculated. By considering geomagnetic values and physical characteristics of the pipeline placed in the zone of Armprior (Canadá), the pipe-soil voltage and the induced currents were determined. The obtained results show that during the disturbed period of the March, 2015, this pipeline would be unprotected and the effects of corrosion originated by the induced currents would diminish its life utility","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241580,"idioma_id":5,"titulo":"EVIDENCIA MAGNÉTICA EN LA PLATAFORMA CONTINENTAL DE ACRECIÓN DEL TERRENO PATAGONIA CON GONDWANA","resumen":"En este trabajo se presentan nuevos datos de anomalías magnéticas totales (TMA) provenientes de estudios oceanográficos y se aplicaron técnicas clásicas de resalto para proporcionar información sobre potenciales suturas entre Patagonia y Sudamérica en la corteza continental. Se reportan los resultados de la aplicación de la señal analítica, el ángulo tilt - en 3D. Con el fin de conocer las profundidades de las fuentes que dan origen a las anomalías, se calculó la deconvolución 2D de Euler y un modelo de inversión gravimétrica 2D en el borde offshore del NE de la Patagonia. Una grilla regular se elaboró con los datos oceanográficos y de grillas globales. El método de la señal analítica mostró un alto contraste entre el cratón del Río de la Plata y el bloque Patagonia, revelando la conexión entre el arco magmático septentrional de la Patagonia, en la corteza continental, con la Zona de Transferencia de Fractura de Colorado en la corteza oceánica; esta característica coincide con el límite NE de la Patagonia. El método de deconvolución de 2D Euler permitió calcular la profundidad de las fuentes de la conspicua anomalía Tona desde 12.000 m a 20.000 m. Un perfil de orientación N-E, basado en un modelo de inversión gravimétrico 2D, permitió la identificación de un cuerpo máfico-ultramáfico en contacto con rocas delbasamento metamórfico a lo largo del borde offshore Patagonia-Gondwana. El ángulo tilt mostró contactos con direcciones diferentes a un lado y al otro del borde NE offshore con Gondwana, denotando una acreción de dos bloques de distinto origen.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241584,"idioma_id":5,"titulo":"Configuraciones orgiástico-literarias del Chelsea Hotel: un espacio queer antes de lo queer","resumen":"Situado en el vértice entre dos décadas (1960-1970) y pensado como un aleph de los itinerarios culturales, el Chelsea Hotel constituye un cruce de coordenadas del ser y el tiempo en donde pudo llegar a materializarse la praxis vital del arte. Lo extenso de la nómina de artistas que produjeron desde o sobre sus confines suele efectuar un progresivo vaciamiento que hace perder de vista la trascendencia y la densidad significativa de esas cristalizaciones de lo que fue un quiebre en el arte y el pensamiento. A partir de una relectura de textos de Patti Smith, Allen Ginsberg y Jack Kerouac, y en consonancia con las producciones de artistas como Warhol o Mapplethorpe, trataremos de desentrañar esa identidad construida a partir de lo transitorio (de la huella imborrable del huésped temporal) que genera el imaginario de un lugar en donde 'todo pasó'. El Chelsea representa un espacio excesivo en donde confluyen cuerpos (humanos y textuales) disidentes en un intercambio orgiástico en el que se diseñan formulaciones marginales de la vida y la literatura en plena corrosión de las normas sexo-genéricas y de afectividad establecidas. Así, se configura no solo como núcleo de la iconoclastia urbana de la Nueva York de esa época, sino como lugar de prefiguración de la potencia subversiva queer.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241586,"idioma_id":5,"titulo":"ESTUDIO DE MEZCLAS DIESEL-BIODIESEL POR REFRACTOMETRÍA EN EL RANGO VISIBLE. APLICACIÓN AL CORTE ARGENTINO","resumen":"En este trabajo se presentan los resultados refractométricos en el rango de luz visible en mezclas diesel-biodiesel. Los ensayos se realizaron de acuerdo a la norma ASTM D1218\/12. Se midieron mezclas preparadas en el laboratorio con 10% de biodiesel y 90% de diesel (B10), correspondiente al corte obligatorio actual utilizado en Argentina, y muestras comerciales de distintos proveedores en un rango de temperatura de 288,15K a 328,15K. El índice de refracción en el rango de luz visible (IRV) para todas ellas muestra una dependencia lineal y decreciente con la temperatura. Por otro lado, se midió el IRV de series de biodiesel con dos tipos de diesel en todo el rango de concentraciones a 313,15K. Se obtuvo una dependencia lineal y decreciente del IRV con el aumento de porcentaje de biodiesel en las series. Los datos experimentales fueron exitosamente ajustados mediante modelos lineales. En todos los casos los coeficientes de determinación fueron mayores a 0,99.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241587,"idioma_id":4,"titulo":"Kinematic viscosity of soybean biodiesel and diesel fossil fuel blends: Estimation from permittivity and temperature","resumen":"Kinematic viscosity and relative permittivity were determined in blends of soybean biodiesel with diesel fossil fuel in the full range of composition at temperatures between 298 K and 318 K (±0.1 K).The kinematic viscosity as a function of temperature fits very satisfactorily to an Arrhenius dependence at all the compositions. The activation energy of this process depends linearly on blend composition. Also, at constant temperature, the kinematic viscosity increases exponentially with biodiesel content.From the analysis of the experimental data, a model is proposed to estimate the kinematic viscosity of blends of unknown composition as a function of permittivity and temperature. Interestingly, the model parameters depend only on the properties of the pure fuels. The fitting to experimental data is very satisfactory; the RMS uncertainty is lower than 0.02 mm2 s&#8722;1.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241589,"idioma_id":5,"titulo":"Efecto de distintos sistemas de producción y formas de sujeción sobre las pérdidas poscosecha en rúcula","resumen":"Manejos adecuados en la producción de rúcula, permitirían incrementar el rendimiento y mantener calidad durante la poscosecha. El trabajo se realizó en la Facultad de Ciencias Agrarias, UNR en tres épocas, con el objetivo de evaluar el efecto de los sistemas de producción en las pérdidas poscosecha. Se analizaron los factores:1) Sistemas de producción: invernadero, malla media sombra, manta flotante y campo, 2) Formas de sujeción: manojo y granel y 3) Días de almacenamientoen cámara frigorífica a 3ºC y 99% H.R. Variables medidas: pérdida de peso por descarte (%), pérdida de peso por agua (%) y color (L*a*b*). El diseño fue DCA en arreglo factorial con 3 repeticiones, ajustando modelo de medidas repetidas en el tiempo con procedimiento MIXED de SAS, incluyendo los efectos de los factores y las interacciones. En pérdida de peso por descarte y por agua hubo interacción entre sistemas de producción y días de almacenamiento en las tres épocas, presentando el invernadero los menoresvalores. En primavera e invierno hubo interacción entre formas de sujeción y días de almacenamiento, mientras que en otoño entre sistemas y formas de sujeción. El atado, produjo menores pérdidas de peso por agua. Manta flotante arrojó el mayor valor de L* para las tres épocas. Para a*, manta flotante y media sombra, en general presentaron menor valor. Para b* los resultados fueron dispares para las tres épocas de cultivo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241590,"idioma_id":5,"titulo":"Mapas conceptuales: herramientas para promover y evaluar aprendizaje significativo","resumen":"Se aborda la potencialidad del uso de los mapas conceptuales en las clases de ciencia con el recurso de la herramienta CmapTools, que se encuentra disponible en las netbooks del Plan Conectar Igualdad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241591,"idioma_id":5,"titulo":"Evaluar para mejorar los programas ¡Pasemos a la acción!","resumen":"La evaluación de programas presenta unaextensa historia de desarrollo teórico, prácticasy discusiones. En los últimos años se han reforzadolas tendencias a comprender el rol estratégicode la evaluación y su incidencia enlos procesos de toma de decisiones.Este trabajo desarrolla ciertos criterios y elementosque conforman una perspectiva integralde la evaluación, poniendo el foco en lacomplejidad de los programas, teniendo encuenta la insuficiencia de los modelos tecnocráticosque desatienden la incidencia de contradiccionesy resistencias de grupos e instituciones.El desarrollo de esta perspectiva integralpretende ser el ?puntapie inicial? de unapropuesta para la práctica real de la evaluación(y el adjetivo no es redundante), entendidadesde la importancia de las estrategiascualitativas y el involucramiento de los diferentesgrupos de personas vinculados con losprogramas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241592,"idioma_id":5,"titulo":"Efecto de distintos sistemas de producción y formas de sujeción sobre las pérdidas poscosecha en rúcula","resumen":"Manejos adecuados en la producción de rúcula, permitirían incrementar el rendimiento y mantener calidad durante la poscosecha. El trabajo se realizó en la Facultad de Ciencias Agrarias, UNR en tres épocas, con el objetivo de evaluar el efecto de los sistemas de producción en las pérdidas poscosecha. Se analizaron los factores:1) Sistemas de producción: invernadero, malla media sombra, manta flotante y campo, 2) Formas de sujeción: manojo y granel y 3) Días de almacenamientoen cámara frigorífica a 3ºC y 99% H.R. Variables medidas: pérdida de peso por descarte (%), pérdida de peso por agua (%) y color (L*a*b*). El diseño fue DCA en arreglo factorial con 3 repeticiones, ajustando modelo de medidas repetidas en el tiempo con procedimiento MIXED de SAS, incluyendo los efectos de los factores y las interacciones. En pérdida de peso por descarte y por agua hubo interacción entre sistemas de producción y días de almacenamiento en las tres épocas, presentando el invernadero los menoresvalores. En primavera e invierno hubo interacción entre formas de sujeción y días de almacenamiento, mientras que en otoño entre sistemas y formas de sujeción. El atado, produjo menores pérdidas de peso por agua. Manta flotante arrojó el mayor valor de L* para las tres épocas. Para a*, manta flotante y media sombra, en general presentaron menor valor. Para b* los resultados fueron dispares para las tres épocas de cultivo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241596,"idioma_id":4,"titulo":"Publish (in English) or perish: The effect on citation rate of using languages other than English in scientific publications","resumen":"There is a tendency for non-native English scientists to publish exclusively in English, assuming that this will make their articles more visible and cited. We tested this hypothesis by comparing the effect of language, on the number of citations of articles published in six natural sciences journals from five countries that publish papers in either English or other languages. We analyzed the effect of language (English vs non-English), paper length and year of publication on the number of citations. Articles published in English have a higher number of citations than those published in other languages when the effect of journal, year of publication and paper length are statistically controlled. This may result because English articles are accessible to a larger audience, but other factors need to be explored. Universities and scientific institutions should be aware of this situation and improve the teaching of English, especially in the natural sciences.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241597,"idioma_id":4,"titulo":"Daily activity pattern of reintroduced giant anteaters (Myrmecophaga tridactyla): effects of seasonality and experience","resumen":"We assessed the effect of seasonality and intrinsic conditions on daily activity pattern of giant anteaters reintroduced in the Iberá Reserve, Argentina. During 2007-2012 we gathered 159 24-h focal samples on 15 radio-marked individuals (11 captive-reared, four wild-reared; seven adults, eight juveniles), 216 records of beginning and end of activity bouts on 20 individuals, and 454 camera-traps records (3,345 trap-days). We estimated the daily hours of activity, the percentage of diurnal and nocturnal activity, and the daily activity range and time overlap using time as a circular variable in kernel density estimations. We assessed differences between seasons, sexes, age classes, and types of rearing. The average daily hours of activity was 8:43 h. Camera-traps and radio-telemetry showed similar results. Animals exhibited both diurnal (60-65%) and nocturnal (40-35%) activity. The higher probability for being active ranged within 09:00-03:00 h. Anteaters spent more hours active and were more nocturnal during summer. Activity was highly overlapped between sexes and wild reared individuals were more nocturnal than captive-reared ones. Seasonal shifts in daily activity highlights the importance of thermoregulation as a selective factor in this species. The giant anteater is a cathemeral species with flexibility to accommodate its activity pattern to local conditions or experience.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241598,"idioma_id":4,"titulo":"Habitat selection and home range use by resident and reintroduced giant anteaters in two South American wetlands","resumen":"One of the benefits of modeling habitat selection for a given population is the ability to predict patterns in another population that inhabits an ecologically similar area. We studied habitat selection and home ranges of reintroduced and wild giant anteaters (Myrmecophaga tridactyla) in 2 South American wetlands (Iberá, Argentina, and Pantanal, Brazil). Nine reintroduced (Iberá) and 10 wild (Pantanal) adult animals were tracked via VHF and GPS between 2007 and 2015. We used resource selection functions to assess habitat selection for the wild anteaters from Pantanal. Generalized lineal mixed models were constructed for resting and activity periods during both the wet and dry seasons. We then validated previous models built for reintroduced anteaters in Iberá using data from the wild animals from Pantanal. Habitat type (floodplain, grassland, open savanna, closed savanna, and forest) and distances to selected landscape traits were used as covariates. Locations near forests were positively selected in both populations. Selection of forests in Pantanal was less evident than in Iberá, probably due to the much higher availability of forests in the Brazilian site, with 38?53% of the landscape classified as good-to-high likelihood in Pantanal compared to only 4% in Iberá. Mean home range size of males was larger in Iberá (32.50 ± 7.64 km2) than in Pantanal (14.07 ± 1.97 km2), whereas home range sizes of females were similar in both areas (9.75 ± 1.74 km2 in Iberá; 9.62 ± 2.00 km2 in Pantanal). Results of this study suggest that model validation with geographically independent data is a useful tool to compare reintroduced and wild populations and to identify resources or landscape attributes that are important for a given species, even when these resources are abundant or highly available. RESUMENUna de las posibles ventajas de modelar la selección de hábitat de una población es la posibilidad de predecir patrones en otra población que habita un área ecológicamente similar. Se estudió la selección de hábitat y las áreas de acción de osos hormigueros (Myrmecophaga tridactyla) reintroducidos y silvestres en dos humedales sudamericanos (Iberá, Argentina, y Pantanal, Brasil). Se monitorearon 9 osos hormigueros adultos reintroducidos (Iberá) y 10 silvestres (Pantanal) a través de VHF y GPS entre 2007 y 2015. Se utilizaron funciones de selección de recursos para evaluar la selección de hábitat de los animales silvestres del Pantanal. Modelos lineales generalizados mixtos fueron construidos para los períodos de descanso y actividad y para las estaciones húmeda y seca. Los modelos previamente construidos para los animales reintroducidos en Iberá, fueron validados con los datos de los animales no translocados del Pantanal. Se utilizaron el tipo de hábitat (planicie de inundación, pastizal, sabana, bosque abierto y bosque continuo) y las distancias a características del paisaje seleccionadas como variables explicativas. Los sitios cercanos a bosques fueron seleccionados positivamente en ambas poblaciones. La selección de bosques por los animales del Pantanal fue menos evidente que la de los animales de Iberá, probablemente debido a la mayor disponibilidad de bosques en el primer sitio, con un 38?53% del paisaje clasificado como de buena?alta probabilidad de ocurrencia en el Pantanal, comparado con sólo el 4% en Iberá. El tamaño promedio de las áreas de acción de los machos fue mayor en Iberá (32.50 ± 7.64 km2) que en el Pantanal (14.07 ± 1.97 km2), mientras que los tamaños de las áreas de acción en las hembras fueron similares (9.75 ± 1.74 km2 en Iberá; 9.62 ± 2.00 km2 en Pantanal). Los resultados de este estudio sugieren que la validación de modelos con datos geográficamente independientes es una herramienta útil para comparar poblaciones reintroducidas y silvestres y para identificar recursos o atributos del paisaje que son importantes para una especie, aun cuando estos recursos sean abundantes o estén altamente disponibles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241599,"idioma_id":4,"titulo":"Assessing global patterns in mammalian carnivore occupancy and richness by integrating local camera trap surveys","resumen":"Aim:  Biodiversity loss is a major driver of ecosystem change, yet the ecological data required to detect and mitigate losses are often lacking.  Recently, camera trap surveys have been suggested as a method for sampling local wildlife communities as these observations can be collated into a global monitoring network.  To demonstrate camera traps? potential for global monitoring, we assembled data from multiple, local camera trap surveys to evaluate the interchange between fine- and broad-scale processes impacting mammalian carnivore communities.  Location: Argentina, Belize, Botswana, Canada, Indonesia, Iran, Madagascar, Nepal, Norway, Senegal, South Africa, and the United States.Methods:  We gathered camera trap data, totaling >100,000 trap nights, from across 5 continents.  To analyze local and species-specific responses to anthropogenic and environmental variables, we fit multi-species occurrence models to each study area. To analyze global-level responses, we then fit a multi-species, multi-area occurrence model. Results:  We recorded 4,805 detections of 96 mammalian carnivore species photographed across 1,714 camera stations located in 12 countries.  At the global-level, our models revealed that carnivore richness and occupancy within study areas was positively associated with prey availability.  Occupancy within study areas also tended to increase with greater protection and greater distances to roads.  The strength of these relationships, however, differed among countries. Main conclusions:  We developed a research framework for leveraging global camera trap data to evaluate patterns of mammalian carnivore occurrence and richness across multiple spatial scales.  Our research highlights the importance of intact prey populations and protected areas in conserving carnivore communities.  Our research also highlights camera traps? potential for monitoring wildlife communities and provides a case study for how this can be achieved on a global scale.  We encourage greater integration and standardization among camera trap studies worldwide, which would help inform effective conservation planning for wildlife populations both locally and globally.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241600,"idioma_id":4,"titulo":"The Giant Armadillo (Priodontes maximus) in the Argentine Chaco","resumen":"The giant armadillo (Priodontes maximus) is a difficult species to study because of low population densities, combined with nocturnal and fossorial habits. No systematic population studies have been undertaken to date in Argentina. Our objectives were to evaluate the species? presence, relative abundance, and temporal activity patterns across five locations with different levels of human disturbance and legal protection in the Argentine Chaco. Between June 2006 and January 2014, we completed 10 surveys, using camera trap and \/ or track plots, searches for burrows and tracks, and observations by local people and park rangers. We used camera trap records to determine presence, relative abundance (records \/ 100 camera days) and activity patterns. We only recorded the species at three locations: Copo National Park, Aborigen Reserve and La Fidelidad Resource Reserve. At the Aborigen Reserve we documented burrows and tracks but obtained no photographs. At Copo and La Fidelidad we estimated relative abundance at 0.08 and 0.40 records per 100 camera days, respectively. We did not record giant armadillos near the edges of La Fidelidad, nor in the two locations with greater human disturbance. Camera trap records indicate that giant armadillos in the Argentine Chaco are strongly nocturnal. The population status of giant armadillos in Argentina is a matter of concern. With few or no records at other study locations, La Fidelidad may harbor one of the few relict populations of giant armadillos in the Argentine Chaco.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241601,"idioma_id":4,"titulo":"Experimental testing of reciprocal effects of nutrition and parasitism in wild black capuchin monkeys","resumen":"Nutritional stress may predispose individuals to infection, which in turn can have further detrimental effects on physical condition, thus creating an opportunity for reciprocal effects between nutrition and parasitism. Little experimental investigation has been conducted on this ?vicious circle? hypothesis in wild animals, especially under natural conditions. We evaluated the reciprocal effects of nutritional status and parasitism using an experimental approach in two groups of wild black capuchin monkeys (Sapajus nigritus). Across two consecutive winters, we collected faecal samples from identified capuchins to determine presence and load of gastrointestinal helminthes, and measured individual body mass as a proxy of physical condition. Food availability was manipulated by provisioning monkeys with bananas, and parasite burdens by applying anti-parasitic drugs to selected individuals. We found no effect of anti-parasitic drugs on physical condition, but parasite loads decreased in response to high levels of food availability. Our results represent the first experimental evidence that the nutritional status may drive parasite dynamics in a primate.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241602,"idioma_id":4,"titulo":"ATLANTIC-CAMTRAPS: a dataset of medium and large terrestrial mammal communities in the Atlantic Forest of South America","resumen":"Our understanding of mammal ecology has always been hindered by the difficulties of observing species in closed tropical forests. Camera trapping has become a major advance for monitoring terrestrial mammals in biodiversity rich ecosystems. Here we compiled one of the largest datasets of inventories of terrestrial mammal communities for the Neotropical region based on camera trapping studies. The dataset comprises 170 surveys of medium to large terrestrial mammals using camera traps conducted in 144 areas by 74 studies, covering six vegetation types of tropical and subtropical Atlantic Forest of South America (Brazil and Argentina), and present data on species composition and richness. The complete dataset comprises 53,438 independent records of 83 species of mammals, includes 10 species of marsupials, 15 rodents, 20 carnivores, 8 ungulates and 6 armadillos. Species richness averaged 13 species (± 6.07 SD) per site. Only six species occurred in more than 50% of the sites: the domestic dog Canis familiaris, crab-eating fox Cerdocyon thous, tayra Eira barbara, south American coati Nasua nasua, crab-eating raccoon Procyon cancrivorus and the nine-banded armadillo Dasypus novemcinctus. The information contained in this dataset can be used to understand macroecological patterns of biodiversity, community, and population structure, but also to evaluate the ecological consequences of fragmentation, defaunation, and trophic interactions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241605,"idioma_id":4,"titulo":"BINDING OF PLANT LECTINS BY DAIRY PROPIONIBACTERIA MAY DECREASE THEIR DELETERIOUS EFFECTS ON COLONIC PHYSIOLGY","resumen":"Plant lectins are specific carbohydrate-binding proteins widespread in legumes like beans and pulses, seeds, cereals, and many plants used as farm feeds. They are highly resistant to cooking and digestion, reaching to the intestinal lumen and\/or blood circulation with biological activity. As result, a series of harmful local and systemic reactions are triggered placing these molecules as antinutritive and\/or toxic substances. In the gut, specific cell receptors and microbiota may interact with these dietary components leading to changes on intestinal physiology. It has been proposed that probiotic microorganisms with suitable surface glycosidic moieties could bind to dietary lectins favoring their elimination from the intestinal lumen or inhibiting their interaction with epithelial cells. In this work, we assessed in vitro the effects of two representative plant lectins, concanavalin A (Con A) and jacalin (AIL) on proliferation of SW480 colonic adenocarcinoma cell line and metabolic activity of colonic microbiota in the absence or presence of Propionibacterium acidipropionici CRL 1198. Both lectins induced proliferation in a dose-dependent manner of colonic cell line whereas ConA inhibited fermentative activities of colonic microbiota being these effects prevented to different extents by the presence of propionibacteria. The observed effects could be ascribed to binding of lectins by bacterial cells since P. acidipropionici CRL 1198 was unable to metabolize these proteins and its adhesion to colonic cells was reduced after reaction with Con A or AIL. Results suggest that consumption of propionibacteria at the same time than lectins could reduce the incidence of lectins-induced alterations in the gut and may be a tool to protect the intestinal physiology.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241608,"idioma_id":5,"titulo":"El escenario de  compleja oportunidad, que plantea la ecuación: demanda de cualidades por parte de las organizaciones - la oferta de capacidades de los jóvenes profesionales en Ciencias Económicas de la ciudad de Rosario.","resumen":"El artículo, intenta analizar cómo se articula la relación entre los jóvenes profesionales en Ciencias Económicas y las distintas organizaciones en  donde  se desempeñarán como profesionales, ante las nuevas realidades: complejidad, competitividad extrema, variaciones de variables de determinación, contexto con mayor grado de implicancia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241609,"idioma_id":4,"titulo":"Molecular identification and technological characterization of lactic acid bacteria isolated from fermented kidney beans flours (Phaseolus vulgaris L. and P. coccineus) in northwestern Argentina","resumen":"Legumes are an important protein source in developing countries and their flours represent an attractive alternative for the manufacture of gluten free products. In the present study, 4 kidney bean varieties (Alubia, Pallar, Black and Red beans) commonly cultivated in northwestern Argentina, were milled and spontaneously fermented in order to isolate and select autochthonous lactic acid bacteria (LAB) with relevant technological and functional properties for usage as starter cultures. Twelve doughs were fermented with daily back-slopping at 37°C for 6days and evolution of total mesophiles, lactic acid bacteria, and yeasts and molds populations were followed by plate counting. A combination of phenotypic and genotypic methods including (GTG)5-based PCR fingerprinting and 16S rRNA gene sequencing were used to differentiate and identify the isolated LAB to species level. LAB counts ranged from around 0.89±0.81 to 8.74±0.03logcfu\/g with a pH decline from 6.4 to 3.9 throughout fermentation. Four genera and nine species of LAB: Enterococcus durans, E. faecium, E. mundtii, E. casseliflavus; Lactobacillus rhamnosus, Lactococcus garvieae, Weissella cibaria and W. paramesenteroides were found on kidney beans. Twenty five LAB strains were assessed for their abilities to grow on kidney bean extracts, acidifying capacities (pH and acidification rates), amylolytic, proteolytic, tannase and gallate decarboxylase activities as well as pathogens inhibition by antimicrobials. Based on these properties E. durans CRL 2178 and W. paramesenteroides CRL 2182 were inoculated singly and combined in Alubia kidney bean flour and fermented for 24h at 37°C. LAB strains were beneficial for removing trypsin inhibitors and tannins from sourdoughs and for improving amino acids and phenolics contents, increasing the antioxidant activities of kidney bean matrices. Selected strains have potential as starter cultures for obtaining fermented bean products with high nutritional and functional quality.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241610,"idioma_id":5,"titulo":"La interrelación de los recursos, clave de la competitividad interna","resumen":"El presente trabajo, se enfoca en dos aspectos:Primero: el estudio de la gestión de los recursos  como instrumento para construir una ventaja competitiva.Segundo.  El impacto del apalancamiento de los recursos sobre la competitividad de la empresa, será determinante, en la medida que el apalancamiento no sea el resultado de un movimiento pendular sino de una decisión empresarial.Las PyMEs, constituyen un entramado social y económico fuerte en un contexto de altos cambios, los que hoy le proporcionan más oportunidades que amenazas, por su estructura flexible, por su conciencia de crisis, y  por las políticas gubernamentales que desde hace más de 15 años, comenzaron a considerarlas como un sector de la economía sustentable.Sin embargo, no podemos dejar de considerar que las pequeñas y medianas empresas, enfrentan grandes desafíos como la competencia de las corporaciones.Estos retos si son adecuadamente gestionados, impactarán positivamente en su rentabilidad, en sus variables de sobrevivencia y mucho más en su crecimiento sostenido.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241611,"idioma_id":5,"titulo":"Del aborto no punible a la interrupción legal del embarazo","resumen":"El presente trabajo se enmarca en el Proyecto de Investigación V094 ?Los padecimientos actuales en las infancia\/s y adolescencia\/s. El lugar de los abordajes institucionales: el trabajo comunitario ante lo que resiste?, dirigido por la Dra. Patricia Weigandt y codirigido por la Prof. y Lic. Marina La Vecchia, del Centro Universitario Regional Zona Atlántica (CURZA). Nuestro trabajo tiene un doble propósito. Intenta, por un lado, visibilizar un derecho oculto en la ley: el derecho a la interrupción legal del embarazo o aborto nopunible. Y por otro, interpelar sobre el proceso de constitución subjetiva que posibilita el advenimiento en sujeto. El conjunto de normas nacionales e internacionales serán las coordenadas que nos guiarán a lo largo de este recorrido para advertir sobre la legalización de lo ilegal en las prácticas institucionales sobre el aborto no punible. Asimismo, tomaremos los aportes del marco teórico psicoanalítico a fin de poner en cuestión el estatuto de las funciones de hijo\/a y de madre y diferenciarlas con la letra del discurso deinstituciones judiciales, de salud y mediáticas que vulneran los Derechos Humanos al violentar, judicializar y criminalizar a la mujer en situación de aborto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241612,"idioma_id":5,"titulo":"Ni tres menos: cuando el Estado es el feminicida","resumen":"El presente trabajo intenta por un lado, una aproximación teórica a la construcción de los conceptos femicidio y feminicidio, así como pretende reflexionar acerca del impacto que tiene en la comunidad la utilización de estos términos en las realidades concretas de las mujeres. Las conceptualizaciones y recorridos realizados por la antropóloga Marcela Lagarde se tornan fundamentales en tanto acuñó el concepto feminicidio y visibilizó de esta manera la responsabilidad política que le caben a los Estados (y sus instituciones) respecto a los asesinatos de las mujeres, producto de su inactividad y complicidad con un sistema que históricamente desfavoreció a las mujeres mediante diversos mecanismos de poder y opresión. Por otro lado, y en función de la categoría feminicidio, se realiza un contraste entre dos estadísticas de feminicidios del año 2015 en Argentina y Río Negro, que muestran dos realidades absolutamente diferentes pese a recortar el mismo período de análisis. Se trata del Observatorio Adriana Marisel Zambrano de la Asociación Civil la Casa del Encuentro, y el Registro de Femicidios de la Justicia Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241618,"idioma_id":5,"titulo":"Changes in the business model for Spanish fresh tomato trade","resumen":"The business model applied to the fresh tomato trade from Almería is well known in Spain and abroad. The changes in demand are forcing export companies to change their trade strategies to become or remain competitive. The purpose of this paper is to know the business structure and its export dynamics in addition to the changes in trade strategies made by companies in Almería during the 2009-2013 period. The methodology is based on the Herfindahl-Hirshman index and the foreign trade competitiveness index, whereas the congruence analysis is based on Pearson?s correlation coefficients and the RV coefficient. We have also applied the dual multiple factor analysis to verify changes made to the trade policy in leading businesses between two periods or scenarios. The research shows that export-driven companies behave as a moderately concentrated structure and there is an increase in the number of exporters. The competitiveness map for Almería reveals the sector?s trend with regard to the most important markets. We have verified the changes made to their trade strategy to adjust to changes in foreign trade between the 2008\/09 and 2012\/13 campaigns. Finally, it can be pointed out that, in the analyzed period, changes in the business model for fresh tomato trade of Almería have not been significant, being its structure of moderate concentration. In addition, the great majority of variations in strategies of companies to adapt to the competitive environment have been made by leading companies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241620,"idioma_id":5,"titulo":"Alfabetización académica en entornos virtuales: Estrategias para la promoción de la escritura de la tesis de posgrado","resumen":"Se comunica una investigación-acción a partir de la cual se diseña, implementa, evalúa y ajusta un taller totalmente virtual que se orientó a promover la producción de un capítulo escrito por el alumno como parte de sus estudios de posgrado con una perspectiva que articula las siguientes dimensiones: lingüístico-discursiva, cognitiva, psicopedagógica y tecnológica. En una secuencia didáctica de once semanas, en cada una se aborda un tema (géneros académico-científicos, marco teórico y citación, metodología, presentación de los resultados, conclusiones, introducción, entre otros) a través de actividades individuales y\/o colectivas con apartados de tesis auténticas. Participan doctorandos de Ciencias Sociales y Humanas de diferentes universidades argentinas. Al finalizar el taller, los alumnos disponen de un mes para producir un Traslaciones. Revista Latinoamericana de Lectura y Escritura, 4 (8) Hilda Difabio de Anglat y Guadalupe Álvarez 98 capítulo de su tesis, el que opera como evaluación final, proceso que es apoyado mediante un documento en Googledocs o en Moodle para cada doctorando al que tuvo acceso junto con las docentes. Las apreciaciones de los alumnos permiten deducir que la valoración general es positiva; además, evidencian un incremento afín con el nivel de partida en estrategias de escritura y su regulación, la concepción de la labor escritural como elaboración, sentimientos de autoeficacia como escritor y competencia autopercibida para la escritura académica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241621,"idioma_id":5,"titulo":"Cambios en el modelo del comercio internacional del piña en Costa Rica","resumen":"Costa Rica es el principal exportador mundial de piña en fresco. Desde hace unos años se aprecia cómo los factores de la demanda de estos productos están variando y por lo tanto es necesarios conocer si las empresas comercializadoras se están adaptando a la demanda. El objetivo de este artículo es analizar el modelo de la piña de este país desde una tripe pesrsectiva: estructura empresarial del sector, dinámica del comercio internacional y estrategias comerciales de los exportadores. Como conclusión se puede señalar que la estructura organizacional se caracteriza por una baja concentracioón económica y una estrategia comercial de las empresas de exportación muy dinámicas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241622,"idioma_id":4,"titulo":"The low affinity neurotensin receptor antagonist levocabastine impairs brain nitric oxide synthesis and mitochondrial function by independent mechanisms.","resumen":"Neurotensin is known to inhibit neuronal Na+, K+ -ATPase, an effect that is rescued by nitric oxide (NO) synthase inhibition. However, whether the neurotensinergic and the nitrergic systems are independent pathways, or are mechanistically linked, is unknown. Here, we addressed this issue and found that the administration of NTS2 antagonist, levocabastine (50 &#956;g\/kg, i.p.) inhibited NO synthase (NOS) activity by 74 and 42% after 18 h in synaptosomal and mitochondrial fractions isolated from the Wistar rat cerebral cortex, respectively; these effects disappeared 36 h after levocabastine treatment. Intriguingly, whereas neuronal NOS (nNOS) protein abundance decreased (by 56%) in synaptosomes membranes, it was enhanced (by 86%) in mitochondria 18 h after levocabastine administration. Levocabastine enhanced the respiratory rate of synaptosomes in the presence of oligomycin, but it failed to alter the spare respiratory capacity; furthermore, the mitochondrial respiratory chain (MRC) complexes I-IV activities were severely diminished by levocabastine administration. The inhibition of NOS and MRC complexes activities were also observed after incubation of synaptosomes and mitochondria with levocabastine (1 &#956;M) in vitro. These data indicate that the NTS2 antagonist levocabastine regulates NOS expression and activity at the synapse, suggesting an interrelationship between the neurotensinergic and the nitrergic systems. However, the bioenergetics effects of NTS2 activity inhibition are likely to be independent from the regulation of NO synthesis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241627,"idioma_id":4,"titulo":"AN INTEGRATED PHYSICAL MAP OF THE CULTIVATED HOT CHILI PEPPER CAPSICUM BACCATUM VAR. PENDULUM (SOLANACEAE)","resumen":"Capsicum baccatum var. Pendulum is the most frequently cultivated chili pepper in South America. This taxon is an outstanding source for breeding programs for genetic improvement in the genus, since its traits can be introgressed into C. annuum and related species to generate viable hybrids. In this study, the chromosome complement of C. baccatum var. Pendulum 2n = 24 was deeply characterized through a sequential combination of conventional and molecular cytogenetics approaches comprising Ag-NOR staining, heterochromatic fluorescence C-DAPI and CMA\/DA\/DAPI bandings and fluorescent in situ hybridization (FISH) of Capsicum-derived 5S and 18S-25S ribosomal genes and spacers probes. The attained markers were systematically integrated into a physical map which allows the identification of each individual chromosome. This is the first integrated physical map of C. baccatum var. Pendulum which, in conjunction with reported genetic linkage maps of Capsicum, would be useful for future high-density genetic mapping and whole-genome studies in C. baccatum and related taxa, as well as in breeding and genetic improvement programs in chili peppers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241628,"idioma_id":4,"titulo":"Dataset of the transcribed 45S ribosomal RNA sequence of the tree crop ?yerba mate?","resumen":"This contribution contains data related to the research article entitled 'The 18S-25S ribosomal RNA unit of yerba mate (Ilex paraguariensis A. St.-Hil.)' [1]. Through a bioinformatic approach involving NGS data, we provide information of the transcribed 45S ribosomal RNA (rRNA) sequence of yerba mate, the first reference for the Ilex L. genus. This dataset (Supplementary file 1) comprises information regarding the assembly and annotation of this rRNA unit. The generated data is applicable for comparative analysis and evolutionary studies among Ilex and related taxa. The raw sequencing data used here is available at DDBJ\/EMBL\/GenBank [2] Sequence Read Archive (SRA) under the accession SRP043293 and the consensus 45S ribosomal RNA sequence has been deposited there under the accession GFHV00000000.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241631,"idioma_id":4,"titulo":"Sedimentation analysis of small ice crystals by Lattice Boltzmann Method","resumen":"Lattice Boltzmann Method (LBM) is used to simulate and analyze the sedimentation of small (15&#8201;&#8722;&#8201;80&#8201;&#956;m) columnar ice particles in the atmosphere. We are specially interested in evaluating the terminal falling velocity of columnar ice crystals with hexagonal cross section. The main objective is to apply the LBM to solve ice crystal sedimentation problems. This numerical method is evaluated as a powerful numerical tool to solve ice crystal sedimentation problems in a variety of sizes. LBM results are presented in comparison with laboratory experimental results and theoretical approaches well known in the literature. The numerical results show good agreement with experimental and theoretical results for the analyzed geometrical configurations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241634,"idioma_id":4,"titulo":"Systemic effects of Subtilase cytotoxin produced by Escherichia coli O113:H21","resumen":"Subtilase cytotoxin (SubAB) is a member of the AB5 cytotoxin family and is produced bycertain strains of Shiga toxigenic Escherichia coli. The toxin is known to be lethal to mice,but the pathological mechanisms that contribute to Uremic Hemolytic Syndrome (HUS)are poorly understood. In this study we show that intraperitoneal injection of a sublethaldose of SubAB in rats triggers a systemic response, with ascitic fluid accumulation, hearthypertrophy and damage to the liver, colon and kidney. SubAB treated rats presentedmicroalbuminuria 20 days post inoculation. At this time we found disruption of theglomerular filtration barrier and alteration of the protein reabsorption mechanisms of the&nbsp;proximal tubule. In the kidney, SubAB also triggered an epithelial to mesenchymaltransition (1). These findings indicate that apart from direct cytotoxic effects on renaltissues, SubAB causes significant damage to the other organs, with potentialconsequences for HUS pathogenesis.Importance: Uremic Hemolytic Syndrome is an endemic disease in Argentina, with over400 hundred new cases each year. We have previously described renal effects of ShigaToxin and its ability to alter renal protein handling. Bearing in mind that SubtilaseCytotoxin is an emerging pathogenic factor, that it is not routinely searched for in patientswith HUS, and that to the date its systemic effects have not been fully clarified we decidedto study both its systemic effects, and its renal effects to assess whether SubAB could becontributing to pathology seen in children.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241638,"idioma_id":5,"titulo":"José León Pagano: realismo e idealismo en la estética renacentista, en Boletín de estética. Programa de estudio en filosofía del arte. Centro de investigaciones filosóficas","resumen":"En el presente trabajo nos proponemos desarrollar la concepción  que  José León Pagano, esteta, historiador del arte y pintor argentino del siglo XX, construye sobre la manifestación artística y filosófica en el Renacimiento italiano. Para Pagano, dicho período  preconiza el retorno  a la naturaleza y, así, se genera el nacimiento de una nueva sensibilidad estética, deviniendo en un realismo artístico que se contradice, a su vez, con un idealismo neoplatónico. Nuestro propósito en este trabajo es reconstruir la tesis de Pagano sobre la  oposición entre realismo e idealismo en su análisis de la relación entre neoplatonismo y arte florentino","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241639,"idioma_id":5,"titulo":"Aplicación de herramientas multimediales colaborativas para la generación de contenidos digitales destinados a la educación secundaria","resumen":"En este trabajo se presentan algunos avances de un proyecto de investigación y desarrollo que se articula entre la Facultad Regional Rafaela de la Universidad Tecnológica Nacional y el Instituto Superior del Profesorado N° 2 de la ciudad de Rafaela dentro de una convocatoria de la Secretaría de Ciencia y Tecnología de la provincia de Santa Fe, y que todavía continua.El hecho de haber podido concretar acciones conjuntas de trabajo que tengan como objetivo la incorporación de herramientas colaborativas multimediales que favorezcan el aprendizaje de las ciencias fue en sí mismo un desafío y constituye un hecho novedoso para ambas instituciones educativas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241647,"idioma_id":5,"titulo":"Revisión operativa y ambiental de las plantas de ósmosis inversa de la Provincia de La Rioja, Argentina.","resumen":"Un estudio realizado a pedido del instituto Provincial del Agua de La Rioja, recomienda a este la revisión operativa de sus plantas de ósmosis inversa, teniendo en cuenta los aspectos ambientales de su funcionamiento.Este grupo se ha abocado a la tarea habiendo realizado hasta este momento el relevamiento de la totalidad de estas plantas y ha zonificado el estudio según un criterio de circuitos viales a recorrer, para optimizar los tiempos de visita y recolección de datos.Se ha evaluado la situación operativa de tres plantas del sur de la provincia.  Se recomienda hasta el momento un procedimiento para la operación de cada planta revisada  y realizar el tratamiento de las aguas de rechazo, que hasta el momento se vierten en las inmediaciones. El contenido salino varía en cantidad y calidad.Por el momento se  recomienda el tratamiento de las aguas de rechazo por evaporación y la disposición final de los productos, en este caso en las salinas del sur, límite de La Rioja con San Juan.  La composición de las sales se asemeja a las que se emplean en los suplementos dietarios del ganado. Una alternativa para la disposición de las sales es el aprovechamiento de estas sales para la fabricación de los panes que emplean en  la dieta en  ganadería, una actividad importante para la economía de la provincia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241649,"idioma_id":5,"titulo":"Reivindicar la dignidad de las viviendas de madera","resumen":"Construir en material? El patrimonio no monumentalPor Dra. Arq. Graciela de Kuna ?Próximamente comenzaremos a construirla en material?, les respondió a los alumnos de arquitectura que la entrevistaban, la dueña de una casita de madera, de las pocas que quedan en la ciudad?Materializada mediante el sistema de tablón y tapajuntas, es decir con grandes tablas de madera dura, de dimensiones nunca después vistas, dispuestas a tope y listones del mismo material a lo largo de sus uniones verticales; en algunos casos con mejoras en la materialidad de la techumbre por estar más expuesta, estas deliciosas casitas que quedan de la primera consolidación de Posadas, mensurada en 1871 por el agrimensor Lezcano, quien también lo hará con Resistencia, Chaco. Con un desarrollo básicamente de casitas bajas como ésta en dónde comenzaban a construirse una serie de casonas de ladrillos asentados en barro con techo de grandes vigas terminadas a hachuela, que sostenían los ladrillones (ladrillos de mayores dimensiones de alto y ancho y menor espesor) que recibían una capa de compresión y unificación con terminación de tejas canal. En ese tiempo perteneciente al Territorio Nacional, con su antigua capital en Candelaria a unos 20kms de Posadas, la actual capital de la Provincia de Misiones tenía un puerto natural que proveyó a la ciudad del incremento en la calidad de vida que mejorara aquel sistema constructivo basado exclusivamente de elementos naturales, entre ellos la madera. Ello da cuenta, además de la gran disposición de ?buena madera? que había en el interior, con obrajes montados en el medio de las porciones naturales de selva, proveedoras de maderas riquísimas de diversa índole, muchas de ellas, actualmente están en el inventario de especies protegidas del patrimonio natural de la provincia. Profundamente ligada a esta explotación está la vida del Mensú, jornalero de la extracción de madera nativa, cuya paga en forma de vales, era sólo canjeable en los ?boliches? de la misma compañía que les pagaba y que en sus días francos bajaban con el río hacia el espacio fundacional de la ciudad de Posadas, llamada la Bajada Vieja que serpentea desde la altura de la barranca hacia el antiguo puerto sobre el río Paraná, actualmente desaparecido bajo al aguas del embalse de Yacyretá. ¿Qué quiso decir la señora? Es común plantear el tema constructivo en estos términos, generalmente la gente no considera a la madera un material digno de ser utilizado como conformante de su vivienda, ligándola en su imaginario a la representación de pobreza.Pero es qué ¿acaso la madera no es un material apto para construir? La madera es quizás uno de los más nobles y propicios para climas rigurosos, ya que es de los menos permeables al paso del calor o el frío del exterior al interior y por eso de los que mejor conserva la temperatura. En USA la mayoría de las mansiones y casas en general están hechas en madera, el sistema constructivo que permitió la expansión hacia el oeste y su conquista, el ballon frame. Sistematizado a tal punto que en cualquier almacén de ramos generales se encontraban y se encuentran los listones, ya cortados en las escuadrías necesarias para su utilización. ¿Quién no ha visto alguna película norteamericana en dónde, todo el pueblo solidariamente contribuye en la construcción de una vivienda de este tipo?El otro sistema, aquel de ladrillos asentados en barro, ha dado en Posadas también, ejemplos magníficos que nos hablan de otra manera de concebir la vida y el transcurrir y que también se encuentran en peligro, el caso es la casona que actualmente se encuentra al borde de ser destruida por la piqueta el ?Residencial Misiones, un histórico edificio que está considerado un espacio de interés cultural y patrimonial?, según diarios locales.    Actualmente, la UNESCO, organismo internacional destinado a la educación y dependiente de la ONU (Organización de Naciones Unidas), propone en su Carta del Patrimonio Vernáculo (es decir el doméstico, nativo, de nuestra casa o país, según la Real Academia Española: www.rae.es), la preservación y conservación de esos bienes que dan cuenta de formas específicas de producción de significados a partir de los usos y costumbres tradicionales de cada lugar y que por supuesto, no corresponden al llamado patrimonio monumental, y además propone medidas para conservarlos como verdaderos rasgos de identidad de los pueblos, de sus relaciones con el territorio y al mismo tiempo, la expresión de la diversidad cultural del mundo. La carta, de 1999, en su Consideraciones Generales, plantea que Los ejemplos de lo vernáculo pueden ser reconocidos por: a) Un modo de construir emanado  de la propia comunidad.b) Un reconocible carácter local o regional ligado al territorio.c) Coherencia de estilo, forma y apariencia, así como el uso de tipos arquitectónicos tradicionalmente establecidosd) Sabiduría tradicional en el diseño y en la construcción, que es trasmitida de manera informal.e) Una respuesta directa a los requerimientos funcionales, sociales y ambientales.f) La aplicación de sistemas, oficios y técnicas tradicionales de construcción. Y en ese sentido, tenemos un extenso patrimonio tradicional o vernáculo, arraigado en nuestra identidad más profunda, aquel que supieron construir con el esfuerzo cotidiano generaciones de indígenas, criollos e inmigrantes, transmitiendo sus saberes de manera práctica y oral, en búsqueda de soluciones para un hábitat que los cobijara.Usando tientos de cuero en las uniones; horcones, tablones y tejuelas de las maderas más diversas del monte nativo; o media caña de palmera o paja en los techos de los ranchos.A veces enramada unida con estiércol o barro, otras con grandes hojas secas o cañas en los cerramientos, casi siempre elevada, la vivienda separada del piso para evitar la humedad o directamente el agua, en humedales o zonas costeras de arroyos y ríos. De colores intensos en combinaciones insólitas para diferenciarlas del eterno verde del entorno; para las hamacas, disponen de largas galerías como espacio de transición del exterior al interior, en algunos casos con cambio de pendiente del techo, por ser un agregado posterior en las casas construidas por los colonos venidos de Europa que de esta forma lograban su acondicionamiento de aquellos fríos a estos climas. Con hornos de barro, los tatacuá ? del guarani: horno, cueva del fuego[1] ?, las casitas, corrales, graneros, secaderos, silos, escuelas y capillas de madera resisten el paso del tiempo, algunos en falsa escuadra, casi a punto del derrumbe pero firmes en ese delicado equilibrio, aún en su lugar, sirviendo de refugio, abrigo, defensa y resguardo a sus usuarios. En este sentido, ICOMOS en la Carta de Patrimonio Tradicional o Vernáculo plantea que Gobiernos y autoridades deben reconocer el derecho de todas las comunidades a mantener su modo de vida tradicional y a protegerlo a través de todos los medios posibles, tanto legales como administrativos y financieros y legarlo a las generaciones futuras.http:\/\/www.international.icomos.org\/charters\/vernacular_sp.htmEs así como a pesar de las malas condiciones de su resguardo, estos bienes resisten, como testigos de un tiempo de esfuerzos que ayudó a la conformación del espacio argentino actual, su territorio y su paisaje. Por ello merecen ser conservados a fin de recordarnos y mostrarles a las futuras generaciones, parte de nuestro pasado, de dónde venimos y proyectarnos desde ciertas certezas hacia el futuro?________________________________________[1] JOVER PERALTA, A. y OSUNA, T. (1984): Diccionario Guaraní-Español y Español-Guaraní, Asunción: Tupä.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241650,"idioma_id":4,"titulo":"Constituents of Flourensia blakeana (Asteraceae)","resumen":"Chemical study of the aerial parts of Flourensia blakeana Dillon allowed the isolation and identification of two novel compounds, 3, 5, 5´-trihydroxy-7, 3´-dimethoxyflavanone (1), and 2&#945;-angeloyloxycostic acid (2) together with several known compounds. The structures were elucidated using spectroscopic data from 1D, 2D NMR and HRDEIMS experiments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241663,"idioma_id":5,"titulo":"Entrevista a Trinh Minh-ha","resumen":"Ana Amado y Mónica Szurmuk entrevistaron a Trinh T. Minh-ha en de 2015 cuando visitó Buenos Aires por primera vez para la retrospectiva de su filmografía que se realizó en el contexto del Festival Internacional de Cine y Formación en Derechos Humanos de las personas migrantes. Nacida en Hanoi en 1952, Trinh T. Minh-ha creció durante la guerra de Vietnam y emigró a los Estados Unidos en 1970. Es profesora de Estudios de Género y de Retórica en la Universidad de California en Berkeley. Es además directora de cine, escritora y compositora. Su producción académica y artística es múltiple y a menudo combina diferentes géneros en obras líricas imposibles de clasificar. Su flimografía incluye Reassemblage (1982), Naked Spaces - Living is Round (1985), Surname Viet Given Name Nam (1989), Shoot for the Contents (1991), A Tale of Love (1995), The Fourth Dimension (2001), Night Passage (2004) y Forgetting Vietnam  (2015). Ha publicado además varios libros que son a la vez reflexiones teóricas, personales y artísticas, entre ellos  Woman, Native, Other. Writing Postcoloniality and Feminism (Indiana Universty Press 1989), Elsewhere, Within Here. Immigration, Refugeeism and The Boundary Event (Routledge 2010) y D-Passage. The Digital Way (Duke University Press, 2013).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241664,"idioma_id":5,"titulo":"1 de mayo en Tulchin: Extravío y Literatura","resumen":"En este texto parto de mi experiencia personal en la escritura de una biografía intelectual de Alberto Gerchunoff para describir ciertas particularidades del género biográfico y su relación con la escritura autobiográfica y con la crítica literaria. Propongo pensar en el extravío como figura de la biografía. La biografía es un género que propone, como la vida misma, múltiples caminos, que se pueden seguir o no. Es un género de la realidad pero también es un género de la corporalidad. Si todo trabajo intelectual nos atraviesa, la biografía se nos instala en el cuerpo y nos invita a releer nuestra propia vida. ¿A qué le damos importancia? ¿A qué no?  La biografía es la que escribe el biógrafo y hay tantas posibilidades biográficas como biógrafos. Si bien hay datos que coinciden el mundo textual que creamos para nuestro personaje refleja nuestras propias predilecciones. ¿Qué fuentes usar? ¿cómo dar cuenta de la subjetividad de la voz que cuenta la vida del\/de la otro\/a?  ¿a quién leer? ¿qué saber? ¿qué ignorar?","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241668,"idioma_id":5,"titulo":"Reseña de Vázquez, Hernán Gabriel. 2015. Conversaciones en torno al CLAEM. Entrevistas a compositores becarios del Centro Latinoamericano de Altos Estudios Musicales. Buenos Aires: Instituto Nacional de Musicología ?Carlos Vega?, 288 páginas.","resumen":"Reseña de Vázquez, Hernán Gabriel. 2015. Conversaciones en torno al CLAEM. Entrevistas a compositores becarios del Centro Latinoamericano de Altos Estudios Musicales. Buenos Aires: Instituto Nacional de Musicología ?Carlos Vega?, 288 páginas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241669,"idioma_id":5,"titulo":"Señales ofrecidas a través de los recursos de internet para reducir la incertidumbre de los consumidores de servicios de hospedaje","resumen":"El uso creciente de los social media asociado al ingente volumen de contenido generado por los usuarios ha transformado la comercialización del sector hotelero. Los usuarios acceden a información sobre establecimientos y prestaciones provenientes de diversos actores discurriendo en comunidades en línea, plataformas de información y sitios corporativos. Dado el hábito de los usuarios de obtener garantías sobre la seguridad en la contratación o confirmar la calidad de las prestaciones anunciadas antes de efectuar la adquisición del servicio, internet permite a las empresas del sector ofrecer señales para atraer su atención y diferenciar así una propuesta comercial entre la vasta oferta disponible. En el marco de las Teorías de Agencia y de Señales, el propósito del trabajo es analizar el aprovechamiento de los recursos de internet para influir en la decisión de compra de los consumidores a través de la presentación de señales de confianza y calidad en los hoteles de 3, 4, 5 estrellas y boutique de la ciudad de Mar del Plata [República Argentina] durante el año 2016. Se aborda una metodología cuantitativa de tipo descriptiva que muestra una adopción moderada de estas herramientas dificultando la publicación de señales para reducir la incertidumbre en los usuarios. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241670,"idioma_id":4,"titulo":"Phylogenetic and divergence time analysis of the Chelonoidis chilensis complex (Testudines: Testudinidae)","resumen":"We present a phylogenetic and divergence time analysis of the Chelonoidis chilensis complex (the southernmost tortoises of South America) within crown Testudinidae. We compiled a dataset of 1118 bp cytochrome b (cyt b) sequences derived from 111 individuals sampled across the known geographic range of the species, and performed a phylogenetic analysis employing Maximum Parsimony, Maximum Likelihood and Bayesian Inference methods. The resulting trees showed similar topologies and support values. The C. chilensis complex was always recovered as a monophyletic group composed by two major clades (i.e. haplogroups). The biogeographic distribution of one of these clades overlaps with the Dry Chaco eco?region, while the biogeographic distribution of the other overlaps with the Monte eco?region. In order to date the origin and diversification time of these two clades, we employed a previously published two-step molecular clock method. In the first step we dated the time of origin of C. chilensis as a clade within the Testudinidae family using new and previously published sequences, extinct testudinid taxa for age calibration and the Fossilized Birth-Death (FBD) model. In the second step we dated the divergence between the haplogroups of C. chilensis based on the time of origin estimated in the first step and a coalescent evolution model. Our results suggest that divergence between Dry Chaco and Monte tortoises may have occurred about 2.47 million of years ago. We interpret these results in the light of the environmental and geological changes that occurred during the late Pliocene to Middle Pleistocene of South America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241671,"idioma_id":5,"titulo":"Herramientas Útiles para la Evaluación de la Calidad de Ontologías Durante su Ciclo de Vida","resumen":"The Software Engineering (SE) community is using ontologies to solve different problems and their quality must be evaluated like any other SE artifact. Ontology evaluation methods generally quantify the quality of the final product. In this paper, based on the measures proposed in OntoQualitas, new guidelines are inferred to evaluate the quality of an ontology in different phases of its life cycle. Evaluating possible errors in these phases allows a better quality, achieved through feedback.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241672,"idioma_id":5,"titulo":"Productividad de rúcula (Eruca sativa Mill.) en diferentes sistemas productivos.","resumen":"El cultivo de rúcula en Argentina es relativamente nuevo, se produce en los cinturones hortícolas que rodean los principales centros urbanos de todo el país (Censo Nacional Agropecuario, 2002). En la actualidad, su empleo se ha incrementado para saborizar ensaladas, embutidos, pizzas, pastas, risottos y aperitivos (Morales y Janick, 2002; Hurrell et al, 2008). En los últimos años se ha observado una demanda creciente de esta hortaliza, sobre todo en las grandes ciudades como Buenos Aires, Córdoba y Rosario (Ferratto et al, 2010).El Cinturón Hortícola de Rosario es el más importante de la provincia de Santa Fe, no sólo por su producción sino también por la actividad comercial. La misma se realiza principalmente a través de dos mercados concentradores que abastecen a más de 2,5 millones de habitantes (Ferrattoet al, 2010). En esta región se realiza una gran diversidad de cultivos hortícolas, entre los que se destaca la rúcula, que en los últimos años ha cobrado gran importancia comercial. Se visualizó un incremento de 30 ha en el último censo realizado en 2012 (Grasso et al, 2013), en comparación al de 2008 (Ferratto et al, 2009); esto representa un aumento del 43 %.El objetivo del trabajo fue evaluar el efecto de los sistemas de producción, invernadero, media sombra, manta flotante y campo, en las pérdidas poscosecha de rúcula en distintas épocas de cultivo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241673,"idioma_id":5,"titulo":"'Un loco al que se le fue la mano' una análisis de la masacre de puente Pueyrredón","resumen":"Proponemos pensar estos acontecimientos a partir de una categoría nativa surgida en nuestras investigaciones sobre fuerzas de seguridad. Se trata de la categoría ?loco?, una forma de habitar la institución que apareció de manera constante en los discursos de los funcionarios. Precisamente, nos interesa dar cuenta de lo que el ex Comisario de la Policía de la Provincia de Buenos Aires, Alfredo Fanchiotti, en tanto ?loco,? podría significar como posición de sujeto en el campo policial.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241674,"idioma_id":5,"titulo":"La marca de la gorra","resumen":"Nuestras investigaciones revelan que quienes ingresan a la policía como Carlos buscan un trabajo, el mejor posible. Dada su formación y sus expectativas simbólicas, ser policía es una buena opción. Es un trabajo que, aunque tal vez se encuentre devaluado socialmente, inspira respeto, no como ascendiente moral pero sí el respeto derivado de la autoridad o el miedo. En la escuela de policía aprenden que deben desprenderse del (des)orden civil e internalizar un nuevo orden jerárquico y moral dentro del cual hay ciertas cuestiones que funcionan como capitales simbólicos. Por ejemplo, la vocación. Carlos aprende a tener vocación, a pensar su labor no como un simple trabajo sino como una misión, a leer en clave de vocación toda su historia previa: incluso los juegos infantiles más triviales, como el poliladron, pasan a ser entendidos como indicios de esa vocación temprana.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241675,"idioma_id":5,"titulo":"Investigamos_e: en búsqueda del re-encuentro entre el tiempo de la enseñanza y el tiempo del aprendizaje.","resumen":"El interés focalizado, la atención intermitente y laespacialidad itinerante son las nuevas realidades de losy las adolescentes que acceden a la Secundaria NuestraSeñora de Luján Buen Viaje de la Localidad de LomaHermosa, Partido de General San Martín (Pcia. de Bs As).Estos rasgos de las nuevas generaciones de estudiantesplantean el problema del desencuentro entre el tiempode la enseñanza y el tiempo del aprendizaje. A partir deese diagnóstico se diseñó en dicha escuela el proyectode investigación en Ciencias Sociales ?Investigamos_e?,cuyas metas principales consisten en que losadolescentes aprendan a investigar, investigando;que puedan experimentarse como productores deconocimiento en el marco de las Ciencias Sociales; y quevivencien nuevas formas de presencialidad en la EscuelaSecundaria por medio de la utilización de las TIC.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241676,"idioma_id":4,"titulo":"Photosynthesis and Growth of Temperate and Sub-Tropical Estuarine Phytoplankton in a Scenario of Nutrient Enrichment under Solar Ultraviolet Radiation Exposure","resumen":"We compared the responses of two estuarine phytoplankton communities, one from a temperate (Chubut River estuary (CH), Argentina) and one from a sub-tropical site (Babitonga Bay (BB), Brazil), in a scenario of nutrient enrichment under solar ultraviolet radiation (UVR) exposure. Seawater samples were exposed in microcosms to two nutrients, ambient vs. enriched, and two radiation conditions, with and without UVR, and exposed to solar radiation for 4&nbsp;days. We evaluated the short- (PSII photochemistry, during 90&nbsp;min light and 90&nbsp;min dark cycles, before and after the 4&nbsp;days of acclimation) and mid-term effects (growth and taxonomic changes) of the phytoplankton communities. Before acclimation, short-term UVR effects were dominant in CH, whereas in BB, nutrient effects prevailed. Such differences were related to the previous light history of the cells and to the ambient nutrient status. After acclimation, an overall improvement of the photosynthetic performance was observed at both sites, either by reducing the relative inhibition or by increasing the recovery of the effective photochemical quantum yield. Interactive effects of UVR and nutrients on growth at CH were antagonistic, while at BB, no differences were observed between the interactive and the sum of effects. Part of the differences in the mid-term observed responses can be attributed to taxonomic changes, with the CH community dominated by diatoms throughout the experiment, but with a shift from a diatom to a flagellate-dominated community in BB. Temperature differences between both sites might have favored higher growth rates and flagellates dominance in BB under the nutrient enriched conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241678,"idioma_id":4,"titulo":"Inelastic electron scattering in aggregates of transition metal atoms on metal surfaces","resumen":"Inelastic spin excitations, as observed with a scanning tunneling microscope for Co\/Co and Fe\/Fe dimers ona Cu2N\/Cu(100) surface, have been analyzed theoretically in this paper. In our approach, we use an extendedionic Hamiltonian for the magnetic atom that takes into account first, the role played by the first Hund rule inthe atomic states, and second, the cotunneling processes associated with the atomic excitations and the tunnelingconductance. This Hamiltonian is solved using the equation of motion method that yields the appropriate Green?sfunctions allowing us to calculate the differential conductance, the inelastic atomic excitations, and possibleKondo resonances. We also analyze an ideal dimer with spin ½ in each atom and discuss the differences andsimilarities this model has with the Co-Co case.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241679,"idioma_id":4,"titulo":"Electronic correlation effects on the neutralization of Ga+ scattered by a gold surface","resumen":"The monotonous increasing with temperature behavior of the neutralization of Ga+ scattered by a gold surface plus the nonmagnetic character of the ion induced to disregard the important electronic correlation effects. In this work, we show that contrary to this assumption, the electron-electron interaction in the Ga site is crucial for describing the experimental results. We extend the formalism previously used in the Sr+\/Au system to include more than one valence orbital in the projectile, which is the case of Ga+, where the neutralization occurs to a p-type shell. We consider the six possible orbital-spin neutral configurations in a correlated way within the Anderson model. The comparison with the results obtained from a noninteracting electron model allows one to infer how important the many-body effects in the charge exchange between Ga+ and the gold surface are. We also found that the proximity of the projectile one-electron energy levels to the substrate Fermi level determines the influence of electronic correlation effects on the neutral fraction and its temperature and velocity dependences.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241680,"idioma_id":4,"titulo":"Theoretical study of the charge transfer and electron emission in the scattering of He+ by an AlF3 surface","resumen":"Experimental results of electron emission from surfaces of aluminum fluoride impacted by keV noble gas ions (He+, Ne+, Ar+) show a high-energy structure that increases in intensity with ion energy in the case of He+ and Ar+ and is nearly independent on the impact energy for Ne+ ions. It is also observed that this high-energy secondary electron peak is less pronounced in the case of impact by Ar+. While ion-induced electron emission in metal surfaces is relatively well understood, in the case of wide band-gap insulators, such as metal fluorides, the nature of high-energy excitations is still an open question. In this work, we propose a mechanism of high-energy electron emission strongly linked to the ion neutralization process and the collision induced excitation of the electrons in the solid.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241682,"idioma_id":5,"titulo":"EL ESCENARIO DE  COMPLEJA OPORTUNIDAD, QUE PLANTEA LA ECUACIÓN: DEMANDA DE CUALIDADES POR PARTE DE LAS ORGANIZACIONES - LA OFERTA DE CAPACIDADES DE LOS JÓVENES PROFESIONALES EN CIENCIAS ECONÓMICAS DE LA CIUDAD DE ROSARIO.","resumen":"El artículo, intenta analizar cómo se articula la relación entre los jóvenes profesionales en Ciencias Económicas y las distintas organizaciones en  donde  se desempeñarán como profesionales, ante las nuevas realidades: complejidad, competitividad extrema, variaciones de variables de determinación, contexto con mayor grado de implicancia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241684,"idioma_id":5,"titulo":"?Factores de riesgo según la ocurrencia de accidentes laborales en el personal de enfermería del Centro Médico S.A de la ciudad de Corrientes durante el periodo del 1 enero al 31 diciembre del 2015","resumen":"Cabral, Claudia T.; y Col. Rev. Fac. Med. UNNE XXXVII: 2, 5-10, 2017Artículo Original?Factores de riesgo según la ocurrencia de accidentes laborales en elpersonal de enfermería del Centro Médico S.A de la ciudad deCorrientes durante el periodo del 1 enero al 31 diciembre del 2015?","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241686,"idioma_id":4,"titulo":"Growth, thermal desorption and low dose ion bombardment damage of C 60 films deposited on Cu(111)","resumen":"Auger Electron Spectroscopy (AES), Low Energy Electron Diffraction (LEED) and Reflection Electron Energy Loss Spectrometry (REELS) were used to characterize the growth and thermal stability of C60 films deposited on Cu(111). By means of LEED we found that while C60 grows in an ordered fashion up to the first monolayer (ML) at room temperature (RT), it turns amorphous beyond that point. On the other hand, when the substrate temperature is kept at 450K films up to two ML with crystalline structure are obtained. For substrate temperatures beyond 570K thick films (more than 1 ML) do not grow at all. By using AES, we found that a thick C60 film starts to desorb at a temperature around 470K but the first monolayer remains stable up to temperatures as high as 900K. A monolayer with a better crystalline order is obtained after desorption than that growth with the substrate at RT or higher temperatures. When the substrate is heated at 970K, the first monolayer is not fully removed but the C60 molecular structure is altered or molecules break up into smaller pieces. The ion induced damage on C60 on Cu(111) films was studied for typical ions, incoming energies and irradiation doses used in Low Energy Ion Scattering (LEIS) experiments. The D-value of C(KLL) Auger spectra and the &#61552;-plasmon of REELS, were monitored to characterize the damage caused to the film. We found that, at low doses (&#61566; 1014 ions\/cm2), damage is only detectable for massive ions like Ar, but not for H and He in the 2-8 keV range.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241687,"idioma_id":4,"titulo":"Intracontinental rift-related deposits: A review of key models","resumen":"Mineral systems associated with extensional fault systems in continental environments and not relatedto magmatic activity involve various deposit models that can be grouped into a single system whichwould plausibly explain the source and chemical composition of fluids, the formation depth, the sourceof heat and the structural history within a common geologic setting.Mineral deposits related to this tectonic setting are those described within the detachment-relatedmodel, including massive replacements, stockworks and veins of Cu and Fe oxides (with or withoutAu), polymetallic sulfide veins, barite and\/or fluorite veins and stratabound and vein Mn deposits. Thispaper reviews the abovementioned deposits as well as others related to this tectonic setting, such asSe-rich polymetallic deposits, Almadén type Hg deposits, U-Ni-Co-As-Ag polymetallic deposits with subordinated Bi-Cu-Pb-Zn (five element deposits), simple polymetallic Pb-Ag-Zn deposits, and the membersof the IOCG clan (including the Au-Ag detachment-related deposits) involved in the Cu-Fe (-Au) modeldeposits.All these mineral deposits are the result of fluid motion unrelated to magmatism in areas of thermalanomalies. These fluids collect certain elements producing a district mineralogical specialization withinhomogeneities in the distribution of mineralization types along the region affected by rifting. Fluidhomogenization temperatures and salinities range between 60 and 430 C, and 0 and 27 equivalentwt% NaCl, respectively. The O, S and D isotope composition is consistent with basinal poral fluids derivedfrom meteoric waters under different P-T conditions in an active faults environment. Pb isotopes suggestthat Pb derives from a mixture of rocks with a long period of residence in the upper crust and rocksdeformed along repeated orogenic cycles with a contribution of Pb from the lower crust and even themantle. Fluid flow along fault planes leads to different types of hydrothermal alterations depending onP-T conditions, particularly propylitization and low temperature potassium metasomatism.All such deposits can be found in two different geotectonic environments of metallogenic interestinvolving extensional faults associated with detachment zones in depth; i.e., 1) continental extensionin a back-arc environment and 2) extension with rift development and generation of oceanic crust in apassive continental margin. Although the economic importance of this group of deposits is mainly relatedto industrial minerals, non-magmatic IOCG deposits could significantly augment the economic potentialof this setting. The rift setting itself, without relation to detachments, is favorable for concentrating metals in stratabound deposits such as SEDEX ores. Additionally, the development of deposits directly relatedto magmatic activity contributes to the economic interest of this environment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241688,"idioma_id":4,"titulo":"Tourmaline orbicules in peraluminous monzogranites of Argentina: A study case of fluid-rock interaction between leucogranite and country-rock metasediments","resumen":"Tourmaline orbicules hosted in peraluminous granites aredocumented worldwide. Seven occurrences were identified in Argentina.Petrography, mineral chemistry, whole-rock geochemistry mass balance andmicrothermometric studies were performed in orbicules formed at the cupola of aperaluminous A-type leucogranite (Los Riojanos pluton), as well ascomplementary investigation was achieved in other orbicules of similargeological setting. Mass balance computations inzoned orbicules consistently confirmed immobility of Si both in core and halo, immobilityof K and little loss of Al during halo reactions. Elements gained and lost inthe schorl-rich core are Fe, Al, Mg, Ti, Ba, Sr, Y and Zr, and Na, K, Rb andNb, respectively; in the halo, K, Ba, Sr, Y, Zr and locally CaO, were gained,and Fe, Mg, Na, Al, Rb and Nb were lost. The schorl-rich core is enriched in LREErelative to the leucogranite host. A temperature-salinity plot fromfluid inclusion data delineates a magmatic-meteoric mixing trend of dilutingsalinity with descending temperature. Computed dDH20 values from Los Riojanos orbiculeschorl suggest magmatic and magmatic-meteoric mixed origins. In LosRiojanos, mass balance constraints suggest that Fe, Mg, Ba, Sr and metallictraces like Zn and V (±Pb) were most likely derived from country-rock schistsand gneisses through fluid-rock exchange reactions. A late magmatic-,volatile-rich- fluid exsolution scenario for the formation of orbicules isenvisaged. Schorl crystallization was likely delayed to the latest stages ofleucogranite consolidation, not only favored by the high diffusivity of B2O3preferentially partitioned into the exsolved aqueous-rich fluid, but also likelylimited to the low availability of Fe and Mg from the scarce granitic biotite,and to the high F- content of the melt. The spatial confination oforbicules to the contact zone granite-metasediments suggests that orbiculeswere not formed until exsolved fluids reached the boundary with the biotite-richcountry-rock. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241699,"idioma_id":4,"titulo":"The Trypomastigote Small Surface Antigen from Trypanosoma cruzi improves treatment evaluation and diagnosis in pediatric Chagas disease","resumen":"Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. Assessment of parasitological cure upon treatment with available drugs relies on achieving consistent negative results in conventional parasitological and serological tests, which may take years to assess. Here, we evaluated the use of a recombinant T. cruzi antigen termed TSSA as an early serological marker of drug efficacy in T. cruzi-infected children. A cohort of 78 pediatric patients born to T. cruzi-infected mothers was included in this study. Solely 39 of them were infected with T. cruzi, and were immediately treated with trypanocidal drugs. Serological responses against TSSA were evaluated in infected and non-infected populations during the follow-up period using an in-house ELISA test, and compared to conventional serological methods. Anti-TSSA antibody titers decreased significantly faster than anti-whole parasite antibodies detected by conventional serology in both T. cruzi-infected patients undergoing effective treatment and in those not infected. This differential kinetics allowed a significant reduction in the required follow-up periods to evaluate therapeutic responses or to rule out maternal-fetal transmission, respectively. Finally, we present the case of a congenitally-infected patient with atypical course, in which TSSA provided an early marker for T. cruzi infection. In conclusion, we showed that TSSA was efficacious both for rapid assessment of treatment efficiency and for early negative diagnosis in infants at risk of congenital T. cruzi infection. Based upon these findings we propose the inclusion of TSSA for refining the post-therapeutic cure criterion and other diagnostic needs in pediatric Chagas disease.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241700,"idioma_id":4,"titulo":"The Trypomastigote Small Surface Antigen (TSSA) regulates Trypanosoma cruzi infectivity and differentiation","resumen":"Background: TSSA (Trypomastigote Small Surface Antigen) is an antigenic, adhesion molecule displayed on the surface of Trypanosoma cruzi trypomastigotes. TSSA displays substantial sequence identity to members of the TcMUC gene family, which code for the trypomastigote mucins (tGPI-mucins). In addition, TSSA bears sequence polymorphisms among parasite strains; and two TSSA variants expressed as recombinant molecules (termed TSSA-CL and TSSA-Sy) were shown to exhibit contrasting features in their host cell binding and signaling properties. Methods\/Principle findings: Here we used a variety of approaches to get insights into TSSA structure\/function. We show that at variance with tGPI-mucins, which rely on their extensive O-glycoslylation to achieve their protective function, TSSA seems to be displayed on the trypomastigote coat as a hypo-glycosylated molecule. This has a functional correlate, as further deletion mapping experiments and cell binding assays indicated that exposition of at least two peptidic motifs is critical for the engagement of the ?adhesive? TSSA variant (TSSA-CL) with host cell surface receptor(s) prior to trypomastigote internalization. These motifs are not conserved in the ?non-adhesive? TSSA-Sy variant. We next developed transgenic lines over-expressing either TSSA variant in different parasite backgrounds. In strict accordance to recombinant protein binding data, trypomastigotes over-expressing TSSA-CL displayed improved adhesion and infectivity towards non-macrophagic cell lines as compared to those over-expressing TSSA-Sy or parental lines. These phenotypes could be specifically counteracted by exogenous addition of peptides spanning the TSSA-CL adhesion motifs. In addition, and irrespective of the TSSA variant, over-expression of this molecule leads to an enhanced trypomastigote-to-amastigote conversion, indicating a possible role of TSSA also in parasite differentiation. Conclusion\/Significance: In this study we provided novel evidence indicating that TSSA plays an important role not only on the infectivity and differentiation of T. cruzi trypomastigotes but also on the phenotypic variability displayed by parasite strains.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241701,"idioma_id":5,"titulo":"El abordaje kinesiológico como estrategia de inclusión social","resumen":"Si se apuesta por un proceso de atención que pretende ser integral e interdisciplinario, es necesario pensar la práctica clínica desde una perspectiva que implica el cuestionamiento y la transformación permanente del modo en que se piensa la discapacidad, porque de ese modo se favorece a su vez que la sociedad se vaya transformando en función del lugar que se le va dando en cada momento a esta problemática. En otras palabras, la clínica no podrá separarse de una ética y una política que favorezcan una transformación social en la cual la discapacidad no quede ya relegada al lugar que históricamente se le ha otorgado.Actualmente, de acuerdo a lo que se describe en la Convención sobre los Derechos de las Personas con Discapacidad (ONU, 2006) y a la ley argentina que la ratifica (N° 26.378), el posicionamiento clínico, ético y político, es radicalmente diferente. Se plantea a la discapacidad como una construcción social y no como un problema individual, por lo que se requiere de estrategias que posibiliten la inclusión social de las personas con discapacidad, entendida ésta como la necesaria transformación de la sociedad en función de las múltiples formas de existencia humana, la amplia diversidad humana. Esta estrategia de inclusión social se nutre a su vez de tácticas que proporcionan no sólo procesos de atención (en el caso de que éstos sean necesarios), sino también, principalmente, sistemas de apoyo para las personas puedan llevar su vida delante de manera autónoma.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241702,"idioma_id":4,"titulo":"Nonlinear dynamic numerical analysis of a RC frame subjected to seismic loading","resumen":"In the context of seismic engineering, reliable modeling methodologies are needed to represent the nonlinear dynamic behavior of structures under the effect of the seismic action. Only in this way is it possible to assess the safety margin against structural collapse. However, in the case of reinforced concrete (RC) structures, numerical modeling still presents difficulties due to complex nonlinear material behavior. The aim of this paper is to evaluate the capability of numerical modeling with solid finite elements to represent a strongly nonlinear dynamic response of reinforced concrete structures under the effect of the seismic action. A second objective is to obtain modeling guidelines for this dynamic behavior. A numerical study was performed in order to reproduce the nonlinear dynamic response of a RC frame tested by Elwood and Moehle (2003) on a shaking table at the University of California, Berkeley (USA). A material model that employs the shear failure surface proposed by Ottosen (1977) was selected to represent the non-linear behavior of concrete. This material model has several parameters that define their behavior, which includes the crack width at which tensile stress decreases to zero after a strain softening process. This parameter and the strain based erosion limit were subjected to calibration. During the calibration process, the degree of numerical-experimental similarity was established along with conclusions about the sensitivity of numerical response to variations of the calibrated parameters. Finally, it can be concluded that the numerical model reproduces the nonlinear response with sufficient accuracy. Moreover, the explicit time integration scheme shown to be appropriate for this type of problem with strong nonlinearities and degradation of the concrete.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241703,"idioma_id":4,"titulo":"Experimental and numerical study of the response of cylindrical steel tanks under seismic excitation","resumen":"To improve the structural seismic response ofliquid storage tanks, in the last 50 years, many researchershave developed different mathematical models, rangingfrom those based on discrete elements such as simplifiedtwo-mass models to those involving fluid?structureinteractions by complex formulations. To provide a broadoverview on the scope and accuracy of different numericallinear models, in this paper, a comparative study based onthe dynamic response assessment of cylindrical groundsupportedcontainers under seismic excitation is conducted.The dynamic response in terms of liquid sloshing height,base shear force and overturning moment is analysed bymeans of: (a) a simplified mechanical model in which thebehaviour of the liquid is represented by a discrete massspringsystem; (b) a complex model based on a Lagrangianfluid finite element approximation and (c) an experimentalscaled model whose measured response is considered asbenchmark. To obtain robust estimators of the structuralresponse, three different types of cylindrical tanks, includingbroad and slender tanks, subjected to real ground accelerationtime-histories are studied. The results indicate thatthe finite element model gives good approximation for allresponse parameters and the simplified mechanical modelunderestimate the sloshing height and overestimate baseshear force and overturning moment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241704,"idioma_id":4,"titulo":"Testing and performance of a new friction damper for seismic vibration control","resumen":"In the last two decades, great efforts were carried out to reduce the seismic demand on structures through the concept of energy dissipation instead of increasing the stiffness and strength. Several devices based on different energy dissipation principles have been developed and implemented worldwide, however, most of the dissipation devices are usually installed using diagonal braces, which entail certain drawbacks on apertures for circulation, lighting or ventilation and architectural or functional requirements often preclude this type of installations. In this work, a conceptual development of a novel energy dissipation device, called Multiple Friction Damper (MFD), is proposed and examined. To verify its characteristics and performance, the MFD was implemented on a single storey steel frame experimental model and tested under different conditions of normal force and real time acceleration records. Experimental results demonstrated that the new MFD constitutes an effective and reliable alternative to control the structural response in terms of displacement and acceleration. A mathematical formulation based on the Wen´s model reflecting the nonlinear behaviour of the device is also presented.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241705,"idioma_id":4,"titulo":"Structural analysis of the CAREM-25 nuclear power plant subjected to the design basis accident and seismic loads","resumen":"In this paper, a numerical study about the structural response of the Argentine nuclear power plant CAREM-25 subjected to the design basis accident (DBA) and seismic loads is presented. Taking into account the hardware capabilities available, a full 3D finite element model was adopted. A significant part of the building was modeled using more than 2 M solid elements. In order to take into account the foundation flexibility, linear springs were used. The springs and the model were calibrated against a greater model used to study the soil-structure interaction. The structure was subjected to the DBA and seismic loads as combinations defined by ASME international code. First, a transient thermal analysis was performed with the conditions defined by DBA and evaluating the time history of the temperature of the model, each 1 h until 36 h. The final results of this stage were considered as initial conditions of a static structural analysis including the pressure defined by DBA. Finally, an equivalent static analysis was performed to analyze the seismic response considering the design basis spectra for the site. The different loads were combined and the abnormal\/extreme environmental combination was the most unfavorable for the structure, defining the design.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241706,"idioma_id":4,"titulo":"Analytical, numerical and experimental studies on the Semi-Active Friction Tendon","resumen":"For controlling vibrations, a Semi-Active Friction Tendon (SAFT), which consists of a semi-active friction damper and anauxiliary spring that are linked to the structure by a cable, is studied experimentally, numerically and analytically. Two semiactivecontrol laws are implemented, one is based on velocity feedback (denoted as SQDCL) and the other is based on forcefeedback (denoted as SPCL); the passive control case is also studied for comparison. Based on the structural displacementreduction and the hysteretic behavior assessment, it is clearly demonstrated that (for SAFTs with a given pre-tension force): (1)the effectiveness of the optimized passive-control case can always be improved by using semi-active control with any of the twocontrol laws; and (2) the SPCL is more effective for large displacements, while the SQDCL is more advantageous for very smalldisplacements. Moreover, closed-form expressions for the dissipated energy are presented for the three cases under consideration,which can be used in preliminary design of SAFTs to decide between passive and semi-active control and to choose the moresuitable control law.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241707,"idioma_id":4,"titulo":"Control of relative vibration between flexible appendages using passive and semi-active isolation","resumen":"Relative vibration between two flexible subsystems can be detrimental to the performance of many engineering applications, such as optics-based instruments, machine tools, or adjacent industrial structures sharing piping. For the purpose of controlling this particular vibration, this paper presents two control approaches based on the passive and semi-active isolation at each subsystem: the indirect control method, consisting in the reduction of the individual vibration of each subsystem, and the direct control method, which aims to reduce the relative vibration between both subsystems. Necessary conditions for the feasibility of the direct control method are found, thereby reducing the universe of possible design configurations. From the traditional ground-hook and sky-hook control laws, which simulate, respectively, a damper between the body to be controlled and the support or the reference framework, it is generalized a control law called body-hook-body, which simulates a damper between both bodies to be controlled. Taking into account the performance and cost\/complexity of the whole system, different alternatives for each vibration control method are numerically and experimentally studied. From the results, it is inferred that the proposed direct control method, using body-hook-body, is as effective as the traditional indirect control method, using ground-hook or sky-hook, but with lower cost and complexity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241712,"idioma_id":4,"titulo":"Optical and electrical properties of nanostructured metallic electrical contacts","resumen":"We study the optical and electrical properties of silver films with a graded thickness obtained through metallic evaporation in vacuum on a tilted substrate to evaluate their use as semitransparent electrical contacts. We measure their ellipsometric coefficients, optical transmissions and electrical conductivity for different widths, and we employ an efficient recursive method to calculate their macroscopic dielectric function, their optical properties and their microscopic electric fields. The topology of very thin films corresponds to disconnected islands, while very wide films are simply connected. For intermediate widths the film becomes emicontinuous, multiply connected, and its microscopic electric field develops hotspots at optical resonances which appear near the percolation threshold of the conducting phase, yielding large ohmic losses that increase the absorptance above that of a corresponding homogeneous film. Optimizing the thickness of the film to maximize its transmittance above the percolation threshold of the conductive phase we obtained a film with transmittance T = 0.41 and a sheet resistance Rs 2.7 max &#8776; &#937;. We also analyze the observed emission frequency shift of porous silicon electroluminescent devices when Ag films are used as solid electrical contacts in replacement of electrolytic ones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241713,"idioma_id":5,"titulo":"El concepto de inmanencia práctica en Deleuze","resumen":"En este trabajo presento el concepto de ?inmanencia práctica? como la clave de la ética que Deleuze elabora a partir de Spinoza y de Nietzsche. Esta noción involucra tres tesis que ponen de manifiesto la reivindicación incondicional de la inmanencia y la crítica de toda instancia trascendente: la valorización del cuerpo en detrimento de la conciencia; la apelación a lo bueno y lo malo, en lugar del Bien y el Mal, como criterios de valoración de los modos de existencia; la apología de la alegría y de la inocencia del devenir. La hipótesis que desarrollo sostiene que esta ética naturalista y pluralista se apoya en criterios de valoración ligados a la vida, postulada como el punto fundamental de apreciación, y propone la creación de nuevas maneras de ser como medio de enfrentar el sistema del juicio moral sobre el cual descansa el nihilismo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241714,"idioma_id":4,"titulo":"Diversity of human herpesvirus 8 genotypes in patients with AIDS and non-AIDS associated Kaposi's sarcoma, Castleman's disease and primary effusion lymphoma in Argentina","resumen":"HHV-8 genotypes are distributed heterogeneously worldwide. The variable K1 gene and the conserved ORF26E region serve to genotype. The aim of the study was to characterize HHV-8 isolates from patients with AIDS, classical, and iatrogenic KS, primary effusion lymphoma and Castleman´s disease and one organ donor from Argentina by analysis of ORFK1 and ORF26E regions. DNA was extracted from fresh or paraffin embedded biopsies, blood, and saliva samples and submitted to HHV-8 PCR. Phylogenetic analyses of ORFK1 showed that subtypes C (C1, C2, and C3), B1 and A (A1, A2, and A3) were present in 70.8%, 16.7%, and 12.5% of cases, respectively. Analyses of ORF26E fragment revealed that most strains (45.8%) were subtype A\/C while the remaining fall into K, J, B2, R, and D subtypes. Linkage between ORFK1-ORF26E subtypes corresponded to reported relationships, except for one strain that clustered with B1 (K1 African) and D (ORF26E Asian-Pacific) subtypes. This research reveals predominance of subtype C, a broad spectrum of HHV-8 genotypes and reports the first isolation of the African B genotype in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241715,"idioma_id":5,"titulo":"La energía y su conservación como eje estructurante para la comprensión de fenómenos electromagnéticos","resumen":"La energía y su principio de conservación es un concepto articulador en la Física, y está presente en la enseñanza de todas sus áreas, pero mientras en algunas, como mecánica o termodinámica, se presenta de modo integrado, en electromagnetismo su presentación es fragmentada e incompleta. En este trabajo proponemos una secuencia didáctica para el nivel universitario básico, que rescata el teorema de Poynting como expresión del principio de conservación de la energía en el electromagnetismo para dar cuenta de los procesos energéticos que involucran tanto circuitos eléctricos como interacciones entre campos eléctricos y magnéticos. Esta secuencia viene siendo implementada desde hace varios años en un curso básico de electromagnetismo para carreras de ingeniería y responde al reclamo de numerosos autores que señalan la ausencia de la discusión de la interacción entre los campos electromagnéticos en circuitos eléctricos y de los procesos de transferencia de energía entre fuente y dispositivos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241721,"idioma_id":4,"titulo":"Dairy propionibacteria prevent the proliferative effect of plant lectins on SW480&nbsp;cells and protect the metabolic activity of the intestinal microbiota in&nbsp;vitro","resumen":"Plant lectins are specific carbohydrate-binding proteins that are widespread in legumes such as beans and pulses, seeds, cereals, and many plants used as farm feeds. They are highly resistant to cooking and digestion, reaching the intestinal lumen and\/or blood circulation with biological activity. Since many legume lectins trigger harmful local and systemic reactions after their binding to the mucosal surface, these molecules are generally considered anti-nutritive and\/or toxic substances. In the gut, specific cell receptors and bacteria may interact with these dietary components, leading to changes in intestinal physiology. It has been proposed that probiotic microorganisms with suitable surface glycosidic moieties could bind to dietary lectins, favoring their elimination from the intestinal lumen or inhibiting their interaction with epithelial cells. In this work, we assessed in vitro the effects of two representative plant lectins, concanavalin A (Con A) and jacalin (AIL) on the proliferation of SW480 colonic adenocarcinoma cells and metabolic activity of colonic microbiota in the absence or presence of Propionibacterium acidipropionici CRL 1198. Both lectins induced proliferation of colonic cells in a dose-dependent manner, whereas ConA inhibited fermentative activities of colonic microbiota. Pre-incubation of propionibacteria with lectins prevented these effects, which could be ascribed to the binding of lectins by bacterial cells since P. acidipropionici CRL 1198 was unable to metabolize these proteins, and its adhesion to colonic cells was reduced after reaction with Con A or AIL. The results suggest that consumption of propionibacteria at the same time as lectins could reduce the incidence of lectin-induced alterations in the gut and may be a tool to protect intestinal physiology.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241722,"idioma_id":5,"titulo":"ética y conocimiento","resumen":"Este trabajo sostiene que las cuestiones metodologías y\/o epistemológicas no pueden separarse de las ético-valorativas en la producción de conocimiento. En este sentido propone que la producción de conocimiento debe estar orientada por una concepción ética indisociable de una teoría social crítica y  por  un sentido de la responsabilidad que tenga en cuenta de qué manera nuestras acciones pueden ser recibidas por el mundo social ya constituido y  cuáles pueden ser las consecuencias que de ellas se derivan.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241723,"idioma_id":5,"titulo":"Condena subsidiaria en materia de alimentos","resumen":"Introducción. La Sala M de la Cámara Nacional de Apelaciones en lo Civil, integrada por las doctoras Elisa M. Díaz De Vivar, Mabel De Los Santos y María Isabel Benavente juzgó en recurso de apelación interpuesto contra la sentencia de la primera instancia que decidió fijar cuota de alimentos provisionales de cinco mil pesos a favor de una persona menor, estableciendo a cargo de su padre la cantidad de pesos tres mil y de su abuela dos mil. La decisión fue apelada por esta última.Mediante concreta y fundamentada consideración el tribunal de la alzada resolvió revocar lo resuelto con relación a los alimentos provisionales de dos mil pesos cuyo pago se impuso a la abuela de la menor de autos, quedando a cargo del padre la cuota de cinco mil pesos fijada a favor de la menor.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241725,"idioma_id":5,"titulo":"Reparación de daños por incumplimiento de deberes matrimoniales","resumen":"Síntesis del casoEn vigencia del Código Civil, un cónyuge promovió juicio de divorcio vincular contra el otro, por la causal de injurias graves. En ello manifestó que su esposo la hizo blanco de todo tipo de calumnias e injurias, imputándole la calidad de infiel y haciendo comentarios agresivos tanto en público como ante el grupo familiar. En su presentación encuadró la conducta del demandado en lo previsto por el derogado art. 202 inc. 4 del Cód. Civil.Su marido respondió la petición solicitando su rechazo y articulando reconvención, exponiendo que su esposa era infiel. Solicitó que se declare el divorcio por culpa de la actora por las causales de adulterio, tentativa contra su vida, injurias graves y abandono voluntario y malicioso de parte de su esposa, en los términos de los derogados arts. 214 inc. 1° y 202, incs. 1°, 2°, 4° y 5° del Código Civil, y reclamó la reparación del daño moral.La actora solicitó se rechace de la reconvención y que se haga lugar a su demanda.En su oportunidad procesal la sentencia de la primera instancia desconoció las causales de divorcio denunciadas en la demanda y la reconvención, decretó el divorcio vincular por la causal contemplada por el art. 214 inc. 2° del Código Civil sin culpa de las partes, decretando la disolución de la sociedad conyugal con efecto retroactivo a la fecha de notificación de la demanda y rechazando el reclamo por daño moral del reconviniente.Apelaron el demandado reconviniente, quien sostuvo que la jueza falló extrapetita en tanto criticó el régimen del anterior Código Civil sin hacer mérito de los respectivos intentos de acreditar las causales de divorcio; valoró erróneamente la prueba respecto de la atribución de la culpabilidad y rechazó sin fundamentos el reclamo del daño moral.De su lado la actora se agravió al decir que la juez no consideró acreditadas las injurias que atribuyó al demandado y se autolimitó amparándose en un criterio restrictivo para analizar la prueba de las causales y en la pronta derogación del sistema de culpas en ese entonces imperante.Coincidieron ambas en sus quejas en cuanto la sentenciante aludió a las reformas legislativas que en ese momento aún no estaban vigentes.El expediente ingresó a la alzada en vigencia del Código Civil y Comercial de la Nación que derogó las causales objetivas y subjetivas del divorcio, aspecto que constituyó el contenido de la totalidad de los agravios de ambos apelantes.La Cámara de Apelaciones en lo Civil, Comercial, Laboral y de Minería de la Segunda Circunscripción Judicial, con asiento en General Pico, provincia de La Pampa, integrada por los jueces Horacio A. Constantino, Rodolfo F. Rodríguez y Roberto M. Ibañez, resolvió decretar el divorcio en forma incausada en los términos del art. 437 del Código Civil y Comercial de la Nación y condenaron a la actora reconvenida al pago de un monto dinerario en concepto de daño moral.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241726,"idioma_id":4,"titulo":"Molecular identification and technological characterization of lactic acid bacteria isolated from fermented kidney beans flours ( Phaseolus vulgaris L. and P. coccineus ) in northwestern Argentina","resumen":"Legumes are an important protein source in developing countries and their flours represent an attractive alternative for the manufacture of gluten free products. In the present study, 4 kidney bean varieties (Alubia, Pallar, Black and Red beans) commonly cultivated in northwestern Argentina, were milled and spontaneously fermented in order to isolate and select autochthonous lactic acid bacteria (LAB) with relevant technological and functional properties for usage as starter cultures. Twelve doughs were fermented with daily back-slopping at 37 &deg;C for 6 days and evolution of total mesophiles, lactic acid bacteria, and yeasts and molds populations were followed by plate counting. A combination of phenotypic and genotypic methods including (GTG)5-based PCR fingerprinting and 16S rRNA gene sequencing were used to differentiate and identify the isolated LAB to species level. LAB counts ranged from around 0.89 &plusmn; 0.81 to 8.74 &plusmn; 0.03 log cfu\/g with a pH decline from 6.4 to 3.9 throughout fermentation. Four genera and nine species of LAB: Enterococcus durans, E. faecium, E. mundtii, E. casseliflavus; Lactobacillus rhamnosus, Lactococcus garvieae, Weissella cibaria and W. paramesenteroides were found on kidney beans. Twenty five LAB strains were assessed for their abilities to grow on kidney bean extracts, acidifying capacities (pH and acidification rates), amylolytic, proteolytic, tannase and gallate decarboxylase activities as well as pathogens inhibition by antimicrobials. Based on these properties E. durans CRL 2178 and W. paramesenteroides CRL 2182 were inoculated singly and combined in Alubia kidney bean flour and fermented for 24 h at 37 &deg;C. LAB strains were beneficial for removing trypsin inhibitors and tannins from sourdoughs and for improving amino acids and phenolics contents, increasing the antioxidant activities of kidney bean matrices. Selected strains have potential as starter cultures for obtaining fermented bean products with high nutritional and functional quality.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241727,"idioma_id":5,"titulo":"Grasas trans en alimentos","resumen":"Si bien los alimentos contienen una mezcla de ácidos grasos saturados y no saturados, en general, los provenientes de animales terrestres (grasa de carne, leche, queso, manteca, crema) contienen más ácidos grasos saturados que los de origen vegetal, mientras que los vegetales (aceitunas, frutos secos, girasol, soja) y el pescado tienen más ácidos grasos insaturados. A nivel industrial, los aceites que tienen alto contenido de ácidos grasos insaturados se oxidan con más facilidad, creando compuestos que tienen olores o sabores rancios y desagradables. Para disminuir el número de enlaces dobles y retardar o eliminar la posibilidad de oxidación, se somete al aceite a un proceso químico, llamado hidrogenación, por medio del cual se le añade más hidrógeno. Paralelamente, ocurren reacciones secundarias como la isomerización de los dobles enlaces cis a la configuración trans que es más estable.Los conocimientos sobre el efecto biológico de los ácidos grasos trans en el organismo, producidos durante la última década, indican que los productos obtenidos por hidrogenación tienen efectos nocivos y que el consumo excesivo de lípidos ricos en ácidos grasos saturados y los trans pueden provocar enfermedades y aumentar el riesgo de mortalidad. En todo el mundo se han probado diversas estrategias para reemplazar los procesos de hidrogenación tradicionales por otros que permitan reducir el contenido de los ácidos grasos trans de los productos: modificación de la composición de las semillas, fraccionamiento, interesterificación. Finalmente, debido a que en las etiquetas de los alimentos debe figurar la cantidad de ácidos grasos trans, como consumidor la manera de limitar su consumo es leyendo las etiquetas del envase.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241728,"idioma_id":5,"titulo":"?Vicisitudes de la igualdad?","resumen":"Este artículo procura examinar las condiciones de asimetría en el ejercicio de poder desde una perspectiva que relaciona el desarrollo científico-tecnológico y la concepción de vida de la biotecnología con las dinámicas de la gubernamentalidad neoliberal. Para ello analiza críticamente las nociones de ciudadanía e igualdad contenidas en la teoría socio-política enmarcadas en el liberalismo  y su significado y alcance para el efectivo cumplimiento de los Derechos Humanos.Desde este punto de vista propone considerar las condiciones de posibilidad para el desarrollo de un enfoque de la Bioética desde el cual ésta se reconoce inscripta en un contexto social y político particular y como parte interesada en la interpretación y transformación de la vida socio-política.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241732,"idioma_id":4,"titulo":"Resolving the circumstellar environment of the Galactic B[e] supergiant star MWC 137 from large to small scales.","resumen":"The Galactic object MWC 137 was suggested to belong to the group of B[e] supergiants. However, with its large-scale optical bipolar ring nebula and the high velocity jet and knots, it is a rather atypical representative of this class. We performed multi-wavelength observations spreading from the optical to the radio regime. Based on optical imaging and long-slit spectroscopic data we found that the northern parts of the large-scale nebula are predominantly blue-shifted, while the southern regions appear mostly red-shifted. We developed a geometrical model consisting of two double-cones. While various observational features can be approximated with such a scenario, the observed velocity pattern is more complex. Using near-infrared integral-field unit spectroscopy we studied the hot molecular gas in the close vicinity of the star. The emission from the hot CO gas arises in a small-scale disk revolving around the star on Keplerian orbits. While the disk itself cannot be spatially resolved, its emission is reflected by dust arranged in arc-like structures and clumps surrounding MWC 137 on small scales. In the radio regime we mapped the cold molecular gas in the outskirts of the optical nebula. We found that large amounts of cool molecular gas and warm dust embrace the optical nebula in the east, south and west. No cold gas or dust were detected in the north and north-western regions. Despite the new insights on the nebula kinematics gained from our studies, the real formation scenario of the large-scale nebula remains an open issue.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241733,"idioma_id":4,"titulo":"Mok's characteristic varieties and the normal holonomy group","resumen":"In this paper we complete the study of the normal holonomy groups of complex submanifolds (non nec. complete) of Cn or CPn. We show that irreducible but non-transitive normal holonomies are exactly the Hermitian s-representations of [4, Table 1] (see Corollary 1.1). For each one of them we construct a non necessarily complete complex submanifold whose normal holonomy is the prescribed s-representation.We also show that if the submanifold has irreducible non-transitive normal holonomy then it is an open subset of the smooth part of one of the characteristic varieties studied by N. Mok in his work about rigidity of locally symmetric spaces.Finally, we prove that if the action of the normal holonomy group of a projective submanifold is reducible then the submanifold is an open subset of the smooth part of a so called join, i.e. the union of the lines joining two projective submanifolds.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241734,"idioma_id":5,"titulo":"Estudio dialógico sobre el desarrollo de la enseñanza.","resumen":"La construcción del yo (self) implica una selección e internalización de voces internamente convincentes. Así, investigar el desarrollo de procesos de enseñanza y aprendizaje desde una perspectiva dialógica significa atender a la polifonía discursiva inherente a la identidad docente. Entrevistamos dos profesores de una misma carrera universitaria con el objetivo de explorar qué voces\/posiciones e innovaciones personales despliegan cuando hablan de la enseñanza y el aprendizaje en la universidad. Los resultados muestran que ambos profesores se asociaron a un conjunto diferente de voces e innovaciones: movimientos desde posiciones con foco en voces de otros hacia posiciones con mayor grado de integración entre voces del yo y de otros, así como movimientos desde innovaciones centradas acciones observables como protestas y acciones propiamente dichas hacia innovaciones centradas en acciones mentales como reflexiones y reconceptualización. Ello implicó poner en evidencia formas de interiorización de la agencia en la enseñanza y el aprendizaje: (a) de una agencia externa, observable a una agencia interna, mental; (b) de una gestión externa del aprendizaje, realizada por otros, a una gestión interna, en la que el propio aprendiz debe asumir la gestión de sus propios procesos de aprendizaje. Implicancias educativas son discutidas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241736,"idioma_id":5,"titulo":"Importancia de la farmacovigilancia en medicina herbaria","resumen":"RESUMEN Introducción: el uso de hierbas medicinales para la prevención y el tratamiento de diversas enfermedades es una práctica ancestral. A pesar del papel beneficioso y tradicional de las mismas en diferentes comunidades, hay que considerar que también pueden provocar reacciones adversas y toxicidad. Objetivo: analizar las notificaciones sobre reacciones adversas de productos medicinales a base de hierbas durante el período 2010-2016 en la provincia del Chaco, Argentina. Métodos: estudio retrospectivo, transversal y descriptivo. Se evaluaron las notificaciones de reacciones adversas a partir de los datos obtenidos de la ficha de Comunicación de Eventos Adversos por uso de Medicamentos Fitoterápicos, Productos Vegetales y\/o Preparados de Drogas Vegetales, recibidas de farmacias y centros de salud de la provincia del Chaco, Argentina, como efectores periféricos del Sistema Nacional de Farmacovigilancia de la Administración Nacional de Medicamentos, Alimentos y Tecnología Médica (ANMAT). Resultados: se recibieron un total de 129 notificaciones, se observó un predominio de reacciones adversas por el uso de productos medicinales a base de hierbas en el sexo femenino y un considerable porcentaje de las mismas que incluyó a lactantes y niños, siendo el paico ( Chenopodium ambrosioides L.) el más reportado en este grupo etario y sen (Cassia angustifolia Vahl.) en adultos. La mayoría de las reacciones adversas notificadas correspondieron a trastornos del sistema gastrointestinal. En cuanto a la intensidad e imputabilidad predominaron las leves y probables respectivamente. Conclusiones: es primordial la vigilancia continua de las medicinas a base de hierbas para promover su uso seguro sobre todo en poblaciones vulnerables.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241739,"idioma_id":5,"titulo":"La interrelación de los recursos, clave de la competitividad interna","resumen":"Asistiendo en los últimos diez años a cambios estructurales en las variables que determinan el estado de desarrollo y crecimiento d elos distintos sectores industriales tanto en Argentina como en Latinoamérica, los que tienen que ver con una percepció distinta del negocio, los que afectaron los índices de liquidez de las empresas, su posibilidad de crecimiento, su capacidad de endeudamiento, su posibilidad de reconversión, el proyecto se compromete con el estudio exploratorio y concluyente de las variables que sostienen la competitividad interna y que más luego respaldarán su competitividad externa.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241742,"idioma_id":5,"titulo":"Aportes a la colección de hongos liquenizados del herbario del Instituto de Botánica Carlos Spegazzini (LPS)","resumen":"El Instituto de Botánica Carlos Spegazzini (IBCS) (UNLP, La Plata) contiene un herbario de hongos (LPS) de aproximadamente 40000 ejemplares, con 4200 especies tipo. El objetivo de este trabajo fue examinar los ejemplares de hongos liquenizados depositados en el IBCS, actualizar su taxonomía y denominación, revisar las especies con determinación dudosa, identificar aquellos no determinados, e incorporarlos en el Herbario LPS. Se estudiaron 192 ejemplares de 11 provincias de Argentina y de Brasil, Uruguay y Francia y de se determinaron en base a su exo-morfología, cortes histológicos y reacciones histoquímicas. También se realizaron Cromatografías en Capa Delgada (TLC) paraestudiar los metabolitos presentes. Se estableció la distribución geográfica en Argentina de las especies identificadas. Se corrigió el 91,66% de los materiales examinados (176 ejemplares), contabilizándose un total de 91 especies, 50 géneros y 21 familias, siendo las mejor representadas Parmeliaceae (16 géneros; 31 especies), Graphidaceae (4; 5) y Physciaceae (3; 9). Se actualizó la nominación de 56 ejemplares pertenecientes a 32 especies. Se modificó la identidad de 120 ejemplares, a nivel de especie (87), género (33) y familia (1). Se amplía la distribución en Argentina de 9 especies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241744,"idioma_id":5,"titulo":"Figuras de la muerte en la Fenomenología del espíritu","resumen":"This paper proposes a transversal lecture of the Phenomenology of Mind from Hegel by following in the text the idea of death. To show the different figures of the death in the book, the author uses three lecture`s key: a) the death as natural end of the life, b) the fear of the death as regulative idea by the constitution the society, c) overcoming death through one kind of rational way of survival.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241745,"idioma_id":5,"titulo":"De victimas a victimarios. Sobre la racionalidad mediática-penal","resumen":"En el presente trabajo nos proponemos, como objetivo general, indagar sobre las construcciones mediáticas en torno a la figura del 'individuo peligroso' en el discurso de la prensa gráfica local, tomando como caso de análisis el Diario La Capital de Rosario. Para ello, procuraremos describir un procedimiento discursivo singular en el relato mediático a raíz de los resultados de nuestro trabajo de campo: la víctima de un delito, en caso de tener antecedentes penales, será configurado como victimario. Operación discursiva que cristaliza una de las tantas manifestaciones de una racionalidad mediática-penal neo-liberal donde por una parte, se condena justificando la muerte de la víctima por pertenecer a un sector social que no merece vivir y por otro, construye la figura de una víctima que pronto será victimario de si-mismo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241747,"idioma_id":5,"titulo":"Canon literario y canon escolar: algunas notas sobre el canon y lo político","resumen":"El trabajo aborda los conceptos de canon literario y canon escolar poniendo el acento en su dimensión política. Desde este punto de partida se explican algunos presupuestos que subyacen a la enseñanza de la literatura y a las elecciones canónicas","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241748,"idioma_id":5,"titulo":"Desarrollo de contenidos para el aprendizaje m-learning","resumen":"Los smartphones se han convertido en accesorios vitales y han cambiado la manera de vivir, de informar y de comunicarse, aunque no siempre se los utiliza de manera eficaz para el aprendizaje de contenidos científicos e ingenieriles. La posibilidad de acceder a la información en cualquier lugar o cualquier momento desde un dispositivo móvil, la interacción con pares o familiares, como así también el poder generar oportunidades estructuradas de aprendizaje desde una variedad de fuentes, son también realidades. Los autores que presentan este artículo conforman un equipo de investigación educativa abocados al aprendizaje y enseñanza de la ciencia y la ingeniería desde hace más de diez años; como resultado de esos estudios se advirtió la necesidad de poner en práctica algunas metodologías utilizando los dispositivos móviles. El objetivo es lograr aprendizajes significativos y generar algunas competencias en estudiantes universitarios de primer año y del último año del preuniversitario, contribuyendo al incentivo de vocaciones relacionadas a la ingeniería.Como resultado del desarrollo se obtuvieron paquetes de materiales didácticos conformados por guías, videos, clases grabadas y bibliografías conectadas a través de códigos QR, y una App especialmente diseñada a las que se accede desde los smartphones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241749,"idioma_id":4,"titulo":"On the mechanism of Candida tropicalis biofilm reduction by the combined action of naturally-occurring anthraquinones and blue light","resumen":"The photoprocesses involved in the photo-induced Candida tropicalis biofilm reduction bytwo natural anthraquinones (AQs), rubiadin (1) and rubiadin-1-methyl ether (2), were examined.Production of singlet oxygen (1O2) and of superoxide radical anion (O2·&#8722;) was studied.Although it was not possible to detect the triplet state absorption of any AQs in biofilms,observation of 1O2 phosphorescence incubated with deuterated Phosphate Buffer Solution,indicated that this species is actually formed in biofilms. 2 was accumulated in the biofilm toa greater extent than 1 and produced measurable amounts of O2·&#8722; after 3h incubation in biofilms.The effect of reactive oxygen species scavengers on the photo-induced biofilm reductionshowed that Tiron (a specific O2·&#8722; scavenger) is most effective than sodium azide (aspecific 1O2 quencher). This suggests that O2·&#8722; formed by electron transfer quenching ofthe AQs excited states, is the main photosensitizing mechanism involved in the photoinducedantibiofilm activity, whereas 1O2 participation seems of lesser importance.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241780,"idioma_id":4,"titulo":"Responses to silver nanoparticles and silver nitrate in a battery of biomarkers measured in coelomocytes and in target tissues of Eisenia fetida earthworms","resumen":"The current use and development of applications with silver nanoparticles (Ag NPs) could lead to potential inputs of these NPs to soils. Consequently, it is crucial to understand the ecotoxicological risks posed by Ag NPs in the terrestrial compartment. In the present investigation, the effects produced by PVP-PEI coated Ag NPs were assessed in Eisenia fetida earthworms in comparison with the soluble form (AgNO3). Earthworms were exposed for 1, 3 and 14 days to a range of sublethal concentrations of Ag (0, 0.05 and 50 mg\/kg) and at each exposure time, apart from mortality and weight loss of individuals, metallothionein (MT) protein concentration and catalase (CAT) activity were quantified in earthworm tissues. In addition, cellular and molecular level endpoints (cell viability, absolute and relative trophic indices and transcription levels of catalase-cat- and metallothionein-mt-) were measured in coelomocytes extruded from exposed earthworms. Despite the lack of effects in traditional endpoints (mortality and weight loss), Ag NPs and AgNO3 posed changes at lower levels of biological complexity (biochemical, cellular and molecular levels). Both Ag forms induced similar changes in the metal detoxification mechanism (MT, mt) and in the antioxidant response system (CAT, cat) of E. fetida. In contrast, Ag form dependant cytotoxicity and subpopulation ratio alterations (eleocytes\/amoebocytes) were recorded in extruded coelomocytes. Complementarily, the use of coelomocytes to assess molecular level endpoints represented a relevant alternative for development of non-invasive biomarkers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241786,"idioma_id":5,"titulo":"COMPARACION DE NIVELES DE ALFA-1 ANTITRIPSINA EN PACIENTES CON Y SIN SINDROME DE DISTRES RESPIRATORIO AGUDO EN TERAPIA INTENSIVA","resumen":"COMPARACION DE NIVELES DE ALFA-1 ANTITRIPSINA ENPACIENTES CON Y SIN SINDROME DE DISTRES RESPIRATORIOAGUDO EN TERAPIA INTENSIVAAB ROJAS(1), M ANDREOTTI(1), D MENDIETA(1), D REYNOSO(1), R MELÉNDEZ(1), N LUNA(1), JC VERGOTTINI(1)(1) Hospital Nacional De Clinicas De Cordoba.HospitalNacional De Clínicas.Introducción: La Alfa 1 Antitripsina (AAT) modula la respuesta inflamatoriadel endotelio pulmonar al Factor de Necrosis Tumoral Alfa(FNT-&#945;), y disminuye la concentración de citoquinas proinflamatorias,atenuando la inflamación, la injuria tisular y la fibrosis (1,2,5).En el SDRA (Síndrome de Distres Respiratorio Agudo) la elevaciónde AAT se eleva en relación a la acción inflamatoria mediada porcitoquinas (2,3,4). La determinación de AAT no es costosa, a diferenciade las citoquinas.Objetivos: Determinar y comparar los niveles de AAT plasmáticaentre pacientes sin SDRA y con SDRA e identificar la correlaciónentre otras patologías y los niveles de AAT.Material y Método: Se incluyeron 28 pacientes. 14 con diagnósticode SDRA, que se compararon con un lote control (sin distres) (n=14).A todos se les consignó la edad, sexo, antecedentes patológicos,diagnóstico de ingreso, nivel de PaO2\/FiO2 (Presión arterial de O2\/Fracción Inspirada de O2), Score de Murray, de SOFA (SequentialOrgan Failure Assessment) y tiempo de AVM (Asistencia VentilatoriaMecánica). En las muestras sanguíneas se determinó el nivel deAAT, el valor de Glóbulos Blancos y los valores de Gases Arteriales .Resultados: La edad promedio del Grupo con distres fue de 59±5,41años y del grupo control 60±5,56 años (NS).Los diagnósticos de ingresoa Terapia Intensiva en el grupo distres fueron: 35,71% conNAC (Neumonía Aguda de la Comunidad), 14,29% NAVM (NeumoníaAsociada a la Ventilación Mecánica) y el 14,29% sepsis. Lamedia de AAT plasmática del grupo con SDRA fue de 322±22,4 (R152-440) mgr\/dl y del grupo control de 133,6 ± 13,46 (R 64-240)mgr\/dl (p <0,01).Conclusiones: Los niveles de AAT plasmática en los pacientes conSDRA fueron mayores y se correlacionaron con SDRA. La AAT es unmarcador de inflamación sistémico indirecto.-Bibliografía:1) Lockett DA, Kimani S, Ddungu W, Wrenger S, Tuder RM, JanciauskieneSM, et al. &#945;-1 Antitrypsin Modulate Lung EndothelialCell Inflamatory Responses to TNF-&#945;. Am J Respir Cell Mol Biol2013;49:143-150.2) Stoller JK, Aboussouan LS. A review of alpha-1 Antitrypsin Deficiency.Am J Respir Crit Care Med 2012;185:246-259.3) Fujishima S. Pathophysiology and biomarkers of acute respiratorydistress syndrome. J Intensive Care 2014;2:32.4) Koh Y. Update in acute respiratory distress syndrome. J IntensiveCare 2014;2:2.5) Griese M, Latzin P, Kappler M, Weckerle K, Heinzlmaier, T, BernhardtT, et al. Alpha-1 Antitrypsin Inhalation reduces airway inflammationin cistic fibrosis patients. Eur Respir J 2007;29:240-250.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241787,"idioma_id":4,"titulo":"Microbiological quality of Argentinian paprika","resumen":"The aim of this study was to evaluate the microbiological quality of paprika produced in the northern region of Argentina. Microbiological analysis were carried out for the enumeration of total aerobic mesophilic bacteria, coliforms, yeasts and moulds, and detection of Salmonella in samples obtained from different local producers during three consecutive years. The mycobiota was identified with special attention to the mycotoxigenic moulds. Standard plate counts of aerobic mesophilic bacteria ranged from 2.7×105 to 3.7×107 CFU\/g. Coliform counts ranged from <10 to 8.1×104 CFU\/g. Salmonella was not detected in any of the samples tested. Fungal counts (including yeasts and moulds) ranged between 2×102 and 1.9×105 CFU\/g. These results showed a high level of microbial contamination, exceeding in several samples the maximum limits set in the international food regulations. The study of the mycobiota demonstrated that Aspergillus was the predominant genus and A. niger (potential producer of ochratoxin A) the most frequently isolated species, followed by A. flavus (potential producer of aflatoxins). Other species of potential toxigenic fungi such as A. ochraceus, A. westerdijkiae, Penicillium chrysogenum, P. crustosum, P. commune, P. expansum and Alternaria tenuissima species group were encountered as part of the mycobiota of the paprika samples indicating a risk of contamination with mycotoxins. A. westerdijkiae was isolated for the first time in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241789,"idioma_id":4,"titulo":"Inter-annual variability in otolith chemistry of catfish Genidens barbus from South-western Atlantic estuaries","resumen":"The catfish Genidens barbus is a commercial species from South America. The aim of the present study was to examine the inter-annual variability in estuary-specific chemical signatures of otolith cores (Ba:Ca, Mg:Ca, Mn:Ca, Sr:Ca and Zn:Ca ratios) for three estuaries from Argentina and Brazil where adults were collected over multiple years. Secondarily, we evaluated whether the percentages of classification of individuals to their natal origin place are affected by the grouping of several cohorts. Most element:Ca ratios were not significantly different among year cohorts. Results from PERMANOVA revealed significant differences in the multi-element signatures of the otolith core between cohorts for the Plata River estuary (PR) (P ¼ 0.006) and the Patos Lagoon (PL) (P ¼ 0.03), while no significant differences (P ¼ 0.9) were found for Paranagua´Bay (PB). The percentages of spatial classification (discriminant function analyses) decreased to between 15.5 and 25% for PR and PL when cohorts were grouped. This work makes it clear that the temporal variation in the chemical signature of the adult catfish otolith core can greatly affect the percentages of spatial classification.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241790,"idioma_id":4,"titulo":"Identification of potential fish stocks and lifetime movement patterns of Mugil liza Valenciennes 1836 in the Southwestern Atlantic Ocean","resumen":"The mullet Mugil liza is the Mugilidae that lives southernmost in the western Atlantic Ocean. Knowledge about migration, movements and identification of stocks of this important fishery resource is scarce. Thus, we aim tostudy movement patterns and to identify the presence of different fish stocks in the southwestern region of the Atlantic Ocean, using cumulative otolith shape morphometric and microchemical analyses of sagittae otoliths.Specimens (n =99) were obtained in four coastal areas: Paranaguá Bay in Brazil, Samborombón Bay, Mar Chiquita Coastal Lagoon, and San Blas Bay in Argentina. Otolith shape indices (circularity, rectangularity, aspect ratio, percentage occupied by sulcus, ellipticity and form factor) were used for stock identification analysis; and otolith microchemistry using LA-ICP-MS (Sr\/Ca and Ba\/Ca ratios chronological variation) was used for both the analysis of movement behaviors and the identification of fish stocks (otolith edge ratios). Morphometrical indices did not reveal a clear separation among areas. San Blas bay individuals presented otoliths tending to be longer than wider, with a more elliptic shape than the otoliths from other studied areas; also, this area did not share individuals with the most northern one, Paranaguá Bay in Brazil. The analysis of microchemical lifetime profiles revealed three types of behavior pattern: Type I: most frequent use of estuarine environments; Type II: afluctuating behavior between estuarine and sea\/high salinity waters; Type III: most frequent use of sea\/high salinity habitats. Otolith edge analysis did not reveal differences among Sr\/Ca and Ba\/Ca ratios for the different areas. Thus, it cannot be assured that there is more than one stock in the studied region. Mugil liza revealed different environmental migratory behaviors in the Southwestern Atlantic Ocean showing a facultative use of estuarine waters; hence, the species appears to be mostly coastal with the use of low estuaries, as seen also by the Sr\/Ca otolith cores ratios; differing from the general mugilid behavior previoulsy described.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241791,"idioma_id":4,"titulo":"Otolith morphometry and microchemistry as habitat markers for juvenile Mugil cephalus Linnaeus 1758 in nursery grounds in the Valencian community, Spain","resumen":"The aim of this study was to identify and characterize juvenile Mugil cephalus (flatheadgrey mullet) habitats in the Valencian community by means of otolith morphometryand microchemistry. Specimens (total length: 250?350 mm) were obtained fromOctober 2011 to March 2012 with gill nets in two protected wetlands: the ParqueNartural de l?Albufera de Valencia (AV) (n = 45), a Mediterranean lake; and the ParqueNatural Salinas de Santa Pola (SP) (n = 37), a coastal salt marsh. Otolith shape indices(circularity, rectangularity, aspect ratio, surface occupied by sulcus, ellipticity and formfactor) and microchemistry (Sr\/Ca and Ba\/Ca ratios) were measured and compared asarea markers. The chemical composition of the water in both areas was also obtained.Morphometric results showed, by an ANOVA with Bonferroni contrasts, that saccularotoliths from AV individuals had more edge complexity, hence a higher circularityindex (p &lt; .001), but that there was less otolith percentage occupied by the sulcus(p &lt; .001). When analyzing the morphometric variables simultaneously, both sites differedsignificantly (Hotelling?s T2 &lt; 0.001). A paired t-testamong sites of the microchemicalvariables showed that otoliths of AV presented higher values of Ba\/Ca ratiosand lower Sr\/Ca ratios (p &lt; .001). This coincides with water values obtained and couldbe associated with the low salinity observed in the lake. The opposite pattern wasobserved in SP, both for otolith and water samples, this being associated with thehigh-salinity waters of the area. Results obtained in the present research suggest, bythe use of otolith morphometry and microchemistry, that the nursery grounds of juvenileM. cephalus in the Valencian community could be differentiated. Even thoughhabitats could be separated using otolith morphometry, only a few of the studiedshape indices were important in area differentiation. Nevertheless, the use of bothmethodologies simultaneously could be robust habitat markers for this species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241792,"idioma_id":5,"titulo":"Fluvio-marine travelers from South America: cyclic amphidromy and freshwater residency, typical behaviors in Genidens barbus inferred by otolith chemistry","resumen":"Catfish Genidens barbus is a commercially fished species from the south-western Atlantic Ocean. Overfishing of this species during the last few years has caused a collapse of fisheries and in turn has led to a ban of its exploitation. In order to identify the migratory patterns of this species in four migration corridors from South America, we determined the Sr:Ca and Ba:Ca ratios in otoliths, by Laser Ablation Inductively Coupled PlasmaMass Spectrometry (LA-ICPMS). Sr:Ca and Ba:Ca ratios range between 0.90 and 9.83 mmol\/mol (mean ± standard deviation: 3.86 ± 1.05 mmol\/mol) and between 0.00013 and 0.10 mmol\/mol (mean ± SD: 0.0094 ± 0.0160 mmol\/mol), respectively. Three types of amphidromous and cyclical (annual) patterns that include the use of freshwater, estuarine and marine environments are detected. Resident freshwater fish (6.5%) are found only in Patos Lagoon. Depending on the study site, between 18 and 45% of the analyzed fishpopulation were spawned in freshwater, while the rest were spawned in estuarine waters. The change-point analysis shows a positive correlation between changes in the transects of Sr:Ca and Ba:Ca ratios (r =0.63, p =0.0001), whereas the Kruskal-Wallis test shows no significant differences in the number of changes in transects of the Sr:Ca ratio between sampling sites (H=2.1, p=0.53). Only for Patos Lagoon the analyses show a significantly higher number of changes for the Ba:Ca ratio (H=9.1, p=0.03). The data indicate that the average number of movements among environments is similar between the four corridors. The number of changes of the Ba:Ca ratio appears to be higher and more variable in relation to the Sr:Ca ratio, indicating that the former could be more sensitive to environmental changes. In conclusion, this work describes for the first time, annual amphidromous migrations and dependence on freshwater for different fluvial-marine systems. The understanding of the habitat use will help design species and estuarine-specific management actions with the ultimate goal of recovering fisheries.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241793,"idioma_id":4,"titulo":"Environmental migratory patterns, and stock identification of Mugil cephalus in the Spanish Mediterranean Sea, by means of otolith microchemistry","resumen":"The Flathead grey mullet, Mugil cephalus is the most globally-distributed Mugilidae species and its migrations and movement patterns have been studied globally but not in-depth in the Mediterranean region. Thus, the present study aimed: (1) to identify migratory patterns throughout the life-history of the Mugil cephalus in different Spanish Mediterranean wetlands, and (2) to study the presence of potential fish stocks of the species in the region by means of otolith microchemistry. Specimens (n = 43) were obtained in three wetlands: Parque Natural Delta de l?Ebro (DE), a stratified estuary; Parque Natural de l?Albufera de Valencia (AV), a Mediterranean lake; and Parque Natural Salinas de Santa Pola (SP), a coastal salt marsh. Otolith microchemistry was studied using LA-ICP-MS (chronologicalvariation of Sr:Ca and Ba:Ca ratios). The analysis of lifetime profiles revealed four behavioral patterns: Type I: most frequent use of estuarine environments (estuarine resident); Type II: freshwater behaviour during early life history, moving though estuarine to marine waters at the end of their profile (freshwater migrant); Type III: estuarine water use in early life stages moving then towards sea waters (estuarine migrant); and Type IV: sea\/high salinity water habitat use during their entire lifetime (seawater resident). A Canonical Discriminant Analysis, using Sr:Ca and Ba:Ca ratios from core andedge as variables, assigned individuals to the detected patterns with high accuracy (Type I &gt; 95%; Type II and Type III &gt; 83%; and Type IV &gt; 88%). Moreover, two potential fish stocks were identified by the analysis of Sr:Ca otoliths-edge ratios: one in the Valencian Gulf, DE-AV areas presented similar ratios, and the other in the southern location, SP (higher Sr:Ca values). Mugil cephalus presented diverse life patterns on the Valencian Community Mediterranean coast. Different strategies could be identified by the used methodology: some particular to an area (Type IV-SP); others shared among areas, changing environments in different stages of their life. The presence of different fish stocks could be influenced by a mesoscale current phenomenon observed in the region associated with the Balearic front.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241794,"idioma_id":5,"titulo":"Influencia de las descargas industriales y domésticas de los asentamientos urbanos sobre el Río Uruguay entre los años 1998 y 2004.","resumen":"El Río Uruguay de 1800 km de longitud, tiene una cuenca que abarca una superficie de 339000 km2. En los últimos 508 km del río, es el límite fronterizo entre la República Argentina y la República Oriental del Uruguay. En este tramo se asientan siete ciudades importantes; de norte a sur se encuentran en el lado argentino Concordia, Colón, Concepción del Uruguay y Gualeguaychú, y del lado Salto, Paysandú y Fray Bentos. Estas ciudades han tenido un importante crecimiento en los últimos 50 años, sin embargo, la influencia de las mismas sobre el río no ha sido estudiada.En este trabajo analizaremos la influencia de estas descargas sobre el Río Uruguay en el periodo 1998-2004 y compararemos los valores de los parámetros fisco-químicos y biológicos obtenidos, con los niveles guía propuestos por la Comisión Administradora del Río Uruguay (CARU) y la línea base del cauce principal. Con ese objetivo, se recopilaron los datos de 12 campañas, realizadas en los meses de invierno y primavera. Los parámetros físico-químicos determinados fueron: conductividad, pH, oxígeno disuelto, alcalinidad, dureza, sólidos totales disueltos, nitratos, nitritos, amonios, fosfatos, los iones mayoritarios (Na+, K+; Ca2+, Mg2+, Cl-, SO42-) y los (Cd2+, Cc2+, Cr3+ y Pb2+); y el parámetro biológico determinado fue bacterias coliformes fecales. Todos estos parámetros fueron analizados por métodos normatizados. Los resultados evidencian que las siete ciudades asentadas en las márgenes del Río Uruguay producen diferente influencia sobre la calidad de las aguas costeras del río. Los sitios de muestreo asociados a las ciudades de Concordia en la República Argentina y de Paysandú en la República Oriental del Uruguay son los que poseen valores superiores a los parámetros recomendados por la CARU para garantizar la calidad del agua con destino a abastecimiento público con tratamiento convencional. Es de destacar que si bien se observa una influencia importante de las descargas de las siete ciudades sobre el río, la misma es moderada debido a su capacidad autodepuradora.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241795,"idioma_id":4,"titulo":"Otolith edge fingerprints as approach for stock identification of Genidens barbus","resumen":"The purpose of this paper is to assess the use of multi-elemental otolith fingerprints as a tool todelimit catfish Genidens barbus fish stocks in four estuaries from the southwestern Atlantic&nbsp;Ocean. Barium:Calcium (Ca), Magnesium:Ca, Manganese:Ca, Sodium:Ca and Strontium:Ca&nbsp;ratios in the otolith edge were determined by LA-ICPMS. PERMANOVA analysis reveal&nbsp;significant differences in the multi-element signatures among estuaries (p=0.0001-0.002).&nbsp;Reclassification rates of quadratic discriminant analysis are high, averaging 89.9 % (78-100%).&nbsp;The new data presented here show that the otolith chemistry is a potential tool for stock&nbsp;identification, and indicates the presence of at least four stocks which should probably be handled&nbsp;independently.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241796,"idioma_id":4,"titulo":"Morphological and morphometric changes of sagittae otoliths related to fish growth in three Mugilidae species","resumen":"The aim of this study was to analyze morphologic and morphometric changes of sagittaeotoliths throughout the growth of three mullets: Mugil liza, Mugil cephalus and Lizaramada. Fish were collected seasonally between October 2011 and April 2014, andthree methods were used: regression analysis of traditional biometric characters; morphologicalanalysis for group identification; and morphometrical analysis of shape indicesamong groups (circularity, rectangularity, aspect ratio and percentage occupied bythe sulcus). In all species, dependence of standard length on otolith length and heightwere best described as power functions. Two morphological groups were identifiedfor M. liza and M. cephalus, while three for L. ramada. Morphological changes were supportedby morphometry differences only for the first two species. Smaller size specimensof M. liza had more rectangular otoliths with more percentage covered by thesulcus while bigger fish tended to have a more circular shape. For M. cephalus smallersize fish had a more elliptical shape. The observed changes may be reflecting life historychanges, related to habitat or dietary shifting.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241797,"idioma_id":4,"titulo":"Migration and brackish environment use of Prochilodus lineatus (Characiformes: Prochilodontidae) inferred by Sr:Ca ratio transects of otolith","resumen":"The streaked prochilod, Prochilodus lineatus, represents the most important fishery in the La Plata Basin (South America). Our objective was to analyze brackish environment use by the streaked prochilod captured from Paraná and Uruguay rivers. To accomplish this, lapillus otolith sections were analyzed for Sr:Ca with laser ablation-inductively coupled plasma-mass spectrometry (LA ICP-MS) to infer habitat use of fish. To the interpretation of transects, a threshold that represents the transition between freshwater and brackish environments was calculated using the Sr:Ca ratio of the otolith edge of specimens captured in the first section of the La Plata Estuary (salinity &#8805; 0.5 PSU). The percentage of fish using the estuary was higher in the Paraná (37%) than the Uruguay River (5%). Change-point analysis showed that fish entered the estuary between 1 and 3 times throughout life at a wide range of ages (0-15 years). These incursions had no obvious periodicity. This information should be integrated into future management actions, which should also be specific to each area since migration patterns differ between the major rivers of the basin.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241799,"idioma_id":4,"titulo":"A note on the use of the Companion Solution (Dirichlet Green's function) on meshless boundary element methods","resumen":"Most implementations of meshless BEMs use a circular integration contours (spherical in 3D) embedded into a local interpolation stencil with the so-called Companion Solution (CS) as a kernel, in order to eliminate the contribution of the single layer potential. However, the Dirichlet Green´s Function (DGF) is the unique Fundamental Solution that is identically zero at any given close surface and therefore eliminates the single layer potential. One of the main objectives of this work is to show that the CS is nothing else than the DGF for a circle collocated at its origin. The use of the DGF allows the collocation at more than one point, permitting the implementation of a P-adaptive scheme in order to improve the accuracy of the solution without increasing the number of subregions. In our numerical simulations, the boundary conditions are imposed at the interpolation stencils in contact with the problem boundary instead of at the corresponding integration surfaces, permitting always the use of circular integration contours, even in regions near or in contact with the problem domain where the densities of the integrals are reconstructed from the interpolation formulae that already included the problem boundary conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241800,"idioma_id":4,"titulo":"ISOLATION OF SAPROPHYTIC LEPTOSPIRA SP. FROM A SELECTED ENVIRONMENTAL WATER SOURCE OF ARGENTINA","resumen":"Abstract Ten Leptospira sp. strains were isolated from water samples from Nievas stream,Olavarría, Buenos Aires province (Argentina). The isolates showed the typical motility and morphologyof the genus Leptospira under dark field microscopy, developing in liquid EMJH mediumafter eight days of incubation at 13 &#9702;C and 30 &#9702;C. All isolates were negative by the Multiple LocusVariable Number Tandem Repeat Analysis (MLVA). Molecular identification by 16S rRNA genesequencing identified all isolates as nonpathogenic leptospires. Four isolates showed a geneticprofile identical to that of the reference strain Leptospira biflexa serovar Patoc, and six isolatesrevealed sequence similarities within the 97---98% range, closely related to Leptospira yanagawaeand Leptospira meyeri, respectively. Strains ScialfaASA42, ScialfaASA45, ScialfaASA44,ScialfaASA47, ScialfaASA49, ScialfaASA50 and ScialfaASA51 possibly represent a novel species ofthe genus Leptospira. The sequence obtained from Strains ScialfaASA42 is available in GenBankunder Accession number KT160428.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241802,"idioma_id":5,"titulo":"Mujeres en la colección del MPBA  Sobre la exposición Ilustres desconocidas","resumen":"Durante los meses de febrero y marzo de 2017, tuvo lugar en La Plata la exposición Ilustres desconocidas, algunas mujeres en la colección del Museo Provincial de Bellas Artes ?Emilio Pettoruti?. La exposición se planteó como objetivo dar a conocer las producciones y la trayectoria de artistas mujeres que habían pasado desapercibidas en los discursos de la historia del arte argentino, a partir de un relato curatorial que permitiera plantear interrogantes respecto al lugar de las mujeres en la historia de la conformación de la colección y del museo. En este artículo revisamos algunos aspectos del trabajo de investigación que guió la curaduría de esa muestra.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241807,"idioma_id":5,"titulo":"La crítica de arte en las colecciones monográficas. Redes y circuitos panamericano e hispanomaericano","resumen":"Este trabajo se propone analizar los modos de intervención de la crítica de arte en la construcción de representaciones de arte argentino y americano a principios de los años cuarenta, en el marco del auge editorial y de las formaciones culturales forjadas en el país durante la Segunda Guerra Mundial.  Para ello examina el rol que ocupó la crítica en algunos proyectos editoriales instauradores de figuraciones y relatos historiográficos a comienzos del periodo. Desde esta perspectiva, el trabajo no intenta profundizar en la dimensión discursiva de los textos críticos, sino en la forma en que éstos se insertaron en las publicaciones. Con este fin pone el foco tanto en las estrategias editoriales y en las características materiales de las publicaciones, en los términos en que R. Chartier las define como objetos impresos, así como en las redes artístico-intelectuales y los circuitos culturales donde se inscribieron.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241809,"idioma_id":4,"titulo":"Three-dimensional temperature fields of the North Patagonian Sea recorded by Magellanic penguins as biological sampling platforms","resumen":"Temperature is a primary determinant of biogeographic patterns and ecosystem processes. Standard techniques to study the ocean temperature in situ are, however, particularly limited by their time and spatial coverage, problems which might be partially mitigated by using marine top predators as biological platforms for oceanographic sampling. We used small archival tags deployed on 33 Magellanic penguins (Spheniscus magellanicus), and obtained 21,070 geo-localized profiles of water temperature, during late spring of 2008, 2011, 2012 and 2013; in a region of the North Patagonian Sea with limited oceanographic records in situ. We compared our in situ data of sea surface temperature (SST) with those available from satellite remote sensing; to describe the three-dimensional temperature fields around the area of influence of two important tidal frontal systems; and to study the inter-annual variation in the three-dimensional temperature fields. There was a strong positive relationship between satellite- and animal-derived SST data although there was an overestimation by remote-sensing by a maximum difference of +2 °C. Little inter-annual variability in the 3-dimensional temperature fields was found, with the exception of 2012 (and to a lesser extent in 2013) where the SST was significantly higher. In 2013, we found weak stratification in a region which was unexpected. In addition, during the same year, a warm small-scale vortex is indicated by the animal-derived temperature data. This allowed us to describe and better understand the dynamics of the water masses, which, so far, have been mainly studied by remote sensors and numerical models. Our results highlight again the potential of using marine top predators as biological platforms to collect oceanographic data, which will enhance and accelerate studies on the Southwest Atlantic Ocean. In a changing world, threatened by climate change, it is urgent to fill information gaps on the coupled ocean-atmosphere system allowing to link the hydrothermal process to the at-sea distribution of top predators.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241810,"idioma_id":4,"titulo":"Jellyfish and other gelata as food for four penguin species &ndash; insights from predator-borne videos","resumen":"Jellyfish and other pelagic gelatinous organisms (?gelata?) are increasingly perceived as an important component of marine food webs but remain poorly understood. Their importance as prey in the oceans is extremely difficult to quantify due in part to methodological challenges in verifying predation on gelatinous structures. Miniaturized animal-borne video data loggers now enable feeding events to be monitored from a predator´s perspective. We gathered a substantial video dataset (over 350 hours of exploitable footage) from 106 individuals spanning four species of non-gelatinous-specialist predators (penguins), across regions of the southern oceans (areas south of 30°S). We documented nearly 200 cases of targeted attacks on carnivorous gelata by all four species, at all seven studied localities. Our findings emphasize that gelatinous organisms actually represent a widespread but currently under-represented trophic link across the southern oceans, even for endothermic predators, which have high energetic demands. The use of modern technological tools, such as animal-borne video data loggers, will help to correctly identify the ecological niche of gelata.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241811,"idioma_id":4,"titulo":"Long necks enhance and constrain foraging capacity in  aquatic vertebrates","resumen":"Highly specialised diving birds display substantial dichotomy in neck length with, for example, cormorants and anhingas having extreme necks while penguins and auks have minimized necks. We attached acceleration loggers to Imperial Cormorants Phalacrocorax atriceps and Magellanic Penguins Spheniscus magellanicus, both foraging in waters over the Patagonian shelf, to examine the difference in movement between their respective heads and bodies in an attempt to explain this dichotomy. The penguins had head and body attitudes and movements that broadly concurred throughout all phases of their dives. In contrast, although the cormorants followed this pattern during the descent and ascent phases of dives, during the bottom (foraging) phase of the dive, the head angle differed widely from that of the body and its dynamism (measured using vectorial dynamic acceleration - VeDBA) was over 4 times greater. A simple model indicated that having the head on an extended neck would allow these cormorants to half the energy expenditure that they would expend if their body moved in the way their heads did. This apparently energy-saving solution is likely to lead to greater heat loss though and would seem tenable in slow-swimming species since the loss of streamlining that it engenders would make it detrimental for fast-swimming taxa such as penguins.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241812,"idioma_id":5,"titulo":"Lo culto y lo popular: conocimientos y prácticas médicas para el abordaje de la salud\/enfermedad","resumen":"Objetivos: analizar, desde la percepción de cinco actores culturales residentes en la localidad de Guerrero, como confluyen la medicina letrada (lo culto) y la medicina tradicional (lo popular) para el restablecimiento de la salud.  Materiales y métodos: se utilizó una metodología cualitativa basada en un paradigma interpretativo, descriptivo, transversal y prospectivo. La recolección de datos fue realizada mediante entrevistas sobre cinco informantes claves residentes en la localidad de Guerrero de la provincia de Jujuy. La selección se realizó siguiendo un muestreo por conveniencia. Resultados y conclusiones: Se determinaron tres categorías de análisis: percepción de la enfermedad; tipo y descripción de las enfermedades místicas y no místicas; métodos de diagnóstico y terapéuticas. Se concluye que existe una complementariedad entre medicina científica y medicina tradicional para restablecer la salud realizada por los mismos sujetos que están atravesando por una situación de enfermedad. En esta búsqueda por recuperar su salud, emerge el saber popular, entrando en escena una terapéutica rica en farmacopea herbolaria y no herbolaria, y elementos religiosos. Ello demuestra que pese al gran avance de la medicina científica, en nuestra provincia aún perdura una cultura Folk, donde la medicina popular puede considerarse la expresión más pura del medio cultural.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241813,"idioma_id":5,"titulo":"Dos registros de Agaricales (Basidiomycota) exóticos en bosques nativos de la Patagonia argentina","resumen":"Inocybe sindonia (Fr.) P. Karst. y Amanita rubescens Pers. son especies típicamente asociadas a bosques de Pseudotsuga menziesii (Mirb.) Franco y Pinus radiata D. Don respectivamente. Se reporta por primera vez su presencia en Argentina en bosques de Nothofagus de la Patagonia andina como resultado de la invasión de especies forestales introducidas como recurso maderero. I. sindonia fue colectado en bosques de N. dombeyi (Mirb.) Oerst. y A. rubescens en bosques de N. pumilio (Poepp. & Endl.) Krasser en áreas protegidas con invasión evidente de coníferas exóticas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241814,"idioma_id":4,"titulo":"Preventable Ischaemic Heart Disease and Stroke Deaths Attributable to Insufficient Physical Activity: A Comparative Risk Assessment Analysis in the Argentinian Population","resumen":"Background: Physical inactivity is estimated to be the 9thleading risk factor for all-cause mortality in Argentina. However,its impact on specific causes of death has not beenevaluated using nationally representative data.Design: We conducted a comparative risk assessment analysisto estimate the proportion and number of IHD and strokedeaths in Argentina that are attributable to different non-optimallevels of physical activity (PA).Methods: We obtained data on prevalence of different levelsof PA from the Argentinian National Survey of Risk Factorsin 2013 and used relative risks for IHD and stroke mortalityfrom previous meta-analyses. Deaths due to IHD andstroke, by age and sex, were obtained from the nationaldeath registry for the year 2010. We considered 4 categoriesof PA based on the metabolic equivalent tasks per minuteper week (METs.min\/week): inactive, &lt; 600, &#8805; 600 to &lt;1,600 and &#8805; 1,600.Results: In Argentina, 76.8% (CI 95%; 75.8%-77.7%) of thepopulation older than 30-years-old engaged in &lt; 1,600METs.min\/week. This level of insufficient activity contributedto 26% of CVD deaths (IHD or stroke) (11,234 of 43,796deaths; 6,013 in men and 5,221 in women); 29% (7,292) ofIHD deaths; and 21% (3,942) of stroke deaths. The impactof insufficient PA was higher in individuals younger than70-years-old due to stronger associations between non-optimalPA and mortality from IHD and stroke.Conclusions: A non-optimal level of PA contributes substantiallyto the mortality burden of cardiovascular diseases in Argentina,especially in individuals under 70-years-old. More substantialresources should be directed toward enhancing builtand social environments which are essential to effectively increasePA, to improve health-related quality of life and reducethe burden of cardio-metabolic diseases in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241815,"idioma_id":4,"titulo":"TGF-b pro-oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with","resumen":"Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes and oligodendrocytes (OLs) throughout life. Notch and transforming growth factor beta 1 (TGF-&#946;) signaling pathways play critical roles in controlling these cell fate decisions. TGF-&#946; has been previously shown to exert proneurogenic effects on hippocampal and subventricular zone (SVZ) NPCs in vitro and to interact with Notch in different cellular types. Therefore, the aim of our work was to study the effect of TGF-&#946; on adult rat brain SVZ NPC glial commitment andits interaction with Notch signaling. Initial cell characterization revealed a large proportion of Olig2+, Nestin+ and GFAP+ cells, a low percentage of PDGFR&#945;+ or NG2+ cells, and less than 1% Tuj1+ cells. Immunocytochemical analyses showed a significant increase in the percentage of PDGFR&#945;+, NG2+ and GFAP+ cells upon four-day TGF-&#946; treatment, which demonstrates the pro-gliogenic effect of thisgrowth factor on adult brain SVZ NPCs. Real-time polymerase chain reaction (PCR) analyses showed that TGF-&#946; induced the expression of Notch ligand Jagged1 and downstream gene Hes1. Notch signaling inhibition in cultures treated with TGF-&#946; produced a decrease in the proportion of PDGFR&#945;+ cells, while TGF-&#946; receptor II (T&#946;RII) inhibition also rendered a decrease in the proportion of PDGFR&#945;+ cells, concomitantly with a decrease in Jagged1 levels. These findings demonstrate the participation of Notch signaling in TGF-&#946; effects and illustrate the impact of TGF-&#946; on glial cell fate decisions of adult brain SVZ NPCs, as well as on oligodendroglial progenitor cell (OPC) proliferation and maturation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241818,"idioma_id":5,"titulo":"CRÍTICA FEMINISTA SOBRE LA NOCIÓN DE LA BUENA MADRE","resumen":"El presente artículo es parte de la investigación de Tesis de Maestría en Estudios Culturales y tiene comopropósito socializar un breve recorrido sobre la crítica feminista a la institución familiar y a la nociónde la buena madre en el sistema patriarcal. Revisión teórica que permite traer a la luz algunos de losdebates que se dieron al interior de las teorías feministas desde finales del Siglo XVIII sobre el tópicode la maternidad. Así, diferentes autores y autoras problematizan de manera crítica las construccionesy los efectos de los diversos discursos sociales sobre las mujeres, entre los que se destacan los discursossobre la maternidad. Las interpretaciones feministas a las que se aluden en el presente trabajo, handefinido a la noción de maternidad como una construcción discursiva apoyada en distintas disciplinas-el saber teológico y médico en un comienzo, y luego la demografía, la psicología, entre otros- y en institucionesdisciplinarias que han ido modificándose a lo largo de la historia estableciendo así, para cadaperiodo histórico, lo que se considera una buena o mala madre en función de lo que se estime negativoo positivo para cada época. En este sentido, se recorren las principales críticas teóricas feministas quepusieron bajo la lupa los aspectos históricos y filosóficos que contribuyeron a configurar el modo hegemónicode producir maternidad y se revisan los discursos sociales y políticos que coadyuvaron para laconsolidación contemporánea de la institución familiar.Palabras clave: Teorías feministas, Maternidad, Familia, Patriarcal","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241819,"idioma_id":4,"titulo":"Dialectical inferences in the ontogenesis of social representations","resumen":"This article deals with a possible collaboration between two disciplines: developmental psychology and the theory of Social Representations (SR). The latter takes the study of the ontogenesis of social representations as a central issue, even though the explanation of this process is still inadequate. The objective of this paper is to analyse the potential found in the category of dialectical inferences, as formulated by Piagetian psychology, to act as a tool in explaining the psychological dynamics implied in the ontogenesis of social representations. We first present dialectics in the sense of an inferential process in the individual?s construction of new meanings or concepts. Secondly, we analyse the research that has studied the ontogenetic processes of SR, interpreting its results by appealing to dialectical inferences. Lastly, we examine the theoretical meaning of the research on the ontogenesis of SR.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241822,"idioma_id":4,"titulo":"Development of a simple and economical diagnostic test for canine leishmaniasis","resumen":"Visceral leishmaniasis is a public health problem worldwide. The early diagnosis in dogs is crucial, since they are an epidemiologically relevant reservoir of the disease. The aim of a field study is to early identify the disease allowing rapid intervention to reduce its effects. We propose an immunoagglutination test as a visual in situ method for diagnosis of canine visceral leishmaniasis. Latex-protein complexes were sensitized by covalent coupling of a chimeric recombinant antigen of Leishmania spp. onto polystyrene latex with carboxyl functionality. The reaction time and the antigen concentration under which the immunoagglutination assay shows greater discrimination between the responses of a positive control serum and a negative control serum were determined. Then, the latex-protein complexes were evaluated as a visual diagnostic tool with a panel of 170 sera. The test may be read between 2 and 5 min and can be performed even using sera with elevated concentration of lipids, bilirubin or with variable percentage of hemolysis. The sensitivity, the specificity and the diagnostic accuracy were 78%; 100% and >80%, respectively. The visual immunoagglutination test is of potential application as a method for field studies because it shows results in less than 5 min, it is easy to implement and does not require sophisticated equipment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241823,"idioma_id":4,"titulo":"Global analysis of mannitol 2 dehydrogenase in Lactobacillus reuteri CRL 1101 during mannitol production through enzymatic, genetic and proteomic approaches","resumen":"Several plants, fungi, algae, and certain bacteria produce mannitol, a polyol derived from fructose. Mannitol has multiple industrial applications in the food, pharmaceutical, and medical industries, being mainly used as a non-metabolizable sweetener in foods. Many heterofermentative lactic acid bacteria synthesize mannitol when an alternative electron acceptor such as fructose is present in the medium. In previous work, we reported the ability of Lactobacillus reuteri CRL 1101 to efficiently produce mannitol from sugarcane molasses as carbon source at constant pH of 5.0; the activity of the enzyme mannitol 2-dehydrogenase (MDH) responsible for the fructose conversion into mannitol being highest during the log cell growth phase. Here, a detailed assessment of the MDH activity and relative expression of the mdh gene during the growth of L. reuteri CRL 1101 in the presence of fructose is presented. It was observed that MDH was markedly induced by the presence of fructose. A direct correlation between the maximum MDH enzyme activity and a high level of mdh transcript expression during the log-phase of cells grown in a fructose-containing chemically defined medium was detected. Furthermore, two proteomic approaches (2DE and shotgun proteomics) applied in this study confirmed the inducible expression of MDH in L. reuteri. A global study of the effect of fructose on activity, mdh gene, and protein expressions of MDH in L. reuteri is thus for the first time presented. This work represents a deep insight into the polyol formation by a Lactobacillus strain with biotechnological potential in the nutraceutics and pharmaceutical areas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241824,"idioma_id":4,"titulo":"Food prospects of selenium enriched-Lactobacillus acidophilus CRL 636 and Lactobacillus reuteri CRL 1101","resumen":"Selenium, which is present as SeCys in selenoproteins, is involved in cancer prevention, thyroid functioning, and pathogen inhibition. Lactobacilli can biotransform inorganic Se into seleno-amino acids. Growth, Se accumulation and seleno-amino acid formation by Lactobacillus acidophilus CRL636 and L. reuteri CRL1101 in a Se-supplemented medium were studied. Moreover, survival of Se-enriched strains to different pH values and bile salts was analyzed. L. acidophilus CRL636 showed low growth rate in the presence of Se while differences were less evident for L. reuteri CRL1101, which displayed higher amounts of intracellular SeCys and SeMet than the CRL636 strain. Interestingly, both lactobacilli could produce Se-nanoparticles. Se-enriched lactobacilli showed lower growth rates than non-Se exposed cells. The adverse effect of bile salts and the ability to survive at pH 4.0 diminished for the Se-enriched L. reuteri strain. The studied lactobacilli could be used as Se-enriched probiotics or as a vehicle for manufacturing Se-containing fermented foods.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241825,"idioma_id":4,"titulo":"Enhanced mannitol biosynthesis by the fruit origin strain Fructobacillus tropaeoli CRL 2034","resumen":"Mannitol is a natural low-calorie sugar alcohol produced by certain (micro)organisms applicable in foods for diabetics due to its zero glycemic index. In this work, we evaluated mannitol production and yield by the fruit origin strain Fructobacillus tropaeoli CRL 2034 using response surface methodology with central composite design (CCD) as optimization strategy. The effect of the total saccharide (glucose + fructose, 1:2) content (TSC) in the medium (75, 100, 150, 200, and 225&nbsp;g\/l) and stirring (S; 50, 100, 200, 300 and 350&nbsp;rpm) on mannitol production and yield by this strain was evaluated by using a 22 full-factorial CCD with 4 axial points (&#945;&nbsp;=&nbsp;1.5) and four replications of the center point, leading to 12 random experimental runs. Fermentations were carried out at 30&nbsp;°C and pH&nbsp;5.0 for 24&nbsp;h. Minitab-15 software was used for experimental design and data analyses. The multiple response prediction analysis established 165&nbsp;g\/l of TSC and 200&nbsp;rpm of S as optimal culture conditions to reach 85.03&nbsp;g\/l [95% CI (78.68, 91.39)] of mannitol and a yield of 82.02% [95% CI (71.98, 92.06)]. Finally, a validation experiment was conducted at the predicted optimum levels. The results obtained were 81.91&nbsp;g\/l of mannitol with a yield of 77.47% in outstanding agreement with the expected values. The mannitol 2-dehydrogenase enzyme activity was determined with 4.6-4.9&nbsp;U\/mg as the highest value found. To conclude, F. tropaeoli CRL 2034 produced high amounts of high-quality mannitol from fructose, being an excellent candidate for this polyol production","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241826,"idioma_id":4,"titulo":"Soymilk fermentation by Enterococcus faecalis VB43 leads to reduction in the immunoreactivity of allergenic proteins &beta;-conglycinin (7S) and glycinin (11S)","resumen":"Food allergies represent a serious problem affecting human health and soy proteins rank among the most allergenic proteins from food origin. The proteolytic enzymes produced by lactic acid bacteria (LAB) can hydrolyse the major allergens present in soybean, reducing their immunoreactivity. Many studies have reported the ability of LAB to ferment soy-based products; while the majority of them focus on the improvement of the sensory characteristics and functionality of soy proteins, a lack of information about the role of lactic fermentation in the reduction of immunoreactivity of these proteins exists. The aim of the present study was to evaluate the capability of the proteolytic strain Enterococcus faecalis VB43 to hydrolyse the main allergenic proteins present in soymilk and to determine the immunoreactivity of the obtained hydrolysates. Sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) results of fermented soymilk demonstrated complete hydrolysis of the &#946;-subunit from &#946;-conglycinin and the acidic polypeptide from glycinin. Reversed phase high performance liquid chromatography (RP-HPLC) analysis of the peptides released after hydrolysis revealed the appearance of new peptides and the disappearance of non-hydrolysed proteins, indicating extensive hydrolysis of the substrate. Results from competitive enzyme-linked immunosorbent assay (ELISA) tests clearly indicated a reduction in the immunoreactivity (more than one logarithmic unit) in the fermented sample as compared to the non-fermented control. Our results suggest that the soymilk fermented by E. faecalis VB43 may induce lower allergic responses in sensitive individuals. The strain E. faecalis VB43 may be considered as an excellent candidate to efficiently reduce the immunoreactivity of soymilk proteins.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241827,"idioma_id":4,"titulo":"YebC, a putative transcriptional factor involved in the regulation of the proteolytic system of Lactobacillus","resumen":"The proteolytic system of Lactobacillus plays an essential role in bacterial growth, contributes to the flavor development of fermented products, and can release bioactive health-beneficial peptides during milk fermentation. In this work, a genomic analysis of all genes involved in the proteolytic system of L. delbrueckii subsp. lactis CRL 581 was performed. Genes encoding the cell envelope-associated proteinase, two peptide transport systems, and sixteen peptidases were identified. The influence of the peptide supply on the transcription of 23 genes involved in the proteolytic system of L. delbrueckii subsp. lactis was examined after cell growth in a chemically defined medium (CDM) and CDM supplemented with Casitone. prtL, oppA 1, optS, optA genes as well as oppDFBC and optBCDF operons were the most highly expressed genes in CDM; their expression being repressed 6- to 115-fold by the addition of peptides. The transcriptional analysis was confirmed by proteomics; the up-regulation of the PrtL, PepG, OppD and OptF proteins in the absence of peptides was observed while the DNA-binding protein YebC was up-regulated by peptides. Binding of YebC to the promoter region of prtL, oppA 1, and optS, demonstrated by electrophoretic mobility shift assays, showed that YebC acts as a transcriptional repressor of key proteolytic genes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241828,"idioma_id":4,"titulo":"Associations between dietary patterns and serum lipids, apo and C-reactive protein in an adult population: evidence from a multi-city cohort in South America","resumen":"Several previous epidemiological studies from developed countries have shown that an unhealthy dietary pattern affects plasma lipid levels andinflammation biomarkers. We assessed the cross-sectional associations between dietary patterns and cardiovascular risk factors among 961adults from a multi-city cohort in South America. We conducted a principal component analysis to derive dietary patterns. As outcomes, weexamined plasma levels of apo A-I, apo B, high-sensitivity C-reactive protein (hs-CRP), LDL-, HDL- and serum total cholesterol and TAG. Thecrude and adjusted changes in each outcome were estimated for quartiles of dietary patterns using multivariable linear regression models. Theprudent pattern (PP) characterised by higher intake of fruits, vegetables, fish, seafood, whole cereal and low-fat dairy products was associatedwith reduced plasma concentrations of apo B (&#8722;8·5mg\/l), total cholesterol (&#8722;18·8 mg\/dl) and LDL-cholesterol (&#8722;16·5mg\/dl) and hs-CRP(&#8722;1·6mg\/l) in men. In women also reduced plasma concentrations of apo B (&#8722;6·6mg\/l), total (&#8722;12·0mg\/dl) and LDL (&#8722;9·3mg\/dl). The ?Westernlike?pattern characterised by higher intake of eggs, pastry and cakes, pizza, snacks, refined grains, red meat, vegetable oils and poultry was notsignificantly associated with any of the selected serum lipid or inflammatory biomarkers. The explained variances were 10·3 and 7·4%,respectively. The PP was associated with better lipid profile, mainly lower atherogenic particles (apo B) and LDL-cholesterol and serum totalcholesterol. This study provides possible evidence of a prudent diet in South American populations to help reduce the burden of CVD.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241829,"idioma_id":4,"titulo":"Determinants and geographical variation in the distribution of depression in the Southern cone of Latin America: A population-based survey in four cities in Argentina, Chile and Uruguay","resumen":"Background Depression is one of the major contributors to the global burden of diseases; however, population-based data in South America are limited. Methods We conducted a population-based cross sectional study with 7524 participants, aged 35?74 years old, recruited between February 2010 and December 2011 from randomly selected samples in 4 cities (Bariloche and Marcos Paz, Argentina; Temuco, Chile; and Pando-Barros Blancos, Uruguay). Major Depressive Episode (MDE) was assessed using the Patient Health Questionnaire (PHQ) ? 9. Results The overall prevalence of MDE was 14.6% (95% CI: 13.6, 15.6). However, there was a geographical variability of up to 3.7 folds between different cities being 5.6% (95% CI: 4.6, 6.7) in Marcos Paz, Argentina; 9.5% (95% CI: 8.2, 10.9) in Bariloche, Argentina; 18.1% (95% CI: 16.3, 20.0) in Temuco, Chile, and 18.2 (95% CI: 16.3, 20.2) in Pando-Barros Blancos, Uruguay. The multivariate model showed that, adjusted by location, being female, being between 35 and 44 years old, having experienced at least one stressful life event, currently smoking, and having a history of chronic medical diseases were independently associated with an increased risk of MDE, while having higher education and being married or living with a partner reduced the risk of MDE. Limitations These results are representative of the selected cities included in the study. As such extrapolation to the general populations of Argentina, Chile, and Uruguay should be done with caution Conclusions This study showed a high prevalence and variability of MDE in the Southern Cone of Latin America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241830,"idioma_id":4,"titulo":"Educational intervention to improve effectiveness in treatment and control of patients with high cardiovascular risk in low-resource settings in Argentina: Study protocol of a cluster randomised controlled trial","resumen":"Introduction: Hypercholesterolaemia is estimated to cause 2.6 million deaths annually and one-third of the cases of ischaemic heart disease. In Argentina, the prevalence of hypercholesterolaemia increased between 2005 and 2013 from 27.9% to 29.8%. Only one out of four subjects with a self-reported diagnosis of coronary heart disease is taking statins. Since 2014, statins (simvastatin 20 mg) are part of the package of drugs provided free-of-charge for patients according to cardiovascular disease (CVD) risk stratification. The goal of this study is to test whether a complex intervention targeting physicians and pharmacist assistants improves treatment and control of hypercholesterolaemia among patients with moderate-to-high cardiovascular risk in Argentina. Methods and analysis: This is a cluster trial of 350 patients from 10 public primary care centres in Argentina to be randomised to either the intervention or usual care. The study is designed to have 90% statistical power to detect a 0.7 mmol\/L reduction in low-density lipoproteins cholesterol from baseline to 12 months. The physician education programme consists of a 2-day initial intensive training and certification workshop followed by educational outreach visits (EOVs) conducted at 3, 6 and 9 months from the outset of the study. An on-site training to pharmacist assistants during the first EOV is performed at each intervention clinic. In addition, two intervention support tools are used: an app installed in physician´s smartphones to serve as a decision aid to improve prescription of statins according to patient´s CVD risk and a web-based platform tailored to send individualised SMS messages to patients. Ethics and dissemination: Ethical approval was obtained from an independent ethics committee. Results of this study will be presented to the Ministry of Health of Argentina for potential dissemination and scale-up of the intervention programme to the entire national public primary care network in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241832,"idioma_id":4,"titulo":"Collecting evidence to inform salt reduction policies in argentina: Identifying sources of sodium intake in adults from a population-based sample","resumen":"The maximum content of sodium in selected processed foods (PF) in Argentina was limited by a law enacted in 2013. Data about intake of these and other foods are necessary for policy planning, implementation, evaluation, and monitoring. We examined data from the CESCAS I population-based cohort study to assess the main dietary sources among PF and frequency of discretionary salt use by sex, age, and education attainment, before full implementation of the regulations in 2015. We used a validated 34-item FFQ (Food Frequency Questionnaire) to assess PF intake and discretional salt use. Among 2127 adults in two Argentinean cities, aged 35-76 years, mean salt intake from selected PFs was 4.7 g\/day, higher among male and low education subgroups. Categories of foods with regulated maximum limits provided near half of the sodium intake from PFs. Use of salt (always\/often) at the table and during cooking was reported by 9% and 73% of the population, respectively, with higher proportions among young people. Reducing salt consumption to the target of 5 g\/day may require adjustments to the current regulation (reducing targets, including other food categories), as well as reinforcing strategies such as education campaigns, labeling, and voluntary agreement with bakeries.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241833,"idioma_id":4,"titulo":"Effect of a community health worker&ndash;led multicomponent intervention on blood pressure control in low-income patients in Argentina: A randomized clinical trial","resumen":"IMPORTANCE: Despite extensive knowledge of hypertension treatment, the prevalence of uncontrolled hypertension is high and increasing in low- and middle-income countries. OBJECTIVE: To test whether a community health worker&ndash;led multicomponent intervention would improve blood pressure (BP) control among low-income patients with hypertension. DESIGN, SETTING, AND PARTICIPANTS: A cluster randomized trial was conducted in 18 centers for primary health care within a national public system providing free medications and health care to uninsured patients in Argentina. A total of 1432 low-income adult patients with uncontrolled hypertension were recruited between June 2013 and April 2015 and followed up to October 2016. INTERVENTIONS: Nine centers (743 patients) were randomized to the multicomponent intervention, which included a community health worker&ndash;led home intervention (health coaching, home BP monitoring, and BP audit and feedback), a physician intervention, and a text-messaging intervention over 18 months. Nine centers (689 patients) were randomized to usual care. MAIN OUTCOMES AND MEASURES: The coprimary outcomes were the differences in systolic and diastolic BP changes from baseline to the end of follow-up of patients with hypertension. Secondary outcomes included the proportion of patients with controlled hypertension (BP &lt;140\/90 mm Hg). Three BP measurements were obtained at each of 2 baseline and 2 termination visits using a standard protocol, the means of which were used for analyses. RESULTS: &nbsp; &nbsp; &nbsp;Of 1432 participants (mean age, 55.8 years [SD, 13.3]; 772 women [53.0%]), 1357 (94.8%) completed the trial. Baseline mean systolic BP was 151.7 mm Hg for the intervention group and 149.8 mm Hg for the usual care group; the mean diastolic BP was 92.2 mm Hg for the intervention group and 90.1 mm Hg for the usual care group. Systolic BP reduction from baseline to month 18 was 19.3 mm Hg (95% CI, 17.9-20.8 mm Hg) for the intervention group and 12.7 mm Hg (95% CI, 11.3-14.2 mm Hg) for the usual care group; the difference in the reduction was 6.6 mm Hg (95% CI, 4.6-8.6; P &lt; .001). Diastolic BP decreased by 12.2 mm Hg (95% CI, 11.2-13.2 mm Hg) in the intervention group and 6.9 mm Hg (95% CI, 5.9-7.8 mm Hg) in the control group; the difference in the reduction was 5.4 mm Hg (95% CI, 4.0-6.8 mm Hg; P &lt; .001). The proportion of patients with controlled hypertension increased from 17.0% at baseline to 72.9% at 18 months in the intervention group and from 17.6% to 52.2% in the usual care group; the difference in the increase was 20.6% (95% CI, 15.4%-25.9%; P &lt; .001). No adverse events were reported. CONCLUSIONS AND RELEVANCE: Low-income patients in Argentina with uncontrolled hypertension who participated in a community health worker&ndash;led multicomponent intervention experienced a greater decrease in systolic and diastolic BP than did patients who received usual care over 18 months. Further research is needed to assess generalizability and cost-effectiveness of this intervention and to understand which components may have contributed most to the outcome. TRIAL REGISTRATION: &nbsp; &nbsp; &nbsp;clinicaltrials.gov Identifier: NCT01834131.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241835,"idioma_id":4,"titulo":"Associations between dietary patterns and serum lipids, apo and C-reactive protein in an adult population: evidence from a multi-city cohort in South America","resumen":"Several previous epidemiological studies from developed countries have shown that an unhealthy dietary pattern affects plasma lipid levels andinflammation biomarkers. We assessed the cross-sectional associations between dietary patterns and cardiovascular risk factors among 961adults from a multi-city cohort in South America. We conducted a principal component analysis to derive dietary patterns. As outcomes, weexamined plasma levels of apo A-I, apo B, high-sensitivity C-reactive protein (hs-CRP), LDL-, HDL- and serum total cholesterol and TAG. Thecrude and adjusted changes in each outcome were estimated for quartiles of dietary patterns using multivariable linear regression models. Theprudent pattern (PP) characterised by higher intake of fruits, vegetables, fish, seafood, whole cereal and low-fat dairy products was associatedwith reduced plasma concentrations of apo B (&#8722;8·5mg\/l), total cholesterol (&#8722;18·8 mg\/dl) and LDL-cholesterol (&#8722;16·5mg\/dl) and hs-CRP(&#8722;1·6mg\/l) in men. In women also reduced plasma concentrations of apo B (&#8722;6·6mg\/l), total (&#8722;12·0mg\/dl) and LDL (&#8722;9·3mg\/dl). The ?Westernlike?pattern characterised by higher intake of eggs, pastry and cakes, pizza, snacks, refined grains, red meat, vegetable oils and poultry was notsignificantly associated with any of the selected serum lipid or inflammatory biomarkers. The explained variances were 10·3 and 7·4%,respectively. The PP was associated with better lipid profile, mainly lower atherogenic particles (apo B) and LDL-cholesterol and serum totalcholesterol. This study provides possible evidence of a prudent diet in South American populations to help reduce the burden of CVD.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241836,"idioma_id":4,"titulo":"Educational intervention to improve effectiveness in treatment and control of patients with high cardiovascular risk in low-resource settings in Argentina: Study protocol of a cluster randomised controlled trial","resumen":"Introduction: Hypercholesterolaemia is estimated to cause 2.6 million deaths annually and one-third of the cases of ischaemic heart disease. In Argentina, the prevalence of hypercholesterolaemia increased between 2005 and 2013 from 27.9% to 29.8%. Only one out of four subjects with a self-reported diagnosis of coronary heart disease is taking statins. Since 2014, statins (simvastatin 20 mg) are part of the package of drugs provided free-of-charge for patients according to cardiovascular disease (CVD) risk stratification. The goal of this study is to test whether a complex intervention targeting physicians and pharmacist assistants improves treatment and control of hypercholesterolaemia among patients with moderate-to-high cardiovascular risk in Argentina. Methods and analysis: This is a cluster trial of 350 patients from 10 public primary care centres in Argentina to be randomised to either the intervention or usual care. The study is designed to have 90% statistical power to detect a 0.7 mmol\/L reduction in low-density lipoproteins cholesterol from baseline to 12 months. The physician education programme consists of a 2-day initial intensive training and certification workshop followed by educational outreach visits (EOVs) conducted at 3, 6 and 9 months from the outset of the study. An on-site training to pharmacist assistants during the first EOV is performed at each intervention clinic. In addition, two intervention support tools are used: an app installed in physician´s smartphones to serve as a decision aid to improve prescription of statins according to patient´s CVD risk and a web-based platform tailored to send individualised SMS messages to patients. Ethics and dissemination: Ethical approval was obtained from an independent ethics committee. Results of this study will be presented to the Ministry of Health of Argentina for potential dissemination and scale-up of the intervention programme to the entire national public primary care network in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241837,"idioma_id":4,"titulo":"Preventable Ischaemic Heart Disease and Stroke Deaths Attributable to Insufficient Physical Activity: A Comparative Risk Assessment Analysis in the Argentinian Population","resumen":"Background: Physical inactivity is estimated to be the 9thleading risk factor for all-cause mortality in Argentina. However,its impact on specific causes of death has not beenevaluated using nationally representative data.Design: We conducted a comparative risk assessment analysisto estimate the proportion and number of IHD and strokedeaths in Argentina that are attributable to different non-optimallevels of physical activity (PA).Methods: We obtained data on prevalence of different levelsof PA from the Argentinian National Survey of Risk Factorsin 2013 and used relative risks for IHD and stroke mortalityfrom previous meta-analyses. Deaths due to IHD andstroke, by age and sex, were obtained from the nationaldeath registry for the year 2010. We considered 4 categoriesof PA based on the metabolic equivalent tasks per minuteper week (METs.min\/week): inactive, &lt; 600, &#8805; 600 to &lt;1,600 and &#8805; 1,600.Results: In Argentina, 76.8% (CI 95%; 75.8%-77.7%) of thepopulation older than 30-years-old engaged in &lt; 1,600METs.min\/week. This level of insufficient activity contributedto 26% of CVD deaths (IHD or stroke) (11,234 of 43,796deaths; 6,013 in men and 5,221 in women); 29% (7,292) ofIHD deaths; and 21% (3,942) of stroke deaths. The impactof insufficient PA was higher in individuals younger than70-years-old due to stronger associations between non-optimalPA and mortality from IHD and stroke.Conclusions: A non-optimal level of PA contributes substantiallyto the mortality burden of cardiovascular diseases in Argentina,especially in individuals under 70-years-old. More substantialresources should be directed toward enhancing builtand social environments which are essential to effectively increasePA, to improve health-related quality of life and reducethe burden of cardio-metabolic diseases in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241838,"idioma_id":4,"titulo":"Determinants and geographical variation in the distribution of depression in the Southern cone of Latin America: A population-based survey in four cities in Argentina, Chile and Uruguay","resumen":"Background Depression is one of the major contributors to the global burden of diseases; however, population-based data in South America are limited. Methods We conducted a population-based cross sectional study with 7524 participants, aged 35&ndash;74 years old, recruited between February 2010 and December 2011 from randomly selected samples in 4 cities (Bariloche and Marcos Paz, Argentina; Temuco, Chile; and Pando-Barros Blancos, Uruguay). Major Depressive Episode (MDE) was assessed using the Patient Health Questionnaire (PHQ) &ndash; 9. Results The overall prevalence of MDE was 14.6% (95% CI: 13.6, 15.6). However, there was a geographical variability of up to 3.7 folds between different cities being 5.6% (95% CI: 4.6, 6.7) in Marcos Paz, Argentina; 9.5% (95% CI: 8.2, 10.9) in Bariloche, Argentina; 18.1% (95% CI: 16.3, 20.0) in Temuco, Chile, and 18.2 (95% CI: 16.3, 20.2) in Pando-Barros Blancos, Uruguay. The multivariate model showed that, adjusted by location, being female, being between 35 and 44 years old, having experienced at least one stressful life event, currently smoking, and having a history of chronic medical diseases were independently associated with an increased risk of MDE, while having higher education and being married or living with a partner reduced the risk of MDE. Limitations These results are representative of the selected cities included in the study. As such extrapolation to the general populations of Argentina, Chile, and Uruguay should be done with caution Conclusions This study showed a high prevalence and variability of MDE in the Southern Cone of Latin America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241839,"idioma_id":4,"titulo":"Collecting Evidence to Inform Salt Reduction Policies in Argentina: Identifying Sources of Sodium Intake in Adults from a Population-Based Sample","resumen":"The maximum content of sodium in selected processed foods (PF) in Argentina was limited by a law enacted in 2013. Data about intake of these and other foods are necessary for policy planning, implementation, evaluation, and monitoring. We examined data from the CESCAS I population-based cohort study to assess the main dietary sources among PF and frequency of discretionary salt use by sex, age, and education attainment, before full implementation of the regulations in 2015. We used a validated 34-item FFQ (Food Frequency Questionnaire) to assess PF intake and discretional salt use. Among 2127 adults in two Argentinean cities, aged 35?76 years, mean salt intake from selected PFs was 4.7 g\/day, higher among male and low education subgroups. Categories of foods with regulated maximum limits provided near half of the sodium intake from PFs. Use of salt (always\/often) at the table and during cooking was reported by 9% and 73% of the population, respectively, with higher proportions among young people. Reducing salt consumption to the target of 5 g\/day may require adjustments to the current regulation (reducing targets, including other food categories), as well as reinforcing strategies such as education campaigns, labeling, and voluntary agreement with bakeries.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241840,"idioma_id":4,"titulo":"Prevalence, awareness, treatment and control of diabetes and impaired fasting glucose in the Southern Cone of Latin America","resumen":"AbstractAimsTo determine the prevalence, treatment and control of diabetes mellitus (DM) and impaired fasting glucose (IFG) as well as associated factors in the adult population of four cities of the Southern Cone of Latin America (SCLA).MethodsThis is a cross-sectional population-based study that included 7407 adults between 35 and 74 years old in four cities of the SCLA: Temuco (Chile), Marcos Paz and Bariloche (Argentina), and Pando-Barros Blancos (Uruguay). DM was defined as fasting plasma glucose &#8805;126 mg\/dL or self-reported history of diabetes. Awareness, treatment, and control of DM were defined as subjects self-reporting a DM previous diagnosis, the use of a prescription medication or nonpharmacological intervention for DM, and fasting plasma glucose &lt;126 mg\/dl, respectively.ResultsPrevalence of DM varied among cities, between 8.4% in Bariloche and 14.3% in Temuco. Prevalence of IFG varied at different sites, from 3.5% in Barros Blancos to 6.8% in Marcos Paz. Of the total number of people with diabetes, 20% were newly diagnosed at the time of the study. Overall, 79.8% of patients with diabetes were aware of their condition. The treatment and control rate were 58.8% and 46.2%, respectively. Older age, family history of diabetes, lower educational attainment, overweight, obesity, central obesity, low physical activity, hypertension, hypercholesterolemia and hypertriglyceridemia were all significantly associated with an increased risk of diabetes.ConclusionsThe prevalence of DM and IFG in the adult population of the SCLA is high and varies among cities. These conditions represent a public health challenge since the rates of awareness, treatment, and control are still low.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241841,"idioma_id":4,"titulo":"Effect of a Community HealthWorker?Led Multicomponent Intervention on Blood Pressure Control in Low-Income Patients in Argentina. A Randomized Clinical Trial","resumen":"Importance&nbsp;    Despite extensive knowledge of hypertension treatment, the prevalence of uncontrolled hypertension is high and increasing in low- and middle-income countries.Objective&nbsp;    To test whether a community health worker?led multicomponent intervention would improve blood pressure (BP) control among low-income patients with hypertension.Design, Setting, and Participants&nbsp;    A cluster randomized trial was conducted in 18 centers for primary health care within a national public system providing free medications and health care to uninsured patients in Argentina. A total of 1432 low-income adult patients with uncontrolled hypertension were recruited between June 2013 and April 2015 and followed up to October 2016.Interventions&nbsp;    Nine centers (743 patients) were randomized to the multicomponent intervention, which included a community health worker?led home intervention (health coaching, home BP monitoring, and BP audit and feedback), a physician intervention, and a text-messaging intervention over 18 months. Nine centers (689 patients) were randomized to usual care. Main Outcomes and Measures&nbsp;    The coprimary outcomes were the differences in systolic and diastolic BP changes from baseline to the end of follow-up of patients with hypertension. Secondary outcomes included the proportion of patients with controlled hypertension (BP &lt;140\/90 mm Hg). Three BP measurements were obtained at each of 2 baseline and 2 termination visits using a standard protocol,  the means of which were used for analyses.Results&nbsp;    Of 1432 participants (mean age, 55.8 years [SD, 13.3]; 772 women [53.0%]), 1357 (94.8%) completed the trial. Baseline mean systolic BP was 151.7 mm Hg for the intervention group and 149.8 mm Hg for the usual care group; the mean diastolic BP was 92.2 mm Hg for the intervention group and 90.1 mm Hg for the usual care group. Systolic BP reduction from baseline to month 18 was 19.3 mm Hg (95% CI, 17.9-20.8 mm Hg) for the intervention group and 12.7 mm Hg (95% CI, 11.3-14.2 mm Hg) for the usual care group; the difference in the reduction was 6.6 mm Hg (95% CI, 4.6-8.6; P&#8201;&lt;&#8201;.001). Diastolic BP decreased by 12.2 mm Hg (95% CI, 11.2-13.2 mm Hg) in the intervention group and 6.9 mm Hg (95% CI, 5.9-7.8 mm Hg) in the control group; the difference in the reduction was 5.4 mm Hg (95% CI, 4.0-6.8 mm Hg; P&#8201;&lt;&#8201;.001). The proportion of patients with controlled hypertension increased from 17.0% at baseline to 72.9% at 18 months in the intervention group and from 17.6% to 52.2% in the usual care group; the difference in the increase was 20.6% (95% CI, 15.4%-25.9%; P&#8201;&lt;&#8201;.001). No adverse events were reported.Conclusions and Relevance&nbsp;    Low-income patients in Argentina with uncontrolled hypertension who participated in a community health worker?led multicomponent intervention experienced a greater decrease in systolic and diastolic BP than did patients who received usual care over 18 months. Further research is needed to assess generalizability and cost-effectiveness of this intervention and to understand which components may have contributed most to the outcome.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241842,"idioma_id":4,"titulo":"DATASET OF THE TRANSCRIBED 45S RIBOSOMAL RNA SEQUENCE OF THE TREE CROP YERBA MATE","resumen":"This contribution contains data related to the research article entitled The 18S-25S ribosomal RNA unit of yerba mate (Ilex paraguariensis A. St.-Hil.) (Aguilera et al., 2016). Through a bioinformatic approach involving NGS data, we provide information of the transcribed 45S ribosomal RNA (rRNA) sequence of yerba mate, the first reference for the Ilex L. genus. This dataset comprises information regarding the assembly and annotation of this rRNA unit. The generated data is applicable for comparative analysis and evolutionary studies among Ilex and related taxa. The raw sequencing data used here is available at DDBJ\/EMBL\/GenBank (NCBI Resource Coordinators, 2016) Sequence Read Archive (SRA) under the accession SRP043293 and the consensus 45S ribosomal RNA sequence has been deposited there under the accession GFHV00000000.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241843,"idioma_id":4,"titulo":"AN INTEGRATED PHYSICAL MAP OF THE CULTIVATED HOT CHILI PEPPER CAPSICUM BACCATUM VAR. PENDULUM","resumen":"Capsicum baccatum var. Pendulum is the most frequently cultivated chili pepper in South America. This taxon is an outstanding source for breeding programs and genetic improvement in the genus, since its traits can be introgressed into C. annuum and related species to generate viable hybrids. In this study, the chromosome complement of C. baccatum var. Pendulum 2n = 24 was deeply characterized through a sequential combination of conventional and molecular cytogenetics approaches comprising Ag-NOR staining, heterochromatic fluorescence C-DAPI and CMA\/DA\/DAPI bandings and fluorescent in situ hybridization (FISH) of Capsicum-derived 5S and 18S-25S ribosomal genes and spacers probes. The attained markers were systematically integrated into a physical map which allows the identification of each individual chromosome. This is the first integrated physical map of C. baccatum var. Pendulum, which in conjunction with reported genetic linkage maps of Capsicum, would be useful for future high-density genetic mapping and whole-genome studies in C. baccatum and related taxa, as well as in breeding and genetic improvement programs in chili peppers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241845,"idioma_id":4,"titulo":"INFLAMATION, OXIDATIVE STRESS AND GENE EXPRESSION IN PATIENTS WITH CHAGASIC CARDIOMYOPATHY.","resumen":"Background: The pathogenesis of chronic chagasic cardiomyopathy (CCM) is controversial, there are no definitive proofs of which are the necessary factors to reach the determinate stage. Each host genetic factors could actively participate in the evolution of Chagas disease. Whereas the variability of phenotypic expression of the CCM could be because of genetic components of the patient, we decided to do a descriptive study of genotype frequencies (GF) of SOD-Mn Ala-9-Val, the enzyme activities of superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT), and as marker of inflammation factor tumor necrosis (TNFalpha) in chagasic patients with cardiomyopathy (G1) and without cardiomyopathy (G2) compared with healthy controls (CN). Methods: The molecular characterization was performed by PCR-RFLP. Enzyme activities were determined by spectrophotometric techniques and the tumor necrosis factor alpha (TNFalpha) by immuno method (ELISA - BD OptEIA TNF HU). The hypothesis test under normal theory proportions and Kruskal Wallis test were carried out. Results: The SOD-Mn FG (IC 95%) were CN: Ala\/Ala 0.54 (0.40-0.67), Ala\/Val 0.33 (0.20-0.45), Val\/Val 0.13 (0.04-0.21); G2: Ala\/Ala 0.36 (0.07-0.64), Ala\/Val 0.46 (0.16-0.75), Val\/Val 0.18 (0.00-0.40); G1: Ala\/Ala 0.35 (0.14-0.56), Ala\/Val 0.30 (0.10 - 0.50), Val\/Val 0.35 (0.14 - 0.56). The enzime activities were: CAT(K\/gHb): CN 185±28, G2 332±41, G1 316±68; GPx(U\/gHb): CN  61±11, G2 102±20, G1 98±17; SOD(USOD\/gHb): CN 895±314, G2 2590±188, G1 3270±833. The results TNFalpha(pg\/ml) were CN 7.7±2.4, G2  26.1±6.8, G1 33.3±7.2. The study of SOD-Mn GF of chagasic patients and CN showed significant differences (p <0.01) between them. The activities of CAT, SOD, GPx and TNFalpha showed significant differences (p <0.01) between chagasic patients and CN. Conclusions: The data suggest that polymorphisms and inflamation involved in oxidative stress may have implications in the pathogenesis of CCM, modifying individual risk in the development of cardiomyopathies. These biomarkers are potentially useful in the design of predictive models to identify chagasic patients at risk of developing clinical complications.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241850,"idioma_id":4,"titulo":"Industrial Plant at Academic Level for Teaching Industrial Informatics in an Electronic Engineering Undergraduate Degree","resumen":"This paper presents the design of an academic level simulation for an industrial plant and the current status of practice activities proposed for an undergraduate course on Industrial Automation for Electronic Engineering students. Strongly focalized in professional processes and methods, in particular, it deals with the specific activities developed by electronic engineers at the lower lever of the automation pyramid.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241869,"idioma_id":4,"titulo":"Fungal Biodiversity Profiles 21-30","resumen":"Abstract: The authors describe ten new taxa for science using mostly both morphological and molecular data. In Basidiomycota, descriptions are provided for Botryobasidium fusisporum sp. nov., B. triangulosporum sp. nov., Cantharellus hydnoides sp. nov. and Hydnum aerostatisporum sp. nov. in Cantharellales; Lactarius rahjamalensis sp. nov. and Russula pseudoaurantiophylla sp. nov. in Russulales and for Mycena paraguayensis comb.nov. in Agaricales. In Ascomycota and hyphomycetes, descriptions are provided for Colletotrichum eryngiicola sp. nov. (Glomerellales), Corynesporella indica sp. nov. (incertae sedis) and Repetophragma zygopetali sp. nov. (Microthyriales).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241870,"idioma_id":4,"titulo":"First record of Macrocybe titans (Tricholomataceae - Basidiomycota) in Argentina","resumen":"Abstract: Macrocybe titans is characterized by its basidiomata with a remarkable size, the squamose stipe surface, and the pseudocystidia with refractive content. In this paper, we describe and analyze the macro and microscopic features of Argentinian collections of this species, and provide photographs of its basidiomata and drawings of the most relevant microscopic structures. In addition, we present a map with the American distribution of M. titans, highlighting the first record of this species for the country.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241871,"idioma_id":4,"titulo":"Phylogenetic analyses support the recent placement of Canoparmelia scrobicularis into Crespoa (Parmeliaceae, lichenized Ascomycota)","resumen":"Abstract: A phylogenetic study based on the formal barcoding marker for fungi (ITS) was carried out within the Parmotrema clade to evaluate the recent combination of Canoparmelia scrobicularis into Crespoa, and to assess the monophyly of the genus Crespoa. Twenty-six sequences were newly generated, which were analyzed together with 14 retrieved from GenBank, representing a total 25 species of the genera Austroparmelina (5), Canoparmelia (4), Crespoa (5), and Parmotrema (11). The sequences were aligned and analyzed by MP, ML, and BI methods. Our results have shown that Crespoa scrobicularis clearly constitutes a monophyletic group together with the other known Crespoa species, supporting its recent placement within Crespoa and the monophyly of the genus as currently defined.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241872,"idioma_id":4,"titulo":"Range extension of Relicina subabstrusa (Parmeliaceae, lichenized Ascomycota) in Argentina and its distribution pattern in the Neotropics","resumen":"Relicina subabstrusa is known from a few scattered records in the Neotropics. This species lacks any propagules and has a black lower surface and coronate apothecia. This paper extends the known distributional range of R. subabstrusa in Argentina and maps its geographic distribution in the Neotropics. Notes on similar taxa and an updated key for the identification of the Neotropical species of the genus are provided.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241873,"idioma_id":4,"titulo":"New Species of the Heterodermia comosa-Group (Physciaceae, Lichenized Ascomycota) from Southern South America","resumen":"A revision of the specimens from southern South America deposited at CTES herbarium identified as Heterodermia comosa (Eschw.) Follmann & Redón was made. As a result, four new species, viz. H. mobergiana Michlig, M.P. Rodríguez & Aptroot, H. neocomosa M.P. Rodríguez L.I. Ferraro & Aptroot, H. ramosociliata M.P. Rodríguez, Michlig & Aptroot, and H. sorediosa Michlig, L.I. Ferraro & Aptroot, all closely related to H. comosa, are here proposed. Each species is described, illustrated and commented. A distribution map is also presented.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241885,"idioma_id":5,"titulo":"Una técnica de las ciencias sociales: escritura y auto observación en la investigación en artes.","resumen":"¿Cuáles son los sentidos de la investigación cuando es artística? ¿Cómo resolver la narración de la producción? ¿Es narrable el proceso creativo? ¿Qué significa textualizar? ¿Podrían las metodologías de investigación de las ciencias sociales aportar y vincularse con la textualidad del proceso? Con que técnica específica podría resolverse esta narración? En la creación artística, la función de la escritura (memoria reflexiva) es considerada un instrumento central para la toma de distancia y contemplación, a la vez que la observancia del estilo posibilita leer el resonar de la obra, como una reconstrucción desde palabras de un proceso que es el de la creación misma. La reelaboración del proceso a través de su escritura, constituye un esfuerzo consciente y guiado a la manera de una auto observación que completa el sentido de un recorrido y presenta otra especificidad en el aporte final del trabajo.La siguiente reflexión busca establecer un vínculo teórico entre las características de la técnica de la auto observación y la explicitación del proceso creativo a través de la escritura en la investigación en artes. Para ello retomamos una experiencia particular de formación en investigación de un Ciclo de Articulación en una Carrera de Artes de una facultad pública, donde el trabajo final incluye la posibilidad de una producción artística conjunta con una narración del proceso creativo. Consideramos que los matices de la auto observación como técnica, aportan a la escritura en artes (textualidad del proceso creativo) y dotan de una dimensión resonante socialmente, a las obras y al trabajo de quienes las producen.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241886,"idioma_id":4,"titulo":"Effects of Temperature and Thiourea Addition on the Electrodeposition of Tin on Glassy Carbon Electrodes in Acid Solutions","resumen":"The electrodeposition of tin on glassy carbon electrodes was studied in plain and thiourea-containing sulphuric acid solutions at different temperatures. Voltammograms exhibit a single cathodic current peak related to the electroreduction of tin ions on the glassy carbon substrate. The current of this peak increases linearly with the square root of the scan rate in the absence of thiourea, as expected for an electrochemical reaction under diffusion control. However, with the addition of thiourea, the peak current exhibits a semi-logarithmic dependence. Electrodeposition current transients show always a single peak that increases its height and appears at shorter times as the electrode potential is made more negative. The non-dimensional analysis of the current transients suggests the occurrence of an instantaneous nucleation and 3D growth under diffusion control in thiourea-free solutions. When thiourea is added, the transient current peak shifts to longer times and the non-dimensional analysis agrees with the presence of a progressive nucleation process. Seemingly, thiourea adsorbs on the electrode surface blocking active sites. This is consistent with the changes observed in the morphology of tin deposits, which change from well-distributed small crystallographic particles in the absence of thiourea, to complex and larger ones that exhibit branches at 900, in the presence of thiourea. Nyquist plots exhibit only two time constants at open circuit conditions, while in the potential range of tin electrodeposition two capacitive contributions appear at high an medium frequencies, followed by an inductance, assigned to a surface relaxation process, and a Warburg contribution, associated with the transport of ions to the interface, at low frequencies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241889,"idioma_id":5,"titulo":"Otros-Nos. Algunas reflexiones (sobre) lenguaraces y cautivas más allá de las dualidades identitarias","resumen":"Este trabajo recorre algunas obras narrativas y visuales producidas durante la formación del Estado Nación argentino a fin de reflexionar en torno de las fronterizas figuras de cautivas y lenguaraces. Con ello se busca poner en tensión las imágenes maniqueas y binarias sobre la identidad nacional que fueran afirmadas por la lógica estatal en tiempos de la llamada Conquista del Desierto. Tal abordaje se propone entonces políticamente significativo en tanto no solo invita a discutir y pensar más allá de las segmentarizaciones socioculturales hegemónicas (rígidas, biunívocas, centralistas y substancializantes) sino que también interpela, en pasado y presente, a aquellas capturadas, invisibilizadas y silenciadas por la lógica del Estado Nación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241892,"idioma_id":4,"titulo":"Bureaucratic Circuits of Repression: The Role of the Judicial Morgue in Argentina?s State Terrorism (1976-1983)","resumen":"Durante la última dictadura en la Argentina (1976-1983), la Morgue Judicial de la Ciudad de Buenos Aires fue utilizada por fuerzas militares como uno de los circuitos posibles para deshacerse de los cuerpos de los detenidos-desaparecidos. A partir del análisis de la causa judicial presentada en 1982 por el Centro de Estudios Legales y Sociales(CELS) conocida como la Causa de la Morgue Judicial, este artículo indagará tanto sobre el tratamiento que tuvieron los cadáveres de detenidos-desaparecidos que ingresaron irregularmente a la Morgue, como sobre las lógicas y prácticas de los médicos y empleados que intervinieron en este proceso. Finalmente, se buscará reflexionar sobre las huellas dejadas por las burocracias judiciales y administrativas con respecto a los crímenes cometidos por la dictadura y sobre las estrategias jurídicas desplegadas por abogados y familiares de las víctimas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241893,"idioma_id":5,"titulo":"Investigaciones judiciales, investigaciones antropológicas. De cómo el oficio antropológico interviene en la reconstrucción de casos","resumen":"A partir del análisis del caso de una joven cuyos familiares fueron asesinados por efectivos de las Fuerzas Armadas en el año 1977 en la Ciudad de Buenos Aires, el objetivo de este artículo es reflexionar sobre la intervención adoptada por diversas burocracias estatales en los crímenes cometidos por la dictadura  así como sobre el rol desplegado ?en distintos momentos históricos y políticos- por el derecho y las ciencias sociales para la reconstrucción de estas historias. En este sentido, se busca reflexionar, por un lado, sobre la heterogeneidad del Estado aún en circunstancias en las que el poder parecía blindado y concentrado ? el Estado terrorista de la dictadura ? y por el otro, sobre el modo en que el activismo de los Derechos Humanos, las trayectorias personales y el oficio del antropólogo pueden reconstruir historias que el poder terrorista ocultó y tergiversó.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241897,"idioma_id":5,"titulo":"Examinando a la industria maderera de Santiago del Estero. Casos de estudio: Capital, Banda y Loreto","resumen":"Los resultados indicaron que son todas industrias de larga trayectoria que trabajan con muy pocos empleados, los cuales están medianamente capacitados en el oficio.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241903,"idioma_id":4,"titulo":"Vitamin D levels and their impact on mineral metabolism  in HIV infected patients: an exploratory study","resumen":"Vitamin D has immunomodulating properties. The nuclearreceptor for vitamin D is expressed in several immunecells, which convert 25-hydroxyvitamin D(25OHD)to the active form 1,25 hydroxyvitamin D (1,25(OH)2 D).Under conditions of infection, 1,25(OH)2 D promotes productionof cathelicidin (an antimicrobial peptide) inmonocytes and activated macrophages. In vitro studieshave shown the ability of cathelicidin to inhibit replicationof human immunodeficiency virus (HIV-1) in T CD4lymphocytes and macrophages. Objective. To evaluatevitamin D levels and their impact on mineral metabolismin HIV infected patients. Materials and methods. Seventy-fourclinical records of HIV\/AIDS patients seen at theoutpatients clinic were reviewed. The following datawere collected: age, sex, time since diagnosis of HIV,HIV-1 viral load, CD4 counts (absolute value and percentage),and mineral metabolism determinations:25OHD, intact parathormone (iPTH); serum calcium(sCa); serum phosphorus (sP) and serum crosslaps (sCTX).Vitamin D levels were stratified as follows: optimal:&#8805;30ng\/ml; insufficient: 21-29ng\/ml; moderately deficient:20³ -25OHD- >10 ng\/ml and severely deficient &#8804;10 ng\/ml.Results. Fifty-five clinical records were included; 82% ofpatients had 25OHD levels below 30ng\/ml (insufficient:23.6%, moderately deficient: 36.4%; and severely deficient:21.8%). A significantly higher serum PTH levels in the moderately and severely deficient groups than in theoptimal and insufficient groups was observed (p<0.05and p<0.03 respectively). A weak negative correlationwas observed between serum 25OHD and PTH levels (r=-0.268; p<0.004). Conclusion. Sub-optimal vitamin D levelsare frequently observed in HIV\/AIDS patients on antiretroviraltherapy (ART). Systematic assessment of mineralmetabolism is considered necessary in HIV\/AIDSpositive patients.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241904,"idioma_id":5,"titulo":"En búsqueda de estímulos para el aprendizaje: la utilización de producciones audiovisuales en la enseñanza de contenidos hitórico-culturales en el Profesorado de Lengua Inglesa","resumen":"Esta propuesta está basada en una investigación exploratoria descriptiva en curso denominada ?La utilización de producciones audiovisuales en el aprendizaje de contenidos histórico-culturales a nivel universitario: una propuesta didáctica para el Profesorado en Lengua Inglesa? de la Universidad Nacional de Villa María, cuyo objetivo principal es enriquecer el aprendizaje de los contenidos histórico-culturales del espacio curricular Perspectivas del Mundo Actual del mencionado profesorado. En el marco de este proyecto nos encontramos diseñando material de apoyo adicional y extra áulico que resulte motivador, atractivo y esclarecedor. Como es bien sabido, en los últimos años las nuevas tecnologías ofrecen a los más jóvenes nuevas formas de incorporar conocimiento que suelen resultar más motivadoras que la metodología tradicional basada exclusivamente en la utilización de textos; en este sentido, el cine sirve de gran incentivo. Asimismo, teniendo en cuenta que las producciones audiovisuales resultan de la unión del reflejo y de la (re)creación de los acontecimientos históricos, es menester indagar, cuestionar y analizar dicha representación visual; por este motivo, el material tendrá el valor agregado de promover las habilidades de pensamiento crítico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241905,"idioma_id":5,"titulo":"La construcción discursiva de las adicciones","resumen":"Se indaga el fenómeno de las adicciones, a partir del análisis arqueológico de la materialidad discursiva que constituye la prensa escrita argentina. Además de una llamativa proliferación de diferentes formas de adicción, que exceden el abuso de sustancias, se observan cuatro rasgos que caracterizan el fenómeno: su individualización y suposición de una causa patológica, la confesión como acceso a los procesos de atención; la necesidad de campañas de prevención y de abordajes particulares; y la subjetivación y pedagogización respecto de los modos de vivir. El discurso médico -legitimado en un ideal moralizador de salud y en la pretensión de cientificidad de su saber-, junto al discurso jurídico y el discurso pedagógico, objetivan este fenómeno como un grave problema que exige una intervención gubernamental ?tanto en lo individual como en lo poblacional- para regular su incidencia. Sin embargo, se excluye la pregunta por las condiciones de posibilidad económicas, sociales, históricas, culturales y políticas, que permiten que un modo particular de subjetividad sea producido, a partir del cual sería potencialmente posible volverse adicto a cualquier cosa. La hipótesis es entonces que este fenómeno es más una línea de fuga frente a la gubernamentalidad actual, que una patología individual, biológica y aleatoria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241906,"idioma_id":5,"titulo":"Confesar la adicción: saber, poder y subjetivación en la prensa escrita argentina (2010-2017)","resumen":"Este trabajo pertenece a la investigación Biopolíticas y Actualidad. Producción discursiva en la prensa escrita argentina (Directora: Dra. Elsa Emmanuele). Se realiza un análisis arqueológico en más de trescientos artículos de la prensa escrita argentina, respecto del fenómeno de las adicciones y las tecnologías de poder vinculada a éste. Se encuentra una incitación dirigida a los\/as usuarios\/as de distintas drogas, a quienes realizan determinadas actividades, y\/o a quienes sostienen ciertos consumos, para que confiesen su condición de adictos\/as. Se mantiene por tanto vigente la técnica de la confesión -un decir veraz sobre algo propio-, perteneciente a las tecnologías de poder dirigidas al sí mismo. Todavía vinculada al discurso jurídico y al poder psiquiátrico, ahora, además, se entrecruza con los medios de comunicación y la opinión de la población. Para finalizar, se muestran posibles salidas a la moralización, pedagogización, criminalización y patologización, basadas en la exploración de elecciones de vida que no reproduzcan esta forma de tecnología de poder, estilos de vida sustentados en la posibilidad de experimentar ética, estética y, por ende, políticamente, formas de consumo y de realizar actividades, que, al menos, ofrezcan un punto de resistencia a la actual incitación a la confesión.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241909,"idioma_id":5,"titulo":"ACTUALIZACIÓN DEL PERFIL PROFESIONAL DEL INGENIERO INDUSTRIAL","resumen":"La formación de los ingenieros es una preocupación constante para los docentes puesto que además de la adquisición de las competencias básicas tales como el trabajo en equipo y la correcta comunicación oral y escrita, los nuevos ingenieros industriales deben tener una sólida formación tanto en ciencia básica como aplicada como conocimientos empíricos para poder desarrollar la capacidad de resolver problemas a partir del diseño de soluciones tecnológicas con las restricciones que el entorno pone. En un mundo donde casi nada está en estado natural, los diseños tecnológicos son los desafíos que encuentra el futuro profesional. El desafío del control de las situaciones, cuya esencia es la comparación de la información sobre lo que está sucediendo y lo que se desea que suceda, produciendo la posibilidad de aplicar correcciones sobre él proceso, para que lo deseado efectivamente suceda Podemos afirmar, que el hombre creo intencionadamente un mundo artificial, es decir cosas artificiales a partir del diseño de las mismas, empleando los conocimientos existentes o los que crea, expresamente para ese fin, mediante la investigación y el desarrollo tecnológico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241911,"idioma_id":4,"titulo":"A structural appraisal of Sterol Carrier Protein 2","resumen":"Sterol Carrier Protein 2 (SCP2) has been associated with lipid binding and transfer activities. However, genomic, proteomic, and structural studies revealed that it is an ubiquitous domain of complex proteins with a variety functions in all forms of life. High-resolution structures of representative SCP2 domains are available, encouraging a comprehensive review of the structural basis for its success. Most SCP2 domains pertain to three major families and are frequently found as stand-alone or at the C-termini of lipid related peroxisomal enzymes, acetyltransferases causing bacterial resistance, and bacterial environmentally important sulfatases. We (1) analyzed the structural basis of the fold and the classification of SCP2 domains; (2) identified structure-determined sequence features; (3) compared the lipid binding cavity of SCP2 and other lipid binding proteins; (4) surveyed proposed mechanisms of SCP2 mediated lipid transfer between membranes; and (5) uncovered a possible new function of the SCP2 domain as a protein-protein recognition device.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241917,"idioma_id":4,"titulo":"Kinetic study of the ethyl lactate synthesis from triose sugars on Sn\/Al2O3 catalysts","resumen":"The reaction kinetics of the liquid-phase synthesis of ethyl lactate from dihydroxyacetone and ethanol was studied on Sn-promoted alumina catalysts. Yields of &#61627;70% were obtained at 353K after 7 hours of reaction. The effect of the catalyst Sn loading (1-8 wt.%) and reaction temperature (343-373K) on the reaction kinetics was investigated. The reaction is promoted by Lewis acid sites provided by surface Sn species. A kinetic model based on a pseudohomogeneous mechanism was postulated to describe the reaction network comprising a sequence of consecutive and parallel reaction steps. The kinetic rate constant associated to ethyl lactate formation increases with the number of Lewis acid sites confirming that surface Sn species participate in the kinetically relevant reaction steps. Catalysts were prepared by impregnation and characterized by N2 physisorption, X-ray diffraction, UV-vis-DRS, FTIR of pyridine and TPD of NH3..","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241920,"idioma_id":4,"titulo":"Ecotoxicity of veterinary enrofloxacin and ciprofloxacin antibiotics on anuran amphibian larvae","resumen":"The ecological risks posed by two &beta;-diketone antibiotics (DKAs, enrofloxacin, ENR and ciprofloxacin, CPX), characterized by their long persistence in aqueous environments and known deleterious effect on model organisms such as zebrafish were analysed using Rhinella arenarum larvae. Sublethal tests were conducted using environmentally relevant concentrations of both ENR and CPX (1&ndash;1000&nbsp;&mu;g&nbsp;L&minus;1) under standard laboratory conditions for 96&nbsp;h. Biological endpoints and biomarkers evaluated were body size, shape, development and growth rates, and antioxidant enzymes (glutathione-S-transferase, GST; Catalase, CAT). Risk assessment was analysed based on ration quotients (RQ). The size and shape measurements of the larvae exposed to concentrations greater than 10&nbsp;&mu;g&nbsp;L&minus;1 of CPX were lower compared to controls (Dunnett post hoc p&nbsp;&lt;&nbsp;0.05) and presented signs of emaciation. Concentrations of 1000&nbsp;&mu;g&nbsp;L&minus;1of CPX induced GST activity, in contrast with inhibited GST and CAT of larvae exposed to ENR. Risk assessments indicated that concentrations greater than or equal to10&nbsp;&mu;g&nbsp;L&minus;1 of CPX and ENR are ecotoxic for development, growth, detoxifying, and oxidative stress enzymes. It is suggested that additional risk assessments may provide evidence of bioaccumulation of CPX and ENR in tissues or organs of amphibian larvae by mesocosm sediment test conditions. Finally, intestinal microbiome studies should be considered to establish the mechanisms of action of both antibiotics.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241921,"idioma_id":5,"titulo":"MELANOMACRÓFAGOS HEPÁTICOS Y ACTIVIDAD DE LA ENZIMA GLUTATION S-TRANSFERASA EN Leptodactylus chaquensis (ANURA, LEPTODACTYLIDAE) COMO BIOMARCADORES DE ESTRÉS OXIDATIVO POR LA EXPOSICIÓN A CLORPIRIFOS","resumen":"We quantified and compared the hepatic melanomacrophage (MM) and glutathione S-transferase (GST) enzyme activity (two oxidative stress biomarkers) in the liver of Leptodatylus chaquensis adults (Anura, Leptodactylidae) collected in a rice field (CA) in San Javier department, Santa Fe (Argentina), seven days after the application of chlorpyrifos and in a reference site (SR). The histological analysis revealed a significant amount (p = 0.028) and area occupied by MM (p = 0.017) in livers of CA compared to SR. Furthermore, a significant inhibition of GST activity was recorded in the CA frogs compared to the SR (p = 0.030). The histopathological and enzymatic effects provide evidences of ecotoxicological risk for anurans in rice field with CPF application.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241922,"idioma_id":4,"titulo":"Altered development, oxidative stress and DNA damage in Leptodactylus chaquensis (Anura: Leptodactylidae) larvae exposed to poultry litter","resumen":"Poultry litter (PL), which is usually used as organic fertilizer, is a source of nutrients, metals, veterinarypharmaceuticals and bacterial pathogens, which, through runoff, may end up in the nearest aquatic ecosystems.In this study, Leptodactylus chaquensis at different development stages (eggs, larval stages 28 and 31 here referredto as stages I, II and III respectively) were exposed to PL test sediments as follows: 6.25% (T1), 12.5% (T2); 25%(T3); 50% (T4); 75% (T5); 100% PL (T6) and to dechlorinated water as control. Larval survival, developmentendpoints (growth rate -GR-, development rate -DR-, abnormalities), antioxidant enzyme activities (Catalase-CAT- and Glutathione-S-Transferase -GST-), and genotoxic effect (DNA damage index by the Comet assay) wereanalyzed at different times. In stage I, no egg eclosion was observed in treatments T3-T6, and 50% of embryomortality was recorded after 24 h of exposure to T2. In stages II and III, mortality in treatments T3-T6 reached100% between 24 and 48 h. In the three development stages evaluated, the DR and GR were higher in controlsthan in PL treatments (T1, T2), except for those T1-treated larvae of stage II. Larvae of stage I showed five typesof morphological abnormalities, being diamond body shape and lateral displacement of the intestine the mostprevalent in T1, whereas larvae of stages II and III presented lower prevalence of abnormalities. In stage I, CATactivity was similar to that of control (p>0.05), whereas it was higher in T1- and T2- treated larvae of stages IIand III than controls (p0.05),whereas it was inhibited in T1-treated larvae of stage II (p<0.05). T1- and T2-treated larvae of stages II and IIIcaused higher DNA damage respect to controls (p<0.05), varying from medium to severe damage (comet typesII, III and IV). These results showed that PL treatments altered development and growth and induced oxidativestress and DNA damage, resulting ecotoxic for L. chaquensis larvae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241923,"idioma_id":4,"titulo":"A comprehensive analysis of direct and photosensitized attenuation of Toxoplasma gondii tachyzoites","resumen":"In the present work, we have evaluated the effect of three different types of radiation: UVC (254 &plusmn; 5 nm), UVA (365 &plusmn; 20 nm) and visible (420 &plusmn; 20 nm) on different morphological and biological functions of Toxoplasma gondii tachyzoites. Briefly, UVC and UVA showed an inhibitory effect on parasite invasion in a dose-dependent manner. UVC showed the strongest effect inducing both structural damage (antigens) and functional inhibition (i.e., invasion and replication). On its own, visible light induces a quite distinctive and selective pattern of parasite-attenuation. This type of incident radiation inhibits the replication of the parasite affecting neither the capability of invasion\/attachment nor the native structure of proteins (antigens) on parasites. Such effects are a consequence of photosensitized processes where phenol red might act as the active photosensitizer. The potential uses of the methodologies investigated herein are discussed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241933,"idioma_id":5,"titulo":"MARCADORES DE FORMACIÓN Y RESORCIÓN ÓSEA Y SU UTILIDAD PARA DETERMINAR EL FINAL DEL PERÍODO DE APOSICIÓN ÓSEA","resumen":"ResumenEl pico de masa ósea (PMO) se alcanzaentre los 20 y 35 años, pero la aposición óseacontinúa hasta alcanzar el pico de fortalezaósea (PFO). Se crea así una ventana entre ambospicos que podría ser evaluada mediantemarcadores bioquímicos de recambio óseo,ya que durante dicho período la densidad mineralpermanece constante. El objetivo fuedeterminar el final de la aposición ósea mediantemarcadores bioquímicos óseos. Seevaluaron por décadas entre 20 y 49 años deedad 139 sujetos sanos de ambos sexos (69hombres y 70 mujeres), determinando fosfatasaalcalina ósea (FAO), osteocalcina (OC),propéptido amino terminal del colágeno tipo1 (P1NP) y telopéptido C-terminal del colágenotipo 1 (CTX). Los marcadores correlacionannegativamente con la edad (OC: r= -0,3;p<0,01; P1NP: r= -0,4; p< 0,01 y CTX: r= -0,4;p< 0,01), exceptuando FAO. En hombres de20-29 años, P1NP y el CTX fueron significativamentemayores vs. 30-39 años (p<0,05 yp<0,001, respectivamente), y entre 30-39 añosvs. de 40-49 años en P1NP y CTX (p<0,05p<0,001, respectivamente). En mujeres de20-29 años, P1NP y CTX fueron significativamentemayores vs. 30-39 años (p<0,0001y p<0,01, respectivamente). Conclusión: losmarcadores de remodelado óseo más sensiblesy específicos permitirían determinar bioquímicamenteel fin de la aposición ósea quese produce entre el PMO y el PFO. Si bien esnecesario ampliar el número de sujetos evaluados,los datos que surgen de la presenteinvestigación sentarían las bases para futurosestudios epidemiológicos referidos al fin de laaposición ósea.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241934,"idioma_id":4,"titulo":"Vitamin D levels and their impact on mineral metabolism  in HIV infected patients: an exploratory study","resumen":"Vitamin D has immunomodulating properties. The nuclearreceptor for vitamin D is expressed in several immunecells, which convert 25-hydroxyvitamin D(25OHD)to the active form 1,25 hydroxyvitamin D (1,25(OH)2 D).Under conditions of infection, 1,25(OH)2 D promotes productionof cathelicidin (an antimicrobial peptide) inmonocytes and activated macrophages. In vitro studieshave shown the ability of cathelicidin to inhibit replicationof human immunodeficiency virus (HIV-1) in T CD4lymphocytes and macrophages. Objective. To evaluatevitamin D levels and their impact on mineral metabolismin HIV infected patients. Materials and methods. Seventy-fourclinical records of HIV\/AIDS patients seen at theoutpatients clinic were reviewed. The following datawere collected: age, sex, time since diagnosis of HIV,HIV-1 viral load, CD4 counts (absolute value and percentage),and mineral metabolism determinations:25OHD, intact parathormone (iPTH); serum calcium(sCa); serum phosphorus (sP) and serum crosslaps (sCTX).Vitamin D levels were stratified as follows: optimal:&#8805;30ng\/ml; insufficient: 21-29ng\/ml; moderately deficient:20³ -25OHD- >10 ng\/ml and severely deficient &#8804;10 ng\/ml.Results. Fifty-five clinical records were included; 82% ofpatients had 25OHD levels below 30ng\/ml (insufficient:23.6%, moderately deficient: 36.4%; and severely deficient:21.8%). A significantly higher serum PTH levels in the moderately and severely deficient groups than in theoptimal and insufficient groups was observed (p<0.05and p<0.03 respectively). A weak negative correlationwas observed between serum 25OHD and PTH levels (r=-0.268; p<0.004). Conclusion. Sub-optimal vitamin D levelsare frequently observed in HIV\/AIDS patients on antiretroviraltherapy (ART). Systematic assessment of mineralmetabolism is considered necessary in HIV\/AIDSpositive patients.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241935,"idioma_id":5,"titulo":"EVALUACIÓN DE LA RESPUESTA DENSITOMÉTRICA EN PACIENTES CON OSTEOPOROSIS POSMENOPÁUSICA TRATADAS CON RANELATO DE ESTRONCIO O DENOSUMAB","resumen":"Tanto el ranelato de estroncio (RSr) comoel denosumab (Dmab) son eficaces en el tratamientode la osteoporosis (OP) posmenopáusica(PM). El efecto de cada fármaco porseparado sobre la densidad mineral ósea(DMO) ha sido estudiado recientemente. Conambas drogas se observó, al año de tratamiento,un aumento significativo de la DMOen columna lumbar (CL), cuello femoral (CF)y cadera total (CT). En este trabajo comparamosla respuesta densitométrica al año detratamiento con una y otra droga. Utilizamoslos registros de 425 pacientes PMOP tratadascon Dmab y 441 tratadas con RSr. En cadapaciente analizamos el porcentaje de cambio;se clasificaron como respondedoras aquellasque mostraron un cambio &#8805;3%. Adicionalmentese comparó la respuesta en pacientes no previamente tratadas con bifosfonatos(BF-naïve) en comparación con pacientes quehabían recibido previamente un BF. Al analizarel grupo completo para Dmab, el porcentajede pacientes respondedoras fue de 68,4%en CL, 63,3% en CF y 49,3% en CT. Por otrolado, en el grupo de pacientes tratadas conRSr, el porcentaje de respondedoras (53,8%en CL, 40,0% en CF y 35,6% en CT) fue estadísticamentemenor. Cuando comparamosla respuesta entre las pacientes BF-naïve querecibieron RSr o Dmab, el Dmab indujo mayorrespuesta en CL y CF que el grupo RSr, sindiferencias en CT. Cuando se analizaron lossubgrupos BF-previo, las tratadas con Dmabmostraron mayor respuesta en todas las regiones.Conclusión: en pacientes con OP-PM,el tratamiento con Dmab produjo mayores incrementosdensitométricos que el RSr, siendo el porcentaje de pacientes respondedorasmayor con Dmab que con RSr.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241936,"idioma_id":4,"titulo":"Greater Gains in Spine and Hip Strength for Romosozumab Compared With Teriparatide in Postmenopausal Women With Low Bone Mass","resumen":"Romosozumab is a monoclonal antibody that inhibits sclerostin and has been shown to reduce the risk of fractures within 12 months. In a phase II, randomized, placebo-controlled clinical trial of treatment-naïve postmenopausal women with low bone mass, romosozumab increased bone mineral density (BMD) at the hip and spine by the dual effect of increasing bone formation and decreasing bone resorption. In a substudy of that trial, which included placebo and teriparatide arms, here we investigated whether those observed increases in BMD also resulted in improvements in estimated strength, as assessed by finite element analysis. Participants received blinded romosozumab s.c. (210 mg monthly) or placebo, or open-label teriparatide (20 &#956;g daily) for 12 months. CT scans, obtained at the lumbar spine (n = 82) and proximal femur (n = 46) at baseline and month 12, were analyzed with finite element software (VirtuOst, O.N. Diagnostics) to estimate strength for a simulated compression overload for the spine (L1 vertebral body) and a sideways fall for the proximal femur, all blinded to treatment assignment. We found that, at month 12, vertebral strength increased more for romosozumab compared with both teriparatide (27.3% versus 18.5%; p = 0.005) and placebo (27.3% versus ?3.9%; p < 0.0001); changes in femoral strength for romosozumab showed similar but smaller changes, increasing more with romosozumab versus teriparatide (3.6% versus ?0.7%; p = 0.027), and trending higher versus placebo (3.6% versus &#8722;0.1%; p = 0.059). Compartmental analysis revealed that the bone-strengthening effects for romosozumab were associated with positive contributions from both the cortical and trabecular bone compartments at both the lumbar spine and hip. Taken together, these findings suggest that romosozumab may offer patients with osteoporosis a new bone-forming therapeutic option that increases both vertebral and femoral strength within 12 months. © 2017 American Society for Bone and Mineral Research.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241937,"idioma_id":4,"titulo":"Botanical and geographical origin of honey from the dry and humid Chaco ecoregions (Argentina)","resumen":"To characterise the botanical and geographical origin of honey from the Chaco region (Argentina), 189 samples of honey were examined for pollen content using standard methodology. A general feature was the high representation of pollen from native arboreal plants, mainly of Fabaceae and the scarcity of pollen from herbaceous plants. One hundred and twenty-three samples proved to be unifloral. The most common were from: Prosopis alba, Helianthus annuus, Sarcomphalus mistol, Eugenia uniflora and Schinopsis balansae followed by those of Copernicia alba, Trithrinax schizophylla, Tessaria integrifolia, Baccharis- Eupatorium, Cynophalla retusa, Schinopsis lorentzii, Gleditsia amorphoides, Heimia salicifolia, Pisonia zapallo, Sagittaria montevidensis and Bulnesia sarmientoi. The pollen spectrum allowed the Dry and Humid Chaco ecoregions to be distinguished. The presence of pollen from cultivated crops and naturalised plants reflects a transitional complex between both ecoregions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241944,"idioma_id":4,"titulo":"Process analysis and global optimization for the microencapsulation of phytosterols by spray drying","resumen":"The response surface methodology (RSM) was used to optimize the microencapsulation of phytosterols by spray drying. The independent variables were drying air inlet temperature, atomization air flowrate, feed flowrate, phytosterols and total solids contents and the mass ratio between wall materials (Arabic gum and maltodextrin). The analyzed responses were process yield, mean volume particle size of product microparticles, phytosterols retention and encapsulation efficiency. Statistical analysis revealed that the selected independent variables, especially the atomization air flowrate and feed phytosterols content, significantly affect the studied responses. Taking into account the observed results and the analysis of variance, all the responses were successfully adjusted to second order models with interactions, showing good R2 values and correlating the experimental data properly. The product microparticles were also obtained by using the predicted optimal operating and formulation variables to test the validity of the quadratic models. The experimental responses were found to be in agreement with the predicted values and were within the acceptable limits, indicating the suitability of the model for predicting key parameters related to process performance and product quality. The recommended optimal formulation and operating conditions for microencapsulation of phytosterols by spray drying are: drying air temperature of 160 °C, atomization air and feed flowrates of 498 L\/h and 2.5 mL\/min (equivalent to 42 mm of height of rotameter and 7 % pump scale, respectively), phytosterols and total solids concentrations of 2 and 15 g\/100 mL, respectively, and mass ratio between Arabic gum and maltodextrin of 2.06. The process yield, encapsulation efficiency and phytosterols retention obtained under the optimum conditions were 84, 72 and 76 %, respectively. The product microparticles had a mean volume particle size of about 5 µm, well below the more restricted upper size limit of 25 &#956;m required to guarantee the incorporation of PS into the intestine micellar phase.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241945,"idioma_id":4,"titulo":"New pieces on genetic diversity and evolutionary history of hepatitis B virus: Characterization of the novel subgenotype F6","resumen":"New complete genome sequences of HBV genotype Ffrom Argentina were described and, based on the genetic divergenceand phylogenetic evidences, it is proposed to classify these new isolatesalong with the sequences previously reported as a novel ?subgenotypeF6?. Accordingly, it is considered that the accurate classification ofHBV subgenotypes and a more exhaustive sampling might providenew insights for understanding the evolutionary history of HBV genotypeF and proposing new hypotheses addressing its diversificationprocess.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241946,"idioma_id":4,"titulo":"Tissue tropism of Saint Louis encephalitis virus: Histopathology triggered by epidemic and non-epidemic strains isolated in Argentina","resumen":"Saint Louis encephalitis virus (SLEV) reemerged in South America, and caused encephalitis outbreaks at the beginning of the 21st century. To enhance our knowledge about SLEV virulence, we performed comparative pathogenesis studies in Swiss albino mice inoculated with two different variants, the epidemic strain CbaAr-4005 and the non-epidemic strain CorAn-9275. Only the infection of mice with SLEV strain CbaAr-4005 resulted in high viremia, invasion of peripheral tissues including the lungs, kidney, and spleen, and viral neuroinvasion. This was associated with inflammatory pathology in the lungs, spleen, and brain as well as morbidity and mortality. In contrast, neither signs of desease nor viral replication were observed in mice infected with strain CorAn-9275. Interestingly, important loss of B cells and development of altered germinal centers (GC) were detected in the spleen of mice infected with strain CbaAr-4005, whereas mice infected with SLEV CorAn-9275 developed prominent GC with conserved follicular architecture, and neutralizing antibodies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241947,"idioma_id":4,"titulo":"Environmental Surveillance of Enteroviruses in Central Argentina: First Detection and Evolutionary Analyses of E14","resumen":"Environmental surveillance is an effective approach to investigate the circulation of human enteroviruses in the population. Enteroviruses E14, CVA9, E-6, E16, E20, E25, E13, and CVA24 were detected in sewage and a watercourse in central Argentina. E14 was the most frequent serotype and was found for the first time in environmental samples in our region. Phylogenetic and coalescence analyses showed at least two recent introduction events.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241967,"idioma_id":4,"titulo":"The influence of fish bone morphology on aquatic transport: An experimental approach through elements of Creole perch (Percichthyidae: Percichthys trucha ; [Valenciennes, 1833])","resumen":"Many archaeological sites with fish remains are situated near ancient or current water courses. The origin of these time-averaged contexts requires an analysis considering possible non-human contributions and specifically the role of water as a highly selective agent. Element shape is a critical factor in all transport processes, but it has received little attention. The aim of this experimental work is to explore the hydrodynamic transport of fish bones considering the shape of anatomical elements. Different elements from Creole perch (Percichthyidae:Percichthys trucha; [Valenciennes, 1833]) individuals are utilized in dry conditions and under three different flow speeds. Transport groups, mode of transport and distance travelled are evaluated according to the shape of the elements. Fish vertebrae have the greatest transport potential. This experimental study indicates that hydrologic processes can impose biases giving a unique skeletal element composition in fish bone assemblages. A simplified differential transport model is proposed and an archaeological application of it is essayed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241968,"idioma_id":5,"titulo":"EXPLOTACIÓN DE PECES E INTENSIFICACIÓN EN AMBIENTES ÁRIDOS: COMPARANDO EL REGISTRO EN HUMEDALES DEL CENTRO OCCIDENTE DE ARGENTINA","resumen":"Este trabajo tiene por objetivo contribuir al conocimiento existente sobre la explotación de peces continentales en zonas áridas, en Sudamérica. El aprovechamiento de los peces para la subsistencia humana se aborda a partir de la evidencia zooarqueológica disponible en dos ambientes de humedales del centro-occidente de Argentina: las lagunas de Guanacache y Llancanelo. La explotación de este recurso permite discutir el proceso de intensificación propuesto para los últimos 2000 años en la región. La integración y comparación de la información ictioarqueológica, con la arqueofaunística en general, revela que la explotación de peces más antigua (ca. 3000 años a.P.) se registra en Llancanelo. En ambos humedales, el consumo de peces parece haber sido una estrategia que acompañó los primeros momentos de ocupación de las lagunas y estaría representando una adaptación al medio. Las tendencias temporales en los índices de abundancia y diversidad analizados no muestran evidencias de procesos de intensificación diferentes en ambos sectores. Finalmente, los peces representaron un recurso privilegiado tanto en Guanacache como en Llancanelo, cuyo consumo se vio complementado en ambos casos con el de otra fauna pequeña.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241970,"idioma_id":5,"titulo":"Identidades chinas en Buenos Aires: taiwaneses, chinos continentales y argenchinos.","resumen":"En este trabajo se abordó el carácter fluido y heterogéneo de las identidades de los migrantes chinos y sus descendientes nativos en Buenos Aires, particularmente de quienes emigraron desde la República de China (Taiwán) y la República Popular China entre fines de los años setenta del siglo XX y la actualidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241971,"idioma_id":4,"titulo":"Estudio preliminar sobre las propiedades de biocompatibilidad y osteoconductividad de un nuevo injerto de hueso bovino.","resumen":"Para prevenir la resorción post-exodoncia y preservar la integridad de los rebordes alveolares, se recomienda la colocación de injertos óseos en el momento de la extracción. Los injertos de hueso bovino son biocompatibles y osteoconductivos, permitiendo nueva aposición ósea por células osteoprogenitoras. Existen marcas internacionales de injertos de hueso bovino, pero resultan caros e incluso difíciles de adquirir. Por ello, la elaboración de biomateriales de alta calidad, nacionales, reduciría los altos costos de salud pública en odontología. En este estudio, se evaluaron y compararon los efectos de un injerto de hueso bovino fabricado en Argentina (Synergy Bone Matrix) versus un injerto de hueso bovino reconocido por sus efectos osteoconductivos (Bio-Oss), en el proceso de cicatrización ósea en un modelo experimental en ratas. Para ello, creamos un defecto óseo crítico en tibia de rata los cuales se rellenaron con uno de los injertos de hueso bovino o control. Se evaluó: respuesta clínica y radiográfica, densidad mineral ósea e histología. No se observaron abscesos, encapsulación, supuración o inflamación de los ganglios linfáticos. Radiográficamente, todos los implantes se integraron a los márgenes óseos circundantes, sugiriendo una cicatrización adecuada. Por el contrario, las tibias control no mostraron signos de recuperación con  formación de tejido fibroso. No se observaron diferencias estadísticas en las BMC y BMD entre las tibias Synergy Bone Matrix o Bio-Oss. La histología reveló partículas de ambos injertos óseos rodeadas por tejido óseo laminar indicando osteoconductividad sin signos inflamatorios. Este estudio preliminar sugiere que Synergy Bone Matrix presenta propiedades similares de biocompatibilidad y osteoconductividad que  Bio-Oss.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241972,"idioma_id":5,"titulo":"DESARROLLO DE UN MODELO EXPERIMENTAL DE OSTEONECROSIS DE MANDIBULA ASOCIADA AL TRATAMIENTO CRONICO CON AMINOBISFOSFONATOS","resumen":"La osteonecrosis de mandíbula asociada a  aminobisfosfonatos constituye un efecto secundario del tratamiento crónico con los más potentes. Un modelo experimental permitiría determinar la patogenia de dicha alteración. La oveja presenta características orales y del metabolismo óseo similar al humano y permite realizar manipulaciones bucales. Se evaluaron cambios clínicos, remodelamiento óseo y masa ósea maxilar en ovejas hembras adultas tratadas con zolendronato (ZOL), durante 22 meses y utilizando dosis equivalente al tratamiento de neoplasias. Seis ovariectomizadas (OVX ) recibieron ZOL; 5 OVX y 4 SHAM (control) recibieron solución fisiológica. A los 12 meses se extrajo  primer molar y biopsia de cresta iliaca. Al inicio, 4 y 22 meses se evaluó calcemia, fosfatemia, crosslaps (CTX) y fosfatasa alcalina ósea. Al final,  se evaluó contenido mineral óseo de la hemimandíbula superior (CMO: mg\/cm2). Al final del estudio, CTX disminuyó significativamente en ZOL (p<0.05) sin diferencias entre SHAM y OVX. En mandibula, los contenidos de Ca y P  (g\/g tejido) y CMO (g\/cm2) disminuyeron en OVX vs. SHAM (p<0.05) y sólo Ca y CMO respecto de ZOL (p<0.05). ZOL incrementó el contenido de Ca y CMO, mientras que el de P permaneció significativamente disminuido respecto de SHAM. La sobrevida en SHAM y OVX fue del 100% y en ZOL 77% (2 muertes);  2 ovejas del grupo  ZOL presentaron necrosis de mandíbula.  Conclusiones: fue posible obtener desarrollo de BRONJ por tratamiento crónico con ZOL, el cual redujo notablemente la resorción y según la relación Ca\/P, posiblemente haya afectado la mineralización ósea.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241973,"idioma_id":5,"titulo":"Marcadores de formación y resorción ósea y su utilidad para determinar el final del periodo de aposición ósea.","resumen":"La masa ósea pico (PMO) se alcanza entre 20 y 30 años, pero la aposición ósea continúa hasta alcanzar la fortaleza ósea (FO) adecuada. Se crea así una ventana que podría evaluarse bioquímicamente mediante marcadores óseos; la densidad mineral permanece constante. El objetivo fue determinar el fin de la aposición ósea mediante marcadores óseos. Se evaluaron 175 sujetos sanos (69 hombres y 70 mujeres, divididos por décadas entre 20 y 49 años de edad, determinando fosfatasa alcalina ósea (FAO) (Wiener optimizado), osteocalcina (OC), propéptido amino terminal del colágeno tipo I (P1NP) y telopéptido C-terminal del colágeno I (CTX) (Roche). Los marcadores, exceptuando FAO, correlacionaron negativamente con la edad (OC: r= -0,3; p<0.01;  PINP: r= -0,4; p<0,01 y CTX: r=-0,4; p<0,01). En hombres, P1NP y el CTX fueron mayores en 20-29 años vs. 30-39 años (p<0,01 y p<0,001, respectivamente) y vs 40-49 años (p<0,05; p<0,001, respectivamente). En mujeres OC, P1NP y CTX fueron mayores en 20-29 años vs. 30-39 años (p<0,001; p<0,0001 y p<0,01, respectivamente) y vs. 40-49 años (p<0.01; p<0.0001 y p<0.05, respectivamente). El final de la aposición ósea  determinada bioquímicamente según P1NP y CTX ocurrió: hombres entre 25-29 años y 30-34 años y mujeres: entre 30-34 años y 35-39 años (p<0.05).Conclusión: Los marcadores más sensibles y específicos permitirían determinar bioquímicamente el final de la aposición ósea. La detección temprana de inadecuación en lograr la óptima fortaleza ósea permitiría introducir modificaciones en ciertos hábitos y estilo de vida, como nutrición y ejercicios, mejorando la salud ósea","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241974,"idioma_id":4,"titulo":"Spatial patterns of soil resources under different land use in Prosopis woodlands of the Monte desert","resumen":"Changes in the spatial distribution of resources constitute an indicator of degradation of arid grazing lands. In arid and semi-arid ecosystems, the distribution of soil resources has been commonly associated with the structure and the spatial arrangements of the vegetation. Although the formation of fertile islands beneath vegetation patches is well documented, much less is known about the changes induced by grazing systems on the distribution of soil resources. We examine how pastoralist settlements are affecting the spatial distribution of soil resources and the soil nutrient balance in central-western woodlands of Argentina. We analyzed the distribution of soil water, chloride, nitrate, total nitrogen, and organic matter at increasing distances from livestock corrals and in undisturbed woodlands, at different soil depths. We also calculated variation indexes of soil organic matter and total nitrogen produced by livestock settlements, as an indicator of degree of deterioration or improvement of the soils. The transects located in pastoralist settlements demonstrated an increasing centripetal gradient in availability of soil water and nutrients compared to transects outside of these disturbed areas. Livestock corrals create local hotspots of nutrient enrichment, but when we analyzed the effects of livestock settlements at a higher spatial scale, we found net losses of soil organic matter and total nitrogen. We conclude that the coupling between nutrient and patch dynamics is disrupted by the pastoralist settlements, which caused a redistribution of soil resources, controlled by the location from the livestock corrals. The processes that promote nutrient losses, such as ammonium volatilization, denitrification, nitrate leaching, organic matter oxidation, manure exports, and soil erosion, are relatively higher than the extra inputs of dung and urine. Therefore, this study emphasizes the role of grazing systems as modulators of water and nutrient fluxes, and soil nutrient balance.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241976,"idioma_id":4,"titulo":"Livestock Settlement Dynamics in Drylands: Model application in the Monte desert (Mendoza, Argentina)","resumen":"Human settlements in arid environments are becoming widespread due to population growth, and without planning, they may alter vegetation and ecosystem processes, compromising sustainability. We hypothesize that in an arid region of the central Monte desert (Mendoza, Argentina), surface and groundwater availability are the primary factors controlling livestock settlements establishment and success as productive units, which affect patterns of degradation in the landscape. To evaluate this hypothesis we simulated settlement dynamics using a Monte Carlo based model of Settlement Dynamics in Drylands (SeDD), which calculates probabilities on a gridded region based on six environmental factors: groundwater depth, vegetation type, proximity to rivers, paved road, old river beds, and existing settlements. A parameter sweep, including millions of simulations, was run to identify the most relevant factors controlling settlements. Results indicate that distances to rivers and the presence of old river beds are critical to explain the current distribution of settlements, while vegetation, paved roads, and water table depth were not as relevant to explain settlement distribution. Far from surface water sources, most settlements were established at random, suggesting that pressures to settle in unfavorable places control settlement dynamics in those isolated areas. The simulated vegetation, which considers degradation around livestock settlements, generally matched the spatial distribution of remotely sensed vegetation classes, although with a higher cover of extreme vegetation classes. The model could be a useful tool to evaluate effects of land use changes, such as water provision or changes on river flows, on settlement distribution and vegetation degradation in arid environments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241977,"idioma_id":4,"titulo":"Ionic and stable isotope chemistry as indicators of water sources to the Mendoza river basin, Central Andes of Argentina","resumen":"REVISTA CON Q1 The Mendoza River is located in the North of Mendoza province (Argentina) with an average annual discharge of 47m3\/s, that provides water for domestic use, irrigation, industry, and hydroelectric energy generation for more than 1 million people. This water supply is mainly dependent on snow and ice melt from the Andes. Climate change may modify the spatial and seasonal patterns of precipitation and glacier melt: it is therefore important to quantify the relative contribution of each source to the river?s flow. We propose that differences in precipitation systems, geology, and sediment contact times of different surface areas and recharge sources provide differentiable chemical and stable isotopic signatures to the water, allowing the identification of its geographic and hydrologic origin. The two main north-south mountain ranges in this region- the Cordillera Frontal and Cordillera Principal- receive different contributions of precipitation from Atlantic and Pacific moisture sources. Waters from both mountain ranges have different stable isotope and ion chemistry. In addition, water derived from different ice bodies, snow, and groundwater, also differ in their stable isotope and\/or ion composition. This preliminary study indicates that it is possible to identify the relative contributions of precipitation from the Cordillera Principal and Cordillera Frontal and also identify the main water sources (groundwater, glacier, debris covered glacier and rock glacier) contributing to the streams of the Mendoza river basin.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":241999,"idioma_id":5,"titulo":"ECUACIÓN DE RESISTENCIA AL CAMBIO. APLICACIÓN DE LA ESCALA DE ANÁLISIS DE LA RESISTENCIA AL CAMBIO COMO HERRAMIENTA TERAPÉUTICA","resumen":"La presente investigación forma parte de una investigación de mayores proporciones en la que se diseña un modelo sistémico aplicado principalmente en los trastornos de pánico. La ?ecuación de resistencia al cambio? (ERC) es la sinergia entre cuatro factores: el grado de intensidad de los síntomas o problemas, la frecuencia de aparición, la cantidad de síntomas o problemas satélites que los conforman y por último, el tiempo de aparición. La ERC tiene como objetivo pronosticar el grado de resistencia al cambio del paciente desde la primera entrevista, como también explicar el efecto recaída y la compulsión a la repetición y, de esta manera, adecuar las estrategias y las intervenciones de manera más efectiva. Se desarrollará el aval teórico de la ecuación sobre el pivote de cuatro variables: cognitivas, interaccionales, emocionales y neurofi siológicas, y como ejemplo de su aplicación se mostrará sobre 30 casos en especifi cidad de trastornos de ansiedad en pánico con y sin agorafobia y fobias sociales. En este sentido, la propuesta es aplicar la ecuación a los problemas humanos en general.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242003,"idioma_id":4,"titulo":"Preparation of mesoporous titania xerogels under controlled synthesis conditions. Effects of processing in the textural, adsorption and photocatalytic properties","resumen":"A straightforward and potentially scalable procedure based in the Evaporation-Induced Self-Assembly (EISA) method has been used in order to synthesize mesoporous titania (TiO2) xerogels. The structural, textural and photocatalytic properties of the synthesized materials were determined. The variation of synthesis parameters relative humidity (RH) and temperature, allowed controlling the textural properties of materials that exhibited mesopores with controllable pore and neck diameter distributions in the range of 3?12 nm, large surface area (125?161 m2 g&#8722;1) and pore volume values between 0.17 and 0.38 cm3 g&#8722;1. Selected area electron diffraction (SAED) and X-ray diffraction (XRD) patterns indicated the presence of anatase phase. The uptake of gallic acid (GA) on these mesoporous powders and Evonik Degussa P25 was measured using Fourier Transform IR (FTIR) spectroscopy. The photocatalytic degradation rates of GA adsorbed on TiO2 were measured and followed by FTIR. The mesoporous materials showed interesting features including efficient trapping of the adsorbate and good photolytic response. The catalysts were exposed to successive cycles of adsorption\/photolysis of GA and a very good performance was observed for the mesoporous anatase samples, leading to efficient, recoverable and reusable photocatalysts.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242005,"idioma_id":4,"titulo":"Kinetic control of aqueous polymerization using radicals generated in different spin states","resumen":"1) Background: Magnetic fields can interact with liquid matter in a homogeneous and instantaneous way, without physical contact, independently of its temperature, pressure and agitation degree and without modifying recipes nor heat and mass transfer conditions. In addition, magnetic fields may affect the mechanisms of generation and termination of free radicals. This paper is devoted to the elucidation of the appropriate conditions needed to develop magnetic field effects for controlling the kinetics of polymerization of water soluble monomers. 2) Methods:  Thermal and photochemically initiated polymerizations were investigated at different initiator and monomer concentrations, temperatures, viscosities and magnetic field intensities. 3) Results: Significant magnetic field impact on the polymerization kinetics was only observed in photochemically initiated polymerizations carried out in viscous media and performed at relatively low magnetic field intensity. Magnetic field effects were absent in polymerizations in low viscosity media and thermally initiated polymerizations performed at low and high magnetic field intensities. The effects were explained in terms of the radical pair mechanism for intersystem crossing of spin states. 4) Conclusion: Polymerization kinetics of water soluble monomers can be potentially controlled using magnetic fields only under very specific reaction conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242006,"idioma_id":4,"titulo":"Structure and properties of biocompatible poly(glycerol adipate) elastomers modified with ethylene glycol","resumen":"p { margin-bottom: 0.25cm; line-height: 120%; }Polyesterspoly(glycerol adipate)s or PGAs were prepared through a catalyst-freepolycondensation reaction involving different proportions of adipicacid and glycerol. Additionally, another set of PGAs was formulatedby adding ethylene glycol to the reaction mixture, creating threePGA-co-ethylene glycols of different ethylene glycol-to-glycerolratios. All prepolymers were chemically crosslinked into elastomericfilms according to specific experimental conditions. A fullcharacterization of elastomers revealed an ease of tunabilityaccording to monomer ratios and curing conditions. Mechanicalproperties presented a variety of Young?s modulus values rangingfrom 0.07 to 8.33&#8201;MPa. Within this range, a number of Young?smodulus values of soft tissues can be included. Moreover, acytotoxicity analysis performed on embryonic mouse fibroblasts(NIH\/3T3) showed an absence of cytotoxicity and good adherence overall PGA and PGA-co-ethylene glycol elastomers. In addition,fibroblasts underwent a differentiation process into neuron-likecells, thus exhibiting excellent potential for soft tissueengineering.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242007,"idioma_id":4,"titulo":"Novel poly (diol sebacate)s as additives to modify Paclitaxel release from poly (lactic-co-glycolic acid) thin films","resumen":"Paclitaxel (PTX) incorporation in poly (lactic acid-co-glycolic acid) (PLGA) matrices produce films with high tensile rigidity and slow release that fail to deliver the required release rate for most biomedical applications such as in drug eluting stents and cancer treatments. To modify and improve this behavior, a set of poly (diol sebacate)s were synthesized and fully characterized as possible additives. The tensile properties of PLGA blends were evaluated as these materials could be used as coatings in drug eluting stent applications. A significant improvement of mechanical flexibility was observed with 20 % additive content, as it reduced the Young´s Modulus (YM) value and increased the maximum deformation at break. PTX release was studied and correlated with the release of additive from PLGA films. An increase of the initial burst release phase was observed on all blends when compared to the control films of PLGA. Modulation of PTX release was achieved by altering the hydrophilicity degree of the additive or its percentage content on the blend. This supports the possibility that PTX was partitioned into the additive phase. Cytotoxicity analyses of novel additives were performed on mouse embryonic fibroblasts NIH\/3T3","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242010,"idioma_id":4,"titulo":"Effect of methoxyl groups on the NMR spectra: configuration and conformation of natural and synthetic indanic and tetralinic structures","resumen":"Here, we studied the influence of the methoxyl groups attached at C-7 and C-2&#8242; of natural and synthetic 1-arylindanes on the chemical shift of the signal of bibenzylic hydrogen and carbon atoms and J1,2 coupling constants. This influence was also analysed in natural 1-aryltetralins and related compounds that possess methoxyl and\/or hydroxyl groups bound at C-8 and C-2&#8242;. The methoxyl groups attached at C-7 in indanes or at C-8 in tetralins produce a deshielding signal at H-1 and shield at C-1 and a strong decrease in the value of J1,2 due to the pseudoequatorial location adopted by the aryl group bound at C-1, avoiding an ?A1,3 strain?. Furthermore, compounds with hydroxyl or methoxyl groups in C-2&#8242;, in the absence of substituents of C-7 or C-8, present a strong deshielding signal at H-1, strong shield of the C-1 signal and a decrease in the value of J1,2. This is attributed to the stereoelectronic effects of the methoxyl or hydroxyl groups, which we have called ?Asarone effect?. NOESY experiments were conducted to confirm the configuration and conformation of some of the compounds included in this work. This study shows that both effects, A1,3 strain and Asarone effect, must be taken into account when the structure of natural indanes and tetralins is analysed by using 1H-NMR and 13C-NMR spectra.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242025,"idioma_id":5,"titulo":"PROCESOS DE METROPOLIZACIÓN Y POLÍTICAS DE REVITALIZACIÓN URBANA, REVISIÓN DE EXPERIENCIAS Y APORTES","resumen":"Los métodos de planificación tradicionalmente empleados no han logrado detener este proceso de expansion urbana, ni tampoco mitigar sus consecuencias no deseadas. Históricamente, en el NEA y en particular en la provincia del Chaco se han formulado diversos planes integrales que, en su gran mayoría, no lograron los fines propuestos. En consecuencia, el marcado crecimiento de la ciudad, sumado a la desarticulación de programas y proyectos, muestran la necesidad de coordinar esfuerzos y estrategias que orienten inversiones en las áreas que así lo requieren, con el fin de promover un crecimiento sostenible, conocido también como ?crecimiento inteligente? que, armonice el desarrollo económico, social y cultural de su población.  Para lograr este objetivo, es crucial abordar la exploración de iniciativas, instrumentos, enfoques y estrategias de planeamiento que se adecuen a las necesidades de las ciudades del presente y que permitan mejorar los mecanismos de toma de decisiones y la gobernabilidad de los asentamientos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242033,"idioma_id":4,"titulo":"Circular Natural Geoforms, Sierras Pampeanas, Argentina","resumen":"Circular natural geoforms","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242034,"idioma_id":4,"titulo":"Sex differences in the development of prolactinoma in mice overexpressing hCGb: Role of TGF1","resumen":"Female transgenic mice that overexpress the human chorionic gonadotrophin &#946; subunit (hCG&#946;+) develop prolactinomas, whereas hCG&#946;+ males do not. The high levels of circulating hCG induce massive luteinization in the ovary of hCG&#946;+ females, and progesterone becomes the primary steroid hormone produced, but estradiol remains at physiological level. The involvement of high levels of progesterone in lactotroph proliferation is not clearly understood; hence, the pathogenesis of prolactinomas in hCG&#946;+ females remains unclear. TGF&#946;1 is an inhibitor of lactotroph function, and the reduced TGF&#946;1 activity found in prolactinomas has been proposed to be involved in tumor development. The aim of the present work was to study the role of TGF&#946;1 in the gender-specific development of prolactinomas in hCG&#946;+ mice. We compared the expression of different components of the pituitary TGF&#946;1 system in males and females in this model. We found reduced TGF&#946;1 levels, reduced expression of TGF&#946;1 target genes, TGF&#946;1 receptors, Ltbp1, Smad4 and Smad7 in hCG&#946;+ female pituitaries. However, no differences were found between the transgenic and wild-type male pituitaries. We postulate that decreased pituitary TGF&#946;1 activity in hCG&#946;+ females is involved in the development of prolactinomas. In fact, we demonstrated that an in vivo treatment carried out for increasing pituitary TGF&#946;1 activity, was successful in reducing the prolactinoma development, and the hyperprolactinemia in hCG&#946;+ females. Moreover, the stronger TGF&#946;1 system found in males could protect them from excessive lactotroph proliferation. Sex differences in the regulation of the pituitary TGF&#946;1 system could explain gender differences in the incidence of prolactinoma.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242035,"idioma_id":4,"titulo":"Sex differences in the pituitary TGFbeta1 system; the role of TGFbeta1 in prolactinoma development.","resumen":"Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in tumor size, behavior and incidence have been described. These differences have been associated with earlier diagnosis in woman, as well as with serum estradiol levels. Experimental models of prolactinomas in rodents also show a higher incidence in females, and recent findings suggest that gender differences in the transforming growth factor beta 1 (TGF&#946;1) system might be involved in the sex-specific development of prolactinomas in these models. The aim of this review is to summarize the literature supporting the important role of TGF&#946;1 as a local modulator of pituitary lactotroph function and to provide recent evidence for TGF&#946;1 involvement in the sex differences found in prolactinoma development in animal models.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242036,"idioma_id":5,"titulo":"Medición del coeficiente de acoplamiento mutuo entre bobinas ligeramente acopladas, en el laboratorio de Física III","resumen":"Se propone un método de medición del coeficiente de inducción mutua M, entre dos bobinas, con generador de señales senoidales y osciloscopio. Las bobinas estarán separadas entre sí a distintas distancias, estando acopladas en forma axial y fuera de eje con distintos ángulos. Se puede observar la conformación del campo magnético en bobinas, plana y solenoide. Los resultados se obtienen variando la frecuencia de la señal senoidal de acoplamiento. Se considera los efectos de capacidad distribuida. Se comparan resultados con cálculos teóricos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242037,"idioma_id":4,"titulo":"Thermodynamics of the melting process in Au nano-clusters: Phenomenology, energy, entropy and quasi-chemical modeling","resumen":"The paper presents a thermodynamic study of the melting transition in Au nano-clusters with a number of atoms (N) in the range using a Molecular Dynamics (MD) technique. This range of sizes allows an analysis of the relations between the properties of the clusters and macroscopic Au. Four steps in the progress of the transition occurring upon heating are identified on thermodynamic and structural basis, and the corresponding temperature ranges are determined. In particular, the step where most of the transition takes place (the 'melting step') is identified and described in terms of the change in the relative amount of two kinds of atoms, viz., those forming solid phase-like (SPL) aggregates and those in the liquid phase-like (LPL) aggregates. The energy and entropy change involved in the ?melting step? are established as a function of N. These properties are used to evaluate the temperature at which the SPL and the LPL have equal values of the Helmholtz energy. Furthermore, the possibility of describing the thermodynamics of the ?melting step? by means of a formalism involving an isomerization-type reaction between the atoms in the SPL and the LPL is explored. To this aim, an equilibrium constant ( Keq) involving the concentration of such types of atoms is introduced. Finally, it is shown that a thermodynamic, van´t Hoff analysis of the size-dependence of yields values of the temperature which are in very good agreement with those obtained from the energy and entropy values","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242041,"idioma_id":4,"titulo":"Diacetylenic lipids in the design of stable lipopolymers able to complex and protect plasmid DNA","resumen":"Different viral and non-viral vectors have been designed to allow the delivery of nucleic acids in gene therapy. In general, non-viral vectors have been associated with increased safety for in vivo use; however, issues regarding their efficacy, toxicity and stability continue to drive further research. Thus, the aim of this study was to evaluate the potential use of the polymerizable diacetylenic lipid 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine (DC8,9PC) as a strategy to formulate stable cationic lipopolymers in the delivery and protection of plasmid DNA. Cationic lipopolymers were prepared following two different methodologies by using DC8,9PC, 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), and the cationic lipids (CL) 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP), stearylamine (SA), and myristoylcholine chloride (MCL), in a molar ratio of 1:1:0.2 (DMPC:DC8,9PC:CL). The copolymerization methodology allowed obtaining cationic lipopolymers which were smaller in size than those obtained by the cationic addition methodology although both techniques presented high size stability over a 166-day incubation period at 4&#730;C. Cationic lipopolymers containing DOTAP or MCL were more efficient in complexing DNA than those containing SA. Moreover, lipopolymers containing DOTAP were found to form highly stable complexes with DNA, able to resist serum DNAses degradation. Furthermore, neither of the cationic lipopolymers (with or without DNA) induced red blood cell hemolysis, although metabolic activity determined on the L-929 and Vero cell lines was found to be dependent on the cell line, the formulation and the presence of DNA. The high stability and DNA protection capacity as well as the reduced toxicity determined for the cationic lipopolymer containing DOTAP highlight the potential advantage of using lipopolymers when designing novel nonviral carrier systems for use in in vivo gene therapy. Thus, this work represents the first steps toward developing a cationic lipopolymer-based gene delivery system using polymerizable and cationic lipids.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242042,"idioma_id":4,"titulo":"Ambient Species Density and Gas Temperature Radial Profiles Derived from a Schlieren Technique in a Low- Frequency Non-thermal Oxygen Plasma Jet","resumen":"Abstract A quantitative interpretation of the schlieren technique applied to a non-thermalatmospheric-pressure oxygen plasma jet driven at low-frequency (50 Hz) is reported. Thejet was operated in the turbulent regime with a hole-diameter based Reynolds number of13,800. The technique coupled to a simplified kinetic model of the jet effluent regionallowed deriving the temporally-averaged values of the gas temperature of the jet byprocessing the gray-level contrast values of digital schlieren images. The penetration of theambient air into the jet due to turbulent diffusion was taken into account. The calibration ofthe optical system was obtained by fitting the sensitivity parameter so that the oxygenfraction at the nozzle exit was unity. The radial profiles of the contrast in the discharge offcase were quite symmetric on the whole outflow, but with the discharge on, relativelystrong departures from the symmetry were evident in the near field. The time-averaged gastemperature of the jet was relatively high, with a maximum departure of about 55 K fromthe room temperature; as can be expected owing to the operating molecular gas. Theuncertainty in the temperature measurements was within 6 K, primarily derived fromerrors associated to the Abel inversion procedure. The results showed an increase in the gastemperature of about 8 K close to the nozzle exit; thus suggesting that some fast-gasheating (with a heating rate *0.3 K\/ls) still occurs in the near field of the outflow.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242043,"idioma_id":4,"titulo":"A COMPROMISING POSITION FOR A VARIANT: A NEW ALLELE FOR D1S1656 THAT INVADES ITS NEIGHBORS AND CAN LEAD TO MISSINTERPRETATIONS","resumen":"Short tandem repeats (STRs) are the markers of choice for purposes of human forensic identification because of their considerable degree of polymorphism. This variability may occasionally become a challenge for the analyst when a new variant invades the allele distribution range of the neighboring locus. We present here a novel variant at locus D1S1656 showing a molecular length of 211.32&#8197;bp corresponding to 21.3 repeating units. This variant is superimposed on the D12S391 locus when the Global Filer? (Thermo Fisher Scientific Inc., USA) is used, invading the shortest allele range and being assigned as Off-ladder (OL). In contrast, typing with PowerPlex® Fusion (Promega Corp., Madison, USA) overlaps the D2S441 locus, generating an allele that is recognized as 8. In both cases the invasion was observed as a tri-allele pattern. The results were confirmed by DNA re-extraction and typing with the two independent commercial megaplexes described above. The variant was detected during analysis of a reference sample throughout a paternity exclusion case. This is the first time this variant has been described and reported to the NIST STR Base. Since D1S1656 is included in widely-used multiplex kits from several vendors - Biotype (Dresden, Germany) Qiagen (Venlo, The Netherlands), Promega (Madison, USA) and Thermo Fisher (Foster City, CA, USA) - it would then be recommendable that other forensic labs be aware of this new micro-variant in dealing with similar interpretation challenges and that the kit producers take this fact into account in designing new multiplex kits.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242045,"idioma_id":4,"titulo":"The botanical monoterpenes linalool and eugenol hyperactivate and flush-out nymphs of Triatoma infestans","resumen":"Monoterpenes are the main components of essential oils. Some members of this chemical family present insecticidal activity. Triatoma infestans is the main vector of Chagas disease in Argentina, Bolivia, Paraguay and Perú. The objective of this work was to evaluate the effect of six monoterpenes (1,8-cineole, eugenol, linalool, menthol, &#945;-terpineol and thymol) on the locomotor and flushing out activity of T. infestans. A video tracking technique was used to evaluate the locomotor activity of nymphs exposed to different concentrations of these chemicals applied as films on filter paper. Papers treated with acetone alone were used as negative controls, while solutions of tetramethrin were applied as positive controls. Only linalool and menthol produced hyperactivation. Flushing out was assessed under laboratory conditions using a standardized aerosolization method. All monoterpenes were applied at 1.5 g\/m3. 1,8-Cineole, &#945;-terpineol and thymol flushed out 10% or less nymphs. The average flushing out produced by eugenol was 36.7%. Values of Median Flushing out Time (FT50) could only be calculated for linalool and menthol (16.67 and 42.98 min, respectively). The FT50 value for the positive control tetramethrin (applied at 0.006 g\/cubic meter) was 8.29 min. Following these results, the flushing out activity of a mixture of linalool and eugenol was evaluated. The FT50 of this 2:1 linalool:eugenol mixture was 40.73 min. Finally, flushing out assays performed in semi-field conditions showed similar results to those obtained at the laboratory.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242046,"idioma_id":4,"titulo":"Attenuation by clouds of UV radiation for low stratospheric ozone conditions","resumen":"Stratospheric poor ozone air masses related to the polar ozone hole overpass subpolar regions in the Southern Hemisphere during spring and summer seasons, resulting in increases of surface Ultraviolet Index (UVI). The impact of these abnormal increases in the ultraviolet radiation could be overestimated if clouds are not taking into account. The aim of this work is to determine the percentage of cases in which cloudiness attenuates the high UV radiation that would reach the surface in low total ozone column situations and in clear sky hypothetical condition for Río Gallegos, Argentina. For this purpose, we analysed UVI data obtained from a multiband filter radiometer GUV-541 (Biospherical Inc.) installed in the Observatorio Atmosférico de la Patagonia Austral (OAPA-UNIDEF (MINDEF - CONICET)) (51 °33´ S, 69 °19´ W), Río Gallegos, since 2005. The database used covers the period 2005-2012 for spring seasons. Measured UVI values are compared with UVI calculated using a parametric UV model proposed by Madronich (2007), which is an approximation for the UVI for clear sky, unpolluted atmosphere and low surface albedo condition, using the total ozone column amount, obtained from the OMI database for our case, and the solar zenith angle. It is observed that &#8764;76% of the total low ozone amount cases, which would result in high and very high UVI categories for a hypothetical (modeled) clear sky condition, are attenuated by clouds, while 91% of hypothetical extremely high UVI category are also attenuated.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242047,"idioma_id":4,"titulo":"Study of UV cloud modification factors in Southern Patagonia","resumen":"Anthropogenic perturbation of the ozone layer has induced change in the amount of UV radiation that reaches the Earth´s surface, mainly through the Antarctic ozone hole, making the ozone and ultraviolet (UV) radiation two important issues in the study of Earth atmosphere in the scientific community. Also the clouds have been identified as the main modulator of UV amount in short time scales and produce the main source of uncertainty in the projection of surface UV level as consequence of projected ozone recovery. While clouds can decrease direct radiation, they can produce an increase in the diffuse component, and as consequence the surface UV radiation may be higher than an equivalent clear sky scenario for several minutes. In particular this situation can be important when low ozone column and partially cloud cover skies happen simultaneously. These situations happen frequently in southern Patagonia, where the CEILAP Lidar Division has established the Atmospheric Observatory of Southern Patagonia, an atmospheric remote sensing site near the city of Río Gallegos (51°55´S, 69°14´W). In this paper, the impact of clouds over the UV radiation is investigated by the use of ground based measurements from the passive remote sensing instruments operating at this site, mainly of broad and moderate narrow band filter radiometers. We analyzed the UV Index obtained from a multiband filter radiometer GUV-541 (UVI) [Biospherical Inc.] installed in the Observatorio Atmosférico de la Patagonia Austral, Río Gallegos, since 2005. Cloud modification factors (CMF, ratio between the measured UV radiation in a cloudy sky and the simulated radiation under cloud-free conditions) are evaluated for the study site. The database used in this work covers the period 2005-2012 for spring and summer seasons, when the ozone hole can affect these subpolar regions. CMF higher than 1 are found during spring and summer time, when lower total ozone columns, higher solar elevations and high cloud cover occur simultaneously, producing extreme erythemal irradiance at ground surface. Enhancements as high as 25% were registered. The maximum duration of the enhancement was around 30 minute. This produces dangerous sunbathing situations for the Río Gallegos citizen.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242048,"idioma_id":4,"titulo":"Mapping inundation probability due to increasing sea level rise along El Puerto de Santa Mar&iacute;a (SW Spain)","resumen":"Global sea levels have risen through the twentieth and twenty-first centuries. This rise will almost certainly continue and probably accelerate during the rest of the twenty-first century, albeit there is strong disagreement about the range of future sea level rise due to uncertainties regarding scenarios and emission of greenhouse gasses. Although the impacts of sea level rise are diverse, inundation during high tides is one of the most obvious and immediate consequences. A probabilistic methodology for mapping the inundation hazard because of sea level rise has been applied to the coast of El Puerto de Santa María in the province of Cádiz in southwest Spain. This methodology involves a step forward since represents the full range of probabilities, associated with each scenario of sea level rise considered, and thus offers a more realistic view of the probability of inundation in each area. Results show large differences in the spatial distribution of probable inundation in urban areas and wetlands leading to different consequences for management actions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242052,"idioma_id":5,"titulo":"Desarrollo de habilidades cognitivas asociadas a las gráficas de datos experimentales en estudiantes de ingeniería: su incidencia en la modelización","resumen":"La presente investigación se orientó hacia el reconocimiento de rasgos que, vinculados al desarrollo de ciertas habilidades cognitivas, inciden en la modelización de fenómenos físicos, teniendo como eje principal la ela-boración, tratamiento y análisis de gráficas cartesianas en el marco de las prácticas experimentales de física básica universitaria. Se adoptó una metodología de carácter cualitativo basada en un estudio de caso de tres estudiantes de carreras de ingeniería. Se evidenció que los aspectos aún no desarrollados en la construcción del modelo gráfico, fundamentalmente la adopción de una curva de ajuste, se constituyen en obstáculos al momento de atribuir significado a la información contenida en la GC, a partir del conocimiento conceptual disponible, condicionando las interconexiones entre los modelos gráfico, matemático y conceptual.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242053,"idioma_id":5,"titulo":"Propuesta didáctica para la enseñanza de sonido en una Tecnicatura en Higiene y Seguridad en el Trabajo","resumen":"Se presenta una propuesta didáctica relacionada con la unidad temática Sonido correspondiente a la actividad curricular Física I de la carrera Técnico Superior en Higiene y Seguridad en el Trabajo. La brecha existente entre lo que la escuela media ofrece sobre los contenidos relacionados con la producción, propagación y percepción del sonido y las demandas de la sociedad actual al futuro Técnico Superior se constituyó en uno de los aspectos motivadores para el diseño y elaboración de la propuesta.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242054,"idioma_id":5,"titulo":"correlation between virulence markers of Helicobacter pylori in oral cavity and gastric biopsies","resumen":"BACKGROUND:The clinical outcome of Helicobacter pylori infection has been associated with virulence factors. The presence of these factors is useful as molecular markers in the identification of the high risk for developing severe gastric pathologies.OBJECTIVE:To correlate the presence of virulence markers cagA and bab2A of H. pylori in oral and gastric biopsy samples.METHODS:An observational, prospective, descriptive, and cross-sectional study was carried out between September 2011 and September 2012. Patients suffering dyspepsia with indication for upper gastrointestinal video endoscopy who attended the Gastroenterology Service of the Hospital Dr. Julio C. Perrando were included. Epidemiological investigation was completed. To detect the bacteria and their virulence genes, samples of saliva, dental plaque and gastric biopsy were taken and processed by PCR.RESULTS:Sixty-one patients were selected for this study (30 women and 31 men). H. pylori was detected in 31 gastric biopsies and 31 oral samples. Significant difference between oral and gastric samples was found in cagA genotype. Agreement between oral and gastric genotypes was found in 38.7% of samples from the same patient.CONCLUSION:This study is the first in provide information about the genotypes of the Argentinean Northeast H. pylori strains. Despite the high prevalence of H. pylori infection, the most of patients had less virulent genotypes in oral cavity and gastric tissue. The cagA \/ babA2 combination was not frequent in the samples studied. There was not a statistical correlation between the virulence genes and gastroduodenal or oral diseases. Although in some patients the same genotype was found both in oral and gastric samples, it cannot be ensure that they corresponding to the same strain because a DNA sequencing was not performed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242055,"idioma_id":4,"titulo":"Impact of Mobile Marketing on passengers? satisfaction and experience at airports.","resumen":"The availability of new airport applications helps passengers manage their time at airports in an efficient way, inasmuch as these applications provide real-time information. The results of this study confirm the fact that the multifunctionality of the mobile marketing tool favours the effectiveness of the processes carried out by passengers at the airport. The main objectives of this research are to analyse the basic concepts around mobile marketing and mobile applications, and to assess the impact of this tool on the levels of user satisfaction and improvement in the image\/perception of airports thanks to the app. This study will help to achieve a better understanding of the interaction between the airport and passengers through the use of smartphones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242058,"idioma_id":4,"titulo":"Agriculturisation and trade-offs between commodity production and cultural ecosystem services: A case study in Balcarce County","resumen":"Increased production of commodities in Latin America has transformed the rural landscape with a potential loss of cultural ecosystem services (CES). The aim of our study was to assess the extent and mechanisms by which the agriculturisation process in Balcarce County in the Pampas region of Argentina has affected the supply of CES of the rural landscape and consequently, the well-being of local inhabitants. Data were obtained through exploratory interviews with selected inhabitants of Balcarce County (Argentina). We focused on people´s perceptions regarding landscape changes in the last two decades and the rural landscape aspects that provide identity, sense of place and cultural heritage. Interviews were qualitatively analyzed through content analysis. Results showed that twenty years ago the landscape sustained food provision along with CES. Agriculturisation has implied an undeniable increase of commodity production (i.e. soybean) and economic benefits at the expense of a significant loss of natural environments and changes in the rural livelihoods that sustain CES. The sierras (low mountains) emerge as the last remnants of natural environments sustaining identity, sense of place and cultural heritage.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242065,"idioma_id":5,"titulo":"ENERGÍAS Y TERRITORIOS EN ARGENTINA: recursos no convencionales de principios de siglo XXI","resumen":"En Argentina, en el siglo XXI, se buscaría desarrollar una energía más durable. El Estado se ha reposicionado en el sector de la energía, invirtiendo en obras y regulando la actividad. Se apuesta a desarrollar hidrocarburos no convencionales y se promueven las energías renovables no convencionales. Legislación favorable, incentivos económicos y garantías de compra, constituyen los principales motores para el desarrollo de esas energías. Las nuevas tecnologías, que asocian infraestructura y flujos de energía a los de información, también forman parte de las agendas institucionales. La integración regional constituye un reaseguro, para brindar mayor flexibilidad al sistema. No obstante, la escasa de planificación y la ausencia de decisiones políticas a largo plazo contribuyen a un panorama actual de crisis energética. Se plantea un análisis de la evolución en la explotación de recursos no convencionales, en una transición a un sistema más diversificado, que privilegiaría la inclusión social.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242066,"idioma_id":5,"titulo":"LAS MARCAS DE LA MINERÍA EN DOS LOCALIDADES DEL OESTE CATARMARQUEÑO, ARGENTINA","resumen":"A finales del siglo XX, se promovió atraer fuertemente capital trasnacional a distintos sectores de la economía argentina, a través de políticas, legislación e incentivos ventajosos. Así se cobró impulso la minería a cielo abierto en Catamarca. Su explotación se realiza fuera de sectores urbanos, pero los efectos que genera su proceso productivo se difunden ampliamente en la salud y el ambiente, en las relaciones sociales, en las estructuras de gobierno local y provincial. El trabajo que se presenta analiza las transformaciones en Belén y Hualfín, dos localidades cercanas a Bajo La Alumbrera, como espacios receptores de grandes inversiones que se presentan bajo discursos de desarrollo. Se analiza la relación de la minería con las actividades productivas y las demandas de las poblaciones locales&#894; las transformaciones económicas, productivas, políticas, ambientales, sociales y habitacionales en esas localidades y la región a partir de la irrupción de la minera","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242067,"idioma_id":5,"titulo":"Fronteras y frentes energéticos en Argentina","resumen":"Los frentes energéticos avanzan en Argentina, desde principios del siglo XX. Las fronteras que crean, todavía continúan moviéndose, pero con propósitos y actores renovados. Los primeros grandes emprendimientos y obras fueron impulsados con los objetivos mayores de 1) abastecer los grandes centros de consumo y 2) contribuir a la integración de los territorios periféricos de la Nación. Los proyectos binacionales han contribuido a su vez, a construir las bases para la integración regional. A principios del siglo XXI, la búsqueda planetaria de una transición a energías renovables propicia cambios socio-tecnológicos que promueven nuevos frentes productivos. Las políticas públicas energéticas dan marco a los cambios en los sistemas y las transformaciones territoriales. En las nuevas fronteras, con proyectos de valorización de recursos naturales para aprovechamientos energéticos, los espacios periféricos podrían encontrar oportunidades de reposicionamiento e integración.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242072,"idioma_id":5,"titulo":"USO DE ÁCIDOS ORGÁNICOS EN MEDIAS RESES EQUINAS","resumen":"La contaminación microbiana de los canales que ocurre durante la faene es indeseable e inevitable. Aunque la contaminación puede provenir del ambiente de trabajo, la fuente primaria puede originarse a partir del mismo animal, en el que pueden habitar bacterias patógenas como Escherichia coli, Salmonella y Listeria, las cuales implican amenazas para la salud humana. En este contexto, el objetivo del presente trabajo fue evaluar la eficacia de la aspersión de ácido láctico a diferentes diluciones en la superficie de reses de equinos, despues del lavado con agua, con la intencios de alcanzar una reducción de entorobacterias totales y recuento de aerobios totales. Los resultados generales sugieren una dilución mínima de aplicación del 2% de ácido láctico a 55 Grados a los efectos de obtener un resultado beneficioso en el recuento inicial de la generalidad de los microorganismos considerados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242075,"idioma_id":4,"titulo":"Nanotoxicological and teratogenic effects: A linkage between dendrimer surface charge and zebrafish developmental stages","resumen":"This article reports novel results about nanotoxicological and teratogenic effects of the PAMAM dendrimers DG4 and DG4.5 in zebrafish (Danio rerio). Zebrafish embryos and larvae were used as a rapid, high-throughput, cost-effective whole-animal model. The objective was to provide a more comprehensive and predictive developmental toxicity screening of DG4 and DG4.5 and test the influence of their surface charge. Nanotoxicological and teratogenic effects were assessed at developmental, morphological, cardiac, neurological and hepatic level. The effect of surface charge was determined in both larvae and embryos. DG4 with positive surface charge was more toxic than DG4.5 with negative surface charge. DG4 and DG4.5 induced teratogenic effects in larvae, whereas DG4 also induced lethal effects in both zebrafish embryos and larvae. However, larvae were less sensitive than embryos to the lethal effects of DG4. The platform of assays proposed and data obtained may contribute to the characterization of hazards and differential effects of these nanoparticles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242076,"idioma_id":4,"titulo":"A comparison of spectral macroalgae taxa separability methods using an extensive spectral library","resumen":"Remote sensing is one the most promising approaches to coastal area cartography, including mapping algae forests. After discrimination of algal communities from other benthic habitats, next step is species discrimination (from other algae). Spectral signature provides the most complete remote description to characterize any algae. In this work spectral signatures are studied from the point of view of taxa separability to assess the potential use of remote sensors to map seaweed in coastal waters. Three approaches were tested: Red-Green-Brown colorimetry (sRGB), optimal spectral boundary separation based on True Skill Statistics (TSS-OB), and pigment absorbance band detection by Derivative Spectroscopy (DS). An extensive spectral library of 36 algal species present in the Atlantic Galician coast (NW of Spain) is used to test and validate these methods. The results show that the three broad taxa of red, green and brown algae can be separated by all three methods (Cohen´s kappa of 0.697, 0.891 and 0.910, respectively). The TSS-OB and the DS approaches provide almost perfect classification (despite some anomalous specimens), with DS being slightly better. The sRGB approach, useful for in situ photographic classification, also provides good results.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242077,"idioma_id":4,"titulo":"Seascape modeling of southern giant petrels from Patagonia during different life-cycles","resumen":"Presence-only models such as Ecological Niche Factor Analysis (ENFA) compare distributions of environmental variables and species, generating habitat suitability (HS) maps. Here, we determined the factors affecting distribution of southern giant petrels (SGP) from northern Patagonian colonies (Isla Arce: 45° 00&#697;S; 65°29&#8242;W, and Isla Gran Robredo: 45°08&#697;S; 66°03&#8242;W) using ENFA, improving estimates of their potential year-round feeding habitats. Data on movements of 17 adult and 9 first-year juvenile SGP were gathered using satellite telemetry. Model eco-geographical variables (EGV) overlapped the tracked animals. The resulting HS maps included most of the tracking locations along the Argentinean Shelf and reflected characteristics that congregate procellariiformes elsewhere. Wind conditions and primary productivity shaped foraging HS of petrels over the year. However, different EGVs influenced this population differently depending on the requirements of their life stage. For example, juveniles showed high marginality (values of EGVs different from the mean values available). Breeding adults´ HS was determined by a small range of values within those available, showing high specializations. Contrarily, wintering petrels showed plasticity in the selection of their foraging environments being distribution of fisheries one of the variables influencing their distribution. This study highlights the importance of the Argentinean Shelf for conservation of the marine environment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242078,"idioma_id":4,"titulo":"The management performance of marine protected areas in the North-east Atlantic Ocean","resumen":"In the North-east Atlantic Ocean there are 550 inshore and offshore MPAs established to accomplish a high diversity of objectives, which can be classified into 24 different types of MPA designations. Only 153 of these MPAs have a management plan (MgP) -the basic tool required for an effective management. Amongst these, only 66 are actually managed, i.e. they have the staff and resources required to operate the plan. A common characteristic of these MPAs is the lack of standardized indicators of their performance. In order to address this issue, an alternative approach was developed based on the assessment of management performance using the expert knowledge and perceptions of managers operating MPAs, a universal source of information that could allow overcoming the usual gaps due to the restrictions in coverage of scientific monitoring and assessments. MgPs showed differences among countries but were homogeneous within each country, reflecting the usual top-down approach in the establishment of MPAs. Compliance with the qualitative objectives present in MgPs was higher than compliance with quantitative ones (87% versus 50%), and the MPAs that most successfully achieved their objectives were those with regular monitoring. This analysis also shows that beyond these objectives, the establishment of an MPA and the activities developed as a consequence of its creation have a positive socio-economic impact on the local human community.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242085,"idioma_id":4,"titulo":"DFT study of adsorption and diffusion of atomic hydrogen on metal surfaces","resumen":"An extensive study of adsorption and diffusion of hydrogen atoms on (100) surfaces of fcc Au, Cu, Ag and Pt was performed by means of DFT calculations. Bulk properties of those metals were calculated and compared with previous results. The adsorption distances and energies of the hydrogen atom on top, hollow and bridge sites of the (100) surfaces were calculated in order to elucidate preferential adsorption sites of hydrogen on each metal. All these calculations were done in conjunction with a study of charge distribution. Finally, diffusion of the H &nbsp; atom from the most stable adsorption site to the nearest neighbouring site was studied in order to obtain diffusion barrier and diffusion velocity values. The highest diffusion velocity was found to be v=6.44×1011v=6.44×1011 s&#8722;1 for the case of Ag &nbsp;, whereas the lowest was v=1.13×107v=1.13×107 s&#8722;1 for Au.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242086,"idioma_id":4,"titulo":"Differentiated interactions in phosphate solutions: Comparing Ag(111) and Ag(100) surfaces","resumen":"The electrochemical behavior of phosphate species on Ag(111) and Ag(100) single crystal surfaces was studied by experimental techniques and theoretical calculations. Characteristic cathodic\/anodic potential peaks (Vp) appear in the current density-potential curves (j?V) for H2PO4-, H3PO4, and in the case of PO43- for concentrations lower than 0.1 M, where the interaction is stronger for the Ag(100) electrode. This demonstrate that the adsorption is sensitive to the surface structure. The adsorption energy (Eads) of the different species on both surfaces was studied by means of DFT-vdW calculations. All phosphate species have tri-dentate binding. The |Eads| increased for the H3PO4; H2PO4-; HPO42- and PO43- sequence, and the tetrahedral structures are compressed.Although the same trend was observed on both crystalline surfaces, the films have the symmetry of the substrate, C3v and C4v. The influence of hydroxide co-adsorption was studied for different [HPO42-]\/[PO43-] ratios in solution. The strength of adsorption obtained from experimental and theoretical calculations show an excellent qualitative correlation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242087,"idioma_id":4,"titulo":"CASTE DEVELOPMENTAL PATHWAYS OF Cortaritermes fulviceps (BLATTODEA, TERMITIDAE)","resumen":"The study of the developmental pathways in termites contributes to the understanding of caste evolution and resources utilization, as well as other ecological aspects. In this paper, the caste developmental pathways of Cortaritermes fulviceps (Silvestri) were analyzed in natural colonies from the Province of Corrientes, Argentina. Five measurements were taken of different body parts of larvae (L), workers (W), pre-soldiers (PS), soldiers (S), nymphs (N) and alates (A) for morphometric analyses. Dissections were also performed to determine the sex of workers and soldiers. The collected data were analyzed using principal component analysis, analysis of variance and Tukey test. In the nymphal line, four nymphal instars and alates were identified. The apterous line included two larval instars. Major workers were females and minor workers, presoldiers and soldiers were males. The results suggest that the developmental pathways of C. fulviceps is similar to the one of the genus Nasutitermes Dudley.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242088,"idioma_id":5,"titulo":"Avances para la obtención del mapa de aptitud agrícola en la cuenca del río Luján con evaluación multicriterio.","resumen":"El trabajo presenta avances teóricos-metodológicos para la obtención de un mapadonde se determinen las áreas de aptitud para el desarrollo o la expansión agrícola en la cuenca del río Luján. A partir de las técnicas de Evaluación Multicriterio (EMC) apoyadas en el uso de Sistemas de Información Geográfica (SIG) existen importantes posibilidades para mejorar el proceso de toma de decisiones espaciales, en el marco de una Geografía Aplicada. En este sentido, el trabajo presenta un avance en la aplicación de técnicas de EMC y focaliza en la obtención del mapa de aptitud agrícola que luego será utilizado, junto al mapa de aptitud urbana y aptitud para la conservación, para realizar un modelamiento de la distribución de áreas con potencialidad de conflicto entre usos del suelo en la cuenca.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242090,"idioma_id":5,"titulo":"Identificación de áreas de potencial conflicto entre usos del suelo en la  cuenca del río Luján (Argentina)","resumen":"La Geografía, como ciencia espacial, se apoya en la utilización de métodos cuantitativos aplicados con Sistemas de Información Geográfica (SIG). En este contexto, el modelado cartográfico y las técnicas de evaluación multicriterio permitieron definir una estrategia metodológica para la identificaciónde áreas de potencial conflicto entre usos del suelo en escala regional (LUCIS, Land-use Conflict Identification Strategy). La investigación se realiza en la cuenca del río Luján, con el objetivo de definir estas áreas como consecuencia de la futura competencia espacial entre el uso del suelo urbano, la producción agrícola y las áreas de conservación. Los resultados obtenidos constituyen una excelente herramienta de utilidad en la planificación territorial.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242091,"idioma_id":4,"titulo":"Toxoplasma gondii serine-protease inhibitor-1: a new adjuvant candidate for asthma therapy","resumen":"Serine-proteases are important players inthe pathogenesis of asthma, promoting inflammation and tissue remodeling. It?s alsoknown that many serine protease inhibitors display immunomodulatory properties.TgPI-1 is a Toxoplasma gondii proteinthat exhibits broad spectrum inhibitory activity against serine proteases. Inview of the increased prevalence of atopic disorders and the need to developnew treatment strategies we sought to investigate the potential of TgPI-1 fortreating respiratory allergies. For this purpose, we developed a therapeuticexperimental model. BALB\/c mice were rendered allergic by intraperitonealovalbumin-alum sensitization and airway-challenged. Once the asthmaticphenotype was achieved, mice were intranasally treated with rTgPI-1 alone or witha mixture of rTgPI-1 and ovalbumin (OVA). A week later mice were given asecondary aerosol challenge. Treatment with rTgPI-1 alone or co-administeredwith OVA diminished bronchoalveolar eosinophilia, mucus production and peribronchiallung infiltration. This effect was accompanied by a lung resistance reductionof 26.3% and 50.3% respectively. Both treatments resulted in the production of lowerlevels of IL-4, IL-5, IFN-&#947; and regulatory IL-10 by thoracic lymph nodecells stimulated with OVA. Interestingly, significant decreases in OVA specific IgE and T cellproliferation, and increases in FoxP3+ T cells at local and systemiclevels were only detected when the inhibitor was administered along with OVA. Theseresults show that both rTgPI-1 treatments reduced asthma hallmarks. However,co-administration of the inhibitor with the allergen was more effective. Hence,rTgPI-1 emerges as a noveladjuvantcandidate for asthma treatment","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242095,"idioma_id":5,"titulo":"Miradas docentes sobre los y las jóvenes como ´otros indeseables´ en secundarias universitarias en La Plata","resumen":"En este trabajo presentamos conclusiones de una investigación doctoral enfocándonos en las miradas de docentes de secundarias universitarias en La Plata (Argentina) acerca de los y las jóvenes que las transitan. Se trata de escuelas prestigiosas que modificaron su admisión desde el examen eliminatorio hacia el sorteo  durante el retorno de la democracia a Argentina en la década de 1980. El enfoque metodológico partió de un estudio de caso múltiple: entre 2012 y 2016 realizamos observaciones, entrevistamos 13 actores ?clave?, encuestamos a 67 docentes, analizamos actas del momento de modificación de la admisión e información sociodemográfica de ingresantes. Concluimos que la retórica nostálgica de la educación pasada es atravesada por la añoranza de los ?jóvenes de ayer?: en las miradas de los docentes, la ?decadencia educativa? se imbrica con el desencanto frente a las juventudes actuales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242096,"idioma_id":5,"titulo":"La escolarización en secundarias universitarias en Argentina: la elección escolar entre los techos de cristal y el cierre social","resumen":"En este artículo revisitamos los debates en torno a la elección escolar a partir del caso de un grupo de secundarias universitarias en la capital de la Provincia de Buenos Aires, Argentina. Tras explorar la composición sociocultural de las matrículas de las escuelas, caracterizamos a las familias que asisten y revisitamos las discusiones sobre la elección escolar en relación con procesos de cierre social que persisten más allá de que se trata de secundarias estatales que cuentan con un sorteo público ?abierto? como método de admisión. El enfoque metodológico partió de un estudio de caso múltiple que implicó la combinación de metodologías cuantitativas y cualitativas. Entre los años 2012 y 2016 fueron realizadas observaciones, entrevistados en profundidad trece actores ?clave?, efectuadas sesenta y siete entrevistas semiestructuradas a docentes seleccionados aleatoriamente y recuperado un corpus compuesto por seis documentos institucionales que incluyeron información sociodemográfica de los estudiantes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242097,"idioma_id":5,"titulo":"Métodos de admisión a la educación y concepciones de justicia distributiva: representaciones docentes en una escuela secundaria tradicional","resumen":"En los años ´80 del siglo pasado, en el contexto de retorno de la democracia tras el último Golpe de Estado en Argentina, las escuelas secundarias fueron obligadas a modificar su método de admisión. En el caso de la escuela que abordamos, bajo una retórica igualitarista y democratizante propia de aquel contexto, los exámenes de admisión eliminatorios fueron sustituidos por el sorteo público. En la actualidad existen, sin embargo, concepciones diferenciadas en relación a cuál es el método de admisión considerado más justo para el acceso a esta escuela que, dependiente de una Universidad Nacional, es fuertemente demandada por la población local. En el presente escrito sostenemos que aquellas representaciones sobre la justicia distributiva de las vacantes que se consolidan como hegemónicas reflejan cierta configuración cultural igualitarista imperante en el país según la cual la educación debe ser abierta para todos. De este modo se considera que, al hallarse garantizada la igualdad de oportunidades, quienes consigan triunfar serán efectivamente los más meritorios. Sin embargo, la selección educativa sigue vigente, aunque de un modo sutil o soft.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242100,"idioma_id":4,"titulo":"First records of the minor pest termite Eucryptotermes hagenii (Müller, 1873) (Blattodea, Termitoidae, Kalotermitidae) from native forests of the Chaco biogeographical subregion in Argentina with notes on its morphometry and biology.","resumen":"Eucryptotermes Holmgren, 1911 comprises two species of neotropical drywood termites with phragmotic head soldiers. We report the presence of E. hagenii (Müller, 1873) in native forests of the Chaco biogeographical subregion, enlarging its distribution and recording the genus and species for the first time in Argentina. E. hagenii abundance was estimated as intermediate by standardized sampling. Eighteen morphometric characters were measured in soldiers and alates and nine of them provided new data. The colonies, located inside living trees trunks and dead wood, were composed of reproductives, soldiers, pseudergates andimmatures.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242101,"idioma_id":5,"titulo":"Las matrices operatorias del significado absoluto","resumen":" Las matrices operatorias del significado absoluto, Centeno de de Hoyos, R. En Las fronteras del presente filosófico, Rev. Logos e Historia Vol.6, 2016-2017.Liliana Mannina de Gamero Edit.Fac.de Fil.y letras, UNCuyo. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242102,"idioma_id":5,"titulo":"¿La percepción está determinada por conceptos?","resumen":"Como respuesta a algunas críticas en torno de una versión inicial de suconceptualismo del contenido empírico (McDowell, J., 1994, 1998, 2005) John McDowell (en McDowell, J., 2008, 2011) reconsidera dos tesis centrales de su Empirismo Mínimo (EM): I) la experiencia tiene una estructura proposicional; II) el contenido debe incluir todo lo que la experiencia le permite al sujeto conocer no-inferencialmente. La revisión de ambas tesis lo lleva a concluir que la experiencia cuenta con un ?contenido intuicional? de carácter conceptual pero no proposicional. Nuestro trabajo se centra sobre esta noción y tiene un doble objetivo: 1) situar las ventajas explicativas de dicho concepto; 2) señalar la dificultad de la distinción entre un nivel de conceptualización básico y otro nivel correspondiente a capacidades que no se actualizarían en la experiencia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242103,"idioma_id":5,"titulo":"Regulación de carga frutal en cerezo Royal Dawn: efecto en el rendimiento,  crecimiento vegetativo y calidad de la fruta","resumen":"El objetivo del trabajo fue caracterizar el comportamiento productivo y evaluar el efecto de la regulación de la carga frutal sobre el rendimiento, el crecimiento de brotes y la calidad de la fruta en la cv. de cerezo Royal Dawn, en la provincia de Mendoza, Argentina, en una plantación de 4 años de edad al inicio de los ensayos. El primer año se estudió el comportamiento productivo sin manejo de la carga. En el segundo año los tratamientos fueron: Poda (eliminación del 35 % de madera frutal, P); Poda + extinción del 30 % de los ramilletes (P+E30%); Poda + extinción del 50% de los ramilletes (P+E50%) y Extinción del 30% de los ramilletes (E30%). El tercer año se midió la longitud los brotes en cada tratamiento. En el año 1 el rendimiento fue muy alto aunque el 99,86% de la fruta tuvo un tamaño no exportable &#8804; 24mm. En P+E30% y P+E50 % se redujeron marcadamente los rendimientos en relación a P y a E30%. La regulación mejoró la distribución de calibres y aumentó la proporción de frutos >24 mm. En  P+E30% y P+E50% disminuyó a niveles muy bajos la fruta &#8804;24 mm, y además en P+E50%  aumentó la cantidad de cerezas >28mm. En el tratamiento de menor carga hubo mayor crecimiento de brotes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242104,"idioma_id":4,"titulo":"Assessing wildfire exposure in the Wildland-Urban Interface area of the mountains of central Argentina","resumen":"Wildfires are a major threat to people and property in Wildland Urban Interface (WUI) communities worldwide, but while the patterns of the WUI in North America, Europe and Oceania have been studied before, this is not the case in Latin America. Our goals were to a) map WUI areas in central Argentina, and b) assess wildfire exposure for WUI communities in relation to historic fires, with special emphasis on large fires and estimated burn probability based on an empirical model. We mapped the WUI in the mountains of central Argentina (810,000 ha), after digitizing the location of 276,700 buildings and deriving vegetation maps from satellite imagery. The areas where houses and wildland vegetation intermingle were classified as Intermix WUI (housing density > 6.17 hu\/km2 and wildland vegetation cover > 50 %), and the areas where wildland vegetation abuts settlements were classified as Interface WUI (housing density > 6.17 hu\/km2, wildland vegetation cover < 50 %, but within 600 m of a vegetated patch larger than 5 km2). We generated burn probability maps based on historical fire data from 1999 to 2011; as well as from an empirical model of fire frequency. WUI areas occupied 15 % of our study area and contained 144,000 buildings (52%). Most WUI area was Intermix WUI, but most WUI buildings were in the Interface WUI. Our findings suggest that central Argentina has a WUI fire problem. WUI areas included most of the buildings exposed to wildfires and most of the buildings located in areas of higher burn probability. Our findings can help focus fire management activities in areas of higher risk, and ultimately provide support for landscape management and planning aimed at reducing wildfire risk in WUI communities.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242108,"idioma_id":5,"titulo":"Las experiencias de las artistas del colectivo Minas de Arte: prácticas heréticas en el campo artístico mendocino durante los noventa. Una lectura desde la teoría feminista","resumen":"El presente artículo tiene por objeto presentar una lectura, desde la perspectiva de género\/feminista, en torno a las prácticas del colectivo Minas de Arte (Mendoza, 1993-1997), a partir de los relatos de las experiencias de las artistas que integraron el grupo. Para acceder a sus testimonios hemos realizado una serie entrevistas, a través de las cuales buscamos indagar en torno a las significaciones que las artistas les otorgan, desde el presente, a: sus condiciones de producción, las prácticas que llevaron a cabo, la recepción de su trabajo y el lugar que ocuparon en el campo artístico de la provincia de Mendoza.Partimos del supuesto que algunas de las prácticas que llevó a cabo este colectivo pueden considerarse como heréticas (Bourdieu, 1990) para el campo artístico local de la década del noventa.Los testimonios de las artistas, así como el abordaje de material documental sobre el grupo, nos han permitido identificar en su obra ciertas transgresiones respecto a normas o prácticas vigentes en el contexto local. Concluimos, asimismo, que algunas de sus producciones pueden considerarse como expresiones de arte de género y que es posible identificar en ellas un feminismo involuntario (Bartra, 1994).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242109,"idioma_id":4,"titulo":"Spatial population dynamics and temporal analysis of the distribution of Lutzomyia longipalpis (Lutz &amp; Neiva, 1912) (Diptera: Psychodidae: Phlebotominae) in the city of Clorinda, Formosa, Argentina","resumen":"Background: Lutzomyia longipalpis, the vector for the causal agent of visceral leishmaniasis (VL), has extended its distribution in the southern cone in the Americas. The first urban record of Lu. longipalpis in Argentina was from the City of Clorinda in 2004. The aim of this study was to analyse the monthly distribution and abundance of Lu. longipalpis and to evaluate its association with environmental and climatic variables in Clorinda City, Province of Formosa. Methods: Phlebotominae sampling was performed using CDC light mini-traps that were placed in different sites of the city between January 2012 and December 2013. Environmental variables including the normalised difference vegetation index, normalized difference water index, land surface temperature and precipitation were evaluated using a spatiotemporal model. Results: A total of 4996 phlebotomine sandflies were captured during the study period, and eight species were reported: Lu. longipalpis, Migonemyia migonei, Nyssomyia whitmani, Ny. neivai, Brumptomyia guimaraesi, Evandromyia cortelezzii\/sallesi, Psathyromyia bigeniculata and Expapillata firmatoi. This is the first urban record of Ex. firmatoi in Argentina. Lutzomyia longipalpis was the most abundant species between 2012 and 2013, and it appeared in all the sampled sites. Moreover, the model applied showed that ground humidity and temperature were significantly associated with the abundance of Lu. longipalpis. Conclusions: This longitudinal approach at city scale allows for modelling that explains more than 60% of the temporal variability of the abundance of Lu. longipalpis based exclusively on satellite obtained data. The results support the hypothesis of steady ´hot spots´ of abundance with time, while other sites could change its abundance due to eventual microenvironment changes. The Lu. longipalpis abundance driving factors are breeding site-related variables, highlighting the importance both for modelling and surveillance to use lag data.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242110,"idioma_id":4,"titulo":"Analytical report of the 2016 Dengue outbreak in Córdoba city (Argentina)","resumen":"After elimination of the Aedes aegypti vector in South America in the 1960s, dengue outbreaks started to reoccur during the 1990s; strongly in Argentina since 1998. In 2016, Córdoba City had the largest dengue outbreak in its history. In this article we report this outbreak including spatio-temporal analysis of cases and vectors in the city. A total of 653 dengue cases were recorded by the laboratory-based dengue surveillance system and georeferenced by their residential addresses. Case maps were generated from the epidemiological week 1 (beginning of January) to week 19 (mid-May). Dengue outbreak temporal evolution was analysed globally and three specific, high-incidence zones were detected using Knox analysis to characterising its spatio-temporal attributes. Field and remotely sensed data were collected and analysed in real time and a vector presence map based on the MaxEnt approach was generated to define hotspots, towards which the pesticide-based strategy was then targeted. The recorded pattern of cases evolution within the community suggests that dengue control measures should be improved.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242111,"idioma_id":5,"titulo":"Estilos de Crianza parental. Una revisión teórica.","resumen":"Objetivo: analizar las perspectivas actuales en el estudio de los estilos parentales de crianza y las variables relacionadas a estos. Método: se realizó una revisión sistemática de la bibliografía al respecto. Para ello, se seleccionaron artículos publicados en revistas científicas de psicología que están indexadas en bases de datos electrónicas, mediante la adopción de criterios predeterminados. Se incluyeron textos que fueran artículos de revisión, reportes de investigación y estudios psicométricos con los instrumentos de evaluación de la variable en estudio. Resultados: las categorías identificadas, analizadas y teorizadas, fueron: Abordajes en el estudio de los estilos parentales, Categorías de los estilos de crianza, Estilos de crianza y tipos de familias, Estilos de crianza y relaciones con otras variables, y Perspectivas en el estudio de los estilos educativos parentales. Conclusiones: en esta revisión teórica se identificaron cinco categorías de análisis esenciales para la comprensión del tema en estudio.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242112,"idioma_id":4,"titulo":"In-Situ and Satellite Monitoring of Water Quality of an Eutrophic Lake with an Artificial Air Diffusion System","resumen":"Wildfires are a major threat to people and property in Wildland Urban Interface (WUI) communitiesworldwide, but while the patterns of the WUI in North America, Europe and Oceania have been studiedbefore, this is not the case in Latin America. Our goals were to a) map WUI areas in central Argentina, andb) assess wildfire exposure for WUI communities in relation to historic fires, with special emphasis onlarge fires and estimated burn probability based on an empirical model. We mapped the WUI in themountains of central Argentina (810,000 ha), after digitizing the location of 276,700 buildings andderiving vegetation maps from satellite imagery. The areas where houses and wildland vegetationintermingle were classified as Intermix WUI (housing density > 6.17 hu\/km2 and wildland vegetationcover > 50%), and the areas where wildland vegetation abuts settlements were classified as InterfaceWUI (housing density > 6.17 hu\/km2, wildland vegetation cover < 50%, but within 600 m of a vegetatedpatch larger than 5 km2). We generated burn probability maps based on historical fire data from 1999 to2011; as well as from an empirical model of fire frequency. WUI areas occupied 15% of our study area andcontained 144,000 buildings (52%). Most WUI area was Intermix WUI, but most WUI buildings were inthe Interface WUI. Our findings suggest that central Argentina has a WUI fire problem. WUI areasincluded most of the buildings exposed to wildfires and most of the buildings located in areas of higherburn probability. Our findings can help focus fire management activities in areas of higher risk, andultimately provide support for landscape management and planning aimed at reducing wildfire risk inWUI communities.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242113,"idioma_id":4,"titulo":"Changes in the structure of Melolonthidae (Coleoptera: Scarabaeoidea) assemblages along a temporal gradient in a Natural Reserve in Chaco, Argentina","resumen":"Melolonthidae beetles have been proposed as bioindicators because of their important role in the ecosystem and sensitivity to disturbance processes. However, the assemblage structure of these species in Argentina is unknown. In this study, the first attempt at determining Melolonthidae diversity, we analysed the abundance and diversity of the Melolonthidae assemblage and the species richness turnover over a period of three years. We collected samples in a gallery forest relict of a small protected area in which two light traps were installed. We collected a total of 474 specimens belonging to 38 species, two of which are new records for Argentina. The assemblage was characterized by numerous rare species, and the richness and diversity as well as the distribution of species abundance varied over the three years of the study. Replacement values varied based on the similarity indices that were used. Selected environmental variables (relative humidity, temperature and rainfall) were correlated with the richness and the abundance of the beetles. Our results suggest that the community of Melolonthidae could be considered dynamic, even over relatively short periods of time. Rare species play a major role in analyses of the similarity between assemblages and could suggest exaggerated turnover values. The high richness of the study area may be due to its good state of preservation or to its small area, which allows the entry of species from surrounding environments, showing how complex and fluid the Melolonthidae community can be in small patches of forest","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242114,"idioma_id":4,"titulo":"Description of the pupa and redescription of the third instar of Phileurus valgus (Olivier) (Coleoptera: Scarabaeidae: Dynastinae: Phileurini)","resumen":"Phileurus valgus (Olivier) (Coleoptera: Scarabaeidae: Dynastinae: Phileurini) is a common species widely distributed from the southern United States to Argentina and the West Indies. In this work the immature stages are described and illustrated based on specimens from Argentina. A key to the known third-stage larvae of New World Phileurini species is provided and updated. Notes on the life cycle and natural history are also included.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242119,"idioma_id":4,"titulo":"Immediate type and delayed type skin testing with a Helicobacter pylori (Hp) extract in atopic and non-atopic patients","resumen":"No disponible","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242120,"idioma_id":4,"titulo":"Immunochemical and immunopathological actions of the fungus Bipolaris australiensis in animals and in humans","resumen":"No disponible","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242122,"idioma_id":5,"titulo":"Prevalencia del s&iacute;ndrome de burnout en residentes de Pediatr&iacute;a de un hospital","resumen":"Introducción: La residencia médica es una etapa de gran estrés; pudiendo contribuir a la aparición del síndrome de burnout (SBO) y depresión. No obstante, a pesar de la importancia de este síndrome para la salud del profesional y de pacientes, ha sido poco estudiado en residentes dePediatría.Objetivo: Describir la prevalencia del SBO en médicos residentes de Pediatría de un hospital.Método: Estudio descriptivo, transversal. Se aplicó en forma anónima, voluntaria, el cuestionario de Maslach Burnout Inventory a residentes de Pediatría del hospital pediátrico referente. Las variables analizadas fueron: sexo, edad, estado civil, ano? de la residencia, SBO. Los datosobtenidos fueron procesados mediante programa SPSS (v.13.0).Resultados: Quedaron incluidos 18 residentes de los cuales 4 fueron (R1); 6 (R2) y 8 (R3). Del total 14 fueron mujeres y 4 hombres, con un rango de 25 a 32 anos ? (edad media: 28 anos). ? La tasa de respuesta fue del 100%, hallándose SBO en el 100% de los residentes. Los valores obtenidos de las subescalas fueron de 18 residentes: 9 con alto cansancio emocional (CE); 12 con alta despersonalización (DP) y 11 con baja realización personal (RP). Del análisis del cuestionario deMaslach Burnout Inventory se desprende que de 4 (R1) se halló: 3 con bajo CE; 2 con baja DP y Prevalencia y caracterización del síndrome de burnout en residentes 161 4 con baja RP. En tanto que de 6 (R2): 4 presentaron baja RP y 3 tuvieron entre alto y moderado CE y DP. Mientras que de 8 (R3): todos presentaron alta DP y 5 con alto CE y 3 con bajo RP. Se halló que el SBO en todos los casos fue moderado.Conclusiones: Todos los residentes de la especialidad de Clínica Pediátrica de este hospital presentaron valores compatibles con SBO, siendo el componente más afectado la alta DP.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242125,"idioma_id":4,"titulo":"Boron neutron capture therapy (BNCT) translational studies in the hamster cheek pouch model of oral cancer at the new &ldquo;B2&rdquo; configuration of the RA-6 nuclear reactor","resumen":"Boron neutron capture therapy (BNCT) is based on selective accumulation of B-10 carriers in tumor followed by neutron irradiation. We demonstrated, in 2001, the therapeutic effect of BNCT mediated by BPA (boronophenylalanine) in the hamster cheek pouch model of oral cancer, at the RA-6 nuclear reactor. Between 2007 and 2011, the RA-6 was upgraded, leading to an improvement in the performance of the BNCT beam (B2 configuration). Our aim was to evaluate BPA-BNCT radiotoxicity and tumor control in the hamster cheek pouch model of oral cancer at the new ?B2? configuration. We also evaluated, for the first time in the oral cancer model, the radioprotective effect of histamine against mucositis in precancerous tissue as the dose-limiting tissue. Cancerized pouches were exposed to: BPA-BNCT; BPA-BNCT + histamine; BO: Beam only; BO + histamine; CONTROL: cancerized, no-treatment. BNCT induced severe mucositis, with an incidence that was slightly higher than in ?B1? experiments (86 vs 67%, respectively). BO induced low\/moderate mucositis. Histamine slightly reduced the incidence of severe mucositis induced by BPA-BNCT (75 vs 86%) and prevented mucositis altogether in BO animals. Tumor overall response was significantly higher in BNCT (94?96%) than in control (16%) and BO groups (9?38%), and did not differ significantly from the ?B1? results (91%). Histamine did not compromise BNCT therapeutic efficacy. BNCT radiotoxicity and therapeutic effect at the B1 and B2 configurations of RA-6 were consistent. Histamine slightly reduced mucositis in precancerous tissue even in this overly aggressive oral cancer model, without compromising tumor control.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242127,"idioma_id":4,"titulo":"Barcoding the butterflies of southern South America: species delimitation efficacy, cryptic diversity and geographic patterns of divergence","resumen":"Because the tropical regions of America harbor the highest concentration of butterfly species, its fauna has attracted considerable attention. Much less is known about the butterflies of southern South America, particularly Argentina, where over 1,200 species occur. To advance understanding of this fauna, we assembled a DNA barcode reference library for 417 butterfly species of Argentina, focusing on the Atlantic Forest, a biodiversity hotspot. We tested the efficacy of this library for specimen identification, used it to assess the frequency of cryptic species, and examined geographic patterns of genetic variation, making this study the first large-scale genetic assessment of the butterflies of southern South America. The average sequence divergence to the nearest neighbor (i.e. minimum interspecific distance) was 6.91%, ten times larger than the mean distance to the furthest conspecific (0.69%), with a clear barcode gap present in all but four of the species represented by two or more specimens. As a consequence, the DNA barcode library was extremely effective in the discrimination of these species, allowing a correct identification in more than 95% of the cases. Singletons (i.e. species represented by a single sequence) were also distinguishable in the gene trees since they all had unique DNA barcodes, divergent from those of the closestnon-conspecific. The clustering algorithms implemented recognized from 416 to 444 barcode clusters, suggesting that the actual diversity of butterflies in Argentina is 3%±9% higher than currently recognized. Furthermore, our survey added three new records of butterflies for the country (Eurema agave, Mithras hannelore, Melanis hillapana). In summary,this study not only supported the utility of DNA barcoding for the identification of the butterfly species of Argentina, but also highlighted several cases of both deep intraspecific and shallow interspecific divergence that should be studied in more detail.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242129,"idioma_id":1,"titulo":"Geomatic Applications in Earth Sciences","resumen":"Editor de libro con 13 trabajos relacionados a la utilización de la teledetecciñón y los Sistemas de Información geográfica en las Ciencias de la Tierra. Con contribuciones de investigadores latinoamericanos de Argentina, Chile, Colombia, Venezuela, Brasil y Cuba. Publicado como número especial de la revista.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242130,"idioma_id":5,"titulo":"Introducción al dossier: Cultura, medios y sociedad en América Latina entre el siglo XX y el XXI","resumen":"El dossier ?Cultura, medios y sociedad en América Latina entre el siglo XX y el XXI? reúne una serie de comentarios críticos sobre libros de reciente publicación que abordan las relaciones entre las producciones culturales, los medios de comunicación y las sociedades en la historia contemporánea de América Latina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242138,"idioma_id":5,"titulo":"Periodontitis agresiva, caracteristicas, diagnostico y tratamiento","resumen":"La periodontitis agresiva es una afección periodontal grave, de aparición temprana, poco frecuente, que presenta características clínicas específicas como criterios de diagnóstico. Su etiopatogenia establece que causa gran destrucción de tejido periodontal en un periodo de tiempo relativamente breve, lo que implica una infección por patógenos altamente virulentos y un nivel alto de susceptibilidad del huésped a la enfermedad, dando lugar a una expresión clínica que progresa con rapidez. Su diagnóstico requiere enfocar una minuciosa anamnesis en la historia médica y un meticuloso examen clínico periodontal para detectar los criterios que determinan su diagnóstico. El tratamiento depende del diagnóstico temprano, la orientación del tratamiento hacia la eliminación de los microorganismos infectantes y la creación de un ambiente que promueva el mantenimiento a largo plazo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242139,"idioma_id":5,"titulo":"Investigacion cientifica y vulnerabilidad humana","resumen":"La vulnerabilidad es una caracteristica de la persona humana. Somos fragiles, mortales. Somos vulnerables. Sin investigacion cientifica no hay progreso posible. La investigacion cientifica con personas necesita cumplir y hacer cumplir las normativas internacionales para tal fin. La participacion de personas en investigacion implica tener presente el respeto a su dignidad y su condicion de fragilidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242142,"idioma_id":5,"titulo":"El puño silenciador","resumen":"Las escenas de cientos de voluntarios arrojados a las calles tras el terremoto que castigó impiadoso a México el 19 de septiembre pasado se repiten desde entonces y muestra que la ciudadanía siempre está un paso más adelante.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242146,"idioma_id":5,"titulo":"EVALUACIÓN DE LA NUEVA DEFINICIÓN DE POLITRAUMA EN UNA COHORTE DE PACIENTES DE 10 HOSPITALES ARGENTINOS","resumen":"La definición de Berlin de politrauma (2014) combina la severidad lesional con al menos uno de cinco complementos (edad, TAS, GCS, KPTT o EB). Hasta ahora hay insuficiente información sobre cómo afecta esta nueva definición la identificación de los grupos con mayor mortalidad. El objetivo de este trabajo fue evaluar la performance de esta definición comparándola con otras mediciones. Métodos Análisis retrospectivo observacional de ingresos prospectivos al Registro de Trauma de Fundación Trauma en 10 hospitales entre 2010-2016. Los criterios de inclusión fueron edad > 15 años y tener información completa para el cálculo de los índices. Los pacientes se compararon según las definiciones de politrauma (PT), trauma múltiple (Tmult), trauma mayor por ISS (TM_ISS) y trauma mayor por NISS (TM_NISS). Se analizaron medidas de performance. Resultados Se analizaron 259 hechos con PT, 802 con Tmult, 1349 con TM_ISS y 2143 con TM_NISS. El grupo PT resultó heterogéneo, con una mortalidad entre 44% y 71% según diferentes combinaciones de complementos. El 75% tuvo lesiones por transporte y el 76% tuvo al menos una lesión encefálica AIS>2. El desenlace estuvo relacionado con el estado al ingreso, por impacto fisiológico (RTS) y por severidad lesional (ISS-NISS). La relación O\/E para sobrevida por TRISS fue 0.73. La comparación con las otras definiciones mostró diferencias estadísticamente significativas en mortalidad pero no en ISS, NISS ni RTS. La evaluación de performance mostró que TM_NISS tuvo la mayor sensibilidad y el mayor VPN, mientras que PT tuvo el mayor VPP. Como medida global, TM_ISS tuvo una precisión superior al resto (89%) y una especificidad de 97%. Conclusiones La definición de PT para identificación de pacientes con mayor riesgo de muerte no mostró ser superior a otras definiciones de uso corriente. Consideramos que la definición de PT necesita ser validada en estudios multicéntricos antes de recomendarse como un nuevo standard.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242147,"idioma_id":4,"titulo":"Asociaciones macrobent&oacute;nicas con presencia de mit&iacute;lidos de la bah&iacute;a San Juli&aacute;n (Patagonia austral, Argentina)","resumen":"Las asociaciones de macrobentos con presencia de mitílidos de la bahía San Julián (Patagonia austral, Argentina) fueron muestreadas durante el verano de 2007 para conocer su estructura, diversidad y distribución, y para determinar su relación con diversos factores ambientales. El estudio fue realizado en 3 localidades con diferentes tipos de sustrato y distinta pendiente. El muestreo en cada localidad se realizó en una transecta abarcando diferentes niveles del intermareal y del submareal somero. Se hallaron un total de 46 especies pertenecientes principalmente a moluscos (20), crustáceos (12) y poliquetos (10). Se identificaron 3 asociaciones principales: la asociación Platynereis-Clunio-Darina se distribuyó en el nivel intermareal superior de sustrato fangoso y pendientes suaves y presentó los valores más bajos de número de especies, de diversidad específica y de abundancia de individuos; la asociación Mytilus-Perumytilus se distribuyó en los niveles intermareales medio e inferior en sustrato rocoso o en sustrato fangoso con abundantes elementos de soporte y pendiente media; presentó diversidad específica intermedia y la mayor abundancia de individuos; la asociación Aulacomya-Exosphaeroma presentó el mayor número de especies y la mayor diversidad, pero baja abundancia de individuos, encontrándose relacionado a sustratos rocosos o sustratos fangosos con elementos de soporte y baja pendiente del submareal superior. La riqueza específica y la diversidad de estas asociaciones aumentan desde el nivel superior del intermareal hacia el submareal, posiblemente por efecto de un gradiente complejo de estrés, principalmente ocasionado por la desecación y exposición a temperaturas extremas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242151,"idioma_id":5,"titulo":"Walsh: escritura y verdad en cada momento histórico","resumen":"En el artículo se pone en diálogo la trayectoria vital de Rodolfo Walsh con los momentos históricos, sociales y políticos de la Argentina, entre 1930 y 1976. El trabajo caracteriza cada momento históricosocial y, a partir de la diversidad de sus escritos literarios y periodísticos, indica los cambios en la perspectiva política de Walsh a lo largo de su vida, desde posicionamientos cercanos al nacionalismo de derechas antiperonistas, hasta su militancia e inclusión en el Peronismo Revolucionario. El autor señala que este tránsito y sus modificaciones se desarrollan, particularmente, a partir de su obra periodística y literaria y desde allí hacia la militancia política.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242157,"idioma_id":4,"titulo":"Participant recruitment and retention in longitudinal preconception randomized trials: lessons learnt from the calcium and pre-eclampsia (CAP) trial","resumen":"BackgroundThe preconception period has the potential to influence pregnancy outcomes and randomized controlled trials (RCTs) are needed to evaluate a variety of potentially beneficial preconception interventions. However, RCTs commencing before pregnancy have significant participant recruitment and retention challenges. The calcium and pre-eclampsia trial (CAP trial) is a World Health Organization multi-country RCT of calcium supplementation commenced before pregnancy to prevent recurrent pre-eclampsia in which non-pregnant participants are recruited and followed up until childbirth. This sub-study explores recruitment methods and pre-conception retention of participants of the CAP trial to inform future trials.MethodsRecruiters at the study sites in Argentina, South Africa and Zimbabwe completed post-recruitment phase questionnaires on recruitment methods used. Qualitative data from these questionnaires and quantitative data on pre-pregnancy trial visit attendance and pregnancy rates up to August 2016 are reported in this paper. RStudio (Version 0.99.903 https:\/\/www.rstudio.org) statistical software was used for summary statistics. ResultsBetween July 2011 and August 2016, 1354 women with previous pre-eclampsia were recruited. Recruitment took two years longer than expected and was facilitated mainly through medical record\/register and maternity ward\/clinic-based strategies. Recruiters highlighted difficulties associated with inadequate medical records, redundant patient contact details, and follow-up of temporarily ineligible women as some of the challenges faced. Whilst the attendance rates at pre-pregnancy visits were high (78% or more), visits often occurred later than scheduled. Forty-five percent of participants became pregnant (614\/1354), 33.5% (454\/1354) within one year of randomization. ConclusionsIn preconception trials, both retrospective and prospective methods are useful for recruiting eligible women with certain conditions. However, these are time-consuming in low-resource settings with suboptimal medical records and other challenges. Trial planners should ensure that trial budgets cover sufficient on-site researchers with pre-trial training, and should consider using mobile phone and web-based electronic tools, to optimize recruitment and retention. This should lead to greater efficiency and shorter trial durations.Trial registration The trial was registered with the Pan-African Clinical Trials Registry on December 6, 2010 (Registration Number: PACTR201105000267371).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242158,"idioma_id":4,"titulo":"Geometry and kinematics of the Fuegian thrust-fold belt, southernmost Andes","resumen":"Published balanced structural interpretations of the Fuegian thrust-fold belt (southernmost Andes) fail to address aspects such as basement shortening in the thrust-fold belt, or its structural connection with the central belt of the orogen. We tackle this deficiency by constructing four serial balanced cross-sections based on surface geologic information, 2D reflection seismic lines, and well logs, which depict the first-order structural geometry and kinematics from the thrust front to the internal thrust-fold belt. The interpretation reveals three main tectonostratigraphic packages separated by major detachments: basement (Paleozoic-Upper Jurassic), Cretaceous, and Paleogene, all variably involved in thrusting along strike. Minimum shortening in the Paleogene cover ranges between 16% and 43%, and significant style changes are observed across and along the thrust wedge. We show that basement thrust-sheets have a major role in the construction of the thrust-fold belt; some of them were emplaced below the thrust front during late Oligocene or early Miocene times. The kinematic evolution of the thrust-fold belt indicates that the active detachments depended on the existence of high pore pressure to propagate forward. Our model shows that this pore pressure buildup was controlled by overburden, mean rock impermeability, and strain-rate; the variable interaction among these factors controlled the propagation and style of the thrust-wedge.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242159,"idioma_id":4,"titulo":"Spatial and temporal characterization of progressive deformation during orogenic growth: example from the Fuegian Andes, southern Argentina","resumen":"Superposed structural fabrics in the easternmost Fuegian Andesreveal two distinct, non-coaxial deformation phases across the transitionfrom the orogenic core to the thrust-fold belt. Each phase ischaracterized by different metamorphic conditions and consistentlydifferent orientations, which allow the structural correlation betweenthe orogenic core and the internal thrust-fold belt. The firstdeformation phase was coeval with regional metamorphism reaching uppergreenschist facies, and featured simple shear deformation of the basement(Paleozoic and Jurassic) and cover (Cretaceous) in the top of theunderthrusting South American plate. The second phase developed duringcollision of the orogenic wedge with the Río Chico Arch, a promontory inthe underthrusting plate; this phase was characterized by thrust sheetemplacement and formation of a crustal duplex, with rock uplift andconsequent low to very-low grade metamorphism. Buttressing against theRío Chico Arch is responsible for the change in shortening orientationthat distinguishes both phases.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242160,"idioma_id":4,"titulo":"Development and proliferation of feline endometrial glands from fetal life to ovarian cyclicity","resumen":"In this study it was determined the progression of uterine gland development from late gestation to puberty in domestic felids. Cell proliferation patterns for luminal (LE), glandular epithelium (GE) as well as stroma (S) were also described. Twenty-four uteri from female kittens: 45 and 65 days of gestation and 1 to 5, 8, 12, 16, 20 and 24 weeks postnatally were obtained. Uterine cross-sections were submitted for routine histological and immunohistochemical quantification of proliferating cell nuclear antigen (PCNA) techniques. Although prenatal uteri presented no indication of adenogenesis, 1 week old uteri revealed an incipient budding of the LE. During the second week budding increased and a mild degree of tubulogenesis of the GE into the stroma was detected. From the third to fifth weeks coiling, branching and cross-sections of glands appeared. These latter findings were more evident in week 8 when GE began to penetrate through much of the S to week 24. PCNA immunostaining revealed that DNA synthesis decreased throughout the study in the 3 cell compartments; (P < 0.01). Luminal proliferation began prenatally, it maintained up to postnatal week 8 to markedly decrease to puberty (P < 0.01). From postnatal week 3 up to week 8, GE mitotic activity was elevated becoming low thereafter (P < 0.01). Stroma actively proliferated prenatally (P < 0.01), diminishing up to week 8 (P < 0.01) and again during the last weeks (P < 0.01) of the study. It was concluded that, in domestic felids, proliferation of LE begins prenatally, histological uterine adenogenesis commenced during the first postnatal week and both events concluded by postnatal weeks 5?8.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242161,"idioma_id":5,"titulo":"Mujeres que ejercen prostitución en Río Gallegos. Una propuesta desde el análisis cultural","resumen":"Desde la propuesta del análisis cultural y tomando la discusión sobre los procesoshegemónicos, el artículo se centra en el debate por la prostitución comoexplotación o como trabajo a raíz de la llegada del auge abolicionista a travésde su forma jurídico política en el año 2008. Nos enfocamos en los saberes yprácticas que están en pugna en Río Gallegos, al sur de la Argentina, con focoen los procesos de negociación en los que participan las mujeres que ejercenprostitución. Las preguntas finales se relacionan con las condiciones para la organizacióncolectiva de las mujeres que ejercen prostitución y con cómo se vivela subalternidad en un enclave sureño periférico del contexto nacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242165,"idioma_id":5,"titulo":"Estrategias para la gestión del conocimiento en ambientes mediados, caso de aplicación en la industria petrolera","resumen":"Los avances de las tecnologías de la información y lacomunicación, propician un contexto de cambios en la llamadasociedad de la información y el conocimiento, este es un factorclave para determinar seguridad, prosperidad y calidad de vida.Otro aspecto a considerar es el grado con el que la colaboracióninformal (sobre todo a través de redes) entre individuos einstituciones está reemplazando a estructuras sociales másformales en corporaciones, universidades y gobiernos.En el ámbito de las organizaciones, podemos identificar el usode nociones como: aprendizaje organizacional, que sueleasociarse a la capacidad de una organización para ser flexibley ágil en la gestión de solución de problemas o, incluso, a lacapacidad de innovación y creación que la mismaorganización puede alcanzar, bajo la utilización de lasTecnologías de la Información y Comunicación.Para lograr este objetivo las organizaciones necesitan formas deadministrar y mantener el registro del aprendizaje de losempleados, para integrarlo de una forma más completa a sussistemas de administración del conocimiento, utilizandoherramientas como los sistemas de administración delaprendizaje, learning management system, que proveenherramientas para administrar, ofrecer, rastrear y evaluar losdiversos tipos de aprendizaje y capacitación para losempleados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242169,"idioma_id":5,"titulo":"Vulnerabilidad al cambio climático: Dificultades en el uso de indicadores en dos cuencas de Colombia y Argentina","resumen":"Este artículo evidencia las dificultades metodológicas y teóricas en el uso deIndicadores sociales para evaluar la vulnerabilidad al cambio climático y de estaforma contribuye a refinar las estrategias metodológicas para el abordaje de estefenómeno. La mayoría de los estudios de vulnerabilidad al cambio climático ladefinen como una expresión de tres dimensiones: la exposición de los sistemas alos fenómenos climáticos, la sensibilidad a esas condiciones riesgosas, y su capacidadpara afrontar los impactos que los afectan. Estas tres dimensiones facilitanla operacionalización del concepto a partir de indicadores biofísicos y socialescuya principal finalidad es cuantificar el fenómeno y establecer relaciones de causalidad entre eventos y recursos. Frente a esta conceptualización, otra manerade entender el fenónemo es definirla como un proceso dinámico determinadoprocesos sociales, económicos, políticos, culturales e institucionales. Desdeeste enfoque el cambio climático impacta sobre una serie de vulnerabilidadesprevias y de largo plazo definidas principalmente por el acceso a los recursos.La vulnerabilidad se define entonces, como un proceso cuya complejidad noadmite cuantificaciones ni generalizaciones entre causas y efectos como las queproponen los sistemas de indicadores. A partir de una experiencia de investigaciónconcreta en las cuencas de los ríos Mendoza, en Argentina, y Chinchiná,en Colombia este artículo demuestra las limitaciones que el uso de indicadoresde vulnerabilidad social conllevan para la investigación social aplicada. Conbase en el análisis de datos estadísticos de uso público disponible en Argentinay en Colombia y de entrevistas en profundidad en las areas de estudio, los autoresreconstruyen las dificultades enfrentadas al momento de construir dichosindicadores para demostrar las debilidades de cada indicador para dar cuenta delcomplejo fenómeno de la vulnerabilidad. Se analizan en particular los indicadoresde nivel de ingresos, tenencia de la tierra, acceso al agua, infraestructuratecnológica, asistencia técnica, asociativismo y nivel educativo. Para finalizar, sepresenta una propuesta alternativa para dar cuenta de las complejidades propiasdel fenómeno de la vulnerabilidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242171,"idioma_id":5,"titulo":"El acuario de-clara","resumen":"Este ensayo busca compartir debates, contradicciones e interrogantes que nos generó el film Aquarius, a partir de nuestras trayectorias y experiencias como trabajadoras del sistema público de salud. Desde la construcción interdisciplinaria, reflexionamos sobre temáticas y conceptos como género, clase social, etnia, raza, identidad\/ alteridad, lógicas y subjetividades de época, gentrificación. El resultado fue la apertura de preguntas e interpretaciones diversas de las historias que se entrecruzan en una compleja trama a partir de la figura de Clara, la protagonista. Utilizamos tres niveles de análisis, vinculados y jerarquizados: un nivel macro, vinculado a la lógica mercantil y al modo de producción, otro referido a las relaciones sociales (institucional) y, el último, de vida cotidiana (particularización de lo genérico social, encarnado en el relato de situaciones del film). El desafío fue problematizar lecturas obvias y desde allí cuestionar nuestros propios mandatos en torno a lo femenino y la mujer. Proponemos en este recorrido, un poco abigarrado y laberíntico, recuperar escenas, diálogos, personajes que vinculamos -directa o indirectamente- con problemáticas sociales, urbanas, subjetivas, representativas de fenómenos extendidos y vigentes en nuestros espacios de intervención y formación, desde una mirada orientada al análisis crítico de los procesos diferenciales de salud- enfermedad- atención. Desde una tensión entre lógica mercantil - lógica de lo singular consideramos algunos de los interrogantes que vertebraron nuestro pensamiento: ¿cómo es posible resistir a la lógica mercantil imperante? ¿cuál es el sentido de hacerlo en soledad? ¿qué ocurre con la dificultad para construir horizontes colectivos? ¿qué es lo que enfrenta Clara?","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242179,"idioma_id":4,"titulo":"Mechanistic Insight into the Cu-Catalyzed C-S Cross-Coupling of Thioacetate with Aryl Halides. A Joint Experimental-Computational Study","resumen":"The mechanism of the Ullmann-type reaction between potassium thioacetate (KSAc) and iodobenzene (PhI) catalyzed by CuI associated with 1,10-phenanthroline (phen) as a ligand was explored experimentally and computationally. The study on C-S bond formation was investigated by UV-visible spectrophotometry, cyclic voltammetry, mass spectrometry, and products assessment from radical probes. The results indicate that under experimental conditions the catalytically active species is [Cu(phen)(SAc)] regardless of the copper source. An examination of the aryl halide activation mechanism using radical probes was undertaken. No evidence of the presence of radical species was found during the reaction process, which is consistent with an oxidative addition cross-coupling pathway. The different reaction pathways leading to the experimentally observed reaction products were studied by DFT calculation. The oxidative addition-reductive elimination mechanism via an unstable CuIII intermediate is energetically more feasible than other possible mechanisms such as single electron transfer, halogen atom transfer, and &#963;-bond methatesis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242180,"idioma_id":4,"titulo":"Total Oxidation of Naphthalene with Zirconia- Supported Cobalt, Copper and Nickel Catalysts","resumen":"Abstract: ZrO2 nH2O (hydrogel) impregnated with transition metals (Cu, Co, and Ni) was studied in this work as a precursor for the synthesis of CuO\/ZrO2 (CuZ), CoOx\/ZrO2 (CoZ), and NiO\/ZrO2 (NiZ) catalysts, employed in the naphthalene oxidation reaction. Fresh and catalytically used materials were characterized by different physicochemical techniques, to compare the bulk and surface behavior, with particular attention to the effect of the supported metal species? properties on the catalytic activity. Techniques such as X-ray diffraction (XRD), temperature programmed reduction (TPR), differential scanning calorimetry (DSC), Brunauer?Emmett?Teller (BET) surface area analyzer, diffuse reflectance spectroscopy (DRS UV?vis), and Raman spectroscopy, allow for establishing structural and textural aspects of the support, as well as the surface coordination and the accessibility of supported species. Results were in agreement with the CuZ > CoZ > NiZ sequence for the activity in naphthalene oxidation reaction. Electronic properties, ionic sizes, oxide phase deposition on the support surface, reducibility, metal?support interaction, and local site symmetry of metals seem to be decisive factors for the catalytic interaction with the gaseous phase.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242181,"idioma_id":4,"titulo":"Predicting the Bioconcentration Factor Through a Conformation- Independent QSPR Study","resumen":"The ANTARES dataset is a large collection of known and verified experimental bioconcentrationfactor data, involving 851 highly heterogeneous compounds from which 159 of them arepesticides. In this Special Issue devoted to 'Computational Toxicology and Fate of Pesticides?,we predict the Bioconcentration Factor of the ANTARES dataset by means of a conformationindependentQSPR approach. A large number of 27,017 molecular descriptors are explored, withthe main intention of capturing the most relevant structural characteristics affecting the studiedproperty. The structural descriptors are derived with different freewares, such as PaDEL, EpiSuite, CORAL, Mold2, RECON and QuBiLs-MAS, and so it is interesting to find out the way thatthe different descriptor softwares complement each other in order to improve the statistical qualityof the established QSPR. The best multivariable linear regression models are found with theReplacement Method variable subset selection technique. The proposed QSPR model improvesprevious reported models of the bioconcentration factor in the present dataset.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242182,"idioma_id":5,"titulo":"Determinación de anticuerpos \tcontra patógenos virales y bacterianos seleccionados en la población de cerdos silvestres (Sus scrofa) de la Reserva Natural Bahía Samborombón, Argentina","resumen":"Los cerdos silvestres (Sus scrofa) descienden de cruzamientos entre cerdos domésticos libe¬rados durante la colonización con jabalíes salvajes euroasiáticos, liberados con propósitos cinegéticos. Son invasivos y su coexistencia con especies domésticas implica riesgos sanitarios. Argentina es consi¬derada libre de fiebre aftosa (FA), peste porcina clásica (PPC) y africana (PPA) y síndrome reproductivo y respiratorio porcino (PRRS). La enfermedad de Aujeszky (EA) y la leptospirosis son endémicas en ciertas áreas del país. El objetivo fue evaluar la presencia de ciertas enfermedades zoonóticas y\/o de importan¬cia para la producción animal y la conservación de la biodiversidad en cerdos silvestres de la Bahía de Samborombón. Se capturaron 118 animales. Se tomaron muestras de suero, tonsilas, músculo, intestino delgado, linfonódulos, entre otras. Se estudió la presencia de anticuerpos contra Brucella spp., coronavirus respiratorio porcino, virus de la estomatitis vesicular, de la FA, de la gastroenteritis transmisible porcina (TGEV), de la PPC, PPA, EA, PRRS y Leptospira spp. Se realizaron análisis bacteriológicos para Myco¬bacterium spp. Los resultados ratificaron la ausencia de las enfermedades exóticas e indicaron que 36 % de los animales presentó anticuerpos contra Leptospira interrogans serovar pomona y 62,5 % contra el virus de la EA. Estos resultados remarcan la importancia del monitoreo de la interfase productiva\/silvestre en función de la salud pública, producción animal y conservación de la biodiversidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242183,"idioma_id":4,"titulo":"Feature selection for KNN classifier to improve accurate detection of subthalamic nucleus during deep brain stimulation surgery in Parkinson?s patients","resumen":"The tremor and dystonia associated withParkinson?s disease can be treated with deep brain stimulation (DBS) implantedinto the subthalamic nucleus (STN). The accurate STN detection is a complexneurosurgeon task during a DBS surgery since a proper fixing of stimulatingelectrodes will impact on the patient?s future life. The brain electrical signalsobtained with Micro Electrodes Register (MER) are acquired at different depthsof the brain during DBS surgery to detect STN. In our previous work, we foundgood accuracy performance to improve the localization of STN using K-NearestNeighbours (KNN) supervised learning algorithm. However, for real-timeclassification, it is essential to reduce the feature dimension without loss ofclassification accuracy so as to reduce computation time. In this study, wecompared the KNN classification trained with 16 features with other KNN with areduced number of features resulting from applying four feature selectiontechniques. We obtained similar classification results compared to theclassifier using all features, with 6 feature resulting from Branch &amp; Bound(KNN+B) algorithm, &nbsp;giving the bestperformancewith 86.13% accuracy and 92.72% AUC. From the study, we infer thatthe KNN+B classifier has the potential to be used in detecting the STN in realtime","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242186,"idioma_id":5,"titulo":"Comparación de métodos de estimación espectral para señales neurales de microelectrodos obtenidas de pacientes con Parkinson","resumen":"En este trabajo se analizaron diferentes métodosde estimación del espectro de potencia de señales MER de pacientes con Enfermedadde Parkinson, a fines de escoger de manera justificada el método más eficazpara la detección, en tiempo real, de la potencia elevada en la banda &#946; de frecuencias.Particularmente, se compararon losresultados de tres métodos no parámetricos (periodograma, método de Welch ymultitaper) y un método parámetrico (modelo autorregresivo), cada uno de elloscon distintos conjuntos de parámetros, dando un total de ocho estimacionesespectrales. Se concluyó que el método óptimo, entre los analizados, pararealizar la estimación espectral en tiempo real de registros MER de pacientescon Enfermedad de Parkinson es el de Welch con ventanas Hamming de 1.5 segundosy solapamiento del 50%.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242189,"idioma_id":5,"titulo":"Revisi&oacute;n del perezoso terrestre Nothropus (Mammalia, Xenarthra, Tardigrada) del Pleistoceno de Argentina y Bolivia","resumen":"REVIEW OF THE GROUND SLOTH NOTHROPUS (MAMMALIA, XENARTHRA, TARDIGRADA)FROM THE PLEISTOCENE OF ARGENTINA AND BOLIVIA. The Nothrotheriinae Ameghino (Xenarthra, Pilosa) arerecorded in Argentina from the middle Miocene to the late Pleistocene. In the Quaternary of the current territories of Argentinaand Bolivia it is possible to recognize the existence of the genus Nothropus Burmeister, which includes three Pleistocene species,all of them known only by their type materials: (i) Nothropus priscus Burmeister (Santa Fe Province, Argentina); (ii) Nothropuscarcaranensis Bordas (Santa Fe Province, Argentina); (iii) Nothropus tarijensis (Burmeister) (Tarija Valley, Bolivia). This studyshows that N. priscus is a juvenile specimen and must be considered as a species inquirenda. In turn, the mandible morphologyof N. tarijensis is very different compared to that of N. priscus and N. carcaranesis. N. tarijensis shows a very robust dentary anda greater angle between the occlusal plane and the anterior margin of the ascending ramus, suggesting that this is a valid species.In summary, the evidence suggests that the diversity of Nothropus is limited to two species: N. carcaranensis in Argentina and N.tarijensis in Bolivia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242190,"idioma_id":4,"titulo":"The Environmental Acinetobacter baumannii Isolate DSM30011 Reveals Clues into the Preantibiotic Era Genome Diversity, Virulence Potential, and Niche Range of a Predominant Nosocomial Pathogen","resumen":"Acinetobacter baumannii represents nowadays an important nosocomial opportunistic pathogen whose reservoirs outside theclinical setting are obscure. Here, we traced the origins of the collection strain A. baumannii DSM30011 to an isolate firstreported in 1944, obtained from the enriched microbiota responsible of the aerobic decomposition of the resinous desert shrubguayule. Whole-genome sequencing and phylogenetic analysis based on core genes confirmed DSM30011 affiliation toA. baumannii. Comparative studies with 32 complete A. baumannii genomes revealed the presence of 12 unique accessorychromosomal regions in DSM30011 including five encompassing phage-related genes, five containing toxin genes of the type-6secretion system, and one with an atypical CRISPRs\/cas cluster. No antimicrobial resistance islands were identified in DSM30011agreeingwithageneralantimicrobialsusceptibilityphenotypeincludingfolatesynthesisinhibitors.Themarginalampicillinresistanceof DSM30011 most likely derived from chromosomal ADC-type ampC and blaOXA-51-type genes. Searching for catabolicpathways genes revealed several clusters involved in the degradation of plant defenses including woody tissues and a previouslyunreported atu locus responsible of aliphatic terpenes degradation, thus suggesting that resinous plants may provide an effectiveniche for this organism. DSM30011 also harbored most genes and regulatory mechanisms linked to persistence and virulence inpathogenicAcinetobacterspecies. This strain thus revealed important clues into the genomic diversity, virulence potential, and nicheranges of the preantibiotic era A. baumannii population, and may provide an useful tool for our understanding of the processesthat led to the recent evolution of this species toward an opportunistic pathogen of humans","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242191,"idioma_id":4,"titulo":"Contrasting structural patterns of the mesozooplankton community result from the development of a frontal system in San Jos&eacute; Gulf, Patagonia","resumen":"The structural patterns of the mesozooplankton community of San José Gulf (SJG), a one of a kind semi-enclosed basin located in the northern margin of the Valdés Peninsula (Argentine Patagonia), were studied by means of semiautomatic image analysis. Samples were obtained bimonthly during the warm season (October 2012-April 2013) at stations distributed on a regular grid. Cluster analyses outlined two spatially consistent groups of stations showing similar patterns when based on physical (SST, Chl-a, and bottom depth) and community structure (abundance, biomass, and slope of the size spectra) descriptors, each broadly distributed on one of two previously described hydrographic domains formed by the interaction of tidal circulation, coastal morphology, bottom topography, and seasonal vertical stratification. Examination of the slope of the mesozooplankton size spectra revealed that the stratified waters of the East Domain sustain higher proportions of small organisms and higher biomass, suggesting potentially low trophic transfer efficiency compared to its vertically-mixed West counterpart. Three-clustering analyses resulted in still spatially consistent groups of stations when based on the community descriptors, revealing the existence of a transition zone, presumably resulting from intermediate hydrodynamic conditions. Principal component analysis revealed that biomass of cladocerans modulates the size spectra and is related with distances from sampling stations to SJG´s mouth. Overall, a consistent spatial correlate was found between physical conditions of water masses and the structure of the mesozooplancton community contained within.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242193,"idioma_id":4,"titulo":"Spatial and temporal characterization of progressive deformation during orogenic growth: example from the Fuegian Andes, southern Argentina","resumen":"Superposed structural fabrics in the easternmost Fuegian Andesreveal two distinct, non-coaxial deformation phases across the transitionfrom the orogenic core to the thrust-fold belt. Each phase ischaracterized by different metamorphic conditions and consistentlydifferent orientations, which allow the structural correlation betweenthe orogenic core and the internal thrust-fold belt. The firstdeformation phase was coeval with regional metamorphism reaching uppergreenschist facies, and featured simple shear deformation of the basement(Paleozoic and Jurassic) and cover (Cretaceous) in the top of theunderthrusting South American plate. The second phase developed duringcollision of the orogenic wedge with the Río Chico Arch, a promontory inthe underthrusting plate; this phase was characterized by thrust sheetemplacement and formation of a crustal duplex, with rock uplift andconsequent low to very-low grade metamorphism. Buttressing against theRío Chico Arch is responsible for the change in shortening orientationthat distinguishes both phases.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242194,"idioma_id":4,"titulo":"New species, new taxon report and biogeography of the diatom genus Gomphoneis Cleve (Bacillariophyceae) in Patagonia, Chubut Province, Argentina","resumen":"The presence of three Gomphoneis species from Chubut Province in Argentina is documented with light and scanning electronmicroscopy. Two of the taxa, G. patagoniana and G. eriense var. variabilis, are part of the Herculeana subgroup of Gomphoneis. Gomphoneispatagoniana is a newly discovered species and G. eriense var. variabilis is reported from Argentina for the first time. These twospecies have evident axial plates, differentiated apical pore fields (APFs), a stigmal opening that is round externally and slit-like internally,&nbsp; and areolae that are mostly tri-radiate in shape. The third species, G. frenguellii, is also newly discovered and described. Presence of four isolated stigmoids, undifferentiated APFs and lack of an axial plate indicates G. frenguellii is a member of the Elegans subgroup of the genus. Presence of these newly described species, and the previously unreported taxon, may also be associated with the invasive species Didymosphenia geminata. Given there is no long history of reports of Gomphoneis in the country and, in the case of G. eriense var. variabilis, its previously known distribution, it is possible that the origin of this Gomphoneis taxon is from western North America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242195,"idioma_id":5,"titulo":"Carcinoma espinocelular cutáneo invasivo de alto riesgo: uso de clasificaciones actuales","resumen":"Introducción: el carcinoma espinocelular cutáneo de alto riesgo, se define como aquel que tiene un riesgo de recidiva y metástasis ganglionares y\/o a distancia mayor del 5%, debido a ello, es preponderante el conocimiento de los factores que lo convierten en un tumor de alto riesgo, para lograr su identificación y de este modo, realizar el tratamiento y seguimiento adecuados. Objetivos: estimar la prevalencia del carcinoma espinocelular cutáneo de pacientes, que acuden a la consulta externa del Hospital Privado Universitario de Córdoba y del Hospital Raúl Ferreyra, en el período de Julio 2014 a Diciembre de 2015. Calcular la prevalencia del carcinoma espinocelular invasivo, además de describir las características epidemiológicas, clínicas e histopatológicas de alto riesgo de los CEC invasivos. Determinar el porcentaje de pacientes con CEC de alto riesgo, según la clasificación de la American Joint Committee on Cancer (AJCC). Determinar el porcentaje de CEC de alto riesgo, según la clasificación  propuesta por la National Comprenhensive Cancer Network  (NCCN). Comparar los porcentajes de pacientes con CEC invasivo de alto riesgo, que se obtuvieron mediante la aplicación  de los sistemas de evaluación actuales AJCC y NCCN. Materiales y Métodos: se realizó un estudio retrospectivo descriptivo, con  recolección directa de información del reporte de histopatología,  incluido en la base de datos del archivo de Patología del  Hospital Privado Universitario de Córdoba, con posterior revisión de  las historias clínicas de cada uno de los pacientes incluidos y se completó una ficha diseñada a tal efecto. Con los datos obtenidos se completaron planillas de excel; los factores clínicos tomados en cuenta incluyeron: sexo, edad al momento del diagnóstico, historia de  inmunosupresión, sitios de inflamación crónica, localización, tamaño del tumor  y dentro de las características histopatológicas, se incluyeron: variantes histológicas, diferenciación,  Breslow, Clark e invasión perineural. Los datos obtenidos se sometieron a cada una de las clasificaciones: AJCC 2010 y de la NCCN 2013. Resultados: la prevalencia del carcinoma espinocelular en nuestra población fue de 0,24% y la del CEC invasivo respecto del CEC cutáneo, del 59%. En nuestra población de 78 pacientes el 100% eran argentinos de raza caucásica, encontramos que la  mediana de edad fue de 75,5 años; el rango de pacientes entre 61 y 90 años fueron los más afectados incluyendo el 80,7% de los mismos. Respecto del sexo la mayoría de los pacientes fueron hombres 49 (63%) y las localizaciones más afectadas fueron: cabeza y cuello con 57(68%). En nuestra  cohorte, se obtuvieron 34(40%) de tumores, que según los criterios de clasificación AJCC se denominarían como: T2 (de alto riesgo)  mientras que la mayoría 74 (88%) son de 'alto riesgo' de acuerdo con las guías de la NCCN. Conclusiones: en resultados respondimos a los objetivos propuestos, sobre prevalencia  del carcinoma espinocelular y carcinoma espinocelular de alto riesgo (CEAR) en nuestra población y las características epidemiológicas de nuestra serie. Al comparar los sistemas de clasificación de la AJCC y la NCCN y someter nuestra serie a éstos, según la AJCC: 34 pacientes (40%) corresponden a CECAR en tanto que por la NCCN a 74 pacientes (88%). Se realizó el cálculo del índice kappa 0,47, con un grado de acuerdo entre ambas clasificaciones del 73% (moderado). Podemos al analizar la tabla  inferir que todos los tumores que fueron de bajo riesgo para NCCN, lo fueron también para AJCC y todos los tumores que fueron de alto riesgo para AJCC también para NCCN. El propósito del sistema de estadificación AJCC es distinto a las guías de tratamiento de la NCCN. El objetivo del sistema de estadificación del AJCC es estratificar a los pacientes con similares resultados en grupos, para ofrecer estimaciones precisas de pronóstico, mientras que las guías de la NCCN se destinan a dirigir el manejo, tratamiento y seguimiento del CEC. Por lo tanto, cada una tiene sus objetivos definidos y debe ser empleada de acuerdo con el uso que pretendamos darle.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242196,"idioma_id":5,"titulo":"Manejo nutricional de la Diabetes tipo II en el adulto. Índice glicémico de los alimentos","resumen":"Numerosos estudios han demostrado la efectividad de la terapia nutricional en el control de la glucemia y su influencia en la normalización de la presión arterial y el perfil lipídico. El objetivo es entregar a los profesionales que atienden a personas con diabetes un documento con recomendaciones nutricionales estandarizadas  y basadas en evidencias científicas. Se entregan recomendaciones de energía y macronutrientes para el diabético tipo II adulto, su distribución y fraccionamiento. Las recomendaciones de edulcorantes están estandarizadas, al igual que el consumo de sodio, vitaminas y minerales. Se consideran otros tipos de dietas que han sido recomendadas y han tenido efectos beneficiosos en el control metabólico, como la dieta mediterránea y la dieta Dietary Approaches to stop hypertension (DASH). El índice glicémico (IG) es una herramienta útil al planificar la alimentación del diabético. Una dieta de bajo IG permite relentizar la elevación de la glucemia despúes de la ingesta de alimentos. La evidencia revisada permite concluir que las personas con diabetes mellitus tipo II que son capaces de disminuir su peso entre un 5 a 10%, y tienen un plan de alimentación saludable con porciones adecuadas de alimento y un programa de ejercicios pueden lograr un buen control metabólico y mejorar su presión arterial y perfil lipídico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242197,"idioma_id":5,"titulo":"Vasculopatía livedoide: a propósito de un caso","resumen":"La vasculopatía livedoide es una enfermedad trombo-oclusiva no inflamatoria, rara, crónica y recurrente. Presenta características clínicas e histológicas distintivas, que la diferencian de las verdaderas vasculitis inflamatorias. Algunos casos se asocian con anormalidades en la coagulación o a otras enfermedades, principalmente autoinmunes. Presentamos el caso de una paciente, en la cual no se encontraron alteraciones asociadas y realizamos una breve revisión de la literatura.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242198,"idioma_id":4,"titulo":"Accumulation of current-use pesticides, cholinesterase inhibition and reduced body condition in juvenile one-sided livebearer fish (Jenynsia multidentata) from the agricultural Pampa region of Argentina","resumen":"The aim of this study was to characterize the level and nature of the pesticide contamination received by one-sided livebearer fish (Jenynsia multidentata) from a watercourse situated within the main agricultural region of Argentina, and to assess the effects of this contamination on fish health. Juvenile one-sided livebearer fish (Jenynsia multidentata) were collected in December 2011 and March 2012 from three sites along the Pergamino River. Pesticide contamination was characterized by extracting whole fish and analytically determining thirty different pesticide molecules. The biomarkers catalase, glutathion-S-transferase, and cholinesterases were assessed. Body condition was calculated as an estimate of the amount of energy reserves possessed by the fish. Seventeen different pesticides were detected in fish tissues with 81% of captured animals containing at least one pesticide molecule. The pyrethroid insecticides fenvalerate and bifenthrin were most frequently detected, being respectively found in 41.8 and 36.4% of samples tested. Highly toxic dichlorvos and pirimiphos-methyl were detected. Differential levels of contamination could not be established amongst sites but were observed within sites amongst the two sampling dates. The months when pesticide residues were most abundant from Site A and B corresponded to the months when body condition was at its lowest in the two sites. The inibition of Che activity in March when body condition was reduced also points to a role of insecticide contamination in the reduction of body condition. These findings provide strong new evidence that current-used agricultural pesticides can accumulate in wild fish and impact their health and energetics.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242200,"idioma_id":5,"titulo":"Invocaciones. Apuntes sobre curaduría teatral","resumen":"Desde 2014 se presenta en el Centro Cultural General San Martín Invocaciones, con curaduría de Mercedes Halfon. La propuesta es convocar a diferentes directores argentinos para leer y poner en escena el legado teatral del siglo XX. A primera vista la curaduría teatral aparece como una actividad incipiente, aunque se pueden rastrear otros proyectos que, desde mediados de los años 90, marcan un estilo curatorial para el teatro local. Un recorrido por el ciclo Invocaciones y una perspectiva más general de algunos de sus antecedentes nos permitirá trazar un mapa de la práctica en este campo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242201,"idioma_id":4,"titulo":"A Web-Based Approach for Analyzing Microorganism Sequences","resumen":"In biology, a mutation is a change in the nucleotide sequence of the genome of a microorganisms (e.g., virus, bacteria). Mutations play an important role in biological processes of microorganisms such as drug resistance. Analyzing these mutations becomes a challenge because microorganisms are described by a big amount of data that must be processed based on reference microorganisms data. Nowadays, scientists in health areas make these analyses manually or using standalone software that provide results in plain text formats, which limit their interpretations. In this paper, we present an approach for analyzing microorganism pathogens. The analysis is performed using the information contained in the nucleotide sequence and comparing it to reference sequences. This approach allows users to calculate changes of nucleotide and amino acid from selected sequences obtained using conventional Sanger and cloning sequencing techniques. The results of our approach are deployed using different visualization techniques that facilitate results interpretation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242202,"idioma_id":4,"titulo":"Pathogen Sequence Signature Analysis (PSSA): A software tool for analyzing sequences to identify microorganism genotypes.","resumen":"IntroductionThe chikungunya virus (CHIKV) is an arbovirus vectored by Aedes mosquitoes that infects humans in tropical and sub-tropical areas of Asia and Africa. Recently, outbreaks have been reported in tropical and sub-tropical areas of countries that were previously unaffected (e.g., Brazil, Colombia). Currently, the following geographical genotypes have been identified through phylogenetic analysis of CHIKV E1 gene sequences: the West African (WAf), East\/Central\/South African (ECSA), and Asian genotypes. Outbreaks in a geographical area can happen with the same or different genotypes. Determining which genotypes are circulating in an outbreak is important for public health management.ObjectivesTo create a computer-based system available online that is suitable for detecting changes in CHIKV nucleotide and amino acid sequences and identifying their corresponding geographical genotype.MethodsWe used several computer frameworks, tools, programming languages, algorithms, and infrastructure systems to build a software tool that analyzes changes in nucleotide and amino acid sequences and identifies different geographical genotypes through phylogenetic analysis.ResultsWe have built an online software tool called Pathogen Sequence Signature Analysis (PSSA) that allows researchers to analyze nucleotide and amino acid sequence variations between sample CHIKV sequences taken from infected patients and obtained through conventional Sanger sequencing, to identify their corresponding geographical genotype.ConclusionPSSA is able to analyze sequences in a simple and effective manner, and includes proper documentation (i.e., UML diagrams) and also basic examples that serve to test the algorithm. Furthermore, PSSA provides various ways to visualize the data in order to aid understanding and interpretation of results.Results provided by PSSA will be useful for the identification of circulating CHIKV genotypes and public health surveillance. PSSA is available at: http:\/\/pssa.itiud.org.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242204,"idioma_id":5,"titulo":"El pensamiento crítico a través de las experiencias estéticas","resumen":"El presente artículo intenta abrir el debate en relación a las experienciasestéticas -principalmente las producciones audiovisuales- como recurso didáctico y deapoyo metodológico para la motivación del pensamiento crítico y la formulación de losproyectos de investigación de los estudiantes que transitan el Seminario de Integración.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242206,"idioma_id":4,"titulo":"Nutraceutical emulsion containing valproic  acid (NE-VPA): a drug delivery system for  reversion of seizures in zebrafish larvae  epilepsy model","resumen":"Valproic acid (VPA) is an antiepileptic drug, which is currently used in neurodegenerative diseases. However, a high dose is required to obtain a therapeutic effect. Long-chain polyunsaturated fatty acids (PUFAs), such as omega 3 and omega 6, are efficient complements in treatments for neurological diseases. Previous studies have reported that a dietary supplement containing PUFAs together with the administration of antiepileptic drugs significantly reduces the frequency of seizures. Based on this, the main goal of this work was to obtain a complex based on VPA encapsulation in an oil\/water (o\/w) nutraceutical emulsion (NE) enriched with PUFAs for oral administration. Besides, encapsulation of VPA might reduce its dose and increase its therapeutic effect. In order to study its effect, we used a zebrafish larvae model of induced epileptiform behavior with the proconvulsant drug pentylenetetrazol (PTZ). Results have shown that when 100 &#956;M VPA and fatty acids were combined in the NE (NE-VPA), the epileptiform behavior of PTZ-treated zebrafish larvae decreased significantly. Additionally, morphological changes, hepatotoxicity, lethality and heart rate were studied. Despite the fact that a high dose of VPA exerted a cardiotoxic effect, this was no longer detected after addition of this drug in the NE. This treatment exerted a significant antiepileptic effect and did not result in highly toxic or lethal effects. In order to develop an improved pharmaceutical treatment, and considering that all the components used are FDA approved for consumption, the NE-VPA selected might be easily incorporated into clinical trials.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242207,"idioma_id":4,"titulo":"Relation between biophysical properties of nanostructures and their toxicity on zebrafish","resumen":"In recent years, the use of commercial nanoparticles in different industry and health fields has increased exponentially. However, the uncontrolled application of nanoparticles might present a potential risk to the environment and health. Toxicity of these nanoparticles is usually evaluated by a fast screening assay in zebrafish (Danio rerio). The use of this vertebrate animal model has grown due to its small size, great adaptability, high fertilization rate and fast external development of transparent embryos. In this review, we describe the toxicity of different micro- and nanoparticles (carbon nanotubes, dendrimers, emulsions, liposomes, metal nanoparticles, and solid lipid nanoparticles) associated to their biophysical properties using this model. The main biophysical properties studied are size, charge and surface potential due to their impact on the environment and health effects. The review also discusses the correlation of the effects of the different nanoparticles on zebrafish. Special focus is made on morphological abnormalities, altered development and abnormal behavior. The last part of the review debates changes that should be made in future directions in order to improve the use of the zebrafish model to assess nanotoxicity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242208,"idioma_id":4,"titulo":"Skin penetration and UV-damage prevention by nanoberries","resumen":"Background: Ethanolic extract from blueberry (Vaccinium myrtillus) is rich in anthocyanins and thus exhibits antioxidant activity. On the other hand, ultradeformable liposomes are capable of penetrating to the impermeable barrier of skin. Nanoberries are ultradeformable liposomes carrying blueberry extract. Objectives: In this study, their capacity to penetrate the stratum corneum and photodamage prevention were tested, with the aim of developing a topical formulation for skin protection from environmental damage. Methods: Nanoberries were prepared by lipid film resuspension with ethanolic extract from blueberry, followed by sonication and incorporation to a gel. Size, zeta potential, deformability, rheology and viscoelasticity were determined. Toxicity was assessed in vivo in zebrafish model, while in vitro cytotoxicity assay was performed on HaCaT and HEK-293T cell lines. Skin penetration was evaluated with the Saarbrücken Penetration Model followed by tape stripping, cryosection or optical sectioning. UV-damage and photoprotection were determined by ad-hoc methods with UVA, UVB and UVC radiation on HaCaT cells. Wound assay was performed on HaCaT cells. Results: Nanoberries of about 100 nm, with differential elastic properties, did penetrate the stratum corneum, with low toxicity. When HaCaT cells were exposed to UV radiation in presence of nanoberries, their viability was mantained. Conclusions: Nanoberries could be effective to protect the skin from sun photodamage","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242209,"idioma_id":4,"titulo":"Nanotoxicological and teratogenic effects: A linkage between dendrimer surface charge and zebrafish developmental stages","resumen":"This article reports novel results about nanotoxicological and teratogenic effects of the PAMAM dendrimers DG4 and DG4.5 in zebrafish (Danio rerio). Zebrafish embryos and larvae were used as a rapid, high-throughput, cost-effective whole-animal model. The objective was to provide a more comprehensive and predictive developmental toxicity screening of DG4 and DG4.5 and test the influence of their surface charge. Nanotoxicological and teratogenic effects were assessed at developmental, morphological, cardiac, neurological and hepatic level. The effect of surface charge was determined in both larvae and embryos. DG4 with positive surface charge was more toxic than DG4.5 with negative surface charge. DG4 and DG4.5 induced teratogenic effects in larvae, whereas DG4 also induced lethal effects in both zebrafish embryos and larvae. However, larvae were less sensitive than embryos to the lethal effects of DG4. The platform of assays proposed and data obtained may contribute to the characterization of hazards and differential effects of these nanoparticles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242211,"idioma_id":10,"titulo":"'Regresión. Las nuevas políticas para medios comunitarios en Argentina'","resumen":"Nuestra hipótesis es la siguiente. Históricamente, las políticas públicas de comunicación ayudaron a construir una posición de desventaja en términos de sostenibilidad económica de los medios comunitarios, populares y alternativos de Argentina, con respecto a los medios de propiedad privada con fines de lucro y a los estatales. Después de una breve etapa entre 2009 y 2015 en la que las políticas dirigidas al sector no lucrativo se orientaron -con sus demoras y problemas- a su legalización y fomento, las políticas del gobierno actual, aunque no modificaron el marco legal, restauran las persecuciones a las radios en situación de ilegalidad forzosa.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242213,"idioma_id":4,"titulo":"Abscopal effect of boron neutron capture therapy (BNCT): proof of principle in an experimental model of colon cancer","resumen":"The aim of the present study was to evaluate, for the first time, the abscopal effect of boron neutron capture therapy (BNCT). Twenty-six BDIX rats were inoculated subcutaneously with 1 × 106 DHD\/K12\/TRb syngeneic colon cancer cells in the right hind flank. Three weeks post-inoculation, the right leg of 12 rats bearing the tumor nodule was treated with BPA-BNCT (BPA-Boronophenylalanine) at the RA-3 nuclear reactor located in Buenos Aires, Argentina, at an absorbed dose of 7.5 Gy to skin as the dose-limiting tissue. The remaining group of 14 tumor-bearing rats were left untreated and used as control. Two weeks post-BNCT, 1 × 106 DHD\/K12\/TRb cells were injected subcutaneously in the contralateral left hind flank of each of the 26 BDIX rats. Tumor volume in both legs was measured weekly for 7 weeks to determine response to BNCT in the right leg and to assess a potential influence of BNCT in the right leg on tumor development in the left leg. Within the BNCT group, a statistically significant reduction was observed in contralateral left tumor volume in animals whose right leg tumor responded to BNCT (post-treatment\/pre-treatment tumor volume <1) versus animals who failed to respond (post\/pre &#8805;1), i.e., 13 ± 15 vs 271 ± 128 mm3. In addition, a statistically significant reduction in contralateral left leg tumor volume was observed in BNCT-responsive animals (post\/pre <1) vs untreated animals, i.e., 13 ± 15 vs 254 ± 251 mm3. The present study performed in a simple animal model provides proof of principle that the positive response of a tumor to BNCT is capable of inducing an abscopal effect.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242214,"idioma_id":4,"titulo":"Photon iso-effective dose for cancer treatment with mixed field radiation based on dose-response assessment from human and an animal model: Clinical application to boron neutron capture therapy for head and neck cancer","resumen":"Boron neutron capture therapy (BNCT) is a treatment modality that combines different radiation qualities. Since the severity of biological damage following irradiation depends on the radiation type, a quantity different from absorbed dose is required to explain the effects observed in the clinical BNCT in terms of outcome compared with conventional photon radiation therapy. A new approach for calculating photon iso-effective doses in BNCT was introduced previously. The present work extends this model to include information from dose-response assessments in animal models and humans. Parameters of the model were determined for tumour and precancerous tissue using dose-response curves obtained from BNCT and photon studies performed in the hamster cheek pouch in vivo models of oral cancer and\/or pre-cancer, and from head and neck cancer radiotherapy data with photons. To this end, suitable expressions of the dose-limiting Normal Tissue Complication and Tumour Control Probabilities for the reference radiation and for the mixed field BNCT radiation were developed. Pearson´s correlation coefficients and p-values showed that TCP and NTCP models agreed with experimental data (with r > 0.87 and p-values >0.57). The photon iso-effective dose model was applied retrospectively to evaluate the dosimetry in tumours and mucosa for head and neck cancer patients treated with BNCT in Finland. Photon iso-effective doses in tumour were lower than those obtained with the standard RBE-weighted model (between 10% to 45%). The results also suggested that the probabilities of tumour control derived from photon iso-effective doses are more adequate to explain the clinical responses than those obtained with the RBE-weighted values. The dosimetry in the mucosa revealed that the photon iso-effective doses were about 30% to 50% higher than the corresponding RBE-weighted values. While the RBE-weighted doses are unable to predict mucosa toxicity, predictions based on the proposed model are compatible with the observed clinical outcome. The extension of the photon iso-effective dose model has allowed, for the first time, the determination of the photon iso-effective dose for unacceptable complications in the dose-limiting normal tissue. Finally, the formalism developed in this work to compute photon-equivalent doses can be applied to other therapies that combine mixed radiation fields, such as hadron therapy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242215,"idioma_id":5,"titulo":"Prólogo y compiladora del volumen 'Arqueología y Etnohistoria'","resumen":"Compiladora del Volumen Arqueología y Etnohistoria","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242216,"idioma_id":5,"titulo":"Trabajo Doméstico y Buen Vivir. Un desafío para las narrativas publicitarias","resumen":"Las nociones de estereotipo, el sexismo y la violencia simbólica no son solamente categorizaciones habituales en trabajos de análisis de avisos y campañas, sino que, gracias al esfuerzo militante de muchas organizaciones e iniciativas pedagógicas, han comenzado a formar parte de la doxa mediática y del lenguaje cotidiano. En este trabajo se pretende dar cuenta de las observaciones realizadas durante los casi diez años de existencia del Observatorio Publicitario sobre Sexismo de la Licenciatura en Publicidad de la Universidad Abierta Interamericana, describiendo constantes y transformaciones observadas y atendiendo en particular al modo en que ha sido representado el trabajo doméstico y las reflexiones que estas representaciones generan.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242217,"idioma_id":5,"titulo":"FEMINISMOS Y CIENCIAS SOCIALES. PROPUESTAS PEDAGÓGICAS Y APORTES CRÍTICOS PARA REVISAR PROGRAMAS DE FORMACIÓN EN EL GRADO","resumen":"En este trabajopresentamos los avances producidos en el marco del proyecto de investigación Feminismo y Ciencias Sociales: procedencias,inserciones y carencias en el diseño curricular, que tiene el propósito de problematizarlos enfoques teórico-epistemológicos predominantesen las propuestas académicasde formación en ciencias sociales. Como parte de las tareas de investigación propusimosrevisar los programas de asignaturas correspondientes a las licenciaturas enCiencia Política, Comunicación Social, Relaciones Internacionales y TrabajoSocial que se imparten en la Facultad de Ciencia Política y RelacionesInternacionales (RR. II.) de la Universidad Nacional de Rosario (UNR). Esta setradujo en una propuesta pedagógica desarrollada junto lxs estudiantes quecursan la unidad electiva Introducción ala Perspectiva de Género en la misma Facultad. Aquí reflexionamos sobre losresultados de este ejercicio investigativo revisando las categorías hegemónicasqueestán presentes en los programas elaborados para la formación deprofesionales cuyos perfiles se orientan a investigar, planificar, interveniren diversos ámbitos y situaciones sociales, y nos preguntamos por lasausenciasqueimposibilitan reconocer los condicionamientos estructurales de un sistemapatriarcal y heterosexista dónde el género y la sexualidad constituyen, junto conlas posiciones de clase, étnicas-raciales, nacionales y generacionales, marcasque determinan las coordenadas de lxssujetxs (ver nota 2) en las asimétricasrelaciones de poder.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242219,"idioma_id":4,"titulo":"Magnetostratigraphy of the Rabot Formation, Upper Cretaceous, James Ross Basin, Antarctic Peninsula","resumen":"Problems of endemism and diachronous extinctions make global correlation of coeval strata in the mid Campanian-Maastrichtian of the James Ross Basin problematic. To provide a more precise chronological framework, we present two magnetostratigraphies of Campanian strata from the Rabot Formation that crops out at Hamilton Norte (200 m thick) and Redonda Point (340 m thick) in James Ross Island. Sampled sections consist of poorly-consolidated, drab-colored fine sandstones and mudstones. Bulk susceptibility logs of both sections show a similar pattern of relatively low values at the lower and upper levels with significantly higher values at mid-levels that confirms the lithostratigraphic correlation between sections. Rock magnetic studies suggest that this change is not attributable to a ferrimagnetic fraction but to a paramagnetic contribution of presumed detrital origin. Stepwise thermal demagnetization showed dominant unblocking temperatures higher than 400 °C. Progressive hybrid low-temperature cycling, low-field AF and thermal demagnetization in a controlled N2 atmosphere, reveals a two-polarity characteristic component of possible primary origin. Rock magnetic experiments suggest that detrital titano-magnetite is the most likely remanence carrier. Anisotropy of magnetic susceptibility results show sedimentary fabrics, indicating that beds were not significantly buried or compacted. Magnetostratigraphies produced at each locality demonstrate a consistent change from reverse to normal polarity remanence in the middle of the sections. Biostratigraphic constraints identify this reversal as the C33r\/C33n transition, indicating a 79.90 Ma depositional age for this level of the Rabot Formation. The remanence directions yield a mean whose corresponding paleopole is consistent with two recently obtained Upper Cretaceous reference paleopoles for the Antarctic Peninsula. Our data support the lack of tectonic rotation or oroclinal bending of this region since the Late Cretaceous.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242220,"idioma_id":4,"titulo":"Absolute ages of marine sedimentary strata from James Ross Basin","resumen":"A magnetostratigraphic study was carriedout in the SE sector of the James Ross Basin (Antarctica). Themagnetostratigraphy was obtained along five cross-sections, three of themlocated in the SE sector of James Ross Island and two in Snow Hill Island. Theybelong to the upper part of the deep marine sedimentary succession thatconstitute the Marambio Group (Upper Cretaceous). The main chronologicalreference framework is given by ammonite assemblages. Even though the fossilcontent is abundant, endemism and diachronic extinctions are the main problemsin the definition of a precise age framework and global correlations for theUpper Cretaceous units. In this scenario, the magnetostratigraphy provides the requiredchronological resolution for the global correlation problems of James RossBasin, identifying seven geomagnetic polarity reversals and obtaining an absoluteage constraint for the whole succession between 74.309 Ma (Middle Campanian) to71.449 Ma (Early Maastrichtian). ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242224,"idioma_id":4,"titulo":"Magnetic fabrics and microstructures of late to post-tectonic Paleoproterozoic intrusive bodies of the Piedra Alta Terrane, Río de la Plata Craton, Uruguay","resumen":"Nine paleoproterozoic intrusive bodies of the Piedra Alta terrain, in the west of Uruguay, with ages between 2.2 and 2.0Ga were sampled in order to obtain information on kinematics of the intrusives emplacement, degree of deformation and regional stress regime during intrusion from anisotropy studies of magnetic susceptibility (AMS). Petrographic thin sections were studied in order to obtain information about the degree of deformation and its potential influence in the AMS results. Most plutons show K1 subvertical axes and subvertical foliations planes with K3 in subhorizontal position suggesting an extensional N-S regional field controlling the magma ascent. This is consistent with the E-W structural grain of the Piedra Alta terrane, the geographic distribution of the plutons in the metamorphic San José belt.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242225,"idioma_id":4,"titulo":"Absolute Ages of Marine Sedimentary Strata from James Ross Basin","resumen":"A magnetostratigraphic study was carried out in the SE sector of the James Ross Basin (Antarctica). The magnetostratigraphy was obtained along five cross-sections, three of them located in the SE sector of James Ross Island and two in Snow Hill Island. They belong to the upper part of the deep marine sedimentary succession that constitute the Marambio Group (Upper Cretaceous). The main chronological reference framework is given by ammonite assemblages. Even though the fossil content is abundant, endemism and diachronic extinctions are the main problems in the definition of a precise age framework and global correlations for the Upper Cretaceous units. In this scenario, the magnetostratigraphy provides the required chronological resolution for the global correlation problems of James Ross Basin, identifying seven geomagnetic polarity reversals and obtaining an absolute age constraint for the whole succession between 74.309 Ma (Middle Campanian) to 71.449 Ma (Early Maastrichtian)","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242226,"idioma_id":5,"titulo":"Innovadores, adaptaciones creativas y proyectos «nacionales». La circulación de ideas en las ciencias sociales argentinas (1950-1976)","resumen":"Entre las décadas de 1950 y 1970 las ciencias sociales argentinas experimentaron un pluralismo teórico que combinó diversos procesos de espacialización de teorías provenientes de los centros metropolitanos de producción de conocimiento. Esas adaptaciones, más o menos creativas, convivieron con propuestas de formular teorías endógenas guiadas por un compromiso militante y el afán de transformación social. En el marco de su definitiva institucionalización, disciplinas como antropología y sociología tuvieron referentes académicos que, en general desde sus anclajes institucionales, marcaron el pulso de las discusiones teóricas, en muchos casos atravesados por la coyuntura política. Aunque los legados que dejaron esos cientistas sociales para el devenir de cada una de las disciplinas fue dispar, constituyen una marca indeleble de como se practicaban las ciencias sociales en la Argentina y de los conflictos que dominaron el campo de las ciencias sociales durante tres décadas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242228,"idioma_id":5,"titulo":"Estudio bibliométrico de la producción científica Argentina en cáncer a través de las bases de datos Medline y Lilacs","resumen":"Este artículo analiza el perfil de la producción científica argentina en el campo del cáncer entre 2001 y 2010. Una investigación bibliométrica se realizó a través de las bases de datos Medline y Lilacs.En Medline, se registraron 1132 documentos. El núcleo de Bradford estuvo conformado por 37 revistas con 379 publicaciones. El Instituto de Oncología Ángel H. Roffo (UBA) fue la institución más productiva (71 documentos). En Lilacs, se registraron 824 documentos. El núcleo de Bradford estuvo conformado por cinco revistas con 291 publicaciones. El Hospital Italiano (CABA) fue la institución más productiva (86 documentos).La investigación en cáncer en Argentina se está incrementando, existe una fuerte producción en las Universidades Nacionales (Medline), Hospitales nacionales y provinciales (Lilacs), con importante participación en investigaciones observacionales descriptivas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242230,"idioma_id":5,"titulo":"Perfiles de actividad eléctrica cortical Beta 3 en tareas de cálculos matemáticos sencillos e imaginación de objetos. Un estudio descriptivo","resumen":"En el presente estudio se muestran los patrones grupales de activación cortical registrados por un electroencefalógrafo digital, de 21 canales, durante la resolución de cálculos matemáticos y la evocación imaginaria de objetos en sujetos jóvenes, quienes reportan no estar bajo ningún tipo de tratamiento, universitarios y de nacionalidad argentina. A partir del análisis de Mapeo Cerebral basado en el cálculo de Transformadas de Fourier, fue posible tipificar la actividad cerebral que corresponde a las dos tareas mencionadas. Con estos resultados será posible determinar si el diseño experimental, metodología e instrumentos utilizados son coherentes y viables para continuar con los mismos lineamientos o modificarlos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242231,"idioma_id":5,"titulo":"Perfiles de actividad eléctrica cortical Beta 3 en tareas de cálculos matemáticos sencillos e imaginación de objetos. Un estudio descriptivo","resumen":"En el presente estudio se muestran los patrones grupales de activación cortical registrados por un electroencefalógrafo digital, de 21 canales, durante la resolución de cálculos matemáticos y la evocación imaginaria de objetos en sujetos jóvenes, quienes reportan no estar bajo ningún tipo de tratamiento, universitarios y de nacionalidad argentina. A partir del análisis de Mapeo Cerebral basado en el cálculo de Transformadas de Fourier, fue posible tipificar la actividad cerebral que corresponde a las dos tareas mencionadas. Con estos resultados será posible determinar si el diseño experimental, metodología e instrumentos utilizados son coherentes y viables para continuar con los mismos lineamientos o modificarlos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242232,"idioma_id":5,"titulo":"´Que la universidad se pinte de feminismos´ para enfrentar las violencias sexistas","resumen":"Este artículo se presenta en la seccióm intervención polémica para abordar una realidad reciente en algunas de las universidades nacionales como es la implementación de los protocolos de violencia de género. En una reflexión, madurada a través de la experiencia y la articulación conceptual, proponemos captar la complejidad de la temática así como la necesaria apuesta política que significa la existencia e implementación de estos instrumentos en las instituciones de educación superior.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242233,"idioma_id":5,"titulo":"Feminismos y ciencias sociales. Propuestas pedagógicas y aportes críticos para revisar programas de formación en el grado.","resumen":"En este trabajo presentamos los avances producidos en el marco del proyecto de investigación Feminismo y Ciencias Sociales: procedencias, inserciones y carencias en el diseño curricular, que tiene el propósito de problematizar los enfoques teórico-epistemológicos predominantes en las propuestas académicas de formación en ciencias sociales. Como parte de las tareas de investigación propusimos revisar los programas de asignaturas correspondientes a las licenciaturas en Ciencia Política, Comunicación Social, Relaciones Internacionales y Trabajo Social que se imparten en la Facultad de Ciencia Política y Relaciones Internacionales (RR. II.) de la Universidad Nacional de Rosario (UNR). Esta se tradujo en una propuesta pedagógica desarrollada junto lxs estudiantes que cursan la unidad electiva Introducción a la Perspectiva de Género en la misma Facultad. Aquí reflexionamos sobre los resultados de este ejercicio investigativo revisando las categorías hegemónicas que están presentes en los programas elaborados para la formación de profesionales cuyos perfiles se orientan a investigar, planificar, intervenir en diversos ámbitos y situaciones sociales, y nos preguntamos por las ausencias que imposibilitan reconocer los condicionamientos estructurales de un sistema patriarcal y heterosexista dónde el género y la sexualidad constituyen, junto con las posiciones de clase, étnicas-raciales, nacionales y generacionales, marcas que determinan las coordenadas de lxs sujetxs (ver nota 2) en las asimétricas relaciones de poder.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242234,"idioma_id":5,"titulo":"Igualdad de oportunidades y trabajo periodístico. Retos, retóricas y obstáculos","resumen":"Después de más dos décadas de la Conferencia de Beijing (1995), nos detenemos areflexionar sobre sus repercusiones actuales a nivel local, analizando los avances producidos en materia de derechos de acceso y participación de las mujeres en los medios de comunicación argentinos. En este trabajo interesa revisar, apoyándonos en las teorías criticas feministas, el principio de igualdad de oportunidades incluido en declaraciones y plataformas de acción que emanan de los organismos internacionales, observando sus limitaciones simbólicas y materiales en la configuración de acciones que fomenten la participación equilibrada de mujeres y varones en los medios de comunicación. Asimismo, recorremos aspectos del problema de las desigualdades generizadas observados, previamente, en espacios de producción periodística, tomados aquí como objeto de indagación y ejemplo generalizable a otros ámbitos, porque entendemos que la efectividad de medidas de igualdad como éstas, solo puede calibrarse al contrastar los efectos reales en ámbitos situados y a la luz de las experiencias laborales y de relaciones de poder que allí se desarrollan.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242235,"idioma_id":4,"titulo":"Reporte y resolución de complicaciones intraoperatorias durante castraciones masivas en perras y gatas realizadas en un quirófano móvil en el sur de la Provincia de Santa Fe","resumen":"En este artículo se describe el protocolo quirúrgico que llevó a cabo un equipo de profesionales de la Cátedra de Cirugía  de la Facultad de Ciencias Veterinarias de Casilda (Universidad Nacional de Rosario) para realizar castraciones masivas en perras y gatas utilizando como vía de abordaje la flancotomía; se reportan las complicaciones intraoperatorias halladas y se detallan las estrategias que se utilizaron para resolverlas.En un total de 929 castraciones realizadas en el período 2014-2015, se constató que las complicaciones más frecuentes fueron úteros con contenido (piometras, mucómetras, hemómetras y preñez). Se concluye que, debido a los inconvenientes que generan las complicaciones intraquirúrgicas en el desarrollo del protocolo quirúrgico y en los posibles desvíos en los resultados esperados, los profesionales que integran el equipo quirúrgico deben contar con las competencias necesarias y la experiencia suficiente para solucionarlas con presteza, sin poner en riesgo el bienestar animal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242236,"idioma_id":5,"titulo":"Diseño de un instrumento para evaluar exámenes finales orales en una cátedra de Cirugía de la Carrera de Médico Veterinario: una experiencia realizada","resumen":"En este artículo se describe una planilla utilizada como instrumento para evaluar los exámenes finales orales de la asignatura Cirugía en la carrera de Medicina Veterinaria de la Universidad Nacional de Rosario. La planilla guía y ordena el trabajo de los docentes con el fin de alcanzar criterios de evaluación más homogéneos entre los miembros de un tribunal examinador, minimizar el impacto de la subjetividad sobre la calificación final del examen y obrar como herramienta práctica para orientar y formar a los docentes noveles en la difícil y cotidiana tarea de evaluar.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242238,"idioma_id":4,"titulo":"Contributions to group work and to the management of collective processes in extension and rural development","resumen":"Working with farmers´ groups, associations and cooperatives constitutes a fundamental element of extension work with family farmers. Despite the fact that extension practitioners face many problems in this area of their work, there is currently a lack of academic literature that systematically addresses the topic and offers concrete guidelines for practice. Thus, this paper will aim to clarify the benefits of farmers´ groups, associations and networks within the context of family farming, systematise problems faced by rural extensionists when working with farmers´ groups and associations, provide conceptual tools for understanding group and associative processes, and construct a set of guidelines and recommendations for facing said problems. In order to achieve these aims, the authors conducted an extensive literature review and drew upon their personal experience on the topic.Results suggest that some of the benefits of associative work are: better access to inputs, produce and credit markets, the facilitation of learning processes, the empowerment of family farmers as social actors, and a reduction of rural extension costs. Additionally, with respects to the problems faced by extensionists, the following can be highlighted: individualist attitudes and conflicts between farmers, scarce participation and commitment, problems with leaderships and with organisations´ administrative management, and the lack of extensionists´ training to address these processes, among others. With regards to the factors that increase trust and cooperation are: interpersonal communication and mutual knowledge, sharing problems, values and objectives, and the existence of shared rules for the functioning of the group that include sanctions for transgressors. In this context, the extensionists´ role will be that of facilitating processes of construction of group relationships, creating rules for the groups´ functioning and developing the group´s capacities for self-management.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242239,"idioma_id":4,"titulo":"Towards a new paradigm for rural extensionists&rsquo; in-service training","resumen":"Changes in the conceptions of extension and rural innovation, as well as the persistence of diffusionist extension approaches, require rethinking training strategies for rural extensionists. Drawing upon conceptual insights pertaining to the theory of action, the social learning theory, and the communities of practice framework, in this paper, current training and educational strategies for extensionists will be critically reflected upon, lessons learnt will be extracted, and proposals will be generated. Amongst them, the need for expanding and reframing what we understand ?training extensionists? to be, overcoming the traditional transfer-of-knowledge approach, focusing on the reflection on practice process, supporting the horizontal exchange of knowledge and experiences, and facilitating the development of extensionist communities of practice, are highlighted. Finally, it is argued that there is a need for advancing the conceptual discussion, systematizing innovative training practices, and researching trainings for extensionists and their impact.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242242,"idioma_id":5,"titulo":"BULLYING Y CIBERBULLYING: UN ESTUDIO COMPARATIVO CON ADOLESCENTES ESCOLARIZADOS","resumen":"Los estudios sobre bullying y ciberbullying realizados en nuestro medio resultan insufi cientes para comprender y prevenir estos fenómenos. En la presente investigación se propuso analizar las diferencias en bullying y ciberbullying en relación al tipo de gestión escolar (pública o privada), el sexo y la edad. En esta investigación descriptiva, comparativa y de corte transversal se administró el test Cyberbullying a 3,500 adolescentes entre 11 y 20 años. Los resultados mostraron que los estudiantes disponen de mayor cantidad de aparatos con conexión a internet en escuelas privadas y mayor cantidad de ciberobservadores. En relación al sexo, los varones asumen más el rol de agresores en bullying y ciberbullying. En referencia a la edad, se halló que los más jóvenes tendían a informar más el rol de víctima de bullying, mientras que los mayores, el rol de observador de ambas conductas. El debate se centra en la presencia del acoso en todas las escuelas, sin diferenciar entre públicas y privadas","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242248,"idioma_id":5,"titulo":"Determinación de cloro activo en diferentes soluciones de hipoclorito de sodio","resumen":"El hipoclorito de sodio, en sus diferentes concentraciones, constituye la primera elección como sustancia irrigadora de los conductos radiculares. Es por esto la importancia de mantener las concentraciones para obtener una buenadesinfección El objetivo de este estudio fue determinar la cantidad de cloro activo presente en diferentes marcas comerciales de hipoclorito de sodio.Se seleccionaron diferentes marcas comerciales de hipoclorito de sodio, la evaluación del cloro activo se realizó mediante el método titulación de óxido-reducción. El 100% de las marcas comerciales no presentó la cantidad de cloro activo declarada por el fabricante (46,6 +\/15,68), en todas las muestras analizadas en laboratorio los resultados obtenidos fueron menores (39,57 +\/12,14) a los especificados por el fabricante con una diferencia estadísticamente significativa (p < 0.01)Esta investigación permite evaluar un aspecto relevante dentro del campo de la terapia endodóntica, mejorando los estándares de calidad de las prácticas clínicas.ABSTRACTSodium hypochlorite, at different concentrations, is the first choice as substance irrigating root canals. That is why the importance of maintaining concentrations to obtain good disinfection The aim of this study was to determine the amount of active chlorine in different brands of sodium hypochlorite. different brands of sodium hypochlorite were selected, evaluation of active chlorine was performed by redox method. The 100% trademarks not presented the amount of active chlorine declared by the manufacturer(46.6 + \/ 15.68) in all samples analyzed in the laboratory results obtained were lower (39.57 + \/ 12.14) to those specified by the manufacturer with a statistically significant difference (p <0.01). This research evaluates a relevant aspect within the field of endodontic therapy, improving thequality standards of clinical practice.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242249,"idioma_id":4,"titulo":"Observations of the First Electromagnetic Counterpart to a Gravitational-wave Source by the TOROS Collaboration","resumen":"We present the results of prompt optical follow-up of the electromagnetic counterpart of the gravitational-wave event GW170817 by the Transient Optical Robotic Observatory of the South Collaboration. We detected highly significant dimming in the light curves of the counterpart (&#916;g = 0.17 ± 0.03 mag, &#916;r = 0.14 ± 0.02 mag, &#916;i = 0.10 ± 0.03 mag) over the course of only 80 minutes of observations obtained &#8764;35 hr after the trigger with the T80-South telescope. A second epoch of observations, obtained &#8764;59 hr after the event with the EABA 1.5 m telescope, confirms the fast fading nature of the transient. The observed colors of the counterpart suggest that this event was a 'blue kilonova' relatively free of lanthanides.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242250,"idioma_id":5,"titulo":"Determinación de cloro activo en diferentes soluciones de hipoclorito de sodio","resumen":"El hipoclorito de sodio, en sus diferentes concentraciones, constituye la primera elección como sustancia irrigadora de los conductos radiculares. Es por esto la importancia de mantener las concentraciones para obtener una buena desinfección El objetivo de este estudio fue determinar la cantidad de cloro activo presente en diferentes marcas comerciales de hipoclorito de sodio.Se seleccionaron diferentes marcas comerciales de hipoclorito de sodio, la evaluación del cloro activo se realizó mediante el método titulación de óxido-reducción. El 100% de las marcas comerciales no presentó la cantidad de cloro activo declarada por el fabricante (46,6 +\/15,68), en todas las muestras analizadas en laboratorio los resultados obtenidos fueron menores (39,57 +\/12,14) a los especificados por el fabricante con una diferencia estadísticamente significativa (p < 0.01)Esta investigación permite evaluar un aspecto relevante dentro del campo de la terapia endodóntica, mejorando los estándares de calidad de las prácticas clínicas.ABSTRACTSodium hypochlorite, at different concentrations, is the first choice as substance irrigating root canals. That is why the importance of maintaining concentrations to obtain good disinfection The aim of this study was to determine the amount of active chlorine in different brands of sodium hypochlorite. different brands of sodium hypochlorite were selected, evaluation of active chlorine was performed by redox method. The 100% trademarks not presented the amount of active chlorine declared by the manufacturer (46.6 + \/ 15.68) in all samples analyzed in the laboratory results obtained were lower (39.57 + \/ 12.14) to those specified by the manufacturer with a statistically significant difference (p <0.01). This research evaluates a relevant aspect within the field of endodontic therapy, improving the quality standards of clinical practice.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242251,"idioma_id":5,"titulo":"Aquí no pasó nada. El diablo está en lo particular.","resumen":"Esta narración forma parte de una serie de relatos ásperos sobre pasados inacabados y truncos. Urdimbres, a la espera de la trama. Hilando, intentamos valernos de esos momentos que vienen, en forma fragmentaria, a recordarnos que hablamos de violencias sobre violencias.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242252,"idioma_id":5,"titulo":"Aceptación social y estrategias de solución de problemas interpersonales en niños en edad escolar.","resumen":"El objetivo del presente proyecto es analizar las relaciones entre el estatus sociométrico y las estrategias de solución de problemas interpersonales en niños en edad escolar. Se entiende el estatus sociométrico escolar como el grado en el que el niño es aceptado o rechazado por sus iguales. La aceptación social por parte de los pares requiere de ciertas habilidades y experiencia, para poder responder de manera adecuada al entorno social. La habilidad cognitiva de solución de problemas interpersonales refiere a la capacidad de generar conductas que apunten a resolver los problemas que se plantean en una situación interpersonal. Se trata de un proceso que requiere, entre otras habilidades, de la capacidad de generar mentalmente diferentes estrategias de solución que puedan ser utilizadas para resolver un mismo problema. El estudio se corresponde con un diseño descriptivo de tipo ex post facto retrospectivo con dos grupos (alta y baja aceptación sociométrica). Se utilizará el test sociométrico en el aula y el test Evhacospi de manera individual, una vez conformados los grupos. Se espera que los resultados permitan ampliar la información en este campo, como así también desarrollar estrategias de intervención para mejorar las relaciones interpersonales de los niños en el contexto escolar.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242253,"idioma_id":4,"titulo":"Combining user preferences and expert opinions: a criteria synergy-based model for decision making on the Web","resumen":"Customers strongly base their e-commerce decisions on the opinions of others by checking reviews and ratings provided by other users. These assessments are overall opinions about the product or service and it is not possible to establish why they perceive it as good or bad. To understand this ?why?, it is necessary an expert?s analysis concerning the relevant factors of the product or service. Frequently, these two visions are not coincident and the best product for experts may not be the best one for users. For this reason, trustworthy decision making methods that integrate the mentioned views are highly desirable. This article proposes a multi-criteria decision analysis model based on the integration of users? preferences and experts? opinions. It combines the majority?s opinion and criteria synergy to provide a unified perspective in order to support consumers? ranking-based decisions in social media environments. At the same time, the model supplies useful information for managers about strengths and weaknesses of their product or service according to users? experience and experts? judgment. The aggregation processes and synergy criteria are modeled in order to obtain an adequate consensus mechanism. Finally, in order to test the proposed model, several simulations using hotel valuations are performed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242261,"idioma_id":5,"titulo":"Wilhelm Röpke y la espiritualidad del neoliberalismo","resumen":"¿Qué entendemos hoy por 'neoliberalismo'? Si bien hay varias formas de contestar tal pregunta, la respuesta más frecuente consiste en asociarlo con la aplicación de un conjunto de medidas estrictamente económicas; de hecho, se dice que los neoliberales, casi por defecto congénito, no pueden pensar la realidad más allá de los números y las recetas abstractas. Siguiendo el método arqueológico-genealógico de Michel Foucault y de algunos de sus intérpretes contemporáneos, el presente artículo buscará revisar y en lo posible ampliar aquella concepción crítica. Nuestra hipótesis es que el neoliberalismo no se reduce a un mero 'economicismo', sino que contiene más bien toda una dimensión 'espiritual'; todo un campo de prácticas y de discursos que se conforma como respuesta ante el excesivo racionalismo de las sociedades modernas. La cuestión consiste en transformar a los hombres desde dentro, hasta el punto de tornarlos más aptos para acceder a un conjunto de valores y asimilar ciertas formas de comportamiento. Según sostiene este artículo, es en los escritos de Wilhelm Röpke, un economista y sociólogo alemán de mediados del siglo XX, donde mejor se aprecia la dimensión espiritual del neoliberalismo. Röpke proponía un 'diagnóstico' y una 'terapéutica'. El primero sostiene que los hombres padecen una enfermedad espiritual denominada como 'masificación' y 'proletarización', mientras que la terapéutica procura hacer de esos hombres unos emprendedores de sí mismos. Tal sería el modo de superar los efectos adversos del capitalismo: transformando a los hombres masificados y proletarizados en sujetos completamente comprometidos con su profesión. No se trata sencillamente de recuperar un pensamiento casi olvidado por la historia, sino de explorar los límites de nuestro presente, especialmente de nuestras formas de subjetividad. Aunque muchas de las críticas contemporáneas no hayan reparado aún en ello, hay que preguntarse hasta qué punto los diagnósticos y las terapéuticas propuestas por neoliberales como Röpke persisten en la actualidad. Aquí no se darán respuestas tajantes y definitivas, pero sí algunos indicios al respecto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242262,"idioma_id":4,"titulo":"Glyphosate and Aminomethylphosphonic acid (AMPA) contents in the respirable dust emitted by an agricultural soil of the central semiarid region of Argentina","resumen":"One environmental issue in the semiarid Pampas of Argentina and elsewhere is the possible accumulation of glyphosate [N-(phosphonomethyl) glycine] and aminomethylphosphonic acid (AMPA, the main metabolite of the microbial degradation of glyphosate) in the dust emitted by agricultural soils. However, there are not glyphosate and AMPA concentration measurements in the respirable dust emitted by the bulk soils and its different aggregate-size fractions. The aim of this study was to determine, for an agricultural soil of the central semiarid region of Argentina, the concentrations of glyphosate and AMPA in the respirable dust emitted by the bulk soil and its aggregate-size fractions. The study was carried in Santa Rosa La Pampa (S36° 46´; W64° 16´; 210 m a.s.l.) in a plot where glyphosate was not used in the last 12 months. Soil samples were air dried and sieved by 2 mm (bulk soil) and with a rotary sieve to separate the following aggregate-size fractions:  19.2 mm. The Easy Dust Generator (EDG) was used to generate dust from different sources (the bulk soil and its aggregate-size fractions. The respirable dust was collected using an electrostatic precipitator (C&L model number GH-939) coupled to EDG. Organic matter (OM), particle size composition, glyphosate and AMPA were determined in the Sources and the respirable dust emitted by them. Results showed that OM and clay contents were different among Sources but similar in the respirable dust emitted by the different Sources. Glyphosate content varied between 1 and 3 ppb in the Sources and between 11.0 and 19.5 ppb in the respirable dust. AMPA content ranged from 80 and 150 ppb in the Sources and from 520 to 750 ppb in respirable dust. AMPA contents were higher than those of glyphosate in both, the Sources and respirable dust because the longer AMPA persistence in the soil. Enrichment ratios (ERs, quotient between concentration in respirable dust and Sources) for OM, clay, glyphosate and AMPA were higher than 1, showing that respirable dust was enriched in all these compounds. ERs for glyphosate and AMPA varied between 4 and 17 and they were higher than ERs for clay and OM which varied between 1 and 3. This indicates that glyphosate and AMPA are accumulated in the respirable dust more than clay and OM. Our results suggest that respirable dust emitted by agricultural soils can be contaminated with that herbicide and its main metabolite even 12 months after the last glyphosate application. Further studies are needed in order to assess glyphosate and AMPA in different soil classes under different land uses. Their effect on health and in the environment should also be evaluated.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242263,"idioma_id":5,"titulo":"Alejandría y el multiculturalismo: nuevas líneas de investigación en los estudios patrísticos","resumen":"Ciner, P.; Fernández, P.; Pons, L. y otros, Alejandría y el multiculturalismo: nuevas líneas de investigación en los estudios patrísticos, Revista Cuadernos de Ciencia y Espiritualidad. Universidad Católica de Cuyo. (en prensa)","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242265,"idioma_id":5,"titulo":"La reflexión de los docentes en la enseñanza de las cienciasen primaria","resumen":"Esta investigación es un estudio de casos que hace eje en el análisis de las propiasprácticas como una competencia profesional crucial. El proceso supone un recorrido a través dedistintas etapas en un dispositivo de análisis que integra entrevistas previas, videograbaciones declases e instancias de autoconfrontación con episodios filmados de la propia actividad de enseñanza.Los resultados muestran, por un lado, bajos niveles reflexivos y, por otro, la integración dedimensiones morales y de naturalización del conocimiento escolar. Ambas evidencias suponenfuertes obstáculos en la enseñanza de las ciencias en primaria1.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242266,"idioma_id":4,"titulo":"Statistical mechanical modeling of the transition Stage II &#8594; Stage I of Li-ion storage in graphite. A priori vs induced heterogeneity","resumen":"An improved model to analyze the partial molar entropy step between stage II and stage I for lithium intercalation in graphite, based in statistical mechanics, is presented. At difference with our previous formulation, which assumed a priori heterogeneities, the present model considers the more realistic case of induced heterogeneities. The present work shows that, similarly to considerations made in the literature with intercalation cathode materials, most of the partial molar entropy changes for Li insertion into graphite may be explained on a configurational basis.The interaction between ions intercalated in a same layer of graphite can be inferred to be strongly attractive, as was assumed in the literature for the simulation of voltammetric profiles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242267,"idioma_id":4,"titulo":"Penicillium brevicompactum causing bulb rot on Hyppeastrum x hybridum in Argentina","resumen":"In July 2015, bulbs of Hippeastrum x hybridum imported for cultivation in Buenos Aires (Argentina) showed loss of firmness, rot and green mold. Small pieces from the edge of the lesions were surface disinfected with 2% sodium hypochlorite for 90 sec, rinsed in sterilized distilled water and incubated on potato dextrose agar at 22ºC. Isolates of Penicillium brevicompactum Dierckx (Raper and Tom, 1968) were consistently obtained, and one of them coded NTA-IF-502 was chosen to confirm pathogenicity. Healthy, unwounded and needle-punctured bulbs were immersed for 1 minute in suspensions of 1.4 x 106 conidia mL-1 while bulbs immersed in sterilized water served as controls. The bulbs were individually planted in pots filled with a sterile substrate, and enclosed in polyethylene bags for three days. After 45 days, all the inoculated plants showed yellowish foliage and loss of turgidity. Ten days after, the plants from inoculated punctured bulbs had died and those from inoculated unwounded bulbs showed an advanced wilt. Rotten bulbs and roots and green mold were observed on inoculated plants eased out of the pots. Controls remained healthy. The pathogen was successfully recovered from infected organs. The morphological identification was confirmed by DNA sequence data of the ß-tubulin gene (GenBank accession No. KY216143). This finding represents the first record of this pathogenic species associated with bulb rot of Hippeastrum x hybridum in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242269,"idioma_id":5,"titulo":"Don Juan Tenorio en el espejo. Notas a la obra ?El Hermano Juan? de Miguel de Unamuno a partir de un nuevo rasgo constitutivo del personaje: la conciencia de sí mismo","resumen":"El artículo aborda el análisis de la obra El Hermano Juan o el mundo es teatro (1934) de Miguel de Unamuno. La imagen arquetípica de don Juan Tenorio ?heredada de Tirso- presenta un giro en la versión de Zorrilla, quien lo hace enamorarse. Con ello el personaje pierde parte de su valor arquetípico, aunque gana en humanidad. Unamuno, años después, le incorpora una nueva característica, que provoca otra innovación: lo hace un personaje excesivamente preocupado por suexistencia, un personaje reflexivo, centrado en el reconocimiento de sí mismo. Esta revelación, esta anagnórisis, altera su conducta. Si Maeztu ha considerado que el haberse enamorado ha constituido una tragedia para el personaje en tanto arquetipo, el reconocimiento de sí que Unamuno le aporta podría entenderse como la segunda tragedia que sufre el personaje, opinión que se intenta sostener en el artículo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242273,"idioma_id":4,"titulo":"A new spectral sequence for homology of posets","resumen":"We develop a new method to compute the homology groups of Alexandroff topological spaces (or equivalently of partially ordered sets) by means of spectral sequences giving a complete and simple description of the corresponding differentials. Applying our tools, we obtain a generalization of a result of Minian in homological Morse theory for posets.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242275,"idioma_id":5,"titulo":"Desarrollo de un simulador para la práctica de maniobras quirúrgicas básicas","resumen":"El objetivo de este artículo es describir el diseño y la construcción de un simulador que utiliza la Cátedra de Cirugía para la enseñanza de técnicas básicas de suturas y anudamientos. El mismo, se construyó empleando un trozo de caño de policloruro de vinilo (PVC) envuelto con un rectángulo de polímero termoplástico a base de etillvinilacetato (goma Eva). De acuerdo a las observaciones realizadas, este simulador ha resultado ser económico, de muy fácil construcción y reutilizable, ya que la faja de polímero se puede ir girando hasta su completa utilización para luego cambiarla. La limpieza es simple y el almacenamiento no requiere mayores cuidados. El costo de realización es bajo, por lo cual se puede tener un simulador para cada alumno. Como desventaja se puede decir que el polímero no se comporta con la misma elasticidad y resistencia que los tejidos vivos, no obstante, el alumno puede manipular el instrumental quirúrgico en forma correcta, tanto para realizar las maniobras de diéresis y exéresis, como para practicar en repetidas oportunidades los distintos puntos de sutura (simples  y continuos) y las distintas técnicas de anudamientos (manuales e instrumentales). Además, desde el punto de vista espacial, el simulador evita que el aprendiz trabaje sobre una superficie plana, permitiendo que durante la realización de la sutura se manipulen los bordes de la incisión de una manera similar a la realidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242278,"idioma_id":5,"titulo":"Descripción de una maqueta para la enseñanza de las técnicas de ovariectomía y ovariohisterectomía en la perra. Una experiencia realizada","resumen":"La práctica y experiencia directa sobre modelos de simulación, permite al alumno realizar un proceso de aprendizaje vivencial. Este proceso impulsa al alumno a involucrarse y participar, reflexionar sobre lo acontecido en forma crítica, extraer sus propias conclusiones e incorporar lo aprendido.Los modelos de maquetas y biosimuladores permiten repetir intensivamente los procedimientos, hasta lograr el pleno dominio de los mismos sin riesgos para los pacientes, además posibilita la autoevaluación y corrección, es decir que al tratarse de dispositivos, permite reconocer errores y realizar un seguimiento para la autoevaluación y corrección de los mismos. En este artículo se describe el uso de un modelo de maqueta para la enseñanza de la ovariectomía en caninos y felinos, diseñado y fabricado por los integrantes de la Cátedra de Cirugía II de la Facultad de Ciencias Veterinarias de Casilda.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242280,"idioma_id":4,"titulo":"Pectinase production by Aspergillus giganteus in solid-state fermentation: optimization, scale-up, biochemical characterization and its application in olive-oil extraction","resumen":"The application of pectinases in industrial olive-oil processes is restricted by its production cost. Consequently, new fungal strains able to produce higher pectinase titers are required. The aim of this work was to study the capability of Aspergillus giganteus NRRL10 to produce pectinolytic enzymes by SSF and evaluate the application of these in olive-oil extraction. A. giganteus was selected among 12 strains on the basis of high pectinolytic activity and stability. A mixture composed by wheat bran, orange, and lemon peels was selected as the best substrate for enzyme production. Statistical analyses of the experimental design indicated that pH, temperature, and CaCl2 are the main factors that affect the production. Subsequently, different aeration flows were tested in a tray reactor; the highest activity was achieved at 20 L min&#8722;1 per kilogram of dry substrate (kgds). Finally, the pectinolytic enzymes from A. giganteus improved the oil yield and rheological characteristics without affecting oil chemical properties.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242284,"idioma_id":5,"titulo":"Política y políticas de la UNASUR: institucionalidad y desafíos políticos","resumen":"El trabajo explora tres dimensiones centrales de la UNASUR. Por un lado, el desempeño y el papel que hasta la actualidad este organismo ha jugado en relación a las conflictividades y a la defensa de la democracia en la región. Para ello, se analizan las acciones e intervenciones del organismo que han redundado en beneficio del mantenimiento de la paz en Sudamérica. En segundo lugar, el trabajo aborda la agenda de problemas y acciones de su órgano ejecutivo, la Secretaría General, de forma tal de evidenciar sus ejes de trabajo y evolución de sus asuntos de políticas. Por último, el trabajo indaga el papel destacado que ocupa en su funcionamiento la integración en materia de infraestructura y los avances y desafíos que se le presentan al organismo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242285,"idioma_id":4,"titulo":"Hydrogenation of diacetyl over composite supported egg-shell noble metal catalysts","resumen":"Two Composite supports with a mixed inorganic-organic structure were synthesized:  BTAl and UTAl. Hydrophilic-hydrophobic dual properties of the supports were suitable for preparing egg-shell supported metal catalysts for selective hydrogenation reactions.The catalysts were characterized by ICP, XRD, OM, TEM, EPMA, XPS and TGA. Their mechanical resistance was assessed. Activity and selectivity were tested with the hydrogenation of 2,3-butanedione (diacetyl) to 3-hydroxy-2-butanoneacetoin (acetoin).The same order of increasing metal particle size was found for the two tested supports:  Pt < Ru < Pd. The XPS analysis showed that the metal\/Composite catalysts reduced in H2 at 503 K had two kinds of active sites: reduced (Me°) and electron-deficient (Me+). It was rationalized that the hydrogen bond cleavage was performed on the Me° active sites, while reactant adsorption occurred on the Me+ sites. The differences in activity and selectivity between the Composite catalystswere attributed to electronic effects on the different metals and to different adsorptive properties of the different polymers. The high selectivity to acetoin was attributed to the preferential adsorption of diacetyl as compared to the adsorption of acetoin.The BTAl catalysts were slightly more active and selective than the UTAl ones. This was attributed to electronic effects caused by remnant organic groups on the Composite supports (urethane or biphenyl on UTAl or BTAl, respectively).  Pd-BTAl was the most active and selective catalyst, a fact related to electronic effects of both palladium and the support.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242286,"idioma_id":4,"titulo":"'Pt and Pd on activated carbon for oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid'","resumen":"The liquid phase transformation of 5-hydroxymethylfurfuraldehyde (5-HMF) towards 2,5-furandicarboxylicacid (2,5-FDCA) using Pt and Pd catalysts supported on activated carbon and with the presence of CaCO3 andNaOH, is reported. The catalysts were characterized using different techniques, such as: H2 chemisorptionat room temperature, X ray photoelectronic spectroscopy (XPS) and thermogravimetric analysis (TGA).The results indicate that the particle size followed the order: PtCl\/C < PdCl\/C < PdN\/C, which is closelyrelated to the catalytic behavior. It was found that the metal particles are present in the Pd0 and Pt0 form.PtCl\/C was most active catalyst using CaCO3 as weak base.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242287,"idioma_id":4,"titulo":"More active and sulfur resistant bimetallic Pd-Ni catalysts","resumen":"The influence of the kind of metal precursor and the sequence of impregnation on the properties of Pd-Ni catalysts was evaluated during the test reaction of selective hydrogenation of styrene to ethylbenzene by means of physicochemical characterization. The focus was put on the final hydrogenating activity and the resistance to deactivation by sulfided compounds (thiophene).  The used techniques of characterization were ICP, XPS, XDR, TPR, CO chemisorption and TEM. XPS results indicated the presence of different Pd species: Pd&#948;-, Pd0 and Pd&#948;+.  In the case of the Ni containing catalysts, Ni0 and NiO species were also detected.  These palladium and nickel species would be responsables of the variation of activity and sulfurresistance of the catalysts.  NiClPd catalysts had a higher resistance to deactivation by sulfur poisoning.  This was associated to a higher concentration of Pd&#61544;+ClxOy species that would prevent the adsorption of thiophene by both steric and electronic effects.  It could also be due to the lower concentration of Pd0 and Ni0 on these catalysts, as compared to those shown by the PdNiCl catalysts.  Both the Pd0 and Ni0 species are more prone to poisoning because of their higher electronic availability.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242289,"idioma_id":4,"titulo":"Improved multiclass feature selection via list combination","resumen":"Feature selection is a crucial machine learning technique aimed at reducing the dimensionality of the input space. By discarding useless or redundant variables, not only it improves model performance but also facilitates its interpretability. The well-known Support Vector Machines--Recursive Feature Elimination (SVM-RFE) algorithm provides good performance with moderate computational efforts, in particular for wide datasets. When using SVM-RFE on a multiclass classification problem, the usual strategy is to decompose it into a series of binary ones, and to generate an importance statistics for each feature on each binary problem. These importances are then averaged over the set of binary problems to synthesize a single value for feature ranking. In some cases, however, this procedure can lead to poor selection. In this paper we discuss six new strategies, based on list combination, designed to yield improved selections starting from the importances given by the binary problems. We evaluate them on artificial and real-world datasets, using both One--Vs--One (OVO) and One--Vs--All (OVA) strategies. Our results suggest that the OVO decomposition is most effective for feature selection on multiclass problems. We also find that in most situations the new K-First strategy can find better subsets of features than the traditional weight average approach.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242292,"idioma_id":4,"titulo":"Toxicological, enzymatic, and molecular assessment of the insecticide susceptibility profile of triatoma infestans (Hemiptera: Reduviidae, Triatominae) populations from rural communities of Santa Cruz, Bolivia","resumen":"A wide range of insecticide resistance profiles has been reported across Bolivian domestic and sylvatic populations of Triatoma infestans (Klug, 1834) (Hemiptera, Reduviidae), including some with levels proven to be a threat for vector control. In this work, the insecticide profile of domestic T. infestans was studied with standardized toxicological bioassays, in an area that has not undergone consistent vector control. F1 first-instar nymphs hatched in laboratory from bugs captured in three communities from the Santa Cruz Department were evaluated with different insecticides. Moreover, the enzymatic activity of esterases and cytochrome P450 monooxygenases was measured in individual insects to evaluate the possible mechanism of metabolic resistance to pyrethroids. In addition, the DNA sequence of sodium channel gene (kdr) was screened for two point mutations associated with pyrethroid resistance previously reported in T. infestans. All populations showed reduced susceptibility to deltamethrin and &#945;-cypermethrin, albeit the RR50 values varied significantly among them. Increased P450 monooxygenases and permethrate esterases suggest the contribution, as detoxifying mechanisms, to the observed resistance to deltamethrin in all studied populations. No individuals presented either mutation associated to resistance in the kdr gene. The level of susceptibility to &#945;-cypermethrin, the insecticide used by the local vector control program, falls within an acceptable range to continue its use in these populations. However, the observed RR50 values evidence the possibility of selection for resistance to pyrethroids, especially to deltamethrin. Consequently, the use of pyrethroid insecticides should be closely monitored in these communities, which should be kept under entomological surveillance and sustained interventions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242296,"idioma_id":4,"titulo":"Intercalation stage dependence of core electronic excitations in Li-intercalated graphite from inelastic X-ray scattering","resumen":"Li and C 1s core-electron excitation spectra of electrochemically prepared stage-II and stage-I lithiated graphite were investigated by means of inelastic X-ray scattering spectroscopy. The near-edge structure is discussed, and the spectral features are interpreted using ab initio calculations. Our results confirm the invariance of the excitation threshold for transitions from C 1s core-states to empty &#960;&#8727; states upon Li intercalation for stage-I and show this invariance also occurs for the second stage of intercalation. A systematic shift of the &#963;&#8727; excitation threshold to lower energies with the Li content was observed. The Li core spectra reveal an ionic character of the intercalated Li in stage-I and in stage-II. The present results provide further valuable information for forthcoming in situ studies of lithiation\/delithiation processes in graphite anodes by inelastic X-ray scattering spectroscopy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242297,"idioma_id":4,"titulo":"Lithium dual uptake anode materials: crystalline Fe 3 O 4 nanoparticles supported over graphite for lithium-ion batteries","resumen":"Graphite, the usual anode material for current technology of lithium ion batteries (LIB), has great advantages and its processing is widely known and industrially feasible. For improving the anode?s capacity, recent research has focused in using nano-carbons as an overcoming strategy rather than including cheap, conversion-type oxide metals. Here, we present the application of in-situ synthesized hybrid LIB active anode materials composed of magnetite nanoparticles (Fe3O4 NPs) and graphite of different sizes. The results show that the graphite's flake size plays an important role in the Fe3O4 NPs deposition and loading, and therefore in the morphology of the resulting laminate film. The electrochemical performance (evaluated by cyclic voltammetry, galvanostatic charge\/discharge cycles and impedance spectroscopy) is determined not only by the edge density of graphite flakes and Fe3O4 loading but also by the porosity of the anode films. The hybrid material electrode with smallest graphite particle size shows the highest reversible capacity of 845 mA h g&#8722;1, good rate capability and great cycling performance. This remarkable improvement in graphite?s capacity is reached by only adding 16 wt% of magnetite to the carbon material.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242300,"idioma_id":4,"titulo":"Characterization of small-spored Alternaria from Argentinean crops through a polyphasic approach","resumen":"Small-spored Alternaria have been isolated from a wide variety of food crops, causing both economic losses and human health risk due to the metabolites produced. Their taxonomy has been discussed widely, but no scientificconsensus has been established in this field to date. Argentina is a major exporter of agricultural products, so it is essential to thoroughly understand the physiological behaviour of this pathogen in a food safety context. Thus,the objective of this work was to characterize small-spored Alternaria spp. obtained from tomato fruits, pepper fruits, wheat grains and blueberries from Argentina by a polyphasic approach involving metabolomic and phylogenetic analyses based on molecular and morphological characters. Morphological analysis divided the population studied into three groups; A. arborescens sp.-grp., A. tenuissima sp.-grp., and A. alternata sp.-grp. However, when these characters were simultaneously analysed with molecular data, no clearly separated groupswere obtained. Haplotype network and phylogenetic analysis (both Bayesian and maximum parsimony) of a conserved region yielded the same result, suggesting that all isolates belong to the same species. Furthermore, no correlation could be established between morphological species-groups and a metabolite or group of metabolites synthesized. Thus, the whole set of analyses carried out in the present work supports the hypothesis that these small-spored Alternaria isolates from food belong to the same species. Identification at species level throughclassical morphology or modern molecular techniques does not seem to be a useful tool to predict toxicological risk in food matrices. The detection of any small-spored Alternaria from Section Alternaria (D.P. Lawr., Gannibal, Peever & B.M. Pryor 2013) in food implies a potential toxicological risk.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242301,"idioma_id":4,"titulo":"Resistance of Fusarium poae in Arabidopsis leaves requires mainly functional JA and ET signaling pathways","resumen":"Fusarium poae has been considered as a minor species among those that cause the FHB disease but in recent years several researchers have documented a high frequency of occurrence in several crops such as wheat and barley. Evaluating the interaction between Fusarium poae with the model plant Arabidopsis thaliana will contribute to the knowledge about plant defense against this pathogen. We evaluated the ability of F. poae to produce symptoms in Arabidopsis thaliana leaves by using two different methods. Moreover, we analyzed the defense of A. thaliana against F. poae using SA, JA and ET mutants and we monitored the expression level of genes involved in the main signaling pathways related to plant defense. Symptoms were observed in the inoculated leaves which allow demonstrating, as a first step, the ability of F. poae to infect A. thaliana leaves. Moreover, the results demonstrated that the npr1-1 mutants presented low symptoms compared to Col-0, etr2-1 and coi1-1 and that the coi1-1 mutant was the most susceptible genotypes followed by etr2-1 genotypes. The RT-PCR of several genes involved in plant defense revealed that PDF1.2, CHI\/PR3 and ERF1, three important JA-ET responsive genes and NPR1 and PR1, which are regulated by SA signaling, were expressed upon F. poae inoculation. Our results suggest that JA and ET could play a key role in Arabidopsis leaves defense against F. poae. Therefore, although SA responsive genes were expressed in the inoculated leaves compared to control, the low symptoms observed in npr1-1 mutants indicate that functional SA would not be required for plant defense to F. poae. In conclusion, our results represent the first evaluation of the response of the main A. thaliana phytohormones involved in plant defense in the presence of F. poae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242303,"idioma_id":4,"titulo":"New Vertebrates of the Brochero Formation (C&oacute;rdoba, Argentina): A Review of the Pliocene of Central Argentina","resumen":"The &ldquo;Horizonte Brocherense&rdquo; sensu Castellanos was created on the basis of a mammal assemblage recovered from the San Alberto Valley and Los Reartes Valley (C&oacute;rdoba, Argentina). This mammal association was placed in the &ldquo;Uquian Stage&rdquo; (early Pliocene) according to the stratigraphic scheme proposed by Castellanos in 1944. Later, different authors considered this association to belong either to the Montehermosan Stage\/Age (early Pliocene) or Huayquerian Stage\/Age (late Miocene), based on more updated stratigraphic schemes. Here, we present new vertebrates recovered from the type locality (San Alberto or Traslasierra Valley) of the Brochero Formation; we provide the first paleoenvironmental interpretation for this unit, and discuss the age of the fauna and its bearing sediments. As the main result, this work contributes to the knowledge of the Pliocene faunas, providing the first records of some anurans, snakes, and mammals for the Brochero Formation, and the biostratigraphic and chronological implications of such findings when comparing the fossil assemblage with its counterparts from South America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242304,"idioma_id":4,"titulo":"SYSTEMATIC REVISION AND EVOLUTIONARY HISTORY OF ACARECHIMYS PATTERSON IN KRAGLIEVICH, 1965 (RODENTIA, CAVIOMORPHA, OCTODONTOIDEA)","resumen":"The octodontoid rodent Acarechimys was abundant during the early Miocene and had the widest temporal and geographic distribution of any extinct caviomorph. Despite this extensive fossil record Acarechimys has not been well characterized. In this work, we systematically revise Acarechimys, describe new early?middle Miocene fossils from Argentina and Bolivia, corroborate its monophyly, and study its evolutionary history. Acarechimys has brachydont molars, retained deciduous premolars, four crests on upper molars, lowers with variably developed mesolophid and metalophulid II, and absence of mental foramen in the mandible. Acarechimys includes: Acarechimys leucotheae (late Oligocene, Chubut, Argentina), A. gracilis and A. constans (early Miocene, Chubut and Santa Cruz, Argentina), and A. minutus and A. minutissimus (early?middle Miocene of Patagonia Argentina, Bolivia, and Colombia). The temporal and geographic distributions suggest that Acarechimys could have evolved in Patagonia, by the early late Oligocene. Its acme was during the late early Miocene in Southern Patagonia. By the middle Miocene, Acarechimys decreased in diversity and was last recorded in high latitudes of South America (Patagonia). In lower latitudes, the oldest record is from the late early Miocene of Chucal, northern Chile, and during the late middle Miocene, the genus is recorded in localities of Colombia, Bolivia, and Peru. The available evidence suggests that Acarechimys would not be present in lower latitudes (N of ~ 30° S) before the early Miocene. The reasons Acarechimys dispersed northward at this time remain to be elucidated, but the timing coincides with a massive disappearance of other octodontoids from Patagonia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242305,"idioma_id":4,"titulo":"Mycoplasma bovis pneumonia in feedlot cattle and dairy calves in Argentina","resumen":"Mycoplasma bovis has emerged as an important cause of feedlot pneumonia in many countries. The aim of thispaper is to describe six cases of bovine Mycoplasma pneumonia in five different premises in Argentina. Gross examinationrevealed chronic bronchopneumonia with multiple foci of caseous necrosis. Microscopically, these contained a necroticcenter with abundant hypereosinophilic granular material surrounded by granulation tissue. Affected lung tested positive forM. bovis by immunohistochemistry and electron microscopy revealed membranous structures compatible with Mycoplasmaspp. To our knowledge, this is the first report of M. bovis pneumonia in Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242306,"idioma_id":4,"titulo":"IMPROVING IN THE ANTIBACTERIAL ACTIVITY AND THE ANTIOXIDANT PROPERTIES OF CHEMICALLY MODIFIED EXTRACTS OF ZINNIA PERUVIANA","resumen":"In the present work we investigate the changes in the antibacterial activity and the antioxidant properties of modified extracts of Zinnia peruviana (L.) L. campesterol, stigmasterol and &#946;-sitosterol were identified as major triterpenoids in the natural extract, by CG-EIMS and NIST Mass Spectrometry Data Center. The acetonic extract was chemically modified by reactions of acid hydrolysis, sulfonylation, acetylation, methylation and silylation. The in-vitro antibacterial activity was evaluated against Gram-positive and Gram-negative bacteria. The acetonic extract showed significant activity only against Gram-positive bacteria (MIC\/MBC = 2\/9 mg\/mL). The hydrolyzed extract improve the bioactivity to both, Gram-positive and Gram-negative (MIC\/MBC = 2\/8 mg\/mL). Selectively, the acetylated extract was only effective toward Staphylococcus (MIC\/MBC = 7\/7 mg\/mL). The tosylated extract was active against Gram-positive and P. aeruginosa (MIC\/MBC = 24\/24 mg\/mL) and the silylated against Gram-positive and E. coli. (MIC\/MBC = 15\/15 mg\/mL). The antioxidant activity was determining by DPPH and ABTS assays. Hydrolyzed extract increased the antioxidant properties (DPPH, IC50,(mg\/mL) = 0.077 ± 0.007; ABTS IC50,(mg\/mL) = 0.032 ± 0.005). The acylated and alkylated extracts reduce the bioactivity and silylated derivative eliminated the bioactivity. These results could be considered as a possible strategy to obtain antimicrobial agents from herbal medicines.Keywords: Zinnia peruviana, modified extracts, phytosterols, antibacterial activity, antioxidant properties","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242307,"idioma_id":5,"titulo":"Implantes PEEK de última generación. Estudio al MEB","resumen":"El PEEK, poli-éter-éter-cetona, es un termoplástico de doble fase que desde los años 90 se ha abierto paso entre los biomateriales como reemplazo de implantes con componentes metálicos, principalmente para implantes de columna vertebral y ortopédicos. luego de mushos estudios se han encontrado que este material tiene gran cantidad de propiedades físicas, mecánicas y de superficie que lo convierten en un material apto para implantes dentales. Se destacan las propiedades estéticas, la rugosidad, la porosidad, flexibilidad y resistencia a la compresión entre otras cualidades.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242309,"idioma_id":4,"titulo":"Glutamine protection in an experimental model of acetaminophen nephrotoxicity","resumen":"Acetaminophen (APAP) is a widely prescribed analgesic and antipyretic drug. In the present work, we studied the effects of glutamine (Gln) in an in vivo model of APAP-induced nephrotoxicity in male Wistar rats. Renal function, histological characteristics, and Na+,K+-ATPase cortical abundance and distribution were analyzed. The appearance of HSP70 and actin in urine was also evaluated. Myeloperoxidase (MPO) activity in cortical tissue was measured as an index of the inflammatory response. Gln administration 30 min before APAP protected from the renal functional and histological damage promoted by APAP. Rats that received the dual treatment Gln and APAP (Gln\/APAP) showed the same level of Na+,K+-ATPase cortical induction as APAP-treated animals, but the enzyme maintained its normal basolateral localization. HSP70 abundance was increased up to the same level in the Gln, APAP, and Gln\/APAP groups. Urinary HSP70 and actin were detected only in the APAP-treated animals, reinforcing the protection of renal tubular integrity afforded by the Gln pretreatment. Gln pretreatment also protected from the increment in MPO activity promoted by APAP. Our results support the idea that Gln pretreatment could be a therapeutic option to prevent APAP-induced renal injury.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242311,"idioma_id":4,"titulo":"Impact toughness transition temperature of ferritic Fe-Al-V alloy with strengthening Fe2AlV precipitates","resumen":"The Fe2AlV-strengthened ferritic alloys show an appreciable flow stress and creep strength up to 700 ºC, comparable to those of other iron aluminide based alloys with coherent microstructures. In the present study, the brittle-to-ductile transition temperature (BDTT) of the Fe76Al12V12 alloy was investigated in the peak hardness condition by Charpy test. A BDTT value of 617 °C was estimated using the criterion of the midpoint of the impact-energy transition region. An attempt is made to gain understanding of the micro-mechanisms controlling the fracture process and their interaction with the microstructure in order to identify ways for enhancing ductility in disordered Fe-Al alloys strengthened by coherent precipitates.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242312,"idioma_id":4,"titulo":"Sexual differences in the effect of previous breeding performance on nest-box reuse and mate retention in White-rumped Swallows (Tachycineta leucorrhoa)","resumen":"In birds, the selection of nesting sites and mates has a profound influence on the daily interactions of individuals. Both behaviours are energetically costly and time-consuming and can strongly affect the Darwinian fitness of individuals. Using a 12-year dataset on banded returning breeders, we explored variables associated with nest-box choice and mate choice in the White-rumped Swallow, a socially monogamous migratory passerine. Females reusing nest-boxes, but not males, produced significantly more fledglings than did those that changed nest-boxes. Females and males that retained mates produced significantly more fledglings than did those that divorced. General linear mixed models revealed that the number of fledglings produced in previous seasons significantly explained the reuse of particular nest-boxes by females, but not by males. Mate choice by females was not strongly affected by either past breeding performance or nest-box reuse, but nest-box reuse alone predicted mate choice by males. Nest-box reuse by males was apparently more related to retention of female partners. This study revealed that sexual differences in the nesting and mating decisions were guided by the use of information on past breeding performance in a subtropical, secondary cavity nester.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242313,"idioma_id":4,"titulo":"Use of noninvasive &lsquo;bug-eggs&rsquo; to enable comparative inferences on genetic mating system with and without parental information: A study in a cattle egret colony","resumen":"Colonial waterbirds such as herons, egrets and spoonbills exhibit ecological characteristics that could have promoted the evolution of conspecific brood parasitism and extra-pair copulation. However, an adequate characterization of the genetic mating systems of this avian group has been hindered by the lack of samples of elusive candidate parents which precluded conducting conventional parentage allocation tests. Here, we investigate the genetic mating system of the invasive cattle egret using hematophagous insects contained in fake eggs to collect blood from incubating adults in a wild breeding colony. We tested a protocol with a previously unused Neotropical Triatominae, Panstrongylus megistus, obtained blood samples from males and females in 31 nests built on trees, drew blood from 89 nestlings at those nests, and genotyped all samples at 14 microsatellite loci, including six new species-specific loci. We comparatively addressed the performance of parentage allocation versus kinship classification of nestlings to infer the genetic mating system of cattle egrets. In line with previous behavioral observations, we found evidence in support of a non-monogamous genetic mating system, including extra-pair paternity (EPP) and conspecific brood parasitism (CBP). Parentage allocation tests detected a higher percentage of nests with alternative reproductive tactics (EPP: 61.7%; CBP: 64.5%) than the kinship classification method (EPP: 50.0%; CBP: 43.3%). Overall, these results indicate that rates of alternative reproductive tactics inferred in the absence of parental genetic information could be underestimated and should be interpreted with caution. This study highlights the importance of incorporating samples from candidate parents to adequately determine the genetic mating system of a species. We expand knowledge on the reproductive tactics of colonial waterbirds, contributing novel data on the genetic mating system of the cattle egret, valuable for the design of management strategies for this invasive bird.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242314,"idioma_id":4,"titulo":"Genetic differentiation and historical demography of wood stork populations in Brazilian wetlands: Implications for the conservation of the species and associated ecosystems","resumen":"Wetlands areincreasingly threatened by anthropogenic actions worldwide. Genetic monitoring ofassociated wildlife provides valuable data to support theirconservation. Waterbirds such asthe wood stork (Mycteria americana) are good bioindicators of wetlandsdisturbances and destruction. This studyinvestigates past and contemporary levels of genetic diversity, differentiation anddemographic processes in 236 wood storks from two major wetlands in Brazil in whichbreeding colonies are concentrated, using nine microsatellite lociand a 237-bp untranslatedfragment of the mitochondrial Control Region. Amapá populations(northern region) showed slightly higher levels of genetic diversity than Pantanalpopulations (central western region) and both populations had a lownumber of effectivebreeders.Results fromassignment tests, F-statistics, AMOVA, spatial and non-spatialBayesianclustering analysessupport the hypothesis of ongoing gene flow among colonies within regions, butsignificant differentiation between regions.The better supportedBayesian coalescent models based on both markers indicated that the northernpopulation exchanged migrants with unsampled populations, and thatthe central westernpopulation was founded by individuals from the north. Mitochondrial estimates revealedthat the timing of population divergence broadly overlapped the Last Glacial Maximum(LGM), and that the central western population expanded more recently than the northernpopulation. The results supportthe hypothesis that the coastal wetlands in northern Brazil remained stableenough to shelter large wood stork populations during the LGM andstorks colonized freshwaterwetlands in the central western region following deglacial warming. Conservationpolicies and protective measures should consider Amapá and Pantanal wood storkpopulations as genetically differentiated units and priority shouldbe given to Amapá populationswhich represent the source gene pool. Continuous genetic monitoring of wood storkscould help detect genetic signs of changes in demographic trends thatcould reflect alterationsor degradation in wetlands.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242315,"idioma_id":4,"titulo":"Genetic structure in the southernmost populations of black-and-gold howler monkeys (Alouatta caraya) and its conservation implications","resumen":"Black-and-gold howler monkeys Alouatta caraya, are arboreal primates, inhabitants of Neotropical forests, highly susceptible to the yellow fever virus, considered early?sentinels? of outbreaks, and thus, of major epidemiological importance. Currently, anthropogenic habitat loss and modifications threatens their survival. Habitat modification can prevent, reduce or change dispersal behavior, which, in turn, may influence patterns of gene flow. We explored past and contemporary levels of genetic diversity, elucidated genetic structure and identified its possible drivers, in ten populations (n = 138) located in the southernmost distribution range of the species in South America, in Argentina and Paraguay. Overall, genetic variability was moderate (ten microsatellites: 3.16 ± 0.18 alleles per locus, allelic richness of 2.93 ± 0.81, 0.443±0.025 unbiased expected heterozygosity; 22 haplotypes of 491-bp mitochondrial Control Region, haplotypic diversity of 0.930 ± 0.11, and nucleotide diversity of0.01± 0.007). Significant evidence of inbreeding was found in a population that was, later, decimated by yellow fever. Population-based gene flow measures (FST = 0.13; &#952;ST = 018), hierarchical analysis of molecular variance and Bayesian clustering methods revealed significant genetic structure, grouping individuals into four clusters. Shared haplotypes and lack of mitochondrial differentiation (non-significant &#952;ST) among some populations seem to support the hypothesis of historical dispersal via riparian forests. Current resistance analyses revealed a significant role of landscape features in modeling contemporary gene flow: continuous forest and riparian forests could promote genetic exchange, whereas disturbed forests or crop\/grassland fields may restrict it. Estimates of effective population size allow anticipating that the studied populations will lose 75% of heterozygosity in less than 50 generations. Our findings suggest that anthropogenic modifications on native forests, increasingly ongoing in Northeastern Argentina, Southern Paraguay and Southeastern Brazil, might prevent the dispersal of howlers, leading to population isolation. To ensure long-term viability and maintain genetic connectivity of A. caraya remnant populations, we recommend preserving and restoring habitat continuity. To conserve the species genetic pool, as well, the four genetic clusters identified here should be considered separate Management Units and given high conservation priority. In light of our findings and considering complementary non-genetic information, we suggest upgrading the international conservation status of A. caraya to ?Vulnerable?.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242316,"idioma_id":4,"titulo":"Toxoplasma gondii serine-protease inhibitor-1: a new adjuvant candidate for asthma therapy","resumen":"Serine-proteases are important players in the pathogenesis of asthma, promoting inflammation and tissue remodeling. It?s also known that many serine protease inhibitors display immunomodulatory properties. TgPI-1 is a Toxoplasma gondii protein that exhibits broad spectrum inhibitory activity against serine proteases. In view of the increased prevalence of atopic disorders and the need to develop new treatment strategies we sought to investigate the potential of TgPI-1 for treating respiratory allergies. For this purpose, we developed a therapeutic experimental model. BALB\/c mice were rendered allergic by intraperitoneal ovalbumin-alum sensitization and airway-challenged. Once the asthmatic phenotype was achieved, mice were intranasally treated with rTgPI-1 alone or with a mixture of rTgPI-1 and ovalbumin (OVA). A week later mice were given a secondary aerosol challenge. Treatment with rTgPI-1 alone or co-administered with OVA diminished bronchoalveolar eosinophilia, mucus production and peribronchial lung infiltration. This effect was accompanied by a lung resistance reduction of 26.3% and 50.3% respectively. Both treatments resulted in the production of lower levels of IL-4, IL-5, IFN-&#947; and regulatory IL-10 by thoracic lymph node cells stimulated with OVA. Interestingly, significant decreases in OVA specific IgE and T cell proliferation, and increases in FoxP3+ T cells at local and systemic levels were only detected when the inhibitor was administered along with OVA. These results show that both rTgPI-1 treatments reduced asthma hallmarks. However, co-administration of the inhibitor with the allergen was more effective. Hence, rTgPI-1 emerges as a novel adjuvant candidate for asthma treatment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242317,"idioma_id":4,"titulo":"Toxoplasma gondii serine-protease inhibitor-1: a new adjuvant candidate for asthma therapy","resumen":"Serine-proteases are important players in the pathogenesis of asthma, promoting inflammation and tissue remodeling. It?s also known that many serine protease inhibitors display immunomodulatory properties. TgPI-1 is a Toxoplasma gondii protein that exhibits broad spectrum inhibitory activity against serine proteases. In view of the increased prevalence of atopic disorders and the need to develop new treatment strategies we sought to investigate the potential of TgPI-1 for treating respiratory allergies. For this purpose, we developed a therapeutic experimental model. BALB\/c mice were rendered allergic by intraperitoneal ovalbumin-alum sensitization and airway-challenged. Once the asthmatic phenotype was achieved, mice were intranasally treated with rTgPI-1 alone or with a mixture of rTgPI-1 and ovalbumin (OVA). A week later mice were given a secondary aerosol challenge. Treatment with rTgPI-1 alone or co-administered with OVA diminished bronchoalveolar eosinophilia, mucus production and peribronchial lung infiltration. This effect was accompanied by a lung resistance reduction of 26.3% and 50.3% respectively. Both treatments resulted in the production of lower levels of IL-4, IL-5, IFN-&#947; and regulatory IL-10 by thoracic lymph node cells stimulated with OVA. Interestingly, significant decreases in OVA specific IgE and T cell proliferation, and increases in FoxP3+ T cells at local and systemic levels were only detected when the inhibitor was administered along with OVA. These results show that both rTgPI-1 treatments reduced asthma hallmarks. However, co-administration of the inhibitor with the allergen was more effective. Hence, rTgPI-1 emerges as a novel adjuvant candidate for asthma treatment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242318,"idioma_id":4,"titulo":"New records of bats (Mammalia: Chiroptera) for a southern locality of the Argentine Yungas","resumen":"The forests of northwestern Argentina representone of the most diverse areas of the country, but also oneof the most affected by human activities. The southernborder of this region is a transition area with the Dry ChacoEcoregion and represents a poorly studied zone. The aim ofthis study was to assess the diversity of bats at the villageof Escaba, southern Tucuman. Seven field surveys wereconducted at five different sites. A total of 120 specimensin three families and 14 species were recorded, 12 of themrepresenting new records for the study area, increasingthe species richness of Escaba from four to 16 species. Thearea will be recommended as an AICOM, a status given bythe RELCOM, thereby promoting actions to preserve thespecies of bat in the area.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242320,"idioma_id":4,"titulo":"Ulnar articular surface 3-D landmarks and ecomorphology of small mammals: A case of study in two Early Miocene typotheres (Notoungulata) from Patagonia","resumen":"Articular surfaces reflect the relative movements betweenadjacent bones, and the ones involved in the elbow joint provide informationabout forelimb movements and may be useful for making inferences about thesubstrate use. The proximal articular surface of the ulna was examined through3-D geometric morphometrics, in order to assess its usefulness as a proxy forpaleoecological interpretations; particularly for two small mammals from theEarly Miocene of Patagonia. The sample was composed of 22 extant small mammals(rodents, carnivorans and primates) and two extinct typotheres: Hegetotherium mirabile (Hegetotheriidae) and Interatheriumrobustum (Interatheriidae).Forty-five landmarks were taken and principal component analysis (PCA) was usedto explore the morphospace structure. The results of PCA for the whole surface wereinconclusive; therefore, successive analyses were made, subdividing the surfaceinto sub-units. The PCA for the proximal part of the trochlear notch was themost informative, allowing the recognition of morphospaces with functionalvalue: one for digging rodents and another for most climbers. Neither typotherewould have had a specialisation for climbing or digging in the featuresanalysed. This study allows morphological patterns on different parts of ajoint to be detected; interpreted, at least partially, as differentialresponses to different kinds of mechanical stress.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242321,"idioma_id":4,"titulo":"Teeth complexity, hypsodonty and body mass in Santacrucian (Early Miocene) notoungulates (Mammalia)","resumen":"Notoungulates, native South American fossil mammals, havebeen recently objective of several palaeoecological studies. Ecomorphology andbiomechanics of the masticatory apparatus, together with micro and mesowearanalyses on tooth enamel, were applied in order to understand their palaeobiology.In particular, the relationship between some dental traits (hypsodonty,occlusal surface area and complexity) and body mass is still poorly understood.These features were measured by means of the hypsodonty index (HI), occlusalsurface area (OSA) and tooth area (OTA), enamel crest complexity (ECC) andlength (OEL). The relationships between these indices were evaluated in fivepan-contemporaneous Santacrucian Notoungulata genera from Patagonia: Adinotherium and Nesodon (Toxodontia), Interatherium,Protypotherium and Hegetotherium (Typotheria). While OSA, OTAand OEL were size dependent and strongly correlated, HI and ECC were size independent.All notoungulates analysed have very hypsodont teeth, indicating high rates oftooth wear in response to an increase of abrasives consumed with the food;their tooth occlusal area and complexity could be related to chewing effortsassociated with the toughness of the plants consumed. HI, OSA and ECC wereconsidered useful for palaeoecological reconstructions, but the resultspresented here show that these three features are integrated as a complex, soshould not be evaluated separately.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242322,"idioma_id":4,"titulo":"Three-dimensional cranial ontogeny in pantherines (Panthera leo, P. onca, P. pardus, P. tigris; Carnivora: Felidae)","resumen":"The Panthera lineage is a monophyletic clade of felids,supported by both morphological and molecular evidence. The lineage includeslarge species with cranial similarity such as Panthera leo and P. tigris, and other with very differentcranium such as P. pardus. The aim ofour work was to study the cranial ontogeny of Pantherines, elucidating whethertheir cranial shape is a product of size or phylogeny, and to compare thesefindings with available information about other carnivores. We studied 370specimens using geometric morphometrics technique in three dimensions. Panthera leo and P. tigris showsimilar ontogenetic trajectories, sharing adult crania with wider rostrum,shorter basicranium and vertical occipital plate. The cranial configuration of P. leois a scaling version of P. tigris. P. pardus shows the mostdifferent cranial pattern, with adults having a rounded braincase and zygomaticarches less expanded than the rest, whereas P.onca occupies an intermediate place betweenthese patterns. P. pardus is the species with the smallestbirth weight and the lowest growth rate, reaching a final size and shape laterthan the remaining species. Adult shape morphology reflects no relation to phylogeneticplacement of the species and it is probably related to Pantherine body size.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242323,"idioma_id":4,"titulo":"Prevalence and intensity of fleas parasitizing an isolated population of screaming hairy armadillo in Buenos Aires province, Argentina: host-related factors and temporal dynamics","resumen":"Fleas (Siphonaptera) of an isolated population ofChaetophractus vellerosus (Mammalia: Xenarthra) fromMagdalena (Buenos Aires province) were studied, and theirpresence was associated with host-related factors (age, sex,weight, size, and physical condition) and temporal dynamics(seasonality and year). Three species of fleas were identified:Polygenis (Polygenis) platensis (Rhopalopsyllidae), Tungapenetrans (Tungidae), and Pulex irritans (Pulicidae).Prevalences were significant for year, season, and physicalcondition. Intensities were significantly different for year,physical condition, and weight. The intensities of fleas werehigher in 2009 than in other years, probably because of lowerrainfall than the annual average leading to extremely dry climaticconditions in 2008. Intensities decreased in individualswith major body weight and increased in individuals withpoor physical condition. In this study, the dynamics of the fleacommunity associated with an armadillo population is analyzedfor the first time taking into account host-related factorsand temporal dynamics, and also how these factors influencethe community.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242324,"idioma_id":4,"titulo":"Large and Small Magellanic Clouds age-metallicity relationships","resumen":"Abstract \/ We present a new determination of the age-metallicity relation for both Magellanic Clouds, estimatedthrough the homogeneous analysis of 239 observed star clusters. All clusters in our set were observed with theCT1 filters of the Washington photometric system. The Automated Stellar cluster Analysis package (ASteCA)was employed to derive the cluster?s fundamental parameters, in particular their ages and metallicities, throughan unassisted process. We find that our age-metallicity relations (AMRs) can not be fully matched to any ofthe estimations found in twelve previous works, and are better explained by a combination of several of them indifferent age intervals.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242326,"idioma_id":4,"titulo":"Recluse spiders produce flattened silk rapidly using a highly modified, self-sufficient spinning apparatus","resumen":"Arthropod silk is among the most remarkable materials produced by animals, and is diverse in chemical composition and strand morphology. Different types of silk are produced by different spinning processes, and spiders show the greatest diversity in both. Extremely flattened silk strands with exceptional properties are spun by recluse spiders (Loxosceles spp.) using a single pair of spigots, but this spinning process remains unknown. We here combine movies, electron microscopy, and X-ray microscopy to investigate how Loxosceles laeta spin their peculiar silk. We found that L. laeta show a unique weaving behaviour: the two anterior lateral spinnerets move very rapidly (8.5?13 times per second), each spinning a single strand of silk that is held by the posterior spinnerets; the silk is never pulled with the legs. Outgroup comparison with closely related spider families reveals that recluse spiders have a highly modified spinneret morphology, with elongate anterior spinnerets, a diastema between the spinnerets, modified setae that possibly help holding the silk strands, and long and thin muscles associated to the spinnerets. In contrast to all other arthropods, these morphological specializations allow them to rapidly spin without using the legs or the substrate ? revealing the first self-sufficient spinning apparatus in arthropods. This explains how a dense, sticky silk can be constructed from a single pair of spigots in a fast manner.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242327,"idioma_id":5,"titulo":"Estimación de la diversidad de arañas de la familia Theridiidae (Araneae) en la Reserva Natural e Histórica Isla Martín García (Buenos Aires-Argentina)","resumen":"Las arañas son consideradas de importancia para estudios de biodiversidad, conservacióny sucesión. Presentan facilidad para dispersarse y establecerse en nuevos hábitats por loque son buenos colonizadores de territorios insulares. La familia de arañas Theridiidaees una de las más diversas, representada por una gran variedad morfológica, etológica yecológica. En Argentina no existen trabajos referidos a terídios de territorios insulares,por lo tanto, este trabajo consiste en el primer registro de la familia en estos ambientes.La Isla Martín García es una Reserva Natural e Histórica que se ubica en el sector norestedel Río de La Plata y presenta variabilidad ambiental y florística. Para analizar la riquezaespecífica, abundancia relativa y diversidad alfa y beta de terídios se realizaron muestreosdurante tres años consecutivos mediante red de golpeo y muestreo manual. Se capturaronun total de 1173 individuos, pertenecientes a nueve géneros y 21 morfoespecies. Laespecie más abundante en todos los ambientes fue Cryptachaea hirta (61,68%). Laselva fue el ambiente con mayor diversidad (H? = 1,9, J = 0,67) (S = 16), brindandouna vasta vegetación, con amplios recursos para la subsistencia de estas arañas. La islano correspondería a un área de importancia respecto a la singularidad de especies. Seencontraron tres nuevos registros para Argentina: C. altiventer, Theridion positivum y T.tinctorium.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242328,"idioma_id":4,"titulo":"Homalodotheriidae and Homalodotherium: comments on an old nomenclatural conflict","resumen":"This note tries to clarify some mistakes concerning the spelling and authorship of the genus Homalodotherium and the family Homalodotheriidae. The confusion comes from the original full description by Flower, where the author changed the original spelling Homalodotherium by Homalodontotherium. At the same time, Flower presented a short abstract where he maintained the name Homalodotherium. The earlier publication of the abstract validates the latter name, though Homalodontotherium was used during decades. The family Homalodontotheridae was created by Ameghino; years later, Gregory corrected the spelling to Homalodotheriidae, but this is an automatic correction that does not justify the taxon authoring change.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242329,"idioma_id":4,"titulo":"A revision of the wolf spider genus Diapontia Keyserling, and the relationships of the subfamily Sosippinae (Araneae: Lycosidae)","resumen":"The South American genus Diapontia is revised to include nine species: Diapontia uruguayensis Keyserling, 1877 (= Diapontia senescens Mello-Leitão, 1944 syn.n.; D. infausta Mello-Leitão, 1941 syn.n.; D. pourtaleensis Mello-Leitão, 1944 syn.n.; D. albopunctata Mello-Leitão, 1941 syn.n.) from northern Paraguay, southern Uruguay, north-central Argentina and southern Chile; D. niveovittata Mello-Leitão, 1945 from southern Paraguay, north-central Argentina and southern Brazil; D. anfibia (Zapfe-Mann, 1979) comb.n. (= Lycosa artigasi Casanueva, 1980) from central and southern Chile and southwestern Argentina, transferred from Pardosa C. L. Koch, 1847; D. securifera (Tullgren, 1905) comb.n. from northern Chile and northwestern Argentina, transferred from Orinocosa Chamberlin, 1916; D. arapensis (Strand, 1908) comb.n., from Peru, transferred from Hippasella Mello-Leitão, 1944; D. calama sp.n. from northern Chile; D. songotal sp.n. from southern Bolivia; D. chamberlini sp.n. from central and southern Peru; and D. oxapampa sp.n. from northern Peru. The sister-group relationship between Diapontia and Hippasella, and their placement in the subfamily Sosippinae, were supported by phylogenetic analyses based on four molecular markers (28S, 12S, NADH1 and COI), using Bayesian inference and maximum-likelihood. We tested whether DNA barcoding techniques were able to corroborate the identity of four Diapontia species. Diapontia securifera and D.anfibia were successfully identified using COI; however, D. niveovittata and D. uruguayensis were found to share identical haplotypes and thus could not be discriminated.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242334,"idioma_id":4,"titulo":"Stability of the Duality Gap in Linear Optimization","resumen":"In this paper we consider the duality gap function g that measures the difference between the optimal values of the primal problem and of the dual problem in linear programming and in linear semi-infinite programming. We analyze its behavior when the data defining these problems may be perturbed, considering seven different scenarios. In particular we find some stability results by proving that, under mild conditions, either the duality gap of the perturbed problems is zero or+&#8734;around the given data, or g has an infinite jump at it. We also give conditions guaranteeing that those data providing a finite duality gap arelimits of sequences of data providing zero duality gap for sufficiently small perturbations, which is a generic result.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242335,"idioma_id":4,"titulo":"Teeth complexity, hypsodonty and body mass in Santacrucian (Early Miocene) notoungulates (Mammalia)","resumen":"Notoungulates, native South American fossil mammals, have been recently objective of several palaeoecological studies. Ecomorphology and biomechanics of the masticatory apparatus, and micro and mesowear analyses on tooth enamel were applied in order to understand their palaeobiology. In particular, the relationship between some dental traits (hypsodonty, occlusal surface area and complexity) and body mass is still poorly understood. These features were measured by means of the hypsodonty index (HI), occlusal surface area (OSA) and tooth area (OTA), enamel crest complexity (ECC) and length (OEL). The relationships between these indices were evaluated in five pan-contemporaneousSantacrucianNotoungulata genera from Patagonia: Adinotherium and Nesodon (Toxodontia), Interatherium,Protypotherium and Hegetotherium (Typotheria). While OSA, OTA and OEL were size dependent and strongly correlated, HI and ECC were size independent. All notoungulates analysed have very hypsodont teeth indicating high rates of tooth wear in response to an increase of abrasives consumed with the food; their tooth occlusal area and complexity could be related to chewing efforts associated with the toughness of the plants consumed. HI, OSA and ECC were considered useful for palaeoecological reconstructions, but the results presented here show that these three features are integrated as a complex, so they should not be evaluated separately","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242336,"idioma_id":4,"titulo":"In Vivo Paracoccidioides sp. Biofilm on Vascular Prosthesis","resumen":"Paracoccidioidomycosis is an endemic mycosis caused by Paracoccidioides species limited to Latin America arising with the chronic form in 90% of cases. The capacity of microorganisms to form biofilms is considered of great importance medical since can contribute to the persistence and to the chronic state of the diseases. The ability of Paracoccidioides to form biofilm has been demonstrated in vitro. In our study, for the first time we have observed this capability in vivo on a vascular prosthesis using scanning electron microscope showing a dense network of Paracoccidioides yeasts covered by an extracellular matrix.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242338,"idioma_id":5,"titulo":"Proyecto para la Urbanización del Presio ferroviario de la Estación Mendoza","resumen":"CONCURSO NACIONAL DE MASTER PLAN E IDEAS MORFOLÓGICAS. DISTRITO SUSTENTABLE: ESTACIÓN MENDOZA.El objetivo es elaborar un modelo sustentable, económico, social, y de recuperación patrimonial, que tienda al desarrollo e integración de un predio ferroviario con la ciudad de forma inclusiva y sustentable.Las antiguas construcciones industriales casi sin uso, representan hoy uno de los espacios más significativos de intervención en la ciudad de Mendoza. Por su ubicación estratégica dentro del tejido urbano capitalino y reconocido como núcleo central de un área Metropolitana de aproximadamente un millón de habitantes, se manifiesta la importancia de llevar adelante la formulación de un proyecto integral de desarrollo del sector a fin de recomponer la fisura histórica de la trama urbana y consiguiente malla social.El objetivo de este Concurso Nacional de Ideas es realizar un Master Plan en el Predio del Ferrocarril para que la Ciudad capital de la Provincia de Mendoza pueda crecer de forma sustentable con recuperación Patrimonial logrando el desarrollo e integración del Predio a la ciudad. El Distrito Sustentable será para la ciudad de Mendoza, un lugar desde donde poder implementar políticas sustentables, desde el urbanismo, la arquitectura, la ingeniería, las ciencias políticas y sociales, que en forma multidisciplinar, logren la concreción de una nueva visión urbana. El jurado otorgó el primer premio a los autores arquitectos Guillermo Lesch y Santiago Belozercovsky, en conjunto con los colaboradores arquitectos Patricio Dato, Paula Lesch y Pablo Calocero, quienes expresan la necesidad de ?recomponer la fisura histórica a través de la necesaria incorporación de las practicas sustentables que reclama el actual momento histórico?. El conjunto edilicio de la propuesta ganadora escalona hacia el espacio liberado, hacia el parque y hacia la cordillera; elemento emblemático del entorno. Esta presencia cordillerana es insoslayable, y hacer referencia a ella es fundamental para recrear la identidad y memoria popular del sitio. Entre la elevación natural y la elevación edilicia se conforma el valle. En este valle se recrea la identidad de Mendoza, se pone en relieve su tradición sustentable, poniendo en valor su riego por acequias, su iniciativa de transporte sostenible, el verde, sus valles y viñedos; su memoria edilicia y ferroviaria, de manera tal que cualquier visitante de la ciudad que viste el distrito sustentable podrá rápidamente reconocer la identidad de la zona.El Proyecto busca la integración y la conectividad con el resto de la ciudad a través del espacio público, sucesión de plazas y recorridos peatonales. Se plantea una serie de atractores urbanos que, vinculados unos con otros, buscan darle identidad al conjunto, dinamizar las relaciones, crear nuevas centralidades y generar conciencia ambiental de toda la comunidad: paseos peatonales, bicisendas, espejos de agua y zonas de estar, huertas urbanas, mercado orgánico, ferias artesanales, ferias gastronómicas, museo de la sustentabilidad, museo ferroviario al aire libre, terrazas gastronómicas, skatepark, y talleres de reciclados y oficios. S propone la puesta en valor de la traza del metrotranvia, dotándolo de entorno de solados y equipamiento urbano producido por la integración de la vereda peatonal este de la avenida Belgrano a la traza del metrotranvia. Como primer paso se propone mantener el eje Avenida Belgrano y densificar a ambos lados de la traza, recomponiendo la cuadricula y tendiendo a compactar tejido, liberando el resto del espacio para parque público. La propuesta ganadora planea mixturar este sector construido con el parque público, recomponiendo la fisura histórica a través de la necesaria incorporación de prácticas sustentables, ampliando los espacios verdes y la forestación, incorporando usos mixtos: residencial, comercial y cultural; centros de ferias regionales, distrito de diseño, arte y música, recreativo y nuevas tipologías de viviendas.Se propone peatonalizar el conjunto manteniendo como vehiculares sólo la calle Godoy Cruz y la avenida Belgrano a fin de no perder conectividad Norte-Sur. Las peatonales transversales recorren el conjunto edilicio y rematan en el parque publico. Se plantea causar el menor impacto posible sobre el medio ambiente y el territorio, consumir la menor cantidad de recursos y energía y generar la menor cantidad posible de residuos y emisiones.Las acciones propuestas en este Concurso persiguen claros objetivos de intervención urbana, ambiental y patrimonial.La incorporación de esta nueva pieza urbana no sólo tendrá implicancias en sus bordes, sino que será un elemento de atracción y desarrollo a nivel metropolitano, excediendo el ámbito barrial y contribuyendo a dinamizar la economía local, mejorando la calidad de vida de sus ciudadanos.El Distrito Sustentable significará para la ciudad de Mendoza el punto de apoyo desde donde manifestar el espíritu de una ciudad pujante; donde implementar políticas sustentables desde el Urbanismo, la Arquitectura, la Ingeniería y las Ciencias Políticas y Sociales en forma multidisciplinar para que logren la concreción de una nueva visión urbana con usos mixtos y espacios verdes en armonía con su patrimonio arquitectónico, natural y social.Mendoza es una ciudad con un importante patrimonio tangible, cultural y natural. Así como también, un patrimonio cultural intangible que debe ser considerado con espíritu innovador. Es de vital importancia para la Municipalidad de la Ciudad de Mendoza la preservación y puesta en valor del patrimonio del sector a intervenir. La  incorporación del Predio de la Estación Mendoza del Ferrocarril a la ciudad, de forma gradual y armónicamente, pretende se convierta en un espacio de calidad ambiental.Se busca preservar, recuperar y refuncionalizar áreas y edificios patrimoniales, vías ferroviarias existentes, reconociendo las viejas trazas, la estructura vial y edilicia ferroviaria, como así también el patrimonio cultural de Mendoza, el árbol y el agua.El Proyecto ganador tiene como objetivo generar un entorno urbano que no atente contra el medio ambiente, y que proporcione recursos urbanísticos suficientes para garantizar que el sitio a intervenir se transforme en un lugar que ofrezca mejor calidad de vida a sus habitantes, respondiendo a las demandas sociales de su entorno y asegurando la participación ciudadana.Considerando los cambios producidos en el modelo de desarrollo local y en su composición social, resulta necesario producir cambios morfológicos y funcionales en el área que permitan asignarle un carácter identitario que lo vincule a la ciudad actual y al modelo de ciudad deseado.FICHA TÉCNICAConcurso Nacional Master Plan e Ideas Morfológicas. Distrito Sustentable. Estación Mendoza Organizadores del Concurso: Municipalidad de Mendoza ? Federación Argentina de Entidades de Arquitectos (FADEA) ? Colegio de Arquitectos de Mendoza (CAMZA)Año: 2017Autores ganadores: Arq. Guillermo Lesch - Santiago Belozercovsky. Colaboradores: Arq. Patricio Dato - Paula Lesch - Pablo Calocero.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242339,"idioma_id":4,"titulo":"A survey on tomato leaf grey spot in the two main production areas of Argentina led to the isolation of Stemphylium lycopersici representatives which were genetically diverse and differed in&nbsp;their virulence","resumen":"Tomato gray leaf spot was first reported inArgentina in 1990. Since then, the disease has not onlyincreased in endemic areas, but also disseminated inother tomato-growing areas. In a survey of plants withtypical symptoms of Tomato grey leaf spot disease weisolated 27 Stemphylium representatives from the twomain tomato-growing areas of Argentina. Cultural featuressuch as sporulation, conidia morphometry amongothers revealed high variability between isolates, whichwas confirmed by Inter Simple Sequence Repeat(ISSR)-PCR technique. A molecular phylogenetic analysiscomprising the Internal Transcribed Spacer (ITS)and the glyceraldehyde-3-phosphate dehydrogenase(gpd) gene partial sequences unambiguously identifiedall isolates as Stemphylium lycopersici. Based on diseaseseverity on detached leaves, isolates were grouped inthree categories (high, medium and low virulent). Nocorrelation was found between phenotypic or genotypiccharacters and the geographical origin of the isolates.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242340,"idioma_id":4,"titulo":"The mitochondrial genome of the plant-pathogenic fungus Stemphylium lycopersici uncovers a dynamic structure due to repetitive and mobile elements","resumen":"Stemphylium lycopersici (Pleosporales) is a plant-pathogenic fungus that has been associated with a broad range of plant-hosts worldwide. It is one of the causative agents of gray leaf spot disease in tomato and pepper. The aim of this work was to characterize the mitochondrial genome of S. lycopersici CIDEFI-216, to use it to trace taxonomic relationships with other fungal taxa and to get insights into the evolutionary history of this phytopathogen. The complete mitochondrial genome was assembled into a circular double-stranded DNA molecule of 75,911 bp that harbors a set of 37 protein-coding genes, 2 rRNA genes (rns and rnl) and 28 tRNA genes, which are transcribed from both sense and antisense strands. Remarkably, its gene repertoire lacks both atp8 and atp9, contains a free-standing gene for the ribosomal protein S3 (rps3) and includes 13 genes with homing endonuclease domains that are mostly located within its 15 group I introns. Strikingly, subunits 1 and 2 of cytochrome oxidase are encoded by a single continuous open reading frame (ORF). A comparative mitogenomic analysis revealed the large extent of structural rearrangements among representatives of Pleosporales, showing the plasticity of their mitochondrial genomes. Finally, an exhaustive phylogenetic analysis of the subphylum Pezizomycotina based on mitochondrial data reconstructed their relationships in concordance with several studies based on nuclear data. This is the first report of a mitochondrial genome belonging to a representative of the family Pleosporaceae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242341,"idioma_id":5,"titulo":"Formas de abastecimiento de materias primas en el sistema textil artesanal y estrategias de reproducción social entre artesanas de la estepa patagónica","resumen":"Con foco en la producción textil artesanal en Patagonia, y desde una descripción etnográfica, se abordarán las vías de aprovisionamiento de materias primas (vellones de lana) para el hilado manual de la fibra, desde un grupo de artesanas, asociadas al Mercado de la Estepa, en la zona rural de la Provincia de Río Negro, Argentina.Pese a que el territorio patagónico se caracteriza por contar con una gran cantidad de ovinos, y ser Argentina una de las principales regiones laneras del mundo, la orientación del mercado de fibras hacia la exportación limita el acceso a insumos en la producción textil artesanal. En este contexto, quienes se dedican a esta tarea, como complemento de sus ingresos familiares, deben implementar diversas estrategias de reproducción, individuales y colectivas, mediadas y tensionadas por diversas reciprocidades, con el objeto de asegurarse el acceso a ciertos recursos. Específicamente, se analizarán las limitaciones alrededor de la conservación de ovinos criollos y del acceso a su fibra, tomando el caso de la oveja localmente denominada Linca.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242343,"idioma_id":4,"titulo":"Novel Preparation of Titania-Modified CMK-3 Nanostructured Material as Support for Ir Catalyst Applied in Hydrodenitrogenation of Indole","resumen":"Abstract: Iridium catalyst was prepared using a novel titanium oxide-CMK-3 support synthesized as a replica of Ti-SBA-15. The catalyst was applied in the hydrodenitrogenation of indole. The activity was compared with an iridium catalyst supported over a grafted titanium-CMK-3. Structural and textural characterization of the catalysts was performed by means of N2 adsorption, XRD, UV&ndash;Vis&ndash;DRS, Raman spectroscopy, XPS, TEM and H2 Chemisorption. Ir-Ti-CMK-3 was the most active catalyst for the hydrodenitrogenation reaction at mild conditions. Titanium oxide contained in carbon ordered mesoporous CMK-3 promotes a very good anchorage of iridium metallic clusters in the carbon framework reaching high active site distribution and more stable nanoclusters. Graphical Abstract: [Figure not available: see fulltext.]","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242344,"idioma_id":4,"titulo":"Nanostructured SBA-15 host applied in ketorolac tromethamine release system","resumen":"Abstract: The ordered mesoporous silica SBA-15 has been applied in studies of ketorolac tromethamine adsorption and release. The SBA-15 materials with hexagonal and regular structure were obtained using a triblock copolymer Pluronic P123 as a template and TEOS as a silica source. Ketorolac tromethamine was adsorbed into SBA-15 silica nanochannels using ethanol as solvent. The physicochemical and textural properties of SBA-15 and ketorolac tromethamine\/SBA-15 were characterized by X-ray diffraction, thermogravimetric analysis, transmission electron microscopy, fourier transform infrared spectroscopy and BET surface studies. Drug release was evaluated by soaking the loaded silica mesoporous material into a solution of HCl (0.1 N) at initial time (0&ndash;2 h) and buffer pH 7 at high times at 37 &deg;C under continuous stirring. Oral commercial Keto tablets (Dolten&reg;) and Keto solution (Keto power) were study for the contrast. Release studies were performed in order to evaluate the required therapeutic efficacy. SBA-15 provides significant improvement in the controlled release of ketorolac tromethamine. Graphical Abstract: Release profile of KETO from SBA-15\/KETO and control releases. [InlineMediaObject not available: see fulltext.].","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242345,"idioma_id":4,"titulo":"Novel preparation of CMK-3 nanostructured material modified with titania applied in hydrogen uptake and storage","resumen":"This work deals with the development of a novel procedure to synthesize titania-modified nanostructured carbon employing Ti-SBA-15 as hard template. The new mesoporous carbon displays high specific surface area of 1044 m2\/g and large pore volume of 0.7 cm3\/g. XRD pattern of Ti-CMK-3 indicates that the ordered structure of this material is similar to the CMK-3. XRD, XPS and UV-Vis-DRS analysis indicated that Ti is highly dispersed as anatase phase in Ti-CMK-3. The synthesized Ti-CMK-3 exhibited significantly enhanced H2 storage properties (2.6 wt%, equivalent to 13 mmol\/g) compared with CMK-3 without Ti (2.2 wt%, 11 mmol\/g) at 77 K and 10 bar.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242346,"idioma_id":4,"titulo":"Vanadium oxide supported on mesoporous SBA-15 modified with Al and Ga as a highly active catalyst in the ODS of DBT","resumen":"Vanadium oxides supported on mesoporous SBA-15 catalysts with different vanadium loadings were studied in the oxidative desulfurization (ODS) of dibenzothiophene as a model sulfur compound. The catalytic activity was improved when SBA-15 framework was modified by adding Al and Ga. Structural and textural characterization of the catalysts were performed by means of XRD, N2 adsorption, UV&ndash;Vis&ndash;DRS, XPS, NMR, TEM, Raman, TPR and Py-FTIR. UV&ndash;Vis&ndash;DRS and Raman demonstrated that highly dispersed vanadium VO4 &minus;3 species are responsible for the high activity in the sulfur removal. The Ga modified support with an intermediate V\/Si ratio of 1\/30 was the most active catalyst for ODS of DBT, using hydrogen peroxide as oxidant and acetonitrile as solvent. 100% of DBT elimination was attained at a short time in mild conditions. Gallium and aluminum incorporation into the support modified successfully the nature of the SBA-15 surface by generating Bronsted and Lewis acidity. The interaction between the acid sites with the active vanadium sites improved the activity of the catalysts. The high dispersion depended on the vanadium loading and on the nature of the support. The more acidic support allowed better dispersion of the vanadium species due to stronger interaction metal-support. The reusability of the catalysts indicates that vanadium oxide supported on mesoporous SBA-15 modified with Ga and Al are potential catalysts for the ODS of dibenzothiophene.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242348,"idioma_id":4,"titulo":"Synthesis, chemical and microstructural characterization of micro macroporous biphasic calcium phosphate granules","resumen":"n this paper a comparative study Argentine resorbable a new biomaterial, beta tricalcium phosphate (&#946;-TCP), formed from the reaction between calcium phosphates and glycolic acid with other existing on the market, marketed as performed Beta- TCP Odontit ®, American-made. This biomaterial is used as replacement of bone tissue in the maxillary sinus elevation, bone volume increased lateral or vertical defects, and periodontal defects filling or peri implant in humans.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242349,"idioma_id":4,"titulo":"Crystallographic texture and microstructural changes in fusion welds of recrystallized Zry-4 rolled plates","resumen":"This work presents a detailed characterization of the microstructural and crystallographic texture changes observed in the transition region in a weld between two Zircaloy-4 cold rolled and recrystallized plates. The microstructural study was performed by optical microscopy under polarized light and scanning electron microscopy (SEM). Texture changes were characterized at different lengthscales: in the micrometric size, orientation imaging maps (OIM) were constructed by electron backscatter diffraction (EBSD), in the millimetre scale, high energy XRD experiments were done at the Advanced Photon Source (USA) and compared to neutron diffraction texture determinations performed in the HIPPO instrument at Los Alamos National Laboratory. In the heat affected zone (HAZ) we observed the development of Widmanstätten microstructures, typical of the &#945;(hcp) to &#946;(bcc) phase transformation. Associated with these changes a rotation of the c-poles is found in the HAZ and fusion zone. While the base material shows the typical texture of a cold rolled plate, with their c-poles pointing 35° apart from the normal direction of the plate in the normal-transversal line, in the HAZ, c-poles align along the transversal direction of the plate and then re-orient along different directions, all of these changes occurring within a lengthscale in the order of mm. The evolution of texture in this narrow region was captured by both OIM and XRD, and is consistent with previous measurements done by Neutron Diffraction in the HIPPO diffractometer at Los Alamos National Laboratory, USA. The microstructural and texture changes along the HAZ were interpreted as arising due to the effect of differences in the cooling rate and &#946; grain size on the progress of the different &#945; variants during transformation. Fast cooling rates and large &#946; grains are associated to weak variant selection during the &#946;&#8722;>&#945; transformation, while slow cooling rates and fine &#946; grains result in strong variant selection.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242351,"idioma_id":4,"titulo":"Standardless semi-quantitative analysis by PIXE","resumen":"A method based on the refinement of atomic and experimental parameters developed for the description of PIXE spectra is presented and applied to standardless semiquantitative PIXE analysis. This method was implemented in the sofware PAMPA  (Parameter Assessment Method for PIXE Analysis) and consists in minimizing the quadratic differences between an experimental spectrum and an analytical function proposed to describe it. The first results of PAMPA are presented for the quantification of synthetic and mineral, thin and bulk samples, and they werecompared with results obtained with a commercial software.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242352,"idioma_id":4,"titulo":"Thickness determination of anodic titanium oxide films by electron probe microanalysis","resumen":"Thin film thickness can be readily associated to the x-ray intensities emitted under  electron bombardment. The aim of this work is to develop a method for measuring titanium oxide thicknesses in biomaterials from the x-ray spectra induced in a scanning electron microscope. The oxide layers studied were generated with different anodizing voltages applied in phosphoric and boric acid solution (H3PO4\/H3BO3). The oxygen K&#945; intensity was registered for each sample and related to the corresponding thickness. In order to account for local material alterations, a recalibration is shown to be necessary; Rutherford backscattering spectroscopy was used at this stage. The method is useful for TiO2 thicknesses in the range of interest for dental and orthopedic implants (10-100 nm), and it could be extended to greater thicknesses by adequately selecting the electron beam energy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242353,"idioma_id":4,"titulo":"Archaeological site formation processes in northwestern Patagonia, Mendoza Province, Argentina","resumen":"The Cañadón Amarillo area in northwestern Patagonia (Mendoza Province, Argentina) presents a rich archaeological record contained within thick successions of fine-grained deposits with well-constrained chronological and stratigraphic resolution. Geomorphological, sedimentological, and archaeological analysis of three archaeological localities, constrained by radiocarbon ages, was conducted to reconstruct site formation processes and depositional variability in an exposed, dryland setting. The archaeological sites are located in the Cañadón Amarillo area between the southern margin of the volcanic Payunia Plateau and the Colorado River, in an area of ephemeral streams and eolian sand sheets. The archaeological remains are preferentially contained in fine to very fine sand to silty sand deposits associated with the ephemeral streams. Low-energy fluvial deposition related to overbank flows, and eolian aggradation associated with coppice dunes, sand shadows, and unrippled and partially vegetated mantles have favored preservation of in situ archaeological materials. Our investigations provide insight into site formation processes in exposed settings within the semiarid parts of northwestern Patagonia and extend the local record of human occupation to &#8764;7300 14C yr B.P.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242354,"idioma_id":5,"titulo":"Explotaci&oacute;n de peces e intensificaci&oacute;n en ambientes &aacute;ridos: comparando el registro en humedales del centro-occidente de Argentina","resumen":"This paper contributes to scholarship on continental fish exploitation in arid zones in South America by exploring fish consumption by humans in prehispanic times using available zooarchaeological evidence from two wetlands in central western Argentina: Llancanelo and Guanacache lagoons. Analyzing the exploitation of this resource lets us discuss the intensification process that has been proposed for this area. Ichthyoarchaeological and archaeofaunistic information is integrated and compared to reveal that the oldest incidence of fish exploitation (ca. 3000 years B.P.) is from the Llancanelo lagoon. Fish consumption seems to have been practiced since the first occupations in both the wetlands and may reflect an adaptation to the new environment. Contrary to our expectations, temporal trends in abundance and diversity indexes do not show differences between the areas in intensification processes. We conclude that fish represent a major resource for sustenance both in Guanacache and in Llancanelo lagoons, although its exploitation was complemented with consumption of other small animals.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242355,"idioma_id":4,"titulo":"Coevolution of climate, demography and food systems in North and South America","resumen":"One of the less well-understood problems in paleoscience is the role of climate as a modulator of long-term changes in human demography, and, in turn, how changes in human demography influence climate because demography also determines how individuals choose to modify ecosystems. Our workshop compared the long-term interaction between climate, human population change and the organization of social systems to understand the coevolution of Social and Ecological Systems (SES). The feedbacks between climate, ecosystems and social systems may lead to threshold changes in the organization of SES (Anderies et al. 2013). Paleoscience is critical for understanding how and when interactions between climate, ecosystems, and human systems reach threshold-state changes. Such understanding is important because contemporary SES must adapt to population growth and climate change, and insights gained from past SES may informsustainable development in the contemporary world.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242356,"idioma_id":5,"titulo":"De los Carboneros a los Vendimiadores. La Virgen de la Carrodilla y su historia","resumen":"Desde su llegada a Cuyo en el siglo XVIII, la Virgen de la Carrodilla estuvo vinculada con los trabajadores rurales. Primero en las fiestas populares de los cosechadores y después en la Fiesta de la Vendimia con su incorporación al protocolo oficial; al tiempo que fue declarada ?Patrona Celestial de los Viñedos? en 1938 por Monseñor Verdaguer. Este trabajo relata la historia de su devoción, que nace en España, en la sierra aragonesa, donde su imagen fue encontrada por unos carboneros en el siglo XIII y, posteriormente su llegada a las tierras cuyanas, para convertirse en una figura identitaria de Mendoza y la vitivinicultura. Se repasa la resignificación de la devoción en el marco de los cambios históricos, sociales y culturales y, también los cambios iconográficos hasta su vinculación al mural compuesto Coronación de la Virgen de la Carrodilla, obra que conforma su representación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242357,"idioma_id":4,"titulo":"Source Apportionment of PM10-Bound Polycyclic Aromatic Hydrocarbons by Positive Matrix Factorization in Co´rdoba City, Argentina","resumen":"The composition and concentration of Polycyclic Aromatic Hydrocarbons (PAHs) adsorbed on particles smaller than 10 microns (PM10) were analyzed in an urban area during a two-year period from August 2011 to August 2013. Diagnostic ratios (DR) and Positive Matrix Factorization (PMF) were employed to assess emission sources. To discount weather influence, a multiple linear regression model was generated and also a photodecomposition index was calculated for each sample. Despite the fact that mean PM10 levels showed a similar pattern all around the year, majority of PAHs showed higher concentrations during the cold than the warm period, indicating a strong seasonal variation. A 38 % of PAHs variation could be explained by meteorological variables, with wind speed, wind direction and dew point being the significant regressor variables in the model. The source apportionment of PAHs was carried out using PMF although they are photosensitive compounds. To do this the sampling period was separated in warm and cold seasons according to a photodecomposition index and cold period was used. Also, DR were calculated. DR as well as PMF analysis suggested that both gasoline and diesel vehicular emissions, are the main PAHs emission sources in this urban area.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242360,"idioma_id":4,"titulo":"Study of the effect of common infusions on glass ionomers using the PIXE and RBS techniques","resumen":"The effect of four commonly consumed beverages as mineral water, coffee, tea and mate tea on the elemental composition of a commercial glass ionomer was studied using Particle Induced X-ray Emission (PIXE) and Rutherford backscattering (RBS) techniques.We found that after immersion in acidic media, some elements as Al, Si and Na are lost from the glass-ionomer whereas others heavier, as K, Ca and La, increase their concentration at the surface. Although the concentration profiles of Al and Si are different in different media, in all of them the Al:Si ratio was close to unity and remained constant for different periods of immersion in all media. The incorporation of K, Mg and Fe to the surface is found for common infusions while for mineral water the glass-ionomer mainly loses F and Na.The RBS technique showed that immersion in different media produced a modification of the density of the glass ionomer surface layer due to the increment of the concentration of heavier elements at the surface. The thickness of the modified surface layer extends up to 3 µm when the immersion time is seven days and more than 6 µm after 33 days of immersion.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242361,"idioma_id":4,"titulo":"Failure to Recover from Proactive Semantic Interference and Abnormal Limbic Connectivity in Asymptomatic, Middle-Aged Offspring of Patients with Late-Onset Alzheimer&rsquo;s Disease","resumen":"Background: We have obtained previous evidence of limbic dysfunction in middle-aged, asymptomatic offspring of late- onset Alzheimer?s disease (LOAD) patients, and failure to recover from proactive semantic interference has been shown to be a sensitive cognitive test in other groups at risk for LOAD.Objective: To assess the effects of specific proactive semantic interference deficits as they relate to functional magnetic resonance imaging (fMRI) neocortical and limbic functional connectivity in middle aged offspring of individuals with LOAD (O-LOAD) and age-equivalent controls.Methods: We examined 21 O-LOAD and 20 controls without family history of neurodegenerative disorders (CS) on traditional measures of cognitive functioning and the LASSI-L, a novel semantic interference test uniquely sensitive to the failure to recover from proactive interference (frPSI). Cognitive tests then were correlated to fMRI connectivity of seeds located in entorhinal cortex and anterodorsal thalamic nuclei among O-LOAD and CS participants.Results: Relative to CS, O-LOAD participants evidenced lower connectivity between entorhinal cortex and orbitofrontal, anterior cingulate, and anterior temporal cortex. In the offspring of LOAD patients, LASSI-L measures of frPSI were inversely associated with connectivity between anterodorsal thalamus and contralateral posterior cingulate. Intrusions on the task related to frPSI were inversely correlated with a widespread connectivity network involving hippocampal, insular, posterior cingulate, and dorsolateral prefrontal cortices, along with precunei and anterior thalamus in this group. Different patterns of connectivity associated with frPSI were observed among controls.Conclusion: The present results suggest that both semantic interference deficits and connectivity abnormalities might reflect limbic circuit dysfunction as a very early clinical signature of LOAD pathology, as previously demonstrated for other limbic phenotypes, such as sleep and circadian alterations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242362,"idioma_id":4,"titulo":"Relationship between cognitive and sleep-wake variables in asymptomatic offspring of patients with late-onset alzheimer's disease","resumen":"Early neuropathological changes characteristic of late-onset Alzheimer?s disease (LOAD)involve brain stem and limbic structures that regulate neurovegetative functions,including sleep?wake rhythm. Indeed, sleep pattern is an emerging biomarker and apotential pathophysiological mechanism in LOAD. We hypothesized that cognitivelyasymptomatic, middle-aged offspring of patients with LOAD (O-LOAD) would displaya series of circadian rhythm abnormalities prior to the onset of objective cognitivealterations. We tested 31 children of patients with LOAD (O-LOAD) and 19 healthyindividuals without family history of Alzheimer?s disease (control subjects, CS) with basictests of cognitive function, as well as actigraphy measures of sleep?wake rhythm,cardiac autonomic function, and bodily temperature. Unexpectedly, O-LOAD displayedsubtle but significant deficits in verbal episodic memory (Rey Auditory Verbal LearningTest delayed recall 10.6 ± 0.4 vs. 8.6 ± 0.6, t = 4.97, df = 49, p < 0.01) andlanguage (Weschler?s vocabulary 51.4 ± 1.3 vs. 44.3 ± 1.5, t = 2.49, df = 49,p < 0.001) compared to CS, even though all participants had results within theclinically normal range. O-LOAD showed a phase-delayed rhythm of body temperature(2.56 ± 0.47 h vs. 3.8 ± 0.26 h, t = 2.48, df = 40, p = 0.031). Cognitive performancein O-LOAD was associated with a series of cardiac autonomic sleep?wake variables;specifically indicators of greater sympathetic activity at night were related to poorercognition. The present results suggest sleep pattern deserves further study as apotential neurobiological signature in LOAD, even in middle-aged, at risk individuals.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242363,"idioma_id":4,"titulo":"Acute and six-month depression-related abnormalities in the sleep-wake rhythm of cardiac autonomic activity in survivors of acute coronary syndromes","resumen":"ObjectivesTo characterize the influence of changes in depression symptoms severity six months after an acute coronary syndrome (ACS) on the circadian pattern of cardiac autonomic activity, a known independent predictor of adverse outcomes.MethodsOne hundred two patients consecutively admitted to the coronary care unit (CCU) with an ACS were evaluated with a clinical interview (including a psychiatric evaluation for depression), the 21-item Hamilton Depression Scale (HAM-D) for symptom severity and a 24&#8197;h recording of heart rate variability (HRV) at admission and six months post-discharge from the CCU. HRV was measured during wake and sleep (23.00&#8197;h?07.00&#8197;h) with a fast Fourier transform algorithm. We obtained meanRR (mRR), low-frequency HRV (LF) influenced by both sympathetic and parasympathetic activity, high-frequency HRV (HF) determined solely by parasympathetic activity, and LF\/HF ratio as a measure of the sympatho-vagal balance onto the heart (LF\/HF).ResultsUpon admission to the CCU, major depression was present in 44% of subjects. Depression was associated with shorter mRR (higher heart rate), during sleep (p&#8197;<&#8197;0.05). At six months, depression was associated with shorter mRR during wake (p&#8197;<&#8197;0.05) and sleep (p&#8197;<&#8197;0.01), decreased mRR sleep-wake difference (p&#8197;<&#8197;0.05), and lower LF both during wake (p&#8197;<&#8197;0.05) and sleep (p&#8197;<&#8197;0.05). LF and HF changes were related to HAM-D changes 6&#8197;months after the index episode.ConclusionsDepression influenced circadian rhythm of autonomic activity, most notably upon 6-month follow up. Changes in depressive symptom severity after a 6-month observation period were related to changes in HRV known to adversely affect coronary prognosis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242364,"idioma_id":4,"titulo":"CASTE DEVELOPMENTAL PATHWAYS OF Cortaritermes fulviceps (BLATTODEA, TERMITIDAE)","resumen":".","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242366,"idioma_id":4,"titulo":"Histological changes in lung tissues related with sub-chronic exposure to PM2.5","resumen":"Concentration of fine particulate matter (PM2.5) is one of the most important environmental parameters to estimate health impacts attributable to air pollution. Despite the fact there are many studies regarding PM2.5 effects on human health, most of them were performed under conditions that do not simulate the natural particles interaction with the organism. In the present paper, we studied the effects of mammals? sub-chronic exposure to PM2.5 on the lower respiratory tract, addressing realistic exposure conditions to normal urban air. Thus, we exposed Wistar rats under controlled settings to the same normal urban air, with and without particles. Next, we analyzed chemical composition of PM2.5 and lungs samples, performed a histologic examination and run the comet assay to assess genotoxic effects. We found a strong agreement between lung tissues and PM2.5 elemental composition suggesting that metals found in lungs came from the particles inhaled. Histological analysis showed a mild to moderate infiltration, with a reduction of alveoli lumen and increment of alveolar macrophages and periodic acid-Schiff (PAS) (+) cells in treated animals. We also observed an increase in the number of nuclei with comets, mostly comets type 3, with a high DNA fragmentation as well. These results provide strong evidence that sub-chronic exposure to low particle levels, even below the 24&nbsp;h WHO standard, can cause injuries in lungs tissues and DNA damage, as well.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242367,"idioma_id":4,"titulo":"U-Pb and Lu-Hf zircon geochronology of the Ca&ntilde;ad&oacute;n Asfalto Basin, Chubut, Argentina: Implications for the magmatic evolution in central Patagonia","resumen":"The Cañadón Asfalto basin, central Chubut, Argentina, comprises a volcano-sedimentary sequence related to the opening of the Atlantic Ocean during Mesozoic times. The Lonco Trapial, Cañadón Asfalto and Cañadón Calcáreo formations are the main units related to the evolution of this basin. The Las Chacritas and Puesto Almada members are distinguished in the Cañadón Asfalto Formation. LA-HR-ICP-MS U-Pb and Lu-Hf data on zircon were obtained on these units. The Lonco Trapial Formation gave a weighted average age of 172.3 ± 1.8 Ma. A pyroclastic level from the Las Chacritas Member gave a weighted average age of 168.2 ± 2.2 Ma. Two U-Pb concordant ages of 160.3 ± 1.7 Ma on a laminated tuffite and 158.3 ± 1.3 Ma on a pyroclastic level were obtained for the Puesto Almada Member. Two maximum depositional ages constrain the sedimentary provenance areas for the basin: 1) A sample from the Sierra de la Manea range, where a controversial unit related either to the Cañadón Asfalto or to the Cañadón Calcáreo formation occurs, gave an age of 176.6 ± 1.0 Ma. Two younger zircon crystals indicate that this unit may be related to the Cañadón Calcáreo Formation. 2) A sandstone with cross-stratification from the Puesto Almada Member gave a maximum depositional age of 173.6 ± 6.4 Ma. In terms of U-Pb and Lu-Hf isotopes, two magmatic events are identified in central Patagonia: the Mamil Choique magmatic event characterized by negative &#949;Hf values around &#8722;5.0 and representing recycling during Permian times of Mesoproterozoic crust (TDM of &#8764;1.5 Ga), and the Cañadón Asfalto magmatic event with negative (&#8722;8.2) to positive (+4) &#949;Hf values and Meso- to Neoproterozoic TDM between 1.5 and 0.8 Ga. The younger event is characterized by three main cycles: C1 related to the Lonco Trapial magmatism, C2 to the Las Chacritas volcanism, and C3 to the Puesto Almada volcanism. These cycles are related with Marifil, Chon Aike and El Quemado formations volcanics events of Patagonia and the Neuquén Basin during the Mesozoic.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242369,"idioma_id":4,"titulo":"Likelihood Ratio Test for Partial Sphericity in High and Ultra-high Dimensions","resumen":"Due to space constraints, we have placed in this document additionalgures and tables to further illustrate results for the article Forzani et al. [1].Section 2 reports simulations for a variety of values of p, d and m. They showhow the dierence between the asymptotic distribution and the true one isaected by how the values of the spikes compare with the threshold. We alsocompare the classical chi-square approximation, for p xed, with the onepresented in the paper for p and m growing simultaneously. In Section 3 andSection 4 we present simulations based on the models given by Passemier andYao [2] and on those presented in Section 4.2 and 6.1 of [1], but with dierentvalues of p, m and p=m. In Section 3 we report the choice of dimension ofthe spike model using likelihood ratio test and in Section 4 the dimensionsbased on the the penalized version (HD-MDL).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242376,"idioma_id":5,"titulo":"Leptospirosis: una enfermedad latente","resumen":"Existen ciertas condiciones que favorecen la viabilidad de las leptospiras en el medio ambiente, tales como humedad, suelos anegadizos con pH neutro o ligeramente alcalino y temperaturas cálidas. En áreas con lagunas, riachuelos, bebederos y agua de bebida en general, que concentran animales, son focos posibles de leptospirosis. Desde el punto de vista de la salud pública, la importancia está asociada al riesgo laboral en personas que realizan tareas que involucran contacto directo o indirecto con animales o productos animales.Cada caso del Servicio de diagnóstico de Sanidad Animal de la estación experimental INTA Mercedes, está constituido por una muestra o conjunto de muestras (biológicas o no biológicas) obtenidas de un animal o grupo de animales afectados por un problema de baja productividad atribuible a un factor sanitario, y pertenecientes a un establecimiento. Por lo cual, éstas son remitidas para su estudio con el fin de obtener, confirmar o descartar un diagnóstico. Los diagnósticos se realizaron mediante análisis de laboratorio, observación clínica y estudio post mortem, o por una combinación de métodos. Los resultados obtenidos fueron cargados en una base de datos denominada EpiDiagno perteneciente al laboratorio. Mediante esta base de datos, se realizó un estudio retrospectivo considerando los casos registrados en la EEA INTA Mercedes como positivos a leptospirosis bovina desde el año 2010 al 2016. Los casos positivos, estuvieron relacionados con abortos, mortalidad de terneros o positivos por diagnostico serológico. A su vez se tuvieron en cuenta las precipitaciones anuales (mm) durante el período 2010-2016 (Observatorio Agro-meteorológico. EEA INTA Mercedes, 2017).Por otra parte, y durante el año 2017, se realizaron muestreos en campos dentro de la provincia de Corrientes, los cuales cuentan con plan sanitario obligatorio, sin embargo, no realizan vacunación contra leptospirosis. Dichos establecimientos poseen explotaciones de tipo mixta (bovino-ovino). Las muestras recolectadas fueron sangre y orina, tomándolas de forma pareada con intervalos de 15-20 días entre muestreos. Finalmente, los análisis se realizaron en el Laboratorio de Red L262 LA0127 INTA EEA Mercedes. Mediante los datos obtenidos y teniendo en cuenta las precipitaciones registradas hasta el momento para el año 2017, se realizó el presente análisis.Al realizar el análisis e interacción de los casos positivos de leptospirosis con las precipitaciones registradas se pudo determinar que el mayor número de casos se presentaron durante los meses de mayo. En el año 2017, en coincidencia con la época de mayores precipitaciones, se presentaron 5 casos positivos a leptospirosis bovina en el mes de mayo. Sin embargo, al realizar el análisis de las precipitaciones con los casos registrados de leptospirosis bovina durante 2010-2016, no se observó una relación entre mayor precipitación (mm) y presencia de casos clínicos.Dicha situación podría estar relacionada a que los datos fueron tomados del registro del laboratorio, sin realizar muestreos dirigidos y seriados. Los datos obtenidos correspondían a casos clínicos que llegaban a la experimental, pudiendo existir casos positivos cuyas muestras no eran remitidas al laboratorio, y por lo tanto diagnosticadas. Según Carrica (2007) un 67% de los laboratorios mencionan la ausencia de un segundo muestreo serológico necesario para la seroconversión, como una de las dificultades que impiden llegar al diagnóstico de la leptospirosis. Una sola muestra es de utilidad diagnóstica limitada. No se puede diferenciar, si el nivel de los anticuerpos se debe a la vacunación reciente, a una condición endémica en el rodeo, o a una exposición cercana con el agente y, por lo tanto, la causa de abortos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242382,"idioma_id":5,"titulo":"Educación y migración latinoamericana. Interculturalidad, derechos y nuevas formas de inclusión y exclusión escolar","resumen":"La situación educativa de los migrantes latinoamericanos seconstituyó como tema de interés para la investigación y la definición depolíticas en tiempos recientes. Esta problemática invita a repensar losmandatos uniformizadores con que el sistema educativo se estructuró, el alcancede las innovaciones, las expectativas de las familias y las organizacionesmigrantes, y la situación de las llamadas segundas generaciones. Comenzamos con una breve recorrida histórica que permiteadvertir la alternancia de paradigmas de asimilación, integración e inclusióncon que el sistema educativo se posicionó frente a los que definió comoextranjeros, el peso del nacionalismo escolar y el modo en que los migrantes(sobre todo los migrantes latinoamericanos) fueron definidos como otros. Nos referimos también a losnuevos discursos de derechos humanos, inclusión e interculturalidad y el modoen que se articulan con viejos mandatos. Advertimos la complejidad con que el discurso de lainclusión se presenta en las escuelas con alto componente de población migrantelatinoamericana. Múltiples indicios nos permiten sostener que, aún con avancesen las políticas y la multiplicación de estrategias en las escuelas, lapresencia de los migrantes latinoamericanos y de sus descendientes puedecaracterizarse en muchos sentidos como una forma&nbsp; subordinada de inclusión.Atendiendo a las expectativas de los colectivos migrantes,nos centramos en la situación de la población boliviana con la que venimostrabajando hace años. Sus demandas hacia el sistema aparecen fuertementeestructuradas por la doble apuesta de las familias y organizaciones migrantespor incluirse en la sociedad argentina en condiciones de mayor igualdad y porsostener su distintividad como colectivo.&nbsp;En la segunda parte del texto nos detenemos en algunasreflexiones más situadas en el espacio donde hace algunos años desarrollamosnuestro trabajo de campo: un barrio de la provincia de Buenos Aires con un altoporcentaje de población procedente de Bolivia y sus descendientes. En este espacio registramos sostenidasapuestas por la igualdad y la inclusión de las familias y organizaciones demigrantes, que se traducen en proyecciones de que sus hijos puedan realizartrayectos escolares largos y prácticas para acceder y mantenerse en lo queconsideran 'una buena escuela del barrio'. Asimismo registramos fuertesexpectativas de continuidad del colectivo que trasladadas a las jóvenesgeneraciones muchas veces se ponen en tensión con los modelos de sujeto y los mandatoseducativos hegemónicos. Reconstruimos esto en dos ámbitos que funcionan comoespacios de marcación de la pertenencia: las fiestas y el trabajo.En las escuelas primarias de la localidad registramos elmantenimiento del mandato de identificación con lo nacional argentino, juntocon propuestas de valorización cultural y la legitimación de nuevas presenciasy voces (por ejemplo en las fiestas escolares). En las escuelas secundarias se advierten fuertescontradicciones con la valorización del trabajo de los jóvenes que se registranen contextos familiares y comunitarios. Se advierten en definitiva tanto los intentos como laslimitaciones de las escuelas argentinas para incluir y trabajar con lacondición transnacional de vida de los jóvenes migrantes y también de muchos delos hijos (e incluso los nietos) de los migrantes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242385,"idioma_id":4,"titulo":"A methodology to infer and refactor an object-oriented model from C applications","resumen":"When analyzing legacy code, generating a high-level model of an application during the reverse engineering process helps the developers understand how the application is structured and how the dependencies relate the different software entities. Within the context of procedural programming languages (such as C), the existing approaches to get a model of the code require documentation and\/or implicit knowledge that stakeholders acquire during the software building. These approaches use the code itself to build a syntactic model where we see the different software artifacts, such as variables, functions, and modules. However, there is no supporting methodology to detect and analyze if there are relationships\/dependencies between those artifacts, such as which variable in a module is declared using an abstract data type described in another one, or which are the functions that are using parameters typed with an abstract data type; or any design decision taken by original developers, such as how the developer has implemented functions in different modules. On the other hand, current developers use object-oriented (OO) paradigm to implement not only business applications but also useful methodologies\/tools that allow semiautomatic analysis of any application. We must remark the legacy procedural code still has worth and is working in several industries, and as any evolving code, the developers have to be able to perform maintenance tasks minimizing the limitations offered by the language. Based on useful properties that the OO paradigm (and their supporting analysis tools) provide, such as UML models, we propose M2K as a methodology to generate a high-level model from legacy procedural code, mainly written in Ansi C. To understand how C-based applications were implemented is not a new problem in software reengineering. However, our contribution is based on building an OO model and suggesting different refactorings that help the developer to improve it and to eventually guide a new implementation of the target application. Specifically, the methodology builds cohesive software entities mapped from procedural code and makes the coupling between C entities explicit in the high-level model. The result of our methodology is a set of refactored class candidates: a structure that groups a set of variables and a set of functions obtained from the C applications. Based on the class candidate model, we propose refactorings based on OO design principles to improve the design of the application. The most relevant design improvements were obtained with algorithm abstraction by applying the strategy pattern, attributes\/methods relocalization, variables types generalization, and removing\/renaming methods\/attributes. Besides a methodology and the supporting tool, we provide 14 case studies based on real projects implemented in C, and we showed how the results validate our proposal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242388,"idioma_id":5,"titulo":"La relevancia de los coreográfico en el Teatro Musical de Buenos Aires","resumen":"El Teatro Musical es una forma de arte que conjuga el teatro, la música y la danza. Es esta conjunción de lenguajes la que ha permitido denominar al musical como Arte Integral, que con los años ha llevado al hombre a probar al máximo sus capacidades expresivas. El Teatro Musical, o sencillamente el musical, es un género atado a la necesidad de comunicar permanentemente eventos actuales, obligado a fusionar diversas tendencias y estilos acordes al contexto de la época. Debido a esta fusión, el Teatro Musical es actualmente uno de los más grandes géneros del arte debido a su amplio recorrido por sucesos históricos, psicológicos y sociológicos. Los elementos más importantes con los que trabaja el Teatro Musical son el libro y la música, pero a esto hay que sumarle su parte coreográfica. Ésta puede plantearse de una forma muy diferente a los modelos clásicos del género; incluso puede parecer que no está incluida, pero de hecho, en los desplazamientos de los actores en el espacio se puede observar un diseño coreográfico que la hace diferente a una obra teatral convencional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242389,"idioma_id":5,"titulo":"Derivaciones del principio de acceso al consumo sustentable en las relaciones de consumo","resumen":"-","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242400,"idioma_id":4,"titulo":"Alterations on bone resorption of alveolar bone caused by lead poisoning. Study histomorphometric under different experimental conditions","resumen":"The aim of this study was to determine the effect lead poisoning on bone resorption under different experimental conditions. Wistar rats were assigned to one of the following groups: I control, II lead poisoning, III experimental periodontitis (EP) and IV, lead poising and EP. Intoxication was achieved in groups II and IV by administering Pb acetate in a concentration of 1000 ppm in drinking water for 60 days. EP was induced in groups III and IV by placing cotton ligatures around the neck of the lower first molars at the 57 day experience.  On day 60, the animals were sacrificed and the hemi-mandibles were processed for light microscopy. Mesial-distalsection of mandibular firdt molr were obteined and stained with H-E. the following parameters were determinated in the radicular bone: 1) bone loss (BR). 2) Percentages of bone resorption surfaces (RO) on mesial and distal aspect of the interradicular bone. 3) Osteoclast number (N.Oc) on mesial and distal aspect of the interradicular bone. 4) BT\/TV. 5) Trabecular thickness (Tb.Th). 6) Number of trabeculae (Tb.N). 7) Trabecular separation (Tb.Sp). Data were analyzed with the Kruskal-Wallis test and post hoc Kolmogorov-Smirnov. Results: BL [mm], BR mesial [mm], BR distal [mm], N.Oc mesial, N.Oc distal, were significantly lower in group III, respect group I II y IV. Tb.Th [mm] was significantly lower in group respect II and in III respect IV. Tb_Sp [mm] was significantly lower in groups I; II y IV. The results suggest that Pb poisoning high dose of 1000 ppm, alters bone resorption of alveolar bone, both in normal and pathological conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242401,"idioma_id":5,"titulo":"Patógenos como Rhizoctonia solani Kühn afectan al cultivo de la soja en el norte bonaerense. Recomendaciones para un control integrado.","resumen":"Rhizoctonia solani Kühn [Teleomórfica Thanatephoruscucumeris (Frank) Donk] es el principal patógeno delcomplejo dumping off. Este patógeno afecta al cultivo desoja en el norte de la provincia de Buenos Aires y produce laenfermedad denominada Tizón por Rhizoctonia. Durante dosaños (2014 y 2015), Lavilla e Ivancovich relevaron 80 lotes poraño en esta zona bonaerense. Los resultados demostraronque entre el 50% (2015) y 75% (2014) de los lotes registranplántulas de soja afectadas por R. solani. Sin embargo, en2015, cuando las precipitaciones en etapas tempranas (VE,VC, V1...V6 [Fehr y Caviness, 1971]) fueron superiores a lasnormales, estacondición ambiental -junto con temperaturasmoderadas-, fue predisponente para la aparición de otraenfermedad del complejo dumping off: la Podredumbre dela raíz y tallo causada por Phytophthora sojae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242402,"idioma_id":5,"titulo":"Soja protegida frente al tizón de la vaina","resumen":"El tizón de la vaina causado por Phomopsis sojae (TeleomorfoDiaporthe phaseolorum var. sojae) sinonimia PhomopsisLongicolla, es la enfermedad más importante que afecta a lagerminación de la semilla de soja. P. sojae puede colonizartan sólo al tegumento o llegar hasta los cotiledones y ejeembrional. Dependerá del estado fenológico al momento dela infección así comode las situaciones climáticas y demorasen la cosecha. Este patógeno sobrevive en el rastrojo (tallo,semillas y vainas) mediante picnidios que pueden produciresporas (conidios) de dos tipos: alfa y beta.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242403,"idioma_id":5,"titulo":"Revisión operativa y ambiental de las plantas de ósmosis inversa en la Provincia de La Rioja, Argentina","resumen":"Un estudio realizado a pedido del instituto Provincial del Agua de La Rioja, recomienda la revisión operativa de sus plantas de ósmosis inversa, teniendo en cuenta los aspectos ambientales de su funcionamiento.Este grupo se ha abocado a la tarea habiendo realizado hasta este momento el relevamiento de la totalidad de estas plantas y ha zonificado el estudio según un criterio de circuitos viales a recorrer, para optimizar los tiempos de visita y recolección de datos.Se ha evaluado la situación operativa de tres plantas del sur de la provincia.  Se recomienda hasta el momento un procedimiento para la operación de cada planta revisada y realizar el tratamiento de las aguas de rechazo, que hasta el momento se vierten en las inmediaciones. El contenido salino varía en cantidad y calidad.Por el momento se  recomienda el tratamiento de las aguas de rechazo por evaporación y la disposición final de los productos, en este caso en las salinas del sur, límite de La Rioja con San Juan.  La composición de las sales se asemeja a las que se emplean en los suplementos dietarios del ganado. Una alternativa para la disposición de las sales es su aprovechamiento para la fabricación de los panes que se emplean en  la dieta para  ganadería, una actividad importante para la economía de la provincia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242406,"idioma_id":4,"titulo":"Short-term chromium (VI) exposure increases phosphorus uptake by the extraradical mycelium of the arbuscular mycorrhizal fungus Rhizophagus irregularis MUCL 41833","resumen":"Hexavalent chromium is a potent carcinogen, whilephosphorus is an essential nutrient. The role of arbuscular mycorrhizal fungi &nbsp;(AMF) &nbsp;in the uptake of P is well known and was alsoreported, at low levels, for Cr. However, it is unclear whether the uptake ofCr can impact the short­-term uptake dynamics of P since both elements have a similarchemical structure &nbsp;and may thuspotentially compete with each other during the uptake process. This studyinvestigated the impact of Cr(VI) on short-term P uptake by the AMF Rhizophagus irregularis &nbsp;MUCL 41833 in Medicago truncatula. Bi-compartmented Petri plates were used tospatially separate a root compartment (RC) from a hyphal compartment (HC) usinga whole plant in vitro culture system.The HC was supplemented with Cr(VI). Chromium(VI) as well as total Cr and P weremonitored during 16 h within the HC and their concentrations determined by theend of the experiment within roots and shoots. Our results indicated that the uptake and translocationof Cr from hyphae to roots was a fast process: roots in which the extraradicalmycelium (ERM) was exposed to Cr(VI) accumulated more Cr than roots of which theERM was not exposed to Cr(VI) or was dead. Our results further confirmed that deadERM immobilized more Cr than alive ERM. Finally our results demonstrated that theshort exposure to Cr(VI) was sufficient to stimulate P uptake by the ERM andthat the stimulation process began within the first 4 h of exposure. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242410,"idioma_id":5,"titulo":"Territorio y políticas sociales en los hogares populares del conurbano bonaerense","resumen":"En este artículo se persiguen dos objetivos: por un lado,analizar el papel de las políticas sociales, -en particular las detransferencias monetarias- en las estrategias de reproducción social de loshogares, considerando la que propone de una reconfiguración del papel quejuegan esas políticas en la matriz de estrategias a partir de la masificación ypeso por el monto de los ingresos en el último lustro. El segundo objetivo es retomar el planteo de Esping-Andersen(1993), quien sostiene que las políticas sociales deben ser analizadasconsiderando la forma que asumen los arreglos 'familia-mercado-Estado' ,postulando que esa triada es insuficiente para el análisis de la economíapopular que estudiamos, ya que no puede comprenderse la configuración de lapolítica social sin considerar el papel de las matrices político territoriales.Por ello, para el caso específico de la economía popular del Conurbano, el análisisde la política social debe considerar los arreglos 'familia-mercado-Estado-territorio'.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242411,"idioma_id":4,"titulo":"Characterization of the As(III) tolerance conferred by plant growth promoting rhizobacteria to in vitro-grown grapevine","resumen":"The element As is ubiquitous in nature and it has been reported all over the world in irrigation and drinking water. Bacterization with Plant Growth Promoting Rhizobacteria (PGPR) may increase plant growth and minimize stress and toxic effects of many abiotic factors. The aim of this study was to test the ability of As(III) tolerant PGPR isolated from grapevine rhizosphere to minimize As toxic effect in in vitro grapevine cv. Malbec. Nine bacterial strains were tested adding different NaAsO2 concentrations to the medium. According to their As(III) tolerance and PGP traits, Bacillus licheniformis, Micrococcus luteus and Pseudomonas fluorescens were selected. B. licheniformis and M. luteus (both highly tolerant to As(III)) had the ability to produce siderophores in presence of high NaAsO2 concentration, but only M. luteus solubilized phosphates and fixed N2 under such condition. In vitro-grown grapevine plants were bacterized with the PGPR and added or not (controls) with NaAsO2. M. luteus increased plant biomass and protein content, while B. licheniformis only increased plant biomass, and P. fluorescens, less tolerant to As(III), had no effect. Depending on the treatments combination antioxidant enzymes were differentially affected. In presence of NaAsO2, all the strains increased catalase; B. licheniformis enhanced ascorbate peroxidase, while M. luteus and P. fluorescens augmented peroxidase activity. The results showed a significant decrease of NaAsO2 toxic effect in in vitro grapevines inoculated with M. luteus, suggesting that this bacterium is a good candidate for bioremediation towards As(III) contamination.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242412,"idioma_id":4,"titulo":"Grapevine tissues and phenology differentially affect soluble carbohydrates determination by capillary electrophoresis","resumen":"Soluble carbohydrates distribution depends on plant physiology and, among other important factors, determines fruit yield and quality. In plant biology, the analysis of sugars is useful for many purposes, including metabolic studies. Capillary electrophoresis (CE) proved to be a powerful green separation technique with minimal sample preparation, even in complex plant tissues, that can provide high-resolution efficiency. Matrix effect refers to alterations in the analytical response caused by components of a sample other than the analyte of interest. Thus, the assessment and reduction of the matrix factor is fundamental for metabolic studies in different matrices. The present study evaluated the source and levels of matrix effects in the determination of most abundant sugars in grapevine tissues (mature and young leaves, berries and roots) at two phenological growth stages. Sucrose was the sugar that showed the least matrix effects, while fructose was the most affected analyte. Based on plant tissues, young leaves presented the smaller matrix effects, irrespectively of the phenology. These changes may be attributed to considerable differences at chemical composition of grapevine tissues with plant development. Therefore, matrix effect should be an important concern for plant metabolomics.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242414,"idioma_id":4,"titulo":"Failure Analysis of a Damaged Direct Injection Diesel Engine Piston","resumen":"This work deals with the piston failures found in diesel engines functioning in light trucks. The failure was a hole inside the bowl located at the top of the piston, which is the combustion chamber of the engine. This hole progressed and finds its way out between the second and third rings. The operational characteristics of the engine were analyzed in order to elucidate the probable acting failure mechanisms. For the evaluation, obviously were assessed the damaged pistons but also pistons of the same engine without the mentioned failure and a new piston. Different studies and measurements were carried out such as microstructural morphologies and transformations, hardness, fracture surface analysis and chemical composition. The piston design, the material used and the operational conditions (thermal and mechanical) were studied with the purpose of determining the failure origin. It was concluded that thermomechanical fatigue along with some degree of degradation suffered by the material is responsible of the reported failure.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242415,"idioma_id":4,"titulo":"Molecular characterization of diarrheagenic Escherichia coli isolated from vegetables in Argentina","resumen":"AbstractThe aim of this study was to investigate the prevalence of diarrheagenic E. coli strains in vegetables from the humid Pampa region, Argentina, and to determine the occurrence of serotypes and virulence genes in the isolates. A total of 373 fresh vegetable samples obtained from 41 different geographical points were examined. E. coli was detected in 38.6% of the samples. Ten isolates could be obtained from 14 samples presumptively positive for diarrheagenic E. coli: 8 were identified as atypical Enteropathogenic E. coli (aEPEC) and 2 as Verocytotoxigenic E. coli (VTEC). Lettuce and beet were the vegetables most frequently contaminated with pathogenic E. coli. The isolates belonged to serotypes O1:H7, O28:H19, O39:H40, O86:H31, O132:H8, O139:H20, O178:H7 and O178:H19, some of which reportedly have caused human illness, and one isolate resulted non typeable. Taking into account the distribution of 16 nle genes, 7 profiles were detected. On the other hand, all tested isolates harbored the gene encoding for the adhesin HcpA. Other adhesion related genes were also identified: ecpA and elfA were detected in 90%, lpfA0113 in 60%, and ehaA in 50% of the isolates meanwhile ihaA was only observed in O178:H19 isolate. This VTEC isolate harbored, also, Cdt-V toxin and megaplasmid encoding genes such as espP, subA and epeA and exhibited a strong cytotoxic effect. These data is the first molecular E. coli report that confirms the presence of E. coli pathotypes circulating among vegetables in Argentina. Genetic characterization showed that in addition to eae or vtx genes, isolates obtained from vegetables harbored genes encoding other toxins, adhesins, and components related to the type III secretion system that could contribute to their virulence. In conclusion, this research shows that vegetables in Argentina may be the source of VTEC and EPEC infections in the community and therefore, they should be considered as vehicles for transmission of these potentially pathogenic bacteria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242418,"idioma_id":4,"titulo":"Searching for New Sources of Phytopharmaceuticals in  Native  Valeriana  from Patagonia, Argentina","resumen":"The  study  of  new  sources  of  phytopharmaceuticals  is  an interesting field of research and in many cases the selection of new species to study are based on plants that have been used since ancient times by different ethnic groups in each regions of the world. One of the genus of cosmopolitan distribution with many species used for medicinal purposes around the world is Valeriana L. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242421,"idioma_id":4,"titulo":"Nm F2 trends at low and mid latitudes for the recent solar minima and comparison with IRI-2012 model","resumen":"The ionospheric electron density peak (NmF2) is analyzed for the recent minima of solar activity for two mid-latitude stations, Rome (41.8_N, 12.5_E, geomagnetic latitude 41.7_N, Italy) and Gibilmanna (37.9_N, 14.0_E, geomagnetic latitude 37.6_N, Italy), and for the low-latitude station of Tucuma´n (26.9_S, 294.6_E, geomagnetic latitude 17.2_S, Argentina), located in the south ridge of the equatorial ionization anomaly. An inter-minima comparison reveals that from an ionospheric point of view the last minimum of solar activity (minimum 23\/24) was peculiar, with values of NmF2 lower than those recorded during the previous minima for all the stations and all thehours of the day. A more pronounced decrease is observed at Tucumán than at Rome and Gibilmanna. The study of the winter and semiannual anomaly shows that at mid-latitude stations the winter anomaly is not visible only for the years 2008 and 2009, which represent the deeper part of the prolonged and anomalous last solar minimum. The same is for the semi-annual anomaly. A comparison with the version 2012 of the International Reference Ionosphere model (IRI) is also carried out. The results reveal that for low solar activity the model works better at mid latitudes than at low latitudes, confirming the problems of IRI in correctly representing the low-latitude ionosphere.Nevertheless, using as input updated values of the solar and geomagnetic indices, no loss of accuracy is detected in the IRI performances for the last solar minimum with respect to the previous ones, both at mid and low latitudes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242422,"idioma_id":4,"titulo":"NeQuick 2 total electron content predictions for middle latitudes of North American region during a deep solar minimum","resumen":"The performance of NeQuick 2 model in computing the vertical total electron content (VTEC) over a wide region placed at middle latitudes of North America during the deep solar minimum that occurred in 2008 has been checked. The long term relationship between EUV irradiance and F10.7 solar flux has changed markedly during the cycle 23\/24 minimum with EUV levels decreasing more than expected from F10.7 proxy. A decrease ofionization in the ionosphere could have occurred. Thus, it could be expected that the models overestimate the value of ionospheric parameters for that deep solar minimum. For this study a high density VTEC data grid that covers the Continental United States (CONUS) has been compared with monthly median maps constructed with NeQuick 2.The results show that NeQuick 2 generally gives good predictions for the region which lies between 35°N to 50°N suggesting that nothing exceptional was happening during the 2008 minimum in terms of VTEC NeQuick2´s predictive capabilities. Taking into account that the modeled value is obtained by integration in height of the electron density profile, NeQuick2 would be assuming an inadequate profile for the few highest deviations observed, between 30°N and 35°N. Overall, the model does not give significant overestimation of VTEC as could be expected.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242426,"idioma_id":4,"titulo":"Equinoctial spread-F occurrence at low latitudes in different longitude sectors under moderate and high solar activity","resumen":"A comparative study aimed to investigate the equatorial and low-latitude spread-F occurrences for moderate solar activity (MSA) and high solar activity (HSA), was carried out considering concurrent observations made in some ionospheric stations, which identify three separate longitudinal sectors: Chiang Mai (CGM; 18.8 N, 98.9 E, mag. Lat. 13.2 N) and Chumphon (CPN; 10.7 N, 99.4 E, mag. Lat. 3.2 N), Thailand; Palmas (PAL; 10.2 S, 311.8 E, mag. Lat. 0.9 S) and S~ao Jose dos Campos (SJC; 23.2 S, 314.1 E, mag. Lat. 14.0 S), Brazil; Tucuman (TUC; 26.9 S, 294.6 E, mag. Lat. 16.8 S), Argentina.Spread-F phenomena recorded during the equinoctial months of September and October 2010, March and April 2011, for MSA, March and April 2014, September and October 2014, for HSA, were classified in two differentmodes: range spread-F (RSF) and frequency spread-F (FSF). The satellite trace (ST) occurrence was also investigated as possible precursor of spread-F events. When comparing the results of equatorial (CPN and PAL) and low-latitude (CGM, SJC, and TUC) stations, some common features independently of the solar activity emerge: (1) a prevalence of RSF signatures is observed in the time interval 20:00?03:00 LT, while FSF occurrences prevail in the time interval 03:00?06:00 LT; (2) STs are confirmed to be a possible precursor of RSF occurrences. For HSA, at equatorial latitudes, spread-F occurrences in the Thai sector (CPN) are higher than those observed in the Brazilian sector (PAL).When comparing the results of low-latitude stations of CGM, SJC, and TUC some unusual aspects characterizing the morphology of spread-F occurrences emerge: (1) contrary to the Thai and Argentine sectors, in the Brazilian sector (SJC), RSF and FSF appearances in September, for HSA, are observed with relatively long persistence times between about 03:00-06:00 LT and 01:00-03:00 LT respectively, while balanced RSF and FSF occurrences with short persistence times are observed for months for MSA; (2) a prevalence of FSF at CGM during the first half ofSeptember for MSA, never observed in the Brazilian and Argentine areas.During years of LSA and MSA common morphological aspects are found at CGM and SJC, that is a predominance of FSF, with the lowest persistence times characterizing SJC. This suggests that the low-latitude behaviour ofspread-F occurrences, under different levels of solar activity, at least in the longitude sectors here analysed, can beto a some extent generalized.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242430,"idioma_id":4,"titulo":"Changes in [3H]-ouabain and [3H]-neurotensin binding to rat cerebral cortex membranes after administration of antipsychotic drugs haloperidol and clozapine. Peptides x 89:82-89.","resumen":"Evidences indicate the relationship between neurotensinergic and dopaminergic systems. Neurotensin inhibits synaptosomal membrane Na+, K+-ATPase activity, an effect blocked by SR 48692, antagonist for high affinity neurotensin receptor (NTS1) type. Assays of high affinity [3H]-ouabain binding (to analyze K+ site of Na+, K+-ATPase) show that in vitro addition of neurotensin decreases binding. Herein potential interaction between NTS1 receptor, dopaminergic D2 receptor and Na+, K+-ATPase was studied. To test the involvement of dopaminergic D2 receptors in [3H]-ouabain binding inhibition by neurotensin, Wistar rats were administered i.p.with antipsychotic drugs haloperidol (2 mg\/kg) and clozapine (3, 10 and 30 mg\/kg). Animals were sacrificed 18 hours later, cerebral cortices harvested, membrane fractions prepared and high affinity [3H]-ouabain binding assayed in the absence or presence of neurotensin at a 10 micromolar concentration. No differences versus controls for basal binding or for binding inhibition by neurotensin were recorded, except after 10 mg\/kg clozapine. Rats were administered with neurotensin (3, 10 y 30 µg, i.c.v.) and 60 min later, animals were sacrificed, cerebral cortices harvested and processed to obtain membrane fractions for high affinity [3H]-ouabain binding assays. Results showed a slight but statistically significant decrease in binding with the 30 µg neurotensin dose. To analyze the interaction between dopaminergic D2 and NTS1 receptors, [3H]-neurotensin binding to cortical membranes from rats injected with haloperidol (2 mg\/kg, i.p.) or clozapine (10 mg\/kg) was assayed. Saturation curves and Scatchard transformation showed that the only statistically significant change occurred in Bmax after haloperidol administration. Hill number was close to the unit in all cases. Results indicated that typical and atypical antipsychotic drugs differentially modulate the interaction between neurotensin and Na+, K+-ATPase. At the same time, support the notion of an interaction among dopaminergic and neurotensinergic systems and Na+, K+-ATPase at central synapses.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242435,"idioma_id":5,"titulo":"Perfil de la mortalidad por homicidios durante el periodo 1990-2012 en la Provincia del Chaco y en la República Argentina","resumen":"La tasa promedio global de homicidios es de 6.2 por cada 100 mil habitantes y, en Argentina, ocurren cincohomicidios por cada 100 mil habitantes. El objetivo del presente trabajo fue describir la tendencia de la mortalidadpor homicidios en la provincia del Chaco y la Argentina. En cuanto a los materiales y métodos, utilizamos el tipo deestudio ecológico empleando como fuente de datos los Anuarios de la Dirección de Estadísticas Sanitaria. Losresultados arrojaron que se produjeron 1.388 y 37.785 muertes por homicidios en la provincia del Chaco -conprevalencia de mayor riesgo de muerte por homicidios- y en la Argentina. Las tasas de mortalidad específicas poredad fueron, en el país, mayores en las personas de 15 a 24 años, sin embargo, en la provincia fue mayor en elgrupo etáreo de 25 a 34 años en donde el sexo masculino presentó 5,5 veces más riesgo de morir por homicidio.En conclusión, la provincia del Chaco presenta mayor riesgo de muertes por homicidios que las tasas nacionales,aunque existe una tendencia al descenso.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242436,"idioma_id":4,"titulo":"Tuning properties of carbon surfaces functionalized with amino-ended dendron layers by exploring their supramolecular","resumen":"An effective tailoring of carbon surfaces functionalized with a first-generation amino-ended dendrons was achieved by a simple self-assembly strategy. The morphology, as well as the viscoelastic and electrical properties of the modified surfaces were characterized at a micro-nanoscale level, by Cyclic Voltammetry (CV), Electrochemical Impedance Spectroscopy (EIS), Atomic Force Microscopy (AFM) and Kelvin Probe Force Microscopy (KPFM). Thermodynamic parameters of the adsorption were investigated by EIS, studying the blocking properties of the modified surfaces towards the redox conversion of [Fe(CN)6]3 &#8722;\/[Fe(CN)6]4 &#8722;. AFM images were used to characterize the topography of the modified surfaces and also their viscoelastic properties by the acquisition of phase images. &#960;-&#960; stacking interactions between dendrons and the carbon surface control the aggregation at low coverages, while forces of intermolecular Hydrogen-bond among dendrons appear at high coverages leading to more compact regions. The implications of the amino-ended dendron layer on the electrical properties of the modified surface have been analyzed through KPFM in comparison with nitro-ended dendron films, showing a decrease of the local contact potential difference after the incorporation of molecules having electron-donor (&#8722; NH2) functional groups, in contrast with the increase showed for molecules with electron-acceptor (&#8722; NO2) ones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242437,"idioma_id":5,"titulo":"Influencia de la suplementación del medio de maduración con Cisteamina y EGF en la supervivencia de embriones bovinos producidos in vitro","resumen":"This study evaluated the effect of epidermal growth factor (EGF) addition on the maturation medium (IVM) on the percentage of oocytes in metaphase II, the embryonic development and the survival of cryopreserved blastocytes through slow freezing with ethylene glycol (EG). The oocytes obtained from ovaries collected at an abattoir (n = 1110) were processed in 8 replicates and distributed into three groups (Control Group: no EGF, Group I: 100 ng\/ml EGF and Group II: 50 ng\/ml EGF) to obtain approximately 115 frozen-thawed embryos per group. The oocytes were matured during 24 h in TCM-199 medium with FSH-rh, sodium pyruvate, gentamicin and FBS, distributed in the respective groups at 38.8 ºC and 5.5 % CO2. Fertilization was carried out for 18-24 h in IVF-SOF medium and semen selected by percoll gradient. The presumed zygotes were cultivated in SOF-Citrate medium. The Grade I embryos were frozen and thawed one week later. The addition of 50 ng\/ml and 100 ng\/ml of EGF favored oocyte nuclear maturation (P  0.05).  The results demonstrated that addition of EGF to the IVM medium did not influence embryonic survival to freezing.Keywords: Oocytes, IVM medium, EGF, embryos, freezing.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242438,"idioma_id":4,"titulo":"Lightweight Semantic based Approach to Assess Readability of Web Service Interfaces [Latindex]","resumen":"A Web Service has an interface described in a machine-processable format (specifically WSDL). Service providers expose their services by publishing their WSDL documents. Service consumers can learn about service capabilities and how to interact with services. Service descriptions (WSDL documents) should be ideally understood easily by service stakeholders so that the process of consuming services is simplified. In this work we present a practical metric to quantify readability in WSDL documents. We adapted and extended an existing ontology-based semantic readability metric to focus on WSDL documents by using WordNet as a lightweight concept hierarchy. We have validated our approach by performing both qualitative and quantitative experiments. The first one consists of a controlled survey with a group of service consumers. The results showed that consumers (software engineers) required less time and effort to analyze WSDL documents with higher readability values. The second experiment compares our approach with two ontology-based approaches. The third experiment compares the readability values of a dataset of real- life service descriptions before and after rewriting them. The results showed the effectiveness of our approach to assess readability of Web Services interfaces.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242439,"idioma_id":4,"titulo":"Managing Web Service Interface Complexity via an OO Metric-based Early Approach [Latindex]","resumen":"Web Services have been steadily gaining maturity as their adoption in the software industry grew. Accordingly, metric suites for assessing different quality attributes of Web Service artifacts have been proposed recently ? e.g., for services interfaces in WSDL (Web Service Description Language). Like any other software artifact, WSDL documents have several inherent attributes (e.g., size or complexity) that can be measured. We present an approach to prevent a high complexity on services interfaces (WSDLs), to ease consumers to reason about services? offered functionality. Mostly, WSDLs are automatically derived from object-oriented (OO) source code, with a likely impact on complexity. Thereby, we study the statistical relationships between a recent metric suite of service interface complexity (proposed by Baski & Misra) and the well-known Chidamber & Kemerer?s OO metric suite (applied to service implementations), on a data-set of 154 real-world services. First, a theoretical validation of Baski & Misra?s suite (using Weyuker?s properties) is presented, to prove the ability to measure complexity in WSDL documents. Then, after finding high correlation between both metric suites, we have conducted a series of experiments to analyze how certain refactorings on services? source codes prior to derive WSDLs might reduce complexity. In this way, our approach exploits OO metrics as development-time indicators, to guide software developers towards obtaining less complex service interfaces.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242443,"idioma_id":5,"titulo":"De victimas a victimarios. Sobre la racionalidad mediática-penal","resumen":"En el presente trabajo nos proponemos, como objetivo general, indagar sobre las construcciones mediáticas en torno a la figura del 'individuo peligroso' en el discurso de la prensa gráfica local, tomando como caso de análisis el Diario La Capital de Rosario. Para ello, procuraremos describir un procedimiento discursivo singular en el relato mediático a raíz de los resultados de nuestro trabajo de campo: la víctima de un delito, en caso de tener antecedentes penales, será configurado como victimario. Operación discursiva que cristaliza una de las tantas manifestaciones de una racionalidad mediática-penal neo-liberal donde por una parte, se condena justificando la muerte de la víctima por pertenecer a un sector social que no merece vivir y por otro, construye la figura de una víctima que pronto será victimario de si-mismo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242444,"idioma_id":5,"titulo":"Las prosperidades restauradoras. Sobre el papel de las narrativas pentecostales en las estrategias de gobierno del sistema carcelario argentino","resumen":"El presente artículo se propone indagar sobre las narrativas construidas por eldispositivo religioso evangélico-pentecostal en contextos de encierro en relación al papel que ocupan con la configuración de tácticas de gubernamentalidad por parte del servicio penitenciario en Argentina. Para ello, son analizados el ordenamiento social que asumen los pabellones-iglesias, la división cosmológica espiritual\/mundano en la configuración de espacios y subjetividades religiosas en prisión y, asimismo, los discursos que definen a las narrativas pentecostales en el encierro en tanto que prosperidades (sanitaria, económica y penal). Tomando como casos dos cárceles de la provincia de Santa Fe, se busca, finalmente, comprender las narrativas pentecostales en los pabellonesiglesias integradas a una estrategia de gobierno que habilita la gestión de la población encarcelada, enrocándose con preceptos correccionalistas e incapacitantes cuyos efectos son la reducción de conflictividades y la definición de una cárcel que, en su cotidianidad, funcione sin novedades.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242445,"idioma_id":5,"titulo":"'Morir al orgullo'. Conformidad, insumisiones y gubernamentalidad en el dispositivo religioso evangélico pentecostal en prisión. El caso de la provincia de Santa Fe (Argentina)","resumen":"El presente artículo se propone indagar sobre los diferentes mecanismos de adaptación que ejercitan los detenidos que pertenecen al dispositivo religioso evangélico pentecostal (pabellones-iglesias) en las cárceles santafesinas. Para ello, nos preguntaremos cuáles son las diferentes formas en que emergen esas adaptaciones, cómo se articulan en clave de conformidades y su relación con las tácticas de interpelación y qué construcciones identitarias configuran. Partiendo de la hipótesis de que las adaptaciones oscilan entre una conformidad comprometida y las insumisiones carcelarias, intentaremos dar cuenta del papel que asumen los pabellones-iglesias en la configuración de tácticas de gubernamentalidad por parte del SP. Para ello, y a partir de un trabajo de campo centrado en tres Unidades Penitenciarias de dicha provincia, procuraremos dar cuenta de los procesos históricos que terminan por colocar al dispositivo religioso evangélico pentecostal como un engranaje central en el funcionamiento actual de las cárceles santafesinas, y de cómo en ese entramado se definen un conjunto de adaptaciones y resistencias que le imprimen a la dinámica carcelaria singularidades propias del funcionamiento un dispositivo como el religioso en un espacio de confinamiento con son las prisiones santafesinas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242446,"idioma_id":5,"titulo":"ESTUDIO COMPARATIVO DE SECADO DE ZAPALLO (Cucurbita moschata Duch.) VARIANDO MÉTODO Y PREPARACIÓN DE LA MUESTRA","resumen":"El objetivo del trabajo se basó en estudios de laboratorio para obtención de las curvas de secado de muestras de zapallo variedad Anco (Cucurbita moschata), evaluación y comparación de las mismas. Se analizó el comportamiento de las muestras en tres presentaciones: triturado, rallado en hebras irregulares y en trozos de forma cilíndrica, sometiendo las mismas a secado en termobalanza y en estufa mediante convección natural a 65ºC.Los tiempos de secado en todos los casos fueron similares observando la no variación del peso de la muestra, que se corresponde con una actividad de agua inferior a 0,40, lo que representa una zona segura para la conservación de las propiedades organolépticas y microbiológicas del producto. Los resultados observados mostraron un buen ajuste a los tres modelos matemáticos propuestos, Page, Midili y Parabólico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242447,"idioma_id":5,"titulo":"Representaciones, discursos y prácticas profilácticas durante la epidemia de cólera (1886-1887, Mendoza, Argentina)","resumen":"El presente artículo busca indagar en los proyectos de disciplinamiento sancionados por el Estado de la provincia de Mendoza (Argentina) durante la epidemia de cólera desarrollada en el verano de 1886 y 1887. Si bien estos planes tenían como finalidad mejorar el estado sanitario de toda la población y de la Ciudad, estos estuvieron apuntados y aplicados con mayor intensidad sobre los sectores populares y sus espacios. Esto se debió a las ideas y representaciones que en torno de la enfermedad y la muerte construyó el grupo dirigente durante estos periodos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242448,"idioma_id":5,"titulo":"CONTRIBUCIÓN AL CONOCIMIENTO DE CIANOBACTERIAS DE DOS EMBALSES DE LA PROVINCIA DE CÓRDOBA, ARGENTINA","resumen":"El presente trabajo constituye un aporte al conocimiento de las cianobacterias presentes en dos embalses de la provincia de Córdoba, San Roque y La Quebrada. Se realizaron muestreos estacionales en los embalses y desembocaduras de tributarios desde febrero de 2014 a febrero de 2016.Para la extracción de las muestras se utilizó un muestreador tipo Van Dorn y una red de plancton de 20 µm de poro. Se midieron parámetros físicos y químicos ?in situ? y las muestras fueron observadas  ?in vivo? con microscopio binocular. Se identificaron 37especies de cianobacterias, Synechococcales (15); Oscillatoriales; (12); Chroococcales (7); Spirulinales (2) y Nostocales (1).De las especies citadas  17 son nuevas  para la provincia de Córdoba de las cuales cuatro  son productoras de toxinas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242449,"idioma_id":4,"titulo":"Chemical properties of biosilica and bio-oil derived from fast pyrolysis of Melosira varians","resumen":"This study examined bio-oil and solid products generated from the diatom Melosira varians by fast pyrolysis using a fixed-bed reactor with inert gas flow and a vacuum medium. The effect of temperature (300?700 °C) on product yields, the bio-oil composition and the properties of the solid fraction were evaluated. It was found that the most suitable temperature to obtain significant amounts of high-quality bio-oil (29% yield) was 450 °C, at which point fatty acids appeared as main components. Under all operating conditions a solid material, mainly composed of siliceous frustules, was the most abundant product (59?88% yield). These materials were exhaustively characterized by SEM microscopy, Raman and FT-IR spectroscopy, XRD, elemental analysis and BET surface analyses. The structure and morphology of the biosilica were practically unaltered in the studied temperature range. The conductivity properties of the solids derived from diatom and their composites with carbon nanotubes were determined using cyclic voltammetry.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242451,"idioma_id":5,"titulo":"Aporte al conicimiento de la ficoflora del lago del Parque Sarmiento (Córdoba, Argentina)","resumen":"Los lagos urbanos son ambientes acuáticos muy valiosos para las grandes ciudades, ya que representan lugares significativos de recreación para sus habitantes y además pueden ser importantes reservorios de biodiversidad. El lago del Parque Sarmiento forma parte del patrimonio cultural y urbanístico, siendo el único ecosistema lacustre artificial de tamaño considerable de la ciudad de Córdoba. Posee un color verde intenso durante la mayor parte del año denotando la presencia de cianobacterias y algas. El objetivo de este trabajo fue conocer la ficoflora del lago, como así también sugerir técnicas de manejo empleadas en lagos similares. Los muestreos se realizaron entre 2011 y 2016. Se determinaron en total 85 taxones distribuidos en 7 grupos: Cyanobacteria (19); Rhodophyceae (1); Chloroplastida (20); Euglenozoa (8); Dinophyceae (2); Diatomea (34) y Cryptophyceae (1). El grupo con mayor número de representantes fueron las diatomeas, contribuyendo con el 41 % del total de las especies registradas. Se reveló la presencia de una especie potencialmente tóxica, Microcystis aeruginosa. Se analizan además los resultados de medidas de manejo utilizadas para el control de las macrófitas acuáticas y se plantean otras medidas de recuperación. Los datos aportados son importantes para conocer el sistema","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242455,"idioma_id":4,"titulo":"Plant tissue cultures as sources of new ene- and ketoreductase activities","resumen":"While many redox enzymes are nowadays available for synthetic applications, the toolbox of ene-reductases is still limited. Consequently, the screening for these enzymes from diverse sources in the search of new biocatalyst suitable for green chemistry approaches is needed. Among 13 plant tissue cultures, Medicago sativa and Tessaria absinthioides calli, as well as Capsicum annuum hairy roots, were selected due to their ability to hydrogenate the C[dbnd]C double bond of the model substrate 2-cyclohexene-1-one. The three axenic plant cultures showed more preference toward highly activated molecules such as nitrostyrene and maleimide rather than the classical substrates of the well-known Old Yellow Enzymes, resembling the skills of the NAD(P)H-dependent flavin-independent enzymes. When the three biocatalytic systems were applied in the reduction of chalcones, T. absinthioides showed high chemoselectivity toward the C[dbnd]C double bond whereas the other two demonstrated abilities to biohydrogenate the C[dbnd]C double bounds and the carbonyl groups in a sequential fashion.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242457,"idioma_id":5,"titulo":"Intervenciones docentes en la tarea de leer para responder cuestionarios","resumen":"Al considerar que la lectura y la escritura tienen potencialidad epistémica como instrumentos de pensamiento y desarrollo de nuevos conocimientos, este artículo focaliza la enseñanza de contenidos disciplinares con ayuda de leer y escribir en materias del nivel secundario. El objetivo principal de esta investigación fue describir y analizar las intervenciones realizadas  por tres docentes argentinos en la tarea de leer para responder cuestionarios, dicha actividad es recurrente en un curso con estudiantes de sectores socioeconómicos desfavorecidos. No se han encontrado estudios que aborden prácticas de enseñanza mediadas por la lectura y la escritura en asignaturas con población de esta procedencia. En concreto, los y las estudiantes  de esta escuela son trabajadores y madres y padres adolescentes que habitan en una villa. Bajo una metodología cualitativa, se diseñó un estudio de casos naturalista y se entrevistó en profundidad a los tres profesores y los catorce estudiantes.  Se observaron 39 clases y se recogieron documentos. Las transcripciones de las entrevistas y las observaciones de clases se analizaron  mediante estrategias de categorización y contextualización. Los resultados muestran que los profesores intervienen a través de tres funciones ?definición del medio, gestión del medio y evaluación de la tarea? que comprometen a los estudiantes en la tarea, pero que escasamente indagan por sus interpretaciones acerca de lo que están leyendo. Redefinir la estructura de esta actividad, mediante la promoción en clase de usos entramados de la lectura, la escritura y el diálogo ? como expresar las interpretaciones y debatir sobre ellas? ofrecería a los estudiantes posibilidades de acceder, comunicar y reflexionar sobre el conocimiento, al tiempo que colaboraría con el objetivo de equidad educativa.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242458,"idioma_id":5,"titulo":"Alcances de una modelización como instrumento de la ingeniería didáctica: Del género textual artículo de opinión a las secuencias didácticas en la formación de profesores de español lengua materna","resumen":"El Interaccionismo sociodiscursivo sustenta su propuesta de elaboración de secuencias didácticas para la enseñanza de lenguas en el concepto de modelo didáctico. El objetivo de este artículo es revisar teóricamente en qué consiste un modelo didáctico, su finalidad y su relación con el diseño de secuencias didácticas. Se analizan tres modelizaciones y tres secuencias, elaboradas por alumnos durante su formación docente en un profesorado en Lengua y Literatura (español L1), para dar cuenta de los alcances de dichas modelizaciones y de cómo implican decisiones sobre objetos de enseñanza y planificación del trabajo en el aula con el género textual artículo de opinión.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242459,"idioma_id":5,"titulo":"Lesiones del nervio dentario inferior en cirugías implantológicas del sector posterior mandibular","resumen":"Objetivo: Se presenta este estudio para determinarel porcentaje de alteraciones nerviosas posteriores alas cirugías implantológicas del sector posterior mandibular. Pacientes y métodos: Se realizó un estudioretrospectivo de las cirugías implantológicas del sectorposterior mandibular desde Enero de 2013 a Junio de2015. Se incluyeron sólo las cirugías de rebordes cicatrizados en brechas libres e intercalares. Resultados:Se colocaron 234 implantes en 106 pacientes en zonade premolares y molares inferiores. Se obtuvo un solocaso de alteración nerviosa post quirúrgica, determinando un porcentaje de 0,43% (IC95: 0,08% a 2,38%)por implante colocado, y un 0,94% (IC95: 0,17% a5,15%) por paciente tratado. Esta alteración nerviosarevirtió a los 2 meses. No se registraron casos de alteraciones permanentes. Conclusión: El porcentaje dealteraciones nerviosas posteriores a cirugías implantológicas difiere considerablemente en la literatura. Sehan presentado valores en un rango de 0 a 40%.Indudablementeen una buena práctica quirúrgica,como se presenta en este estudio, los valores de alteraciones nerviosas deberían ser cercanos a cero.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242460,"idioma_id":5,"titulo":"Impresión 3D para la Salud Pública","resumen":"La convergencia de nuevas tecnologías en salud permite la aplicación de disciplinas comoprocesamiento de imágenes y fabricación digital para obtener beneficios a nivelasistencial y educativo.Se conoce como fabricación digital al uso de información digital para la materialización deun modelo en tres dimensiones. Una de las tecnologías de fabricación digital másutilizadas en la actualidad se trata de la impresión 3D. Fue desarrollada originalmentepara su uso en el diseño de componentes para automóviles, aviones y computadoras. Enestas aplicaciones industriales, se utilizó la impresión 3D principalmente para evaluar lafacilidad de montaje de nuevos productos y evaluar la viabilidad de la fabricación deproductos de nuevo diseño antes de implementar la fabricación a escala industrial.La impresión 3D es una tecnología aditiva, esto quiere decir que el modelo tridimensionalse fabrica agregando el material en capas sucesivas. Esto permite utilizar solo el materialrequerido para determinado modelo, evitando la generación de desperdicios. Medianteimpresión 3D se pueden obtener piezas impresas en material plástico (ABS o PLA),plástico flexible, basado en polvo y metálicos. Dentro de las tecnologías de impresión 3Ddisponibles podemos encontrar las siguientes: fdm, estereolitografía, polvo, polyjet,sinterizado laser, bioimpresión.Con las capacidades ofrecidas por las tecnologías de obtención de imágenes médicasactuales, como la tomografía por rayos X, tomografía por resonancia magnética (MRI) y laecografía 3D, el uso de la impresión 3D ha iniciado una expansión en aplicacionesmédicas. Mediante la utilización de software libre (InVesalius, 3DSlicer, etc.) o propietario(MIMICS, Osirix, etc.) se pueden obtener los modelos a partir de imágenes en formatoDICOM u otro. Luego de un proceso de tratamiento de imágenes conocido comosegmentación, es posible obtener el biomodelo a imprimir en extensión STL o similar.Los biomodelos impresos pueden ser aplicados en las siguientes áreas: neurocirugía,cardiología, traumatología y cirugía maxilofacial, entre otras. Dentro de las aplicacionesasistenciales se encuentra la obtención de biomodelos para comunicación entreprofesionales y planificación quirúrgica. A su vez, es posible la obtención de guíasquirúrgicas. Dichas guías permiten la aplicación de la planificación quirúrgica virtual de unprocedimiento quirúrgico y también un abordaje mínimamente invasivo. Con respecto alas aplicaciones para enseñanza, se pueden generar biomodelos de órganos normales ypatológicos para ser usados por docentes y alumnos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242461,"idioma_id":4,"titulo":"Cavitary Pulmonary Sporotrichosis: Case Report  and Literature Review","resumen":"A case of cavitary pulmonary sporotrichosis without mucocutaneous involvement caused by Sporothrix schenckii is reported in a sexagenarian woman with a long smoking history. The patient was hospitalized for septic shock with multiorgan failure from a respiratory focus. The diagnosis was delayed due to the fungal etiological agent was not initially considered in the differential diagnosis. A good clinical and radiological evolution was obtained with the antifungal therapy. Occasional cases of primary pulmonary sporotrichosis have been reported in the literature. Due to its low incidence, this is a less-known and underestimated clinical form. Both clinical suspicion and microbiological studies are needed to reach pulmonary sporotrichosis diagnosis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242462,"idioma_id":5,"titulo":"La importancia de los géneros en la Didáctica de las Lenguas. Una experiencia pedagógica en Inglés Técnico en la Educación Superior","resumen":"Este artículo analiza unapropuesta didáctica de Inglés Técnico en la Educación Superior implementadadurante el año 2015 y 2016 en la Licenciatura en Agroecología de la UniversidadNacional de Río Negro, (El Bolsón, Argentina). La propuesta fue diseñada teniendocomo fundamentos teóricos la didáctica de Inglés para Fines Específicos y losaportes de la Dra. Paula Carlino acerca de la lecto-escritura en la EducaciónSuperior, enfatizando la enseñanza del lenguaje en uso en situacionesrelevantes para el estudiante. Se revisa dicha propuesta a la luz de lasconcepciones del lenguaje propuestas por Riestra, en línea con Voloshinov y Bronckart.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242463,"idioma_id":5,"titulo":"¿CÓMO LOGRAR UN MUNDO DONDE QUEPAN TODOS LOS MUNDOS? ANÁLISIS DE LA CONTROVERSIA AMBIENTAL DEL CERRO PERITO MORENO, RÍO NEGRO, ARGENTINA (2010-2013)","resumen":"En este artículo se profundizan algunos de los resultados de la tesis ¿?Sin loteo no hay esquí'o ?Sí al esquí, no al loteo?? Análisis de la controversia ambiental del cerro Perito Moreno, El Bolsón, Río Negro (2010-2013). En dicha tesis se investigaron las representaciones y prácticas de las partes involucradas, tanto en la construcción de la controversia como en su proceso de cambio, por medio del análisis de documentos (expediente, medios de prensa, informes técnicos de las empresas y organismos gubernamentales) y entrevistas en profundidad a informantes claves. Se tomó una postura constructivista, adoptando el paradigma cualitativo y la estrategia del estudio de casos. Se ahondaron en las características particulares de las controversias ambientales en Latinoamérica (diferencias culturales, sistemas institucionales y políticas ambientales débiles y la dificultad de sentar a los actores principales en una mesa de negociación) para observar los desafíos relacionados con la posibilidad de lograr un debate participativo. Se analizaron las diferencias culturales presentes en las partes involucradas en la controversia y los factores que pudieron originarlas. Asimismo, se estudiaron las prácticas elegidas por las partes para llevar a cabo sus objetivos. En el caso estudiado se pudo ver la productividad jurídica, territorial e institucional de esta controversia, a pesar de que las partes no han llegado a participar en un debate formal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242464,"idioma_id":5,"titulo":"Las Bases de Alberdi y las culturas de las libertades","resumen":"Se analizan las Bases de Alberdi utilizando el marco conceptual diseñado por Maurizio Fioravanti acerca de las posibles fundamentaciones teóricas de las libertades. El punto de partida de su propuesta lo conforma la propia identificación y definición de la 'cultura de las libertades', entendida como 'la cultura que en su conjunto inspira su sistematización en sentido jurídico-positivo' teniendo en cuenta que 'cada tiempo histórico produce su propia cultura de las libertades'. Así, la aproximación al problema de las libertades puede ser de tipo historicista,individualista o estatalista. Fioravanti asevera que, en realidad, no se presentan en forma pura, sino que tienden a combinarse, pero esta combinación sólo se forja entre dos de los modelos excluyendo al tercero.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242468,"idioma_id":5,"titulo":"Implantes Peek de última generación","resumen":"El Peek, Polieter cetona es un termoplástico de doble fase que desde los años 90 se ha abierto paso entre los biomateriales como candidato para el reemplazo de implantes con componentes metálicos...","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242469,"idioma_id":5,"titulo":"Principales modificaciones al Código Fiscal de Mendoza Ley impositiva 2017","resumen":".","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242470,"idioma_id":5,"titulo":"El agua en el constitucionalismo provincial argentino: distintas perspectivas","resumen":".","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242471,"idioma_id":5,"titulo":"Discriminación, cupo femenino y reparación del daño colectivo","resumen":".","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242472,"idioma_id":5,"titulo":"Diálogo jurisprudencial y valor del precedente. Desafío de los superiores tribunales de justicia en el federalismo argentino","resumen":".","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242474,"idioma_id":5,"titulo":"Acto, gesto y acting out, a propósito del hombre del magnetófono","resumen":"El artículo analiza el caso del paciente conocido como 'el hombre del magnetófono', tomando en cuenta la disputa entre Sartre y Pontalis respecto de la publicación del testimonio en Les Temps Modernes. Se toman en cuenta las categorías de acting out, acto y gesto, desde las perspectivas teóricas sartreana y lacaniana, con el objetivo de vislumbrar a qué corresponde semejante irrupción del paciente en el consultorio de su ex-analista.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242478,"idioma_id":4,"titulo":"Spectral-like duality for distributive Hilbert algebras with in\fmum","resumen":"Abstract. Distributive Hilbert algebras with infimum, or DH^{wedge}-algebras for short, are algebras with implication and conjunction, in which the implication and the conjunction do not necessarily satisfy the residuation law. These algebras do not fall under the scope of the usual duality theory for lattice expansions, precisely because they lack residuation. We propose a new approach, that consists of regarding the conjunction as the additional operation on the underlying implicative structure. In this paper we introduce a class of spaces, based on compactly-based sober topological spaces. We prove that the category of these spaces and certain relations is dually equivalent to the category of DH^{wedge}-algebras and wedge-semi-homomorphisms. We show that the restriction of this duality to a wide subcategory of spaces gives us a duality for the category of DH^{wedge}-algebras and algebraic homomorphisms. This last duality generalizes the one presented in [7] for implicative semilattices. Moreover, we use the duality to give a dual characterization of the main classes of filters for DH^{wedge}-algebras, namely, (irreducible) meet filters, (irreducible) implicative filters and absorbent filters.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242479,"idioma_id":5,"titulo":"CONSTRUCCIÓN SOCIAL DE REDES EN EL ACOMPAÑAMIENTO PARA PRODUCTORES- ARTESANOS EN SALTA, PROYECTO ADUJA","resumen":"La Feria Balcarce está ubicada estratégicamente al pie de la vieja estación de trenes en la ciudad de Salta, donde convergen productores artesanales urbanos y tradicionales, habitantes de la ciudad de salta y sus alrededores, constituyendo a este espacio como una de las principales ofertas productivas artesanales en la ciudad. El espacio que la alberga convive con distintas actividades y prácticas sociales, que fueron reconfigurando la zona y principalmente la calle Balcarce a esa altura, convirtiéndose actualmente en un importante referente espacial con la resignificación de la zona.Este trabajo presenta el proyecto Aduja desarrollado durante el año 2014-2015 y las acciones de intercambio y co-construcción tecnológica desarrolladas. Los diagnósticos y avances de intercambios producidos en el inicio del proyecto como tesina de grado hasta las primeras acciones de investigación y transferencia en el primer año permitieron observar, entre otras cosas, la falta de reconocimiento de sus artesanos por parte de las instituciones estatales locales y la sociedad civil. Como también la dificultad, tanto institucional como de la propia organización, para la apropiación y puesta en valor de la artesanía urbana local que producen.Sobre estos emergentes se accionó a fin de elaborar estrategias y herramientas que colaboren en el proceso de superación de la situación socio-productiva mencionada, a partir de fortalecer la percepción de calidad de la oferta cultural de la feria y sus redes institucionales. Como resultado de este proceso se constituyeron productos materiales y gestiones como: Guía de conceptos teóricos para el trabajo artesanal; Técnicas para la materialización de productos artesanales; Semielaborado en cuero; Presentación de productos y Empaques; Concurso interno ?Raíces?.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242480,"idioma_id":5,"titulo":"El diseño social contemporáneo en Argentina. Una mirada sobre su relación contextual","resumen":"Diseño social y su devenir El diseño o, según la expresión que preferimos,los diseños  se encuentran en el seno de las disciplinas que producen y\/o reproducen prácticas sociales (Doberti, 2014). Al acordar con este criterio categorial, el enunciado diseño social resultaría, en un sentido amplio, cuasi redundante pues sin el componente social no parece haber una praxis disciplinar posible. No obstante, el uso de dicho concepto con un sentido específico propone tipificar determinadas acciones que insisten desde hace cierto tiempo, en el campo de lo proyectual en un posicionamiento crítico respecto a los formatos canónicos de las disciplinas, autoidentificándose entre otros como ?diseño social?, para nosotros 'diseños sociales', bajo la perspectiva de informar, desde el nombre, acerca de su pluralidad y dar cuenta de sus diferencias, más allá de los aspectos que, en efecto, comparten.Los ?diseños sociales? se constituyen en la actualidad como una categoría en proceso de determinación, como menciona Ledesma (2013:98) se trata aún ?de un área de escasa precisión conceptual?; el corpus que cabría inscribir en ella parece relacionarse con acciones tales como diseño para el desarrollo, para la inclusión y\/o accesibilidad, diseño y cadenas de valor, sostenible, eco-diseño, socialmente responsable, universal, centrado en el usuario, slow, para adultos mayores, para todos, libre de barreras, transgeneracional, participativo, diseño sin edad, entre otras. Todas ellas, proponen críticas a la práctica disciplinar exponiendo discontinuidades respecto a los territorios contemporáneos, desde miradas con perspectivas evolucionistas a proposiciones de ruptura.En este artículo haremos un recorrido por algunas de las consideraciones vinculadas en términos históricos y contemporáneos con el diseño en su campo, función o componente social. Trataremos de señalar en forma de hipótesis, algunos momentos claves en este proceso de conformación y demarcaremos lo que a nuestro entender los diferencian en términos estructurales. Esperamos poder aportar al esfuerzo de colectivos latinoamericanos, por darle forma en términos de prácticas, procesos de reflexión y acción política, al área de los diseños sociales, con el fin de profundizar su capacidad de acompañar el desarrollo de su sociedad de pertenencia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242481,"idioma_id":5,"titulo":"Tecnologías y hábitat inclusivas\/o Diseño participativo y fortalecimiento socio-productivo en unidades Feriales como estrategia de hibridación de bordes. El caso de la Feria de Economía Social y Solidaria del Municipio de Quilmes.","resumen":"Este escrito  analiza una experiencia proyectual, en el marco de Políticas Públicas de fortalecimiento socio laboral para el hábitat popular que fueron desarrolladas en convenio entre la Universidad de Buenos Aires (FADU), la Universidad Nacional de Quilmes a través de la Secretaría de Extensión Universitaria, en particular el  Programa Universitario de Incubación Social y el Municipio de Quilmes This paper tries to describe and analyze a project experience, within the framework of socio-labor strengthening policies for the habitat that were developed in agreement between the Universidad de Buenos Aires (FADU), the Universidad Nacional de Quilmes, Programa Universitario de Incubación Social and the municipality of this same locality.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242482,"idioma_id":4,"titulo":"The effects of Cissampelos pareira extract on envenomation induced by Bothropsdiporus snake venom","resumen":"Ethnopharmacological relevance: Ophidian accidents are a serious public health problem in Argentina; the Bothrops species is responsible for 97% of these accidents, and in particular, B. diporus is responsible for 80% of them. In the northeast of the country (Corrientes Provinces), Cissampelos pareira L. (Menispermaceae) is commonly used against the venom of B. diporus; its use is described in almost all ethnobotanical literature from countries where the plant grows. Aim of the study: In this study, the in vitro and in vivo antivenom activities of C. pareira extracts were evaluated against B. diporus venom, with a particular focus on the local e&#64256;ects associated with envenoming. The seasonal in&#64258;uence on the chemical composition of the active extracts was also studied, in order determine the associated range of variability and its in&#64258;uence on the antivenom activity. Materialsandmethods: Thisresearchwasconductedusingaerialparts(leaves, &#64258;owers,tenderstems)androotsof Cissampelos pareira collected from two di&#64256;erent phytogeographic regions of Corrientes (Argentina); Paso de la Patria and Lomas de Vallejos. In addition, to perform a seasonal analysis and to evaluate the metabolic stability, material was collected at three di&#64256;erent growth stages. In vivo and in vitro anti-snake venom activities were tested, and a bio-guided chromatographic separation was performed in order to determine the active chemicals involved. The fractions obtained were analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and the chemical pro&#64257;le of the most active constituent was analyzed by ultra high-performance liquid chromatography coupled to quadrupole\/high-resolution mass spectrometry (Q-Orbitrap). (UHPLC-MS). Results: ThealcoholicextractwasfoundtobethemostactiveThebio-guidedfractionationallowedselectionone fraction to be analyzed by UHPLC-MS in order to identify the components responsible for the activities found; this identi&#64257;ed &#64257;ve possible &#64258;avonoids. Conclusions: Our studies of the activity of C. pareira against the venom of B. diporus have con&#64257;rmed that this species possesses inhibitory e&#64256;ects in both in vitro and in vivo models. Moreover, the present data demonstrate that certain &#64258;avonoids may mitigate some of the venom-induced local tissue damage.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242483,"idioma_id":4,"titulo":"Vortex dynamics in &#946;-FeSe single crystals: effects of  proton irradiation and small inhomogeneous stress","resumen":"We report on the critical current density Jc and the vortex dynamics of pristine and 3 MeV proton irradiated (cumulative dose equal to 2×1016cm&#8722;2 ) &#946;-FeSe single crystals. We also analyze a remarkable dependence of the superconducting critical temperature Tc, Jc and the flux creep rate S on the sample mounting method. Free-standing crystals present Tc=8.4(1)K, which increases to 10.5(1)K when they are fixed to the sample holder by embedding them with GE-7031 varnish. On the other hand, the irradiation has a marginal effect on Tc. The pinning scenario can be ascribed to twin boundaries and randompoint defects. We find that the main effect of irradiation is to increase the density of random point defects, while the embedding mainly reduces the density of twin boundaries. Pristine and irradiated crystals present two outstanding features in the temperature dependence of the flux creep rate: S(T) presents large values at low temperatures, which can be attributed to small pinning energies, and a plateau at intermediate temperatures, which can be associated with glassy relaxation. From Maley analysis, we observe that the characteristic glassy exponent µ changes from &#8764; 1.7 to 1.35-1.4 after proton irradiation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242489,"idioma_id":5,"titulo":"Que la universidad se vista de feminismos para enfrentar las violencias sexistas","resumen":"No suena novedoso plantear que las violencias machistas ?golpean? duramente al conjunto de las mujeres de todaslas clases en todos los ámbitos sociales. Hace décadas que el movimiento de mujeres y feminista viene intentandocolocar en agenda la cuestión de la violencia de género y contra las mujeres, sin obtener mucho éxito en el intento.Sin   embargo,   los   últimos   dos   años   en   nuestro   país   ?en   un   proceso   que   fue   extendiéndose   inclusivecontinentalmente? estuvieron marcados por las movilizaciones masivas, la visibilización de las persistentes luchasy una gran sensibilización social contra las violencias sexistas. Las multitudinarias marchas de #NiUnaMenos delos días 3 de junio de 2015, 2016 y 2017, la inmensa convocatoria del  31º Encuentro Nacional de Mujeres,celebrado en la ciudad de Rosario, y el paro de mujeres del 19 de octubre de ese mismo año, así como el ParoInternacional de Mujeres del 8 de marzo (#8M) de este año, muestran la urgencia, la irreverencia y la creatividadque asume la demanda para acabar con este fenómeno que no cesa de crecer y recrudecerse.En ese marco, docentes, estudiantes y graduadas feministas en distintas Universidades Nacionales (en adelante,UUNN) del país hemos abierto instancias de debate que han conducido, en muchas ocasiones, a la creación denuevos marcos regulatorios con el objetivo de desnaturalizar los mecanismos que producen prácticas misóginas ymachistas, prevenirlas, sancionarlas, así como reparar los daños que tales violencias provocan en las personas quelas sufren","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242491,"idioma_id":5,"titulo":"FEMINISMOS Y CIENCIAS SOCIALES. PROPUESTAS PEDAGÓGICAS Y APORTES CRÍTICOS PARA REVISAR PROGRAMAS DE FORMACIÓN EN EL GRADO","resumen":"En este trabajo presentamos los avances producidos en el marco del proyecto de investigación Feminismo y Ciencias Sociales: procedencias, inserciones y carencias en el diseño curricular, que tiene el propósito de problematizar los enfoques teórico-epistemológicos predominantes en las propuestas académicas de formación en ciencias sociales. Como parte de las tareas de investigación propusimos revisar los programas de asignaturas correspondientes a las licenciaturas en Ciencia Política, Comunicación Social, Relaciones Internacionales y Trabajo Social que se imparten en la Facultad de Ciencia Política y Relaciones Internacionales (RR. II.) de la Universidad Nacional de Rosario (UNR). Esta se tradujo en una propuesta pedagógica desarrollada junto lxs estudiantes que cursan la unidad electiva Introducción a la Perspectiva de Género en la misma Facultad. Aquí reflexionamos sobre los resultados de este ejercicio investigativo revisando las categorías hegemónicas que están presentes en los programas elaborados para la formación de profesionales cuyos perfiles se orientan a investigar, planificar, intervenir en diversos ámbitos y situaciones sociales, y nos preguntamos por las ausencias que imposibilitan reconocer los condicionamientos estructurales de un sistema patriarcal y heterosexista dónde el género y la sexualidad constituyen, junto con las posiciones de clase, étnicas-raciales, nacionales y generacionales, marcas que determinan las coordenadas de lxs sujetxs (ver nota 2) en las asimétricas relaciones de poder.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242493,"idioma_id":4,"titulo":"First experimental release of the red-and-green macaw Ara chloropterus in Corrientes, Argentina","resumen":"In 2015 seven captive-bred red-and-green macaws Ara chloropterus were experimentally released into the Iberá National Park, Corrientes, Argentina. After a month in a pre-release cage, they were hard released. Two birds were preyed upon, three flew beyond our detection range, one transmitter was recovered underwater, and one bird was recaptured. We identify ways in which future releases of captive-bred macaws could be improved.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242494,"idioma_id":5,"titulo":"Polidactilia y asimetria  fuctuante en el Loro hablador (Amazona aestiva): ¿signos de estres del desarrollo?","resumen":"Some abnormalities such as polydactyly and  uctuating asymmetry occur as a result of developmental stress. A case of developmental stress that includes poly- dactyly,  uctuating asymmetry, and fault bars in one Blue-fronted Amazon nestling (Ama- zona aestiva), is reported. These anomalies were related to the stress caused by a wildland  re. Two nestlings of a same nest were examined. Physical examination showed anomalies only in the small nestling which included a) polydactyly in the right leg, b) colour asymmetry in wing feathers with an atypical staining pattern in the right wing and c) stress bars in red pigmentation area of secondary feathers of both wings. Wildland  res should be considered as a major stress factor for nesting birds of the Beni Savanna (north of Bolivia).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242496,"idioma_id":4,"titulo":"Site-occupancy modelling: A new approach to assess sensitivity of indicator species","resumen":"One of the most challenging aspects of quality indices has been to compile reliable measures of the species?sensitivity to various magnitudes and different kinds of ecosystem attributes. Occupancy modelling has becomeincreasingly useful to ecologists because provides a flexible framework to estimate the habitat use as a functionof site information. We modelled occupancy of oligochaete species from physicochemical variables of Pampeanstreams; and we described the change in occupancy along the gradient of each explanatory physicochemicalvariable. We proposed three phases (resistance, tolerance and extinction) to describe the sensitivity of the speciesin terms of occupancy. Seventeen of the 33 taxa of oligochaetes were enough abundant to be modeled. In eightspecies, we obtained a total of 11 different models including physicochemical covariates. Occupancy wasexplained by conductivity in four species, by dissolved oxygen in three species, and by nutrients in four species.The analysis of phases (resistance, tolerance and extinction) to describe the sensitivity of the species in terms ofoccupancy, offers a new methodology to understand how the species behave along a stressor gradient. Detaileddescriptions of sensitivity of these local species, will helps ecologists to generate more accurate biotic indices.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242497,"idioma_id":4,"titulo":"Beneficial roleof the phytoestrogen Genistein on vascular calcification","resumen":"Although soy phytoestrogen (PE) are proposed to prevent or improve postmenopausal vascular and bone diseases, the currently available data are controversial and unclear. In this study we evaluated the molecular and biochemical action of Genistein (Gen) on the cellular events involved in vascular calcification. Rat monocytes, aortic vascular cell and osteoblasts cultures in vitro exposed to Gen were employed. Gen down regulated the expression of cell adhesion molecules involved in stable leukocyte attachment. Using flow cytometry we found that the PE significantly diminished monocyte integrins CD11b, CD11c and CD18 expression either under basal and pro-inflammatory environment. At endothelial level, Gen also reduced ICAM-1 mRNA expression. On vascular muscle cells, the PE markedly reduced cell proliferation and migration. When vascular calcification was studied, muscle cells transdifferentiation into osteoblasts like cells was evaluated. Cells were cultured in osteogenic medium for 21 days. The expression alkaline phosphatase (ALP), and the presence of calcified nodules in the extracellular matrix were selected as features of muscle transdifferentiation. Calcified muscle cells exhibited higher levels of ALP activity (osteoblastic marker) and enhanced deposition of calcium nodules respect to native cells. Both markers were significantly reduced after Gen treatment. In contrast to this anti-osteogenic action, on bone cells Gen promoted osteoblasts growth, enhanced ALP activity and increased matrix mineralization. Its mitogenic action on osteoblasts depends directly on nitric oxide endothelial production stimulated by the PE. The data presented suppose a beneficial role of Gen on bone and vascular cells, with a cross link between both systems.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242498,"idioma_id":4,"titulo":"A management strategy for the long-term conservation of the Endangered sand-dune lizard Liolaemus multimaculatus in the Pampean coastal dunes of Argentina","resumen":"The sand-dune lizard Liolaemus multimaculatus is an Endangered species endemic to the Pampean coastal dunes of Argentina. To inform the development of a future Action Plan for this species, we investigated the demography and conservation status of all remaining populations, and we suggest management actions appropriate to local needs. We used population viability analysis to assess extinction risk in three inbreeding scenarios and estimate the minimum viable population and the minimum area requirement. To assess the current status of each local population, we used information related to population size, human pressure and connectivity. The results were then used to set and prioritize conservation management actions at local level. Our models indicated that populations of 2,400 individuals would be viable in the long term and that inbreeding depression has a strong effect on extinction risk. The southern patches of coastal dune contain the largest populations of sand-dune lizards, and they are also better connected and less threatened. We suggest land protection as the priority management action for populations larger than the minimum viable population, whereas habitat recovery, when possible, should be the priority for patches of coastal dune smaller than the minimum area requirement. Supplementation with a small number of individuals could stabilize unviable populations but should be considered only in certain situations. The long-term conservation of the sand-dune lizard will be feasible only if a conservation action plan is developed and implemented.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242499,"idioma_id":4,"titulo":"Current threats faced by Neotropical parrot populations","resumen":"Psittaciformes (parrots, cockatoos) are among the most endangered birds, with 31% of Neotropical species under threat. The drivers of this situation appear to be manifold and mainly of anthropogenic origin. However, this assessment is based on the last extensive consultation about the conservation situation of parrots carried out in the 1990s. Given the rapid development of anthropogenic threats, updated data are needed to strategize conservation actions. Using a population approach, we addressed this need through a wide-ranging consultation involving biologists, wildlife managers, government agencies and non-governmental conservation organizations. We gathered up-to-date information on threats affecting 192 populations of 96 Neotropical parrot species across 21 countries. Moreover, we investigated associations among current threats and population trends. Many populations were affected by multiple threats. Agriculture, Capture for the Pet Trade, Logging, each of them affected > 55% of the populations, suggesting a higher degree of risk than previously thought. In contrast to previous studies at the species level, our study showed that the threat most closely associated with decreasing population trends is now Capture for the local Pet Trade. Other threats associated with decreasing populations include Small-holder Farming, Rural Population Pressure, Nest Destruction by Poachers, Agro-industry Grazing, Small-holder Grazing, and Capture for the international Pet Trade. Conservation actions have been implemented on < 20% of populations. Our results highlight the importance of a population-level approach in revealing the extent of threats to wild populations. It is critical to increase the scope of conservation actions to reduce the capture of wild parrots for pets.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242500,"idioma_id":4,"titulo":"Reproductive parameters of the Turquoise-fronted Parrot (Amazona aestiva) in the dry Chaco forest","resumen":"The progressive exploitation and destruction of nesting habitat in recent years, combined with the substantial pressure from legal and illegal removal of wild nestlings and adults, justifies the development of a comprehensive study on the reproductive biology of the Turquoise-fronted Parrot (Amazona aestiva). We analyzed breeding parameters in a wild protected population of Turquoise-fronted Parrots in the Chaco forest, Argentina, examining variation among years, over the course of the breeding season, and in relation to the age of the nest. Mean clutch-size per nesting attempt was 3.68 eggs. Hatching success (proportion of eggs laid that hatch) was 0.73. Fledging success (proportion of nestlings that fledge) was 0.88. The overall breeding success (mean number of fledglings per laying female per year) was 0.95. Clutch size did not vary among years but it decreased with the delay of the nest initiation date. Hatching failure was the greatest cause of egg partial losses, and brood reduction was the main cause of nestling partial loses. Brood reduction was positively correlated with clutch size and with egg-laying date. We did not find interannual variation in any of the clutch or brood size variables. Our results showed that the population of Turquoise-fronted Parrots in the dry Chaco forest has high values of clutch size and nestling survival, and low values of hatching success. However, some aspects of the breeding biology need more attention, especially if the species continues to be harvested.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242501,"idioma_id":5,"titulo":"Resistencias femeninas. Arte contemporáneo regional desde una perspectiva de género.","resumen":"El presente artículo explora la capacidad de la teoría de género para abordar la producción artística de mujeres de la ciudad de Resistencia (Chaco, Argentina) con el objetivo de analizar sus trabajos a partir de nociones, conceptos y problemáticas que han podido leerse en sus obras. La selección corresponde a producciones de tres autoras que viven y trabajan actualmente en Resistencia y que han planteado a través de sus obras la sexualidad femenina como temática para la problematización de ideas por medio de su compromiso estético y personal. Con el fin de reflexionar sobre la creación estética a partir del tópico de la\/s sexualidad\/es en diferentes expresiones plásticas, la descripción iconográfica, el análisis de las obras y la lectura en clave de género confluyen en este trabajo para poner en cuestión categorías y conceptos abordados en las obras como el trabajo doméstico, los estereotipos de mujeres, la maternidad, ciertos tabúes que persisten en la cultura, modos de violencia, el deseo y el goce sexual femenino.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242504,"idioma_id":5,"titulo":"Repetir Curso: Condicionantes del nivel primario usando datos de panel georreferenciados","resumen":"Utilizando un panel de datos de 220 escuelas primarias con información georreferenciada, este trabajo explora los determinantes de la tasa de repetición a nivel escuela, contexto y vecindario geográfico. Los resultados muestran que a nivel escuela únicamente la matrícula escolar es una variable significativa. Los factores contextuales como la tasa de desempleo y la proporción de mujeres en edad escolar se relacionan con la tasa de repetición primaria. Además, el desempleo y la proporción de mujeres de las áreas contiguas muestran efectos significativos. Estos resultados reflejan la importancia de incorporar la localización de las escuelas y su entorno social a la hora de establecer adecuadas políticas educativas que contemplen a la  repetición escolar.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242506,"idioma_id":4,"titulo":"Collecting Evidence to Inform Salt Reduction Policies in Argentina: Identifying Sources of Sodium Intake in Adults from a Population-Based Sample","resumen":"The maximum content of sodium in selected processed foods (PF) in Argentina was limited by a law enacted in 2013. Data about intake of these and other foods are necessary for policy planning, implementation, evaluation, and monitoring. We examined data from the CESCAS I population-based cohort study to assess the main dietary sources among PF and frequency of discretionary salt use by sex, age, and education attainment, before full implementation of the regulations in 2015. We used a validated 34-item FFQ (Food Frequency Questionnaire) to assess PF intake and discretional salt use. Among 2127 adults in two Argentinean cities, aged 35?76 years, mean salt intake from selected PFs was 4.7 g\/day, higher among male and low education subgroups. Categories of foods with regulated maximum limits provided near half of the sodium intake from PFs. Use of salt (always\/often) at the table and during cooking was reported by 9% and 73% of the population, respectively, with higher proportions among young people. Reducing salt consumption to the target of 5 g\/day may require adjustments to the current regulation (reducing targets, including other food categories), as well as reinforcing strategies such as education campaigns, labeling, and voluntary agreement with bakeries.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242509,"idioma_id":4,"titulo":"Biological and environmental effects on fine scale seed dispersal of an invasive tree in a secondary subtropical forest","resumen":"Dispersal abilities of invading species emerge from the interaction between the species and some features of the target community. Ligustrum lucidum is a tree species invading different ecosystems. Major spatial patterns of Ligustrum invasions and their ecological consequences have been analyzed, but no study addressed the dispersal process at a fine scale, assessing the effects of different biological and environmental factors. Ligustrum lucidum is an ornithochoric species. The structure of the environment determines bird movements and thus affects seed dispersal. We used inverse modeling to analyze bird-mediated dispersal of L. lucidum seeds in a secondary Yungas forest and surrounding crop-fields. We assessed the effects of egestion mode (regurgitation and defecation) and tree density (as an environment character) on seed dispersal. Seed dispersal presented different spatial patterns depending on the egestion mode. Tree density was positively associated with the number of regurgitated dispersed seeds and negatively associated with the number of defecated dispersed seeds. In both cases, dispersal distance increased in open areas, but absence of perches inhibited seed arrival. Thus, spread of L. lucidum is facilitated in open areas with some trees; inside the native forest, short distance dispersal facilitates the gradual invasion by this exotic species. Our results suggest that processes like crop abandonment and forest succession, which are active in subtropical montane systems, may facilitate L. lucidum invasion. Our seed dispersal models should be combined with actual distribution maps of L. lucidum to identify areas vulnerable to new invasions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242510,"idioma_id":5,"titulo":"Evaluación del estado de Salud Bucal de niños de 4 y 5 años que asisten al Centro de Desarrollo Infantil Mitai Roga N° V, de la ciudad de Corrientes Capital","resumen":"La caries en la infancia temprana es una forma particularmente virulenta de caries que afecta a los niños más pequeños y que puede causar grandes estragos en la dentición de los infantes en un periodo particularmente corto. Se realizó un estudio descriptivo, longitudinal en  niños entre 4 y 5 años de ambos sexos, que asistieron al Centro de Desarrollo Infantil Mitai Roga N° V de la ciudad de Corrientes durante el año 2016. El objetivo fue evaluar el estado de Salud Bucal en niños de 4 y 5 años que asistieron al Centro de Desarrollo Infantil Mitai Roga N° V. Se realizaron registros en la Historia Médica-Dental, examen clínico, previo consentimiento Informado. Posteriormente se llevó a cabo el Programa ?Por una sonrisa sana y feliz.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242511,"idioma_id":5,"titulo":"EPIDEMIOLOGIA DE LA CARIES DENTAL EN NIÑOS DE 3-5 AÑOS DEL  JARDÍN DE INFANTES PINOCHO","resumen":"Uno de los principales problemas de la salud pública, a nivel mundial son las enfermedades bucodentales. La caries dental es la enfermedad que padece aproximadamente 90% de la población en América Latina. Se realizó un estudio descriptivo, longitudinal en niños entre 3 a 5 años, que asistieron al Jardín de Infantes Pinocho de la ciudad de Corrientes. Se realizaron registros en la Historia Médica-Dental, examen clínico, previo consentimiento Informado. El indicador epidemiológico utilizado fue el ceod. Posteriormente se llevó a cabo el desarrollo del Programa ?Por una sonrisa sana y feliz. Los registros obtenidos reflejan que el 64% de los niños presentan caries, por lo cual es necesario la implementación de programas de promoción y prevención de la salud bucal, la modificación de hábitos de vida para mantener y preservar la salud, teniendo en cuenta que son niños con escasas posibilidades de atención odontológica privada.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242512,"idioma_id":4,"titulo":"Systematics of the Culex coronator complex (Diptera: Culicidae): morphological and molecular assessment","resumen":"The Culex coronator complex of the mosquito subgenus Culex includes five currently recognized species: Cx. camposi,Cx. coronator, Cx. ousqua, Cx. usquatissimus and Cx. usquatus. Because of the confusing taxonomic history of thecomplex, we aimed to clarify the specific status of these nominal forms based on an examination of holotypes andlectotypes and molecular data from other specimens. Critical assessment of published descriptions and study of typespecimens revealed that the known distributions of the five species overlap considerably and exhibit biotic sympatryin some areas. Sequences from the COI barcode region and complete mitochondrial genomes were used to assess therelationships and degree of genetic divergence of the species and two newly discovered morphological forms, Cx. coronatorForms1 and 2.Geneticdistances in the COIdataset varied from 0.00 to 2.67%,with the largest relative divergencebeing4.41 between specimens of Cx.coronatorand Cx.coronatorForm1.BayesianPoissontree process analysis of theCOIbarcode region also failed to provide support for the nominal species.Evidence from the morphological and moleculardata thus leads us to conclude(at least provisionally) that the Cx.coronatorcomplex is a single polymorphic species.Theforms constitute a monophyletic group but there is no support for the specific status of the five nominal forms.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242513,"idioma_id":5,"titulo":"Efectividad antimicrobiana del extracto etanólico de propóleos frente a Estreptococos mutans","resumen":"El propóleos es una sustancia natural que posee una amplia variedad de propiedades vinculadas a las ciencias de la salud, aporta una alternativa para nuevos tratamientos en odontología así como también para la prevención de caries. De acuerdo al lugar de origen, condiciones climatológicas y tipo de especies botánicas circundantes, son las características que va a reunir. Por ello la particularidad de conocer el tipo de propóleos de nuestra zona geográfica y las propiedades que posee de acuerdo a sus compuestos químicos. El objetivo de este trabajo fue determinar el efecto antimicrobiano del propóleos sobre los Estreptococos mutans. Se realizó un estudio experimental, in vitro. Se prepararon las soluciones de propóleos al 2,5%, 5 % y 10%. Se realizaron placas de agar Mitis Salivarius para los Estreptococos mutans, se aplicaron en las placas los discos de papel, posteriormente se midieron los halos de inhibición formados. La concentración de propóleos al 10% demostró que produce mayor efecto en la inhibición del crecimiento bacteriano de Streptococcus mutans.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242517,"idioma_id":4,"titulo":"Variation in the Distribution of Putative Virulence and Colonization Factors in Shiga Toxin-Producing Escherichia coli Isolated from Different Categories of Cattle","resumen":"Shiga toxin-producing Escherichia coli (STEC) are pathogens of significant public health concern. Several studies have confirmed that cattle are the main reservoir of STEC in Argentina and other countries. Although Shiga toxins represent the primary virulence factors of STEC, the adherence and colonization of the gut are also important in the pathogenesis of the bacteria. The aim of this study was to analyze and to compare the presence of putative virulence factors codified in plasmid -katP, espP, subA, stcE- and adhesins involved in colonization of cattle -efa1, iha- in 255 native STEC strains isolated from different categories of cattle from different production systems. The most prevalent gene in all strains was espP, and the less prevalent was stcE. katP was highly detected in strains isolated from young and rearing calves (33.3%), while subA was predominant in those isolated from adults (71.21%). Strains from young calves showed the highest percentage of efa1 (72.46%), while iha showed a high distribution in strains from rearing calves and adults (87.04 and 98.48% respectively). It was observed that espP and iha were widely distributed throughout all strains, whereas katP, stcE, and efa1 were more associated with the presence of eae and subA with the eae-negative strains. A great proportion of eae-negative strains were isolated from adults -dairy and grazing farms- and fromrearing calves -dairy and feedlot-, whilemostly of the eae-positive strains were isolated from dairy young calves. Data exposed indicate a correlation between the category of the animal and the production systems with the presence or absence of several genes implicated in adherence and virulence of STEC.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242521,"idioma_id":5,"titulo":"Medianeras","resumen":"El artículo indaga en una condición que Buenos Aires comparte con muchas otras grandes ciudades pero que aquí ha sido históricamente percibida como un problema: la visibilidad de las medianeras. A través del análisis de diferentes códigos urbanísticos -incluido el actualmente en discusión-, de ejemplos arquitectónicos y de voces celebratorias, reflexivas o detractoras, cuestionamos el lugar común desde el que la medianera se convirtió en el elemento más denigrante del paisaje urbano, y exploran nuevos modos de entenderla como parte de ese paisaje.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242522,"idioma_id":5,"titulo":"Grandes Proyectos Urbanos y su relación con la ciudad: el caso de Puerto Norte (Rosario, Argentina)","resumen":"Los Grandes Proyectos Urbanos (GPU) son uno de los instrumentos predilectos del urbanismo contemporáneo. Generalmente producto de la recualificación de ex áreas industriales, o zonas que perdieron sus usos y fueron relegadas, son a la vez ocasiones preciadas para los estados locales que suelen convertir áreas problemáticas en brillantes nuevas centralidades y también extraordinarias oportunidades de multiplicación de capital. Una crítica frecuente desde los estudios urbanos apunta a la relación que se establece entre los GPU y las ciudades que los albergan: la imputación de los GPU como casos de fragmentación urbana. Sin embargo, a pesar de ser éste un juicio usual, existen pocos estudios que lo toman como un problema central. Aquí se propone examinar el caso de Puerto Norte desde esta perspectiva; indagar cómo se vincula con la ciudad de Rosario, y particularmente analizar su  relación con el río Paraná, principal recurso paisajístico y recreativo de la ciudad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242526,"idioma_id":5,"titulo":"Medianeras","resumen":"El artículo indaga en una condición que Buenos Aires comparte con muchas otras grandes ciudades pero que aquí ha sido históricamente percibida como un problema: la visibilidad de las medianeras. A través del análisis de diferentes códigos urbanísticos -incluido el actualmente en discusión-, de ejemplos arquitectónicos y de voces celebratorias, reflexivas o detractoras, cuestionamos el lugar común desde el que la medianera se convirtió en el elemento más denigrante del paisaje urbano, y exploran nuevos modos de entenderla como parte de ese paisaje.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242527,"idioma_id":5,"titulo":"Grandes Proyectos Urbanos y su relación con la ciudad: el caso de Puerto Norte (Rosario, Argentina)","resumen":"Los Grandes Proyectos Urbanos (GPU) son uno de los instrumentos predilectos del urbanismo contemporáneo. Generalmente producto de la recualificación de ex áreas industriales, o zonas que perdieron sus usos y fueron relegadas, son a la vez ocasiones preciadas para los estados locales que suelen convertir áreas problemáticas en brillantes nuevas centralidades y también extraordinarias oportunidades de multiplicación de capital. Una crítica frecuente desde los estudios urbanos apunta a la relación que se establece entre los GPU y las ciudades que los albergan: la imputación de los GPU como casos de fragmentación urbana. Sin embargo, a pesar de ser éste un juicio usual, existen pocos estudios que lo toman como un problema central. Aquí se propone examinar el caso de Puerto Norte desde esta perspectiva; indagar cómo se vincula con la ciudad de Rosario, y particularmente analizar su  relación con el río Paraná, principal recurso paisajístico y recreativo de la ciudad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242545,"idioma_id":5,"titulo":"El cogito y la conciencia. Lo escópico y las particularidades del mundo onírico","resumen":"El objetivo del artículo es analizar los estatutos del cogito y de la conciencia desde el punto de vista escópico, en la disyunción entre vida diurna y experiencia onírica. La metodología, de tipo teórico, consiste en el análisis de algunos textos filosóficos y psicoanalíticos a partir de una serie de problemas esbozados. Comenzamos por interrogar el lugar argumental del sueño en la concepción de una conciencia heterótopa, apoyándonos en teorizaciones de Lacan y Sartre; el fin es avanzar sobre la dificultad de pensar una conciencia no unitaria, por el enmascaramiento que el yo produce. Como contrapartida, el fenómeno onírico es un argumento crucial para concebir una conciencia sin yo. La discrepancia del lugar del cogito respecto del sueño y la locura nos allana el camino para mejor dilucidar la relación entre cogito y sueño. Desbrozamos luego el planteo del mundo como omnivoyeur pero no exhibicionista a partir de las distinciones efectuadas. Concluimos que el sueño como fenómeno escópico debe circunscribirse a la ausencia de soporte narcisista como anclaje de un sujeto, pues el sujeto geometral cartesiano está diseminado en las imágenes del sueño; la captación del cogito cartesiano es, pues, sólo escópica en el sentido restringido de la vida diurna.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242547,"idioma_id":5,"titulo":"Comparación de las reacciones adversas en la asociación ketamina-propofol (ketofol) 1:4 versus 1:2 en procedimientos de baja complejidad","resumen":"Ketamina produce analgesia complementando la sedación del Propofol durante la anestesia buscando ventilación espontánea y una recuperación más rápida.El presente trabajo busca determinar la proporción de ketamina-propofol (ketofol) con menores reacciones adversas, en colonoscopias y legrados.Se realizó un estudio retrospectivo, descriptivo y observacional. Se analizaron historias clínicas en el periodo febrero 2015 a febrero 2017 de pacientes sometidos a videocolonoscopías y\/o legrados uterinos, siguiendo el protocolo de ketofol para sedo analgesia del Servicio de Anestesia del Hospital Misericordia. Fueron divididos en 2 grupos: Grupo A Ketofol 1:2, se administró una mezcla de 100 mg de ketamina y 200 mg de propofol y Grupo B Ketofol en proporción 1:4, 50 mg de ketamina y 200 mg de propofol. Se analizaron las reacciones adversas: apnea, hipotensión, hipertensión, bradicardia, taquicardia, desaturación de oxígeno periférica y depresión ventilatoria; y aquellas producto de las drogas utilizadas, denominadasReacciones Adversas Medicamentosas (RAM) las que incluyeron náuseas, vómitos, mareos, nistagmo, espasmos musculares o mioclonías, y reacciones psicomiméticas (agitación, desorientación y alucinaciones). El 70% del Grupo A tuvo alguna reacción adversa y del Grupo B sólo el 29% (p&lt;0,05). En ambos grupos la más frecuente fue la desaturación de oxígeno, sin diferencias significativas. Sólo hubo apneas (p=0,0022), hipertensión arterial (p=0,072), desorientación (p=0,0183), agitación (p=0,145) y bradicardia (p=0,3065) en el Grupo A. No hubo diferencias significativas en relación a hipotensión arterial (p=0,6844). El 42% de los pacientes del Grupo A presentó alguna RAM; la tercera parte de estas fueron ?mareos?, también hubo presencia de nistagmo en un 15% y mioclonía en tan solo un caso. En el caso del Grupo B, el porcentaje de RAM fue de 18% la mitad presentó mareos y la otra nistagmo. Las diferencias fueron significativas (p=0,0267). La proporción óptima de ketofol para la administración de una sola jeringa aún sigue en estudio. En este trabajo pudimos comprobar que la proporción 1:4 produce significativamente una menor cantidad de reacciones adversas en los pacientes que la proporción 1:2.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242548,"idioma_id":5,"titulo":"Análisis de variables hemodinámicas utilizando la combinación ketamina-propofol (ketofol) en procedimientos de baja complejidad","resumen":"La colonoscopía, gold Standard para determinar patologías del tracto gastrointestinal bajo es un proceso doloroso. La sedoanalgesia es recomendada. La asociación de drogas tiene como finalidad, potenciar efectos benéficos y reducir reacciones adversas. La combinación Ketamina-Propofol es un ejemplo clínico de sinergia de dos drogas.El objetivo de este estudio fue observar modificaciones en las variables hemodinámicas segun distintas combinaciones Ketamina-Propofol y evaluar grado de sedación, hemodinamia, y comportamiento respiratorio.Se realizó un estudio retrospectivo, descriptivo y observacional. Se analizaron historias clínicas en el periodo febrero 2015 a febrero 2017 de pacientes sometidos a videocolonoscopías y\/o legrados uterinos. Fueron divididos segun relacion de dosis ketamina-propofol en 2 grupos : Grupo A (n:33) Ketofol 1:2 (0,5mg\/Kg. de Ketamina, 1mg\/Kg. de Propofol) y Grupo B (n:34) Ketofol en proporción 1:4 (0,25mg\/Kg. de Ketamina, 1mg\/Kg. de Propofol). Se valoro el comportamiento ventilatorio a traves de oximetria y frecuencia respiratoria y el grado de sedacion por Escala de Ramsay.El perfil de la frecuencia respiratoria para los dos grupos muestra que las medias en el Grupo A, resultaron mayores que en el Grupo B. las diferencias resultaron estadísticamente significativas (p=0,0012). La saturación de O2 tuvo valores medios superiores en el Grupo A, a partir de los 5 minutos de la inducción. Finalizado el procedimiento los valores medios de la saturación de O2 fueron muy semejantes. En los perfiles de la Frecuencia Cardiaca media valores superiores en el Grupo A, siendo muy próximos a los 30 minutos y finalizado el procedimiento. No resultaron significativas las diferencias (p=0,5408). Los valores de las medias de la tensión arterial sistólica (TAS) y tensión arterial diastólica (TAD), fueron semejantes en los dos grupos y el valor de p, resultó significativo (p&gt;0,05). Siendo estos hallazgos coincidentes a los de Aydogmus y col y de Wang.La evidencia positiva confirma su perfil seguro, pero la mayoría de los estudios se concentraron en la dosis baja de Ketamina, mostrando propiedades sinérgicas, sin su perfil de efectos secundarios. En esta etapa, el uso de Ketofol en proporción 1:4 (0,25mg\/Kg. de Ketamina, 1mg\/Kg. de Propofol) puede ser un valor seguro, de acuerdo con todos los resultados mostrados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242549,"idioma_id":5,"titulo":"Los Impactos del Turismo en Tupungato: Una mirada Sustentable","resumen":"El artículo Los Impactos del Turismo en Tupungato: Una mirada Sustentable, parte de una primera reflexión luego de la obtención de los primeros resultados preliminares en la investigación llevada a cabo por los autores del mismo. En él se destaca la metodología de investigación implementada en torno a evaluar el desarrollo sustentable de un destino turístico emergente como es el caso del departamento de Tupungato de la región Valle de Uco, a fin de comprobar si los conceptos vertidos en la hipótesis de investigación guardan relación con el grado de desarrollo socio-cultural, económico y ambiental observados en los distintos actores que intervienen.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242551,"idioma_id":5,"titulo":"TEMPORAL VARIATION IN FAECAL N-ALKANE RATIOS AND ESTIMATION OF PASTURE INTAKE IN CALVE","resumen":"SUMMARY The temporal variation (between and within sampling days) in the faecal n-alkane ratios (C32\/C31 and C32\/C33), and the effectof AM or PM faecal sampling on the estimation of pasture intake, was studied in Holstein-Friesian calves in two independenttrials. In Study 1, calves strip-grazed at different pasture allowances: Low or High (2.5 or 7.5 kg DM\/100 kg LW\/day). In Study2, calves strip-grazed at different grazing time schedules but same total daily pasture allowance (4-h: one fresh grazingarea\/day for 4 h (11:00 AM to 3:00 PM) at a pasture allowance of 4.2 kg DM\/100 kg LW, or 2x2-h: two fresh grazingareas\/day, each one for 2 h (11:00 AM to 1:00 PM and 3:00 PM to 5:00 PM) at a pasture allowance of 2.1 kg DM\/100 kg LW).In both trials, calves (LW range: 117-173 kg) were dosed orally with C32 embedded in paper stoppers twice a day. Thevariation between days in the faecal n-alkane ratios, estimated from the coefficient of variation (CV, %) over days 7 to 12(Study 1) or 6 to 10 of dosing (Study 2), was not significantly different between pasture allowances (Low: 17%, High: 14%) orgrazing time schedules (4-h: 16%, 2x2-h: 12%). In both studies, AM had significantly lower faecal n-alkane ratios than PM(p<0.01), therefore, significantly higher pasture intakes were estimated from AM compared with PM (Study 1: p<0.01, Study2: p<0.001). The magnitude of the variation within sampling days in the faecal n-alkane ratios indicates that, in calves, morethan one faecal sample per day should be taken to obtain a more reliable estimation of pasture intake under similar grazingconditions. In Study 1, the time required for the faecal concentration of C32 to reach stable levels was very short (day 2 ofdosing), and suggests that the faecal sampling in calves might begin earlier than in present recommendations.Key words. n-alkanes, grazing, intake, calves.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242552,"idioma_id":5,"titulo":"Conflictos Territoriales y Autismo Institucional  Distrito El Algarrobal-Las Heras","resumen":"Las acciones de los gobiernos locales se reflejan en el territorio ya sea a corto, mediano y\/o largo plazo, brindándoles mejoras o no a la calidad de vida de su comunidad. Una de las situaciones que se detectan en muchos casos es la ausencia de gestiones de las instituciones responsables, lo que generalmente produce daños, que suelen ser irreversibles por el importante pasivo ambiental que dejan.El área de estudio presenta en la actualidad una extensa superficie explotada económicamente  con actividades dañinas al territorio como son las ladrilleras y el tratamiento informal de Residuos Sólidos Urbanos fundamentalmente, habiendo avanzado en los últimos años especialmente sobre las parcelas que tenían producción agrícola. Esta situación tan visible, desde el sector público no es advertida y por ende tampoco controlada, lo que en cierto modo permite que continúe  el proceso de degradación ambiental. La situación planteada y algunos antecedentes bibliográficos que reflejan claramente esta realidad desde hace años, fue lo que impulsa la propuesta de investigación, cuyo objetivo ha sido diseñar una macrozonificación, en base a un diagnostico situacional de la dinámica territorial, construido con información cartográfica, estadística, antecedentes bibliográficos, datos de organismos públicos y relevamientos de campo.A partir de los resultados obtenidos se ha podido esbozar una propuesta que incorpore alternativas de mejoramiento en cada una de las macrozonas, a fin de ser consideradas por la institución municipal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242558,"idioma_id":5,"titulo":"Variaciones sobre el deseo. Colonialismo, zona de no ser y plano de inmanencia","resumen":"El trabajo se concentra enel problema del deseo en la escritura fanoniana y sus proyecciones al espaciode la filosofía de Deleuze y Guattari. Sostenemos que la figura del deseo enlos escritos fanonianos se transforma poco a poco desde una idea del deseoarticulado a partir de la idea de falta hacia un deseo como positividad, elcual se adecua a las condiciones poscoloniales de la imaginación política ycoincide, desde otras marcas analíticas, con las formas en que Deleuze-Guattaripensaron el problema del plano de inmanencia. Esto hace que ambos itinerariosintelectuales y sus escrituras se precisen. En ese pasaje ocurren dos procesoscruciales, el primero es la crítica de las lógicas compensatorias de lascategorías frente al colonialismo y el segundo es la crítica de larepresentación. Al final sugerimos que ambas escrituras logran conjurar estosprocesos a partir de producir espacios no normados por la relaciónmodernidad-colonialidad. &nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242559,"idioma_id":5,"titulo":"Sueño, chiste y lazo social. Acerca de la escritura.","resumen":"A través del relato de un sueño se intenta dar cuenta del hecho de que las formaciones del inconsciente son posibles en cuanto hay sujetos implicados en un lazo social. Así como el chiste es tal porque hay alguien que lo sanciona con su risa, el sueño, cuando es relatado, se vuelve texto para ser leído. Estas formaciones son recursos del sujeto para no quedar atrapado cuando se ve sin salida por un acercamiento a lo real. Lo real se presenta como límite y detiene la escritura. Pero también es condición de posibilidad para la producción subjetiva.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242561,"idioma_id":5,"titulo":"Metodología para el relevamiento de los espacios verdes públicos en la ciudad de Luján, Provincia de Buenos Aires","resumen":"Los espacios verdes públicos son lugares de esparcimiento que resultan fundamentales para mejorar la  calidad  de  vida  en  las  ciudades.  En  las  últimas  décadas  su  gestión  y  planificación  han  cobrado relevancia  por  los  beneficios  que  generan.  La  metodología  aquí  presentada  surge  como  un  aporte para el conocimiento de  las áreas  verdes en un  sector de  la ciudad de Luján, Provincia de Buenos Aires. En este sitio piloto que incluyó a seis  barrios céntricos, se determinaron  los espacios  verdes públicos,  se  estableció  una  tipología  con  cinco  categorías  y  se  creó  un  indicador  de  calidad compuesto por once variables cualificables, estableciendo un valor para cada sitio. Los datos fueron relevadosdurante las salidas a campo y se integraron a un SIG, donde se analizaron espacialmente para generar  cartografía temática. La información generada fue entregada al municipio de Luján.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242562,"idioma_id":4,"titulo":"PROFILE OF THE ADULT POPULATION OF THE CITY OF CORRIENTES (ARGENTINA) IN RELATION TO DENTAL HEALTH INSURANCE","resumen":"Objective: To characterize the adult population of the city of Corrientes (Argentina) in relation to dental health insurance according to sociodemographic and dental variables. Materials and Methods: A descriptive cross-sectional study was conducted in the city of Corrientes (Argentina). Information regarding the study variables was collected through the application of a structured survey. Sample size was determined by establishing a 95% confidence level (381 subjects between 35 and 44 years of age). The direct face-to-face observation technique was used for data collection. A simple random sample design was applied for the selection of the homes to be surveyed, which was complemented by a non-probabilistic sampling using quotas for the selection of the individuals to be interviewed from the 2010 Population Census data. Results: Of the total of the participants, 56.4% had dental health insurance. Health insurance was significantly associated with a higher socioeconomic level OR: 1.90 (95% CI 1.26-2.87, p=0.01); greater probability of having had a consultation in the 12 months prior to the interview OR: 1.74 (95% CI 1.13-2.68, p=0.01), going to the dentist for dental treatments OR: 1.5 (95% CI 1.02-2.43, p=0.03), or because of pain or an emergency problem OR: 1.59 (95% CI 1.05-2.42, p=0.02), and presenting better oral hygiene self-care. Conclusions: There are oral health inequities in the adult population of the city of Corrientes (Argentina). Having dental health insurance is associated with a higher socioeconomic level, having more frequent dental consultations to get dental treatment and in emergency situations, as well as presenting better oral hygiene self-care.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242563,"idioma_id":5,"titulo":"DETERMINANTES SOCIALES QUE INFLUYEN EN LA UTILIZACIÓN DEL HILO DENTAL","resumen":"Introducción: El uso del hilo dental es un método eficaz de remoción de la placa bacterianapresente en las superficies interproximales para prevenir la caries dental y la enfermedadperiodontal.Objetivo: analizar la influencia de distintos factores en la utilización diaria del hilo dental enindividuos de 35 a 44 años de edad que viven en la Ciudad de Corrientes, Argentina.Métodos: Se realizó un estudio transversal de base poblacional. La información se recolectó através de una encuesta domiciliaria sobre conocimientos, actitudes y hábitos de salud bucal,donde figuran las variables de estudio. Se determinó el tamaño de la muestra estableciéndose unnivel de confianza del 95%. Se entrevistó a 381 individuos. Se aplicó un diseño muestralpolietápico. Se analizaron los datos con los programas SPSS 21.0 y Epidat 3.1.Resultados: Se halló que el 29% de los entrevistados utilizan diariamente hilo dental. Elconocimiento de salud bucal; tener cobertura social y haber realizado una consulta odontológicaen los últimos 12 meses anteriores a la entrevista, se asociaron significativamente al uso diariodel hilo dental.Las personas de nivel socioeconómico bajo presentaron hábitos menos adecuados de utilización.El sexo no resultó ser una variable significativa.Conclusiones: Los programas de salud bucal, deberían contemplar los factores que influyen enla utilización diaria del hilo dental para que esta práctica se refleje en la población en estudio.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242566,"idioma_id":5,"titulo":"A viva voz y con todo el cuerpo. Lectura en voz alta y narración oral en escenarios escolares","resumen":"Este artículo da cuenta de un itinerario de formación destinado a estudiantes de primer año de las carreras de Profesorado de Educación Primaria y Educación Inicial que se dictan en la Universidad Nacional del Sur. La experiencia parte de la búsqueda y recopilación de textos de transmisión oral, recala en la factura artesanal de libros y se extiende hacia prácticas de lectura en voz alta y narración oral en escuelas primarias y jardines asociados. En el recorrido se van entramando la observación participante en contextos reales de actuación, la reflexión sobre oralidad, lectura y escritura, sus complejas hibridaciones, las diferencias entre contar cuentos y leer en voz alta y la centralidad del cuerpo en la práctica docente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242568,"idioma_id":4,"titulo":"Effects of pollution and bioleaching process in the mineral composition and texture of contaminated sediments of the Reconquista River, Argentina","resumen":"In this work, we report on the structural and textural changes in fluvial sediments from Reconquista river basin, Argentina, due to processes of contamination with organic matter and remediation by bioleaching. The original uncontaminated matrix showed quartz and phyllosilicates as the main primary mineral constituents and phases of interstratified illite-montmorillonite as secondary minerals. It was found that in contaminated sediments, the presence of organic matter in high concentration causes changes in the specific surface area, particle size distribution, size and distribution of micro and meso and the morphology of the particles with respect to the uncontaminated sediment. After the bioleaching process, there were even greater changes in these parameters at the level of secondary mineral formation and the appearance of nanoparticles, which were confirmed by SEM. Especially, we found the formation of cementing substances such as gypsum, promoting the formation of macroporous aggregates and the weathering of clay components. Our results indicate that the bioleaching not only decrease the content of metals but also favors the formation of a material with improved characteristics for potential future applications.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242569,"idioma_id":5,"titulo":"LAS REDES COMO ESTRATEGIA DE INTERNACIONALIZACIÓ N UNIVERSITARIA EN EL MERCOSUR. EL CASO DE LA RIESAL (2013-2017)","resumen":"La internacionalización de la Educación Superior y las universidades es un proceso complejo, donde intervienen tendencias globales, políticas regionales y dinámicas institucionales, que a partir del último cuarto del siglo XX, en el contexto de globalización, adquieren características específicas entre las cuales la Regionalización es una de sus variantes. El objetivo de artículo consiste en analizar la importancia de orientar la internacionalización de la Educación Superior y la Universidad, hacia la integración regional desde una perspectiva no hegemónica (solidaria, endógena, colaborativa). En este sentido, se destaca la relevancia que adquieren las redes de producción y difusión de conocimiento como instrumento de internacionalización integral, promovidas desde el ámbito regional por el Núcleo de Estudios e Investigaciones en Educación Superior del Sector Educativo del Mercosur (NEIES). Particularmente, se describe la experiencia de la Red de Estudios sobre Internacionalización de la Educación Superior en   América Latina (RIESAL), que aborda la internacionalización a partir de dos  aspectos: 1) analítico y 2) propositivos. Finalmente, se destacan los elementos que contribuyen al proceso de internacionalización y los obstáculos que se deben superar para llevar adelante este proceso en forma exitosa, en función de la planificación estratégica de la Universidad, del país y de la Región que lo contiene.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242570,"idioma_id":4,"titulo":"A new species of poison-dart frog (Anura: Dendrobatidae) from Manu province, Amazon region of southeastern Peru, with notes on its natural history, bioacoustics, phylogenetics, and recommended conservation status   A new species of poison-dart frog (Anura","resumen":"We describe and name a new species of poison-dart frog from the Amazonian slopes of the Andes in Manu Province, Ma-dre de Dios Department, Peru; specifically within the Amarakaeri Communal Reserve and the buffer zone of Manu Na-tional Park. Ameerega shihuemoysp. nov. is supported by a unique combination of characters: black dorsum with cream to light orange dorsolateral lines, blue belly reticulated with black, and the lack of axillary, thigh and calf flash marks. Within Ameerega, it shares the general appearance of A. altamazonica, A. boliviana, A. hahneli, A. ignipedis, A. petersi, A. picta, A. pongoensis, A. pulchripecta, A. simulans, A. smaragdina, and A. yungicola; each possessing a granular black to brown dorsum, a light labial bar, a conspicuous dorsolateral line running from the snout to the groin, and a metallic blue belly and underside of arms and hind limbs. From most of these species it can be distinguished by lacking flash marks on the axillae, thighs, and calves (absent in only A. boliviana and A. smaragdina, most A. petersi, and some A. pongoensis), by having bright cream to orange dorsolateral stripes (white, intense yellow, or green in all other species, with the excep-tion of A. picta), and by its blue belly reticulated with black (bluish white and black in A. boliviana,green and blue with black marbling in A. petersi, and green and blue lacking black marbling in A. smaragdina). Its mating call also shows clear differences to morphologically similar species, with a lower note repetition rate, longer space between calls, and higher fundamental and dominant frequencies. Phylogenetic analyses based on the 16S mitochondrial rRNA fragment also sup-port the distinctiveness of the new species and suggest that A. shihuemoy is most closely related to Ameerega macero, A. altamazonica, A. rubriventris, and two undescribed species (Ameerega sp. from Porto Walter, Acre, Brazil, and Ameeregasp. from Ivochote, Cusco, Peru). Genetically, the new species is most similar to the sympatric A. macero, from which it clearly differs in characteristics of its advertisement call and coloration. The new species is found near rocky streams dur-ing the dry season and near temporary water bodies during the rainy season. Tadpoles are found in lentic water along streams, or in shallow, slow-moving streams. Given its small geographic range, we recommend that A. shihuemoy should be considered 'Near threatened' (NT) according to IUCN Red List criteria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242574,"idioma_id":4,"titulo":"Afforested sites in a temperate grassland region: influence on soil properties and methane uptake","resumen":"Methane (CH4) flux at the soil-atmosphere interface (SAI) results from the balance between CH4 production (methanogenesis) and CH4 consumption (methanotrophy). The latter predominates in well-aerated mineral soils; is affected by a combination of abiotic and biotic factors, especially soil diffusivity, which depends on soil properties, and methanotroph activity. This work reports results of CH4 fluxes from afforested sites located in a temperate region of formerly native grassland in Buenos Aires Province (Argentina, Southern Hemisphere), taking a naturalized pasture as a reference. Methane concentration [CH4] and soil parameters along the soil profile were also measured to understand intersite differences in CH4 fluxes at the SAI, that could be related to vegetation cover and its influence on soil properties and therefore, on CH4 soil diffusivity. At all sites soils were CH4 sinks in the range of &#8722;3.55 to &#8722;14.39 ng CH4 m&#8722;2 s&#8722;1; the naturalized pasture presented the weakest one. Intersite differences in CH4 fluxes may result from differences observed in [CH4] profiles and CH4 diffusion coefficients. [CH4] variation could be explained mainly by differences in silt and clay content and bulk density that affect CH4 soil diffusivity. These could be the result of afforestation that seems to improve the physical and biological soil attributes linked to CH4 consumption as it meliorates its diffusivity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242576,"idioma_id":5,"titulo":"Los usos sociales del pasado en la construcción nacional-estatal: la representación de la propuesta de una monarquía incaica (1816) en la historiografía de Mitre","resumen":"La propuesta de Belgrano de instaurar una monarquía incaica en el espacio de las Provincias Unidas generó en 1816 debates tanto en el Congreso de Tucumán como en la prensa periódica porteña. Sin embargo, este hecho ha recibido tradicionalmente, en la narrativa hegemónica, un lugar muy acotado y condicionado por la interpretación que Mitre realizó en su obra considerada fundacional de la historiografía argentina. A los fines de indagar acerca del ?Plan del Inca? como evento histórico, resulta imprescindible deconstruir dicha versión, para lo cual retomamos diversas herramientas provenientes de los Estudios de Memoria. Desde el análisis de los ?usos sociales del pasado?, consideramos a la labor historiográfica de Mitre como una acción de ?traer el pasado al presente?, influida por el objetivo de crear una historia nacional y por diversos intereses vigentes en la segunda mitad del siglo XIX, y señalamos diversos mecanismos que subyacen a la construcción del relato mitrista.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242577,"idioma_id":5,"titulo":"Mercado de trabajo y desigualdad en la Argentina. Un balance de las últimas tres décadas","resumen":"El documento analiza las tendencias y determinantes de los indicadores laborales más relevantes como así también de la distribución del ingreso y de la pobreza en la Argentina desde la década de los noventa hasta el presente. Se concluye que a pesar de las importantes mejoras exhibidas por estas dimensiones luego del colapso de la convertibilidad, el panorama laboral y distributivo continúa siendo preocupante, en especial, considerando el menor dinamismo, e incluso reversiones, que algunas mejoras evidenciadas en la primera etapa del nuevo esquemamacroeconómico registraron en los últimos años.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242578,"idioma_id":5,"titulo":"El estancamiento de la tasa de participación económica femenina en Argentina en los años 2000","resumen":"Desde 1960 la tasa de actividad femenina ha venido registrando una tendencia creciente en Argentina, que se estanca desde principios de los años 2000; incluso se observa una leve disminución durante los últimos años de esa década y principios de la siguiente. Tal evolución contrasta con la experiencia internacional; Argentina se distingue incluso de prácticamente el resto de los países de la región en los cuales continuó el aumento de la participación femenina, aun cuando a una tasa menor que en el pasado. Este trabajo aborda el análisis de la participación económica femenina desde principios de los ochenta, pero focaliza su atención en el quiebre observado hacia principios de siglo. Se explorarán diversos factores que podrían haber influido sobre esa dinámica y, en particular, se examinarán posibles tipos de respuestas de diferentes grupos de mujeres en un contexto de mejoramiento global de las condiciones del mercado de trabajo ?como fue el período iniciado a principios del nuevo siglo? y de puesta en marcha de algunas políticas que, al menos potencialmente, pudieron haber ejercido algún papel.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242579,"idioma_id":5,"titulo":"Evaluación Cinemática de la Biomecánica de Rodilla en los Gestos de Lanzamiento en Jugadores de Básquet","resumen":"Introducción: En este trabajo se estudia las relaciones entre el varo\/valgo, flexión\/extensión y rotación interna\/externa de rodilla en los a jugadores de básquet durante movimientos de lanzamiento. Material y Método: Se realizó el registro de siete sujetos masculinos, jugadores amateur de básquet. Cada uno ejecutó cinco lanzamientos de tiro simple y en carrera. Se evaluó la influencia en el movimiento varo\/valgo de estos gestos. Resultados: Se encontró que en ambos casos existe una mayor tendencia al valgo, con un 69% para el lanzamiento simple y un 80% para el lanzamiento simple con carrera. Se registró para la pierna izquierda mayor movimiento de valgo de rodilla que para la pierna derecha. Se encontró que el 78% de los registros en lanzamiento simple y el 93% lanzamiento con carrera realizan un movimiento de valgo para la rodilla izquierda. Conclusión: Al comparar los ángulos máximos de flexión\/extensión y de rotación interna\/externa con los ángulos máximos varo\/valgo se encontró una débil correlación entre el ángulo varo\/valgo y el ángulo de rotación interna\/externa, como así también entre el ángulo varo\/valgo y el ángulo de flexión\/extensión en rodilla, para los dos gestos de lanzamiento analizados. Nivel de evidencia: IV.Palabras clave: varo, valgo, rodilla, básquet, lesiones","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242580,"idioma_id":5,"titulo":"Diversidad y estructura genética poblacional del langostino argentino (Pleoticus muelleri) mediante el análisis de secuencias de ADN mitocondrial de región control","resumen":"El langostino argentino (Pleoticus muelleri) se distribuye a lo largo de las costas del Océano Atlántico Sudoccidental, entre los 20º y 40º de Latitud S. En Argentina constituye en la actualidad uno de los recursos de mayor importancia para la actividad pesquera. En la década de 1980 comienza su pesca en Patagonia, y a partir de la década de 1990, casi la totalidad del desembarque declarado de esta especie proviene de la pesquería patagónica (96%). El elevado valor comercial de este crustáceo en los mercados internacionales lo ha situado como uno de los principales productos de exportación pesquera argentina, representando una participación del 58,4% del total de exportaciones del sector, con un ingreso anual superior a los 1.000 millones de dólares estadounidenses (DEP-SPyA, 2017).En la actualidad, no se dispone de una caracterización genética del langostino (P. muelleri). Contar con la misma podría aumentar la plus valía del producto de exportación, y no se correría el riesgo de que se vea comprometida su comercialización en el futuro en un mercado competitivo, que demanda certificaciones que apliquen los últimos  avances tecnológicos disponibles en términos de trazabilidad.En este trabajo se analizaron 184 secuencia de la región control de ADN mitocondrial de 8 sitios de muestreos localizados a lo largo de su distribución geográfica. Se encontraron 82 haplotipos diferentes, siendo Rio Grande do Sul las mas variable (Hd=0,983) y Rio de Janeiro la menos variable (Hd=0,849). Los índices analizados indican que P. muelleri es una gran población panmíctica con un alto grado de flujo génico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242582,"idioma_id":5,"titulo":"Causalidad eficiente en el conocimiento intelectual actual según Juan Duns Escoto","resumen":"&lt;!-- \/* Font Definitions *\/@font-face{font-family:'&#65325;&#65331; &#26126;&#26397;';panose-1:0 0 0 0 0 0 0 0 0 0;mso-font-charset:128;mso-generic-font-family:roman;mso-font-format:other;mso-font-pitch:fixed;mso-font-signature:1 134676480 16 0 131072 0;}@font-face{font-family:'Cambria Math';panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:3 0 0 0 1 0;}@font-face{font-family:Cambria;panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:3 0 0 0 1 0;} \/* Style Definitions *\/p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-unhide:no;mso-style-qformat:yes;mso-style-parent:'';margin:0cm;margin-bottom:.0001pt;text-align:justify;text-justify:inter-ideograph;mso-pagination:widow-orphan;font-size:12.0pt;font-family:'Times New Roman';mso-fareast-font-family:'&#65325;&#65331; &#26126;&#26397;';mso-bidi-font-family:'Times New Roman';mso-fareast-language:JA;}.MsoChpDefault{mso-style-type:export-only;mso-default-props:yes;font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:Cambria;mso-ascii-font-family:Cambria;mso-fareast-font-family:'&#65325;&#65331; &#26126;&#26397;';mso-hansi-font-family:Cambria;}@page WordSection1{size:612.0pt 792.0pt;margin:72.0pt 90.0pt 72.0pt 90.0pt;mso-header-margin:36.0pt;mso-footer-margin:36.0pt;mso-paper-source:0;}div.WordSection1{page:WordSection1;}--&gt;El tema de la causalidad aparece en muchas de las solucionesque propone Duns Escoto a distintos problemas filosóficos, como el actovoluntario, y teológicos, como la dispensa divina de gracia en los sacramentos.En el presente trabajo nos proponemos mostrar el tipo de causas y causalidadque interviene en el acto de intelección actual. Para ello, centramos nuestraexposición en el concepto de orden esencial como fuente de las distintasmodalidades de concurrencia causal, y luego lo aplicamos al acto de intelecciónactual, interpretándolo desde la idea de unitasordinis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242583,"idioma_id":4,"titulo":"High performance preconcentration of inorganic Se species by dispersive micro-solid phase extraction with a nanosilica-ionic liquid hybrid material","resumen":"A highly sensitive and efficient dispersivemicro-solid phase extraction (D-&#956;-SPE)method was developed for inorganic Se speciation analysis. A novel ionic liquid (IL)-nanomaterial hybrid consisting of 1-dodecyl-3-methylimidazolium bromide-functionalized nanosilica was used for the efficient retention of Se(IV) complexed with ammonium pyrrolidine dithiocarbamate, followed by elution with an ethyl acetate\/Triton X-114 mixture and determination by electrothermal atomic absorption spectroscopy. The Se(VI) species was selectively determinedby difference between total inorganic Se and Se(IV) after pre-reduction. The IL-nanomaterial hybrid was characterized by Fourier transform infrared spectroscopy and transmission electronic microscopy. Likewise,Se(IV) sorption capacity of the retention material and maximum amount of IL loaded on its surface were determined.Several factors concerning the functionalization, extraction and elution steps were optimized, yielding a 100% extraction efficiency for Se(IV) under optimal conditions. A limit of detection of 1.1 ng L&#8722;1, a relative standard deviation of 5.7% and a 110-fold enhancement factor were obtained. The D-&#956;-SPE method was successfully applied to several water samples fromdifferent origins and compositions, including rain, tap, underground, river and sea.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242584,"idioma_id":4,"titulo":"Synergistic analytical preconcentration with ionic liquid-nanomaterial hybrids","resumen":"Nanomaterials and ionic liquids (ILs) have very attractive properties for improved analytical preconcentration methods. Thus, ILs have been used as excellent tools to functionalize nanomaterials, giving them specific chemical properties for higher selectivity, extraction efficiency and extended re-utilization in preconcentration. Moreover, incorporation of IL-nanomaterial hybrids in miniaturized solid phase and liquid phase microextraction procedures is being increasingly exploited to obtain high analytical recoveries while developing environmentally friendly analytical methods. In this review, the design and application of innovative and efficient analytical methods for sensitive and selective determination of inorganic and organic analytes is described. The synthesis of some IL-nanomaterial hybrids is presented along with a revision of the most important synergistic physicochemical properties useful for the extraction of analytes. Finally, practical considerations concerning the application of IL-nanomaterial hybrids for the development of modern analytical separation and preconcentration techniques are fully discussed in this work.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242585,"idioma_id":4,"titulo":"Polymer nanoparticles containing essential oils: new options for mosquito control","resumen":"Mosquitoes (Diptera: Culicidae) are vectors of important parasites and pathogens causing death, poverty and social disability worldwide. The overuse of synthetic insecticides to control mosquito vectors lead to resistance, adverse environmental effects and high operational costs. Therefore, the development of eco-friendly control tools is an important public health challenge. In this study, two different essential oils (EO) (geranium, Geranium maculatum, and bergamot, Citrus bergamia) loaded polymeric nanoparticle (PN) were elaborated using polyethylene glycol (PEG) and chitosan (Qx) as the polymeric matrix\/coating. In addition, the mosquito larvicidal acute and residual activity of the PN was evaluated on Culex pipiens pipiens. The physicochemical characterization of PN revealed that PEG-PN had sizes <255 nm and encapsulation efficiency between 68 and 77%; Qx-PN showed sizes <535 nm and encapsulation efficiency between 22 and 38%. From the toxicological test, it was observed that Qx-PN produced higher acute and residual activity than PEG-PN. Overall, this study highlights that polymer nanoparticles containing essential oil are a promising source of eco-friendly mosquito larvicidal products.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242586,"idioma_id":4,"titulo":"Efficacy of essential oils to control the Indian meal moth, Plodia interpunctella (H&uuml;bner) (Lepidoptera: Pyralidae)","resumen":"Essential oils (EOs) have been recognized as an important source of biopesticides. This work investigated the chemical constituents and bioactivity of six essential oils namely lavender (Lavandula angustifolia Mill.), peppermint (Mentha piperita L.), geranium (Geranium maculatum L.), palmarosa (Cymbopogon martinii (Roxb.) Wats), eucalyptus (Eucalyptus globulus Labill.) and bergamot (Citrus bergamia Risso) against adults of the Indian meal moth, Plodia interpunctella, a cosmopolitan pest that infests a wide range of stored products. Analysis by gas chromatography coupled to mass spectrometry (GC?MS) revealed the presence of several compounds, mainly mono- and sesquiterpenes. The contact toxicity assay showed that the EO from palmarosa was the most toxic with a LD50 value of 22.8 &#956;g cm&#8722; 2. The toxicity order was palmarosa > geranium > peppermint > lavender > bergamot > eucalyptus. In fumigant toxicity assay, the greatest effect was found with the EO from eucalyptus with a KT50 value of 8.34 min. The toxicity order was eucalyptus > peppermint > geranium = lavender > bergamot > palmarosa. The EO from palmarosa showed the highest residual activity when the insects were exposure to its volatiles constituents. Finally, all EOs produce sublethal activity promoting effects in the fecundity. In conclusion, the EOs could be used as potential biopesticides for P. interpunctella control.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242587,"idioma_id":4,"titulo":"Biofilm formation and antimicrobial resistance genes of coagulase-negative staphylococci isolated from cows with mastitis in Argentina","resumen":"Mastitis affects the health and welfare of dairy cows worldwide. Coagulase-negative staphylococci (CNS) are known to formbiofilms and are increasingly recognized as a cause of persistent bovine intramammary infections. A total of 90 CNSisolated from cows with clinical and subclinical mastitis in Argentina from 2008 to 2014 were identified by PCR-RFLP usingthe gap gene. Standard microtiter plate assays were used to assess CNS biofilm formation, and Staphylococcus haemolyticusspecies formed the strongest biofilms. The presence of biofilm-associated genes icaA, bap and aap was detected in a fewisolates, while embP, fbe, atlE and eno were present in the majority of isolates. Genes encoding resistance to &#946;-lactams weredetected among the isolates; blaZ, mecA and mecC were detected in 21, 4 and 1 isolate, respectively. Resistance to macrolidesand lincosamides (n = 6) was attributable to ermB, ermC, mphC or mrsA or a combination of those genes. In this study, weidentified CNS species involved in mastitis and provide information about pathogenicity and antimicrobial resistance,which is essential to design efficient strategies to control mastitis caused by CNS.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242589,"idioma_id":5,"titulo":"El Comité de Vigilance des Intellectuels Antifascistes, la prensa periódica y L'esprit des annés trente","resumen":"El artículo examina el rol del Comité de Vigilancia de Intelectuales Antifascistas (C.V.I.A.) constituido en Francia en marzo de 1934. Propone la hipótesis de que la acción del C.V.I.A. fue parte de un clima mayor de renovación de la vida intelectual y política francesa de los años ´30, y en él, ocupó un lugar importante en los debates referidos al surgimiento del fascismo; al pacifismo; a la tradición republicana y liberal; y al papel de los intelectuales en la lucha antifascista. Apoyado en el estudio de fuentes originales, se analiza la prensa periódica del período, tanto el boletín del C.V.I.A., Vigilance, como otras del campo más amplio del antifascismo cultural (Monde, Commune, Europe, Esprit, La Révolution Prolétarienne). Por último, se propone una reflexión historiográfica que vincula el estudio de los intelectuales con la Nueva Historia Política francesa.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242591,"idioma_id":4,"titulo":"WATER DIFFUSION AND HYDROLYSIS EFFECT ON THE STRUCTURE AND DYNAMICS OF EPOXY-ANHYDRIDE NETWORKS","resumen":"Epoxy-anhydride networks have been analyzed in terms of water uptake and degradation behavior by means of broadband dielectric spectroscopy and atomic force microscopy. It has been found that water absorption produces a chemical reaction in the polymer networks, in turn causing a plasticizing effect and changing their mechanical properties. We demonstrate that a non invasive dielectric spectroscopy analysis of the segmental dynamics can be performed in order to quantitatively describe the degradation effects, as well as their influence in the mechanical properties at the nanoscale.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242595,"idioma_id":5,"titulo":"El asesoramiento pedagógico un espacio posible para el análisis institucional en En.DOSSIER ESPECIAL DE LA REVISTA ARGENTINA DE EDUCACIÓN SUPERIOR (RAES) SOBRE PEDAGOGÍA UNIVERSITARIA","resumen":"n\/a","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242598,"idioma_id":4,"titulo":"Recovery process of Li, Al and Si from lepidolite by leaching with HF","resumen":"This work describes the development of a new process for the recovery of Li, Al and Si along with the proposal of a flow sheet for the precipitation of those metals. The developed process is comprised of lepidolite acid digestion with hydrofluoric acid, and the subsequent precipitation of the metals present in the leach liquor. The leaching operational parameters studied were: reaction time, temperature and HF concentration. The experimental results indicate that the optimal conditions to achieve a Li extraction higher than 90% were: solid-liquid ratio, 1.82% (w\/v); temperature, 123 °C; HF concentration, 7% (v\/v); stirring speed, 330 rpm; and reaction time, 120 min. Al and Si can be recovered as Na3AlF6 and K2SiF6. LiF was separated from the leach liquor during water evaporation, with recovery values of 92%.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242599,"idioma_id":4,"titulo":"Synthesis of lithium fluoride from spent lithium ion batteries","resumen":"Lithium (Li) is considered a strategic element whose use has significantly expanded. Its current high demand is due to its use in lithium ion batteries for portable electronic devices, whose manufacture and market are extensively growing every day. These days there is a great concern about the final disposal of these batteries. Therefore, the possibility of developing new methodologies to recycle their components is of great importance, both commercially and environmentally. This paper presents results regarding important operational variables for the dissolution of the lithium and cobalt mixed-oxide (LiCoO2) cathodes from spent lithium ion batteries (LIBs) with hydrofluoric acid. The recovery and synthesis of Co and Li compounds were also investigated. The dissolution parameters studied were: temperature, reaction time, solid-liquid ratio, stirring speed, and concentration of HF. The investigated recovery parameters included: pH, temperature, and time with and without stirring. The final precipitation of lithium fluoride was also examined. The results indicate that an increase in the HF concentration, temperature, and reaction time favors the leaching reaction of the LiCoO2. Dissolutions were close to 60%, at 75ºC and 120 min with a HF concentration of 25% (v\/v). The recovery of Co and Li were 98% and 80%, respectively, with purities higher than 94%. Co and Li compounds, such as Co3O4 and LiF, were synthesized. Furthermore, it was possible to almost completely eliminate the F- ions as CaF2.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242600,"idioma_id":4,"titulo":"Early ciliary and prominin-1 dysfunctions precede neurogenesis impairment in a mouse model of type 2 diabetes","resumen":"Diabetes mellitus (DM) is reaching epidemic conditions worldwide and increases the risk for cognition impairmentand dementia. Here, we postulated that progenitors in adult neurogenic niches might be particularlyvulnerable. Therefore, we evaluated the different components of the mouse subventricular zone (SVZ) duringthe first week after chemical induction of type 1 and type 2 diabetes-like (T1DM and T2DM) conditions.Surprisingly, only T2DM mice showed SVZ damage. The initial lesions were localized to ependymal cilia,which appeared disorientated and clumped together. In addition, they showed delocalization of the ciliarymembrane protein prominin-1. Impairment of neuroprogenitor proliferation, neurogenic marker abnormalitiesand ectopic migration of neuroblasts were found at a later stage. To our knowledge, our data describe for thefirst time such an early impact of T2DM on the SVZ. This is consistent with clinical data indicating that braindamage in T2DM patients differs from that in T1DM patients.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242601,"idioma_id":5,"titulo":"Para comprender las situaciones de exilio.Perspectivas institucionales","resumen":"Se proponen perspectivas psicoanalítias e institucionales  para el análisis de procesos migratorios.Con aportes de Bleger, Grinberg León y Rebeca, Kaës, y Paola Valdemarin, se analiza someramente el caso que investiga Rosa Martha Romo Beltrán. Se trata de alguien que migra hacia Mexico en los tiempos de la última dictadora militar de Argentina, que se domina a sí misma ?autoexilada?,que ha desarrollado una carrera académica reconocida ,que ha decidido no regresar al país y que-en razón de tal complejo carácter- aporta material de interés  para comprender ,por lo menos en parte, algunas de las vicisitudes que introduce la culpa del abandono intencional, en el vínculo con los lugares de origen.Referentes analíticos-exilio-autoexilio-perturbación del duelo","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242602,"idioma_id":4,"titulo":"Designed nanoparticle-mesoporous multilayer nanocomposites as tunable plasmonic-photonic architectures for electromagnetic field enhancement","resumen":"In this work we present the designed production of a highly tunable nanocomposite able to confine and enhance the electromagnetic field through the combined effects of photonic and plasmonic responses. Silver nanoparticles (NPs) were embedded within a Mesoporous Photonic Crystal (MPC) composed of a mesoporous multilayer presenting a TiO2-SiO2 unit cell. This nanosystem was synthesized by a combination of reproducible sol-gel thin film techniques with the selective production of NPs within the titania layers. The design of the MPC architecture was tuned so that each photonic band gap edge would match the plasmonic absorption peak of the Ag NP, in order to combine their confined plasmonic enhancement with that of the band gap edges due to the multilayer structure. We find that the MPC contributes to enhancing the Surface Enhanced Raman Scattering (SERS) signal of probe molecules trapped in the mesopores. This effect indicates the relevance of the unit cell interfaces for the local electromagnetic field enhancements, and opens the gate to performing plasmon-assisted SERS sensing. The resulting material results in a promising platform to study the interplay between photonic and plasmonic systems. These tuneable nano-architectures are highly robust, reproducible, and can lead to applications in sensing platforms, as well as in optoelectronics, enhanced photocatalysis, or artificial photosynthesis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242603,"idioma_id":4,"titulo":"Structural and Mechanical Evolution of Mesoporous Films With Thermal Treatment: The Case of Brij 58 Templated Titania","resumen":"Mesoporous titania thin films (MTTFs) with well ordered cubic array of mesopores were synthesized on glass and silicon substrates using Brij 58 as a template. The effect of the thermal treatment and the substrate on the structural parameters (thickness, porosity, pore order, and crystallinity) and the mechanical properties of MTTFs were determined by electron microscopy, X-ray diffraction, Raman spectroscopy, 2D-small angle X-ray scattering, ellipsometric porosimetry, and nanoindentation. Clear differences in the mesostructural order evolution and crystallization behavior were observed as a function of the substrate and the thermal treatment. In particular, the anatase crystallization process occurs at lower temperatures for samples prepared on silicon when compared with samples prepared on glass, due to the balance between nanocrystals formation, mass diffusion, and Na+ migration from the substrate. As a consequence of such phenomena, the MTTFs mechanical properties are also dependent on the substrate. For samples prepared on glass the 325-350 °C range is the optimal annealing temperature to maximize the mechanical properties (E value of 45 GPa), while higher temperatures can be used for the Si supported oxides, to reach E values of 60 GPa. The obtained anatase crystal dimensions (below 4-5 nm) are restricted by the wall thickness, indicating the chosen thermal treatment prevents the mesoporous structure from collapsing even when the oxide presents thin walls and small pores, preserving high porosity and high porous ordering. As a consequence, the presented Brij 58 templated MTTFs exhibits smaller crystalline domains than analogous materials with thicker walls. Such properties could be exploited for applications in photocatalysis and titania-based solar cells.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242605,"idioma_id":4,"titulo":"Presence of trace elements in the silverside Odontesthes argentinensis","resumen":"The silverside Odontesthes argentinensis is an economically significant resource for commercial fisheries in South America. We evaluated the presence of trace elements in the stomach content and fish tissues (muscle and otoliths) of O. argentinensis. In addition, we assessed the presence of trace elements in its prey (zooplankton) and in seawater in a coastal temperate area. The most abundant trace elements found in the water, zooplankton, stomach content, and fish tissues (muscle and otoliths) constituted of Ba, Mn, Sr and Zn, while Cd, Cu and Pb were observed in lower concentrations. We concluded that O. argentinensis specimens captured from the environment, within the length range analyzed for muscle samples (total length: &lt;. 21. cm), are deemed fit for human consumption because the concentrations of trace elements mostly meet the standards established in the Argentine Food Code. The information obtained in this study is vital for O. argentinensis farming in closed systems.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242606,"idioma_id":4,"titulo":"Genetic population structure and evidence of genetic homogeneity in populations of the Argentinian silverside Odontesthes bonariensis (Teleostei: Atherinopsidae) inhabiting central and northwestern Argentina","resumen":"ABSTRACT. The study of species in their native geographic ranges is key to understanding how human activityhas influenced spatial fragmentation or species homogenization. The Argentinian silverside Odontesthesbonariensis, of interest for aquiculture and sport fishing, is a relevant subject of study. The species has beenintroduced in a number of countries and re-introduced in some areas of Argentina with unknown effects. Theobjectives of this study were to determine the population structure, genetic diversity (GD) and effectivepopulation sizes (Ne) of O. bonariensis in Argentina. Six microsatellite loci were amplified in individualscollected from four water bodies affected by commercial and sport fishing: Cabra Corral Reservoir (CC),Chascomús Lake (CH), Chasicó Lake (LCH) and the Río de la Plata (RLP). Three genetic groups were detected:one in CC, one in RLP and the last inhabiting CH and LCH. Interestingly, CH and LCH are located 768 kmapart, but showed no difference in allele frequencies; suggesting the introduction of individuals from CH intoLCH. The largest allele richness, GD and Ne were found in RLP indicating that the largest population of O.bonariensis may be found in this area. Current Ne were lower than historical Ne in all areas, suggesting a changein the GD over time. This study provides information on the genetic structure and genetic diversity of O.bonariensis across its native distribution and over time, demonstrating the first evidence of a possible genetichomogenization in this species probably linked to human activities.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242607,"idioma_id":4,"titulo":"ADHERENCE TO A GLUTEN FREE DIET IN CELIAC DISEASE: BIOMARKER DYNAMICS","resumen":"ADHERENCE TO A GLUTEN FREE DIET IN CELIAC DISEASE: BIOMARKER DYNAMICS Legorburu MC1 ; Saguir PF1 ; Gauna I2 ; Araujo CR1 1 Instituto de Bioquímica Aplicada. Facultad de Bioquímica Química y Farmacia. UNT. Balcarce 747. 2Hospital Centro de Salud Dr. Zenón Santillán. Sistema Provincial de Salud de Tucumán. Av Avellaneda 750. 4000. Tucumán. Argentina. E-mail: crosaraujo@hotmail.com Celiac disease (CD) is an autoimmune gluten dependent disorder that develops in genetically susceptible individuals carriers of HLA-DQ2 \/ HLA-DQ8. Clinical manifestations, seropositivity of biomarkers (BM) and specific histopathological changes confirm its diagnosis. Strict adherence to the gluten-free diet (GFD) is the only effective treatment. This work described the effects of adherence to the GFD in confirmed CD adult patients. It also shows the dynamics of BM, clinical biochemistry and endoscopic biopsy in a strict adherence situation for 13 years. Between 2003 and 2014, 1568 adults suspected of having CD were treated at the Gastroenterology Laboratory. In 17% (267), CD was confirmed by tissue transglutaminase- Isotype IgA greater than 20 U (cut-off manufacturer), ELISA method (Inova Diagnostics Inc, CA, USA). Only 16% (43) reported adherence to the GFD. In a retrospective cohort study, the dynamics of the BM was analyzed. Descriptive statistical analysis was applied. We found a significant decrease in the titles of BM, other biochemical markers and histological changes in an adult with confirmed CD (HLA - DQ2) at diagnosis and referral for strict adherence to the DLG was compared. Early diagnoses, strict adherence to GFD and monitoring of specific BM allows a redefinition of CD as a 'celiac condition.'","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242609,"idioma_id":5,"titulo":"Reflexión y análisis para un futuro cambio curricular de las carreras de Farmacia y Bioquímica en la Facultad de Bioquímica Química y Farmacia","resumen":"En este trabajo se abordan tópicos referidos al  Curriculum, de qué modo se configura, cuáles son sus alcances, qué factores determinan su cambio, cómo evoluciona, de qué manera se vincula con la práctica docente y cuáles son los requerimientos para su diseño y concreción.  Se incluye: una reseña cronológica de las reformas curriculares de la carrera de Farmacia;  reflexiones acerca de las concepciones del Curriculum y su evolución; análisis  sobre la oferta académica en las universidades argentinas y una propuesta para un posible cambio o adecuación futura del Diseño Curricular, DC, de las carreras de Farmacia y Bioquímica. El propósito es compartir este trabajo con toda la comunidad educativa y se espera que  se constituya en un elemento para el debate, que sea útil para el egresado novel que se inicia en la actividad docente y se reconozca la importancia del DC como documento que da sentido a la práctica. Esta propuesta ha surgido de la actividad de los Comités de Seguimiento y Coordinación vigentes de ambas carreras.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242612,"idioma_id":4,"titulo":"Mal de R&iacute;o Cuarto Virus Infection Triggers the Production of Distinctive Viral-Derived siRNA Profiles in Wheat and Its Planthopper Vector","resumen":"Plant reoviruses are able to multiply in gramineae plants and delphacid vectors encountering different defense strategies with unique features. This study aims to comparatively assess alterations of small RNA populations in both hosts upon virus infection. For this purpose, we characterized the small RNA profiles of wheat and planthopper vectors infected by Mal de Río Cuarto virus (MRCV, Fijivirus, Reoviridae) and quantified virus genome segments by RT-qPCR. We provide evidence that plant and insect silencing machineries differentially recognize the viral genome, thus giving rise to distinct profiles of virus-derived small interfering RNAs (vsiRNAs). In plants, most of the virus genome segments were targeted preferentially within their upstream sequences and vsiRNAs mapped with higher density to the smaller genome segments than to the medium or larger ones. This tendency, however, was not observed in insects. In both hosts, vsiRNAs were equally derived from sense and antisense RNA strands and the differences in vsiRNAs accumulation did not correlate with mRNAs accumulation. We also established that the piwi-interacting RNA (piRNA) pathway was active in the delphacid vector but, contrary to what is observed in virus-infected mosquitoes, virus specific piRNAs were not detected. This work contributes to the understanding of the silencing response in insect and plant hosts.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242613,"idioma_id":4,"titulo":"Complete genome sequence of Maize yellow striate virus, a new cytorhabdovirus infecting maize and wheat crops in Argentina","resumen":"A rhabdovirus infecting maize and wheat crops in Argentina was molecularly characterized. Through next-generation sequencing (NGS) of symptomatic leaf samples, the complete genome was obtained of two isolates of maize yellow striate virus (MYSV), a putative new rhabdovirus, differing by only 0.4% at the nucleotide level. The MYSV genome consists of 12,654 nucleotides for maize and wheat virus isolates, and shares 71% nucleotide sequence identity with the complete genome of barley yellow striate mosaic virus (BYSMV, NC028244). Ten open reading frames (ORFs) were predicted in the MYSV genome from the antigenomic strand and were compared with their BYSMV counterparts. The highest amino acid sequence identity of the MYSV and BYSMV proteins was 80% between the L proteins, and the lowest was 37% between the proteins 4. Phylogenetic analysis suggested that the MYSV isolates are new members of the genus Cytorhabdovirus, family Rhabdoviridae. Yellow striate, affecting maize and wheat crops in Argentina, is an emergent disease that presents a potential economic risk for these widely distributed crops.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242615,"idioma_id":5,"titulo":"Controversias acerca del test VIH para todos","resumen":"El 12 de enero de 2017, el Ministerio de Salud de la Nación Argentina publicó en el Boletín Oficial la Resolución 55 ? E\/2017 que dispone una serie de obligaciones y recomendaciones para los miembros de los equipos de salud con respecto a la realización del test del virus de inmunodeficiencia humana(VIH) y establece, entre otras cosas, la obligatoriedad de ofrecer el test en determinados casos y la no obligatoriedad de contar con una orden médica para acceder al testeo en el ámbito público de la República Argentina. De inicio, el análisis crítico de la resolución nos enfrenta a dos interrogantescentrales a responder: ¿cuál es la evidencia que sostiene las definiciones principales de la resolución? Y ¿cuáles son los potenciales daños que conlleva la misma? Más allá de los análisis y la falta de evidenciasduras que avalen la práctica, seguimos fortaleciendo el diálogo en el marco de las decisiones compartidas pero, a la vez, pensamos que hay que realizar un análisis detallado de las fortalezas,oportunidades, debilidades y amenazas del sistema, antes de emitir estas recomendaciones, además de brindar más herramientas a los profesionales de la salud","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242616,"idioma_id":4,"titulo":"Skin penetration and UV-damage prevention by nanoberries","resumen":"SummaryBackground: Ethanolic extract from blueberry (Vaccinium myrtillus) is rich inanthocyanins and thus exhibits antioxidant activity. On the other hand, ultradeformable liposomes are capable of penetrating to the impermeable barrier of skin. Nanoberries are ultradeformable liposomes carrying blueberry extract.Objectives: In this study, their capacity to penetrate the stratum corneum and photodamage prevention were tested, with the aim of developing a topical formulation for skin protection from environmental damage.Methods: Nanoberries were prepared by lipid film resuspension with ethanolicextract from blueberry, followed by sonication and incorporation to a gel. Size, zeta potential, deformability, rheology, and viscoelasticity were determined. Toxicity was assessed in vivo in zebrafish model, while in vitro cytotoxicity assay was performed on HaCaT and HEK-293T cell lines. Skin penetration was evaluated with the Saarbr?ucken penetration model followed by tape stripping, cryosection, or optical sectioning. UV-damage protection and photoprotection were determined by ad hoc methods with UVA, UVB, and UVC radiation on HaCaT cells. Wound assay was performed on HaCaT cells.Results: Nanoberries of about 100 nm, with differential elastic properties, did penetrate the stratum corneum, with low toxicity. When HaCaT cells were exposed to UV radiation in the presence of nanoberries, their viability was maintained.Conclusions: Nanoberries could be effective to protect the skin from sunphotodamage.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242619,"idioma_id":5,"titulo":"Estudio de prevalencia sobre alcoholismo y factores clínicos asociados en pacientes internados","resumen":"A pesar de que el alcoholismo es un grave problema de salud pública, hay pocos trabajos publicados acerca de incidencia y clínica en instituciones psiquiátricas o en hospitales generales.Objetivos. Determinar la prevalencia del alcoholismo en internados, cuantificar factores clínicos asociados y medir alteraciones clínicas o humorales vinculadas a alcohol o a hepatopatía comparando hallazgos en pacientes con consumo de alcohol y sin él. Material y métodos. Estudio prospectivo, observacional, transversal, analítico. Población: pacientes internados en sala de clínica médica en cinco hospitales. Muestra aleatorizada. Se abordaron 126 pacientes de un total de 160 camas (78,75%) donde los estudiantes de Medicina de la Universidad Nacional de La Matanza realizan sus prácticas de la asignatura Campos Clínicos. Estadística descriptiva e inferencial. Resultados. Edadmedia ± ES 57,54 ± 1,78; intervalo de confianza (IC) del 95%: 54,00; 61,08; mediana ± MAD: 60,50 ± 14,50. Varones, 52,60%. Máximo nivel educativo: primario, 58%; secundario, 38,30%. Mediana de internación, 10 ± 6 días. Mediana de internaciones previas, 3 ± 1. Respecto del estado socioeconómico, pueden cubrir sus necesidades sin problemas, 7,8%; poseen ingreso fijo y estable, peroreducido, 53,90%, y no poseen un ingreso fijo, 38,30%. El motivo de internación está vinculado al alcohol en el 4,90% y a una hepatopatía en el 7,30% (en el 4,90% hay coincidencia). Las patologías asociadas más frecuentes son hipertensión (48,41%), enfermedades respiratorias (37,30%), cardiopatías(34,12%), diabetes (23,01%), infecciones urinarias (17,46%), neoplasias (15,87%), trastornos cognitivos (14,28%), hepatopatías previas (13,49%) e insuficiencias renales (13,49%). El 28,57% consume alcohol habitualmente; el 22,20% lo consumió en el último mes. De los consumidores, el 34% realiza un consumo diario; el 54% lo hace de manera esporádica, y el 12%, los fines desemana. Consumo diario (en gramos): media ± ES 61,29 ± 12,81 (IC 95: 35,63; 88,22); mediana ± MAD 35,00 ± 23,50. El 20,20% maneja vehículos. El 27,80% ha tenido cuadros de abstinencia o borrachera. El 2,30% de las mujeres han tomado alcohol durante el embarazo. Los hallazgos físicos más comunes son edema de miembros inferiores (48,41%), dolor en hipocondrio derecho (20,63%) y hepato o esplenomegalia (25,39%). Pacientes con Hb  60: 21,42%;BT > 2: 9,75%; TP  60: 21,79%; KPTT > 45?: 13,33%; glucemia  110: 53,96%; FAL > 180: 12,96%; albúmina  30: 5,55%. Los hallazgos ecográficos fueron: esteatosis, 23,01%; litiasis, 5,55%; hepatomegalia, 17,46%; esplenomegalia, 23,01%; engrosamiento de la pared vesicular, 29,36%; ascitis, 17,46%, yotros (microlitiasis múltiple, hemangioma, pólipos vesiculares, hígado cirrótico, múltiples imágenes hipodensas), 34,92%. En la población alcohólica se encuentra (con respecto a la no alcohólica) mayor número de internaciones previas (p = 0,04) y más antecedentes de trastornos cognitivos (p = 0,01) y de hepatopatía (p = 0,03); en el examen físico, mayor presencia de edema de miembros inferiores (p = 0,005) y de hepato o esplenomegalia (p = 0,01); en el laboratorio, mayor prevalencia de hepatograma alterado (p = 0,005) y de gamma glutamil transpeptidasa elevada (p = 0,0005) y más hallazgos ecográficos de hígado graso (p = 0,0007), hepatomegalia (p = 0,006), esplenomegalia (p = 0,01) y ascitis (p = 0,0001). Conclusiones. Consume habitualmente el 28,40%. Consumo diario, 34%. Mediana de consumo diario, 35 g. Abstinencia o borrachera, 27,80%. Entre la población alcohólica se encuentra un mayor número de internaciones previas, de trastornos cognitivos y de hepatopatía, edema de miembros inferiores y hepato- o esplenomegalia; en el laboratorio, mayor prevalencia de hepatograma alterado y de gamma glutamil transpeptidasa elevada y más hallazgos ecográficos de hígado graso, hepatomegalia, esplenomegalia y ascitis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242620,"idioma_id":4,"titulo":"Development and evaluation of an automatic software for management zone delineation","resumen":"The lack of availability of user-friendly and automatic software for management zone delineation is limiting the adoption of site-specific management practices. Several procedures for management zone delineation have been proposed, but they commonly require the use of different software, or advanced GIS and statistical skills of users, which limit their adoption. This study proposes a user-friendly and automatic software that would integrate all steps in order to delineate management zones and make prescription files. The software includes importation of different input data layers, re-projection and resizing data in a common grid size. An integrative index was proposed for the selection of the optimal number of zones after clustering analysis. Users are guided by graphical windows showing intermediate results. Also, additional automatic post-processing techniques to improve size, shape and fragmentation of delineated zones are available. The final step allows generation of the ESRI Shapefile required to make variable rate prescriptions by zone with minimal user intervention. The performance of the approach was evaluated for management zone delineation using single and multiple layers of data by comparing with Management Zone Analyst software, and the improvement of the approach in the selection of the optimal number of zones and reducing zone-fragmentation was shown. The software design includes a simple graphical user interface and requires minimal user intervention in order to assist the end-user. The main contribution of this work was the successful development of this automatic user-friendly solution that includes all the necessary steps for management zone delineation and prescription file generation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242621,"idioma_id":4,"titulo":"Long-term stability of compression-molded soybean protein concentrate films stored under specific conditions","resumen":"Post-processing evolution of the functional properties of soybean protein concentrate (SPC) films, plasticized with varying levels of glycerol and processed by compression molding, was examined over a period of 90 days. Films stored in the glassy state (25±2°C and 65±2% relative humidity) lost glycerol and water over time, as determined by gas chromatography and the decline in moisture content. SPC films plasticized with 40-50% glycerol showed a time-dependent increment of the elastic modulus and the tensile strength. In turn, the elongation, barrier properties, soluble mass and opacity of these films varied marginally with time. By contrast, films with 30% glycerol lost the most moisture and their elongation was reduced significantly, while water vapor permeability slightly increased with aging. The performance of aged films resulted from the balance between plasticizer and water loss, and the progressive replacement of unordered structures by intermolecular hydrogen bonded &#946;-sheets and aggregates.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242622,"idioma_id":4,"titulo":"BISMUTH (III) SULFIDE AS ADDITIVE:  TOWARDS BETTER LUBRICITY WITHOUT TOXICITY","resumen":"Purpose: to design a fluid formulation with good lubricant properties by using an eviromentally friendly additive for: i) high and low contact pressure conditions; ii) steel\/steel and polymer\/steel systems.Design\/methodology\/approach: bismuth (III) sulfide (Bi2S3, ?green chemistry? synthesis) was added to a commercial vinyl-terminated silicone fluid (PDMS-Vi) to obtain different wt% mixtures. Tribological performance of formulations was studied from Reichert´s tests (steel\/steel system) and block on rign tests (polymer\/steel). The results were compared with formulations prepared with molybdenum (IV) sulfide (MoS2) and graphite.Findings: an orthorrombic crystal lattice (DRX) and a high-purity product (FRX) was evidenced for Bi2S3. Lubricant properties increase when wt% of Bi2S3 increases in formulations. Wear area decreases up to 90% according to Reichert´s tests. Bi2S3 shows a better tribological behavior when compared to MoS2 and graphite.Originality\/value: replacement of lead derivatives by an enviromentally friendly lubricant in EP formulations. Excellent performance compared to commercially used additives.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242625,"idioma_id":5,"titulo":"Las luchas de la migración en contextos laborales: la experiencia de sindicalización de una trabajadora doméstica peruana en Córdoba, Argentina","resumen":"Este artículo se propone reconstruir la experiencia de sindicalización de una trabajadora doméstica peruana en la ciudad de Córdoba (Argentina), indagando acerca de los procesos de subjetividad y resistencia a través de los cuales se transforma en un sujeto que activa el derecho a reivindicar derechos. Asumiendo el desafío de captar la especificidad de las migraciones globales contemporáneas, esta investigación analiza ?desde una estrategia metodológicacualitativa? una historia de vida, con el objetivo de arrojar luz sobre las luchas de la migración cuyas reivindicaciones no pasan por la condición Migratoria ni la cuestión jurídica, sino por el trabajo y los derechos laborales. Para ello, se nutre principalmente de dos perspectivas teóricas:la autonomía de las migraciones y la perspectiva interseccional. Nuestro argumento parte de concebir que la sindicalización que exploramos en este artículo ?entendida en clave de ?lucha? y vinculada a un aspecto fundamental de la subjetividad migrante como es el trabajo?, se halla condicionada fundamentalmente por la intersección de las identificaciones de género, clase social y edad en el curso de vida.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242626,"idioma_id":5,"titulo":"Peruanos en Córdoba: migraciones, talleres textiles y prácticas comunitarias","resumen":"A partir de los resultados de un trabajo de campo etnográfico, este artículo sepropone indagar en las trayectorias laborales en talleres textiles ?informales? de migrantes peruanos que viven en territorios de relegación urbana de Córdoba (Argentina), en el marco de las estrategias de acceso a la ciudad y de reproducción familiar. Asimismo, reflexiona sobre las prácticas comunitarias, en tanto recursos de organización barrial tendientes a la autogestión, que se despliegan en esos territorios en relación con el desarrollo de los tallerestextiles. Este estudio muestra cómo ciertos procesos que exceden la migración en sí misma ?como la presencia\/ausencia del Estado, las redes de trabajo informal y la dificultad para el acceso a la vivienda? se relacionan con las movilidades e inserciones laborales de la población migrante de forma tal que posibilitan y estimulan la existencia y proliferación de tallerestextiles informales en zonas concretas de la ciudad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242627,"idioma_id":5,"titulo":"Efecto de la aplicación de eCG antes o después de la IATF sobre la tasa de preñez en vacas Holstein mestizas en la Amazonía Ecuatoriana","resumen":"El objetivo fue evaluar el efecto de la aplicación de eCG  antes o después de la IATF sobre el folículo preovulatorio, cuerpo lúteo y tasa de preñez. Se utilizaron 122 vacas Holstein en cuatro experimentos, Tratamiento A (TA): no se aplica eCG en ningún momento de la terapia hormonal, Tratamiento B (TB): eCG al finalizar un tratamiento con progesterona y estradiol para IATF, Tratamiento C (TC): eCG al día 14 luego de la IATF y Tratamiento D (TD): eCG previo a la ovulación y 14 días luego de la IATF. De las 29 vacas utilizadas en el TA se preñaron el 62%, con el TB se preñaron 49%, con el TC se preñaron el 46%  y con el TD se preñaron el 60% de las vacas (X2 =1,56) p&#8805;0,4573. Se concluye que no existieron diferencias entre los diferentes tratamientos sobre el efecto  del folículo preovulatorio, cuerpo lúteo y tasa de preñez.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242628,"idioma_id":5,"titulo":"Potentia Dei y su concurso en el mundo natural según Juan Duns Escoto","resumen":"&lt;!-- \/* Font Definitions *\/@font-face{font-family:'&#65325;&#65331; &#26126;&#26397;';panose-1:0 0 0 0 0 0 0 0 0 0;mso-font-charset:128;mso-generic-font-family:roman;mso-font-format:other;mso-font-pitch:fixed;mso-font-signature:1 134676480 16 0 131072 0;}@font-face{font-family:'Cambria Math';panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:-536870145 1107305727 0 0 415 0;}@font-face{font-family:Cambria;panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:-536870145 1073743103 0 0 415 0;} \/* Style Definitions *\/p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-unhide:no;mso-style-qformat:yes;mso-style-parent:'';margin:0cm;margin-bottom:.0001pt;text-align:justify;text-justify:inter-ideograph;mso-pagination:widow-orphan;font-size:12.0pt;font-family:'Times New Roman';mso-fareast-font-family:'&#65325;&#65331; &#26126;&#26397;';mso-fareast-language:JA;}.MsoChpDefault{mso-style-type:export-only;mso-default-props:yes;font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:Cambria;mso-ascii-font-family:Cambria;mso-fareast-font-family:'&#65325;&#65331; &#26126;&#26397;';mso-hansi-font-family:Cambria;}@page WordSection1{size:612.0pt 792.0pt;margin:72.0pt 90.0pt 72.0pt 90.0pt;mso-header-margin:36.0pt;mso-footer-margin:36.0pt;mso-paper-source:0;}div.WordSection1{page:WordSection1;}--&gt;Juan Duns Escoto configura supensamiento filosófico desde una perspectiva cristiana, marcado por la accióndivina omnipotente que crea y conserva las creaturas. Toda obra del creador ad extra es contingente, de tal maneraque la realidad física recibe esa característica a nivel ontológico yoperativo. El presente trabajo tiene como objetivos determinar el alcance y lamodalidad en que actúa la potentia Deisobre el mundo natural según el Doctor Sutil y resolver una posibleinconsistencia en su pensamiento cuando analiza la capacidad del homo viator para alcanzar certeza en elconocimiento experimental.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242629,"idioma_id":4,"titulo":"Geographic variation of Serjania perulacea (Paullinieae, Sapindaceae) and description of two new varieties","resumen":"We assessed the morphological diversity of Serjania perulacea using multivariate analyses (principal coordinates and component analysis) of quantitative and qualitative morphological leaf traits. We also investigated the effect of local environmental conditions on the distribution of the different phenotypes. Our results indicate that S. perulacea consists of three varieties, which are restricted to specific geographic areas with distinct environmental conditions. The two new varieties S. perulacea var. krapovickasii and S. perulacea var. chacoensis are described here and a lectotype for the autonymic variety isdesignated. An identification key, illustrations and distribution maps for all three varieties are also provided.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242631,"idioma_id":4,"titulo":"Genetic diversity of Mycobacterium avium complex strains isolated in Argentina by MIRU-VNTR","resumen":"Mycobacterium avium sp. avium (MAA), M. avium sp. hominissuis (MAH), and M. avium sp. paratuberculosis (MAP) are the main members of the M. avium complex (MAC) causing diseases in several hosts. The aim of this study was to describe the genetic diversity of MAC isolated from different hosts. Twenty-six MAH and 61 MAP isolates were recovered from humans and cattle, respectively. GenoType CM® and IS1311-PCR were used to identify Mycobacterium species. The IS901-PCR was used to differentiate between MAH and MAA, while IS900-PCR was used to identify MAP. Genotyping was performed using a mycobacterial interspersed repetitive-unit-variable-number tandem-repeat (MIRU-VNTR) scheme (loci: 292, X3, 25, 47, 3, 7, 10, 32) and patterns (INMV) were assigned according to the MAC-INMV database (http:\/\/mac-inmv.tours.inra.fr\/). Twenty-two (22\/26, 84·6%) MAH isolates were genotyped and 16 were grouped into the following, INMV 92, INMV 121, INMV 97, INMV 103, INMV 50, and INMV 40. The loci X3 and 25 showed the largest diversity (D: 0·5844), and the global discriminatory index (Hunter and Gaston discriminatory index, HGDI) was 0·9300. MAP (100%) isolates were grouped into INMV 1, INMV 2, INMV 11, INMV 8, and INMV 5. The HGDI was 0·6984 and loci 292 and 7 had the largest D (0·6980 and 0·5050). MAH presented a higher D when compared with MAP. The MIRU-VNTR was a useful tool to describe the genetic diversity of both MAH and MAP as well as to identify six new MAH patterns that were conveniently reported to the MAC-INMV database. It was also demonstrated that, in the geographical region studied, human MAC cases were produced by MAH as there was no MAA found among the human clinical samples.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242632,"idioma_id":5,"titulo":"Relevancia clínica, diversidad y variabilidad genética de distintas especies del genero Mycobacterium","resumen":"Introducción: El término micobacterias no tuberculosas (MNT) incluye distintas especies ambientales capaces de enfermar humanosy\/o animales incluso mediante una probable transmisión zoonóticaObjetivos. Determinar: la importancia clínica de varias especies del género Mycobacterium y la diversidad genética del Complejo M. avium (MAC), la sensibilidad bacteriana in vitro yel éxito del tratamiento especifico.Materiales y Métodos: Recolección de datos clínicos, epidemiológicos y aislamientos en el periodo 2009-2016; identificación molecular de los aislamientos; determinación de la sensibilidad bacteriana in vitro y de la diversidad genética del MAC; evaluación del tratamiento.Resultados: Fueron diagnosticados 225 casos de micobacteriosis, con prevalenciaestable &#8776; 6% por año, y 22 especies recuperadas: 4 de rápido desarrollo aisladas de 66pacientes y 18 de lento desarrollo. MAC fue aislado en 95 casos, 40 M. avium hominissuis,51 M. intracellulare, 3 M. chimaera, 1 M. colombiense. Se observó mayor probabilidad de enfermar por M. intracellulare en pacientes tratados previamente por tuberculosis (TB).Los pacientes HIV+ tuvieron riesgo incrementado de enfermedad causada por M. avium hominissuis. Los aminoglucósidos, fluoroquinolonas y macrólidos fueron las drogas más activas frente a la mayoría de las MNT. Aproximadamente la mitad de los casos curaron.Conclusiones: M. intracellulare, M. aviumhominissuis con una gran variabilidad genética, y M. abscessus fueron los patógenos más frecuentemente hallados. Un hallazgo importante fue el de casos de enfermedad mixta TB+MNT. Estos pacientes requirieron una terapia con agregado de drogas de segunda línea al esquema terapéutico para TB habiendo curado la mayoría de ellos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242636,"idioma_id":5,"titulo":"EVALUACION DE UN PROTOTIPO DE CONCENTRADOR SOLAR TÉRMICO DE REFLECTOR LINEAL FIJO","resumen":"Apartir de los resultados de estudios geométricos previos se construyó unprototipo de concentrador solar térmico de reflector lineal fijo y absorbedormóvil. Se realizó un análisis teórico para la determinación de los parámetrosinvolucrados en los intercambios energéticos y se confeccionó un modelo delsistema. Se evaluó experimentalmente el prototipo bajo distintas condiciones defuncionamiento. Se elaboró la simulación térmica del sistema la cual fuevalidada con datos medidos. Se logró un buen funcionamiento del mecanismo deseguimiento solar y el correcto enfoque de la radiación sobre el absorbedor. Seanalizó la eficiencia óptica del equipo y se proponen modificaciones en eldiseño para futuros trabajos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242637,"idioma_id":4,"titulo":"Quantum chemical and kinetic study of the CCl 2 self-recombination reaction","resumen":"The temperature and pressure dependencies of the rate constants of the recombination reaction CCl2 + CCl2 + M &#61614; C2Cl4 + M have been theoretically studied between 300 and 2000 K. Quantum-chemical calculations were employed to characterize relevant parts of the potential energy surface of this process. The limiting rate constants were analyzed using the unimolecular reaction theory. The resulting low pressure rate constants can be represented as k0 = &#61531;Ar&#61533; 3.46 x 10-23 (T\/300 K)-8.68 exp(-1600 K\/T) cm3 molecule-1 s-1. The high pressure rate constants derived from statistical adiabatic channel model\/classical trajectory calculations is k&#61605; = (5.0 ± 3.0) x 10-13 (T \/ 300)0.7±0.1 cm3 molecule-1 s-1. The falloff curves were represented in terms of these limiting rate constants. Reported experimental results are satisfactorily described with the present model. The calculations indicate that the CCl2 + CCl2 reaction proceeds via the stabilization of C2Cl4, with a contribution of the C2Cl3 + Cl &#61614; C2Cl4 reaction, and at sufficiently high temperatures the channel CCl2 + CCl2 &#61614; C2Cl2 + 2 Cl becomes relevant.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242638,"idioma_id":4,"titulo":"Silicon isotope separation by two frequency IRMPD","resumen":"InfraRed Multi-Photon Dissociation (IRMPD) is a highly selective laser isotope separation technique. This process consists of a sequential IR photon absorption from the ground vibrational state up to dissociation by a molecule that contains the isotope of interest. High dissociation threshold molecules require large intensity radiation fields. This drawback could be overcome by two-frequency IRMPD. In this technique, a low energy laser resonant with the first energy levels guarantees isotopic selectivity excitation and a second non-resonant large energy laser achieves molecular dissociation. The possibility of obtaining silicon laser isotopic enrichment using SiF4 as working molecule was investigated in this work. Two-frequency IRMPD of SiF4 with two TEA CO2 single transverse mode lasers was studied in a molecular jet. The dissociation process was monitored with a Time-of-Flight mass spectrometer with UV multi-photon ionization. The excitation laser fluence and wavelength dependence of the isotopic dissociation estimator, &#945;, and the enrichment factor estimator, &#946;, were determined and compared to those obtained in single-frequency IRMPD.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242640,"idioma_id":5,"titulo":"Lacan, la autonomía de lo simbólico y los límites de su trascendencia","resumen":"En este artículo propongo rastrear la conceptualización que realiza Jacques Lacan del registro simbólico durante la década del ?50, como posible aporte del psicoanálisis a las ciencias sociales. La estrategia metodológica es una lectura centrada en El Seminario sobre la carta robada (1956), pero atenta a las resonancias que dicho texto guarda con otros de sus escritos clave de aquella década.En el trabajo destaco la ambivalencia que envuelve el pensamiento de Lacan en torno a la noción de orden simbólico. La afirmación de la autonomía de lo simbólico permite a Lacan abrir una alternativa a las concepciones esencialistas de la subjetividad, pero lo expone a sus propios riesgos teóricos, como es la posibilidad de reintroducir un nuevo principio de trascendencia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242643,"idioma_id":4,"titulo":"Polymer nanoparticles containing essential oils: new options for mosquito control","resumen":"Mosquitoes (Diptera: Culicidae) are vectors of important parasites and pathogens causing death, poverty and social disability worldwide. The overuse of synthetic insecticides to control mosquito vectors lead to resistance, adverse environmental effects and high operational costs. Therefore, the development of eco-friendly control tools is an important public health challenge. In this study, two different essential oils (EO) (geranium, Geranium maculatum, and bergamot, Citrus bergamia) loaded polymeric nanoparticle (PN) were elaborated using polyethylene glycol (PEG) and chitosan (Qx) as the polymeric matrix\/coating. In addition, the mosquito larvicidal acute and residual activity of the PN was evaluated on Culex pipiens pipiens. The physicochemical characterization of PN revealed that PEG-PN had sizes <255 nm and encapsulation efficiency between 68 and 77%; Qx-PN showed sizes <535 nm and encapsulation efficiency between 22 and 38%. From the toxicological test, it was observed that Qx-PN produced higher acute and residual activity than PEG-PN. Overall, this study highlights that polymer nanoparticles containing essential oil are a promising source of eco-friendly mosquito larvicidal products.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242644,"idioma_id":4,"titulo":"Efficacy of essential oils to control the Indian meal moth, Plodia interpunctella (H&uuml;bner) (Lepidoptera: Pyralidae)","resumen":"Essential oils (EOs) have been recognized as an important source of biopesticides. This work investigated the chemical constituents and bioactivity of six essential oils namely lavender (Lavandula angustifolia Mill.), peppermint (Mentha piperita L.), geranium (Geranium maculatum L.), palmarosa (Cymbopogon martinii (Roxb.) Wats), eucalyptus (Eucalyptus globulus Labill.) and bergamot (Citrus bergamia Risso) against adults of the Indian meal moth, Plodia interpunctella, a cosmopolitan pest that infests a wide range of stored products. Analysis by gas chromatography coupled to mass spectrometry (GC?MS) revealed the presence of several compounds, mainly mono- and sesquiterpenes. The contact toxicity assay showed that the EO from palmarosa was the most toxic with a LD50 value of 22.8 &#956;g cm&#8722; 2. The toxicity order was palmarosa > geranium > peppermint > lavender > bergamot > eucalyptus. In fumigant toxicity assay, the greatest effect was found with the EO from eucalyptus with a KT50 value of 8.34 min. The toxicity order was eucalyptus > peppermint > geranium = lavender > bergamot > palmarosa. The EO from palmarosa showed the highest residual activity when the insects were exposure to its volatiles constituents. Finally, all EOs produce sublethal activity promoting effects in the fecundity. In conclusion, the EOs could be used as potential biopesticides for P. interpunctella control.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242645,"idioma_id":5,"titulo":"Educación y desigualdad. Un repaso por algunos aportes de la sociología de la educación en Argentina.","resumen":"El artículo plantea un recorrido histórico que permite reconocer el desarrollo que el sistema educativo ha tenido, marcando su heterogeneización, en paralelo al proceso de progresiva diferenciación social. Apela a tres conceptos: segmentación, fragmentación y segregación educativas, para dar cuenta de las modalidades en que se produce y reproduce la desigualdad en el sistema educativo. Sin negar la incidencia que la escolarización tiene, en ciertos contextos y condiciones, para mejorar la dimensión material de vida de los sectores más pobres de la población, se enfatiza que la eficacia real que la educación implique en términos de reducción de la pobreza y la disminución de la desigualdad social dependen del contexto socioeconómico en que se desarrolle.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242649,"idioma_id":4,"titulo":"Introduction: problematizing voice and representation in youth media production","resumen":"This introduction to the special issue Voice and representation in youthmedia production in educational settings: transnational dialogues presentsa discussion of the notions of voice and representation and an overviewof the contributions to this issue, and reflects on the possibilities andlimits for a transnational dialogue within current academic traditions andpublishing practices.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242650,"idioma_id":5,"titulo":"La iconoclastia en el cine y la pedagogía. Reflexiones a propósito de dos películas infantiles de los años ?30","resumen":"A iconoclastia é uma parte da história das imagens em educação que considera sentidos múltiplos. Nas muitase intensas paixões provocadas pelas imagens, destaca-se a iconoclastia como um sentimento forte que conferemuitos poderes às imagens ? uma reverência e um medo que leva ao ponto de destruí-las. Porém, aiconoclastia tem sido pouco estudada na história da educação. Neste artigo, proponho uma primeiraaproximação entre a iconoclastia e a história da educação por meio da análise de dois filmes dos anos 1930sobre crianças, Emil und die Detektive (Alemanha, Gerhard Lamprecht, 1931) e Zéro de conduite (França, JeanVigo, 1933), que contêm várias cenas nas quais monumentos e outros ícones das autoridades tradicionais sãoprofanados. A partir desses filmes, reflito sobre a ambivalência do gesto iconoclasta, como uma história darevolta contra as autoridades constituídas, mais também como um movimento que permanece em um círculode ?fascinação, repulsão, destruição, expiação... gerado pela adoração da imagem proibida? (LATOUR, 2010,p.70), um círculo a ser questionado se pretendemos abrir caminho para uma outra política do visual.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242651,"idioma_id":4,"titulo":"Iconoclastic images in the history of education. Another look at children in revolt in two children?s films from the 1930s","resumen":"There are images in the history of education that can be considerediconic, images that are, as Georges Didi-Huberman says, ?full offuture?. In this article, I want to consider two children?s films from the1930s, Emil und die Detektive (Gerhard Lamprecht, Germany, 1931)and Zéro de conduite (Jean Vigo, France, 1933) that include severalscenes portraying children in revolt against traditional authorities.Whereas the hitherto dominant visual imaginaries about childhoodstressed children?s innocence, these films depict images that showchildren as subjects of political, collective actions, in line with thepolitical mobilisation of those years. These images can be definedas iconoclastic in their explicit break or rupture with the icons ofauthority (teachers, statues, policemen, school buildings); in fact,film itself has been considered an iconoclast medium because of itsadoption of movement against contemplation, and of the practicesof fragmentation and montage that it imposes on the image. In myapproach, I argue for the relevance of visual studies to the historyof education, and particularly for the consideration of iconophiliaand iconoclasm as particular politics of the image. The analysis oficonoclasm wants to point to its ambivalence, as the attack on imagesimplies at the same time the production of new icons that becomeidolatrised and romanticised. In the case here considered, the image ofchildren in revolt has become one of these new icons, which openeda space for desire and hope for a new world but whose politics maystill need further interrogation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242652,"idioma_id":4,"titulo":"INHIBITION OF AN EXTRACELLULAR POLYGALACTURONASE FROM GEOTRICHUM CANDIDUM BY A PROTEINACEOUS INHIBITOR ISOLATED FROM LEMON FRUITS","resumen":"An extracellular polygalacturonase [EC 3.2.1.15], named PG-543, was purified from the culture of Geotrichum candidum IEV 543, a phytopathogenic fungi isolated from infected lemon. The molecular mass of the enzyme was estimated to be 26 kDa by SDS-PAGE. The pH optimum determined was 5.5; the enzyme showed high stability in the pH range between 4.0 and 6.0. The temperature optimum was 37 ºC. Furthermore, a proteinaceous inhibitor of the polygalacturonase (PG) named PGIP was isolated from lemon albedo. This protein was able to maintain the inhibitory activity in a wide range of pH and temperature. The maximal interaction between PG-PGIP was reached after 20 min of contact. PGIP did not show toxic effect on Artemia salina in the concentration range that was active on PG enzyme. Also, the proteinaceous inhibitor did not show mutagenic nor phytotoxic effects.  Our results suggest that, the PGIP isolated from lemon could be used as a natural product to decrease the propagation of pathogenic fungi responsible for postharvest diseases in citrus by the inhibition of hydrolytic enzymes secreted by pathogens.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242653,"idioma_id":4,"titulo":"Evaluation of antioxidant and antimutagenic activity of herbal teas from native plants used in traditional medicine in Argentina","resumen":"The Jarilla species are commonly used in Argentinean local communities to heal different ailments and are frequently used as infusions or decoctions. Herbal mixture infusions composed of Zuccagnia punctata Cav. (Zp), Larrea cuneifolia Cav. (Lc), Larrea divaricata Cav. (Ld), also incorporating an exotic plant species Hovenia dulcis Thunb. (H), were developed and the total phenolic and flavonoid content, antioxidant activity and mutagenic\/ antimutagenic capacity were analyzed and compared with the single-plant teas. The phenolic contents ranged from29.5 mg GAE\/l to 1139mg GAE\/l, and the flavonoid contentwas between 20.1 and 62mg EQ\/l. The mixture with higher content of H. dulcis (H mix) infusion showed the highest preference score in a sensory evaluation.Free radical scavenging capacity was determined by the ABTS assay and the most active was the mixture with equal quantities of each plant species (1\/4 mix infusion). None of the plant extracts showed mutagenic effects against Salmonella typhimurium tester strains TA98 and TA100 with and without metabolic activation. The antimutagenic properties against a direct mutagen, 4-nitro-o-phenylendiamine (4-NPD), of three herbal mixtures showed about 30% of inhibition ofmutagenicity. Four phenolic compounds were identified in the infusions prepared with the plant mixtures. The developed beverages in this work could be important dietary sources of antioxidant and antimutagenic compounds for prevention of chronic diseases.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242655,"idioma_id":4,"titulo":"Chemical and functional characterization of skin, pulp and seed powder from the Argentine native fruit mistol ( Ziziphus mistol ). Effects of phenolic fractions on key enzymes involved in metabolic syndrome and oxidative stress","resumen":"The mistol (Ziziphus mistol) is a native food tree occurring in dry areas of Northwestern and Central Argentina. Studies on its functional properties and bioactive compounds are scarce so far. In this work we assess the nutritional and functional components of lyophilized powder of mistol skin, pulp and seed.The powder from the different fruit parts have moderate carbohydrate content and are an important source of flavonoids, fiber, potassium, magnesium and calcium. The HPLC?ESI-MS\/MS analysis of the polyphenols enriched extracts (PEE) of the samples allowed the identification of 17 compounds including  16 flavonoids and a procyanidin. The PEE showed antioxidant capacity and were able to inhibit aglucosidase,a-amylase and pancreatic lipase, enzymes related to metabolic syndrome. The results suggest potential of the lyophilized skin, pulp and seed powder from mistol as functional food or dietary supplement in the prevention or treatment of diseases associated with metabolic syndrome.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242656,"idioma_id":4,"titulo":"The native fruit geoffroea decorticans from arid Northern Chile: Phenolic composition, antioxidant activities and in vitro inhibition of pro-inflammatory and metabolic syndrome-associated enzymes","resumen":"The native tree Geoffroea decorticans (cha ar) grows in the arid lands of northern Chile. It has been used as a food plant since prehistoric times. Phenolic-enriched extracts (PEEs) of Chilean cha ar fruits were assessed for their chemical composition, antioxidant properties and inhibition of pro-inflammatory and metabolic syndrome-associated enzymes. Phenolic profiles were determined by HPLC-DAD-MS\/MS. The PEEs of G. decorticans showed a strong effect towards the enzymes COX-1\/COX-2, with inhibition percentages ranging from inactive to 92.1% and inactive to 76.0% at 50 µg PEE\/mL, respectively. The IC50 values of the PEEs towards lipoxygenase and phospholipase A2 inhibitory activity were between 43.6?96.8 and 98.9?156.0 µg PEE\/mL, respectively. Samples inhibited &#945;-glucosidase (IC50 0.8?7.3 µg PEE\/mL) and lipase (9.9 to 100 µg PEE\/mL). However, samples did not inhibit &#945;-amylase. The HPLC-DAD-MS analysis of the PEEs allowed the tentative identification of 53 compounds, mainly flavonol glycosides and procyanidins. The procyanidin content of the Chilean G. decorticans pulp was positively correlated with the antioxidant activity and the inhibition of the enzyme &#945;-glucosidase. These results indicate that the Chilean cha ar fruit contains bioactive polyphenols with functional properties.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242657,"idioma_id":4,"titulo":"Beneficial effects of hydroalcoholic extract and flavonoids from Zuccagnia punctata in a rabbit model of vascular dysfunction induced by high cholesterol diet","resumen":"This study evaluated the effects of a Zuccagnia punctata standardized hydroalcoholic extract (ZpE) and three of its major flavonoids [2&#8242;,4&#8242;-dihydroxychalcone (DHC), 7-hydroxyflavanone (HF) and 3,7-dihydroxyflavone (DHF)] on the vascular reactivity of aortic rings with endothelial dysfunction induced by feeding rabbits on a high cholesterol diet. Rabbits were fed with either normal chow or a diet containing 1% cholesterol for 5?6 weeks. Isometric contractions were measured. Concentration response curves to ZpE (range from 4 × 10&#8722;2 to 4 × 10 µg gallic acid equivalent\/ml), DHC, DHF or HF (range from 10&#8722;9 to 10&#8722;4 M) showed concentration-dependent relaxation of arteries pre-contracted with phenylephrine. ZpE (4 × 10&#8722;2, 4 × 10&#8722;1 and 4 µg gallic acid equivalent\/ml), HF (10&#8722;9, 10&#8722;7, 10&#8722;5 M), DHC (10&#8722;9 M) and DHF (10&#8722;9 M) added to the bath improved acetylcholine affinity. Pre-treatment of arteries with ZpE (4 × 10&#8722;2 µg gallic acid equivalent\/ml) and DHC (10&#8722;9 M) reduced phenylephrine-induced contraction. Incubation with the higher dose of ZpE (4 µg gallic acid equivalent\/ml) reduced the angiotensin II-maximal contraction (Cmax) acting as a non-competitive antagonist, while DHC and DHF (10&#8722;5 M) caused a non-parallel rightward of the angiotensin II-concentration response curves and reduced the Cmax acting as mixed antagonists. ZpE (4 × 10&#8722;2 µg gallic acid equivalent\/ml), DHC and DHF (10&#8722;9 M) caused a rightward displacement of angiotensin II-concentration response curves acting as competitive antagonists. In conclusion, the present study demonstrated that a ZpE and its major flavonoids had beneficial effects in arteries with vascular dysfunction induced by hypercholesterolemia. Therefore its use as herbal medicine to prevent cardiovascular risks factors may be promising.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242667,"idioma_id":4,"titulo":"Thickness determination of anodic titanium oxide films by electron probe microanalysis","resumen":"Thin film thickness can be readily associated to the X-ray intensities emitted under electron bombardment. The aim of this work is to develop a method for measuring titanium oxide thicknesses in biomaterials from the X-ray spectra induced in a scanning electron microscope. The oxide layers studied were generated with different anodizing voltages applied in phosphoric and boric acid solution (H3PO4\/H3BO3). The oxygen K&#945; intensity was registered for each sample and related to the corresponding thickness. In order to account for local material alterations, a recalibration is shown to be necessary; Rutherford backscattering spectroscopy was used at this stage. The method is useful for TiO2 thicknesses in the range of interest for dental and orthopedic implants (10?100 nm), and it could be extended to greater thicknesses by adequately selecting the electron beam energy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242668,"idioma_id":4,"titulo":"Structure of the Fe and Ni L x-ray spectra A. Sepúlveda, T. Rodríguez, P. Pérez, A. P. L. Bertol, A.C. Carreras, J. Trincavelli, M.A.Z. Vasconcellos, R. Hinrichs y G. Castellano. Journal of Analytical Atomic Spectrometry","resumen":"Fe-L and Ni-L X-ray spectra induced by electron impact were analyzed. The measurements were made on bulk samples using a commercial wavelength dispersive spectrometer, and the spectra were processed with a parameter optimization method previously developed. This procedure allowed for the determination of characteristic energies, relative transition probabilities and natural linewidths. The results obtained are compared to the data found in the literature, when available. Satellite and radiative Auger emissions were also analyzed, energy shifts and relative intensities being determined. Many of these parameters were determined for the first time, which was possible due to the robustness of the spectral processing method used. The line profile introduced here takes into account the differential attenuation at both sides of the absorption edge.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242670,"idioma_id":4,"titulo":"Formation of aerobic granular sludge during the treatment of petrochemical wastewater.","resumen":"In this study, petrochemical wastewater from the port of Antwerp was used for the development of aerobic granular sludge. Two different reactor setups were used, (1) a completely aerated sequencing batch reactor (SBRae) with a feast\/famine regime and (2) a sequencing batch reactor operated with an anaerobic feast\/aerobic famine strategy (SBRan). The seed sludge showed poor settling characteristics with a sludge volume index (SVI) of 285mL.gMLSS-1 and a median particle size by volume of 86.0µm±1.9µm. In both reactors, granulation was reached after 30days with a SVI of 71mL.gMLSS-1 and median granule size of 264.7µm in SBRan and a SVI of 56mL.gMLSS-1 and median granule size of 307.4µm in SBRae. The chemical oxygen demand (COD) and dissolved organic carbon (DOC) removal was similar in both reactors and above 95%. The anaerobic DOC uptake increased from 0.13% to 43.2% in 60days in SBRan.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242671,"idioma_id":4,"titulo":"Aeration control strategies to stimulate simultaneous nitrification-denitrification via nitrite during the formation of aerobic granular sludge","resumen":"In this study, a sequencing batch reactor (SBR), treating synthetic wastewater (COD\/N&nbsp;=&nbsp;5), was operated in two stages. During stage I, an aeration control strategy based on oxygen uptake rate (OUR) was applied, to accomplish nitrogen removal via nitrite &gt;80%. In stage II, the development of aerobic granular sludge (AGS) was examined while two aeration control strategies (OUR and pH slope) maintained the nitrite pathway and optimized the simultaneous nitrification-denitrification (SND) performance. Stimulation of slow-growing organisms, (denitrifying) polyphosphate-accumulating organisms (D)PAO and (denitrifying) glycogen-accumulating organisms (D)GAO leads to full granulation (at day 200, SVI10&nbsp;=&nbsp;47.0&nbsp;mL\/g and SVI30&nbsp;=&nbsp;43.1&nbsp;mL\/g). The average biological nutrient removal efficiencies, for nitrogen and phosphorus, were 94.6 and 83.7%, respectively. Furthermore, the benefits of an increased dissolved oxygen concentration (1.0-2.0&nbsp;mg&nbsp;O2\/L) were shown as biomass concentrations increased with approximately 2&nbsp;g\/L, and specific ammonium removal rate and phosphorus uptake rate increased with 33 and 44%, respectively. It was shown that the combination of both aeration phase-length control strategies provided an innovative method to achieve SND via nitrite in AGS.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242672,"idioma_id":4,"titulo":"Molecular characterization of diarrheagenic Escherichia coli isolated from vegetables in Argentina","resumen":"The aim of this study was to investigate the prevalence of diarrheagenic E. coli strains in vegetables from the humid Pampa region, Argentina, and to determine the occurrence of serotypes and virulence genes in the isolates.A total of 373 fresh vegetable samples obtained from 41 different geographical points were examined. E. coli was detected in 38.6% of the samples. Ten isolates could be obtained from 14 samples presumptively positive for diarrheagenic E. coli: 8 were identified as atypical Enteropathogenic E. coli (aEPEC) and 2 as Verocytotoxigenic E. coli (VTEC). Lettuce and beet were the vegetables most frequently contaminated with pathogenic E. coli. The isolates belonged to serotypes O1:H7, O28:H19, O39:H40, O86:H31, O132:H8, O139:H20, O178:H7 and O178:H19, some of which reportedly have caused human illness, and one isolate resulted non typeable. Taking into account the distribution of 16 nle genes, 7 profiles were detected. On the other hand, all tested isolates harbored the gene encoding for the adhesin HcpA. Other adhesion related genes were also identified: ecpA and elfA were detected in 90%, lpfA0113 in 60%, and ehaA in 50% of the isolates meanwhile ihaA was only observed in O178:H19 isolate. This VTEC isolate harbored, also, Cdt-V toxin and megaplasmid encoding genes such as espP, subA and epeA and exhibited a strong cytotoxic effect. These data is the first molecular E. coli report that confirms the presence of E. coli pathotypes circulating among vegetables in Argentina. Genetic characterization showed that in addition to eae or vtx genes, isolates obtained from vegetablesharbored genes encoding other toxins, adhesins, and components related to the type III secretion system that could contribute to their virulence. In conclusion, this research shows that vegetables in Argentina may bethe source of VTEC and EPEC infections in the community and therefore, they should be considered as vehicles for transmission of these potentially pathogenic bacteria.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242673,"idioma_id":4,"titulo":"Virulence traits and differentnle profiles in cattle and human verotoxin-producing Escherichia coli O157:H7 strains from Argentina.","resumen":"Verotoxin-producing E. coli (VTEC) O157:H7 is the dominant serotype isolated from patients with HUS and, Argentina has the highest rate of HUS in the world. Molecular typing had allowed to identify subpopulations related to the origin and virulence of O157:H7 strains. Our aim was to perform a genetic characterization of 43 O157:H7 strains isolated in Argentine mostly from cattle and humans in order to establish the potential public health risk. For it, we used a combination of molecular subtyping methods in order to identify clade 8_rhsA (C3468G), LSPA-6 and virulence profiles and, a cytotoxicity assay on Vero cell. All isolates carried the clade 8 SNP variant and 98% of them belonged to lineage I\/II (2% lineage II). Isolates were grouped into eleven nle profiles, 46% were positive for all nle genes, while the remaining isolates, except two, showed incomplete OI-71, particularly lacked nleF. All isolates showed the plasmid profile ehxA-espP-katP-stcE and harbored ehaA, elfA, iha and lpfA variants lpfA1-3 and lpfA2-2 and, ECSP_0242. The frequencies of the remaining ECSP genes were 95% ECSP_2687, 88% ECSP_3286, 86% ECSP_3620, 53% ECSP_2870\/2872 and 44% ECSP_1733. All O157:H7 strains, except the isolate identified as lineage II, were cytotoxic on Vero cells. Among Argentinean strains, most genetic markers occur at equal relative frequencies among clinical and bovine isolates, showing diversity mostly in nle genes profiles. The belonging of the isolates to hypervirulent clade 8 and lineage I\/II, the high prevalence of nle and putative virulence factors genes, would allow assigning most O157:H7 strains of this region a high risk to public health.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242674,"idioma_id":5,"titulo":"Vision bioetica en los avances esteticos y los requerimientos del hombre hoy","resumen":"La creciente demanda de estética por parte de los pacientes y el avance tecnocientífico actual de las ciencias de la salud exigen una reflexión profunda de la estética como valor.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242676,"idioma_id":5,"titulo":"Semillas de colza y cebada: estrategias de mejoramiento y comercialización de nuevos cultivares en Argentina (2004-2014)","resumen":"Desde una perspectiva sistémica y constructivista, el trabajo analiza el mercado de semillas de colza y cebada de los principales criaderos de semillas en Argentina desde el año 2004 al 2014. El estudio enfatiza en los cambios de la producción nacional de colza y cebada, la concentración y tendencias del mercado de semillas de ambas especies, los procesos de articulación y coordinación de mercado, los mecanismos de retribución a los derechos de propiedad intelectual y el rol de los sistemas nacionales de ciencia y técnica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242678,"idioma_id":4,"titulo":"Silver nanoparticles from leafy green extract of Belgian endive (Cichorium intybus L. var. sativus): Biosynthesis, characterization, and antibacterial activity","resumen":"We report for the first time a green, simple, and low-cost synthesis of silver nanoparticles (AgNPs) by mixing AgNO3 solution with the aqueous leaf extract of Belgian endive, a variety of Cichorium intybus L., without any harmful reducing and capping agents. The biosynthesis of AgNPs was observed by the color charge from colorless (metal salt solution) to a yellowish brown (nanoparticle colloidal dispersion), which was confirmed by UV?vis spectroscopy, transmission electron microscopy (TEM), and X-ray diffraction (XRD). UV?vis spectra showed the surface plasmon resonance signature of AgNPs around 420 nm, TEM revealed that nanoparticles were quasi-spherical with an average diameter ranging from 19 to 64 nm depending on the metal salt concentration, and XRD pattern indicated that the biosynthetic process produced face-centered cubic AgNPs. Surface-enhanced Raman spectroscopy analysis showed that the AgNPs were capped with bioactive molecules from the leaf extract, which are also believed to be responsible for the bio-reduction of silver ions. The antibacterial activity of the biosynthesized AgNPs was studied using both the disk diffusion and minimum inhibitory concentration methods against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa, and they were found to be effective at picomolar concentration levels.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242679,"idioma_id":5,"titulo":"Mansilla y Darío entre postales: ¿celebridad o esnobismo?","resumen":"Las postales autografiadas generan un circuito de intercambio entre autor y lectores, donde lo que se valora es la firma emancipada de los textos que le otorgaron renombre. Comúnmente atesoradas en álbumes, las postales firmadas acercan la experiencia del autor-productor a la del lector-consumidor y hacen propio un capital (simbólico) ajeno. Desde sus cualidades letradas (de práctica de la escritura, identidad y propiedad) el yo que firma puede otorgar el don de la dedicatoria. Revisamos la ocurrencia de esta práctica en el caso de Mansilla y Darío y las concepciones que ambos enuncian sobre el tema para reflexionar sobre moda, esnobismo y escritura en el pasaje entre el siglo XIX y el siglo XX. A partir de un detalle como el de las postales autografiadas, pensamos al esnobismo en contextos de masificación o ampliación de públicos como el trayecto inesperado que va de la distinción elitista de los escritores en París a la lectura de la prensa periódica en los bares o las esquinas de la ciudad americana moderna. Aunque incómodos frente al fenómeno, Mansilla y Darío intuyeron la creciente disolución entre culturas alta y baja. Cuestionaron con su práctica (aunque no siempre en su discursividad explícita) la separación entre formas aristocratizantes y populares. Como fervorosos renovadores del español americano, adoptaron cómodamente la posición de quien distribuye legitimidades y diseña nuevos gustos. Pero junto a esa distinción, crearon nuevos públicos y expandieron el consumo de objetos culturales. Proponemos pensar la relación contradictoria entre distinción y popularidad, y a ambos autores como figuras oscilantes: refractarias, pero también tentadas hacia formas de lo esnob, como derivación multiplicada de lo dandi.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242680,"idioma_id":5,"titulo":"Evaluación del estado de Salud Bucal de niños de 4 y 5 años que asisten al Centro de Desarrollo Infantil Mitai Roga N° V, de la ciudad de Corrientes Capital","resumen":"La caries en la infancia temprana es una forma particularmente de caries que afecta a los niños más pequeños y que puede causar grandes estragos en la dentición de los infantes en un periodo particularmente corto. Materiales y Métodos se realizó un estudio descriptivo, longitudinal en niños entre 4 y 5 años de ambos sexos. El objetivo fue evaluar el estado de Salud Bucal en niños de 4 y 5 años que asistieron al Centro de Desarrollo Infantil Mitai Roga N° V y las representaciones de madres y maestras sobre Salud Bucal. Se confeccionaron Historias clínicas, Índices ceod y O´Leary inicial. Se llevó a cabo el Programa, posteriormente se tomaron los Índices ceod y O?Leary final. Se realizaron entrevistas profundas a madres y maestras, las que se encuentran en etapa de análisis para determinar las representaciones sociales sobre Salud bucal.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242681,"idioma_id":5,"titulo":"ZOOARQUEOLOGÍA DEL SITIO BARRANCA I (DEPARTAMENTO DE RÍO CUARTO, CÓRDOBA) DURANTE EL HOLOCENO TARDÍO: ANÁLISIS PRELIMINAR","resumen":"En este trabajo se muestran los resultados preliminares en el análisis arqueofaunístico del sitio Barranca I (Pedanía San Bartolomé, Departamento de Río Cuarto, Córdoba) realizado sobre los materiales recolectados hasta la última campaña de diciembre del año 2016. El registro del sitio muestra una baja cantidad de materiales óseos para la dimensión espacial excavada. Un alto porcentaje de estos materiales faunísticos presenta marcas y huellas antrópicas que lo posiciona como un conjunto utilizado por los grupos humanos que habitaron el sitio durante el Holoceno tardío.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242686,"idioma_id":5,"titulo":"Revisión bibliográfica sobre sustentabilidad y ética: implicancias en las organizaciones y actores relevantes","resumen":"La claridad respecto de lo que implica el paradigma de la sustentabilidad para las organizaciones, desde una mirada transdisciplinar, ayuda no sólo a rever la idea que se aborda desde el management respecto del término, sino también a plantearse cuál es el rol que tienen los diversos actores en el entramado de los sistemas socioecológicos, para poder así distinguir los actores de la sustentabilidad.La ética en general y sus réplicas en el management, a través de conceptos como la ética empresarial o ética en los negocios, se considera un instrumento válido de análisis y de interpretación de la perspectiva social de una organización en el marco de la sustentabilidad. Muchos autores del management y de otras disciplinas ya han trabajado la relación entre sustentabilidad y ética, pero resulta importante integrarla con lo social y lo ambiental cuando hablamos de un abordaje transdisciplinar del tema y de su injerencia en las organizaciones.Es por ello que el presente artículo revisa el estado del arte de la sustentabilidad y la ética en las organizaciones, para comprender su aplicabilidad en la gestión y distinguir los actores relevantes. Para ello, utiliza una metodología de revisión bibliográfica, seleccionando y analizando cincuenta publicaciones que tratan estos temas desde diversas disciplinas.El hallazgo del análisis indica que la perspectiva de las organizaciones como sistemas socioecológicos promueve valores basados en la ética y es una alternativa de abordaje de la sustentabilidad organizacional. Desde esta mirada los actores sociales, ambientales y económicos que tienen un interés o son afectados por la acción o inacción de una empresa -los stakeholders-, cobran un especial interés y prestigio, dado que las bases de las relaciones entre lo social y lo ambiental es lo que repercute finalmente en la sustentabilidad o insustentabilidad de un sistema.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242687,"idioma_id":5,"titulo":"ESTILOS DE APRENDIZAJE PREDOMINANTES EN PROFESIONALES, Y COMPARATIVO CON ESTUDIANTES","resumen":"Se han descripto en los adultos diferentes estilos de aprendizaje (EA): activo (A), reflexivo (R), pragmático (P) y teórico (T), y cada persona tiene una preferencia particular para cada uno de los cuatro. A su vez, hay estrategias educativas que se adaptan mejor a cada uno de ellos. Objetivos. Comparar en forma individual cada uno de los estilos de aprendizaje entre alumnos de la carrera de medicina y profesionales. Comparar entre los profesionales los diferentes EA según su especialidad. Relacionar la capacitación docente previa y la actividad docente actual. Establecer una comparación entre diferentes EA según la presencia o ausencia de capacitación docente previa y de actividad docente actual. Determinar los predictores de puntajes más altos en los diferentes EA. Material y métodos. Diseño prospectivo, observacional, transversal y analítico. Se incluyó a 22 profesionales, participantes de un curso de pedagogía, y 53 alumnos de una unidad hospitalaria. Se realizó en 2010. Se aplicó un cuestionario de estilos de aprendizaje, y estadística descriptiva, inferencial y regresión lineal. Resultados. El 62,66% son mujeres. Edad: profesionales (PR): 38,72 ± 1,84, y estudiantes (ES): 27,92 ± 1,84. Entre los PR: 63,63% son egresados de la Universidad de Buenos Aires (UBA), 72,72% tienen especialidades clínicas, la antigüedad profesional es de 15,54 ± 1,84 años. Se compararon los EA en PR versus en ES: para p 9,00 ± 2,50 versus 6,00 ± 2,00, p 0,02; no significativa (pNS) para A, R y T. Especialidades clínicas versus quirúrgicas pNS para los cuatro EA. Presencia o ausencia de cursos de docencia previos pNS para los cuatro EA. Presencia o ausencia de actividad docente actual pNS para los cuatro EA. Predictores de mayores puntajes: tipo de universidad pNS para los cuatro EA; mayor edad p 0,02 para A y pNS para R, T y P; mayor antigüedad profesional p 0,03 para A y pNS para R, T y P. Conclusiones. No hay diferencias entre el aprendizaje por estilos activo, reflexivo y teórico entre profesionales y estudiantes, pero sí en cuanto al pragmático, a favor de los profesionales. La mayor edad y la mayor antigüedad profesional son predictoras de mayor desarrollo del aprendizaje activo en los profesionales.&#8195;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242689,"idioma_id":4,"titulo":"Some stylized facts of the Bitcoin market","resumen":"In recent years a new type of tradable assets appeared, generically known as cryptocurrencies. Among them, the most widespread is Bitcoin. Given its novelty, this paper investigates some statistical properties of the Bitcoin market. This study compares Bitcoin and standard currencies dynamics and focuses on the analysis of returns at different time scales. We test the presence of long memory in return time series from 2011 to 2017, using transaction data from one Bitcoin platform. We compute the Hurst exponent by means of the Detrended Fluctuation Analysis method, using a sliding window in order to measure long range dependence. We detect that Hurst exponents changes significantly during the first years of existence of Bitcoin, tending to stabilize in recent times. Additionally, multiscale analysis shows a similar behavior of the Hurst exponent, implying a self-similar process.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242690,"idioma_id":4,"titulo":"Hydrocolloids in wheat breadmaking: A concise review","resumen":"The present review analyzes the effect of the most common hydrocolloids on diverse aspects of wheat breadmaking. This encompasses exudate gums, gums from seaweeds, modified celluloses, pectins, galactomannans from leguminous seeds and exopolysaccharides from microbial fermentation. Hydrocolloids are employed to improve dough performance, bread characteristics and sensorial quality. They are also added to minimize non desired changes in crumb texture during storage (anstistaling effect). In bake off technologies (frozen dough, par-baked bread) they can help to preserve the structure from damage by freezing thus rendering acceptable products. Finally, nutritional improved mixtures of wheat and other flours can take advantage from hydrocolloids addition in order to compensate a diminished quality.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242691,"idioma_id":4,"titulo":"Techno-functional properties of wheat flour-resistant starch mixtures applied to breadmaking","resumen":"Resistant starch can be used to reduce the availability of carbohydrates in baked products. In this study, the effect of type 4 resistant wheat starch (RS4) on wheat flour dough and breads was evaluated. Wheat flour was substituted by RS4 at 10%, 20% and 30% w\/w (RS10, RS20 and RS30, respectively). Rheological and thermal behaviours of dough were evaluated. Besides, bread quality, starch digestibility and bread staling were analysed. All substituted dough exhibited viscoelastic behaviour but lower elastic and viscous moduli. Regarding to bread quality, specific volume and crumb texture were negatively affected in samples with RS4. However, all samples were technologically acceptable. During storage, crumb hardening was observed in breads without and with RS4 but amylopectin retrogradation was not particularly affected. The in vitro digestibility of bread with RS showed a lower release of reducing sugars and a lower estimated glycaemic index, suggesting a healthier profile for these breads.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242692,"idioma_id":4,"titulo":"Rheological and microstructural study of wheat doughs partially replaced with mesquite flour (Prosopis alba) and added with transglutaminase","resumen":"The incorporation of different flours into wheat bread may pursue different objectives, such as increasing the nutritional quality of the products or the recovery of flour with little use in the industry. The ?mesquite flour' (MF) is rich in sugar, fiber and protein, and is an interesting additive to wheat flour in baking. In this study, we used crude and thermally processed bread dough formulations of wheat flour (WF), replacing 15%, 25% and 35% with mesquite flour. Furthermore, each formulation was tested for two levels (0.01% and 0.1%) of the enzyme transglutaminase (TG). Dough rheology was studied by small amplitude oscillatory compression tests, and the microstructure was analyzed by laser confocal microscopy using fluorescein isothiocyanate and rhodamine B as fluorophores. It was concluded that the incorporation of mesquite into the dough resulted in changes in the structure, as evidenced by the increase in tan &#948;, microscopic observations (loss of the filamentary and cross-linked gluten structure) and by the increase in the gelatinization temperature. The addition of TG led to dissimilar effects on doughs, depending on the formulation (wheat\/mesquite content), but most encouraging results indicate the recovery of the structure, evidenced by a reduction in tan &#948; and the generation of a more filamentary structure in the dough with a higher content of mesquite flour. However, the effect of TG addition on ?processed dough? was attenuated and the viscoelastic matrix of gluten did not recover.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242693,"idioma_id":4,"titulo":"Technological quality of dough and breads from commercial algarroba-wheat flour blends","resumen":"Algarroba flour would be useful to supplement lysine-limiting systems such as wheat flour due to its aminoacidic composition. Thus, the effects of adding this flour (10%, 15%, 20% and 30%) to wheat flour in dough quality and breadmaking performance were studied. Dough rheology was tested using the farinograph, oscillatory rheometry and texture profile analysis (TPA); molecular mobility was evaluated by nuclear magnetic resonance and thermal properties were analyzed with differential scanning calorimetry and viscoamilogram. Bread quality was evaluated by: specific volume, color and texture of crumb. Samples with algarroba flour exhibited higher water absorption, development time and degree of softening and lower stability than wheat flour. Algarroba flour led to softer, less adhesiveness and elastic doughs whereas cohesiveness was improved at intermediate levels. These samples showed lower G? and G? values than control, although with the formation of more elastic structure at 30% algarroba flour. In addition, algarroba produced a protective effect on starch granule disruption with high denaturation temperatures and low values of enthalpy. Breads with increasing levels of algarroba flour presented lower specific volume values than control, reaching the highest decrease (15%) with 30% of algarroba. Breads crumbs with algarroba exhibited higher values of hardness and resilience. The use of algarroba flour led to breads with quite a lower quality than control. Despite of this, algarroba due to its taste and aroma properties and due to it being a source of fiber and proteins of high biological value would be an adequate ingredient for bakery products.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242697,"idioma_id":5,"titulo":"IMPLANTES PEEK DE ÚLTIMA GENERACIÓN. ESTUDIO AL MEB","resumen":"El PEEK, poli-éter-cetona, es un termoplastico de doble fase, biomaterial utilizado para reemplazar los implantes con componentes metálicos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242698,"idioma_id":5,"titulo":"ESTUDIO COMPARATIVO  DE LA TOPOGRAFÍA Y COMPOSICIÓN QUIMICA ENTRE IMPLANTES DEZIRCONIO Y TITANIO","resumen":"Los fenómenos de la oseointegración de los implantes dentales dependen de características fisico-quimicas de los dispositivos y de las condiciones del hospedador. El prpósito del presente trabajo fue comparar la topografía y composición química de 5 implantes de zirconio y 5 de titanio. Se analizaron distancias intercrestales y la altura de las crestas mediante Microscopía Electrónica de Barrido (MEB). La composición química se estudió con difracción de rayos X (EDAX. Fue utilizada la prueba estadística de Varianza para analizar las medidas intercrestales y las alturas de las crestas considerando como numero significativo p<0.05. Las medidas de las medias de las distancias intercrestales  en los implantes de titanio fue de  644 micrómetros(um) mientras que en los implantes de zirconio fue de 590 um, no habiendo diferencias significativas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242700,"idioma_id":5,"titulo":"Cualidades de los materiales utilizados para la elaboración de implantes dentarios","resumen":"Recorriendo brevemente la historia de los materiales utilizados para la confección de implantes dentarios, se puede mencionar a Branermak que introdujo los implantes de titanio en la década de  1960.Posteriormente otros científicos observan que que el criterio puede ser introducido en el campo médico ya que mostraba ser biocompatible con el sistema biológico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242701,"idioma_id":5,"titulo":"Estudio comparativo entre las técnicas citológica, citoinmunohistoquímica , histopatológica e inmunohistoquímica para el diagnóstico de leishmaniosis canina.","resumen":"En la Leishmaniosis Visceral, los amastigotes pueden ser identificados por tinción con Giemsa en preparaciones o secciones de tejidos obtenidos de lesiones en la piel, bazo, hígado, médula ósea y aspirados de nódulos linfáticos. Se debe considerar un resultado positivo, la aparición de una sola célula parasitada. El diagnóstico puede ser no exitoso debido a la baja sensibilidad de los métodos histológicos tradicionales para detectar el parásito. Los métodos inmunohistoquímicos para detección de Leishmania en tejidos, son simples, no necesitan un equipamiento especial y son altamente sensibles y específicos. El objetivo de este estudio fue evaluar las técnicas consideradas más sensibles y específicas para el diagnóstico de Leishmaniosis Visceral. Se obtuvieron muestras de caninos correspondientes a zonas del Nordeste Argentino. Fueron seleccionados un total de 42 pacientes caninos con diagnóstico serológico reactivo a Leishmania a los cuales se les extrajo muestras por medio de punción de médula ósea. También se obtuvieron muestras por biopsia de piel proveniente del pabellón auricular para coloración de H y E e inmunohistoquímica. En la observación microscópica de los extendidos de médula ósea de los 42 animales se observó amastigotes de Leishmania con la coloración de Giemsa. Con la técnica de inmunocitoquímica solo el 70% de las muestras reccionó a esta prueba marcando los parásitos. En los cortes histológicos se pudo identificar amastigotes de Leishmania con la técnica inmunohistoquímica en el 100 % de los casos. Mientras que, con la coloración H y E, el 65% de las muestras dieron positivas a la presencia de amastigotes. En el caso de bloques parafinados la técnica inmunohistoquímica mostro mayor sensibilidad en la detección de amastigotes de Leishmania. En cuanto a las muestras citológicas mostró mayor utilidad la coloración con Giemsa ya que permite detectar no solo la presencia de amastigotes de Leishmania sino también de otros microorganismos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242704,"idioma_id":5,"titulo":"Los impactos del turismo en Tupungato. Una mirada Sustentable","resumen":"The project arises from a viewpoint that has as its central axis the Public Interest, searchs, explores and assess the socio-cultural, economic and environmental impacts, while analyzing the role that different stakeholders have on tourism related activities in the Tupungato in Mendoza.There in the Plan Estratégico de Desarrollo Sustentable e Innovación Turística 2024 for the Valle de Uco, general guidelines and some programs, but this is not a strategic development plan formally designed and specific background for Tupungato are scarce and incomplete.Since the concept of sustainability and tourism seeks to achieve, through proper planning, that these impacts to affect the environment in a positive way.From an academic reflection, it seeks to reflect a commitment to the community contributing to Tupungato the first guidelines to work on a real stage based on responsible measurements, updated information, from the perspective of an interdisciplinary professional team that could set the starting point for the future development of a strategic plan for tourism development in the Department.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242705,"idioma_id":5,"titulo":"ALGUNAS REFLEXIONES SOBRE LA RACIONALIZACIÓN","resumen":"El conocido proceso de racionalización de denominadores (de acuerdo a cómo se presenta en los textos escolares) consiste en la transformación de una expresión con radicales en el denominador en una expresión equivalente que no los tiene. Es una técnica muy popular y extendida,no solo en la enseñanza media sino también en otras instancias educativas.Como se desprende de los libros de textos (y de nuestra propia experiencia docente) el abordaje se lleva a cabo introduciendo el concepto de conjugado: el conjugado de la expresión a + b es a-b. Esta definición es la que denominamos definición escolar de conjugado.Debemos recordar que llegados a esta instancia, ya hemos trabajado en forma profusa con todo tipo de radicales y así, un alumno podría preguntarnos cómo racionalizar una expresión con radicales de índice 3 por ejemplo.¿Cuál sería la noción adecuada de conjugado en este caso?; ¿siempre será posible racionalizar una expresión que involucre radicales de orden arbitrario?; ¿por qué incluimos la noción de conjugado en el proceso de racionalización? La definición escolar y los textos no proporcionan respuestas a esta preguntas.El objetivo de este taller es entonces dar algunas respuestas (parciales, para nada definitivas)a las preguntas mostrando que estos problemas pueden abordarse desde otras perspectivas, en concreto, desde el álgebra lineal. En el camino serán evidentes ciertos errores que se deslizan en la enseñanza de estas nociones. A partir de ejemplos sencillos, quedarán expuestas las ambigüedades de la definición escolar y los malos entendidos que acarrea. Una consecuencia es que obliga a realizar un recorte tal que es muy acotado el campo de problemas que pueden resolverse.La propuesta implícita, propone un recorte y un posible acercamiento a la resolución de estos problemas con la esperanza de que tengamos más herramientas para intervenir en nuestra clase, para plantear estrategias didácticas que permitan encarar este problema con una mayor comprensión y rigor. Al mismo tiempo, ante la persistencia de ciertos errores nos interesa poner en cuestión los modos en que estas nociones son problematizadas durante la formación deprofesores de matemática, con el interés de generar una discusión genuina al respecto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242707,"idioma_id":5,"titulo":"Nuevos registros para la familia Xylariaceae (Ascomycota) en Argentina","resumen":"Camillea scriblita y Nemania immersidiscus son registradas por primera vez para la micobiota Argentina. Se incluyen descripciones e ilustraciones de estas especies y de Phylacia turbinata, recientemente reportada para Argentina. Además se presenta un mapa con la distribución de los taxones conforme a sus registros en el Neotrópico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242710,"idioma_id":4,"titulo":"Effects of heat and cold shock-induced triploidy on productive parameters of silver catfish (Rhamdia quelen) late-hatched in the reproductive season","resumen":"This study was carried out in order to assess the productive performance of triploids of silver catfish (Rhamdia quelen) obtained by heat (HT) and cold shock (CT) at the end of the reproductive season. In hatchery, HT larvae reached the highest survival rate since they exhibited the lowest cannibalism rate among all groups. Although mean weight of larvae in HT group was lower in comparison with CT and diploid counterparts, the final biomass of HT was the highest due to the great survival rate observed in this group. At the end of the fattening trial both HT and CT groups showed better productive parameters than diploid control group. The mean weight of HT and CT were significantly higher than diploids. The condition factor was significantly higher in HT in comparison with CT and diploid fish. However, only CT males and females showed significantly higher carcass weight than control fish. Also carcass yield was greater in triploid females although only CT males displayed significantly higher carcass yield than their diploid counterparts. The gonadosomatic index (GSI) exhibited a different pattern in each sex. In males, CT showed a significantly lower GSI in comparison with HT and diploid fish. Control females displayed the highest GSI with significant differences with both triploid groups. In addition, CT males and females accumulated significantly higher percentage of abdominal fat than their control counterparts. A strong negative correlation between GSI and carcass yield in females was observed. These results demonstrate that HT and CT of R. quelen exhibited superior productive parameters than control fish in both hatchery and fattening period. Since some variables assessed were better in HT while others were improved in CT group, the election of heat or cold shock-induced triploids for culture should be based on the productive aims of each fish farm.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242711,"idioma_id":5,"titulo":"Cambiemos la progresividad de la pena. La contrarreforma conservadora","resumen":"http:\/\/revistabordes.com.ar\/cambiemos-la-progresividad-de-la-pena\/","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242716,"idioma_id":5,"titulo":"causas directas que inducen el cambio de uso del suelo y de la cobertura boscosa, a escala de paisaje, en el sur de Venezuela","resumen":"Las causas directas que inducen el cambio de coberturaboscosa por cambios en el uso del suelo han sido identificadascomo categorías generales. Sin embargo, estas categoríasno captan la forma diferenciada en que las personas respondena las oportunidades socioeconómicas que impulsan los cambiosen el uso del suelo a escala local. Se determinó si las causas, anivel individual, que inducen el cambio de la cobertura boscosaal usar la tierra son similares en los mosaicos del paisaje de lacuenca alta del río Botanamo, en el sur de Venezuela. Se identificaronlos actores con mayor potencial de impactar el bosqueen la cuenca y se caracterizaron en tres dimensiones: socioeconómica,manejo y tenencia de la tierra y cambios de uso\/cobertura,a partir de la aplicación de cuestionarios semi-estructurados. Cada encuesta fue georreferenciada para relacionarlacon los mosaicos del paisaje y se utilizó análisis discriminantepara identificar las variables que contribuyen a diferenciar entremosaicos. Los ganaderos y residentes agricultores criollosson los actores que más impactan el bosque y las causas impulsorasdirectas que inducen los cambios difieren en los tresmosaicos del paisaje: bajos ingresos familiares en el mosaicode bosque continuo y sin uso aparente, unidades de producción<10ha en áreas de expansión urbana, y grandes unidades deproducción pecuaria (500-5000ha) en el mosaico más fragmentado.Los resultados indican que las causas directas de la deforestaciónen la cuenca están acopladas con cambios espacialesy temporales del paisaje.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242717,"idioma_id":5,"titulo":"La vegetación de la Argentina","resumen":"proximamente","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242718,"idioma_id":5,"titulo":"El reconocimiento en comunicación\/educación. Esbozos para una categoría en construcción","resumen":"En este artículo se presentan nociones acerca del reconocimiento. Se toman como punto de partida los aportes a la teoría social de Axel Honneth, Nancy Fraser y Paul Ricoeur. Estas posiciones conceptuales se conjugan para reflexionar acerca de una categoría de comunicación\/educación. La problemática del reconocimiento siempre ha estado presente en este campo. Nombrada de una u otra forma, esta cuestión plantea una recurrencia posible que consiste en preguntarse por la intervención concreta en ámbitos, instituciones y organizaciones político-culturales. Para ello, se considera cómo ha sido trabajada en este campo a partir de los trabajos de Paulo Freire y de Jorge Huergo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242725,"idioma_id":5,"titulo":"Descripción del movimiento de burbujas en una copa de espumante de naranja","resumen":"El presente artículo, desarrollado en el marco del trabajo de tesis doctoral 'Desarrollo de espumante de naranja. Estudio de la formación de burbujas aplicando análisis de imágenes', muestra la aplicación de la Física al estudio de atributos de calidad de un producto alimenticio innovador, empleando técnicas de análisis de imágenes. De esta manera, se podrán caracterizar las propiedades espumantes, mediante una metodología no destructiva y sencilla de reproducir, posibilitando el re-procesamiento de las muestras de imágenes obtenidas, tantas veces como se deseen, para describir otros aspectos del producto y\/o con fines educativos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242854,"idioma_id":4,"titulo":"Laccaria fraterna (Agaricales, Basidiomycota) associated with exotic Eucalyptus sp. in Northern Argentina and Paraguay","resumen":"Laccaria fraterna is recorded for the first time from the Cordillera Department, Paraguay and from the north of Argentina. Both macroscopic and microscopic morphological characteristics of the basidiomata are described. Photographs of fresh material are presented along with photographs of the microscopic characters. Comments regarding the distribution and taxonomy are provided.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242856,"idioma_id":5,"titulo":"El ciudadano de las barracas. Genealogía del servicio militar como problema y preocupación en los cuadros militares argentinos en la esquina de los siglos XIX-XX","resumen":"El objetivo de este artículo está en precisar la genealogía de una forma de reflexión específica en el pensamiento militar, aquella que diagramó y sostuvo en los primeros años del siglo XX el espacio de un servicio militar obligatorio como forma óptima de relación del ejército con la población masculina. Al hacerloesbozó como una de sus principales razones un modelo de ciudadanía que sería profundizado en las décadas siguientes, el ciudadano de las barracas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242857,"idioma_id":5,"titulo":"Innovación y crecimiento en el sector agropecuario. Problemáticas de la innovación en la producción familiar de té en Misiones","resumen":"La Provincia de Misiones es la principal productora de té en Argentina. A nivel primario se observan diferencias de rendimientos por hectárea superiores al 250% entre productores de niveles tecnológicos bajos y altos, no explicadas por cuestiones agroecológicas. El objetivo fue indagar los factores limitantes de la adopción de tecnología (en siembra, manejo del cultivo y cosecha) de productores pequeños y medianos de te mediante un enfoque cualitativo (técnica de grupos focales). Entre las limitantes de adopción de tecnologías se detectan restricciones económicas y de conocimiento. Asimismo, se menciona asimetría comercial entre productores y las empresas procesadoras de té, ausencia del Estado y debilidad organizacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242859,"idioma_id":5,"titulo":"Racionalidad militar e ingreso voluntario al ejército a fines del siglo XIX. Ideas, sueños e hipótesis de una batalla perdida","resumen":"El artículo se dedica a reponer una forma de reflexión militar que a lo largo de las últimas dos décadas del siglo XIX propuso un vínculo flexible entre el ejército y la población masculina, rechazando el proyecto de un servicio obligatorio. Se restituyen las principales líneas argumentales y se identifican las coyunturas críticas que provocaron un desplazamiento en las inquietudes, la formulación de otros diagnósticos y la emergencia de nuevas preocupaciones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242860,"idioma_id":5,"titulo":"'Alejandro Rubio: régimen político de un imaginario mediático'","resumen":"En el siguiente trabajo abordamos ?en clave política? las operaciones estéticas de la literatura de Alejandro Rubio, donde el discurso massmediático, el literario y el de la política en sentido estricto aparecen como maneras de producir ficciones que se entrecruzan. Desde el plano estético, Rubio sustituye un orden por otro, plantea ?actos estéticos que dan lugar a nuevos modos de sentir e introducen nuevas formas de subjetividad? (Rancière). La transgresión mediática, las técnicas del montaje y el pastiche, la subversión de la jerarquía entre lo alto y lo bajo y el trabajo con un lenguaje mediatizado son actos estéticos al interior de un sistema que trastoca los regímenes de visibilidad, esto es, ?los lugares y la cuenta de los cuerpos? (Rancière), y forman parte de maneras marginales de producción que se vuelven explíctamente políticas en tanto están al servicio de que lo privatizado se vuelva público. A partir de aquí, intentamos pensar cómo repone un régimen de apariencia usando como principal materia prima elementos cristalizados mediáticamente por una política de la simulación, es decir, una política que se ocupa de que todo esté en su lugar asignado.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242862,"idioma_id":5,"titulo":"?Cuestión de peso: Pablo Katchadjian y su ?Aleph engordado??","resumen":"Abordamos El Aleph engordado (2012) de Pablo Katchadjian a partir de una hipótesis orientada a demostrar que no solo el texto sino el artefacto metódico que construye Katchadjian produce más una tensión que una continuación del original. En una segunda instancia nos detenemos en la polémica que despierta su publicación a partir de la demanda por defraudación de los derechos de autor que le inicia María Kodam, para analizar las morales literarias que se ponen en conflicto: por un lado, la que se corresponde con el nuevo ambiente mediático y postula una 'cultura libre', y por el otro una que pervive paralelamente enfatizando el principio legal de la autoría y los alcances del 'copy right'.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242863,"idioma_id":5,"titulo":"'Entre la inmaterialidad y el énfasis físico: algunos experimentos literarios en el contexto digital'","resumen":"Teniendo en cuenta las experiencias de ?desmaterialización del objeto? que experimentaron las neovanguardias de la década del sesenta nos proponemos abordar un corpus de literatura digital argentina desde el punto de vista de su materialidad. Específicamente, nos referimos a Manifiestos Robots (2009) de Belén Gache, los ensayos textuales (2010) (2014) (2017) de Milton Läufer y El peronismo spam (s\/n) de Charly Gradin. Siguiendo los conceptos de ?materialidad formal? y ?materialidad forense? cristalizados por Matthew Kirshenbaum (2008), a partir de dicho corpus recuperamos la inquietud sobre la materialidad de obras aparentemente desmaterializadas. Para ello efectuamos un análisis de procedimientos plásticos que llevan a un nivel material el signo lingüístico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242865,"idioma_id":4,"titulo":"Economic performance assessment and monitoring in LP-DMC type controller applications","resumen":"One of the main reported problems in petrochemical applications of Linear Programming-Dynamic Matrix Control (LP-DMC) type controllers is their global performance assessment. Since the stationary optimization and dynamic control blocks have not a transparent link between them, it is not easy to find appropriate references to evaluate the overall performance, and more important, to clearly determine the causes of an eventual loss of performance. In this work, the whole LP-DMC problem is analyzed and an off-line underlying optimization problem is defined, whose solution is used as a benchmark for the global closed-loop behaviors study. Based on this idea three global indicators, which evaluate and diagnose poor controller performance, are proposed. The indicators were successfully tested in two case studies: an integrating system and the well-known Shell heavy oil fractionator.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242868,"idioma_id":4,"titulo":"Modelización de relaciones entre magnitudes geométricas en un entorno enriquecido con TICs: actividades para la escuela secundaria, diseñadas en un grupo colaborativo","resumen":"Presentamos aquí avances de nuestra investigación que aborda el problema didáctico de integrar las TICs en las clases de matemática de nivel secundario. En este artículo nos referiremos a la instancia del diseño de actividades para el aula en torno a la modelización de relaciones entre magnitudes geométricas. Disponer de una modelización intramatemática en un entorno de geometría dinámica para el estudio de la variación de magnitudes asociadas a la situación, nos permiten plantear, entre otras cuestiones: condiciones que contribuyen en el aula a la distinción entre una situación geométrica y su modelo dinámico; la incidencia de algunas características del funcionamiento del programa en el trabajo matemático de los estudiantes y, finalmente, la configuración del área de trabajo de un entorno de geometría dinámica como variable didáctica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242869,"idioma_id":5,"titulo":"Compras y corrupción en el sector privado. Aplicación de las herramientas de la calidad a la gestión de adquisiciones de una organización educativa y propuestas de mejora","resumen":"This article deals with the issue of corruption in the private sector, focusing especially on the process carried out by different types of organizations for the purchase of material resources (goods, products, etc.). It is based on the hypothesis which states that the absence of internal regulations and procedures for members of an organization to follow means a potential risk of disloyal or corrupt practices. For this reason, the importance of dictating rules, unifying and organizing the behavior of an organization is highlighted. Taking the University of Durango Campus Morelia (UDCM) as a case study, a general purchase procedure for the University is proposed. This procedure is based on the knowledge and analysis of the information provided by the directors and employees of the institution already mentioned, from direct observation, from the review of relevant documentation and the implementation of the corresponding quality tools: affinity diagram, relations diagram and tree diagram. Apart from complementing the organization?s scenario, these tools allow for identifying the different strategies to achieve the aim of improving purchase management and of reducing corruption risks.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242870,"idioma_id":4,"titulo":"Evidence of size dependent effect of silica micro and nanoparticles on basal and specialized monocytes functions","resumen":"Aim: To analyze the effect of silica particles on monocyte\/macrophage functions. Materials & methods: Silica micro- and nanoparticles were obtained by the Stöber method. Their effect on monocyte\/macrophage proliferation, activation, membrane integrity and metabolic activity were determined. Results: Silica particles inhibit cell proliferation while 10 nm nanoparticles (NPs) did not affect it. Similarly, silica particles induced strong cell activation. However, 10 nm NPs do not alter IL-12 or nitrite levels. Furthermore, bigger NPs and microparticles increase cell membrane damage and reduce the number of living cells but smallest NPs (10 and 240 nm) did not. Conclusion: Cell activation properties of silica particles could be useful tools for immune stimulation therapy, while 10 nm NPs would be suitable for molecule transportation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242871,"idioma_id":4,"titulo":"Comparison of two sedation protocols for short electroretinography in cats","resumen":"AbstractObjectives The objectives were to compare two different sedative combinations, xylazine?ketamine anddexmedetomidine?ketamine, on the short electroretinography (ERG) protocol and their impact on sedative effect,reversal times and physiological variables in cats.Methods Six healthy spayed female domestic cats were sedated using one of two ketamine-containing protocols:intramuscular xylazine hydrochloride (1 mg\/kg) plus ketamine hydrochloride (3 mg\/kg) (XK), and dexmedetomidinehydrochloride (5 &#956;g\/kg) plus ketamine hydrochloride (3 mg\/kg) (DK). A short ERG protocol was recorded fromthe left eye of each cat under XK and DK sedation. Thirty minutes later, the effects were reversed with yohimbineor atipamezole for the XK and DK treatment, respectively. The cats were evaluated for time to recumbency, timeto head elevation, and time to standing position after reversal treatments. Other variables recorded were: systolicblood pressure, cardiac rhythm, heart rate, pulse oximetry and respiratory rate. Recorded ERG variables includeda- and b-wave amplitudes and implicit times under photopic, scotopic and scotopic mixed ERG conditions.Results Time to lateral recumbency with XK was shorter than for DK (P 0.05).Conclusions and relevance The present study shows that XK and DK treatments are chemical restraint alternativesfor ERG recording in cats, with only significant differences in the photopic b-wave amplitude.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242872,"idioma_id":5,"titulo":"América del Sur y Central en el comercio internacional","resumen":"América del Sur y Central se han caracterizado por una inserción históricamenteperiférica en el comercio mundial, con una fuerte dependencia en la exportación deproductos primarios, combustibles y minerales, conjuntamente con manufacturas debajo valor agregado.La división internacional del trabajo asignó a estas regiones del continentedichas funciones exportadoras, exponiendo a los países a la alta volatilidad de los precios internacionales, lo que genera un impacto en sus balanzas comerciales y un ingreso fiscal por parte del Estado. El trabajo retoma esta línea de estudio y presenta los datos que permiten comprender esta dinámica en el comercio.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242873,"idioma_id":5,"titulo":"La importancia de la Investigación en el Comercio Internacional","resumen":"El Tercer milenio se puso en marcha y la sociedad del conocimiento demanda fuertes exigencias en el campo de la investigación social.  En este contexto estudiantes, docentes y actores del comercio internacional y los negocios, no están exentos de este escenario dado lo dinámico de su experticia y las actividades que desarrollan.La comprensión de las tendencias globales se enmarca en la necesidad de revisar permanentemente el conocimiento disponible y ampliarlo, y es aquí donde entra en juego la importancia de la investigación con fines formativos.Trabajos de grado y posgrado, formulación de proyectos que propongan acciones tendientes a la mejora de problemáticas relevantes, abordaje de nuevas líneas teóricas que articulen un acceso con las prácticas del área experta como es el Comercio Internacional, son algunos de los tópicos que nos convocan.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242874,"idioma_id":5,"titulo":"El Fondo Monetario Internacional","resumen":"Este artículo tiene como propósito describir brevemente las propuestas para lacreación de este organismo en contexto de su creación, para que se lo creó y cuáles son los objetivos que persigue en materia de cooperación internacional.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242875,"idioma_id":5,"titulo":"Las exportaciones de mercancías de América Latina y el Caribe: tendencias vs. coyuntura","resumen":"El propósito de este trabajo es hacer una observación sobre la variación en latasa que muestra el valor de las exportaciones de mercancías en América Latina y el Caribe en el comercio mundial desde 2014 hasta el primer semestre del 2017.Según informes de diferentes organismos de cooperación internacional, principalmente la Comisión Económica para América Latina y el Caribe -CEPAL- y el Banco Interamericano de Desarrollo -BID-, concuerdan en que las exportaciones de mercancías de esta región han padecido una baja alcanzando su mínimo durante el año 2015. Prácticamente esta contracción en las exportaciones de la región fue un proceso de cuatro años consecutivos que parece haber comenzado a revertirse en el 2016 y el 2017.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242876,"idioma_id":5,"titulo":"El proceso de investigación y la lógica circular de la enseñanza y el aprendizaje","resumen":"Todo campo del conocimiento cualquiera denominemos, se encuentra en permanente diálogo entre el mundo de las ideas y la realidad empírica.  A partir de ello es que se hace necesario detenernos en las prácticas profesionales, problematizarlas y realizar un encuadre teórico que, en un proceso circular, les otorgue sentido.Así, la acción científica se fundamenta en una triple alianza entre la práctica social, la teoría y el método, elementos que se encuentran fuertemente interrelacionados. Cea D´Ancona (1999) pone de manifiesto que la práctica social se define como una forma de actividad mediante la cual el sujeto modifica una realidad exterior a él y lo conduce a cambios en sus relaciones económicas, sociales y culturales.  La teoría que, sin representar una verdad absoluta (ya que se define temporalmente) proporciona una explicación aproximada de un sector de la realidad y, por último, el método que garantiza el adecuado tratamiento del problema conduciendo al éxito de la investigación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242878,"idioma_id":5,"titulo":"Calidad de aguas y análisis de la contaminación en el río Tunuyán Superior (Mendoza ? Argentina) en el periodo 2007-2014","resumen":"Desde agosto de 2007 a la fecha, se ha venido conformando una base de datos de calidad físico-química-microbiológica del agua de riego del río Tunuyán superior, uno de los más importantes de Mendoza. Se seleccionaron seis sitios de muestreo, de lectura mensual, estratégicamente ubicados. Tres sitios pertenecientes al río: Valle de Uco (VU), Costa Anzorena (CA) y Dique Tiburcio Benegas (TB) y otros tres a sus afluentes principales: río Las Tunas (LT) y arroyos Aguanda (A) y Yaucha (Y). Son objetivos del trabajo: (1) poner a disposición de los interesados la base de datos de registros mensuales de parámetros medidos; (2) caracterizar al agua de la cuenca; (3) identificar las fuentes de contaminación de mayor impacto; (4) comparar la evolución temporal y espacial de la contaminación y (5) aportar a la elaboración de pautas de gestión transferibles a la administración del recurso hídrico. El trabajo presenta la variación espacial y temporal de los diferentes parámetros analizados los que fueron sometidos a un análisis estadístico no paramétrico (Kruskal Wallis). Se observa que la salinidad del agua expresada como conductividad eléctrica arrojó valores bajos en los sitios: LT, A y Y y bastante más altos en: VU, CA y TB, pudiendo comprobarse además una tendencia creciente en dichos sitios. Los valores de salinidad más elevados se encuentran en TB (1.414 µS.cm-1), seguidos por CA (1.368 µS.cm-1) y VU (1.238 µS.cm-1). En estos tres sitios, los valores de la Relación Adsorción de Sodio (RAS) fueron también los más altos.  Con respecto al contenido de Coliformes fecales los sitios CA y TB superaron los valores máximos establecidos por la Resolución 778\/96 del Departamento General de Irrigación. Respecto a la evolución temporal los únicos parámetros que han presentado diferencias significativas (&#945;<0,05) son la Demanda Química de Oxigeno, el Oxígeno Disuelto y Coliformes fecales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242881,"idioma_id":4,"titulo":"Syndesmorion stellatum (Fija&#322;kowska) Foster et Afonin chlorophycean algae and associated microphytoplankton from lacustrine successions of the La Veteada Formation (late Permian), Paganzo Basin, Argentina. Paleoenvironmental interpretations and stratigrap","resumen":"A diverse microphytoplankton assemblage recovered from terrestrial deposits of the La Veteada Formation, north of the La Rioja Province, Paganzo Basin, Argentina, is described and illustrated. The ~ 180 m thick sedimentary type section of the unit in the Los Colorados anticline is composed of a basal gray silcrete covered by gypsum beds and a thick succession of purple mudstones inter-layered with varicolored fine sandstone sheets and laminated yellowish dolomites. The aquatic assemblage is mainly characterized by a great variety of Syndesmorion stellatum (Fija&#322;kowska) Foster et Afonin coenobia, recorded for the first time in the late Permian Gondwanic realm. All the previous morphotypes described for this chlorophycean alga are recognized in this assemblage, and new polymorph-coenobia are described and illustrated. The diversity of coenobia morphotypes of this alga is likely to reflect response to stress conditions. The genera Maculatasporites and Mehlisphaeridium are commonly present, and their algal origin is discussed. Maculatasporites gondwanensis, Maculatasporites amplus, Mehlisphaeridium parvum, and Mehlisphaeridium regulare and Mehlisphaeridium sp. are also described and illustrated. Representatives of the zygnematacean algae, Brazilea scissa, Brazilea plurigenus, Brazilea sp. A, Tetraporina tetragona, ?Lecaniella sp., as well as large clusters of sphaeromorphs incertae sedis chlorophyta algae, are described. In addition, planar colonial chlorococcalean Pediastrum-like forms suggesting hydrodictyaceaen algae are recorded for the first time in late Paleozoic strata of Argentina, and the zygnematalean affinity of Reduviasporonites chalastus as green algae is discussed. The highly diverse La Veteada microphytoplanktonic assemblage is composed by algae that grew in hypersaline lacustrine environment associated with usually fresh-water\/brackish taxa or even those tolerant to certain salinity taxa washed after heavy rainfall and\/or floodings into depositional site. In general terms, the land-derived palynological composition of the La Veteada assemblage at Central Famatina Range reflects parent vegetation adapted to arid or semi-arid climate as reported from late Guadalupian to late Lopingian in the Paganzo Basin. The whole palynological composition suggests a Lopingian age for the La Veteada Formation at its stratotype, based on the stratigraphic range of all the land-derived miospore species recognized, resulting younger than assemblages assigned to the Lueckisporites?Weylandites Biozone (LW: Wordian?Capitanian). Therefore, it is the youngest Permian palynofloral assemblage recorded up to now in Argentina and South America.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242882,"idioma_id":4,"titulo":"PALYNOLOGY OF THE LA VETEADA FORMATION IN ITS TYPE LOCALITY (LOPINGIAN), FAMATINA RANGE, LA RIOJA PROVINCE, ARGENTINA. SPORES","resumen":"This is a systematic study of the palynological assemblages recorded in the upper part of the La Veteada Formation (La Veteada Assemblage), which constitutes the section of the type locality, La Rioja Province, Argentina. In this contribution, 38 species of trilete and monolete spores are described and\/or illustrated. Two new species are described: Lundbladispora verrucosa sp. nov., and Secarisporites triangularis sp. nov., and also a new combination of Secarisporites imperialis (Jansonius) nov. comb. is proposed. The trilete spores are one of the dominant groups of the analized microflora reducing its frequency from the base to top of the section (from 32.2% to 14.5%). Dominate the cingulate-cavate spores (derived from herbaceous lycophytes) represented by species of the genera Densoisporites-Densosporites-Lundbladispora, and Secarisporites. Smooth and apiculate trilete spores (derived from ferns and sphenopsids) are represented by the genera Calamospora, Punctatisporites, Granulatisporites, Brevitriletes, Cyclogranisporites, Osmundacidites, Verrucosisporites, Raistrickia, Foveosporites, between others. The upper section of the Veteada Formation at its type locality was deposited in fluvial-lacustrine environments under arid to semiarid climatic conditions. Semiperennial hypersaline\/brackish lakes dominate the sedimentation with periodic expansion and retraction episodes suggesting a low-relief setting. In the surrounding areas of these water-bodies dominated by evaporites grew the herbaceous vegetation mainly composed of the herbaceous lycopsids Isoetales, Selaginellales, Lycopodiales, and ferns. While in the flood-plain, herbaceous vegetation of pteridophytes (Filicales, Zygopteridales), bryophytes and herbaceous sphenophytes were developed along the river courses and in the surrounding areas of the freshwater bodies (ponds and small lakes). The presence of Densoisporites complicatus, D. nejburgii, D. playfordii, D. solidus, Leptolepidites jonkerii, Lundbladispora brevicula, L. obsoleta, L. springsurensis, L. wilmotii, Ringosporites fossulatus, Secarisporites bullatus, S. imperialis, and S. lacunatus allow confirming a Lopingian age for the upper section of the La Veteada Formation. Microfloras containing high proportions of lycopsid-tetrads are commonly recorded mainly in extra-gondwanic realm constrained to late Permian to early Triassic age.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242883,"idioma_id":4,"titulo":"INCREASING THE FISH DIVERSITY OF THE TRIASSIC FAUNAS OF GONDWANA: A NEW REDFIELDIIFORM (ACTINOPTERYGII) FROM THE MIDDLE TRIASSIC OF ARGENTINA AND ITS PALAEOBIOGEOGRAPHICAL IMPLICATIONS","resumen":"A new actinopterygian, Calaichthys tehul gen. et sp. nov. is described on the basis of a few, well-preserved specimens from the Anisian Cerro de Las Cabras Formation, Cuyo Basin in Mendoza Province. The new genus shows a combination of primitive characters (e.g. deep posterior region of the maxilla contacting the preopercle, a suspensorium backwardly oriented) and more advanced characters (e.g. distally segmented fin rays, hemiheterocercal caudal fin) and is thus considered to be a ?subholostean? fish. The new taxon is assigned to Redfieldiiformes on the basis of its single branchiostegal plate-like ray, a median gular plate, pectoral fins with stout, stiff, mainly non-segmented and distally branched fin rays, long and robust fringing fulcra in all fins, basal fulcra bordering both lobes of the caudal fin, and opposite dorsal and anal fins. Calaichthys is characterized by a combination of characters some of which are unique among redfieldiiforms (i.e. strongly ornamented but thin scales with a serrated posterior margin, smooth skull roof bones, extrascapulars with a bifid posterior margin, three suborbital bones, a hatchet-shaped preopercle, rectangular and slender opercle, deep mouth gape, entopterygoid and ectopterygoid with small pointed teeth disposed in several series, unornamented rostral bone, massive pectoral fins and delicate dorsal, pelvic and anal fins). Calaichthys provides novel information about the anatomy of redfieldiiforms, in particular in relation with the fins and associated scaly elements, as well as the scale morphology and their disposition over the body. Our work confirms for the first time that redfieldiiforms occur in South America. Redfieldiiforms seem to have originated in Gondwana and shown two diversity peaks: in the Anisian and the Carnian. Calaichthys is coeval with those redfieldiiforms of the Middle Triassic (Anisian) of Africa and Australia dwelling in ephemeral lakes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242884,"idioma_id":4,"titulo":"Fungal Biodiversity Profiles 21-30","resumen":"The authors describe ten new taxa for science using mostly both morphological and molecular data. In Basidiomycota, descriptions are provided for Botryobasidium fusisporum sp. Nov., B.Triangulosporum sp. Nov., Cantharellus hydnoides sp. Nov. and Hydnum aerostatisporum sp. Nov. in Cantharellales; Lactarius rahjamalensis sp. Nov. and Russula pseudoaurantiophylla sp. Nov. in Russulales and for Mycena paraguayensis comb. nov. in Agaricales. In Ascomycota and hyphomycetes, descriptions are provided for Colletotrichum eryngiicola sp. Nov. (Glomerellales), Corynesporella indica sp. Nov. (incertae sedis) and Repetophragma zygopetali sp. Nov. (Microthyriales).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242885,"idioma_id":4,"titulo":"Lichenomphalia altoandina , a new species of Hygrophoraceae from the Chilean Altiplano","resumen":"Lichenomphalia is a lichenized agaric genus characterized by its omphalinoid basidiomes.Lichenomphalia species are associated with unicellular green algae in the genus Coccomyxa andare mainly distributed in polar and alpine habitats. The aim of this work is to describe L.altoandina, a new species from northern Chile that grows among cushion plants over 3000 mabove sea level in the Andes Mountains. The species is remarkable for living in highly salineenvironments, in some cases virtually on salt crusts. Lichenomphalia altoandina differs from otherknown species and particularly from L. aurantiaca, the most morphologically similar species, in itssmooth and broader stipe and its slightly larger spores. Lichenomphalia altoandina is alsomorphologicaly and ecologically more similar to the core Lichenomphalia clade. Our phylogeneticstudy based on nuclear rDNA ITS and partial 28S sequences shows that L. altoandina belongs tothe Protolichenomphalia clade and is sister to an unknown lineage, L. aff. umbellifera, from NewZealand.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242886,"idioma_id":4,"titulo":"New Species of the Heterodermia comosa-Group (Physciaceae, Lichenized Ascomycota) from Southern South America","resumen":"A revision of the specimens from southern South America deposited at CTES herbarium identified as Heterodermia comosa (Eschw.) Follmann & Redón was made. As a result, four new species, viz. H. mobergiana Michlig, M.P. Rodríguez & Aptroot, H. neocomosa M.P. Rodríguez L.I. Ferraro & Aptroot, H. ramosociliata M.P. Rodríguez, Michlig & Aptroot, and H. sorediosa Michlig, L.I. Ferraro & Aptroot, all closely related to H. comosa, are here proposed. Each species is described, illustrated and commented. A distribution map is also presented.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242887,"idioma_id":4,"titulo":"First record of Macrocybe titans (Tricholomataceae ? Basidiomycota) in Argentina","resumen":"Macrocybe titans is characterized by its remarkable size, the squamose stipe surface, and the pseudocystidia with refractive content. In this paper, we describe and analyze the macro and microscopic features of Argentinian collections of this species, and provide photographs of its basidiomata and drawings of the most relevant microscopic structures. In addition, we present a map with the American distribution of M. titans, highlighting the first record of this species for the country.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242888,"idioma_id":5,"titulo":"Volvariella (Pluteacae, Basidiomycota) en el Norte de la Argentina","resumen":"Se describen e ilustran tres especies de Volvariella para el Norte de la Argentina: V. taylorii, conocida para las selvas de Yungas y Paranaense; V. subxerophytica, conocida exclusivamente para los bosques xerófilos de la región chaqueña y V. pusilla encontrada en las provincias del Chaco y Tucumán. Las dos primeras se caracterizan por poseer volva castaña grisácea y superficie del píleo fibrillosa mientras que la última se caracteriza por su volva blanca grisácea y superficie del píleo glabra a muy delicadamente fibrillosa. Se registra por primera vez para Argentina a V. taylorii y se amplía el área de distribución de V. subxerophytica para el sector oriental de la región chaqueña. Es importante destacar que V. subxerophytica era conocida sólo por el material tipo y mediante los nuevos ejemplares hallados fue posible mejorar la descripción original.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242889,"idioma_id":5,"titulo":"El fundamento constitucional de la responsabilidad del Estado. Reparación plena y reparación oportuna. Reflexiones sobre el fallo ?Ontiveros?","resumen":"El fallo de la Corte reafirma de modo explícito el carácter constitucional del principio de reparación plena. Se inscribe así en una línea jurisprudencial iniciada de modo expreso, entre otros casos, en ?Santa Coloma? y ?Gunther?. Y a pesar de que el rango constitucional de la reparación plena ya ha sido reiteradamente utilizado por la Corte Federal, su ratificación, en este momento, es especialmente valiosa como una guía interpretativa de la ley 26.944 y,sobre todo, para el caso de los estados provinciales que no han regulado la materia","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242890,"idioma_id":4,"titulo":"Nasal airflow simulations suggest convergent adaptation in Neanderthals and modern humans","resumen":"Due to its role in humidifying and warming the air before it reaches the lungs, adaptations in the internal nasal anatomy are suspected to have been essential for modern humans and Neanderthals during the settlement of Eurasian harsh landscapes. Unfortunately, the lack of soft-tissue evidence in the fossil record precludes any study of Neanderthal respiratory performance. Here, we use warping techniques to reconstruct a generic Neanderthal nose, computational fluid dynamics simulations tocompare the respiratory performance on both species, and evolutionary analyses to detect signals of selection. We report striking differences on fluid residence times under cold\/dry climatic conditions. Different from previously suggested, our results indicate that both species would have achieved an advantageous species-specific respiratory performance in cold climates.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242891,"idioma_id":4,"titulo":"Tissue tropism of Saint Louis encephalitis virus: Histopathology triggered by epidemic and non-epidemic strains isolated in Argentina","resumen":"Saint Louis encephalitis virus (SLEV) reemerged in South America, and caused encephalitis outbreaks at the beginning of the 21st century. To enhance our knowledge about SLEV virulence, we performed comparative pathogenesis studies in Swiss albino mice inoculated with two different variants, the epidemic strain CbaAr-4005 and the non-epidemic strain CorAn-9275. Only the infection of mice with SLEV strain CbaAr-4005 resulted in high viremia, invasion of peripheral tissues including the lungs, kidney, and spleen, and viral neuroinvasion. This was associated with inflammatory pathology in the lungs, spleen, and brain as well as morbidity and mortality. In contrast, neither signs of desease nor viral replication were observed in mice infected with strain CorAn-9275. Interestingly, important loss of B cells and development of altered germinal centers (GC) were detected in the spleen of mice infected with strain CbaAr-4005, whereas mice infected with SLEV CorAn-9275 developed prominent GC with conserved follicular architecture, and neutralizing antibodies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242892,"idioma_id":4,"titulo":"Pixuna virus modifies host cell cytoskeleton to secure infection","resumen":"Pixuna virus (PIXV) is an enzootic member of the Venezuelan Equine Encephalitis Virus complex and belongs to the New World cluster of alphaviruses. Herein we explore the role of the cellular cytoskeleton during PIXV replication. We first identified that PIXV undergoes an eclipse phase consisting of 4 h followed by 20 h of an exponential phase in Vero cells. The infected cells showed morphological changes due to structural modifications in actin microfilaments (MFs) and microtubules (MTs). Cytoskeletonbinding agents, that alter the architecture and dynamics of MFs and MTs, were used to study the role of cytoskeleton on PIXV replication. The virus production was significantly affected (p < 0.05) after treatment with paclitaxel or nocodazole due to changes in the MTs network. Interestingly, disassembly of MFs with cytochalasin D, at early stage of PIXV replication cycle, significantly increased the virus yields in the extracellular medium (p < 0.005). Furthermore, the stabilization of actin network with jasplakinolide had no effect on virus yields. Our results demonstrate that PIXV relies not only on intact MTs for the efficient production of virus, but also on a dynamic actin network during the early steps of viral replication.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242893,"idioma_id":4,"titulo":"Effect of K and Mn Phosphites in the control of Pythium damping-off in soybean: a feasible alternative to fungicide seed treatments","resumen":"AbstractBACKGROUNDUse of fungicide seed treatments for control of soybean soilborne diseases such as Pythium damping off has increased worldwide. However, emergence of resistant Pythium strains to metalaxyl-M has prompted need for alternative technologies to fungicides for damping-off control. Phosphites (Phis) have been proposed as methods to control oomycetes, but their use as seed treatments in soybean is limited due to lack of information on their efficacy. The effect of K and Mn phosphites (as seed treatments) in the control of Pythium damping-off in soybean was evaluated in vitro and in vivo. In vitro, treated seeds and a control were placed on potato dextrose agar and the damping-off severity caused by P. aphanidermatum (Edson) Fitzpatrick, P. irregulare Buisman, and P. ultimum Trow was assessed five days after incubation using an ordinal scale. In vivo, treated seeds and a control were planted in polyestirene pots and emergence was evaluated 21 days after planting.RESULTSAnalysis of the in vitro data using a multinomial generalized linear model showed that the probabilities for nongerminated, dead seed ranged from 0.64 to 1.00 in the control and 0 to 0.13 in the Phis in each of the Pythium species. Probabilities of germinated seed without or with damping-off symptoms were significantly higher for the Phis products than for the control. In the in vivo experiment, the Phis-based products increased seedling emergence by up to 29% on average compared to the untreated control.CONCLUSIONSMn and K phosphites are a feasible alternative to control Pythium damping-off in soybean as seed treatments. This study is the first, worldwide, to document the efficacy of K and Mn Phis in the control of soybean Pythium damping off.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242894,"idioma_id":5,"titulo":"La problemática de la resistencia de hongos a fungicidas. Causas y efectos en cultivos extensivos. Una Revisión","resumen":"La resistencia a fungicidas tiene un costo financiero para productores agropecuarios, para los fabricantesde fungicidas y para la sociedad toda. Asimismo, el surgimiento de la resistencia reduce la disponibilidadde ingredientes activos con diferente modo de acción disponibles en la lucha contra los hongos fitopatógenos, dificultando sobremanera el manejo agronómico de las enfermedades. La resistencia depende del impacto de las propiedades de cada principio activo fungicida y de la estructura genéticade las poblaciones de patógenos, como así también de las prácticas de manejo agronómico seleccionadas para cada patosistema. En consecuencia, para combatir la resistencia, el uso de los fungicidas debe enmarcarse dentro de un programa de manejo integrado de enfermedades en combinación con las buenas prácticas agrícolas que garantizan las estrategias de manejo de resistencia a fungicidas. Esta es la única manera de poder maximizar la vida útil y la eficacia de los principios activos fungicidas actualmente disponibles en el mercado, durante el mayor período de tiempo, garantizando la sustentabilidad económica y ambiental.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242895,"idioma_id":4,"titulo":"Arbuscular mycorrhiza reduces the negative effects of M. phaseolina on soybean plants in arsenic-contaminated soils   Ref: APSOIL_2017_540_R1","resumen":"All crops are negatively affected by several abiotic and biotic stresses, alone or jointly; however, some microorganisms, such as arbuscular mycorrhizal fungi (AMF), are able to alleviate them. Here, we investigated theeffects of the AMF Rhizophagus intraradices on soybean plants (Glycine max L.) grown in arsenic-contaminated soils and infected by the fungus Macrophomina phaseolina (charcoal rot). A pot experiment was carried out in aglasshouse, and three levels of As (0, 25, and 50 mg As kg&#8722;1) were evaluated. Plant and mycorrhizal parameters,disease severity, glomalin content, and arsenic content in roots and leaves were analyzed. Both arsenic and the pathogen negatively affected soybean biomass and morphological parameters. Moreover, both stresses adversely affected mycorrhizal symbiosis. Low levels of AMF colonization and vitality were observed in high As concentration and in pathogen presence; however AMF inoculation not only reduced the disease but also lowered arsenic accumulation rate in soybean biomass. On the other hands, disease severity was reduced by arsenic. Total glomalincontent, produced by the AMF was increased in arsenic-enriched substrates, but was not modified in the presence of the pathogen. Increases in glomalin production could be one of the reasons by which soybean plants accumulate lowarsenic amounts while the competition between AMF and the pathogen plays an important role in reducing the disease severity","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242896,"idioma_id":5,"titulo":"Efectos de las campañas y de las advertencias sanitarias de cigarrillo en la línea de atención al fumador en Argentina","resumen":"Las líneas telefónicas de ayuda al fumador son un medio eficaz para promover la cesación. La incorporación de imágenes y frases como advertencias sanitarias junto al número de la línea en el paquete de cigarrillos se asoció a un incremento sustancial de llamadas, comparable al logrado por fuertes campañas en mediosmasivos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242898,"idioma_id":5,"titulo":"¿Aguante la ficción?","resumen":"El levantamiento de una de las tiras más esperadas de Telefé con menos de un mes en el aire, afirma la discusión sobre la producción audiovisual de ficción en Argentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242899,"idioma_id":5,"titulo":"Una foto borrosa de la TDA","resumen":"El presente y futuro incierto de una tecnología que nació bajo los postulados de promover una televisión abierta, gratuita y plural","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242900,"idioma_id":5,"titulo":"El cine nacional en peligro  Número 15, numeros editados","resumen":"La industria audiovisual nacional atraviesa una crisis histórica que se vio movilizada por la amenaza de extinción de una de las pocas políticas públicas destinadas al sector: el impuesto a los servicios de comunicación audiovisual y a las entradas de cines.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242901,"idioma_id":5,"titulo":"La ¿revolución? del video online","resumen":"Cada vez más, el consumo se vuelve campo de complejas luchas, resultante de la tensión entre viejas y nuevas tecnologías, prácticas asumidas y renovadas, actores históricos y emergentes. Estas tensiones existieron siempre, pero tal vez en este momento histórico se hagan más evidentes debido a la feroz velocidad del impacto tecnológico. Seguramente, como en ningún otro momento en la historia, hoy en día la tecnología avanza mucho más rápido de lo que podemos ver, y, muchas veces, analizar.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242905,"idioma_id":4,"titulo":"qnrE1 , a Member of a New Family of Plasmid-Located Quinolone Resistance Genes, Originated from the Chromosome of Enterobacter Species","resumen":"qnrE1, found in a clinical Klebsiella pneumoniae isolate, was undetectable by PCR assays used for the six qnr families. qnrE1 was located on a conjugative plasmid (ca. 185 kb) and differed from qnrB alleles by 25%. Phylogenetic reconstructions of qnr genes and proteins and analysis of the qnrE1 surroundings showed that this gene belongs to a new qnr family and was likely mobilized by ISEcp1 from the chromosome of Enterobacter spp. to plasmids of K. pneumoniae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242906,"idioma_id":4,"titulo":"Molecular characteristics of mcr-1-carrying plasmids and new mcr-1 variant recovered from polyclonal clinical Escherichia coli from Argentina and Canada","resumen":"We have characterized nine mcr-1-harboring plasmids from clinical Escherichia coli isolates previously described in Argentina and Canada. Three of these plasmids carried a mcr-1-variant called here mcr-1.5. All these E. coli isolates were not clonally related and were recovered in different years and locations. However, their mcr-1-harboring plasmids showed high identity among them and to others characterized in other countries, which strongly suggests that this plasmid-type is playing an important role in spreading this mechanism of resistance to polymyxins.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242907,"idioma_id":4,"titulo":"Design, synthesis and biological evaluation of 1,3-dihydroxyxanthone derivatives: Effective agents against acetylcholinesterase","resumen":"The present work concerns the rational design and development of new inhibitors of acetylcholinesterase (AChE) based on the privileged xanthone scaffold. In order to understand and rationalize the mode of action of these target structures a theoretical study was initially conducted. From the results of rational design, a new variety of amphiphilic xanthone derivatives were synthesized, structurally characterized and evaluated as potential anti-Alzheimer agents. The results showed that most of the synthesized compounds exhibited high AChE inhibitory activity at the micromolar range (IC50, 0.46?12.09 &#956;M). The synthetic xanthone 11 showed the best inhibitory effect on AChE and a molecular modeling study revealed that 11 targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. Therefore, this compound could be considered as a potential lead compound towards new drugs for the treatment of Alzheimer´s disease.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242908,"idioma_id":4,"titulo":"Novel Class 1 Integrons and Sequence Types in VIM-2 and VIM-11- Producing Clinical Strains of Enterobacter cloacae","resumen":"All VIM-producing Enterobacteriaceae (six Enterobacter cloacae) submitted to the Argentinian Reference Laboratoryin Antimicrobial Resistance in the period 2008?13 were characterized. The isolates were referred from 6 nosocomialinstitutions located in 5 different cities across the country. All isolates showed carbapenem disk diffusioninhibition zones &#8804;22 mm and synergism between a carbapenem disk and EDTA\/SMA. The six isolates were PCRpositive for blaVIM. Imipenem MICs were &#8804;1 to 8 &#956;g\/ml. Typing by PFGE and MLST distinguished six pulsotypesand sequence types with blaVIM located on novel class 1 integron arrays: ECL-1: ST182, In883; ECL-2, ST90,In885; ECL-3, ST88, In346 with blaVIM-11; ECL-4, ST184, In900; ECL-5, ST749-new, In900; ECL-6, ST91 anduncharacterized In. Only ECL-2 was able to transfer blaVIM-2 to E. coli J53 by biparental conjugation. blaVIM was locatedin plasmids of 53?82 Kb and in the chromosome (ECL-1 and ECL-5). The diversity of clones, class 1integrons, plasmids and location of blaVIM, reveals the plasticity of the genetic elements described and highlightsthe importance of surveillance programs as tools to identify the transmission of these highly resistant metallo-&#946;-lactamase-producing Enterobacteriaceae.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242913,"idioma_id":5,"titulo":"El contexto en los estudios de psicología genética. Problemas y revisiones.","resumen":"Este artículo se propone discutir la noción de contexto en la psicología del desarrollo, comenzando por su  lugar en la obra de  Piaget y las modificaciones que han introducido diversos investigadores en el programa psicogenético. Así, se establecerá  cómo fue utilizada la noción de contexto en algunas investigaciones llevadas a  cabo a respecto de la intervención de representaciones sociales respecto de las operaciones y del juicio moral; así como la intervención de las prácticas sociales en la conceptualización del  derecho a la intimidad.   Se analizaran, a continuación, las diferentes maneras de caracterizar el contexto, desde las discusiones realizadas por autores neo vigotskyanos, y se  sugerirá  la tesis de que un contexto restringe o hace las veces de un catalizador para la construcción de los conocimientos. Se analizará   cuál es la  naturaleza misma del contexto, tematizándolo, e identificando su modo de intervención en las investigaciones: en las  ?unidades de análisis? y  la  entrevista.  Finalmente, se discutirá la distancia epistemológica que media entre un estudio constructivista en contexto respecto del contextualismo, en los estudios de cambio conceptual.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242915,"idioma_id":5,"titulo":"El problema de la interpretación del contexto en el estudio de los conocimientos infantiles en la antropología y la psicología constructivista*","resumen":"El artículo revisa el alcance y el significado de la categoría de contexto en la investigación psicológica y antropológica, con el fin de profundizar en el análisis de las relaciones entre la construcción de conocimiento infantil y el contexto en el que se lleva a cabo. Se exploran las dificultades meta-teóricas, teóricas y metodológicas que se presentan al analizar la definición del concepto y se sugieren modalidades de colaboración entre los campos de la antropología y la psicología constructivista, modificados a la luz de las reflexiones realizadas, para el estudio de las relaciones entre las construcciones de conocimiento y las prácticas sociales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242917,"idioma_id":4,"titulo":"Characterization of Streptococcus pneumoniae invasive serotype 19A isolates from Argentina (1993&ndash;2014)","resumen":"The aim of this study was to characterize Streptococcus pneumoniae serotype 19A isolates causing invasivepneumococcal disease in children, collected in Argentina between 1993 and 2014. A total of 176 isolatesserotype 19A were analyzed. There was an increase in the proportion of serotype 19A isolates from 3% in1993 to 6% in 2011, prior to the introduction of PCV13 in 2012, and from 2012 to 2014 its proportiongradually decreased.Penicillin resistance among serotype 19A isolates throughout the study period was 65.9%, but a significantincrease was observed from 0% in 1993 to 87.5% in 2014. Genetic relationship of the isolates wasdetermined by PFGE and selected strains were studied by MLST. Most of the isolates belonged to two clonaltypes: A (54.5%) and B (11.4%). Isolates of clonal type A were ST1131, a single locus variant of ST172and accounted for 54% of the total collection. They were detected for the first time in our country in 1997and most of them (93%) were penicillin non susceptible. Isolates of clonal type B were ST8121, a singlelocus variant of ST199, and were mainly susceptible to penicillin. These two clonal types are still in circulationand appear to be responsible for the dissemination of S. pneumoniae serotype 19A invasive isolatesin our country.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242918,"idioma_id":4,"titulo":"Prevalence of Plasmid-Mediated Quinolone Resistance Genes in Clinical Enterobacteria from Argentina","resumen":"This first nationwide study was conducted to analyze the prevalence of plasmid-mediated quinolone resistance(PMQR) genes in phenotypically unselected (consecutive) clinical enterobacteria. We studied 1,058 isolatesthat had been consecutively collected in 66 hospitals of the WHONET-Argentina Resistance SurveillanceNetwork. Overall, 26% of isolates were nonsusceptible to at least one of the three quinolones tested (nalidixicacid, ciprofloxacin, and levofloxacin). The overall prevalence of PMQR genes was 8.1% (4.6% for aac(6¢)-Ibcr;3.9% for qnr genes; and 0.4% for oqxA and oqxB, which were not previously reported in enterobacteria otherthan Klebsiella spp. from Argentina). The PMQR prevalence was highly variable among the enterobacterialspecies or when the different genes were considered. The prevalent PMQR genes were located in class 1integrons [qnrB2, qnrB10, and aac(6¢)-Ib-cr]; in the ColE1-type plasmid pPAB19-1 or Tn2012-like transposons(qnrB19); and in Tn6238 or bracketed by IS26 and blaOXA-1 [aac(6¢)-Ib-cr]. The mutations associated withquinolone resistance that were located in the quinolone resistance-determining region (QRDR mutations) ofgyrA, parC, and gyrB were also investigated. The occurrence of QRDR mutations was significantly associatedwith the presence of PMQR genes: At least one QRDR mutation was present in 82% of the PMQR-harboringisolates but in only 23% of those without PMQR genes ( p < 0.0001, Fisher?s Test). To the best of ourknowledge, this is the first report on the prevalence of PMQR genes in consecutive clinical enterobacteria whereall the genes currently known have been screened.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242919,"idioma_id":4,"titulo":"Molecular Genetic Profiling of Clinical and Foodborne Strains of Enterococci with High Level Resistance to Gentamicin and Vancomycin","resumen":"Enterococci often acquire antimicrobial resistance through horizontal gene transfer. Relatedness betweenenterococci with high level resistance to gentamicin and vancomycin isolated from humans, food and hospitalenvironment in Tandil County (Argentina) was investigated. PCR amplification for species determination was carriedout. Resistance to seven antimicrobials was studied; virulence genes (esp, cylA), vancomycin and gentamicinresistance genes were investigated. In the isolates with high level antimicrobial resistance (gentamicin, vancomycin),pulse-field gel electrophoresis was performed. Vancomycin-resistant E. faecium (n:13) were recovered from human,food and hospital environment samples. All the isolates expressed high-level vancomycin and teicoplanin (vanAgenotype), as well high-level gentamicin and streptomycin resistance. Vancomycin-resistant E. faecium weredistributed among seven clonal types; esp gene was detected in clinical strains. There was no clonal relationshipwith food vanA E. faecium, but these strains could pose a risk in intra\/inter genus transfer of vanA determinant tohuman-adapted strains. High-level gentamicin resistant E. faecalis (n:7) were recovered from human and foodsamples. Glycopeptide resistance was not observed; cylA gene was detected in most of the clinical high-levelgentamicin resistant E. faecalis isolates. PFGE patterns showed four clonal types in high-level gentamicin resistantE. faecalis strains; there was demonstrated clonal relatedness between isolates from different origin. In Argentina,this is the first study showing a clonal relationship between high-level gentamicin resistant E. faecalis isolated fromfood and humans. These results encourage the study of dissemination of clonal complexes with mobile resistancegenes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242927,"idioma_id":4,"titulo":"Spray drying encapsulation of red wine: Stability of total monomeric anthocyanins and structural alterations upon storage","resumen":"Wine C. Sauvignon was encapsulated by spray drying to obtain a wine powder having a low water activity (aw). Maltodextrin DE10 was added to wine before atomization. The retention of Total Monomeric Anthocyanins (TMA) in the wine powder was found to be above 83%. Wine powder was stored under various relative humidities, and TMA concentration was determined up to 120days at 38ºC. Anthocyanins decreased steadily during storage and increasing RH% enhanced the losses. Results stressed the importance of aw (or RH%) as a key control parameter for anthocyanins stability during storage. Encapsulated wine collapsed when exposed few days to 58% RH and 38ºC; this was investigated by spray drying wine model systems containing various nonvolatilecomponents of the dry extract, namely glycerol, organic acids, and monosaccharides. Structural alterations of encapsulated wine were attributed to glycerol, main component of dry extract and which has a very low glass transition temperature.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242928,"idioma_id":5,"titulo":"Represión a trabajadores\/as y responsabilidad empresarial en la Región Gran La Plata durante el terrorismo de Estado.","resumen":"Este artículo se propone una caracterización de la responsabilidad empresarial en la represión a trabajadores y trabajadoras durante el terrorismo de Estado en la región Gran La Plata, sur del cordón industrial bonaerense, que comprende las ciudades de La Plata, Berisso y Ensenada, donde se encuentran radicadas importantes empresas industriales. Parte del análisis de 4 grandes empresas industriales, estatal y privadas: Astillero Rio Santiago, Frigorífico Swift, Petroquímica Sudamericana y Propulsora Siderúrgica, donde la responsabilidad empresarial será analizada desde aquellos aspectos más generales de la dinámica represiva en la región hasta hechos muy concretos que indican su participación en la represión. Asimismo, pondrá de relieve especialmente que este proceso tuvo como objetivo de eliminar al sector de la clase obrera más combativo y que había alcanzado cada vez mayores grados de organización.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242929,"idioma_id":5,"titulo":"Tercerización laboral, salario por tiempo y precarización en la industria siderúrgica. El caso de Siderar, Ensenada. Revista Latinoamericana de Antropología del Trabajo","resumen":"La tercerización laboral en la industria se extendió fuertemente a partir de los años 90 adquiriendo distintas modalidades tendientes a una precarización de la fuerza de trabajo y a la transferencia de responsabilidades hacia las empresas tercerizadas y, en muchos casos, a los propios trabajadores\/as sobre sus condiciones salariales, de trabajo y salud. Este artículo analiza las modalidades salariales veladas a partir de la firma de contratos comerciales entre empresas partiendo de un estudio de caso, en la industria siderúrgica argentina que relevó la experiencias de 6 pequeñas empresas de ex trabajadores, tercerizadas por Siderar Sociedad Anónima (Siderar S:A), perteneciente al complejo Ternium del Grupo Techint. desde principios de la década del 90. La investigación se realizó desde una perspectiva etnográfica, que permitió abordar las profundas relaciones de explotación y dependencia, que ocultan modalidades de salario por tiempo, bajo la apariencia de relaciones comerciales entre empresas 'clientes' y empresas 'proveedoras'.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242935,"idioma_id":5,"titulo":"Evolución Temporal de Sequías Hidrológicas en Argentina y su Relación con Indicadores Macroclimáticos","resumen":"En este trabajo se identifican, a través de un análisis espectral, las periodicidades plurianuales en las series históricas de caudales medios anuales escurridos en 14 sistemas fluviales de la República Argentina y en 10 indicadores macroclimáticos. La identificación de las frecuencias de tiempo dominantes en las series de caudales escurridos permite comprender la escala temporal de evolución de los procesos físicos que intervienen en los ciclos hidrológicos.En el análisis realizado se encontró que existe en todas las series históricas de caudales medios anuales escurridos, fluctuaciones de alta, baja y media frecuencia que aportan, con distinta significancia, a la variabilidad temporal de los caudales escurridos. Luego estos resultados se contrastaron con los obtenidos en el análisis de series de indicadores macroclimaticos para saber si existe relación de la evolución de estos indicadores con las series de caudales. Los resultados alcanzados permiten avanzar en la generación de modelos conceptuales y de pronósticos implementados paraprever los años de déficit y excesos hídricos en sistemas fluviales, lo que constituyen una herramienta importante para laplanificación y gestión de los recursos hídricos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242936,"idioma_id":4,"titulo":"Contracting montane cloud forests: a case study of the Andean alder (Alnus&nbsp;acuminata) and associated fungi in the Yungas","resumen":"Alnus acuminata is a keystone tree species in the Yungas forests and host to a wide range of fungal symbionts. While species distribution models (SDMs) are routinely used for plants and animals to study the effects of climate change on montane forest communities, employing SDMs in fungi has been hindered by the lack of data on their geographic distribution. The well-known host specificity and common biogeographic history of A.&nbsp;acuminata and associated ectomycorrhizal (ECM) fungi provide an exceptional opportunity to model the potential habitat for this symbiotic assemblage and to predict possible climate-driven changes in the future. We (1) modeled the present and future distributions of suitable habitats for A.&nbsp;acuminata; (2) characterized fungal communities in different altitudinal zones of the Yungas using DNA metabarcoding of soil and root samples; and (3) selected fungi that were significant indicators of Alnus. Fungal communities were strongly structured according to altitudinal forest types and the presence of Alnus. Fungal indicators of Alnus, particularly ECM and root endophytic fungi, were also detected in Alnus roots. Current and future (year 2050) habitat models developed for A.&nbsp;acuminata predict a 25&ndash;50 percent decrease in suitable area and an upslope shift of the suitable habitat by ca. 184&ndash;380&nbsp;m, depending on the climate change scenario. Although A.&nbsp;acuminata is considered to be an effective disperser, recent studies suggest that Andean grasslands are remarkably resistant to forest invasion, and future range contraction for A.&nbsp;acuminata may be even more pronounced than predicted by our models.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242937,"idioma_id":4,"titulo":"Hypogeous sequestrate fungi in South America &ndash; how well do we know them?","resumen":"Collecting and studying hypogeous sequestrate fungi and their particular fruiting biology has always been challenging and intriguing for scientists. However, knowledge of hypogeous taxa has for a long time been limited mainly to the Northern Hemisphere, and more recently, Australia. Nevertheless, cumulative information on sequestrate fungi for South America (SA) has increased considerably over the years, and constitutes by itself, the aim of this review. We have reviewed the available published literature, from 1880 until recent times, to extract information on records, ecology, and morphological characteristics of hypogeous sequestrate fungi from SA. Based on the 172 taxa cited in the available literature, a trend of increasing interest in the study of these fungi in the region is apparent, yet with an uneven distribution among countries, climate belts, and nature of forest habitats. Hypogeous truffle-like species in SA play a key role in regulating nutrient and carbon cycles and in all ecosystem multifunctionality. The symbiotic status is provided for most species listed, and mutualism, especially ectomycorrhizal, is predominant (82 %). The hypogeous sequestrate fungi in SA are an understudied group of fungi, with exceptional anatomical and biological features as well as in many cases intriguing phylogenetic relationships, requiring more attention and analysis from mycologists.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242939,"idioma_id":4,"titulo":"Mycophagy by invasive wild boar (Sus scrofa) facilitates dispersal of native and introduced mycorrhizal fungi in Patagonia, Argentina","resumen":"Fleshy hypogeous fungi produce scents that enable mycophagous mammals and invertebrates to locate them and disperse their spores. The European wild boar (Sus scrofa) was introduced in central Argentina in 1900s and later expanded into Patagonia. Here, we determined the diversity and abundance of fungal taxa, and the frequency of hypogeous fungal spores in wild boar feces in Patagonia. We collected fecal samples on Isla Victoria, Nahuel Huapi National Park, and identified fungi using microscope and DNA metabarcoding of ITS2 rDNA. Hypogeous fungal spores occurred in almost all fecal samples. The most abundant species belonged to the genera Hysterangium, Melanogaster, Radiigera and Gautieria. In addition to the symbiotrophic hypogeous taxa, we also identified numerous pathotrophic and saprotrophic taxa. Not only diverse native hypogeous fungi, but also introduced ones are part of the diet of the wild boar in forests of Patagonia. If viable, introduced fungi are being dispersed as far as 2.5 km from the nearest plantation, highlighting how the introduced wild boar might alter the local distribution and composition of fungal communities.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242940,"idioma_id":4,"titulo":"A molecular and morphological re-examination of the generic limits of truffles in the tarzetta-geopyxis lineage &ndash; Densocarpa, Hydnocystis, and Paurocotylis","resumen":"Truffle species within the \/tarzetta-geopyxis lineage share smooth, globose, hyaline spores, but differ in the amount of convolution of hymenia in ascomata. The relationships among truffle species in this lineage have historically been confused. Phylogenetic analyses of the ITS and 28S nuclear ribosomal DNA from recently collected members of the \/tarzetta-geopyxis lineage from Asia, Austral Asia, North America, and South America prompted a reinvestigation of species and generic limits in the truffle genera Hydnocystis, Paurocotylis, and Stephensia. Our analyses support emendations of Hydnocystis and Paurocotylis, abandonment of Stephensia and the resurrection of the genus Densocarpa. Nomenclatural changes include the transfer of Stephensia bombycina to Hydnocystis, the transfer of Hydnocystis singeri and Stephensia bynumii to Paurocotylis, the reinstatement of Densocarpa for Stephensia shanori and transfer of Stephensia crocea to Densocarpa. This is the first detection of the genus Paurocotylis in the Americas. We describe three new species, Hydnocystis transitoria from North America, Paurocotylis patagonica from South America, and Paurocotylis watlingii from Australia. Our work highlights the unexplored diversity, morphological plasticity, and remaining taxonomic problems among truffles in the \/tarzetta-geopyxis lineage.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242941,"idioma_id":4,"titulo":"HOW TO KNOW THE FUNGI: COMBINING FIELD INVENTORIES AND DNA-BARCODING TO DOCUMENT FUNGAL DIVERSITY","resumen":"The Southern Hemisphere harbors many unique fungal lineagesthat are absent from the Northern Hemisphere (Tedersoo&Smith,2013; Tedersoo et al., 2014). In southern South America, recentstudies based on environmental sequences have detected severalpreviously unknown fungal lineages, thereby demonstrating thatfungal diversity is probably much higher than presently known(Nouhra et al., 2013; Geml et al., 2014; Roy et al., 2017).As part of a project investigating ectomycorrhizal (ECM) fungiof southern South America, our team collected 1430 fungal fruitingbodies during four collecting expeditions, equaling c. 50 d with 3?4collectors per day (Supporting Information Methods S1). Weprimarily collected ECM fungi in temperate forests dominated byNothofagaceae but also opportunistically collected nonECMfungi. Vouchered specimens were photographed and dried forfuture study. Internal transcribed spacerrDNAsequences (ITS, e.g.ITS1-5.8S-ITS2) were obtained from a representative selection of957 specimens using the Extract-N-AmpPlant kit (Sigma-Aldrich)for rapid DNA extraction and amplification. ITS sequences wereclustered into operational taxonomic units (OTUs) at 97?99%similarity against the UNITE ?species hypothesis? dynamicdatabase (Abarenkov et al., 2010a; K~oljalg et al., 2013) usingQIIME 1.9.1 (Caporaso et al., 2010). Sequences that did notcorrespond to an existing ?species hypothesis? in the referencedatabase were subsequently clustered de novo at 97% similarity(Methods S1). One representative sequence per OTU wassubsequently compared to UNITE+INSD (UNITE and theInternational Nucleotide Sequence Databases) using MEGABLASTon the PLUTOF workbench (Abarenkov et al., 2010b).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242942,"idioma_id":4,"titulo":"A systematic overview of Descolea ( Agaricales ) in the Nothofagaceae forests of Patagonia","resumen":"The descolea clade includes species of ectomycorrhizal basidiomycetes in the genera Descolea, Setchelliogaster, Descomyces, and Timgrovea that are known primarily from the Southern Hemisphere. Taxa in this group produce basidiomes that range in morphology from typical epigeous mushrooms (Descolea) and secotioid taxa (Setchelliogaster) to fully gasteroid species (Descomyces and Timgrovea). High intraspecific morphological variation has been reported in several species within this clade, suggesting that careful morphological and molecular studies are needed to refine species concepts. Molecular analyses of fresh Patagonian collections in conjunction with taxonomic studies have confirmed high variability in key morphological features, including overall sporocarp form, spore shape and dimensions, universal veil remnants, and cuticle configuration. Based on our synthesis, we emend the genus Descolea to include sequestrate species. We describe the new sequestrate taxon Descolea inferna sp. nov. from Nothofagaceae forests in Patagonia and we propose Cortinarius squamatus as a synonym of our new combination Descolea brunnea. We also formalize the identity of Descolea pallida as a synonym of Descolea antarctica and provide new specimens of Cortinarius archeuretus, a species that has not been encountered since the original discovery during the expeditions of Roland Thaxter in 1905?1906. Here we re-describe and transfer this species to Descolea as D. archeureta. We also discuss diagnostic features that can be used to delimitate the four known South American taxa in the descolea clade.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242943,"idioma_id":4,"titulo":"Pseudotricharina lanigera (Pezizales), a new species from the Patagonian region of Argentina","resumen":"species of Pseudotricharina, similar in sequence and morphology to the type species P. intermedia,is described from a soil bank in a Nothofagus forest of the Andes Mountains of Argentina. This is only the secondspecies of Pseudotricharina to be described and the first known from the Southern Hemisphere.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242944,"idioma_id":4,"titulo":"Nebulizing novel multifunctional nanovesicles: the impact of macrophage-targeted-pH-sensitive archaeosomes on a pulmonary surfactant","resumen":"In this study, a NE-U22 vibrating mesh Omron nebulizer was used to deliver the Lissaminet rhodamine B 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine triethylammonium salt (Rh-PE) and 8-hydroxypyrene-1,3,6-trisulfonic acid trisodium salt (HPTS)\/p-xylene-bis-pyridinium bromide (DPX)double-labelled macrophage-targeted pH-sensitive archaeosomes (ApH, 174 _ 48 nm, _30 _ 13 mV unilamellar nanovesicles made of dioleoyl-sn-glycero-3-phosphoethanolamine: [total polar archaeolipids from the hyperhalophile archaebacteria Halorubrum tebenquichense]: cholesteryl hemisuccinate 4.2 : 2.8 : 3 w:w: w) to J774A.1 cells covered by a Prosurf pulmonary surfactant (PS) monolayer at or below the equilibrium surface pressure pe. The uptake and cytoplasmic drug release from ApH were assessed by flow cytometry of Rh-PE and HPTS fluorescence, respectively. Despite being soft matter, nanovesicles are submitted to the dismantling interactions of shear stress of nebulization and contact with the surfactant barrier, and at least a fraction of nebulized ApH was found to be stable enough to execute higher cytoplasmic delivery than archaeolipid-lacking vesicles. Nebulized ApH increased the PS tensioactivity to just below pe, which was beyond the physiological range; this finding indicated that changes in lung surfactant function induced by nebulized nanovesicles were less likely to occur in vivo. The cytoplasmic delivery from ApH slightly decreased across monolayers at pe; this suggested that nanovesicles crossed the PS in a fashion inversely related to monolayer compression.Laurdan generalized polarization and fluorescence anisotropy were used to reveal that nanovesicles neither depleted B and C proteins of the PS nor increased the fluidity of the PS. Together with the feasibility of the cytoplasmic drug delivery upon nebulization, our results suggest that ApH are structurally unique nanovesicles that would not induce biophysical changes leading to PS inactivation and open the door to deeper future translational studies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242948,"idioma_id":4,"titulo":"Adsorption of laterally interacting gas mixtures on homogeneous surfaces","resumen":"The adsorption of binary mixtures containing particles A and B on homogeneous substrates is studied by Monte Carlo (MC) simulations, quasi-chemical approximation (QCA), and exact counting of states on nite cells (we call this approach cluster approximation, CA). The energies involved in the adsorption model are ve: 1) A, interaction energy between a A particle and a lattice site; 2) B, interaction energy between a B particle and a lattice site; 3) wAA, nearest-neighbor interaction energy between two A particles; 4) wAB (=wBA), nearest-neighbor interaction energy between a A particle and a B particle and 5) wBB, nearest-neighbor interaction energy between two B particles.The process is monitored by following the coverage of both species with the simultaneous increasing of the individual chemical potentials of each mixture component. A non-trivial interdependence between the partial adsorption isotherms was observed and discussed in the context of the latticegas theory. The theoretical formalism is used to model experimental data of methane-carbon dioxide mixtures adsorbed on activated carbon. In addition, an excellent agreement was obtained between theoretical and MC simulation results. This nding evidences the usefulness of CA and QCA as a starting point to predict the behavior of a system governed by a large number of parameters.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242949,"idioma_id":4,"titulo":"Protonation of &beta;-lactoglobulin in the presence of strong polyelectrolyte chains: A study using Monte Carlo simulation","resumen":"In this work, the molecular interaction between the protein &#946;-lactoglobulin and strong polyelectrolyte chains was studied using Monte Carlo simulations. Different coarse-grained models were used to represent the system components. Both net charge and protonation of the isolated dimeric protein were analyzed as a function of pH. The acid-base equilibrium of each titratable group was distinctively modified by the presence of polyanion or polycation chains. The complexation on the wrong side of pI was more evident with the polycation than with the polyanion. It was mainly due to a charge regulation mechanism, where the reversion in net charge of the protein was more pronounced at the left of isoelectric point of the protein. The glutamic and aspartic groups play a key role in this charge reversion. Both polyanion and polycation were spatially adsorbed in different region on the protein surface, suggesting the importance of the surface charge distribution of the protein.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242953,"idioma_id":5,"titulo":"Implantes de zirconio y\/o PEEK como recurso en discapacitados sociales y funcionales orales","resumen":"Durante muchos años se ha intentado conseguir una solución estética al problema de los desdentados parciales,que presentan psicológicos que llevan a los pacientes a cambiar los hábitos para hablar, gesticular y sonreír. En este sentido, los implantes dentarios pueden ser una solución que plantea la asignatura de Prótesis B de la Facultad de Odontología de la UNLP. El objetivo de este trabajo es proporcionar un tratamiento pórético  a los pacientes discapacitados sociales mediante la colocación de implantes dentarios de zirconio y\/o PEEK.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242956,"idioma_id":5,"titulo":"ACERCANDO LAS ENERGÍAS RENOVABLES A LA COMUNIDAD. INSTALACIÓN DE CARGADORES SOLARES PARA DISPOSITIVOS MÓVILES EN LA REGIÓN NEA","resumen":"El presente trabajo expone los resultados de la transferencia tecnológica y puesta en funcionamiento de un mobiliario urbano innovador, denominado ?Cargador Solar para dispositivos móviles? en distintos sitios urbanos y turísticos de la Región Nordeste Argentina (NEA).Se trata de un dispositivo multipropósito (cargador de celulares, artefacto de luz, hito urbano) que brinda un servicio público y a la vez actúa como medio de difusión de la conciencia ecológica y la necesidad de incorporar las energías renovables a la vida cotidiana. Su diseño ha sido realizado por un equipo interdisciplinario de docentes ? investigadores de la Universidad Nacional del Nordeste.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242958,"idioma_id":5,"titulo":"Representaciones sociales sobre dengue de docentes de Argentina en dos contextos epidemiológicos: aportes para la formación docente","resumen":"Entendemos al dengue como una problemática compleja de salud socioambiental. Considerada la enfermedad viral transmitida por artrópodos de mayor importancia en el mundo, se ha instalado en la Argentina con gran significatividad social y epidemiológica, especialmente en periodos epidémicos. Durante este año, 2016, oficialmente se registraron alrededor de 40.000 casos (la mayor cantidad de la historia) y la problemática tuvo un intenso tratamiento en los medios de comunicación. En el marco de un abordaje de la problemática desde la investigación educativa, basándonos en información empírica obtenida en talleres de formación, realizamos un análisis de representaciones sociales de docentes de primaria. Los procesos de formación docente fueron implementados en dos provincias de Argentina, una con baja incidencia de casos y otra con altos niveles de transmisión. En los resultados identificamos un patrón común, constituido por un sesgo inicial hacia la dimensión biomédica, siendo el mosquito y los síntomas, entre otras, las primeras imágenes más fuertemente asociadas al dengue. Esto resultó un punto de partida a partir del cual, luego del trabajo grupal en los talleres, emergieron con más fuerza otras dimensiones, destacándose particularmente la política y, en menor medida, la sociocultural, relacionada con la información y su circulación social. Finalmente, en las actividades elaboradas para desarrollar en los contextos educativos de cada docente, identificamos una gran frecuencia de propuestas vinculadas principalmente con la difusión en las que solamente aparecían las dimensiones biomédica y sociocultural, prácticamente con igual peso. Inferimos que las representaciones de las\/os docentes tendrían un núcleo central compuesto principalmente por nociones biomédicas mientras que la multidimensionalidad, que incorpora nociones políticas, socioculturales y otras, serían parte de la periferia, que, en el caso del contexto de alta transmisión, tendría un mayor peso relativo. La posibilidad de poner en juego esta periferia en los talleres, habría estado facilitada por el abordaje didáctico construido a partir del trabajo grupal y el posicionamiento en diferentes roles sociales. Los resultados obtenidos sugieren el desafío de continuar la línea de trabajo en pos de desarrollar espacios de formación que fomenten enfoques educativos más críticos y transformadores.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242959,"idioma_id":5,"titulo":"Formación docente y representaciones sobre salud: caminos para la educación en salud desde una mirada crítica","resumen":"Con el objetivo de realizar un aporte a la formación docente, presentamos un análisis de representaciones sobre salud a partir de definiciones y producciones gráficas en el marco de una experiencia pedagógica para docentes en ejercicio del nivel inicial, realizada entre 2012 y 2014. Las definiciones permitieron reconocer las ontologías subyacentes, mientras que las producciones gráficas desplegaron variados componentes y dimensiones, enriqueciendo a las definiciones. Identificamos una lectura de la salud centrada en el individuo, que relacionamos con categorías de trabajos anteriores como la salud como estilo de vida, la salud como equilibrio y el enfoque educativo comportamental. La reflexión crítica respecto de las prácticas asociadas a esta mirada fue, en nuestra experiencia, una de las puertas de entrada para desnaturalizar lo existente y fomentar perspectivas más complejas, multidimensionales y críticas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242960,"idioma_id":5,"titulo":"Análisis de materiales didácticos e informativos sobre dengue en Argentina","resumen":"Presentamos un análisis de materiales didácticos e informativos sobre dengue, elaborados por Ministerios de Salud y Educación de diferentes jurisdicciones de Argentina. Realizamos un análisis de contenido indagando dimensiones de la salud, modelos didácticos, modelos epidemiológicos y concepciones acerca de participación. Inferimos que la perspectiva dominante tuvo una fuerte impronta biomédica, desde un modelo epidemiológico lineal multicausal. El eje principal fue el ?manejo de criaderos?,  acciones para reducir los recipientes domésticos con agua en los que se cría el mosquito Aedes aegypti. Si bien la participación de la comunidad apareció como central, la concepción subyacente fue de pseudoparticipación (la comunidad como ejecutora de recomendaciones, sin injerencia en las decisiones). Finalmente, si bien en las fundamentaciones de las propuestas didácticas inferimos una intencionalidad constructivista, en la mayoría de las actividades identificamos un modelo de transmisión-recepción.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242968,"idioma_id":5,"titulo":"El Artículo 65: el impacto de la cuota de música nacional en las radios de Argentina.","resumen":"En el año 2009 tuvo lugar en la Argentina un proceso regulatorio para los servicios de comunicación audiovisual. En ese marco, el artículo 65 establece las cuotas de música nacional y nacional independiente que deben incluir las estaciones de radio en sus contenidos. En el presente trabajo se lleva a cabo un análisis sobre el nivel de cumplimiento de dicha normativa por las seis radios con mayor rating del país en distintos periodos, buscando así determinar si el proceso regulatorio ha tenido algún grado de impacto en la programación musical de las radios.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242982,"idioma_id":5,"titulo":"FIRST GRID-TIED PHOTOVOLTAIC SYSTEM IN NOTRHERN ARGENTINA: CHARACTERIZATION AND ANALYSIS","resumen":"A 600 Wp grid-tied photovoltaic system (GCFV) was designedand installed by the Renewable Energy Group (GER) in orderto study the effects on the low voltage distribution network.The system was installed at the Physics building of theFacultad de Ciencias Exactas y Naturales in the city ofCorrientes, Argentina. The system is injecting the generatedenergy to the low voltage network since 2010 and has beenmonitored thenceforth using different measuring instruments.System features, the methodology adopted to characterize thequality and quantity of energy injected and the evaluation ofperformance characteristics (according to IEC 61724standard) for the period between january 2011 and dicember2012 are all topics presented in this article. The Grid TiedFotovoltaic System generates a monthly average of activepower of about 56 kWh with a current Total HarmonicDistortion lower than 10%, an average power factor equal to0.93 and an average efficiency in the DC\/AC conversion stageequal to 89.4%. During the first 10 months of 2011, changes inthe performance ratio (PR) of the system are comparable tothose reported in literature for other systems, however duringthe remaining months the PR decreased due to instabilities inthe network parameters. It is concluded that systems withthese characteristics can efficiently and safely be used toimplement Distributed Generation in Northern Argentinaregion, being able to improve the quality and supply capacityin the local network as long as inverters suitable to operate onnetworks presenting instabilities in their characteristicparameters are used.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242983,"idioma_id":4,"titulo":"Ionic liquid-assisted separation and determination of selenium species in food and beverage samples by liquid chromatography coupled to hydride generation atomic fluorescence spectrometry","resumen":"Different ionic liquids (ILs) were assayed as mobile phase modifiers for the separation and determination of selenite [Se(IV)], selenate [Se(VI)], selenomethionine (SeMet) and Se-methylselenocysteine (SeMeSeCys) by reversed-phase high-performance liquid chromatography coupled to hydride generation atomic fluorescence spectrometry (RP-HPLC-HG-AFS). The use of several ILs: 1-butyl-3-methylimidazolium chloride, 1-hexyl-3-methylimidazolium chloride ([C6mim]Cl), 1-octyl-3-methylimidazolium chloride, 1-dodecyl-3-methylimidazolium bromide, 1-hexadecyl-3-methylimidazolium bromide and tributyl(methyl)phosphonium methylsulphate was evaluated. Also, the effect of pH, buffer type and IL concentration on the separation of Se species was studied. Complete separation was attained within 12 min using a C8 column and a gradient performed with a mobile phase containing 0.1% (v\/v) [C6mim]Cl at pH 6.0. The proposed method allows the separation of inorganic and organic Se species in a single chromatographic run, adding further benefits over already reported methods based on RP-HPLC. In addition, the influence of ILs on the AFS signals of each Se species was evaluated and a multivariate methodology was used for optimization of AFS sensitivity. The limits of detection were 0.92, 0.86, 1.41 and 1.19 µg L-1 for Se(IV), Se(VI), SeMet and SeMeSeCys, respectively. The method was successfully applied for speciation analysis of Se in complex samples, such as wine, beer, yeast and garlic.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242984,"idioma_id":4,"titulo":"Synthesis of magnetic polymeric ionic liquid nanocomposites by the Radziszewski reaction","resumen":"In the present article a new approach for the synthesis of magnetic polymeric ionic liquid nanocomposites based on the Radziszewski reaction is presented. The Radziszewski reaction is a simple and successful procedure to obtain imidazolium-containing polymers under mild conditions and consists of the reaction between diamine compounds, glyoxal and formaldehyde in an acidic media. If magnetic nanoparticles coated with amino groups are introduced, they can participate as polyamines in the synthesis thus providing a final nanocomposite where polymeric ionic liquids and nanoparticles are combined. The resulting nanocomposite has been characterized using several instrumental techniques aimed at elucidating its chemical composition (infrared spectroscopy and elemental analysis), properties (zeta potential) and morphology (microscopy, X-ray diffraction and dynamic light scattering). Finally, its sorptive ability towards three non-steroidal anti-inflammatory drugs (NSAIDs) such as salicylic acid, ketoprofen and naproxen was evaluated considering the main variables involved in the process. According to the results, the polymeric ionic liquid nanocomposite is a promising sorptive material for analytical purposes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242985,"idioma_id":4,"titulo":"Synergistic analytical preconcentration with ionic liquid-nanomaterial hybrids","resumen":"Nanomaterials and ionic liquids (ILs) have very attractive properties for improved analytical preconcentration methods. Thus, ILs have been used as excellent tools to functionalize nanomaterials, giving them specific chemical properties for higher selectivity, extraction efficiency and extended re-utilization in preconcentration. Moreover, incorporation of IL-nanomaterial hybrids in miniaturized solid phase and liquid phase microextraction procedures is being increasingly exploited to obtain high analytical recoveries while developing environmentally friendly analytical methods. In this review, the design and application of innovative and efficient analytical methods for sensitive and selective determination of inorganic and organic analytes is described. The synthesis of some IL-nanomaterial hybrids is presented along with a revision of the most important synergistic physicochemical properties useful for the extraction of analytes. Finally, practical considerations concerning the application of IL-nanomaterial hybrids for the development of modern analytical separation and preconcentration techniques are fully discussed in this work.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242989,"idioma_id":4,"titulo":"Middle Triassic trachytic lava flows associated with coeval dyke swarm in the North Patagonian Massif: A postorogenic magmatism related to extensional collapse of the Gondwanide orogen","resumen":"The Marifil Volcanic Complex is an extended volcanic and pyroclastic unit outcropping in the North Patagonia. It has been included in the Chon Aike large igneous province associated to the thermal anomaly of the Karoo plume. The Marifil Volcanic Complex is mainly composed of rhyolites, dacites, rhyodacites and minor trachytes and trachyandesites. The latter are common in the base of the unit. The upper acidic rocks have been dated between 192 Ma to 151 Ma (Early to Middle Jurassic) by K-Ar, Ar-Ar and Rb-Sr methods. On the other hand, the age of the mesosilicic rocks range from 221 Ma to 173 Ma (K-Ar whole rock ages). In this research, we revise the stratigraphic relations, geochemistry and petrography of the mesosilisic rocks from Marifil Volcanic Complex. Aditionally, a new UPb crystallization age of 247.22 ± 0.46 Ma was obtained for an trachytic lava flow that covers Permian granitoids and which is covered by rhyolitic ignimbrites. The mentioned mesosilisic rocks are chemically trachytes andtrachyandesites and show subduction margin affinities. In the area, a Triassic trachyandesitic dyke swarm has been considered as an expression of Gondwanide postorogenic extension in the North Patagonian Massif. Basis on our newage data and considering the compositional and stratigraphic differences we separate the Triassic trachytic to trachyandesitic rocks from the Jurassic rhyolites and dacites. These two groups of rocks represent different geotectonic events in the Southwestern margin of Pangea.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242990,"idioma_id":4,"titulo":"The Nahuel Niyeu basin: A Cambrian forearc basin in the eastern North Patagonian Massif","resumen":"Early Paleozoic basement of the eastern North Patagonian Massif includes low- and high grade metamorphic units, which consist mainly of alternating paraderived metamorphic rocks (mostly derived from siliciclastic protoliths) with minor intercalations of orthoderived metamorphic rocks. In this contribution we provide a better understanding of the tectonic setting in which the protoliths of these units were formed, which adds to an earlier suggested idea. With this purpose, we studied the metasedimentary rocks of the low-grade Nahuel Niyeu Formation from the Aguada Cecilio area combining mapping and petrographic analysis with UePb geochronology and characterization of detrital zircon grains. The results and interpretations of this unit, together with published geological, geochronological and geochemicalinformation, allow us to interpret the sedimentary and igneous protoliths of all metamorphic units from the massif as formed in a forearc basin at ~520e510 Ma (Nahuel Niyeu basin). It probably was elongated in the ~NWeSE direction, and would have received detritus from a proximal source area situated toward its northeastern side (present coordinates). The basin might be related to an extensional tectonic regime. Most likely source rocks were: (1) 520-510 Ma, acidic volcanic rocks (an active magmatic arc), (2) ~555->520 Ma, acidic plutonic and volcanic rocks (earlier stages of the same arc), and (3) latest Ediacaran-Terreneuvian, paraderived metamorphic rocks (country rocks of the arc). We evaluate the Nahuel Niyeu basin considering the eastern North Patagonian Massif as an autochthonous part of South America, adding to the discussion of the origin of Patagonia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242991,"idioma_id":4,"titulo":"Obtention and characterization of dried gels prepared with whey proteins, honey and hydrocolloids mixture","resumen":"BACKGROUND: Large amounts of honey and liquid whey derived from the dairy industry are produced in Argentina. Honey is exported in bulk and whey is transformed into whey protein concentrates and isolates. The objective of this work was to investigate the effect of pH, composition and storage time on the properties of dried gels with honey, whey proteins and hydrocolloids. RESULTS: Color properties varied according to pH and composition. The fracture stress of dried gels prepared with corn starch was higher than that of gels prepared with guar gum in all conditions assayed. Young´s modulus was higher at pH 7 for both compositions and increased with storage time. Rubbery characteristics were found in dried gels with guar gum, while both corn starch and guar gum made the microstructure rougher. Multivariate analysis showed that samples could be grouped by pH. Panelists preferred pH 7 products over acidic ones, and no significant differences in sensory properties were found using either corn starch or guar gum in the formulation. CONCLUSION: The results demonstrated that it is possible to generate a new product, which may open new applications for honey and whey in food formulations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242992,"idioma_id":4,"titulo":"Potential of nanostructured alumina for leaf-cutting ants Acromyrmex lobicornis (Hymenoptera: Formicidae) management","resumen":"The present study assessed the contact toxicity of nanostructured alumina (NSA) and compared it to that of diatomaceousearth (DE) on workers of Acromyrmex lobicornis. Laboratory and field bioassays were also conducted toassess whether ants avoid NSA particles. Nanostructured alumina was more toxic to ants than DE (LC50 forNSA = 0.14 mg\/g; CI 0.12?0.17; LC50 for DE = 0.36 mg\/g; CI 0.25?0.77). The laboratory bioassays resultsshowed that ants were not repelled by NSA. The average repellence percentage observed in the Petri dish bioassaywas 0.66 ± 3.1. No repellence was observed in field tests either, given that ants collected oat flakes treated withNSA (12.7 ± 1.2 oat flakes) in similar amounts to control oats (13.9 ± 1.6 oat flakes) after 2 h. Scanning electronmicroscope pictures showed that NSA was more effective than DE in attaching to the cuticle of exposed insects.This study reports for the first time the toxicity of NSA on leaf-cutting ants and shows that it has greater efficacythan DE in killing A. lobicornis at all the concentrations tested. Thus, NSA shows potential to be used as a dustinsecticide that could be applied directly at the nest to induce mortality of worker ants. Further studies shouldaddress the effect of NSA on the symbiotic fungus, as well as its potential as carrier for other insecticides orfungicides.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242993,"idioma_id":4,"titulo":"Nanostructured alumina:  Biocidal properties and mechanism of action of a novel insecticide powder","resumen":"Pest control using synthetic chemical pesticides is facing economic and environmental challenges worldwide. In this context, nanomaterials, emerge as potential tools that need to be investigated. The aim of this study was to examine the insecticidal effect and mode of action of nanostructured alumina (NSA) on Sitophilus oryzae, an insect pest of stored products as an experimental model organism. Results demonstrated that the mechanism of insecticide action of NSA is based on physical phenomena rather than on biochemical mechanisms. Charged NSA particles attach to the insects cuticle due to triboelectric forces, sorbing its wax layer by surface area phenomena, resulting in insect dehydration. Moreover, intake of NSA particles was observed to be an additional mortality factor in exposed insects. Results show that NSA could provide an alternative to conventional synthetic organic insecticides and warrant further research on the development of enhanced NSA derived products.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242994,"idioma_id":4,"titulo":"Plant based compounds with potential as Push - Pull stimuli to manage behaviour of leaf cutting ants","resumen":"Leaf-cutting ants are a serious pest of young forestry plantations. Currently, the main control method is the use of broad-spectrum insecticides, which have a negative effect on non-target organisms and the environment. In this work, plant-based compounds were evaluated in laboratory assays with Acromyrmex ambiguus Emery (Hymenoptera: Formicidae) for their potential use as repellent and attractant stimuli to be used in a push-pull strategy. Farnesol, a sesquiterpene present in many essential oils, was tested as a repellent at doses of 10, 50, and 100 mg. Its distance of action was studied by comparing the repellent effect of farnesol in a situation in which ants had to touch the farnesol in order to reach the food source in comparison to when ants could reach the food source without getting into direct contact with it. Different parts of the orange fruit (pulp and peel) were evaluated and compared as attractants, given that citrus-based baits are among the most popular attractants used. Results from laboratory bioassays indicated that farnesol is repellent at doses of 50 mg and acts upon contact or at a very short distance. Furthermore, orange pulp was more attractive than the peel, and volatile compounds were highly responsible for the attraction. When both stimuli were tested simultaneously in a laboratory experiment, repellency of farnesol was enhanced in the presence of orange pulp odor. When tested in a field push-pull experiment, the results also showed a good repellent effect of farnesol as well as an attractant effect of the orange pulp. These results encourage long-term studies with these substances in a field setting and suggest that repellents can be enhanced by the use of attractants to manage leaf-cutting ants behavior.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242997,"idioma_id":4,"titulo":"Multi-resolution anisotropy studies of ultrahigh-energy cosmic rays detected at the Pierre         Auger Observatory","resumen":"We report a multi-resolution search for anisotropies in the arrival directions of cosmic rays detected at the Pierre Auger Observatory with local zenith angles up to 80º and energies in excess of 4 EeV (4 × 10^18 eV). This search is conducted by measuring the angular power spectrum and performing a needlet wavelet analysis in two independent energy ranges. Both analyses are complementary since the angular power spectrum achieves a better performance in identifying large-scale patterns while the needlet wavelet analysis, considering the parameters used in this work, presents a higher efficiency in detecting smaller-scale anisotropies, potentially providing directional information on any observed anisotropies. No deviation from isotropy is observed on any angular scale in the energy range between 4 and 8 EeV. Above 8 EeV, an indication for a dipole moment is captured; while no other deviation from isotropy is observed for moments beyond the dipole one. The corresponding p-values obtained after accounting for searches blindly performed at several angular scales, are 1.3 × 10^&#8722;5 in the case of the angular power spectrum, and 2.5 × 10^&#8722;3 in the case of the needlet analysis. While these results are consistent with previous reports making use of the same data set, they provide extensions of the previous works through the thorough scans of the angular scales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242998,"idioma_id":4,"titulo":"Combined fit of spectrum and composition data as measured by the Pierre Auger Observatory","resumen":"We present a combined fit of a simple astrophysical model of UHECR sources to both the energy spectrum and mass composition data measured by the Pierre Auger Observatory. The fit has been performed for energies above 5 &#267; 1018 eV, i.e. the region of the all-particle spectrum above the so-called 'ankle' feature. The astrophysical model we adopted consists of identical sources uniformly distributed in a comoving volume, where nuclei are accelerated through a rigidity-dependent mechanism. The fit results suggest sources characterized by relatively low maximum injection energies, hard spectra and heavy chemical composition. We also show that uncertainties about physical quantities relevant to UHECR propagation and shower development have a non-negligible impact on the fit results.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":242999,"idioma_id":4,"titulo":"Impact of atmospheric effects on the energy reconstruction of air showers observed by the surface detectors of the Pierre Auger Observatory","resumen":"Atmospheric conditions, such as the pressure (P), temperature (T) or air density (&#961;&#8733;P\/T), affect the development of extended air showers initiated by energetic cosmic rays. We study the impact of the atmospheric variations on the reconstruction of air showers with data from the arrays of surface detectors of the Pierre Auger Observatory, considering separately the one with detector spacings of 1500 m and the one with 750 m spacing. We observe modulations in the event rates that are due to the influence of the air density and pressure variations on the measured signals, from which the energy estimators are obtained. We show how the energy assignment can be corrected to account for such atmospheric effects.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243000,"idioma_id":4,"titulo":"Muon counting using silicon photomultipliers in the AMIGA detector of the Pierre Auger observatory","resumen":"AMIGA (Auger Muons and Infill for the Ground Array) is an upgrade of the Pierre Auger Observatory designed to extend its energy range of detection and to directly measure the muon content of the cosmic ray primary particle showers. The array will be formed by an infill of surface water-Cherenkov detectors associated with buried scintillation counters employed for muon counting. Each counter is composed of three scintillation modules, with a 10 m2 detection area per module. In this paper, a new generation of detectors, replacing the current multi-pixel photomultiplier tube (PMT) with silicon photo sensors (aka. SiPMs), is proposed. The selection of the new device and its front-end electronics is explained. A method to calibrate the counting system that ensures the performance of the detector is detailed. This method has the advantage of being able to be carried out in a remote place such as the one where the detectors are deployed. High efficiency results, i.e. 98% efficiency for the highest tested overvoltage, combined with a low probability of accidental counting (~2%), show a promising performance for this new system.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243001,"idioma_id":4,"titulo":"A Targeted Search for Point Sources of EeV Photons with the Pierre Auger Observatory","resumen":"Simultaneous measurements of air showers with the &#64258;uorescence and surface detectors of the Pierre Auger Observatory allow a sensitive search for EeV photon point sources. Several Galactic and extragalactic candidate objects are grouped in classes to reduce the statistical penalty of many trials from that of a blind search and are analyzed for a signi&#64257;cant excess above the background expectation. The presented search does not &#64257;nd any evidence for photon emission at candidate sources, and combined p-values for every class are reported. Particle and energy &#64258;ux upper limits are given for selected candidate sources. These limits signi&#64257;cantly constrain predictions of EeV proton emission models from non-transient Galactic and nearby extragalactic sources, as illustrated for the particular case of the Galactic center region.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243002,"idioma_id":4,"titulo":"Multi-resolution anisotropy studies of ultrahigh-energy cosmic rays detected at the Pierre         Auger Observatory","resumen":"We report a multi-resolution search for anisotropies in the arrival directions of cosmic rays detected at the Pierre Auger Observatory with local zenith angles up to 80° and energies in excess of 4 EeV (4 × 1018 eV). This search is conducted by measuring the angular power spectrum and performing a needlet wavelet analysis in two independent energy ranges. Both analyses are complementary since the angular power spectrum achieves a better performance in identifying large-scale patterns while the needlet wavelet analysis, considering the parameters used in this work, presents a higher efficiency in detecting smaller-scale anisotropies, potentially providing directional information on any observed anisotropies. No deviation from isotropy is observed on any angular scale in the energy range between 4 and 8 EeV. Above 8 EeV, an indication for a dipole moment is captured; while no other deviation from isotropy is observed for moments beyond the dipole one. The corresponding p-values obtained after accounting for searches blindly performed at several angular scales, are 1.3 × 10-5 in the case of the angular power spectrum, and 2.5 × 10-3 in the case of the needlet analysis. While these results are consistent with previous reports making use of the same data set, they provide extensions of the previous works through the thorough scans of the angular scales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243003,"idioma_id":4,"titulo":"Combined fit of spectrum and composition data as measured by the Pierre Auger Observatory","resumen":"We present a combined fit of a simple astrophysical model of UHECR sources to both the energy spectrum and mass composition data measured by the Pierre Auger Observatory. The fit has been performed for energies above 5 &#267; 1018 eV, i.e. the region of the all-particle spectrum above the so-called 'ankle' feature. The astrophysical model we adopted consists of identical sources uniformly distributed in a comoving volume, where nuclei are accelerated through a rigidity-dependent mechanism. The fit results suggest sources characterized by relatively low maximum injection energies, hard spectra and heavy chemical composition. We also show that uncertainties about physical quantities relevant to UHECR propagation and shower development have a non-negligible impact on the fit results.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243004,"idioma_id":4,"titulo":"Impact of atmospheric effects on the energy reconstruction of air showers observed by the surface detectors of the Pierre Auger Observatory","resumen":"Atmospheric conditions, such as the pressure (P), temperature (T) or air density (&#961;&nbsp;&#8733;&nbsp;P\/T), affect the development of extended air showers initiated by energetic cosmic rays.  We study the impact of the atmospheric variations on the reconstruction of air showers with data from the arrays of surface detectors of the Pierre Auger Observatory, considering separately the one with detector spacings of 1500 m and the one with 750 m spacing.  We observe modulations in the event rates that are due to the influence of the air density and pressure variations on the measured signals, from which the energy estimators are obtained. We show how the energy assignment can be corrected to account for such atmospheric effects.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243005,"idioma_id":4,"titulo":"Muon counting using silicon photomultipliers in the AMIGA detector of the Pierre Auger observatory","resumen":"AMIGA (Auger Muons and Infill for the Ground Array) is an upgrade of the Pierre Auger Observatory designed to extend its energy range of detection and to directly measure the muon content of the cosmic ray primary particle showers. The array will be formed by an infill of surface water-Cherenkov detectors associated with buried scintillation counters employed for muon counting. Each counter is composed of three scintillation modules, with a 10 m 2 detection area per module. In this paper, a new generation of detectors, replacing the current multi-pixel photomultiplier tube (PMT) with silicon photo sensors (aka. SiPMs), is proposed. The selection of the new device and its front-end electronics is explained. A method to calibrate the counting system that ensures the performance of the detector is detailed. This method has the advantage of being able to be carried out in a remote place such as the one where the detectors are deployed. High efficiency results, i.e. 98% efficiency for the highest tested overvoltage, combined with a low probability of accidental counting (~2%), show a promising performance for this new system.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243006,"idioma_id":4,"titulo":"A Targeted Search for Point Sources of EeV Photons with the Pierre Auger Observatory","resumen":"Simultaneous measurements of air showers with the fluorescence and surface detectors of the Pierre Auger Observatory allow a sensitive search for EeV photon point sources. Several Galactic and extragalactic candidate objects are grouped in classes to reduce the statistical penalty of many trials from that of a blind search and are analyzed for a significant excess above the background expectation. The presented search does not find any evidence for photon emission at candidate sources, and combined p-values for every class are reported. Particle and energy flux upper limits are given for selected candidate sources. These limits significantly constrain predictions of EeV proton emission models from non-transient Galactic and nearby extragalactic sources, as illustrated for the particular case of the Galactic center region.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243008,"idioma_id":5,"titulo":"PUEBLOS INDÍGENAS EN TIEMPO DE CAMBIO: NUEVAS (Y NO TAN NUEVAS) FRONTERAS","resumen":"Mucho se viene hablando de los pueblos indígenas por estas horas en Argentina a partir de una presencia mediática inusitada, en estrecha relación con un hecho que viene conmocionando al país: la desaparición forzada del militante Santiago Maldonado, luego del allanamiento por parte de la Gendarmería Nacional a la comunidad ?Pu Lof en Resistencia? de Cushamen, provincia de Chubut. Esta realidad nos convoca a formular algunas aclaraciones como profesionales con una trayectoria de años en el trabajo con pueblos indígenas.Deseamos poner sobre el tapete qué intereses subyacen tras esta campaña mediática, y los riesgos que conlleva para el conjunto de comunidades del país.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243009,"idioma_id":4,"titulo":"A new interpretation and palaeoecological significance of the fossil bee cell cluster Rosellichnus patagonicus (Celliformidae)","resumen":"The trace fossil Rosellichnus patagonicus preserved in palaeosols is a cluster of vertical bee cells with smooth inner surface and discrete walls. R. patagonicus was originally described from two fragmentary specimens which limited a morphological analysis, the correct interpretation of the producer and palaeoecological inferences. Abundant specimens of R. patagonicus recently collected from several Cenozoic localities of Patagonia, principally from the La Pava Formation at Paso del Sapo, have allowed the recognition of a complete set of morphological characters, among which the curved neck of some cells is particularly significant. Isolated cells in the same outcrops show similar curved necks. Such cells are constructed only by diphaglossinae bees, to which clusters and isolated cells may be attributed. These trace fossils are particularly comparable with extant cells and clusters of Cadeguala albopilosa (Diphaglossinae) which at present nests in forest clearings with grass cover. Accordingly, the andic mollisols from the Miocene La Pava Formation, where R. patagonicus is abundant, formed in warm-temperate, sub-humid and seasonal conditions, under grass-dominated vegetation with subordinate tree coverage.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243010,"idioma_id":4,"titulo":"Cricket oviposition trace fossils in palaeosols and their stratigraphic significance: The South American Palaeosol Ichnofossil Ages (SAPIAs)","resumen":"The first insect trace fossil in palaeosols attributed to the oviposition of crickets is represented by openings composed of two to four, but usually three, perforations with a tripartite pattern. This pattern is compatible with the cross section of the distal ovipositor of some crickets. The new ichnotaxon Bellosichnus tripartitus igen. isp. nov. represents a novel architectural design among insect trace fossils in palaeosols. It may reflect true ovipositions or the behavior of testing soil with the ovipositors performed by crickets. In accordance, this trace fossil would be indicative of the surface soil horizon. Bellosichnus tripartitus is abundant in the lower section of the Sarmiento Formation (middle Eocene Casamayoran Age) and it is almost absent before and after this interval in other terrestrial successions of Patagonia. It is a trace fossil with high stratigraphic significance. Bellosichnus tripartitus and other insect trace fossils in palaeosols with similar stratigraphic significance comprise several assemblages, which are representative of different ages along the Cenozoic of southern South America. Such assemblages are typical of particular ages that are named herein South American Palaeosol Ichnofossil Ages (SAPIAs). The SAPIAs run in parallel with the South American Land Mammal Ages (SALMAs). The SAPIAs would be useful to make predictions not only on ages, but also on possible mammal faunas and palaeoenvironments in understudied palaeontological localities.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243011,"idioma_id":5,"titulo":"FUENTES DEL DIPu (sobre fuentes clásicas y contemporáneas del DIPu)","resumen":"Lamás antigua y simple respuesta a la pregunta sobre las fuentes del derechointernacional público (DIPu de aquí en más) refiere dos principales: (i) lostratados, y (ii) el DI consuetudinario. Ambas son creadas por los Estados, deforma tal que los Estados se encuentran obligados en la medida de suconsentimiento pasado y presente. Esta respuesta técnica revela muy poco sobrecómo se generan, se invocan y aplican estas fuentes. Esteartículo parte del análisis del art. 38 del Estatuto de la CIJ, para evaluar apartir de su contenido, las fuentes citadas y sobre todo aquellas que han sidoallí omitidas. Respecto de éstas, en algunas el olvido fue intencional, al noser consideradas suficientemente ?tradicionales? al momento de la redacción delartículo, en los inicios del siglo XX. En otros casos, actos que hoy revistenla calidad de fuentes, directamente no existían o su desarrollo sólo seevidenciaba en forma embrionaria hace ya un siglo. El presente impone revisaresta cuestión, considerando que uno de los grandes paradigmas del siglo XX ?los derechos humanos- no había surgido a la consideración del DI a principiosdel siglo XX, por lo cual, varias de las hoy consideradas fuentes quemejor&nbsp; defienden su status dentro delsistema de normas internacionales, son subestimadas o relegadas al momento deinterpretar el DI por parte de ciertos tribunales internacionales. Por esto,las analizaremos bajo el título genérico de ?fuentes contemporáneas? del DI.Ensuma, en el desarrollo del presente trabajo, (i) re-interpretaremos las fuentestradicionales del DI que nacen a partir de la voluntad y consentimientoexclusivo de los Estados en el contexto actual de la necesidad de respeto delparadigma de los derechos humanos; y (ii) sopesaremos el valor de otros hechosgeneradores de normas internacionales y facilitadores del desarrollo progresivodel DI que tratamos bajo el título de fuentes contemporáneas del DI.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243012,"idioma_id":5,"titulo":"LA ELUCIDACION DE LA COSTUMBRE INTERNACIONAL EN SITUACIONES QUE ATENTAN CONTRA LOS DERECHOS HUMANOS.","resumen":"La más antigua y simple respuesta a la pregunta sobre las fuentes del derechointernacional refiere dos principales: (i) los tratados, y (ii) el DI consuetudinario.Ambas son creadas por los Estados, de forma tal que los Estados se encuentranobligados en la medida de su consentimiento pasado y presente. Esta respuestatécnica revela muy poco sobre cómo se generan, se invocan y aplican esas fuentes.Este artículo se plantea como objetivo analizar la costumbre como fuente del DI,focalizando en la manera en que es afirmada como medio de prueba en un conflictointernacional y en las decisiones de la Corte Internacional de Justicia y otrostribunales internacionales en que la misma es determinada. Entendemos queademás de las conductas estatales y la convicción de su obligatoriedad (opinioiuris), otros elementos deben ser considerados a fin de establecer o negar laexistencia de una costumbre internacional, especialmente cuando la misma esinvocada como fundamento de los derechos de la persona humana frente alEstado. Se reitera aquí el conflicto latente entre dos tradiciones: (i) la que prioriza la soberanía estatal y (ii) aquella que privilegia los derechos humanos. La primera requerirá la aceptación plena de los Estados, expresada a través de sus conductas consideradas vinculantes. Aquí el método a utilizar será inductivo. La segunda elaborará sobre las tendencias legislativas modernas, el soft law y la opinio iuris referidas a la obligatoriedad del respeto de un mínimo de derechos como límite a la voluntad soberana estatal. En este caso, el método deductivo será la herramienta a utilizar. Si solo se repara en los elementos tradicionales de la costumbre internacional establecidos hace siglos por el DI, llegaremos a decisiones judiciales que consolidan el sistema de Estados soberanos, sin importar si las mismas se alejan del ideal de justicia y protección de los derechos humanos, como, por ejemplo, lo refleja las sentencias de la CIJ en Orden de Arresto o en Inmunidades Jurisdiccionales del Estado. Para que eso no suceda, intentaremos demostrar que otros medios reveladores de la práctica general y obligatoria han de ser utilizados.Estos tienen su base en la doctrina de los derechos humanos, complementan el accionar estatal y le fijan límites.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243014,"idioma_id":4,"titulo":"Influence of Cryogenic Treatments on the Fracture Toughness of AISI 420 Martensitic Stainless Steel","resumen":"Cryogenic treatments have been employed over the past three decades for both tool and high-alloy steels to improve their wearresistance, mainly through the transformation of retained austenite and the precipitation of fine carbides. However, as theenhancement of one material property is often at the expense of another, it is interesting to evaluate the effect of this type oftreatments on the fracture toughness. The objective of the present work was to determine the plane-strain fracture toughness of acryogenically treated low-carbon AISI 420 martensitic stainless steel by means of standardized fracture tests, performed inaccordance with the ASTM E399 and ASTM E1820 standards. In this study, it was experimentally demonstrated thatcryogenically treated specimens showed a simultaneous increase in the KIC and hardness of 30 % and 5 %, respectively,compared to conventionally treated specimens.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243015,"idioma_id":4,"titulo":"Nanotribological behavior of deep cryogenically treated martensitic stainless steel","resumen":"Cryogenic treatments are increasingly used to improve the wear resistance of various steel alloys by means of transformation ofretained austenite, deformation of virgin martensite and carbide refinement. In this work the nanotribological behavior and mechanical properties at the nano-scale of cryogenically and conventionally treated AISI 420 martensitic stainless steel were evaluated.Conventionally treated specimens were subjected to quenching and annealing, while the deep cryogenically treated samples were quenched, soaked in liquid nitrogen for 2 h and annealed. The elastic?plastic parameters of the materials were assessed by nanoindentation tests under displacement control, while the friction behavior and wear rate were evaluated by a nanoscratch testing methodology that it is used for the first time in steels. It was found that cryogenic treatments increased both hardness and elastic limit ofa low-carbon martensitic stainless steel, while its tribological performance was enhanced marginally.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243016,"idioma_id":4,"titulo":"Influence of Cryogenic Treatments on the Wear Behavior of AISI 420 Martensitic Stainless Steel","resumen":"Cryogenic treatments have been employed over the last three decades in both tool and high-alloy steels to improve wear resistance, mainly through the transformation of retained austenite and the precipitation of fine carbides. The application of these treatments to low-alloy steels and even to non-ferrous materials is becoming the subject of several investigations, due to their potentiality to reduce wear.The objective of the present work is to characterize the wear behavior of a cryogenically treated low-carbon AISI 420 martensitic stainless steel, by means of pin-on-disk tribological tests. Wear tests were performed according to ASTM G99 standard, under a range of applied normal loads and in two different environments, namely a vaseline bath and an argon atmosphere. Wear tracks were analyzed by optical microscopy and scanning electron microscopy (SEM) to evaluate wear volume, track geometry, surface features and the tribolayers generated after testing.In this study, it has been experimentally demonstrated that cryogenically treated specimens showed a wear resistance improvement ranging from 35 to 90% compared to conventionally treated ones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243017,"idioma_id":5,"titulo":"EXPERIENCIAS DE ECONOMIA SOCIAL Y SOLIDARIA EN NECOCHEA Y QUEQUEN. Avances de lo local a lo regional","resumen":"En el presente trabajo,se difunden datos y resultados generados a partir de un proyecto de extensión desarrolladodesde la UNICEN (Universidad Nacional del Centro de la provincia de BuenosAires) en y con las comunidades; &nbsp;se describenalgunas experiencias cooperativas, asociativas y productivas gestadas en clavede &nbsp;Economía Social y Solidaria (ESS) quevienen desarrollándose en&nbsp; la región delcentro de la provincia de Buenos Aires (Argentina), específicamente en la zonacostera de Necochea y Quequén.&nbsp; Elproyecto macro que encuadra estas experiencias fue desarrollado entre 2015-2016en toda la región sudoeste y se orientó a indagar&nbsp; los marcos normativos y estrategias degestión, visibilidad y comercialización de las mismas. Específicamente, en estainstancia, se presenta&nbsp; parte delrelevamiento y diagnóstico efectuado sobre la economía 'realmenteexistente' (Coraggio 1998) en el cual se relevaron: actoresintervinientes, prácticas&nbsp; implementadas,balances y dificultades de los procesos de trabajo. Complementando eldiagnóstico, propositivamente, el&nbsp;proyecto&nbsp; busca&nbsp; potenciar, ampliar y expandir lasexperiencias analizadas y dar cuenta de las tensiones que supone la lógica deconstrucción de la Economía Social y Solidaria (ESS) atendiendo a&nbsp; las&nbsp;condiciones&nbsp; materiales&nbsp; concretas&nbsp;de&nbsp; los diversos&nbsp; territorios&nbsp;de la región y a los sentidos que para los actores adquieren estasexperiencias.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243022,"idioma_id":5,"titulo":"'Una congregación de fe'","resumen":"El artículo es un ensayo etnográfico que busca identificar las particularidades y las prácticas culturales de un grupo evangelista de la localidad de hudson, provincia de Buenos Aires. A través de entrevistas y la observación participante, se aborda una descripción que apunta a tener un punto de partida en la singularidad de este grupo religioso.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243023,"idioma_id":4,"titulo":"Biochemical and microbiological changes throughout the ripening of Argentinean fresh goat?s milk cheeses made with native cultures","resumen":"Two different cultures with native lactic acid bacteria (LAB) were designed, S (starter culture consisting of Lactobacillus (L.) rhamnosus UNSE308, L. delbrueckii subsp. bulgaricus UNSE309, Streptococcus (S). thermophilus UNSE314, S. thermophilus UNSE321) and A (starter culture S plus adjunct culture consisting of L. plantarum UNSE316, L. plantarum UNSE317, Pediococcus (P). pentosaceus UNSE22, P. pentosaceus UNSE253). Cultures S, A and C (lyophilized commercial culture of Streptococcus thermophillus) were used to manufacture fresh goat cheeses (CS, CA and CC) from pasteurized milk. The impact of these cultures on the microbiological, biochemical and physicochemical parameters were evaluated during ripening (30 days). Results evidenced that CC, CA and CS did not show significant differences in protein and fat content, NaCl, acidity, fat acidity and aw, at the same time of ripening. All experimental cheeses underwent moderate lipolysis since moderate levels of free fatty acids (FFA) at the end of ripening were detected (~1.5 g kg-1)  and made an important contribution to characteristic flavour and aroma. In all cases, a slight proteolysis was detected; CC showed the lowest levels during ripening. Values of NaCl (1.27%) were in accordance with those reported in most cheeses. During ripening, mesophilic LAB counts in MRS agar increased nearly 1 log cycle, total coliforms per gram at 30ºC showed counts below the maximum allowed by Argentinean legislation. Overall impression of CS and CA was qualified as good compared to CC that was scored as regular. The fresh goat cheeses made with native cultures presented suitable typical flavour and satisfying overall sensorial characteristics.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243024,"idioma_id":4,"titulo":"Nutraceutical emulsion containing valproic acid (NE-VPA): a drug delivery system for reversion of seizures in zebrafish larvae epilepsy model","resumen":"Valproic acid (VPA) is an antiepileptic drug, which is currently used in neurodegenerative diseases. However, a high dose is required to obtain a therapeutic effect. Long-chain polyunsaturated fatty acids (PUFAs), such as omega 3 and omega 6, are efficient complements in treatments for neurological diseases. Previous studies have reported that a dietary supplement containing PUFAs together with the administration of antiepileptic drugs significantly reduces the frequency of seizures. Based on this, the main goal of this work was to obtain a complex based on VPA encapsulation in an oil\/water (o\/w) nutraceutical emulsion (NE) enriched with PUFAs for oral administration. Besides, encapsulation of VPA might reduce its dose and increase its therapeutic effect. In order to study its effect, we used a zebrafish larvae model of induced epileptiform behavior with the proconvulsant drug pentylenetetrazol (PTZ). Results have shown that when 100 &#956;M VPA and fatty acids were combined in the NE (NE-VPA), the epileptiform behavior of PTZ-treated zebrafish larvae decreased significantly. Additionally, morphological changes, hepatotoxicity, lethality and heart rate were studied. Despite the fact that a high dose of VPA exerted a cardiotoxic effect, this was no longer detected after addition of this drug in the NE. This treatment exerted a significant antiepileptic effect and did not result in highly toxic or lethal effects. In order to develop an improved pharmaceutical treatment, and considering that all the components used are FDA approved for consumption, the NE-VPA selected might be easily incorporated into clinical trials.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243025,"idioma_id":4,"titulo":"Albumin nanocarriers, &gamma; - irradiated crosslinked, combined with therapeutic drugs for cancer therapy","resumen":"Albumin polymeric Nanoparticles (NPs) have opened a great expectancy as for controlled drug delivery due to their therapeutic potency. Concomitantly biodegradable NPs technologies with target linked structures to pave the way of personalised medicine are becoming increasingly important in sight of a therapeutically effective research technology. This is particularly attractive for nanoparticle-based cancer delivery systems, based on the known limitations and efforts to overcome.  This new group of gamma irradiated-NPs inherited both the protein delivery properties and robustness of polymer forming structures, and gamma irradiation techniques that leave clean, innocuous and biodegradable NPs. These protein NPs made of serum albumin are referred to SA NPs that possesses several characteristics making them especially attractive to be considered as a drug delivery system. This reviews focused on methodologies actually being used in the synthesis and characterisation of albumin NPs and different author?s opinions on strategic ways to treat cancerous cell-lines with NPs. Utterly, challenges being overthrown by researchers are brought up to anneal an effective, all in one targeted albumin NPs to passed through in vitro and preclinical trials. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243026,"idioma_id":4,"titulo":"Nanotoxicological and Teratogenic Effects: A Linkage Between  Dendrimer Surface Charge and Zebrafish Developmental Stages","resumen":"This&nbsp; article&nbsp; reports&nbsp; novel&nbsp; results&nbsp; about&nbsp; nanotoxicological&nbsp; and&nbsp; teratogenic&nbsp; effects&nbsp; of&nbsp; the PAMAM dendrimers DG4 and DG4.5 in zebrafish&nbsp; (Danio rerio). Zebrafish embryos and larvae were used as a rapid, high-throughput, cost-effective whole-animal model. The objective was to provide&nbsp; a&nbsp; more&nbsp; comprehensive&nbsp; and&nbsp; predictive&nbsp; developmental&nbsp; toxicity&nbsp; screening&nbsp; of&nbsp; DG4&nbsp; and DG4.5 and test the influence of&nbsp; their surface charge. Nanotoxicological and teratogenic effects were&nbsp; assessed&nbsp; at&nbsp; developmental,&nbsp; morphological,&nbsp; cardiac,&nbsp; neurological&nbsp; and&nbsp; hepatic&nbsp; level.&nbsp; The effect of surface charge was determined in both larvae and embryos. DG4 with positive surface charge&nbsp; was&nbsp; more&nbsp; toxic&nbsp; than&nbsp; DG4.5&nbsp; with&nbsp; negative&nbsp; surface&nbsp; charge.&nbsp; DG4&nbsp; and&nbsp; DG4.5&nbsp; induced teratogenic effects in larvae, whereas DG4 also induced lethal effects in&nbsp; both zebrafish embryos and larvae. However, larvae were less sensitive than embryos to the lethal effec ts of DG4. The platform of assays proposed and data obtained may contribute to the characterization of hazards and differential&nbsp; effects of these nanoparticles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243027,"idioma_id":4,"titulo":"Relation between biophysical properties of nanostructures and their toxicity on zebrafish","resumen":"In recent years, the use of commercial nanoparticles in different industry and health fields has increased exponentially. However, the uncontrolled application of nanoparticles might present a potential risk to the environment and health. Toxicity of these nanoparticles is usually evaluated by a fast screening assay in zebrafish (Danio rerio). The use of this vertebrate animal model has grown due to its small size, great adaptability, high fertilization rate and fast external development of transparent embryos. In this review, we describe the toxicity of different micro- and nanoparticles (carbon nanotubes, dendrimers, emulsions, liposomes, metal nanoparticles, and solid lipid nanoparticles) associated to their biophysical properties using this model. The main biophysical properties studied are size, charge and surface potential due to their impact on the environment and health effect. The review also discusses the correlation of the effects of the different nanoparticles on zebrafish. Special focus is made on morphological abnormalities, altered development and abnormal behavior. The last part of the review debates on changes that should be made in future directions in order to improve the use of the zebrafish model to assess nanotoxicity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243028,"idioma_id":4,"titulo":"Skin penetration and UV-damage prevention by nanoberries","resumen":"SummaryBackgroundEthanolic extract from blueberry (Vaccinium myrtillus) is rich in anthocyanins and thus exhibits antioxidant activity. On the other hand, ultradeformable liposomes are capable of penetrating to the impermeable barrier of skin. Nanoberries are ultradeformable liposomes carrying blueberry extract.ObjectivesIn this study, their capacity to penetrate the stratum corneum and photodamage prevention were tested, with the aim of developing a topical formulation for skin protection from environmental damage.MethodsNanoberries were prepared by lipid film resuspension with ethanolic extract from blueberry, followed by sonication and incorporation to a gel. Size, zeta potential, deformability, rheology, and viscoelasticity were determined. Toxicity was assessed in vivo in zebrafish model, while in vitro cytotoxicity assay was performed on HaCaT and HEK-293T cell lines. Skin penetration was evaluated with the Saarbrücken penetration model followed by tape stripping, cryosection, or optical sectioning. UV-damage protection and photoprotection were determined by ad hoc methods with UVA, UVB, and UVC radiation on HaCaT cells. Wound assay was performed on HaCaT cells.ResultsNanoberries of about 100 nm, with differential elastic properties, did penetrate the stratum corneum, with low toxicity. When HaCaT cells were exposed to UV radiation in the presence of nanoberries, their viability was maintained.ConclusionsNanoberries could be effective to protect the skin from sun photodamage.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243029,"idioma_id":4,"titulo":"Diacetylenic lipids in the design of stable lipopolymers able to complex and protect plasmid DNA","resumen":"Different viral and non-viral vectors have been designed to allow the delivery of nucleic acids in gene therapy. In general, non-viral vectors have been associated with increased safety for in vivo use; however, issues regarding their efficacy, toxicity and stability continue to drive further research. Thus, the aim of this study was to evaluate the potential use of the polymerizable diacetylenic lipid 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine (DC8,9PC) as a strategy to formulate stable cationic lipopolymers in the delivery and protection of plasmid DNA. Cationic lipopolymers were prepared following two different methodologies by using DC8,9PC, 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), and the cationic lipids (CL) 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP), stearylamine (SA), and myristoylcholine chloride (MCL), in a molar ratio of 1:1:0.2 (DMPC:DC8,9PC:CL). The copolymerization methodology allowed obtaining cationic lipopolymers which were smaller in size than those obtained by the cationic addition methodology although both techniques presented high size stability over a 166-day incubation period at 4&#730;C. Cationic lipopolymers containing DOTAP or MCL were more efficient in complexing DNA than those containing SA. Moreover, lipopolymers containing DOTAP were found to form highly stable complexes with DNA, able to resist serum DNAses degradation. Furthermore, neither of the cationic lipopolymers (with or without DNA) induced red blood cell hemolysis, although metabolic activity determined on the L-929 and Vero cell lines was found to be dependent on the cell line, the formulation and the presence of DNA. The high stability and DNA protection capacity as well as the reduced toxicity determined for the cationic lipopolymer containing DOTAP highlight the potential advantage of using lipopolymers when designing novel nonviral carrier systems for use in in vivo gene therapy. Thus, this work represents the first steps toward developing a cationic lipopolymer-based gene delivery system using polymerizable and cationic lipids.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243030,"idioma_id":5,"titulo":"Caracterización microbiológica de polen comercial. Reporte Preliminar","resumen":"La producción de polen ha ido incrementándose como respuesta a la demandade los consumidores, presentándose como una alternativa de diversificación parala producción apícola. Si bien el consumo de polen se promueve por suspropiedades nutricionales y terapéuticas no existe en Argentina un protocolopara la obtención de polen apicola de calidad. El presente trabajo fue realizadocon el objetivo de estudiar la calidad microbiológica de pólenes comercializadosy aportar información para conocer si la conservación y presentación del polencomercial pueden ser variables críticas de control. Se determinó la humedadmediante secado en estufa expresando los resultados en porcentaje. Los análisismicrobiológicos realizados fueron recuentos de mohos y levaduras, aerobiostotales y coliformes totales, investigación de Salmonella spp y clostridios sulfitosreductores.Los valores de humedad variaron entre 12.9 y 22%. Las muestrascomercializadas a granel tenían significativamente mayor valor de humedadcuando estaban conservadas a temperatura ambiente que las muestrasrefrigeradas (F=6.54; P=0.02), mientras que la humedad del polen fraccionadono fue significativamente diferente entre los dos estados de conservación.Los resultados evidencian una alta diversidad microbiológica, con valoresmenores a 102 UFC\/g de mohos y levaduras para el 28% de las muestras,mientras que para aerobios totales los valores oscilaron entre 103 y 8.5 X 103UFC\/g. El 0.2% de las muestras presentaron Escherichia coli, detectándose en el22% de las muestras presencia de clostridios sulfito reductores.Los elevados valores de humedad ponen en evidencia que los métodos,procedimientos de secado y temperatura deben estandarizarse.Son necesarios más estudios que evalúen la calidad en todo el proceso desde larecolección hasta la comercialización a fin de establecer los puntos críticos decontrol para evitar el deterioro del producto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243031,"idioma_id":4,"titulo":"Notch system is differentially expressed and activated in pituitary adenomas of distinct histotype, tumor cell lines and normal pituitaries","resumen":"Pituitary adenomas are among the most frequent intracranial neoplasms andtreatment depends on tumor subtype and clinical features. Unfortunately, nonresponder cases occur, then new molecular targets are needed.Notch system component expression and activation data are scarce in pituitarytumorigenesis, we therefore aimed to characterize Notch system in pituitary tumors of different histotype. In human pituitary adenomas we showed NOTCH1-4 receptors, JAGGED1 ligand and HES1 target gene expression with positive correlations between NOTCH1,2,4 and HES1, and NOTCH3 and JAGGED1 denoting Notch system activation in a subset of tumors. Importantly, NOTCH3 positive cells were higher in corticotropinomas and somatotropinomas compared to non functioning adenomas. In accordance, Notch activation was evidenced in AtT20 tumor corticotropes, with higher levels of NOTCH1-3 active domains, Jagged1 and Hes1 compared to normal pituitary.In the prolactinoma cell lines GH3 and MMQ, in vivo GH3 tumors and normalglands, Notch system activation was lower than in corticotropes. In MMQ cells only the NOTCH2 active domain was increased, whereas NOTCH1 active domain was higher in GH3 tumors. High levels of Jagged1 and Dll1 were found solely in GH3 cells, and Hes1, Hey1 and Hey2 were expressed in a model dependent pattern.Prolactinomas harbored by lacDrd2KO mice expressed high levels of NOTCH1active domain and reduced Hes1.We show a differential expression of Notch system components in tumoral andnormal pituitaries and specific Notch system involvement depending on adenomahistotype, with higher activation in corticotropinomas. These data suggest thattargeting Notch pathway may benefit non responder pituitary adenomas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243032,"idioma_id":5,"titulo":"Toxicidad in vitro de extractos acuosos e hidroalcohólico de Prosopis ruscifolia","resumen":"Prosopis ruscifolia Griseb, conocido popularmente como ?vinal? es un arbusto o árbol leguminoso de la familia Fabaceae que está presente en América del Sur incluyendo Paraguay y la Argentina. En la Argentina abarca aproximadamente 2 millones de hectáreas incluyendo la región del Chaco. La propiedad medicinal que se le atribuye principalmente es la actividad antimicrobiana de sus hojas debido a la presencia de un alcaloide (vinalina). Esto hace que sea utilizada por los nativos para tratar afecciones oculares por instilación de una infusión. Además, se la utiliza, especialmente en Paraguay, en la medicina popular para disminuir la glucosa en sangre. Sin embargo, es necesario evaluar la toxicidad de esta planta medicinal ampliamente usada. El objetivo general de este trabajo fue determinar la toxicidad in vitro de extractos acuosos e hidroalcohólico de las hojas de Prosopis ruscifolia recolectado en la provincia del Chaco. Los objetivos específicos del trabajo fueron la recolección del material vegetal, la preparación de los extractos y la determinación de la toxicidad in vitro de los mismos. La metodología utilizada fue: i) recolección del material vegetal (hojas), acondicionamiento, secado y molienda; ii) preparación de los extractos acuosos mediante el contacto con agua destilada (100 °C) durante 10 minutos (infusión) o la ebullición con agua destilada (100 °C) durante 10 minutos (decocción); iii) preparación del extracto hidroalcohólico mediante maceración de las hojas con etanol 96° durante 2 horas (65 °C); y iv) determinación de la toxicidad in vitro mediante el ensayo de Artemia salina utilizando concentraciones de 100 a 1.250 µg\/ml de cada extracto para determinar la concentración letal media (CL50) luego de 24 horas. Los resultados del ensayo evidenciaron que los tres extractos presentaban toxicidad aguda in vitro ya que los valores de CL50 fueron todos menores a 1.000 µg\/ml. Los valores de CL50 obtenidos fueron 643,7; 766,9 y 971,9 µg\/ml para infusión, decocción y extracto hidroalcohólico, respectivamente. En conclusión, Prosopis ruscifolia recolectado en el Chaco, a pesar de ser utilizado por la población en forma de infusión y decocción de sus hojas, posee toxicidad aguda in vitro, aunque estos ensayos deben ser ampliados y los resultados confirmados por métodos más complejos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243033,"idioma_id":4,"titulo":"Cationic antimicrobial peptides inactivate Shiga toxin-encoded bacteriophages","resumen":"Shiga toxin (Stx) is the principal virulence factor during Shiga toxin-producing Escherichia coli (STEC) infections.&nbsp;We have previously reported the inactivation of bacteriophage encoding Stx after chitosan treatment, a linear polysaccharide polymer with cationic properties.&nbsp; On the other hand,Cationic antimicrobial peptides (cAMPs) are short lineal aminoacidic sequences that share some common motifs, besides their highly positively net charge, which display&nbsp;bactericidal or bacteriostatic activity against a wide range of bacterial species, depending on the cAMP. They are promising novel antibiotics since they have shown bactericidal effects against multiresistant bacteria. To evaluate whether cationic properties are responsible for bacteriophage&nbsp;inactivation, we tested seven cationic peptides with proven antimicrobial activity as anti-bacteriophage agents, and one random sequence cationic peptide with no antimicrobial activity as a control. We observed bacteriophage inactivation after incubation with five cAMPs, but no inactivating activity was observed with the random sequence cationic peptide or with the non alpha helical cAMP Omiganan. Finally, to confirm peptide-bacteriophage interaction, Zeta potential was analyzed by following changes on bacteriophage surface charges after peptide incubation. Overall our data suggest that: 1. Direct interaction of peptides with phage is a necessary step for bacteriophage inactivation, 2. the charge of the bacteriophage is relevant but not enough for infection, and 3. inactivation by cationic peptides could be sequence specific. These peptides could be considered a new family of molecules potentially useful to avoid host bacterial infection,&nbsp;decreasing bacteriophage replication and Stx expression.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243036,"idioma_id":5,"titulo":"Farmacovigilancia en Medicina Herbaria","resumen":"La Farmacovigilancia es esencial para el desarrollo de información confiable sobre la seguridad de las hierbas medicinales utilizadas por la población. El objetivo del trabajo, fue analizar las notificaciones de Comunicación de Eventos Adversos por uso de Medicamentos Fitoterápicos, Productos Vegetales y\/o Preparados de Drogas Vegetales, recibidas como Efector Periférico Chaco de la Administración Nacional de Medicamentos, Alimentos y Tecnología Médica (ANMAT), durante enero 2010 a julio 2017. Se realizó un análisis retrospectivo de los reportes recibidos de farmacias y centros de salud utilizándose para su clasificación la guía Anatómica, Terapéutica, Química (ATC, de sus siglas en inglés) de hierbas. La causalidad se evaluó mediante el algoritmo de Naranjo y col. y la gravedad se describió en tres categorías: leve, moderada y grave. Los efectos adversos y\/o tóxicos se compararon con datos bibliográficos. De un total de 146 notificaciones, 81% implicó el uso de un producto vegetal único, 15% la mezcla de dos o más y 4% de medicamentos fitoterápicos. El 31% correspondió a niños y el resto involucró adultos, mientras que el sexo femenino 64%, prevaleció respecto al masculino. De acuerdo con la clasificación ATC de hierbas, 72% correspondió al grupo HA (tracto alimentario y metabolismo) como el más notificado, 13% al HN (sistema nervioso), 4% al HG (sistema genito urinario y hormonas sexuales), 3% al HC (sistema cardiovascular) y los demás en menor proporción. Con respecto a la gravedad, predominaron las reacciones adversas leves 51%, el resto se dividió en porcentajes similares entre moderada 26% y grave 23% y en cuanto a la causalidad, fueron clasificadas como probable 50%, posible 44% e improbable 6%. Las reacciones adversas estuvieron relacionadas principalmente a trastornos del sistema gastrointestinal 50%, sistema nervioso central y periférico 12%, general de todo el organismo 9% y los demás en menor proporción. Las hierbas medicinales más reportadas fueron Chenopodium ambrosioides L., Cassia angustifolia Vahl., Illicium verum Hook. f., Peumus boldus Molina y Matricaria recutita L. El seguimiento de las reacciones adversas es fundamental para generar información confiable sobre la seguridad de las hierbas medicinales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243038,"idioma_id":5,"titulo":"En torno a la educación religiosa en las escuelas públicas","resumen":"Con motivo de la consideración en la Corte Suprema de Justicia de la Nación de la causa ?CASTILLO, CARINA VIVIANA y OTROS C\/ PROVINCIA DE SALTA; MINISTERIO DE EDUCACION DE LA PROVINCIA DE SALTA S\/ AMPARO? EXPTE. N° 313.763\/10, en que se debate la educación religiosa en las escuelas públicas de Salta, compartimos algunas de las razones expresadas en nuestro escrito como ?Amigo del Tribunal? y que pueden contribuir a brindar respaldo a la sentencia emanada de la Suprema Corte de Salta que sostuvo la constitucionalidad de las normas salteñas referidas al tema.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243040,"idioma_id":5,"titulo":"El partido Vanguardia Comunista: elementos para avanzar en una caracterización del maoísmo argentino (1965-1971)","resumen":"Vanguardia Comunista fue la primera organización argentina en adoptar explícitamente el maoísmo como fundamento político ideológico. El presente trabajo busca indagar cómo fue y en función de qué adoptaron el maoísmo y cómo lo significaron y transformaron en el período abordado, en relación con su análisis y práctica en la sociedad argentina. A través del recorrido planteado y las fuentes partidarias trabajadas intentamos delinear los rasgos que fue adquiriendo el maoísmo argentino, del que Vanguardia Comunista fue uno de sus exponentes. Proponemos que, en un camino que no fue unívoco ni lineal, el maoísmo proveyó a esta organización de herramientas a través de las que pudieron repensar la realidad argentina, en diversos aspectos como la vía, el camino y el carácter de la revolución, y el significado del peronismo como corriente política.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243041,"idioma_id":5,"titulo":"Las disputas historiográficas en torno al cincuentenario del Golpe de Estado de 1964 en Brasil: un ejercicio para el abordaje del vínculo entre ciencia histórica y lucha de clases","resumen":"En 2014 se cumplieron cincuenta años del inicio del Golpe de Estado en Brasil yasistimos a un incremento de las publicaciones sobre la temática. Así como los historiadoreshan formulado explicaciones sobre el Golpe de Estado que derribó el gobierno de João Goulartel 1° de abril de 1964 y sobre los largos veintiún años que duró la dictadura, el conjunto de lasciencias humanas y sociales, los medios de comunicación, los partidos y organizacionespolíticas, la población que vivió el proceso y sus consecuencias también han reflexionado ytomado posición, aunque sea confusa y ambiguamente, sobre lo acontecido.En este trabajo nos proponemos analizar críticamente la obra académica producidasobre la temática por historiadores cariocas y paulistas de amplia difusión nacional en elperíodo 2010-20144: Daniel Aarão Reis, Jorge Ferreira y Angela de Castro Gomes, RodrigoPatto Sá Motta, Anderson da Silva Almeida, Marcos Napolitano, Samantha Viz Quadrat yDenisse Rollemberg. Partiendo de un diagnóstico de ?retraso? que presentarían los estudiossobre el Golpe, la Dictadura y los Derechos Humanos en Brasil, estos autores retomanconceptos de otras experiencias y las utilizan para analizar el caso brasilero. Identificamos ensus producciones la consolidación de una línea historiográfica que reclama el abordaje de unanueva y provocadora agenda de pesquisa. Es por ello que en este artículo intentaremossintetizar los puntos de partida, las ideas y conceptos centrales de la mencionada corriente,con el objetivo de problematizar el vínculo entre Historia y lucha de clases, concentrándonosen las consecuencias políticas y las limitaciones de tales interpretaciones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243042,"idioma_id":4,"titulo":"Dairy farm wastewater treatment using horizontal subsurface flow wetlands with Typha domingensis and different substrates","resumen":"The aim of this work was to evaluate the influence of different substrates in the performance of a horizontal flow constructed wetland employed in dairy farm wastewater treatment. Typha domingensis was chosen for this study due to its high productivity and efficiency in nutrient removal. Fifteen microcosm-scale reactors simulating horizontal flow constructed wetlands were disposed in a greenhouse in triplicate. Five substrates (river gravel, gravel, LECA, river gravel + zeolite and gravel + zeolite) were evaluated. Real effluent with previous treatment was used. Dairy farm effluents favoured T. domingensis growth, probably due to their high nutrient concentrations. The treatments with the different substrates studied were efficient in the treatment of the dairy farm effluent obtaining ammonium (NH+ 4) and total phosphorus (TP) removals between 88?99% and 86?99%, respectively. Removal efficiencies were significantly higher in treatments using LECA and combined substrate (gravel + zeolite). After treatment, the quality of the final effluent was significantly improved. Outlet effluent complied with regulations and could be discharged into the environment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243043,"idioma_id":5,"titulo":"Los Impactos del Turismo en Tupungato: Una mirada sustentable","resumen":"El desarrollo de la actividad turística implica siempre, en mayor o en menor grado, consecuencias para la comunidad local. Las mismas abarcan tres ámbitos específicos: el sociocultural, el ambiental y el económico. Las consecuencias de estos impactos pueden ser positivas o negativas.Desde el concepto de sustentabilidad y turismo se persigue el objetivo de lograr,  a través de una adecuada planificación, el análisis de los impactos y observar las repercusiones en el entorno. Desde la misma óptica, se busca determinar si las mismas son positivas, y en ese caso reforzarlas, o si por el contrario, hay consecuencias negativas de la actividad puedan prevenirse, eliminarse, enfrentarse y minimizarse con la implementación de las estrategias adecuadas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243045,"idioma_id":4,"titulo":"Silent Dissemination of HTLV-1 in an endemic area of Argentina. Epidemiological and molecular evidence of intrafamilial transmission","resumen":"Background: Molecular and epidemiological studies of the transmission routes and risk factors for infection by HTLV-1 are extremely important in order to implement control measures, especially because of the high prevalence of HTLV-1 in several regions of the world. San Salvador de Jujuy, Northwest of Argentina, is a highly endemic area for HTLV-1 and foci of tropical spastic paraparesis\/HTLV-1-associated myelopathy.Objective: To gain further insight into the role of intrafamilial transmission of HTLV-1 in a highly endemic region in Argentina.Method: Cross-sectional study in Northwest Argentina. Epidemiological data and blood samples were collected from 28 HTLV-1 infected subjects (index cases) and 92 close relatives\/cohabitants. HTLV-1 infection was diagnosed by detection of antibodies and proviral DNA. The LTR region was sequenced and analyzed for genetic distances (VESPA software), in addition to determination and identification of polymorphisms to define HTLV-1 family signatures.Results: Fifty seven of the 120 subjects enrolled had antibodies against HTLV-1 and were typified as HTLV-1 by PCR. The prevalence rates of HTLV-1 infection among all family groups and family members of infected index cases were 47.5% and 31.52% (29\/92), respectively. The infection was significantly associated with gender, age and prolonged lactation.Identity of LTR sequences and presence of polymorphisms revealed high prevalence of mother-to-child and interspousal transmission of HTLV-1 among these families.Conclusion: There is an ongoing and silent transmission of HTLV-1 through vertical and sexual routes within family clusters of Argentina. This evidence highlights that HTLV-1 infection must be considered a matter of public health in Argentina, in order to introduce preventive measures as prenatal screening and breastfeeding control.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243046,"idioma_id":4,"titulo":"Environmental Surveillance of Enteroviruses in Central Argentina: First Detection and Evolutionary Analyses of E14","resumen":"Environmental surveillance is an effective approach to investigate the circulation of human enteroviruses in the population. Enteroviruses E14, CVA9, E-6, E16, E20, E25, E13, and CVA24 were detected in sewage and a watercourse in central Argentina. E14 was the most frequent serotype and was found for the first time in environmental samples in our region. Phylogenetic and coalescence analyses showed at least two recent introduction events.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243047,"idioma_id":5,"titulo":"Ciudades obreras y desarrollo. El caso de los poblados de La Forestal.","resumen":"Consecuenciade la confluencia de diversos factoreseconómicos, históricos y políticos, lasciudades obreras cristalizaron un idealde modelo económico que en territoriochaqueño cobró especial importancia en sudesarrollo.&nbsp; La Compañía&nbsp; LaForestal en el &nbsp;Área Metropolitana del Gran Resistencia(AMGR),&nbsp;impulsó un modelo espacial en el que las teorías desarrollistas pudieronconcretarse y reproducir un modelosocio-económico.El objetivo es explicar lainfluencia del sistema de mercado practicadoen La Forestal, con susconsecuencias en la sociedad y el ambiente, visiblesen&nbsp; la planificación urbana.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243057,"idioma_id":5,"titulo":"Validación de la Escala de Depresión Posnatal de Edimburgo (EDPE) en una Maternidad Pública","resumen":"EDPE es un cuestionario que contempla 10 preguntas cerradas sobre síntomas característicos de un estado depresivo mayor, incluida la ideación suicida. El objetivo de este trabajo fue analizar la consistencia interna, validez y número de dimensiones del EDPE.  Se realizó un estudio descriptivo de corte transversal en 99 voluntarias puérperas que concurrieron a una Maternidad Pública. El estudio psicométrico consistió en cálculo de &#945;-Cronbach, análisis factorial de componentes principales, con rotación ortogonal de tipo Equamax y cálculo de la medida de Kaiser-Meyer-Olkin de adecuación de muestreo y prueba de Bartlett. Se encontró: Consistencia interna: &#945;-Cronbach=0.762; Adecuación del muestreo: Kaiser-Meyer-Oldin=0.771; Bartlett: Chi-cuadrado=172.78, p<0,0001. Matriz de factor rotado: 2 dimensiones factoriales (Dimensión 1: Preguntas 3 - 8; Dimensión 2: Preguntas 1, 2, 9 y 10). Siendo: P1: He podido reír y ver el lado bueno de las cosas; P2: He mirado al futuro disfrutando las cosas; P3: Me he culpado sin necesidad cuando las cosas han salido mal; P4: He estado ansiosa y preocupada sin motivo; P5: He sentido miedo o pánico sin tener motivo; P6: Las cosas me abruman; P7: Me he sentido tan infeliz que he tenido dificultad para dormir; P8: Me he sentido triste y desafortunada; P9: He estado tan infeliz que he estado llorando; P10: He pensado en hacerme daño a mí misma. Se concluye que esta versión de la EDPE, con validación transcultural y semántica previa, es un instrumento válido y confiable, de fácil aplicación por el equipo de salud para la detección de depresión posparto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243058,"idioma_id":4,"titulo":"Saccharification of citrus wastes by immobilized polygalacturonase in an improved alginate matrix","resumen":"Enzyme immobilization using hydrogels is a low-cost and effective system for the degradation of bulk pectin derived from orange industry residues. Polygalacturonases obtained from four different bacterial strains of Streptomyces genus were immobilized in alginate gel and assayed for pectin hydrolysis. The enzyme from Streptomyces halstedii ATCC 10897 proved to be superior and more stable within the alginate matrix. Furthermore, a new strategy to improve alginate bead stability using a mixture of calcium and strontium is reported; this technique allowed enhancing the mechanical properties by combining different amounts of these cations for ionotropic gelation. The developed biocatalyst showed maximum hydrolysis at 2 h, generating 1.54 mg\/mL of reducing sugars and decreasing the viscosity of polygalacturonic acid by 98.9%. Reusability up to 29 successive reactions (58 h) demonstrated a very stable performance. The heterogeneous biocatalyst was used in the enzymatic sacchari&#64257;cation of orange peel albedo (2.23 mg\/mL) for adding value to this agro-waste by industrial exploitation.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243060,"idioma_id":4,"titulo":"Active films based on thermoplastic corn starch and chitosan oligomer for food packaging applications","resumen":"Antimicrobial biodegradable films based on thermoplastic corn starch (TPS) and chitosan oligomers (CO) were obtained in order to develop a package prototype for perishable food products. Active films were fabricated thermo-compressing a sandwiched structure constituted by a thin layer of an oligomers enriched solution between two TPS films, previously made by melt-mixing and hot-pressing. Regarding enriched solution, it was obtained by dissolving oligomers in diluted acetic acid. Final material was characterized, determining its physical and optical properties, as well as, studying its microstructure. By diffusion assays it was demonstrated the capability of CO to migrate from the active film towards the aqueous simulant media. Moreover, oligomers were able to diffuse from the matrix, regardless the aqueous medium acidity. Experimental data of diffusion assays were fitted using a mathematical model, estimating diffusion coefficients at three studied pH values (3, 5, and 7). Active film was used to obtain sachets to package perishable foods such as strawberries, ricotta, and flavoredbreads, which were stored for 7 days under controlled conditions. Antimicrobial capacity of active sachets was corroborated through molds and yeast counts in the stored food products. Additionally, it was demonstrated that CO incorporation to the packaging material resulted in a more efficient way to inhibit microbial development than the spraying technique.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243061,"idioma_id":5,"titulo":"Películas biodegradables con actividad antimicrobiana","resumen":"Una de las líneas para el desarrollo de envases activos contempla la incorporación de agentes antimicrobia-nos como el quitosano, polisacárido derivado del exoesqueleto de crustáceos. No obstante, su elevada masa molar restringe su difusión desde el envase hacia el alimento por lo que el empleo de oligómeros de caracte-rísticas diferenciales es una alternativa interesante, aún poco investigada. El objetivo de este trabajo fue obtener películas activas a base de almidón de maíz termoplástico (TPS) mediante la incorporación de oli-goquitosanos (OQ, masa molar = 290 g mol-1 y grado de polimerización = 2). Estos materiales fueron obteni-dos mediante termo-compresión en una prensa hidráulica. Se realizaron ensayos de difusión de los OQ desde la matriz de TPS hacia un medio líquido con diferentes grados de acidez (pH = 3, 5 y 7). Las condiciones del medio líquido fueron seleccionadas según la acidez de una amplia variedad de alimentos. A partir de estos ensayos, se demostró la capacidad de difusión de los oligómeros y su dependencia con el pH del medio. La eficiencia de la incorporación de los OQ en el material de envase se comparó con la correspondiente al mé-todo convencional de spray del alimento con una solución del agente activo. La capacidad antimicrobiana de las películas y de las soluciones de OQ se evaluó a partir del recuento de hongos y levaduras, empleando frutillas frescas como alimento de estudio. Los resultados derivados de estos ensayos evidenciaron el carác-ter activo de la película desarrollada, demostrándose además la mayor eficacia del uso de envases activos antimicrobianos, respecto de los métodos convencionales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243064,"idioma_id":4,"titulo":"First record of Macrocybe titans (Tricholomataceae ? Basidiomycota) in Argentina","resumen":"Macrocybe titans is characterized by its remarkable size, the squamose stipe surface, and the pseudocystidia with refractive content. In this paper, we describe and analyze the macro and microscopic features of Argentinian collections of this species, and provide photographs of its basidiomata and drawings of the most relevant microscopic structures. In addition, we present a map with the American distribution of M. titans, highlighting the first record of this species for the country.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243066,"idioma_id":4,"titulo":"Infructescence traits, floral visitors and seed production of Aechmea distichantha Lem. plants growing in different habitats of a South American xerophytic forest","resumen":"Aechmea distichantha, a widely-distributed facultative epiphytic bromeliad species, is present from rainforests to xerophytic forests. At its southernmost distribution (Humid Chaco) it grows in the understory and forest edges. This animal-pollinated bromeliad shows high phenotypic plasticity on its vegetative traits, but there is no information about plasticity on its reproductive traits. Infructescences from shade plants were heavier, had longer rachis, more spikelets, higher number of fruits\/spikelet and higher number of seeds\/fruit than those from sun plants, but they presented similar number of open flowers. The number of visitation events was similar in both habitats, but more flowers were visited in the sun than in the shade. Flowers were visited by seven species (six insects and one hummingbird). In the sun, the carpenter bee was the most frequent visitor and visited almost all flowers, whereas in the shade different species of visitors attained similar proportion of visits and number of visited flowers. Despite visitation events were similar in both habitats, plants growing in the shade set more seeds\/fruit than plants growing in the sun. The higher proportion of visits accomplished by carpenter bees compared to hummingbirds is probably a consequence of the climatic conditions in the austral location of these populations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243069,"idioma_id":4,"titulo":"Infructescence size has a larger effect than light environment on the abundance of different arthropod feeding guilds dwelling on the infructescences of a terrestrial bromeliad in a xerophytic forest","resumen":"ABSTRACT. Bromeliads are a conspicuous feature of many Neotropical xerophytic forests. Bromelia serra is an understory bromeliad living in xerophytic forests of the Humid Chaco, which shows high phenotypic plasticity when exposed to different environmental conditions. Its infructescences carry many fleshy fruits that are colonized by arthropods from different feeding guilds. We used structural equation modeling and redundancy analysis to evaluate the influences of light environment, plant size, and infructescence size on the abundance of five different feeding guilds of arthropods dwelling on the infructescences ('fruit-secretion feeders', 'infructescence-detritus feeders', 'predators', 'pulp feeders' or 'seed feeders'). Plant size was negatively associated with canopy openness, whereas infructescence size was positively associated with plant size. The abundance of all feeding guilds, except fruit-secretion feeders, were positively associated with infructescence size.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243070,"idioma_id":4,"titulo":"Phenotypic plasticity in Bromelia serra Griseb.: morphological variations due to plant size and habitats with contrasting light availability","resumen":"In the understory of the Schinopsis balansae Engl. forests of the Wet Chaco there are dense populations of Bromelia serra. The individuals of this strictly terrestrial bromeliad grow in the sun as well as in the shade of the understory. Studies carried out with a facultative epiphytic bromeliad, Aechmea distichantha Lem., which also lives in the understory of these forests and whose foliar bases form a tank (phytotelmata), showed the existence of differences in plant architecture and biomass allocation due to plant size (apparent phenotypic plasticity) and to environmental conditions (true phenotypic plasticity). Thus, to evaluate whether the architecture and biomass allocation of a strictly terrestrial bromeliad are also affected by habitat and by plant size, we selected 22 plants of B. serra from open areas and 22 from the understory. The selected plants covered the whole range of plant size. For each plant, we characterized its rosette (height, diameter and number of leaves) and measured the length and width of the longest leaf. The plants were split into stem and leaves (sheaths and blades), weighed, and then several biomass allocation indexes were derived. At a similar biomass, plants growing in the sun had shorter leaves, with a lower length: width ratio than those from the understory, but there were no differences between habitats with regard to plant height, diameter or different biomass fractions. These results suggest that B. serra (a strictly terrestrial bromeliad) shows a high apparent plasticity in most variables, but low true phenotypic plasticity in response to environmental differences.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243071,"idioma_id":5,"titulo":"Variaciones anuales (1999-2016) en la abundancia y en los patrones de distribución espacial de flamencos andinos y australes en el sitio Ramsar Laguna Melincué, Argentina.","resumen":"La Laguna Melincué constituye un sitio de importancia para la conservación de los Flamencos Andino y Austral. La topografía, las condiciones ambientales y el grado de antropización favorecen su heterogeneidad espacial. El nivel de la laguna presenta variaciones cíclicas interanuales debido a ciclos macro-climáticos húmedos o secos. En el año 2005, comenzó a bombearse agua de la laguna, provocando cambios en su salinidad. Durante los años 1999-2016 realizamos conteos invernales de ambas especies de flamencos en los distintos sectores del humedal, y registramos variaciones en la cota y la salinidad del agua. Además, registramos el posicionamiento de Flamencos Andinos equipados con transmisores satelitales. Durante este periodo, la cota fluctuó entre 86.1 y 82.3 m s.n.m., y debido al bombeo la conductividad del agua disminuyó marcadamente. Ésta estuvo asociada positivamente con la abundancia del Flamenco Andino y negativamente con la del Austral. Los registros satelitales muestran que los Andinos estuvieron presentes desde julio hasta setiembre, permaneciendo largos periodos en los mismos sectores. El Flamenco Andino tuvo una distribución de individuos concentrada en ciertos sectores, en tanto que el Austral se distribuyó más uniformemente. La abundancia relativa del Flamenco Austral aumentó en los años de cota alta en los sectores Este y Oeste. Para ambas especies aumentó la proporción de individuos presentes en el sector Sur cuando disminuyó el nivel de la laguna. Estos resultados confirman la importancia de la Laguna Melincué para ambas especies de flamencos, a lo largo del tiempo, a consecuencia del tamaño, profundidad y la heterogeneidad de hábitats que presenta.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243073,"idioma_id":4,"titulo":"Fungal Biodiversity Profiles 21&ndash;30","resumen":"The authorsdescribe ten new taxa for science using mostly both morphological and moleculardata. In Basidiomycota, descriptions are provided for Botryobasidium fusisporumsp. nov., B. triangulosporum sp. nov., Cantharellus hydnoides sp. nov. and Hydnumaerostatisporumsp.nov. in Cantharellales; Lactariusrahjamalensis sp. nov. and Russula pseudoaurantiophyllasp.nov. in Russulalesand for Mycena paraguayensiscomb. nov. in Agaricales. InAscomycotaand hyphomycetes, descriptions are provided for Colletotrichumeryngiicolasp.nov.(Glomerellales),Corynesporellaindica sp.nov. (incertae sedis)andRepetophragmazygopetalisp.nov. (Microthyriales).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243074,"idioma_id":4,"titulo":"One-pot biosynthesis of idoxuridine using nanostabilized lactic acid bacteria","resumen":"An efficient bioprocess using immobilized lactic acid bacteria to obtain 5-iodouracil-2&#8242;-deoxyriboside, known as idoxuridine, is reported. This nucleoside analogue is an antiviral agent used in the treatment of viral infections in the absence of efficient vaccines. Idoxuridine conversion was close to 90% in different nonconventional media.A bionanocomposite (alginate-nanoclay) was employed as matrix to stabilize Lactobacillus animalis ATCC 35046 with improved stability in the presence of organic cosolvents. In this study, an eco-compatible and alternative bioprocess to obtain idoxuridine was developed for the first time. The scale-up biosynthesis of idoxuridine afforded a product yield close to 0.4 gr\/L in the presence of 20% of DMSO.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243075,"idioma_id":4,"titulo":"Aging modifies daily variation of antioxidant enzymes and oxidative status in the hippocampus","resumen":"Background Aging is a complex and multifactorial biological process that leads to the progressive deterioration of physiological systems, including the circadian system. In addition, oxidative stress has been associated with the aging of the normal brain and the development of late-onset neurodegenerative diseases. Even though, functional weakening of circadian rhythms and antioxidant function has been observed during aging, the mechanisms by which the circadian system signaling and oxidative stress are interrelated have not yet been elucidated. The objectives of this study were to evaluate the consequences of aging on the temporal organization of the antioxidant defense system and oxidative status as well as to analyze the endogenous clock activity, in the hippocampus of aged rats. Methods Young adults (3-month-old) or older (22-month-old) male Holtzman rats were maintained under constant darkness conditions, during 15 days before the sacrifice. Levels of catalase (CAT) and glutathione peroxidase (GPx) mRNA and activity, reduced glutathione (GSH), lipoperoxidation (LPO) and BMAL1 protein were analyzed in hippocampus samples isolated every 4 h during a 24-h period. Locomotor activity was recorded during 20 days before the experiment. Results Our results show that aging modifies temporal patterns of CAT and GPx expression and activity in the hippocampus in a different way. On the one hand, it abolishes the oscillating CAT expression and specific enzymatic activity while, on the other, it increases the mesor of circadian GPx activity rhythm (p < 0.01). Additionally, we observed increased GSH (p < 0.05) and reduced LPO (p < 0.01) levels in the hippocampus of aged rats. Moreover, the nocturnal locomotor activity was reduced in the older animals in comparison to the young adult rats (p < 0.01). Interestingly, the 22 month-old animals became arrhythmic and showed a marked fragmentation as well as a significant decline in daily locomotor activity when they were maintained under constant darkness conditions (p < 0.05). Aging also abolished circadian rhythms of the core clock BMAL1 protein. Conclusion The loss of temporal organization of the antioxidant enzymes activity, the oxidative status and the cellular clock machinery could result in a temporally altered antioxidant defense system in the aging brain. Learning about how aging affects the circadian system and the expression of genes involved in the antioxidant defense system could contribute to the design of new strategies to improve the quality of life of older people and also to promote a healthy aging.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243076,"idioma_id":4,"titulo":"Daily rhythms of cognition-related factors are modified in an experimental model of Alzheimer's disease","resumen":"The accumulation of amyloid-&#946; (A&#946;) peptides in the brain of Alzheimer disease patients is associated to cognitive deficit, increased oxidative stress, and alterations in the circadian rhythms. Brain-derived neurotrophic factor (BDNF) and Neurogranin (RC3), play an important role in the synaptic plasticity underlying memory and learning. Previously, we observed BDNF and RC3 expression follow a daily rhythmic pattern in the hippocampus of young rats. The objective of this study was to investigate the effects of an intracerebroventricular (i.c.v) injection of aggregated A&#946; peptide (1?42) on temporal patterns of ApoE protein, Bdnf and Rc3 mRNA, lipid peroxidation (LPO) and reduced glutathione (GSH) levels, in the rat hippocampus. We observed an i.c.v. injection of A&#946; aggregates phase shifts daily BDNF and RC3 expression as well as LPO and decreased the mesor of GSH rhythms. ApoE protein levels vary rhythmically throughout the day. ApoE levels increase at ZT 03:39 ± 00:22 in the hippocampus of control rats and at ZT 06:30 ± 00:28 in the treated animals. Thus, elevated levels of A&#946; aggregates, characteristic of AD, altered temporal patterns of cognition related-factors, probably, as a consequence of changes in the daily variation of ApoE-mediated A&#946; aggregates clearance as well as in the 24 h rhythms of the cellular redox state.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243077,"idioma_id":4,"titulo":"An RNA Virome Associated to the Golden Orb-Weaver Spider Nephila clavipes","resumen":"The golden orb-weaver spider Nephila clavipes, known for its sexual size dimorphism, is abundant and widespread in the New World. The first annotated genome of orb-weaver spiders, exploring N. clavipes, has recently been reported. The study, focused primarily on the diversity of silk specific genes, shed light into the complex evolutionary history of spiders. Furthermore, a robust transcriptome analysis provided a massive resource for N. clavipes RNA survey. Here, I present evidence of viral sequences corresponding to the first 10 extant virus species associated to N. clavipes and indeed, nephilids. The putatively new species are linked to ssRNA positive-strand viruses, such as Picornavirales, and to ssRNA negative-strand and dsRNA viruses. In addition, I detected sequence data of new strains of two recently reported arthropod viruses, which complemented and extended the corresponding sequence references. The identified viruses appear to be complete, potentially functional, and presenting the typical architecture and consistent viral domains. The intrinsic nature of the detected sequences and their absence in the recently generated genome assembly, suggest that they correspond to bona fide RNA virus sequences. The available RNA data allowed for the first time to address a tissue\/organ specific analysis of virus loads\/presence in spiders, suggesting a complex spatial and differential distribution of the tentative viruses, encompassing the spider brain and also silk and venom glands. Until recently, the virus landscape associated to spiders remained elusive. The discovered viruses described here provide only a fragmented glimpse of the potential magnitude of the Aranea virosphere. Future studies should focus not only on complementing and expanding these findings, but also on addressing the potential ecological role of these viruses, which might influence the biology of these outstanding arthropod species.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243078,"idioma_id":5,"titulo":"Volvariella (Pluteacae, Basidiomycota) en el Norte de la Argentina","resumen":"Se describen e ilustran tres especies de Volvariella para el Norte de la Argentina: V. taylorii, conocida para las selvas de Yungas y Paranaense; V. subxerophytica, conocida exclusivamente para los bosques xerófilos de la región chaqueña y V. pusilla encontrada en las provincias del Chaco y Tucumán. Las dos primeras se caracterizan por poseer volva castaña grisácea y superficie del píleo fibrillosa mientras que la última se caracteriza por su volva blanca grisácea y superficie del píleo glabra a muy delicadamente fibrillosa. Se registra por primera vez para Argentina a V. taylorii y se amplía el área de distribución de V. subxerophytica para el sector oriental de la región chaqueña. Es importante destacar que V. subxerophytica era conocida sólo por el material tipo y mediante los nuevos ejemplares hallados fue posible mejorar la descripción original.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243081,"idioma_id":5,"titulo":"Régimen de trabajo y participación en los procesos de recuperación de empresas en Argentina en el nuevo siglo","resumen":"p { margin-bottom: 0.25cm; direction: ltr; color: rgb(0, 0, 0); line-height: 120%; }p.western { font-family: 'Times New Roman',serif; font-size: 12pt; }p.cjk { font-family: 'DejaVu Sans','Times New Roman'; font-size: 12pt; }p.ctl { font-family: 'Times New Roman',serif; font-size: 12pt; }Eneste artículo describimos y analizamos procesosde recuperación de empresasdesarrollados en el período 2000 ? 2015.Transcurridauna década de las primeras recuperaciones de empresas, interesaespecialmente analizar y caracterizar procesos que han logradosostenerse con relativa estabilidad durante un período que aquíconsideramos que ha traspuesto el de la estricta recuperación (etapafundacional e incipiente recuperación). Así, centrándonos en lafasede consolidaciónde los procesos, nos preguntamos por las características de  lasformas económicas y las relaciones sociales que efectivamente se hanconsolidado en los procesos  analizados, y por la naturaleza y losalcances de las transformaciones que en ambos (formas económicas yrelaciones sociales) han tenido lugar. Todo ello, nos acerca aconocer si las nuevas configuraciones laborales constituyen unaexperiencia de trabajo socialmentedistinta.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243082,"idioma_id":5,"titulo":"Competencia y comunidad. Acerca de las relaciones sociales en los procesos de recuperación de empresas de Argentina","resumen":"p { margin-bottom: 0.25cm; direction: ltr; color: rgb(0, 0, 10); line-height: 120%; text-align: left; }p.western { font-family: 'Liberation Serif',serif; font-size: 12pt; }p.cjk { font-family: 'Noto Sans CJK SC Regular'; font-size: 12pt; }p.ctl { font-family: 'FreeSans'; font-size: 12pt; }Eneste artículo describimos y analizamos procesosde recuperación de empresasdesarrollados en el período 2000 ? 2015, ocurridos a partir de la quiebrao cierre de una empresa preexistente yladecisión de los trabajadores de continuar con la actividad,asumiendo ellos mismos la gestión de la unidad económica.Transcurridauna década de las primeras recuperaciones de empresas, interesaespecialmente analizar y caracterizar procesos que han logradosostenerse con relativa estabilidad durante un período que aquíconsideramos que ha traspuesto el de la estricta recuperación (etapafundacional e incipiente recuperación). Así, centrándonos en lafasede consolidaciónde los procesos, nos preguntamos porlas característicasespecíficas que asumen los regímenes de trabajo consolidadosen ambas experiencias. Asimismo, buscamos reconocersi estos procesos son portadores de relaciones laborales socialmentediferentes. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243083,"idioma_id":4,"titulo":"Gut permeability  and glucose absorption are affected at early stages of graft rejection in a small bowel  transplant rat model.","resumen":"Intestinal transplantation (IT) faces many challenges, among them, the necessity to early detect rejection processes. Rodent models of IT are used to provide evidence for intervention strategies as well as improve knowledge of small bowel transplant biology. The aim of our study was to determine the kinetics of small bowel rejection using a Heterotopic IT (HIT) model, with emphasis in the characterization of the process using different approaches, including the use of simple functional assays of absorptive and barrier function evaluation that could be eventually translated to the clinic.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243084,"idioma_id":4,"titulo":"NITRIC OXIDE AND CaMKII: CRITICAL STEPS IN THE CARDIAC CONTRACTILE RESPONSE TO IGF-1 AND SWIM TRAINING","resumen":"Cardiac adaptation to endurance training includes improved contractility by a non-yet clarified mechanism. Since IGF-1 is the main mediator of the physiological response to exercise, we explored its effect on cardiac contractility and the putative involvement of nitric oxide (NO) and CaMKII in control and swim-trained mice.IGF-1 increased cardiomyocyte shortening (128.1 ± 4.6% vs. basal; p&#706;0.05) and accelerated relaxation (time to 50% relengthening: 49.2 ± 2.0% vs. basal; p&#706;0.05), effects abrogated by inhibition of: AKT with MK-2206, NO production with the NO synthase (NOS) inhibitor L-NAME and the specific NOS1 inhibitor nitroguanidine (NG), and CaMKII with KN-93. In agreement, an increase in NO in response to IGF-1 (133.8 ± 2.2%) was detected and prevented by both L-NAME and NG but not KN-93, suggesting that CaMKII activation was downstream NO. In addition, we determined CaMKII activity (P-CaMKII) and phosphorylation of its target, Thr17-PLN. IGF-1, by a NO-dependent mechanism, significantly increased both (227.2 ± 29.4% and 145.3 ± 5.4%, respectively) while no changes in the CaMKII phosphorylation site of ryanodine receptor were evident. The improvement in contractility induced by IGF-1 was associated with increased Ca2 + transient amplitude, rate of decay and SR content. Interestingly, this response was absent in cardiomyocytes from transgenic mice that express a CaMKII inhibitory peptide (AC3-I strain). Moreover, AC3-I mice subjected to swim training did develop physiological cardiac hypertrophy but not the contractile adaptation.Therefore, we conclude that NO-dependent CaMKII activation plays a critical role in the improvement in contractility induced by IGF-1 and exercise training. Interestingly, this pathway would not contribute to the adaptive hypertrophy.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243087,"idioma_id":5,"titulo":"Como Pez en el Ojo","resumen":"Paredes Gloria ComoPez en el Ojo&nbsp; caso clínico yfotografía científica. Revista Oftalmología Clínica y Experimental, OCE 10.1 Marzo 2017&nbsp;p 34.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243090,"idioma_id":5,"titulo":"Autopoiésis y poder: De la jerarquía a la trama de la vida.","resumen":"p { margin-bottom: 0.21cm; direction: ltr; color: rgb(0, 0, 0); line-height: 150%; text-align: justify; }p.western { font-family: 'Times New Roman',serif; font-size: 12pt; }p.cjk { font-family: 'Times New Roman',serif; font-size: 12pt; }p.ctl { font-family: 'Times New Roman',serif; font-size: 11pt; }a:visited { color: rgb(128, 0, 128); }a.western:visited {  }a.cjk:visited {  }a.ctl:visited {  }a:link { color: rgb(0, 0, 255); }a.sdfootnotesym-ctl { font-family: 'Times New Roman',serif; }Estetrabajo es parte de un proyecto de investigación cualitativadenominado ?Las concepciones del poder y su incidencia en losprocesos de cambio organizativos? desarrollado en el Área deAprendizaje y Desarrollo Organizacional del Instituto Rosario deInvestigaciones en Ciencias de la Educación (IRICE-CONICET)Argentina. Presentamos aspectos teórico-metodológicos que le dansustento a dicha investigación, el análisis de datos, la discusiónde los resultados y apreciaciones finales. El objetivo de estetrabajo es poner en relación los datos hallados con la perspectivateórica de la Escuela de Santiago,  realizando una especialreferencia al concepto de autopoiésis. Proponemos una concepcióndel poder centrada en el ser y el estar con otros, fundada en unaperspectiva sistémica, biocéntrica  y compleja. ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243091,"idioma_id":4,"titulo":"A matter of hierarchy: activation of orfamide production by the post-transcriptional Gac-Rsm cascade of Pseudomonas protegens CHA0 through expression upregulation of the two dedicated transcriptional regulators","resumen":"In this work, we surveyed the genome of P. protegens CHA0 in order to identify novel mRNAs possibly under the control of the Gac-Rsm cascade that might, for their part, serve to elucidate as-yet-unknown functions involved in the biocontrol of plant pathogens and\/or in cellular processes required for fitness in natural environments. In view of the experimental evidence from former studies on the Gac-Rsm cascade, we developed a computational screen supported by a combination of sequence, structural, and evolutionary constraints that led to a dataset of 43 potential novel mRNA targets. We then confirmed several mRNA targets experimentally and next focused on two of the respective genes that are physically linked to the orfamide biosynthetic gene cluster and whose predicted open-reading frames resembled cognate LuxR-type transcriptional regulators of cyclic lipopeptide clusters in related pseudomonads. In this report, we demonstrate that in strain CHA0, orfamide production is stringently dependent on a functional Gac-Rsm cascade and that both mRNAs encoding transcriptional regulatory proteins are under direct translational control of the RsmA\/E proteins. Our results have thus revealed a hierarchical control over the expression of orfamide biosynthetic genes with the final transcriptional control subordinated to the global Gac-Rsm posttranscriptional regulatory system.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243093,"idioma_id":4,"titulo":"A matter of hierarchy: activation of orfamide production by the post-transcriptional Gac-Rsm cascade of Pseudomonas protegens CHA0 through expression upregulation of the two dedicated transcriptional regulators","resumen":"THE AUTHORS MUZLERA AND SOBRERO CONTRIBUTED EQUIALLY TO THIS WORKIn this work, we surveyed the genome of P. protegens CHA0 in order to identify novel mRNAs possibly under the control of the Gac-Rsm cascade that might, for their part, serve to elucidate as-yet-unknown functions involved in the biocontrol of plant pathogens and\/or in cellular processes required for fitness in natural environments. In view of the experimental evidence from former studies on the Gac-Rsm cascade, we developed a computational screen supported by a combination of sequence, structural and evolutionary constraints that led to a dataset of 43 potential novel mRNA targets. We then confirmed several mRNA targets experimentally and next focused on two of the respective genes that are physically linked to the orfamide biosynthetic gene cluster and whose predicted open-reading frames resembled cognate LuxR-type transcriptional regulators of cyclic lipopeptide clusters in related pseudomonads. In this report, we demonstrate that in strain CHA0, orfamide production is stringently dependent on a functional Gac-Rsm cascade and that both mRNAs encoding transcriptional regulatory proteins are under direct translational control of the RsmA\/E proteins. Our results have thus revealed a hierarchical control over the expression of orfamide biosynthetic genes with the final transcriptional control subordinated to the global Gac-Rsm post-transcriptional regulatory system.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243094,"idioma_id":5,"titulo":"Utilización de microscopia óptica en el campo de la odontología: Cátedra de endodoncia","resumen":"Consideramos que el empleo de MO no cambia las técnicas dentales del operador estudiante o profesional, sino que aporta una precisión en las mismas que facilitan el objetivo de la jerrquización y excelencia en la terapéutica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243095,"idioma_id":5,"titulo":"NOGALICULTURA: IV Simposio Internacional","resumen":"En la Provincia de Catamarca, los días 6 y 7 en la ciudad de Andalgalá y 8 de septiembre en San Fernando del Valle, se llevó a cabo el IV Simposio Internacional de Nogalicultura, organizado por el Gobierno de la provincia de Catamarca, el INTA y el Consejo Federal de Inversiones, en el marco de la Expo Productiva 2017.Se reunieron referentes del sector, productores, profesionales y científicos, empresas de servicio y entidades que integran el cluster nogalero. Se presenta un análisis de las temáticas abordadas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243096,"idioma_id":4,"titulo":"Proton and cesium conductivity in perfluorosulfonate ionomers at low and high relative humidity","resumen":"Nafion exhibits one of the highest proton conductivity at room temperature and it is the standard electrolyte of proton exchange membrane fuel cells (PEMFC). However, the temperature dependence of ionic conductivity of Nation is highly dependent on the measuring conditions and it is still a matter of debate. In the present study, detailed dielectric spectroscopy (DS) measurements in both dry (under N2 flow) and water-saturated conditions were carried out in a broad range of temperature and frequency. Such DS results were correlated to differential scanning calorimetry (DSC) and dynamic mechanical analysis (DMA) data taken in similar conditions. The main results revealed that in samples conditioned in N2 flow (RH ~&nbsp;0%) the transport of both proton and cesium ions is coordinated with the dynamics of Nafion relaxations. In hydrated Nafion (proton form), conductivity measurements at different frequencies revealed two regimes: one at high-frequency, in which the Vogel-Tamman-Fulcher (VTF) law indicates a close relation between the polymer glass transition temperature Tg; and, a second one at low frequency, bearing great similarity to the transport observed in nearly dry samples. The reported experimental results contribute to disentangle the intricate transport properties of Nafion.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243097,"idioma_id":4,"titulo":"Model Based Analysis of Lithium Batteries Considering Particle Size Distribution","resumen":"Performance of lithium ion batteries whose electrodes are composed of particles of different sizes is studied. Simplified model developed in [7] is extended and the simulations are compared with experiments from the literature so as to validate this new model. The differences in current density observed in particles of different sizes, which are in contact, depend on particle size and state of charge. Internal particle to particle discharge currents are observed during relaxation times. A parametric study of the applied current and particle sizes of electrodes is carried out to evaluate cell performance, with emphasis on cell voltage and final capacity measurement. The evolution of reaction rates on the surface of electrode particles and their corresponding states of charge are depicted. An analysis of relaxation times in terms of cell voltage, current density, equilibrium potentials, and overpotentials is included.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243098,"idioma_id":4,"titulo":"Synthesis, characterization and water up take behavior of PVA hydrogel microbeads","resumen":"Poly(vinylalcohol) (PVA) hydrogel microbeads are of great importance in cancer  embolization procedures. The success of PVA hydrogel microbeads as embolization agents depend strongly on the characteristics of the PVA-water mixture.  The majority of published literature routinely examine the chemical characteristics PVA hydrogel microbeads while crucial physical characteristics are only rarely investigated and never incorporated into water up take (WUT) mechanisms. In the present contribution, the WUT, the most important characteristics of PVA hydrogel microbeads intended for use as embolic agents, were investigated incorporating the conditions imposed by the fact of considering the PVA hydrogel as a non-ideal mixture of PVA and water. PVA hydrogel microbeads were obtained by chemical crosslinking of PVA with glutaraldehyde (GA) in emulsion systems. The structure of resulting PVA microbeads was investigated using FT-IR and SEM. The behavior of PVA hydrogel microbeads in water was followed by optical microscopy. Additionally, a WUT model for hydrogels were the polymer and water behave as non-ideal mixtures is presented.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243100,"idioma_id":4,"titulo":"A moving story: Whole-body motor training selectively improves the appraisal of action meanings in naturalistic narratives","resumen":"This study examined whether systematic whole-body stimulation and increased attention to visuospatial motion patterns can enhance the appraisal of action meanings evoked by naturalistic texts. Participants listened to action and neutral (non-action) narratives before and after videogame-based bodily training, and responded to questions on information realized by verbs (denoting abstract and action processes) and circumstances (conveying locative or temporal details, for example). Strategically, we worked with dyslexic children, whose potential comprehension deficits could give room to post-training improvements. Results showed a selective boost in understanding of action information, even when controlling for baseline performance. Also, this effect proved uninfluenced by short-term memory skills, and it was absent when training relied on non-action videogames requiring minimal bodily engagement. Of note, the movements described in the texts did not match those performed by participants, suggesting that well-established effector- and direction-specific language embodiment effects may be accompanied by more coarse-grained sensorimotor resonance, driven by activation of motor and visuospatial sensory systems. In sum, the stimulation of movement-related mechanisms seems to selectively boost the appraisal of actions evoked by naturalistic texts. By demonstrating such links between two real-life activities, our study offers an empirical tie between embodied and situated accounts of cognition.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243103,"idioma_id":4,"titulo":"Benznidazole and Posaconazole in&nbsp;Eliminating Parasites in Asymptomatic&nbsp;T.&nbsp;Cruzi Carriers: The STOP-CHAGAS Trial","resumen":"Background Benznidazole is recommended for treatment of Chagas infection. Effects of combination therapy with benznidazole and posaconazole have not been tested in Trypanosoma cruzi carriers. Objectives The purpose of this study was to determine whether posaconazole alone or combined with benznidazole were superior to benznidazole monotherapy in eliminating T. cruzi parasites measured by real time polymerase chain reaction (RT-PCR) in asymptomatic Chagas carriers. Methods A prospective, multicenter randomized placebo-controlled study was conducted in 120 subjects from Latin America and Spain who were randomized to 4 groups: posaconazole 400 mg twice a day (b.i.d.); benznidazole 200 mg + placebo b.i.d.; benznidazole 200 mg b.i.d. + posaconazole 400 mg b.i.d.; or placebo 10 mg b.i.d. T. cruzi deoxyribonucleic acid was detected by RT-PCR at 30, 60, 90, 120, 150, 180, and 360 days. The primary efficacy outcome is the proportion of subjects with persistent negative RT-PCR by day 180; the secondary outcome was negative RT-PCR at 360 days. Results Only 13.3% of those receiving posaconazole and 10% receiving placebo achieved the primary outcome, compared with 80% receiving benznidazole + posaconazole and 86.7% receiving benznidazole monotherapy (p < 0.0001 vs. posaconazole\/placebo). Posaconazole monotherapy or posaconazole combined with benznidazole achieved high RT-PCR conversion rates during treatment (30 days; 93.3% and 88.9% and 60 days; 90%, and 92.3%) that were similar to benznidazole (89.7% and 89.3%); all were superior to placebo or posaconazole (10% and 16.7%, p < 0.0001). This was not observed at 360 days; benznidazole + posaconazole and benznidazole monotherapy (both 96%) versus placebo (17%) and posaconazole (16%, p < 0.0001). Serious adverse events were rare (6 patients) and were observed in the benznidazole-treated patients. Permanent discontinuation was reported in 19 patients (31.7%) receiving either benznidazole monotherapy or combined with posaconazole. Conclusions Posaconazole demonstrated trypanostatic activity during treatment, but it is ineffective long-term in asymptomatic T. cruzi carriers. Benznidazole monotherapy is superior to posaconazole, with high RT-PCR conversion rates sustained at 1 year. Side effects lead to therapy discontinuation in 32%. No advantages were observed with combined therapy versus benznidazole monotherapy. (A Study of the Use of Oral Posaconazole [POS] in the Treatment of Asymptomatic Chronic Chagas Disease [P05267] [STOP CHAGAS]: NCT01377480)","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243104,"idioma_id":4,"titulo":"Comparative Study and Analytical Verification of PCR Methods for the Diagnosis of Congenital Chagas Disease","resumen":"Congenital infection is currently the first cause of new cases of Chagas disease in Argentina and nonendemic areas worldwide. Its diagnosis is of utmost importance to guarantee curative treatment. To improve such diagnosis, a transfer process of PCR tests to the national laboratory network has been initiated. We performed a comparative study of four PCR assays [two end-point PCR and two duplex real-time quantitative PCR (qPCR) procedures] to detect Trypanosoma cruzi DNA in blood samples. Because satellite DNA and kinetoplastid DNA qPCR methods showed the best performance and the use of two different molecular targets for confirmatory purposes has been recommended, these methods were selected to perform the transfer process and, in consequence, subjected to an analytical verification protocol based on international guidelines. The anticipated reportable range was verified between 0.25 and 105 parasite equivalents per milliliter of blood (par. eq.\/mL) for both qPCR methods, and the limit of detection was estimated to be 0.87 (95% CI, 0.62?1.24) and 0.43 (95% CI, 0.32?0.59) par. eq.\/mL for satellite DNA and kinetoplastid DNA qPCR methods, respectively. In addition, both qPCR methods showed trueness and verified precision in the highest and the lowest concentrations tested. This work provides critical knowledge of the technology transfer process planned to cover laboratories of the regional network with known installed facilities.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243106,"idioma_id":4,"titulo":"Cyclodextrine-nanoencapsulation of niclosamide: Water solubility and meaningful enhancement of visible-light&mdash;Mediated sensitized photodegradation of the drug","resumen":"A kinetic and mechanistic study of the daylight-mediated photooxidation of the multifunctional drugNiclosamide (NSD) was carried out in aqueous solutions. NSD is a frequent contaminant suspended innatural waters. The aqueous dissolution of the practically insoluble NSD was driven by the presence of2-hydrxypropyl-b-cyclodextrin (HPbCD). The already proposed formation of an inclusion complexbetween NSD-HPbCD was confirmed through theoretical studies. NSD-nanoencapsulation within theoligosaccharide occurs with a 1:2 stoichiometry, being the drug embedded into a cavity of two HPbCDmolecules, in a so called head-to-head orientation.The Reactive Oxygen Species singlet molecular oxygen, superoxide radical anion and hydrogenperoxide, generated through the visible-light absorber sensitizers Riboflavin and Rose Bengal, areeffectively intercepted by the encapsulated biocide and contribute to its photodegradation. The overallNSD photooxidation rate, determined through oxygen consumption indicates that the process isrelatively highly efficient in the microheterogeneous aqueous media as compared to NSD in MeOHsolution, and to phenol (PHE) in pure water. The paradigmatic water-contaminant PHE was taken a asreference in order to evaluate the persistence of the NSD under photosensitized irradiation in aqueousmedium. The photooxidation mechanism of NSD is affected by cyclodextrin complexation, due todynamic limitations, electrostatic interactions and pH changes upon NSD dissolution in aqueous HPbCD.In this sense, the NSD-HPbCD complex can be seen as a sort of nanoreactor that enables thephotodegradation of the biocide in water, under daylight conditions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243107,"idioma_id":5,"titulo":"Mejoramiento del desempeño térmico de sistemas de construcción no convencional en el NEA: evaluación y propuesta de atenuación de puentes térmicos","resumen":"Análisis y diagnostico de la problemática de los puentes térmicos en los volúmenes edificados en el NEA.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243112,"idioma_id":5,"titulo":"Hábitat, producción y ciudad: desafíos y soluciones a la crisi(s) socio-ambiental Polo Cooperativo de Innovación Inclusiva en San Juan, Argentina","resumen":"Este artículo problematizará la noción de crisis y hábitat en vistas a latransformación socio ambiental y aportará el análisis de una propuesta desolución como es la creación de un PCII en la ciudad de San Juan, Argentina.El hábitat como espacio construido permite la residencia y la autoreproducciónsocial. En el caso de Argentina, la producción de viviendas para el logro deese hábitat ha desempeñado un importante rol, no solo como sostén de la actividad económica y de los niveles de empleo, sino también como&nbsp; factor de producción de espacio urbano.La crisis político, social y económica de 2001 en Argentina, intensificó el problemadel déficit habitacional en amplios sectores de la sociedad. A partir de 2003se comenzaron a buscar soluciones habitacionales mediante laconstrucción de nuevos barrios para relocalizar villas de emergencia. En este proceso, la perspectiva economicista en laproducción pública de hábitat produjo tres procesos concatenados: el &nbsp;crecimiento de las periferias urbanas, la segregación de la población de menores recursos y problemas en la búsqueda de empleo. Una alternativa para lasubsistencia en el nuevo hábitat resultó ser la autogestión del empleo, através de la conformación de cooperativas. En ellas han participado una amplia constelación de organizaciones sociales. Sin embargo, un freno para sudesarrollo ha sido el débil nivel de organización y la alta dependencia del Estadomunicipal para su subsistencia. El reciente surgimiento de un Polo Cooperativo de Innovación Inclusiva (PCII) conla participación ampliada de universidades, Estado, ONG y empresas privadas esuna respuesta a esos problemas y estimulalas relaciones sinérgicas entre comunidad y actividades productivas siendo a lavez una oportunidad para repensar las políticas públicas de vivienda concriterios de Buen Vivir.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243113,"idioma_id":4,"titulo":"Comparative study of the phase stability in SrTaO2N","resumen":"Recently, ferroelectric behavior was observed in compressed SrTaO2N thin films epitaxially grown on SrTiO3substrates. Piezoresponse force microscopy measurements revealed small domains (101?102nm) that exhibitedclassical ferroelectricity, a behavior not previously observed in perovskite oxynitrides. The surrounding matrix regionexhibited relaxor ferroelectric-like behavior. Bulk SrTaO2N samples do not show ferroelectricity, thus suggesting thatthe origin of it may be related with the strain induced by the substrate. Ab-initio calculations reported that the smalldomains and the surrounding matrix had trans-type and a cis-type anion arrangements, respectively, but do not describethe experimentally observed equilibrium phase, nor the strain dependent polarization. In this work, we present highaccurate all-electron first-principles calculations on the different possible local structures that can explain theferroelectric-like properties of the strained material. The determined local structure and oxygen\/nitrogen ordering hasbeen related with polarization and epitaxial strain. The potential energies and polarization as functions of the in-planelattice constant are reported.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243114,"idioma_id":5,"titulo":"De la ficción al contexto","resumen":"Los universos ficcionales forman parte de la cultura y con ello modifican las existencias de los sujetos sociales. Cada sociedad construye sus mitos, historias, relatos y le otorga un lugar a su ficción. En la antigüedad clásica, por ejemplo, la tragedia y la comedia griegas tenían un lugar disciplinador para el espectador, quien experimentaba ?en palabras aristotélicas? una catarsis: esa conjunción entre terror de que a uno le suceda lo que al protagonista y a la vez sentir compasión por aquel sujeto trágico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243118,"idioma_id":5,"titulo":"Hacia una consolidacion de la teoria general del derecho notarial justo","resumen":"TEoria general del derecho notarial y la justicia","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243120,"idioma_id":4,"titulo":"Synthesis, Structural Characterization and Biological Evaluation of Rhenium(I) Tricarbonyl Complexes with &beta;-Carboline Ligands.","resumen":"Two b-carboline rhenium(I) complexes, fac-[Re(CO)3(dppz)(nHo)]O3SCF3 and fac-[Re(CO)3(nHo)2Cl] where dppz=dipyrido[3, 2-a:2?,3?-c] phenazine and nHo=9H-pyrido[3, 4-b]indole (norharmane), have been synthesized. These complexeswere fully characterized by structural X-ray diffraction, 1H and13CNMR, UV-vis absorption and FT-IR spectroscopy and massspectrometry. Ground state geometry optimization was carriedout in vacuo with the PBE0 hybrid functional using theLanL2DZ basis set. The characterization was complementedwith TD-DFT calculations using several hybrid functionals.Cellular uptake and cytotoxic effect of both complexes againsthuman lung carcinoma (A549) cells were evaluated. Forcomparative purpose, two related fac-[Re(CO)3(L)(nHo)]+ complexes(L=bpy and phen) were included in the biologicalstudies. The anti-proliferative effect of the compounds wasrationalized in terms of the different extension of the ligands psystem.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243121,"idioma_id":5,"titulo":"Reutilización de las proteínas del suero de quesería para el desarrollo de películas comestibles activas","resumen":"En el presente trabajo se estudió el efecto de la incorporaciónde extracto vegetal con características antioxidantes a la formulación de películas comestibles en base a proteínas de suero de queso sobre el color, la humedad, la densidad,las propiedades mecánicas y la liberación de compuestosreductores de las mismas. Las películas fueron elaboradas en base a proteína de suero de quesería concentrada (WPC) y plastificadas con glicerol (Gly). Elextracto antioxidante de brotes de soja (ELBS) fue adicionado a tres niveles. Las películas fueron preparadas por moldeo y secado. Los resultados obtenidos indicaron que la humedad y la densidad de las películas no se vieron afectadassignificativamente (p<0,05) por la adición de ELBS. El color y las propiedades mecánicas solo fueron afectados significativamente por el nivel mayor de ELBS. Por último, se observó una mayor liberación de compuestos reductores desde la película con adición de ELBS. Por lo tanto, las películas proteicas pueden incorporar a su formulación una cantidad determinada de ELBS sin producirmodificaciones considerables en la apariencia y en las propiedades mecánicas, incrementando la liberación de compuestos reductores hacia sistemas acuosos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243123,"idioma_id":5,"titulo":"Evaluación, calidad y mejora de la educación: aproximaciones críticas","resumen":"A más de veinte años de intensificación de los procesos de evaluación en la educación superior universitaria vale la pena interrogarse sobre su rol en el mejoramiento de la educación.  No obstante, las respuestas no son sencillas porque junto a su ubicuidad, la evaluación ha adoptado matices diferenciales que implican diversos niveles de complejidad y disimiles condiciones de implantación, ocasionando una variedad y multiplicidad de efectos. Esta exposición presenta un conjunto de aproximaciones críticas a la pregunta señalada asumiendo como presupuesto inicial que la contestación es y seguirá siendo objeto de debate tanto en el campo de las políticas públicas como en el de la producción académica. El trabajo se organiza en cuatro apartados. En el primero se analiza el carácter controversial de los conceptos evaluación y calidad así como su relación con el mejoramiento de la educación como marco general para la presentación de la problemática. En la segunda parte se circunscribe el análisis al lugar que ha ocupado la calidad y su evaluación en la Conferencia Regional de Educación Superior 2008, teniendo en cuenta, además, la importancia de estas ideas en declaraciones anteriores. El tercer apartado recorta uno de los ámbitos de la educación superior universitaria, el posgrado, con el propósito de determinar los alcances y límites de la regulación de este nivel educativo a través de la evaluación en un contexto de rápido crecimiento a partir de la década de 1990. Cabe destacar que se referencian países como Argentina, Brasil, Chile y Paraguay. Finalmente, se incluyen reflexiones finales con vistas a establecer un balance sintético y abierto en torno a las complejas relaciones entre evaluación, calidad y mejora educativa.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243124,"idioma_id":5,"titulo":"La predicción afectiva positiva como factor de protección socioemocional en madres transnacionales antes y después de la reagrupación familiar: relación con la satisfacción con la vida, regulación emocional, soledad social, resiliencia y estrés","resumen":"la predicción afectiva es un proceso de sobrestimación emocional previo a un acontecimiento. suele asociarse a altas expectativas y a un coste socioemocional posterior. para estudiar las diferencias entre las predicciones afectivas antes y después de la reagrupación familiar transnacional, se analizan a 188 madres inmigrantes residentes en españa, bien expectantes por reagrupar, bien reagrupadas con sus hijos. se hipotetiza y confirma que existen diferencias estadísticamente significativas antes y después en relación a satisfacción con la vida, control emocional, resiliencia, estrés y soledad social.además, se, resalta la función positiva del pronóstico afectivo en el ajuste socio cognitivo de las madres transnacionales. previamente al evento, este media entre la satisfacción y la sol edad social, y después de la reagrupación, tiene una función mediadora entre la satisfacción vital y el descontrol emocional asociado al encuentro lo que expresa su papel protector en la conciliación familiar.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243125,"idioma_id":5,"titulo":"Funcionalización de leche de búfalas (bubalus bubalis) de la región nordeste de la argentina como estrategia para la valorización del recurso","resumen":"El objetivo de este trabajo fue evaluar el impacto de la suplementación en la alimentación de búfalas sobre la composición basal de su leche. En particular, se examinó el aumento en la concentración de compuestos bioactivos presentes en forma natural (CLA, ácidos grasos omega 3 y omega 6). Se encontró que la ingesta de materias primas ricas en ácidos grasos poliinsaturados condujo a cambios favorables en la proporción de ácidos grasos con actividad nutracéutica. La obtención de leches con propiedades mejoradas podría redundar en subproductos y derivados lácteos con una calidad nutritiva diferenciada, permitiendo extender y diversificar el aprovechamiento de este recurso y captar un mercado creciente, demandante de productos saludables dotados de gran funcionalidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243132,"idioma_id":4,"titulo":"Rebuilding a statistical apparatus at a critical juncture. Argentina and Brazil, from the Great Depression to the Post-World War II period","resumen":"Amidst the political and economic tensions that culminated in World War II, within a few years of each other, the Brazilian and Argentine States embarked on significant reforms of their statistical services. In Brazil, the reform gave rise to a new and completely original statistical institution. Argentina, under the pressure of similar statistical challenges, launched a number of failed reorganization attempts. The goal of this article is to analyze and compare the restructuring of both statistical apparatuses. This paper explores how the pillars of the edifice of public statistics in each country were historically constructed, in order to understand the basis of its social legitimacy and credibility.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243133,"idioma_id":5,"titulo":"Curricularización de la Extensión. Compromiso académico y social sin fronteras","resumen":"Se propone un breve análisis de diferentes argumentos de autores quehan abordado el concepto de la Extensión Universitaria poniéndolos endiálogo con un Proyecto desarrollado en 2016. Se abordará el conceptode curricularización de la extensión; la misma comienza en las accionescomprometidas socialmente de los sujetos involucrados.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243135,"idioma_id":4,"titulo":"Reproductive health and Bolivian migration in restrictive contexts of access to the health system in Córdoba, Argentina","resumen":"Although issues of health have been thoroughly analysed in thefield of migration studies, there are still very few studies that seekto understand the reproductive health of women in migratoryprocesses. This article analyses the reproductive health of Bolivianmigrant women living in the city of Córdoba, Argentina, throughan analysis focused on the community assets that migrantsdeploy in the health-disease-care process within restrictivecontexts of access to the health system. The research consisted ofan exploratory study using in-depth interviews with Bolivianmigrant women and health professionals through theimplementation of semi-structured guidelines. The work showsthat, in an environment characterised by a health system that actsto exclude, migrant women develop a series of rational strategieswhere they draw on community assets embodied in forms of selfcare of the body and in community networks. Based on a processof reframing memories related to health practices in the Andeanworld, these women incorporate these assets and more easilyconfront the obstacles that they must overcome as migrants indifferent stages of their reproductive health.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243136,"idioma_id":10,"titulo":"Migración, salud y género: abordajes de proveedores de salud en la atención de mujeres migrantes bolivianas en la provincia de Mendoza, Argentina","resumen":"Resumen. Si bien la articulación entre migración internacional y salud ha ido en aumento en la literatura, son incipientes aún los estudios interesados en analizar cómo los sistemas sanitarios responden a la atención de mujeres migrantes. Este artículo analiza las opiniones de proveedores de salud en relación a la atención ofrecida a mujeres migrantes bolivianas en la provincia de Mendoza, Argentina. Se trata de un estudio exploratorio y descriptivo con base en entrevistas en profundidad y grupos focales realizadas a personal sanitario. El trabajo muestra distintos tipos de abordajes en la atención de las mujeres migrantes que varían entre aquellas donde se reproducen prácticas de disciplinamiento y control hacia otras donde que se recuperan las condiciones objetivas e históricas donde las mujeres desarrollan sus procesos de salud y los factores culturales, laborales y de género que las atraviesan en el contexto migratorio.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243137,"idioma_id":4,"titulo":"Assessment of the potential utility of different regions of Streptococcus uberis adhesion molecule (SUAM) for mastitis subunit vaccine development","resumen":"Streptococcus uberis is one of the most prevalent pathogens causing clinical and subclinical mastitis worldwide. Among bacterial factors involved in intramammary infections caused by this organism, S. uberis adhesion molecule (SUAM) is one of the main virulence factors identified. This molecule is involved in S. uberis internalization to mammary epithelial cells through lactoferrin (Lf) binding. The objective of this study was to evaluate SUAM properties as a potential subunit vaccine component for prevention of S. uberis mastitis. B epitope prediction analysis of SUAM sequence was used to identify potentially immunogenic regions. Since these regions were detected all along the gene, this criterion did not allow selecting a specific region as a potential immunogen. Hence, four fractions of SUAM (-1fr, 2fr, 3fr and 4fr), comprising most of the protein, were cloned and expressed. Every fraction elicited a humoral immune response in mice as predicted by bioinformatics analysis. SUAM-1fr generated antibodies with the highest recognition ability towards SUAM native protein. Moreover, antibodies against SUAM-1fr produced the highest proportion of internalization inhibition of S. uberis to mammary epithelial cells. In conclusion, SUAM immunogenic and functionally relevant regions were identified and allowed to propose SUAM-1fr as a potential candidate for a subunit vaccine for S. uberis mastitis prevention.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243138,"idioma_id":4,"titulo":"Christian Metz and the mediatization","resumen":"Este artículo se refiere a el estatuto de los estudios de Christian Metz en relación con el tópico de la mediatización. La discusión se extiende sobre la pertinencia metodológica de acceso al fenómeno de la mediatización y sus vinculaciones con los desarrollos propios de Metz a todo lo largo de su trabajo; desde las expresiones iniciales a fines de la década del sesenta hasta sus trabajos póstumos de los primeros años de la década del noventa. A este respecto se destaca la consistencia de esa obra y, en especial, la atención que en nuestros días se hace necesario prestar a sus desenvolvimientos para acercarse de una manera segura a los fenómenos emergentes propios de nuestros días.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243139,"idioma_id":5,"titulo":"Situación de salud de las y los adolescentes de entre 10 y 19 años en Argentina, 2005-2016","resumen":"El abordaje específico del Programa Nacional de Salud Integral en la Adolescencia del Ministerio de Salud de Argentina obligó a compilar y sistematizar la información disponible en ese campo. La publicación en 2016 de la obra Situación de salud de las y los adolescentes en Argentina plantea un panorama dedesafíos sobre los cuales deben diseñarse las políticas de salud","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243140,"idioma_id":5,"titulo":"Condiciones hidrogeomorfologicas en el Área Metropolitana del Gran Resistencia, Provincia del Chaco, República Argentina","resumen":"El presente trabajo estudia las condiciones hidrogeomorfologicas distintivas del sitio sobre el cual se desarrolla el Área Metropolitana Gran Resistencia (AMGR) desde el encuadre disciplinar de la Geografía. Para ello, se parte de la hipótesis que el fenómeno de la expansión urbana esta condicionado por la dinámica del sistema hidrogeomorfologico, el cual define la traza, comportamiento y posibilidades de crecimiento de la ciudad, dando lugar a problemáticas relacionadas con la degradación de los entornos y vulnerabilidad de la población.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243141,"idioma_id":5,"titulo":"Nódulos linfáticos parietales en inspección rutinaria de caprinos","resumen":"El presente trabajo tuvo como objetivo identificar ydescribir los nodulos linfaticos de los caprinos, para establecer criteriossanitarios en el control de carne destinada al consumo. Se abordó la situación,forma y tamaño de los nódulos linfáticos (NL). Seutilizaron seis ejemplares adultos. Previa anestesia general, se realizó laeutanasia e inyección de tinta china a fin de que el drenaje linfático fueravisible en la disección. Se observó que el NL cervical superficial o preescapular, de forma elíptica, se situó en el borde craneal de la escápula. LosNL sub-ilíacos o pre-femorales, alargados, se situaron en craneal del músculotensor de la fascia lata, equidistantes de la patela y el tubérculo coxal. ElNL retro mamario, ovalado, se localizó en la región inguinal, rodeado deabundante cantidad de grasa. El NL poplíteo, de forma ovoide, se ubicó entre los músculos bíceps femoral y el contornocraneal del músculo semitendinoso. El NL prepectoral, costo cervical o falso ganglio del inspector, de forma alargada, se halló a lo largode la superficie ventral de la tráquea. El NL ilíaco medio, conforma de coma, se ubicó cerca de la bifurcación de la aorta abdominal. El NLilíaco lateral, redondeado, se situó en lateral del origen de los vasos ilíacosexternos. A los NL isquiáticos, de forma ovoide, se los localizó en la incisuraisquiática mayor, en craneal de la cresta isquiática. Los resultados difierende los descriptos en esta especie por otros autores, en cuanto al número y tamañode determinados linfocentros. El hallazgo permitirá adecuar los sistemas devigilancia durante la inspección de rutina en la playa de faena y mejorar lacalidad de los alimentos que llegan al consumidor.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243145,"idioma_id":4,"titulo":"Proliferation-apoptosis balance in Staphylococcus aureus chronically infected bovine mammary glands during involution","resumen":"The objective of this study was to determine whether Staphylococcus aureus chronic intramammary infection (IMI) influences expression of proteins related to regulation of proliferation and apoptosis processes and proliferation\/apoptosis index during active involution in bovine mammary gland. Twenty-one Holstein non-pregnant cows in late lactation either uninfected or with chronic naturally acquired S. aureus IMI were included in this study. Cows were slaughtered at 7, 14 and 21 d after cessation of milking and samples for immunohistochemical analysis were taken. Protein expression of Bcl-2, Bax, Fas and active caspase-3 in mammary tissue was significantly affected by chronic S. aureus IMI, all showing increased immunoexpression in S. aureus-infected quarters at all involution stages. The percentage of apoptotic cells was increased by IMI in both mammary parenchyma and stroma, and the percentage of parenchymal and stromal cell proliferation was also increased. The proliferation\/apoptosis ratio was significantly increased by IMI only in stromal cells. This imbalance to favour proliferation in S. aureus-infected mammary quarters could be one of the underlying causes that induce aberrant involution with permanence of nonsecretory tissue and increase of stromal components.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243146,"idioma_id":5,"titulo":"Las políticas de formación docente en Argentina: de la tecnocracia de los ´90 a la 'ceocracia' actual","resumen":"Las políticas destinadas a regular la formación y el trabajo docente constituyen uno de los aspectos clave en todas las propuestas de reforma de los sistemas educativos. En este artículo analizamos las orientaciones de política para la formación docente que se implementaron en Argentina durante el período 2003-2015 (gobiernos kirchneristas), identificando cambios y permanencias respecto de las políticas hegemónicas durante la década de los años ´90. Asimismo incluimos algunas de las transformaciones en curso a partir de la llegada de la Alianza Cambiemos al gobierno en diciembre de 2015.Para ello, primero describimos algunas notas distintivas del sistema formador en su construcción histórica para dar cuenta de la complejidad del campo de la formación docente en Argentina. Luego, analizamos la lógica tecnocrática e instrumental que orientó las políticas hacia el sector docente en el contexto de la autodenominada transformación educativa de la década de los años 90. En tercer lugar, nos detenemos en las políticas en materia de formación docente impulsadas por los gobiernos kirchneristas (2003-2015) en el marco de las políticas destinadas a la ampliación y materialización de derechos. Por último, presentamos algunas de orientaciones de las políticas del actual gobierno de 'Cambiemos' en un escenario de fuerte descalificación del sector docente y de sus representaciones sindicales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243147,"idioma_id":5,"titulo":"Variaciones eritrocitarias en poblaciones residentes a diferentes niveles altitudinales (Provincia de Jujuy)","resumen":"Más de 200 millones de personas en el mundo habitan en ambientes de altura por encima de los 2500 msnm, de las cuales 3 millones lo hacen en la Argentina. De acuerdo a registros censales para la provincia de Jujuy, el 9% de su población habita en este ambiente en particular, la cual representa un factor evolutivo de gran importancia debido a la permanencia de su acción sobre las poblaciones expuestas a ella y al hecho de que ninguna adaptación cultural o tecnológica permite disminuir o superar sus efectos. Las poblaciones más antiguas que viven en ambientes de altura son las radicadas en el Tibet y en las zonas altas de Etiopía. Con tiempo intermedio de antigüedad se encuentran las poblaciones andinas y de menor antigüedad zonas altas de Norte América y recientemente, se ha estudiado en China, a la etnia Han que habita en el Tibet. El hábitat de estas poblaciones se caracterizan por estar expuestas a diferentes condicionantes como ser hipoxia, gran amplitud térmica, baja humedad relativa, escaso aporte nutricional y alta radiación cósmica(5-6) que se asocian al ambiente de la altura como un complejo fijo de tensiones. Por consiguiente, la evaluación de las poblaciones expuestas a ella genera inicialmente compensaciones fenotípicas y En la presente ponencia nos proponemos evaluar larespuesta hematopoyética en el habitante de altura.Nos referimos específicamente a la respuesta eritropoyética en el organismo, teniendo en cuenta que al momento de definir anemia, según altura sobre el nivel del mar, debe diferenciarse entre ?eritrocitosis fisiológica? (EF) de ?eritrocitosis excesiva? (EE), definiendo esta última como el valor que corresponde a más de dos desvíos estándar del valor medio de la hemoglobina, como sucede en algunas anormalidades genéticas o somáticas, como por ejemplo en la mutación de receptores de eritropoyetina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243149,"idioma_id":4,"titulo":"A Review of Linguistic Policies Related to the Teaching of English From Colonial Times to Present Times in Argentina.","resumen":"ABSTRACT: The study of the evolution of linguistic policies along the course of history helps us understandthe underlying motivations of the decisions taken, and bring light into possible solutions to current problems. InLatin America in general and in Argentina in particular, the development of the ability to communicate inEnglish in scientific studies- Biology, Chemistry, Physics and Mathematics - is little realized during the years atuniversity. In this work, we present a brief journey through the history of linguistic policies in terms of theteaching of second languages in Argentina from colonial times to present times in pursue of understanding thislow degree of realization.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243150,"idioma_id":4,"titulo":"A survey on tomato leaf grey spot in the two main production areas of Argentina led to the isolation of S. lycopersici 6 representatives, which were genetically diverse and differ in virulence.","resumen":"Tomato gray leaf spot was first reported in Argentina in 1990. Since then, the disease has not only increased in endemicc areas , but also disseminated in other tomato-growing areas. In a survey of plantas with typic symptoms of Tomato grey leaf spot disease we isolated 27 Stemphylium representatives representatives from the two main tomato-growing areas of Argentina . Cultural features such as sporulation, conidia morphometry among others revealed high variability between isolates, which was confirmed by Inter simple sequence repeat (ISSR)-PCR technique A molecular phylogenetic analysis comprising the Internal Transcribed Spacer (ITS) and the glyceraldehyde-3-phosphate dehydrogenase (gpd) gene partial sequences unambiguously identified all isolates as Stemphylium lycopersici. Based on disease severity on detached leaves, isolates were grouped in three cathegories high, medium and low virulent one. No correlation was found between phenotypic orgenotypic characters and the geographical origin of the isolates.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243151,"idioma_id":4,"titulo":"Melanins in Fungi: types, localization and putative biological roles","resumen":"Melanin is a secondary metabolite made up by complex heterogeneous polymers. Several classes of fungal melanins have been described like &#947;-glutaminyl-3,4-dihydroxy-benzene (GDHB)-, L-DOPA-(eumelanin), DHN-, catechol-melanin, pyomelanin, p-aminophenol(PAP)-melanin, heterogeneous melanins as well as two others based on 5-deoxybostrycoidin and aspulvinone E. They have been mostly localized in cell walls of different structures of fungi, which suggest that they play a different biological role. They have been related mostly with morphogenesis, stress resistance, virulence and energytransduction. However, an enormous amount of work remains to be done to clarify, among other things, the role melanins play in fungi.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243152,"idioma_id":4,"titulo":"The mitochondrial genome of the plant-pathogenic fungus Stemphylium lycopersici uncovers a dynamic structure due to repetitive and mobile elements","resumen":"Stemphylium lycopersici (Pleosporales) is a plant-pathogenic fungus that has been associated with a broad range of plant-hosts worldwide. It is one of the causative agents of gray leaf spot disease in tomato and pepper. The aim of this work was to characterize the mitochondrial genome of S. lycopersici CIDEFI-216, to use it to trace taxonomic relationships with other fungal taxa and to get insights into the evolutionary history of this phytopathogen. The complete mitochondrial genome was assembled into a circular double-stranded DNA molecule of 75,911 bp that harbors a set of 37 protein-coding genes, 2 rRNA genes (rns and rnl) and 28 tRNA genes, which are transcribed from both sense and antisense strands. Remarkably, its gene repertoire lacks both atp8 and atp9, contains a free-standing gene for the ribosomal protein S3 (rps3) and includes 13 genes with homing endonuclease domains that are mostly located within its 15 group I introns. Strikingly, subunits 1 and 2 of cytochrome oxidase are encoded by a single continuous open reading frame (ORF). A comparative mitogenomic analysis revealed the large extent of structural rearrangements among representatives of Pleosporales, showing the plasticity of their mitochondrial genomes. Finally, an exhaustive phylogenetic analysis of the subphylum Pezizomycotina based on mitochondrial data reconstructed their relationships in concordance with several studies based on nuclear data. This is the first report of a mitochondrial genome belonging to a representative of the family Pleosporaceae.  ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243153,"idioma_id":4,"titulo":"Corynespora cassiicola and Stemphylium lycopersici infected and developed disease on Tomatoes in Argentina","resumen":"Two pathogens were isolated from tomatoes with severe chlorosis and necrosis innorthwestern Argentina. Monosporic cultures were morphologically characterized andmolecularly identified as Stemphylium lycopersici and Corynespora cassiicola. This is the first report of C. cassiicola infecting tomato in Argentina, whose pathogenic role remains unclear.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243154,"idioma_id":4,"titulo":"Sex differences in the development of prolactinoma in mice overexpressing hCGB: Role of TGFB1","resumen":"Female transgenic mice that overexpress the human chorionic gonadotrophin B subunit (hCGB+) develop prolactinomas, whereas hCGB+ males do not. The high levels of circulating hCG induce massive luteinization in the ovary of hCGB+ females, and progesterone becomes the primary steroid hormone produced, but estradiol remains at physiological level. The involvement of high levels of progesterone in lactotroph proliferation is not clearly understood; hence, the pathogenesis of prolactinomas in hCGp+ females remains unclear. TGFp1 is an inhibitor of lactotroph function, and the reduced TGFp1 activity found in prolactinomas has been proposed to be involved in tumor development. The aim of the present work was to study the role of TGFp1 in the gender-specific development of prolactinomas in hCGB+ mice. We compared the expression of different components of the pituitary TGFB1 system in males and females in this model. We found reduced TGFB1 levels, reduced expression of TGFB1 target genes, TGFB1 receptors, Ltbpl, Smad4 and Smad7 in hCGB+ female pituitaries. However, no differences were found between the transgenic and wild-type male pituitaries. We postulate that decreased pituitary TGFB1 activity in hCGB+ females is involved in the development of prolactinomas. In fact, we demonstrated that an in vivo treatment carried out for increasing pituitary TGFB1 activity, was successful in reducing the prolactinoma development, and the hyperprolactinemia in hCGB+ females. Moreover, the stronger TGFB1 system found in males could protect them from excessive lactotroph proliferation. Sex differences in the regulation of the pituitary TGFB1 system could explain gender differences in the incidence of prolactinoma.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243155,"idioma_id":4,"titulo":"Sex differences in the pituitary TGF&beta;1 system: The role of TGF&beta;1 in prolactinoma development","resumen":"Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in tumor size, behavior and incidence have been described. These differences have been associated with earlier diagnosis in woman, as well as with serum estradiol levels. Experimental models of prolactinomas in rodents also show a higher incidence in females, and recent findings suggest that gender differences in the transforming growth factor beta 1 (TGF&#946;1) system might be involved in the sex-specific development of prolactinomas in these models. The aim of this review is to summarize the literature supporting the important role of TGF&#946;1 as a local modulator of pituitary lactotroph function and to provide recent evidence for TGF&#946;1 involvement in the sex differences found in prolactinoma development in animal models.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243156,"idioma_id":5,"titulo":"Estrés percibido, procesamiento de la información, niveles de cortisol y calidad de sueño en niños","resumen":"Se investigaron la percepción de estrés cotidiano, los niveles de cortisol, el procesamiento de la información y la calidad de sueño en niños. Se estudiaron 53 niños escolarizados (66% varones) de 8 a 13 años (Media=10,52; DE=1,36) de la ciudad de San Luis, Argentina. Se utilizaron: a) Inventario Infantil de Estresores Cotidianos; b) batería de evaluación de Kaufman y Kaufman para niños y c) Children?s Sleep Habits Questionnaire versión en español. Los participantes fueron clasificados en dos grupos según el estrés percibido: 1) Estrés Alto: niños con puntajes en el Inventario de estrés superiores a la media más 1 DE, y 2) Estrés Bajo: niños con puntajes inferiores a la media menos 1 DE. El grupo con Estrés Alto mostró menores niveles de cortisol matinal (p=0,050), inferior calidad de sueño (p=0,009) y menor desempeño en las pruebas de la batería de Kaufman y Kaufman repetición de números y orden de palabras (p=0,014 para ambos). Estas pruebas evalúan atención, canales de comunicación audio-vocal, viso-motora y memoria de trabajo auditiva. Las niñas tuvieron mayor percepción de estrés (p=0,004) y menor calidad de sueño (p=0,000) que los varones.De los resultados se infiere que en niños escolarizados el estrés altera el procesamiento de la información secuencial, el ritmo circadiano del cortisol y la calidad de sueño, siendo en esto último mas afectadas las niñas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243157,"idioma_id":4,"titulo":"IUNS. 21st International Congress of Nutrition. Buenos Aires, Argentina, October 15-20, 2017: Abstracts","resumen":"Olive oil as functional food. Scientific evidence in healthFunctional food is defined as all food consumed habitually as part of a normal diet, which independent from the provision of nutrients, contain biologically active components with the capacity to affect positively a particular biological activity, reducing the risk of diseases.  The component which makes some food functional can be either a macro nutrient with a determined physiological effect, or an essential micro nutrient eaten in a dose above the recommended intake. It can also be a non-essential element of the food or a component without any nutritional value. The strategies of functional food production can be varied but these components will always come in the form of some food. In the case of olive oil (OO) both principal components as well as others which are present in small concentrations have been included in this category. It is important to remark that not all OO, considered to be the Mediterranean Diet fat, are equally beneficial to health. The scientific community has unanimously highlighted the beneficial nutritional effects and the healthy attributes of extra virgin olive oil (EVOO) both for its lipid part and its antioxidants. Among the principal components the most important is oleic acid (C18:1, &#969;-9) whose healthy properties have been recognized by the Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). Among the secondary components with bioactive character the phenolic compounds are highlighted by abundant scientific evidence. Nowadays it is also known that the special healthy attributes of OO can be found in the combined and synergic effect between principal and secondary components all of which are present in the fruit, the olives. Consequently, the most recommended olive oil for health will be the one with the highest quality. In this sense, EVOO is the one with the higher potential as a result of the scientific evidence provided by nutritional epidemiology which highlights its importance in relation to the health of its consumers.  The beneficiary effects of olive oil as a functional food in dealing with different pathologies would not be merely due to its content of oleic acid but also due to the participation of polyphenols which act as a defense antioxidant mechanism against the constant production of Free Radicals (FR). These are highly unstable and reactive components which attack other cell components causing harm to proteins, lipids and DNA implied in the origin and evolution of chronic degenerative diseases. There is no data about the secondary components with a bioactive nature of the varities of olive oil obtained in Catamarca, which is considered to be the main producer province of OO in Argentina. All this makes it necessary to carry out more research about the phenolic portion present in olive oils from Catamarca so as to be able to design a functional oil enriched with these bioactive components, in the appropriate doses for the prevention of diseases associated to old age and oxidative stress.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243158,"idioma_id":4,"titulo":"Bird  communities  along  urbanization  gradients:  a  comparative analysis among three neotropical cities","resumen":"Urbanization is expanding continuously over rural and natural areas and it is imperative to analyze its effect on bird communities. Although the impact of urbanization on bird communities in the Neotropical region has been explored by several authors, there is a scarcity of comparative studies with standardized methodologies that allow establishing whether the effects of urbanization are similar in different ecoregions. We analyzed the urbanization impact on bird communities in three Neotropical cities. Cities were located in different biomes: La Paz (Bolivia) surrounded by a highland plateau and inter&#8208;Andean valleys; Mar del Plata (Argentina) surrounded by agroecosystems of the pampas; and Osorno (Chile), surrounded by agroecosystems, timber plantations, and remnants of temperate forests. In general, high levels of urbanization correlated negatively with bird richness in the three cities, but the response of bird richness to urbanization varied among cities, being linearly negative in La Paz and Osorno and declining only towards high levels of urbanization in Mar del Plata. The effect of urbanization was stronger in La Paz, where more bird species were absent toward higher urbanization levels. Bird abundance did not show significant responses to urbanization. Exotic bird abundance showed a positive relationship with urbanization in the three cities. Bird composition differed between cities and urbanization levels. The House Sparrow (Passer domesticus) was the most abundant species in more urbanized sites, the Eared Dove (Zenaida auriculata) in moderate levels of urbanization, whereas the Rufous&#8208;collared Sparrow (Zonotrichia capensis) was most abundant in the less urbanized sites. The results of our study showed that the impact of urbanization on bird communities in the Neotropical region varied among cities, probably as a result of latitude and the structure of rural areas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243159,"idioma_id":4,"titulo":"IUNS. 21st International Congress of Nutrition. Buenos Aires, Argentina, October 15-20, 2017: Abstracts","resumen":"Olive oil: something more than a monounsaturated fatIt is widely accepted that any variety of olives may be used to obtain olive oil; however, the field yields and the quality of the product vary. Each variety of olive produces a different type of oil with its own sensory characteristics that give them their distinctive features. Virgin olive oil are oils obtained from the fruit of olive tree (Olea europaea L.), by mechanical procedures and by some other physical thermalmeans so as to avoid the alteration of the oil with. It means no other treatments apart from washing, decanting, spinning and filtrate. In this process, solvents, chemical refining and additives are excluded. These olive oils are classified with different denominations according to physicochemical and organoleptic parameters. From a chemical point of view oil  contains a principal or saponifiable part, which represents 98-99% of the total weight of oil, and a minority part which represents 2%. The latest innovations in the process and the spreading of extra virgin olive oil (EVOO) culture are based on its quality. There are many studies derived from nutritional epidemiology which support the scientific evidence concerning the portance of EVOO in connnection with the health of its consumers. These oils play a central role in the Mediterranean Diet, and the fact that its habitual consumption is associated to a lower risk of chronic-degenerative diseases.  Among the constituents of the larger part, oleic acid is the principal nutrient, which besides it energetic function. The largest part of the bioactivity of olive oil  (C18:1, &#969;-9) is also atributted to oleic aid. It represents 68-82% of the total amount of fatty acids found in oil. It can be found it its free form, though it maily form part of the oil triacylglycerols. EVOO contain, in their unsaponifiable part, hundreds of minor constituents which are difficult to determine because of their structural complexity and their low concentration; however, they have demonstrated a beneficial effect on people´s health. In this group some compound clases are included which are not chemical related to fatty acids, among which polyphenols with a great structural complexity are worth mentioning. The antioxidant potential of the compounds  allows them to act as defense mechanisms against oxygin reagent species associated to the steady deterioration of the biological systems, even in good living conditions. The molecular  mechanism by which these compounds produce beneficial effects on health is still unknown or difficult to explain.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243160,"idioma_id":5,"titulo":"PRIMER REPORTE DE UN ESTUDIO SEROLÓGICO DE LEPTOSPIROSIS EN GANADO BOVINO Y CAPRINO DE UNA REGIÓN DEL SURESTE DE LA PROVINCIA DE LA RIOJA, ARGENTINA","resumen":"El presente estudio se llevó a cabo en la región de los Llanos Riojanos ubicada alsureste (SE) de la provincia de La Rioja en Argentina. Se analizaron muestras desuero sanguíneo de 166 bovinos y 49 caprinos de diferentes categorías,provenientes de rodeos de la región. El suero sanguíneo límpido fue analizadomediante la técnica del M.A.T (Test de Aglutinación Microscópica). Del total desueros bovinos, se halló una tasa de seropositividad a L. interrogans del 5,42%. Losserovares detectados con mayor frecuencia para esta especie fueron Pyrogenes,Pomona y Hardjo. Dentro de la población de caprinos analizada se obtuvo una tasade seropositividad a L. interrogans del 3,09%. Entre los sueros reactivos losserovares detectados con mayor frecuencia fueron Pomona, Icterohaemorrhagiae yHardjo. Los resultados obtenidos nos permitieron observar que las poblacionesanalizadas de vacas y cabras de la región del estudio son infectadas por lasprincipales serovares de L. interrogans que son endémicas para el ganado enArgentina.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243161,"idioma_id":5,"titulo":"Honey brew, nueva cerveza roja de miel","resumen":"Se presenta nueva alternativa en cerveza roja tipo Ale. Con el agregado de miel.Formulación ensayada65% malta Pilsen20% malta Chocolate15% miel (de orégano destacada por su aroma)Lupulado suave (2 g\/l de lúpulo Cascade) Proceso de elaboración utilizado: Molienda de la malta, Maceración, Filtración del grano, Lavado del grano, Cocción del mosto, (lupulado - agregado de miel), Enfriamiento del mosto, Eliminación de turbios, Aireado, Agregado de Levadura, Fermentación, Tipo Ale (fermentación alta a 18°C), Desborre, Trasiegos, Carbonatación natural(envasado con agregado de miel\/levadura)","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243162,"idioma_id":5,"titulo":"Buscando nuevos aromas y sabores: elaboración de cerveza rubia artesanal con el agregado de pasas de uva","resumen":"Se elaboró una cerveza rubia tipo alé, utilizando pasas de uva. Se logró modificar el perfil sensorial, dando nuevas notas afrutadas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243169,"idioma_id":4,"titulo":"A preliminary study on the non-linear behavior of hypersonic flow","resumen":"This paper aims to identify the chaotic behavior of plasma flow in hypersonic flights from the measure- ments made in a vector of atmospheric sounding. To this end, we analyzed the data obtained from the flight of the SONDA vector for the study of the upper atmosphere (GRADICOM II Project), which was launched on 11 July 2011 by the Instituto de Investigaciones Científicas y Técnicas para la Defensa from the Ministerio de Defensa de la Nación. The vector reached an apogee of 92 km approximately and a maximum speed of 6.56 Mach, presenting plasma formation immediately after entering hypersonic flight. Based on the inertial measurements in the vector?s body, we proceeded to solve the equations of naviga- tion, obtaining the trajectory and speed of the vector together with the transformation matrix between the reference systems, Earth Centered Earth Fixed ?ECEF?and East North Up ?ENU?. After the identifi- cation of the hypersonic flight zone, and from the point of view of the accelerations in ENU reference system, we computed several indexes and verified which were compatible with chaotic behavior using various methods. These results led us to continue our research work in order to better understand this characteristic of hypersonic flight.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243170,"idioma_id":4,"titulo":"Do taxonomic, phylogenetic and functional plant &#945;- and &#946;-diversity reflect environmental patterns in the Lower Paraná River floodplain?","resumen":"Background: Floodplain wetlands feature high plant biodiversity, comprising variability in several organisation levels and at different scales.Aims: In a large river floodplain, we aimed to answer whether taxonomic, phylogenetic and functional &#945;-diversity of herbaceous assemblages responded to hydrogeomorphic features conditioning the local flood pulse and\/or to soil features; and to determine the relationship between &#946;-diversity and geographic and environmental distances.Methods: Taxonomic, phylogenetic and functional &#945;-diversity indices were computed in 82 sites in the Lower Paraná River floodplain. Relationships between &#945;-diversity and environment were explored by generalised linear models. Spatial structure was assessed by semi-variograms. Responses of partitions of &#946;-diversity to geographic or environmental distances were tested through multiple regressions in distance matrices.Results: Taxonomic and phylogenetic &#945;-diversity showed a similar pattern in relation to environment, especially to hydrogeomorphic features. The regression model fitted to species richness had the highest explanatory power. Regarding functional &#945;-diversity, only the number of plant functional types responded to environmental features. Partitions of &#946;-diversity, particularly the replacement of functional strategies, were better explained by environmental than by geographic distances.Conclusions: The diversity patterns of plant assemblages in a large river floodplain highlight the importance of heterogeneity conditioning the local effect of flood pulse regimes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243172,"idioma_id":4,"titulo":"A quasi-Newton modified LP-Newton method","resumen":"We consider a method to solve constrained system of nonlinear equations based on a modification of the Linear-Programming-Newton method and replacing the first-order information with a quasi-Newton secant update, providing a computationally simple method. The proposed strategy combines good properties of two methods: the least change secant update for unconstrained system of nonlinear equations with isolated solutions and the Linear-Programming-Newton for constrained nonlinear system of equations with possible nonisolated solutions. We analyse the local convergence of the proposed method under a standard error bound condition proving its linear convergence for nonisolated solutions. Numerical experiments were done in order to show the claimed convergence rate.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243173,"idioma_id":4,"titulo":"Energy management control design for fuel cell hybrid electric vehicles using neural networks","resumen":"The design and optimization of hybrid electric vehicle powertrains can take a great benefit from mathematical models which include auxiliary management and control strategies of the energy fluxes: the use of virtual platforms reduces the expensive and time-consuming experimental activity. In this work the authors developed an online Energy Management System (EMS) controller for a FCHEV, designed to employ the same energy management over a wide range of driving style types. The controller was designed by using neural networks (NN), which were trained with the optimal power flux distribution between a fuel cell system and a battery system that minimizes the overall equivalent energy consumption. The optimal solution was obtained by carrying out a gradient-based method minimization over eight different driving cycles, and using a dynamic lumped parameter mathematical model of a FCHEV fed by hydrogen and Li-ion batteries. A quantitative and qualitative analysis was made showing the networks performances over different type of cycles. Through this analysis, a suitable classification into two cycle categories is provided, covering most of the possible driving styles with two of the developed controllers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243176,"idioma_id":4,"titulo":"Detection of Lateral Borders on Unmarked Rural Roads","resumen":"This work presents a method to detect roads in rural conditions, considering gravel or stabilized roads. The main features of this type of ways are based on they do not have lanes and either lateral or central delimitations. This type of road is common in several countries that, for their infrastructure road, still have a large percentage considered as belonging to red earth without paving or delineating. In order to detect the edges of the paths, this work proposes ananalysis strategy based on channel selection on HIS color map representation. The selection automatically allows detecting the channel which brings better information. A convolution filter sequence combined with an adaptive HoughTransform is then applied to detect of curves in the way","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243177,"idioma_id":5,"titulo":"Notas en torno al debate estatutario de la Universidad de Buenos Aires (1958\/1960) Sobre la construcción de un débil programa institucional","resumen":"El presente articulo se ocupa de deconstruir el instrumento legal que definió la organización de la UBA y que, con mínimas modificaciones, continúa haciéndolo en el tiempo presente. La palabra ?deconstrucción? ha devenido en un término de sentido común académico, que presupone de antemano a las ideas de crítica y análisis. Deconstruir un texto, proceso o fenómeno supone per se, la condición de hacer una lectura crítica a partir del proceso de separar las partes que componen a ese objeto. La idea de ?deconstrucción? ocupa un lugar central en la propuesta filosófica de Jaques Derrida desde De la gramatología de 1965 (2010). Es una palabra que posee una ubicuidad permanente en la obra del autor, en un texto ?menor? ?que en castellano se incluyó en el volumen El tiempo de una tesis. Deconstrucción e implicancias conceptuales- llamado ?Carta a un amigo japonés? (1997), advierte que la deconstrucción no es ni una analítica ?porque no tiene por propósito reconstruir un texto en elementos aislados-, ni una crítica -en tanto la pregunta por la decisión es una preocupación del autor, pero de la misma manera en que lo hace en toda la filosofía después de Kant -. En último lugar, pero sobre todo, tampoco puede pensársela como una metodología, porque cada ?acontecimiento? a deconstruir es singular e irrepetible.Una lectura deconstruccionista de un texto radica en prestar atención a las zonas marginales en las que la vigilancia del autor sobre el mismo es potencialmente menor, entendiendo a ese texto en un dinámico juego de relaciones intertextuales. En este caso particular, supone reconstruir la textualidad del Estatuto de la UBA a la luz de su debate asambleario y de las condiciones de producción que lo antecedieron, textos que lo enmarcan y dan sentido histórico. La lectura que proponemos del Estatuto no es otra que la de analizar el fundamento condensado en sus 124 artículos a partir de las discusiones plasmadas en las actas mecanografiadas de las sesiones de la asamblea destinada a sancionar una norma legal que rigiera a toda la UBA, para ver la forma en que determinadas visiones sobre la universidad pública se desplazaron en el texto institucional con una fuerza capaz de delimitar un programa institucional (Carli, 2008) para esa Universidad, pero que ese programa se caracterizó por su debilidad, por ser un texto que se propuso contener la capacidad de transformar un conjunto de valores y acciones en subjetividad, pero que no logró regular la heterogeneidad de experiencias de las diferentes Facultades que conforma(ba)n la Universidad a partir de impulsar principios capaces de guiar las actividades, de crear vocación y de constituir un sujeto universitario homogéneo.El Estatuto es un texto sobrio, que en su afán de posibilitar la autonomía de las diversas casas de estudio que formaban la Universidad, puede ser caracterizado, a falta de un adjetivo positivo, como no reglamentarista, pero leerlo bajo la lupa de su proceso de sanción da cuenta de la forma en que su austeridad textual condensa un minucioso tratado sobre la forma en que una universidad puede pensar su misión y función social ?conceptos (?misión? y ?función?) de diferentes universos temporales y vocabulares pero presentes de manera indistinta durante todo el ciclo 1955-1960-, pero también, la imposibilidad de legislar sobre la diversidad irreconciliable de las culturas disciplinares, los mecanismos normativos de selección docente, los métodos de enseñanza y la relación entre investigación y formación, de las diez facultades que conformaban la Universidad durante el ciclo histórico. Algunos asambleístas definieron esa imposibilidad como una dificultad existente e insoslayable desde la cual pensar el Estatuto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243181,"idioma_id":4,"titulo":"Forest conservation: Remember Gran Chaco","resumen":"No corresponde","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243185,"idioma_id":4,"titulo":"New records of the endangered Chacoan peccary Catagonus wagneri suggest a broader distribution than currently known","resumen":"The Chacoan peccary Catagonus wagneri is the rarest and most threatened of the three extant species of peccary. Its presence has been recorded in the northern Dry Chaco ecoregion, which spans northern Argentina, western Paraguay and south-eastern Bolivia. However, distribution models based on its occurrence in Argentina have predicted that suitable habitat extends southwards into central Argentina, where the species was not previously recorded. We present several records of the species outside the currently accepted distribution, including the first two records in the west of Córdoba province, > 650 km south of the southern limit of the previously known distribution. The discovery of the Chacoan peccary in central Argentina could serve as a justification for the protection of Chacoan forests in this region, where deforestation rates are among the highest worldwide.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243186,"idioma_id":5,"titulo":"Lista de aves de la Sierra de Guasayán, Santiago del Estero, Argentina","resumen":"La Sierra de Guasayán es una Reserva de Uso Múltiple de la provincia de Santiago del Estero, y un Área Importante para la Conservación de las Aves de la Argentina. No obstante, las investigaciones sobre su avifauna son escasas, reduciéndose principalmente a registros relevantes de algunas especies. Con este estudio, se presenta la primera lista completa de aves de la Sierra de Guasayán, con información novedosa de las abundancias relativas de las especies por tipo de hábitat y épocas reproductiva y no reproductiva, así como una actualización de las especies amenazas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243187,"idioma_id":4,"titulo":"Integration of morphological, ecological, and genetic evidence suggests that the genus Andinomys (Rodentia, Cricetidae) is monospecific","resumen":"Two subspecies of Andinomys edax are currently recognized. Andinomys e. edax ranges from southern Perú to northernmost northwestern Argentina and A. e. lineicaudatus is mainly distributed in southern northwestern Argentina. However, some workers have recognized both taxa as distinct species, stating that A. edax is restricted to Puna and Prepuna habitats between 2,000 and 4,800 m elevation, whereas A. lineicaudatus occurs in Yungas forest below 2,500 m. We assessed the taxonomic status of both forms through an integrative approach including morphological (discrete skin and skull characters), morphometric (univariate and multivariate), geographic environmental niche modeling (Mahalanobis Typicalities), and molecular (Bayesian analysis of cytochrome-b gene sequences) analyses. We did not find characters that consistently differentiated skins and skulls of the 2 forms. The morphometric analysis indicated that lineicaudatus is, on average, larger than edax for some measurements, but only 2 (alveolar width and occipital condyle width) differed significantly between forms. No group of specimens was clearly segregated in the PCA morphospace. Distribution models obtained separately for each taxon do not offer a better fit to the known distribution than models based on the combined data sets. We documented coincident environmental variables as relevant in the model building of edax and lineicaudatus, noting some segregation in elevation, but similar habitat suitability for the remainder of the environmental variables. The geographic continuity between niche models of edax and lineicaudatus was clear but specimens morphologically assignable to each of the nominal forms were not found in areas of overlap. The phylogenetic analyses recovered a polytomy of 4 allopatric and genetically divergent clades, which also failed to support the taxonomic hypothesis of 2 species. Based on all available evidence, we conclude that Andinomys consists of a single species. Nevertheless, observed genetic divergences among clades and their geographic distribution indicate that past events probably fragmented populations of A. edax.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243188,"idioma_id":4,"titulo":"An insecticide formulation of terpene ketones against Sitophilus zeamais and its incorporation into low density polyethylene films","resumen":"The use of active natural compounds derived from plants appears as an interesting alternative for pest control in stored products. In this study, the fumigant toxicity of several terpene ketones against maize weevil (Sitophilus zeamais) adults was assessed, and the effect of their combination with piperonyl butoxide (PBO), a cytochrome P450 inhibitor commonly used as synergistic agent, was investigated. A mixture of the most active ketones (R-(+)-pulegone and thymoquinone) was then tested on S. zeamais, and finally this mixture was incorporated into low density polyethylene (LDPE) films by supercritical CO2 impregnation, in order to study the fumigant toxicity of this formulation against S. zeamais under laboratory conditions, as well as the release profile of the active ketones. PBO showed antagonistic effects in combination with terpene ketones, decreasing the toxicity of the individual compounds and therefore increasing their lethal concentrations. The mixture of ketones showed a lower lethal concentration (LC50 value of 7.12 &#956;L\/L air) than the individual compounds, thus indicating a synergistic effect between them. Finally, the impregnated films revealed high toxicity values (up to 95% mortality), and maintained a moderate level of activity even after 8 days of exposure. In conclusion, the mixture of these active terpene ketones incorporated into a polyethylene film, material commonly used for hermetic storage of maize grains, could be applied as a potential technology against insect pests.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243189,"idioma_id":4,"titulo":"Supercritical CO 2 -assisted impregnation of LDPE\/sepiolite nanocomposite films with insecticidal terpene ketones: impregnation yield, crystallinity and mechanical properties assessment","resumen":"In this contribution, supercritical CO2-assisted impregnation of LDPE\/sepiolite nanocomposite films with two insecticidal terpene ketones (thymoquinone and R-(+)-pulegone) is investigated, as a strategy to enhance the loading capacity compared to pure LDPE. A factorial experimental design was applied in order to evaluate the effect of five process variables at two levels (sepiolite content: 1-10% w\/w; initial ketone mole fraction: 0.0017-0.0025; pressure: 9-13 MPa; depressurization rate: 0.5-2.0 MPa\/min; time: 2-4 h) on impregnation yield, at 45°C. ANOVA test of the results indicated that pressure, time and ketone mole fraction significantly affect impregnation yield (ranging between 2.36 ± 0.18 and 8.60 ± 1.66% w\/w). Thermal analysis (DSC) and X-ray diffraction (XRD) allowed to investigate the nanocomposite morphology and the modifications induced by the impregnation. The mechanical properties of the films were assessed by stress-strain tests, showing that the impregnation process had a very low impact on the material ductility and strength.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243191,"idioma_id":4,"titulo":"Mass transfer kinetics and diffusion coefficient estimation of bioinsecticide terpene ketones in LDPE films obtained by supercritical CO 2 -assisted impregnation","resumen":"Release kinetics of thymoquinone and R-(+)-pulegone impregnated in low-density polyethylene (LDPE) films into air and the effect of supercritical CO2-assisted impregnation process on the diffusional properties of these films were investigated. The incorporation of both ketones into LDPE films was performed under different conditions (pressure, depressurization rate, time, and initial ketone mole fraction). Release experiments were performed under controlled laboratory conditions (24°C, 60% relative humidity), and the total release profile was determined gravimetrically, while the individual release of each ketone was quantified by Fourier transformed infrared. The experimental data were used to fit a mass transfer model based on the second Fick´s law for unsteady-state diffusion, and the diffusion coefficients of both ketones in LDPE were estimated, ranging from 2.35 × 10-13 to 5.53 × 10-13 m2 s-1 (thymoquinone) and from 1.24 × 10-13 to 4.52 × 10-13 m2 s-1 (pulegone). Finally, analysis of variance testing indicated that impregnation pressure and depressurization rate (and their combination) have significant effects on the diffusion coefficient values.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243193,"idioma_id":5,"titulo":"BUSCANDO NUEVOS AROMAS Y SABORES:  ELABORACIÓN DE CERVEZA RUBIA ALE CON EL AGREGADO DE PASAS DE UVA","resumen":"Se elaboró una cerveza rubia tipo alé, utilizando pasas de uva. Se logró modificar el perfil sensorial, dando nuevas notas afrutadas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243194,"idioma_id":4,"titulo":"Existence and uniqueness results for linear second-order equations in the Heisenberg group","resumen":"In this manuscript, we prove uniqueness and existence results of viscosity solutions for a class of linear second-order equations in the Heisenberg group. We state uniqueness by proving a comparison result to our class of equations, and existence via an application of Perron?s method adapted to our framework. We also provide the explicit construction of the appropriate sub- and supersolutions employed by Perron?s method for a variety of domains in the Heisenberg group.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243195,"idioma_id":5,"titulo":"SUSTENTABILIDAD ALIMENTARIA PARTE I","resumen":"Dentro de los Proyectos de Extensión Mauricio López abarca problematicas como alimentacion´, alimentos seguros, salud, ambiente en comunidades vulnerables","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243197,"idioma_id":5,"titulo":"SUSTENTABILIDAD ALIMENTARIA PARTE II","resumen":"Dentro de los Poyectos Mauricio López la segunda parte del artículo trata temas ambientales, salud, sociales y derechos","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243201,"idioma_id":5,"titulo":"Hydrological droughts in Argentina and its relationship with macroclimatic indicators.","resumen":"In this paper, multiannual periodicities in the historical time-series average annual streamflows discharges of 14 rivers of Argentina and in ten macroclimatic indicators are identified using spectral analysis. The estimation of dominant frequencies of the analyzed time series allows to understand the time scale of the processes involved in the hydrological cycles. The spectral analysis found that high, low and medium frequency fluctuations contribute, in different percentages, to the flow variability. Then, this results have been compared with results of similar analysis performed on time series of macro-climatic indicators to calculate the relation of the evolution of these indicators with streamflows discharge series. These results constitute an important step toward implementing conceptual and forecasting models of deficit and excess of surface water in fluvial system for planning and management of the water resources.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243203,"idioma_id":5,"titulo":"ANALYSIS AND HYDRAULIC MODEL (2D) HYPERCONCENTRATED SEDIMENT FLOWS IN WEST OF THE SAWS AMBATO, CATAMARCA, ARGENTINA","resumen":"Hyperconcentrated sediment flows have been classifieldas mudfloods, mudflows and debris flows. Distinct physical processesdifferentiate these types of hyperconcentrations based on the rheology of thewater-sediment mixture. Mudflows are flows with predominant yield and viscousstresses. A quadratic rheological model enables appropiate simulation offlooding conditions ranging from clear water to hyperconcentrated sedimentflows.This paper presents a severehydrological event recently occurred in Siján, Catamarca, Argentina. In thisevent mud flow was generated. This paper present a simulation model of finitedifferences (FLO-2D) to simulate the event.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243204,"idioma_id":4,"titulo":"Rectification of Image Velocity Results (RIVeR): a simple and user-friendly toolbox for large scale water surface Particle Image Velocimetry (PIV) and Particle Tracking Velocimetry (PTV)","resumen":"LSPIV (LargeScale Particle Image Velocimetry) and LSPTV (LargeScale Particle Tracking Velocimetry) are used as relatively low-costand non-intrusive techniques for water -surfacevelocity analysis and flow discharge measurements in rivers or large -scalehydraulic models. This paper describes a methodology based onstate-of-the-art tools (for example,that apply classical PIV\/PTV analysis) resultingin large-scale surface -flowcharacterization, according tothe first operational version of the RIVeR (Rectification of Image VelocityResults). RIVeR is developed in Matlab and is designedto be user -friendly. ItRIVeRprocesses large -scale water -surfacecharacterization such as velocityfields or individual trajectories of floating tracers. Thiswork describes the wide range of application of the techniques forcomparing measured surface flows in hydraulic physical models to flowdischarge estimates for a wide range offlow events in rivers (forexample, low and high flows). ","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243207,"idioma_id":4,"titulo":"Spatio-temporal changes in water quality in an eutrophic lake with artificial aeration","resumen":"In this work we present novel results concerning water quality changes in an eutrophic water body connected with an artificial aeration system insalled in it. Sixty one in-situ and laboratory measurements of biogeochemical variables were recorded monthly between October 2008 and June 2011 to evaluate temporal and spatial changes in San Roque reservoir (Argentina). t-Student mean difference tests, carried out over the whole period, showed with 95% confidence that a monitoring point located at the centre of the water body is representative of the chemical behaviour of the reservoir. Thermal stratification was observed in all sampling sites in the summer, but the frequency of these episodes was markedly lower in bubbling zones. Mean chlorophyll-a concentrations were 58.9 &mu;g&middot;dm-3 and 117.0 &mu;g&middot;dm-3 in the absence and in the presence of thermocline respectively. According to the t-Student test, this difference was significant, with p &lt; 0.001. Phosphate release from sediments was corroborated under hypoxia conditions. ANOVA one way analysis did not show significant spatial differences for any variable. Mean normalize spatial index (MENSI) was developed to compare data from different regions affected by high temporal variability. It proved to be useful to quantify spatial differences. Structure analysis of temporal series was used to scrutinize both chemical and spatial association successfully. Three chemically different zones were determined in the reservoir. This study demonstrated that spatial comparisons by means of marginal statistics may not be an adequate method when high temporal variation is present. In such a case, temporal structure analysis has to be considered.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243212,"idioma_id":5,"titulo":"RAICES ROMANISTAS DEL CODIGO CIVIL Y COMERCIAL ARGENTINO","resumen":"Los autores analizan el Nuevo Código Civil y Comercial Argentino y las influencias, recepciones y divergencias con las correspondientes instituciones jurídicas del Derecho Romano.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243215,"idioma_id":4,"titulo":"Light and dark rations and the photic entrainment of circadian locomotor activity patterns in the South American Silver Catfish ( Rhamdia quelen, Quoy &amp; Gaimard, 1824)","resumen":"The aim of this study was to evaluate the daily rhythm of locomotor activity in Rhamdia quelen (R. quelen). A total of 30 fish were enrolled in the study and were equally divided in 10 groups and maintained in 100 liters tanks. The locomotor activity was measured in fish maintained under the LD 12:12 photoperiod regime; thereafter, the LD cycle was reversed to DL in order to study the resynchronization and to explore the endogenous pacemaker. Subsequently, the fish were subjected to constant conditions of light to test whether or not locomotor rhythms are regulated by the endogenous circadian clock. The effect of increasing light length and intensity was studied on daily rhythm of locomotor activity of fish. Our results showed that the R. quelen is a strictly diurnal species, the rhythm of locomotory activity resynchronized quickly after inverting the LD cycle and persist under free course LL, suggesting a circadian origin. The light showed a significant masking effect often blocking the expression of the biological rhythm. The strictly diurnal behavior is controlled directly by the photoperiod and maintained even under very dim light (30 lux).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243217,"idioma_id":4,"titulo":"Daily rhythmicity of behavior of nine species of South American feral felids in captivity","resumen":"The authors analyzed the daily activity rhythms of the domestic cat and of eight of the ten feral felid species thatare indigenous to South America. All species showed daily rhythmicity of activity in captivity under a naturallight-dark cycle. The robustness of the rhythmicity varied from species to species, but the grand mean of 34%was within the range of robustness previously described for mammalian species ranging in size from mice tocattle. There was not a sharp division between diurnal and nocturnal felids. Instead, what was found was agradient of diurnality going from the predominantly nocturnal margay (72% of activity counts during the night)to the predominantly diurnal jaguarundi (87% of activity counts during the day) with the remaining specieslying in between these two extremes. The ecological implications of temporal niche variations are discussed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243218,"idioma_id":5,"titulo":"Prevalencia de bacterias enteropatógenas en niños que asisten a un hospital pediátrico en Resistencia, Chaco, Argentina","resumen":"La enfermedad diarreica aguda continúa siendo uno de los problemas de salud pública más serios en los países en desarrollo, en los que constituye una de las causas principales de enfermedad y muerte en los niños menores de 5 años. Su epidemiología es totalmente dependiente de la región geográfica, nivel socio económico, costumbres y hábitos de la población.El objetivo del presente trabajo fue determinar la prevalencia de agentes etiológicos bacterianos causantes de diarrea aguda, en niños atendidos en un Hospital Pediátrico de Resistencia, Chaco, en el año 2013.Se investigó la presencia de Shigella spp., Salmonella spp., Campylobacte rspp., Escherichia coli O157:H7 en muestras de materia fecal de niños con enfermedad diarreica aguda.Sobre 823 muestras de materia fecal analizadas en el período mencionado, 93 resultaron positivas para alguno de los enteropatógenos estudiados (Tasa de recuperación del 11,3%).Las frecuencias de aislamiento de los enteropatógenos fueron: Shigella spp (82,8%), Salmonella spp (9,7%), Campylobacter spp (6,5%), y E. coli O157:H7 (1%).Con respecto a las especies, dentro del género Shigella predominó S. flexneri (60\/77) seguida de S. sonnei (13\/77) y S. boydii (4\/77). Con excepción de E. coli O157, en el presente trabajo no se estudiaron los diferentes tipos patogénicos.Como en el resto del país, S. flexneri continúa siendo el agente etiológico más frecuentemente aislado. Este es el primer informe sobre la presencia de Campylobacter en coprocultivos en la provincia del Chaco.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243223,"idioma_id":5,"titulo":"El  nombre del universo: primeros apuntes sobre el Cuaderno de Teología de Mario Bellatin","resumen":"Entre la cada vez más vasta producción literaria de Mario Bellatin se encuentra un cuaderno de apuntes de la época en que estudió Literatura en la Universidad de San Marcos y fue seminarista en Santo Toribio de Mogrovejo. Este Cuaderno de Teología, con el cual Bellatin registró clases de teología pero también de filosofía, tenía como objetivo el de servir como material de escritura. El siguiente trabajo intenta dar cuenta de los problemas archivísticos y teóricos que presenta un documento cuya singularidad consiste en que, a diferencia de los ?cuadernos literarios?, rehúye en stricto sensu la preparación de textos, relatos y que, en cambio, sostenemos que estaría destinado a la preparación de la Obra o, por lo menos, la de sus condiciones de posibilidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243224,"idioma_id":5,"titulo":"El cuerpo humano a debate: reflexiones jurídicas","resumen":"Por la conjunción de las biotecnologías, la ingeniería genética, la nanorobótica y las neurociencias, en alianza con las ciencias y tecnologías de la información, el cuerpo humano aparece atravesado por nuevos y complejos problemas éticos y jurídicos. Se asume una mentalidad que considera al cuerpo como ?material disponible? para ser transformada e incluso reemplazada a voluntad. En este trabajo procuramos presentar una descripción de algunas de las posibilidades biotecnológicas que intervienen sobre el cuerpo o sus partes. Luego realizamos una referencia a los principios jurídicos implicados en estas temáticas vinculadas con el cuerpo humano. Nos referimos sobre todo a la dignidad humana y sus proyecciones sobre la dimensión corporal de la persona. Finalmente, se consideran algunas posibles respuestas jurídicas a las cuestiones planteadas inicialmente, con particular relación a la situación del ordenamiento jurídico argentino.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243225,"idioma_id":5,"titulo":"La capacidad de ejercicio en el nuevo Código Civil y Comercial: entre la autonomía y la protección","resumen":"La derogación del Código Civil de Vélez Sarsfield (ley 340 y sus modificatorias) y la entrada en vigencia del nuevo Código Civil y Comercial (ley 26.994, en adelante CCC) constituyen un hito para el derecho civil que signa la vida jurídica argentina. Entre muchos temas afectados por el nuevo código, nos proponemos estudiar la problemática de las modificaciones operadas en torno a la capacidad de ejercicio de la persona humana.La hipótesis de trabajo es que se verifica una tensión entre la autonomía y la protección en relación a la capacidad de ejercicio. Nos proponemos analizar cómo se presenta esa tensión en las normas del Código Civil y Comercial.Nuestro estudio se concentrará, sobre todo, en la regulación civil de la capacidad de las personas menores de edad y las personas con padecimientos mentales.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243226,"idioma_id":5,"titulo":"La personalización de los apoyos para el ejercicio de la capacidad","resumen":"Comentario a una sentencia sobre determinación de la capacidad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243227,"idioma_id":5,"titulo":"¿Los seres humanos somos meros algoritmos? Una reflexión crítica sobre el libro Homo Deus","resumen":"Análisis del libro Homo Deus.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243228,"idioma_id":5,"titulo":"Amoris Laetitia: una vuelta de rosca a la teologia moral?","resumen":"En 2016, Alemania, un grupo de teólogos publican por la editorial Herder sus reflexiones sobre la perspectiva que, de la teología moral, tiene el Papa Francisco, bajo el título de Amoris Laetitia - Wendepunkt fur die Moraltheologie?, editado por Stephan Goertz y Caroline Witting. La repercusión del mismo en el ámbito de la teología moral llevó a que se tradujera y publicara en Italia al año siguiente , a la cura de Antonio Autiero, bajo el título de: Amoris Laetitia: Un punto di svolta per la teologia morale? por editorial Paulinas. Sin lugar a dudas, las reflexiones de estos alemanes han despertado curiosidad en más de un contexto teológico. Esto último hace pertinente publicar, aunque más no sea unas líneas, sobre los textos publicados en ese libro, con el fin de abrir nuevas perspectivas al debate sobre moral en el contexto latinoamericano, lugar de origen del actual pontífice.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243230,"idioma_id":5,"titulo":"Trabajo y dignidad humana: un impulso ético-teológico del Papa Francisco","resumen":"El trabajo es uno de los temas centrales en el discurso del Papa Francisco. Se presentan los fundamentos mínimos que justifican ese discurso como teológico, con la intención de despejar dudas que ponen en cuestión una pastoral con esas características. La dignidad del hombre trabajador es uno de ellos. El argumento se construye a partir de las Sagradas Escrituras, en concordancia con el magisterio episcopal latinoamericano y el magisterio pontificio, estableciendo un diálogo con la estética, la sociología y la ciencia política. Las afirmaciones del actual papa argentino requieren una breve descripción de las condiciones del trabajo, y de la organización de los trabajadores, en su país y su continente, América Latina, para que su palabra pueda entenderse de manera situada. A tal efecto se presenta el modelo de las organizaciones de los trabajadores en ese contexto, empleados y desempleados, es decir el sindicalismo y los movimientos populares, respectivamente. Se trabaja con documentos magisteriales como Aparecida, Evangelii Gaudium y Laudato Si, y con discursos pontificios. Se describe la tensión entre Estado y sindicalismo en la región, y el surgimientos de los movimientos populares impulsados por el Papa Francisco ante la crisis de representatividad de los partidos políticos como nueva vía para garantizar los derechos de los trabajadores.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243233,"idioma_id":5,"titulo":"El cuidado en personas en situación de calle. Una perspectiva ética y política.","resumen":"En la políticasocio-asistencial con personas en situaciónde calle (PSC), en la Ciudad de Buenos Aires, se involucranrepresentaciones sociales de los operadores socialessobre estas personas. Ellos las consideran irresponsables,?vagas? y con inadecuación del yo. La labilidadafectiva en los vínculossociales transitorios los transformanen objetos pasivos de cuidado. En el marco de unainvestigación-acción sobre trayectorias de PSC se presenta,desde la perspectiva de los protagonistas, la consideraciónde las intervenciones de las prácticas de cuidadoque transcurren en la situación de calle. Se abordaráel fenómeno del cuidado desde su perspectiva ética política.Resultados indican la existencia de tensión entre intervencionessostenidas desde el déficit, desde las quelas PSC constituyen ?objetos de cuidado? y otras prácticassostenidas en la construcción de autonomía y en el reconocimientode la PSC como ?sujeto que cuida?.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243235,"idioma_id":5,"titulo":"Circuitos socio-asistenciales para Población en Situación de Calle en la Ciudad de Buenos Aires: entre la Autonomía y la Dependencia","resumen":"El presente trabajo se enmarca en un proyecto de investigación participativa financiado por la Universidad de Buenos Aires, que tiene como objetivo indagar las trayectorias de vida y los procesos de construcción de identidad en personas en situación de calle (PSC) en la Ciudad de Buenos Aires (Argentina), y generar un espacio de participación y reflexión colectiva que facilite problematizar dichas trayectorias así como los circuitos socio-asistenciales por los que transitan. Con una modalidad de investigación cualitativa de tipo participativa, el trabajo se organizó en tres etapas: (a) diagnóstico participativo, (b) mapeo colectivo y (c) primera intervención. Con un muestreo intencional, se conformó una muestra de organizaciones que son parte de la oferta asistencial y con un muestreo bola de nieve de personas adultas, hombres y mujeres, que se encuentran en situación de calle, con una permanencia mayor a tres años. A partir de los resultados se pretende problematizar los límites y desafíos de las intervenciones con enfoques comunitarios con personas en situación de calle, así como también las relaciones entre la Universidad y la Comunidad en los procesos de construcción de conocimientos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243236,"idioma_id":5,"titulo":"Dieta popular: papa y pancho\/El Vaticano entre la modernizacion y la reforma","resumen":"Conferencia desgrabada","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243237,"idioma_id":5,"titulo":"El Endeudamiento de la etica teologica aplicada","resumen":"El espacio teológico no escapa a la lógica de los tiempos modernos, donde todo capital -ya sea financiero, social o cultural- se acumula sobre el endeudamiento del prójimo. La lógica del endeudamiento es señalar la falta en el otro. Hacer visible al otro que algo le hace falta para justificar su exclusión del mundo simbólico, que es la cultura y está conformado por  instituciones laborales, familiares, políticas y también académicas. La falta puede ser dinero, pero también conocimiento canónico -es decir, el reconocido como válido. El muro es interno a la cultura, el peaje es un cierto capital acumulado, y la causa de la condena es la falta de ese capital canónico. Si no se tiene algo acumulado no se pasará.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243238,"idioma_id":5,"titulo":"El Endeudamiento de la etica teologica aplicada","resumen":"El espacio teológico no escapa a la lógica de los tiempos modernos, donde todo capital -ya sea financiero, social o cultural- se acumula sobre el endeudamiento del prójimo. La lógica del endeudamiento es señalar la falta en el otro. Hacer visible al otro que algo le hace falta para justificar su exclusión del mundo simbólico, que es la cultura y está conformado por  instituciones laborales, familiares, políticas y también académicas. La falta puede ser dinero, pero también conocimiento canónico -es decir, el reconocido como válido. El muro es interno a la cultura, el peaje es un cierto capital acumulado, y la causa de la condena es la falta de ese capital canónico. Si no se tiene algo acumulado no se pasará.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243239,"idioma_id":4,"titulo":"Pope Francis?s Politics","resumen":"Editora. IntroducionLa importancia de la voz del Papa Francisco en el escenario político internacional es un tema que no admite discusión. Algunos lo critican por su posición frente al sistema, y otros lo siguen aun sin ser católicos. Un Papa que no pasa desapercibido y despierta pasiones. Nadie hubiese pensado que, a estas alturas de una cultura liberal secular, un pontífice católico fuera el hombre político del momento. Esto puede tener muchas lecturas. Por un lado, puede pensarse que el liberalismo politico y economico esta llegando a su fin y como muestra de ello se visibiliza una nueva era postsecular donde un pontífice pasa a ser la voz política más autorizada. Por otro lado, puede pensarse que es una nueva versión del socialismo decimonónico y que no pasara de ser una buena utopia.Sin embargo, el Papa cabalga. No hay jefe de Estado que no necesite de una foto con Francisco para sellar su legitimidad. No hay academia en el mundo que no haya organizado un seminario científico de discusión sobre lo que dice el Papa. No hay periódico serio ni revista de divulgación que no lo tenga en alguna de sus tapas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243240,"idioma_id":5,"titulo":"Francisco y la teologia de la cultura: discernimiento violencia-misericordia","resumen":"El discurso pastoral del Papa Francisco representa una teología de la cultura situada que llama a discernir sobre violencia-misericordia. El Papa denuncia los resultados del sistema y ataca sus causas. Comprenderlo implica una reflexión académica interdisciplinar  sobre las características de la cultura actual que actúan como condición del discernimiento. Reflexionando de manera situada, se observan cambios tecnológicos significativos en los medios de comunicación que generan transformaciones en la cultura de un Estado moderno que aún continua pero que, en el siglo XXI, da signos de un giro  postsecular donde lo político requiere nuevamente de lo teológico, no ya como fundamento sino como pensamiento crítico que tienda a desacralizar dioses mortales. Se presentarán, en un intento de diálogo interdisciplinario, los puntos de vista de cuatro autores: Antonio Spadaro SJ y su noción de cultura ciberespacial desterritorializada; Giacomo Marramao y su noción de postsecularismo y constitución de identidad; Miguel Yañez SJ y su interpretación de pobreza  como violencia; y Luis Sarasa SJ su lectura bíblica de la  reconciliación en la tensión del conflicto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243241,"idioma_id":5,"titulo":"Comparación de dos alternativas de invernada intensiva con biotipos británicos","resumen":"En un marco de intensificación de la ganadería en la región pampeana, el uso de encierres a corral combinados con etapas pastoriles surge como una alternativa promisoria para lograr sistemas intensivos eficientes. El objetivo del presente trabajo fue comparar la productividad y resultados económicos, de tres ciclos anuales consecutivos (2013\/14, 2014\/15 y 2015\/16), de un sistema pastoril intensivo convencional con un sistema experimental de invernada base pastoril de doble ingreso anual con terminación a corral. La experiencia se realizó en la EEA INTA Marcos Juárez sobre un suelo argiudol típico, sin limitaciones de uso, sujeto a una rotación de 50% de pasturas base alfalfa y el resto de cultivos agrícolas. Los sistemas experimentales fueron uno de ingreso único otoñal de machos británicos a la pastura y el segundo de doble ingreso (otoñal y primaveral) con posterior terminación a corral de cada uno. Durante la etapa pastoril ambos sistemas fueron suplementados con grano de maíz quebrado al 0,5-0,6% PV y heno de alfalfa, mientras que la terminación del segundo sistema tuvo una dieta típica de grano de maíz y heno de alfalfa a voluntad. Ambos sistemas tuvieron similar producción forrajera anual, siendo 23.868 y 23.403 kg MS\/ha para el sistema de ingreso único y doble, respectivamente. La carga por superficie ganadera ajustada que permitió sostener el sistema con terminación a corral fue 57% superior (1.755 vs. 1.117 kg PV\/HG), mientras que la productividad sólo fue 33% mayor (1.098 vs. 824 kg\/HG) debido al menor peso de venta (359,1 vs. 392,1 kg). Dentro del sistema de ingreso doble, el ciclo de ingreso otoñal tuvo mejor desempeño logrando un aumento medio diario total de 825 g\/día, superior a los 610 g\/día del ciclo de ingreso primaveral. El margen bruto (MB) por ha del sistema de ingreso doble fue superior al convencional ($17.184 vs. $13.727), aunque con una peor relación MB\/costos directos (0,15 vs. 0,27). Se concluye que ambos sistemas lograron alta productividad y MB competitivos, y que el sistema de doble ingreso con terminación a corral es una alternativa viable de intensificación pero con mayor nivel de riesgo económico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243242,"idioma_id":5,"titulo":"La centralidad del trabajo en el pontificado de Francisco","resumen":"¿Es lícito que la teología se ocupe del trabajo? El discurso teológico debe distinguirse del discurso religioso, del ético y del político. Del religioso por dos motivos, por un lado corre el riesgo de relativizar a la altura de un discurso políticamente correcto para ser aceptado por un mundo secularizado, por otro lado por correr el riesgo de ser desplazado al plano de lo privado como mera práctica ritualista invalidando cualquier expresión social; del ético, porque corre el riesgo de quedarse en el plano de juzgar efectos sin cuestionar sus causas; del político porque termina reivindicando el discurso de personas particulares si este coincide con los principios cristianos, pero despojado -para ser tolerado en un contexto liberal-, de todo carácter teológico, es decir salvífico\/escatológico. La teología, en el campo de una economía de la salvación, se ocupa de la creación, es decir de la obra de Dios, que es el mundo y el hombre. En consecuencia es lícito que se ocupe de las causas que originan un modelo cultural que, luego de ser sacralizadas, legitiman un sistema social injusto. En la teología, a diferencia de la filosofía o la política, los principios son revelados de una vez y para siempre. A partir de esos principios de fe cada generación reflexiona, de manera situada, si las condiciones culturales son suficientes para que todos los hombres creados por Dios vivan de acuerdo a su dignidad de  libres e iguales. Esa reflexión es la de un pueblo -ochlos\/pobre-, que a partir del agonismo deviene laos\/sujeto de la historia consciente de serlo, y se constituye por ese acto de consciencia en Iglesia, Pueblo de Dios, no como momento político del conflicto sino como asamblea permanente que camina en la historia defendiendo el origen divino del hombre, creado a imagen y semejanza de Dios, con una dignidad conseguida por Jesús el Cristo quien con su muerte y resurrección venció al enemigo y consiguió para todos la victoria. Ese principio revelado es el fundamento desde el cual la teología cristiana mira, juzga y actúa en el mundo, en diálogo con  las religiones, la ética y la política, para que el pueblo-pobre-trabajador tenga vida, y la tenga en abundancia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243243,"idioma_id":4,"titulo":"Pope Francis: It is the Politics!","resumen":"This article will try to establish a relationship between economy and religion based onthe speech of the new Latin American Pontiff, Pope Francis, for whom the problem ofglobal crisis should not be sought in the economy but in politics. The pontiff believesthat the economy should be subordinated to the politics and not the other way around.Trying to find a solution to the global political and economic crisis involvesinvestigating the theological causes that sustain structural poverty. Francisco, as a newprophet in times of capitalism, relying on the documents of the Latin Americanarchbishops, denounces that the lack of work that originates this system originates aculture of death. Political theology can unmask false gods that support this system, andproclaim the importance of a poor working people who must be treated with dignity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243244,"idioma_id":5,"titulo":"El nuevo libro de Antonio Spadaro sobre el papa Francisco: una obra intervenida","resumen":"?Creatividad? es la clave para entender la lectura que Antonio Spadaro S.J. hace del corpuscompleto de homilías, discursos y mensajes de Jorge Mario Bergoglio entre el 2001 y el 2013.Eso explica por qué, en el nuevo libro del Papa Francisco recientemente publicado en Italia, Entus ojos está mi palabra, resulta más interesante el prólogo donde Spadaro lo entrevista, que losdocumentos del ex-cardenal Bergoglio. La obra no es, ni una biografía, ni una selección temáticade fragmentos. Los documentos se presentan cronológicamente porque el curador no quierepecar de funcionalismo seleccionando textos que justifiquen una lectura ideológica de lapalabra de Bergoglio. Sin embargo, con su prologo e introducción condiciona la lectura. AntonioSpadaro, teólogo jesuita y comunicador social, es un especialista en estética que juega con haceruna intervención sobre las homilías, y con eso capta plenamente el espíritu de la Teología delPueblo. Quiere hacer visible las imágenes [del pueblo pobre y trabajador argentino] quepermanecen impresas en sus pupilas [las del Papa Francisco] y que han provocado una respuestaverbal, es decir una homilía, un discurso o un mensaje. Ve las homilías de Bergoglio como unacto de creación que se produce en un momento estético-teológico, el del contacto entre pastor ypueblo. ¿Producía eso Bergoglio?","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243245,"idioma_id":5,"titulo":"Aportes a la colección de hongos liquenizados del herbario del Instituto de Botánica Carlos Spegazzini (LPS)","resumen":"El Instituto de Botánica Carlos Spegazzini (IBCS) (UNLP, La Plata) contiene un herbario dehongos (LPS) de aproximadamente 40000 ejemplares, con 4200 especies tipo. El objetivo de este trabajofue examinar los ejemplares de hongos liquenizados depositados en el IBCS, actualizar su taxonomíay denominación, revisar las especies con determinación dudosa, identificar aquellos no determinados,e incorporarlos en el Herbario LPS. Se estudiaron 192 ejemplares de 11 provincias de Argentina yde Brasil, Uruguay y Francia y de se determinaron en base a su exo-morfología, cortes histológicosy reacciones histoquímicas. También se realizaron Cromatografías en Capa Delgada (TLC) para estudiar los metabolitos presentes. Se estableció la distribución geográfica en Argentina de las especies identificadas. Se corrigió el 91,66% de los materiales examinados (176 ejemplares), contabilizándose un total de 91 especies, 50 géneros y 21 familias, siendo las mejor representadas Parmeliaceae (16 géneros; 31 especies), Graphidaceae (4; 5) y Physciaceae (3; 9). Se actualizó la nominación de 56 ejemplares pertenecientes a 32 especies. Se modificó la identidad de 120 ejemplares, a nivel de especie (87), género (33) y familia (1). Se amplía la distribución en Argentina de 9 especies.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243246,"idioma_id":4,"titulo":"Observations of the development of Xanthoparmelia farinosa under optical and electron microscopy","resumen":"Xanthoparmelia farinosa is a foliose lichen widely distributed in South America, growing not only on rocks but also on man-made structures. This species has abundant soralia, but it is unknown how development occurs from the soredium to the formation of a complete thallus. The soredia were extracted from the thallus with forceps, planted on glass plates and exposed to outdoor conditions for a period of 24 months; in every 3 months, optical inspection was performed with a stereomicroscope and a compound microscope, in addition, four samples with different exposure times were chosen to observe under a scanning electron microscope. The development of hyphae and the adhesion of these to the substrate, and the outlines of the formation of the lobules and rhizines could be observed. Our study is a first attempt to understand the development of this species which is endemic to South America and very common in the area.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243249,"idioma_id":4,"titulo":"Commentary","resumen":"COMMENTARY ON GUILLAIN-BARRÉ AND TUBERCULOSIS","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243252,"idioma_id":5,"titulo":"El cambio en la política exterior de EEUU que permitió el desarrollo del uso pacífico de energía nuclear en Argentina","resumen":"Las bombas atómicas arrojadas sobre Japón no significan sólo el fin de la Segunda Guerra Mundial en 1945. También es el punto de partida para el creciente interés de los países periféricos para obtener dicha tecnología, aunque no desde un enfoque bélico sino como oportunidad de desarrollo. El presente trabajo explora el cambio de la política de cooperación estadounidense en referencia a los conocimientos sobre la energía nuclear y cómo fue la relación de Argentina con Estados Unidos durante su propio proceso de desarrollo nuclear, hasta la concreción del primer reactor RA-1.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243259,"idioma_id":4,"titulo":"Effects of percutaneous microelectrolysis (MEP®) on pain, rom and morning stiffness in patients with achilles tendinopathy","resumen":"Background: Achilles tendinopathy is the third most common disease in the musculoskeletal system. Most frequent symptoms include exercise induced pain and edema. Physical therapy has an important role in symptoms reduction, progression decrease and recovering function. In the last years new technologies have been proposed to treat tendinopathies, such us Percutaneous Microelectrolysis (MEP). This technique employs a galvanic current up to 990 uA, which is applied percutaneously with an acupuncture needle connected to the cathode, to promote a controlled inflammatory response and free radical inhibition.Purpose: The aim of this study was to evaluate the effects of MEP on pain, range of motion (ROM) and matinal stiffness in patients with Achilles tendinopathy. Methods: This randomized controlled clinical trial was carried out in Clínicas Integradas da Universidade Potiguar.Twenty patients with Achilles tendinopathy that accepted to participate in this research wererandomly divided into two groups.Control Group (G1): 1- Warm up with a stationary bike for 10 minutes; 2- Stretching adductors, abductors, hamstrings and plantar flexors (3 x 30?), two minutes rest between sets; 3- Friction massage the Achilles tendon; 4- Stretching of the plantar fascia; 5- Eccentric exercises for plantar flexors (3 sets x 15 reps). The treatment was applied twice a week during a month (eight sessions in total).Treatment Group (G2): Same protocol of G1, plus MEP® once a week. MEP® (Fisiomove) was used as follows: 1 - Disinfection of the treatment zone with alcohol. 2 - A 0.22x13 mm needle was introduced three times during each session, at different points in the Achilles tendon with an initial intensity of 100 uA (microamperes). 3 - The intensity was increased up to 450 uA (microamperes).The on time was 20 seconds and the rest time 40 seconds, totaling to 3 minutes.To assess the response to the treatments, some questions related to function and exerciseparticipation included in Visa-A questionnaire, goniometry and Visual Analogue Scale (VAS) were used.Data was analyzed using Paired and Independent T test, with a significance level of 5%.Results: The reduction of pain (VAS) was significant between groups (p &lt; 0.05). A significant difference (p &lt; 0.05) in range of motion (ROM) in the ankle was observed for plantar flexion and eversion between groups. There was a significant improvement (p &lt; 0.05) in the VISA-A questionnaire in the G2.Conclusion(s): Treatment Group with MEP® (G2) showed greater pain reduction, increased ankle ROM and the morning stiffness duration decreased when compared to the G1.Implications: This study showed that MEP® is a promise technique for Achilles&nbsp; tendinopathies. The application of this therapeutic modality could impact favorably in the public health cost due to their simplicity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243261,"idioma_id":4,"titulo":"On the Placement of Hydrogen and Helium in the Periodic System: A Response to Cvetkovic and Petrusevski","resumen":"On the Placement of Hydrogen and Helium in the Periodic System: A Response to Cvetkovi&#263; and Petrusevski","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243263,"idioma_id":4,"titulo":"Influence of altitude and enhanced ultraviolet-B radiation on tuber production, seed viability, leaf pigments and morphology in the wild potato species Solanum kurtzianum Bitter &amp; Wittm collected from an elevational gradient","resumen":"Climate change could lead to an upward shift in plant distribution, exposing populations to higher levels of ultraviolet (UV)-B radiation. In the framework of an in situ strategy for conserving potato wild relatives, we evaluated the effect of high UV-B levels on natural population of Solanum kurtzianum. The hypothesis is that plants from naturally higher altitudes are better acclimated to increased UV-B radiation. Two populations from low and high altitudes were field supplemented using UV-B-lamps (+UV-B) or excluded from it with plastic filters. Additionally, to assess in which extent the plant responses to these artificial experimental conditions are reproducible in natural conditions, three genotypes were cultivated in two mountain experimental gardens (EG) at different elevations. +UV-B treatment induced changes in leaf morphology and increases in phenolic compounds in both populations, indicating plant acclimation, since chlorophylls and reproductive structures were not negatively affected. These results indicate that this environmental factor may not limit the displacement of populations towards sites with higher UV-B levels. Meanwhile, in higher-altitude EG a tubers yield reduction, mainly through a decreased tuber number, and a bigger accumulation of phenolic compounds than in +UV-B treatment were observed, suggesting that UV-B is not the only factor involved in plants acclimation to high altitude environments.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243265,"idioma_id":4,"titulo":"Internal Morphology of Osteoderms of Extinct Armadillos and Its Relationship with Environmental Conditions","resumen":"The most complete and continuous fossil record of armadillos is composed mostly by isolated osteoderms, frequently found in paleontological and archaeological sites that bear continental South American mammals. Their external morphology has been used to define several species. In the last decade, many authors have focused on the internal structure of vertebrate osteoderms using histological and paleohistological studies. These studies allowed identification of useful features in systematic and phylogenetic contexts. In armadillos, osteoderms are constituted by compact bone tissue (primary and secondary osteons, and concentric layers or lamellae) that delimits cavities, which could contain different soft tissues (adipose tissue, hair follicles, bone marrow, and sweat and sebaceous glands). Traditional paleohistological techniques have allowed the recognition of homologous cavities to those found in osteoderms of current species and from comparison deduce which kind of tissue could had occupied them. We have recently utilized 3D reconstructions in osteoderms of extant species of armadillos to analyze the micromorphology, disposition, and the relationship of different cavities and understand them in depth. Here, we present the results of the application of paleohistology and microtomography in osteoderms of representatives of diferent taxa of extinct Dasypodidae (Astegotheriini, Stegotheriini, ?Utaetini,? Euphractini, Eutatini), which allowed us to compare homologous structures based on their three-dimensional reconstruction. The results, added to the previous external morphology studies, have allowed us to define morphological patterns (consistent within each linage). The variation of the volume and extension of cavities associated with different tissues could be strongly associated with changes in the climate and environmental conditions of the species distribution areas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243266,"idioma_id":4,"titulo":"Integument in Antarctic seals: A comparative study and its relation to extreme environments","resumen":"Due to the semiaquatic lifestyle of seals and the extreme climates they inhabit, their integumentary system has aroused the curiosity of several authors for more than a century. The aim of this contribution was to perform an exhaustive histological de- scription of the integument Antarctic seals through different methodological ap- proaches in a comparative framework. The species considered include the iceobligate?Weddell (Leptonychotes weddellii) and leopard (Hydrurga leptonyx) seal?and the icetolerant, and southern elephant seal (Mirounga leonina). In addi- tion, we attempted to link the histological features to their different lifestyles. All three species showed features related to their amphibious lifestyle (i.e., parakeratotic epidermis with abundant melanin granules, dermis with numerous arteriovenous anastomoses and a great amount of elastic fibres). In aquatic mammals, parakeratosis would decrease cellular replacement, the great amount of melanin is related to the high exposure to solar radiation, the presence of arteriovenous anastomoses is related to thermoregulatory mechanisms, and the presence of elastic fibres is due to varia- tions of thickness in the adipose tissue that requires high elasticity of the dermis.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243269,"idioma_id":4,"titulo":"Adaptation and validation of the Spanish version of the MG Composite Scale for Myasthenia Gravis","resumen":"entitled 'Adaptation and validation of the Spanish version of the MG Composite Scale for Myasthenia Gravis' has been successfully submitted online and is presently being given full consideration for publication in Muscle and Nerve manuscript number is MUS-17-0723.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243270,"idioma_id":4,"titulo":"IUNS. 21st International Congress of Nutrition. Buenos Aires, Argentina, October 15-20, 2017: Abstracts","resumen":"71 supl 2:1-1433pag 1158","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243272,"idioma_id":4,"titulo":"Regional differences in presentation and antithrombotic treatment of patients with atrial fibrillation: Baseline characteristics from a clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with atrial fibrillation (IMPACT-AF)","resumen":"Atrial fibrillation (AF) is the most common sustained arrhythmia worldwide. However, there are few contemporary comparative data on AF from middle-income countries.METHODS: Baseline characteristics of the IMPACT-AF trial were analyzed to assess regional differences in presentation and antithrombotic treatment of AF from 5 middle-income countries (Argentina, Brazil, China, India, and Romania) and factors associated with antithrombotic treatment prescription.RESULTS: IMPACT-AF enrolled 2281 patients (69 ± 11 years, 47% women) at 48 sites. Overall, 66% of patients were on anticoagulation at baseline, ranging from 38% in China to 91% in Brazil. The top 3 reasons for not prescribing an anticoagulant were patient preference\/refusal (26%); concomitant antiplatelet therapy (15%); and risks outweighing the benefits, as assessed by the physician (13%). In a multivariable model, the most significant factors associated with prescription of oral anticoagulants were no prior major bleeding (odds ratio [OR] = 4.34; 95% CI = 2.22-8.33), no alcohol abuse (OR = 2.27; 95% CI = 1.12-4.55), and history of rheumatic valvular heart disease (OR = 2.10; 95% CI = 1.36-3.26), with a strong predictive accuracy (c statistic = 0.85), whereas the most significant factors associated with prescription of a combination of oral anticoagulants and antiplatelet drugs were prior coronary revascularization (OR = 5.10; 95% CI = 2.88-9.05), prior myocardial infarction (OR = 2.24; 95% CI = 1.38-3.63), and no alcohol abuse (OR = 2.22; 95% CI = 1.11-4.55), with a good predictive accuracy (c statistic = 0.76).CONCLUSIONS: IMPACT-AF provides contemporary data from 5 middle-income countries regarding antithrombotic treatment of AF. Lack of prior major bleeding and coronary revascularization were the most important factors associated with prescription of oral anticoagulants and their combination with antiplatelet drugs, respectively.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243275,"idioma_id":5,"titulo":"'Integración curricular de la Educación Sexual Integral. Imaginarios y desafíos a más de una década de su promulgación'","resumen":"Las reflexiones y conceptualizaciones que se presentarán, surgen del Proyecto denominado ?De Sexo si se habla. Talleres de Sexualidad y género?. El mismo se enmarca desde mediados del año 2010 en la Universidad Nacional de Quilmes, como proyecto de extensión, aunque también contribuye al desarrollo de líneas de investigación, capacitación docente y cursos de grado en los Profesorados y Licenciatura en Educación de la institución referente. Dichos proyectos se sustentan en la Ley Nacional 26150, Res CDF\/08, que sienta las bases del Programa Nacional de Educación Sexual Integral, con la finalidad de promover su tratamiento en la escuela secundaria como contenido transversal de la propuesta curricular, atendiendo a los derechos sexuales y reproductivos de los adolescentes, desde una perspectiva alternativa a los modelos de tipo biologicista.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243278,"idioma_id":5,"titulo":"Variaciones sobre el deseo. Colonialismo, zona de no ser y plano de inmanencia","resumen":"ResumenVariaciones sobre el deseo Colonialismo, zona de no ser y plano de inmanenciaEl trabajo se concentra en el problema del deseo en la escritura fanoniana y sus proyecciones al espacio de la filosofi&#769;a de Deleuze y Guattari. Sostenemos que la figura del deseo en los escritos fanonianos se transforma poco a poco desde una idea del deseo articulado a partir de la idea de falta hacia un deseo como positividad, el cual se adecua a las condiciones poscoloniales de la imaginacio&#769;n poli&#769;tica y coincide, desde otras marcas anali&#769;ticas, con las formas en que Deleuze- Guattari pensaron el problema del plano de inmanencia. Esto hace que ambos itinerarios intelectuales y sus escrituras se precisen. En ese pasaje ocurren dos procesos cruciales, el primero es la cri&#769;tica de las lo&#769;gicas compensatorias de las categori&#769;as frente al colonialismo y el segundo es la cri&#769;tica de la representacio&#769;n. Al final sugerimos que ambas escrituras logran conjurar estos procesos a partir de producir espacios no normados por la relacio&#769;n modernidad-colonialidad.Palabras clave: Fanon- Deleuze-Guattari-Colonialidad-DeseoAbstractWe focus here on the problem of desire in Fanonian writing and its projections to the space of the Deleuze-Guattari &#769;s philosophy. We hold that the figure of desire in Fanon &#769;s texts is gradually transformed from an idea of desire articulated as lack, to an idea of desire as positivity, which is adapted to the postcolonial conditions of the political imagination and it is side by side with -from different analytical marks-, the ways in which Deleuze-Guattari discuss on of plane of immanence. This makes that Fanon and Deleuze-Guattari intellectual itineraries and their writings, precise each other. In this passage two crucial processes occur, the first is the critique of the compensatory logics of categories facing colonialism, and the second is the critique of representation. Last but not least we suggest and emphasize that both writings overcame these processes and produce spaces not regulated by the modernity-coloniality relationship.Alejandro De Oto Cristina PoslemanKey words: Fanon- Deleuze-Guattari- Coloniality-Desire. Indizada en Philosopher´s index.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243279,"idioma_id":5,"titulo":"Fanon, crítica poscolonial y teoría Notas en contextos latinoamericanos","resumen":"Este artículo es una propuesta para organizar los itinerarios que la escritura de Fanon describió en contextos latinoamericanos durante los últimos cincuenta años. Es una manera posible de establecer la discusión sobre el legado Fanoniano y los diferentes enfoques que ofrece. Al mismo tiempo, este texto intenta vincular las principales preocupaciones de cada época con las formas en que Fanon fue leído y pensar contextualmente en los archivos emergentes. Por lo tanto, se trata de un compromiso por su escritura para que se convierta en una parte activa de los registros actuales de la teoría social, de la filosofía y del campo general de las ciencias sociales y las humanidades.Indizada en Latindex-Directorio, Larindex-Catálogo- DOAJ.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243281,"idioma_id":4,"titulo":"Lunar fingerprints in the modulated incoming solar radiation: In situ insolation and latitudinal insolation gradients as two important interpretative metrics for paleoclimatic data records and theoretical climate modeling","resumen":"Abstract","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243283,"idioma_id":4,"titulo":"Tempo and mode in Trilobite Evolutionary Faunas replacement from the Cordillera Oriental basin (Northwestern Argentina)","resumen":"Major ecological transitions among evolutionary faunas is amatter of continuous debate.Our study analyses the timing and mode of replacement of Ibex I and IITrilobite Evolutionary Faunas (TEF) in Early Ordovician successions ofNorthwestern Argentina, with special emphasis on olenids and asaphids askey groups of the Ibex I and Ibex II faunas, respectively. We explorerichness by using the sample rarefaction method, and occupancy based on apresence-absence dataset. The late Tr2 represents an inflexion point inrichness and occupancy trajectories of asaphids and olenids. Whileolenids diminish their generic richness through time, asaphids became therichest family since the Tr3 predating the global trend recognized forthe expansion of the Ibex II Fauna. Asaphids gained diversity at theexpense of other trilobites, as well, their rise in diversity lags behindthe increase in occupancy suggesting a displacement scenario as theprobable mode of replacement between the Ibex I and II TEFs. Apparently,processes of replacement variate among regions across the globe,configuring a complex global mosaic of regional patterns.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243284,"idioma_id":4,"titulo":"Immune response of Staphylococcus aureus strains in a mouse mastitis model is linked to adaptive capacity and genotypic profiles","resumen":"Staphylococcus aureus is one of the most frequently isolated major pathogens from intramammary infections(IMI) worldwide. The mechanisms by which S. aureus IMI are established and maintained in dairy cows involveboth bacterial escape strategies and modulation of the host immune response. Moreover, it was shown thatdifferent S. aureus strains have varying effects on the immune response. The aim of this study was to investigatethe immune response in a mouse mastitis model of two S. aureus strains isolated from bovine IMI with differentclinical manifestation (persistent-P or non-persistent-NP), phenotypic and genotypic profile. Both strains werecapable of establishing an IMI after 264 h post inoculation (pi). Strain A (NP) showed a more aggressivebehaviour than strain B (P) at early stages of IMI, while strain B multiplied initially at a lower rate but increasedits replication capacity from 120 h pi to the end of the study (264 h pi). Strain A triggered a stronger initialinflammatory response compared with strain B inducing higher gene and protein expression of TLR2, NF-&#954;Bactivation and higher gene expression of IL-1&#945; at initial stage of IMI (6?12 h pi) but inducing extensivemammary tissue damage. Immune cells response was different for each S. aureus strain throughout the course ofinfection, showing mammary glands inoculated with strain A greater initial immune cells stimulation comparedwith strain B and then a second immune cells stimulation (from 120 to 264 h pi) represented by monocytesmacrophages,T and B lymphocytes, mainly stimulated by strain B, consistent with inflammatory processbecoming chronic. Strain-specific pathogenicity observed underscores the importance of pathogen factors in theprogression of the infectious process. These results contribute to increase the available information on hostpathogeninteraction and point out for the need of further research to expand the knowledge about theseinteractions for developing new strategies to intervene in the IMI progress.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243285,"idioma_id":5,"titulo":"Analisis de la consanguinidad de la poblacion de bovinos Holando inscriptos en el sistema de Control Lechero Oficial de la Republica Argentina","resumen":"Valores crecientes de consanguinidad pueden reducir la fertilidad, salud y productividad de los bovinos lecheros.El objetivo fue estimar el coeficiente de consanguinidad de la población de bovinos Holando Argentinocon registro genealógico en la base de datos de la Asociación Criadores de Holando Argentino. La poblaciónen estudio comprendió 422.563 animales con ancestros conocidos, origen argentino y nacidos entre los años1990 y 2009, referente a la genealogía de hembras de Registro de Crías (grado) y Registro de Pedigrí delSistema Nacional de Control Lechero Oficial. Los coeficientes de consanguinidad fueron obtenidos mediantela implementación de un algoritmo recursivo modificado que considera la consanguinidad de padres desconocidos.La consanguinidad promedio para los 422.563 animales fue 3,38%. La tendencia del coeficiente deconsanguinidad, por año de nacimiento de los animales, para la población fue 0,13%. Se observó que el valorpara las hembras de Registro de Pedigrí (n=22.174) fue del 4%; el estimado para las 394.239 hembras delRegistro de Crías fue del 3,3%. En los 6.150 machos el coeficiente de consanguinidad promedio calculadofue de 3,9%. La consanguinidad promedio para las hembras de la población Holando Argentino fue menor ala observada en poblaciones Holstein de otros países con lechería de relevancia. Sin embargo, debido a sutendencia positiva se sugiere considerar estrategias para controlar su incremento y así mantener una variacióngenética adecuada en las características de importancia económica.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243287,"idioma_id":4,"titulo":"Applicability of the Moyers' Probability Tables in Adolescents with Different Facial Biotypes","resumen":"Introduction:The Moyers? probability tables are used in mixed dentition analysis to estimate the extent of space required for the alignment ofcanines and premolars, by correlating the mesiodistal size of lower incisors with the size of permanent canines and premolars.Objective:This study intended to evaluate the applicability of the Moyer´s probability tables for predicting the mesiodistal space needed for thecorrect location of premolars and permanent canines non-erupted, in adolescents of the city of Cordoba, Argentina, who showdifferent facial biotypes.Materials and Methods:Models and tele-radiographies of 478 adolescents of both genders from 10 to 15 years of age were analyzed. The tele-radiographieswere measured manually in order to determine the facial biotype. The models were scanned with a gauged scanner (HP 3670) andmeasured by using Image Pro Plus 4.5 software.Results:According to this study, the comparison between the Moyer´s probability table, and the table created at the National University ofCórdoba (UNC) (at 95%, 75%, and 50%) shows that, in both tables, a higher value of mesiodistal width of lower incisorscorresponds to a bigger difference in the space needed for permanent canines and premolars; being the need for space for permanentscanines and premolars bigger in the UNC´s table. On the other hand, when contrasting the values of mesiodistal space for permanentcanines and premolars associated with each facial biotype, the discrepancies between groups were not statistically significant (P>0.05). However, we found differences in the size of the space required according to the mesiodistal width range of the lowerincisors for each biotype:a) The comparison of lower-range values, with a mesialdistal width of lower incisors less than 22 mm, the space required forpermanent canines and premolars resulted smaller in patients with dolichofacial biotype than in patients with mesofacial andbraquifacial biotypes. The latter biotypes have meager differences between them.b) The comparison of mid-range values, with a mesialdistal width of lower incisors from 22 to 25 millimeters, shows that the valuesof required alignment space are similar in the three facial biotypes.c) Finally, the comparison of upper range values, with a mesialdistal width of lower incisors greater than 25 millimeters, indicatesthat the space required for dolichofacial biotypes tends to be higher than in mesofacial and brachyfacial biotypes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243288,"idioma_id":4,"titulo":"Applicability of the Moyers' Probability Tables in Adolescents with Different Facial Biotypes","resumen":"Introduction:The Moyers? probability tables are used in mixed dentition analysis to estimate the extent of space required for the alignment ofcanines and premolars, by correlating the mesiodistal size of lower incisors with the size of permanent canines and premolars.Objective:This study intended to evaluate the applicability of the Moyer's probability tables for predicting the mesiodistal space needed for thecorrect location of premolars and permanent canines non-erupted, in adolescents of the city of Cordoba, Argentina, who showdifferent facial biotypes.Materials and Methods:Models and tele-radiographies of 478 adolescents of both genders from 10 to 15 years of age were analyzed. The tele-radiographieswere measured manually in order to determine the facial biotype. The models were scanned with a gauged scanner (HP 3670) andmeasured by using Image Pro Plus 4.5 software.Results:According to this study, the comparison between the Moyer´s probability table, and the table created at the National University ofCórdoba (UNC) (at 95%, 75%, and 50%) shows that, in both tables, a higher value of mesiodistal width of lower incisorscorresponds to a bigger difference in the space needed for permanent canines and premolars; being the need for space for permanentscanines and premolars bigger in the UNC´s table. On the other hand, when contrasting the values of mesiodistal space for permanentcanines and premolars associated with each facial biotype, the discrepancies between groups were not statistically significant (P>0.05). However, we found differences in the size of the space required according to the mesiodistal width range of the lowerincisors for each biotype:a) The comparison of lower-range values, with a mesialdistal width of lower incisors less than 22 mm, the space required forpermanent canines and premolars resulted smaller in patients with dolichofacial biotype than in patients with mesofacial andbraquifacial biotypes. The latter biotypes have meager differences between them.b) The comparison of mid-range values, with a mesialdistal width of lower incisors from 22 to 25 millimeters, shows that the valuesof required alignment space are similar in the three facial biotypes.c) Finally, the comparison of upper range values, with a mesialdistal width of lower incisors greater than 25 millimeters, indicatesthat the space required for dolichofacial biotypes tends to be higher than in mesofacial and brachyfacial biotypes.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243296,"idioma_id":5,"titulo":"Simulación de Flujo Transitorio 2D alrededor de un Cilindro Circular Horizontal considerando el Efecto Suelo","resumen":"Las estructuras cilíndricas cercanas a una superficie sólida tienen diversas y numerosas aplicaciones dentro de la ingeniería actual. Si bien, la dinámica del flujo alrededor de un cilindro circular aislado ubicado dentro de un flujo uniforme está razonablemente bien comprendida, este no es el caso cuando el cilindro se encuentra posicionado cercano a una pared. La incidencia en el flujo y las presiones inducidas sobre el cilindro se estudian mediante dinámica de fluidos computacional (CFD, por su siglas en inglés) por medio del código FLUENT, que implementa el método de volúmenes finitos. Para tal fin se considera flujo bidimensional y transitorio, el cual está basado en un esquema bounded second-order implicit; además se implementa el modelo de turbulencia SAS (Scale-Adaptive Simulation). Se analizan los efectos del cambio de la separación (G) entre el cilindro (de diámetro D) y la pared, para diferentes números de Reynolds y distintos espesores de capa límites del suelo. Se examinan  los coeficientes de sustentación y de arrastre y el comportamiento de desprendimiento del vórtice (número de Strouhal, St). Los resultados numéricos son comparados con valores disponibles en la literatura de ensayos experimentales en túnel de viento mostrando que tanto el coeficiente de arrastre como de sustentación dependen fuertemente de la relación de separación (G\/D), y están afectados por la capa límite del suelo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243300,"idioma_id":5,"titulo":"Vigencia del Marxismo","resumen":"El marxismo ha devenido inextricable de la ideología capitalista. Dicho lo cual, la pregunta sobre su vigencia queda respondida.  Pero para justificar esa aseveración, discutir su sentido, precisar su alcance, conviene descomponer la cuestión en al menos estas tres: a) ¿está vigente el marxismo, entendido como la doctrina marxista?; b) ¿está vigente el ?socialismo científico?, ya no entendido como doctrina, sino como estrategia de liberación obrera para la prosecución del progreso humano?, y c) ¿tiene significado la expresión ?doctrina marxista?? En otra oportunidad discutiremos a fondo, como lo venimos haciendo, las formulaciones b) y c) de la pregunta, las cuales reclaman entrar en el terreno propiamente teórico del socialismo científico. La a), en cambio, se agota pronto, y la ocasión es propicia para detenerse en ella; cosa que haremos en las próximas páginas. Sobre las b) y c) nos limitaremos a un par de sugerencias brevísimas. En todo caso quedará bosquejado un trabajo mayor, para ser compartido.Ahora bien. Consideradas en este orden las tres formulaciones de la pregunta, se advertirá que cada una pone un contexto más determinado a la noción de ?vigencia?; en cada uno daremos una respuesta, que suscitará otra pregunta.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243302,"idioma_id":5,"titulo":"El hombre como pregunta, asombro, esperanza. Una lectura latinoamericana de Platón: Arturo Andrés Roig","resumen":"Eltrabajo se orienta a indagar en la relectura que lleva adelante Arturo AndrésRoig de Platón. Filosofar es para Platón un acto de libertad puesto demanifiesto en la experiencia. Roig apela a esta tesis como punto de partidapara recorrer la obra platónica, a partir de allí enuncia una definición de serhumano como pregunta, asombro y esperanza. Se sostiene que en el análisis de laobra platónica se actualiza una indagación persistente de Roig: la cuestión delsujeto.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243303,"idioma_id":5,"titulo":"Valorización económica, social y ambiental de la desertificación en el Departamento Santa María, provincia de Catamarca.","resumen":"Este trabajo presenta los resultados del estudio de valorización integral de la desertificación en el departamento Santa María,provincia de Catamarca. El método de valorización utilizado combina herramientas de la economía ambiental y economíaecológica, realizando un análisis de todo el sistema, a través de la integración de resultados. El trabajo desarrolló un métodopara valorar la pérdida de secuestro de carbono en la cuenca entre 1997 y 2012. Los resultados obtenidos indican que ladesertificación ha aumentado en el todos los casos, excepto en una localidad. Se evidencia también, problemassocioeconómicos, como bajos ingresos, alto porcentaje de población que vive bajo la línea de pobreza e indigencia, como asíescaza capacitación de los pobladores en temas ambientales y baja percepción de la desertificación como un problema. Laspérdidas por desertificación representan un 2.4% del Producto Bruto Geográfico de la provincia. Las emisiones de CO2, de lacuenca, representan el 0,14% de las emisiones del país como consecuencia de los procesos de deterioro ambiental que sehan producido en la zona. Todos estos resultados indican que se necesitan medidas urgentes para revertir estos procesos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243305,"idioma_id":5,"titulo":"El par cómico en la comedia temprana de Aristófanes y su pervivencia en Lisístrata","resumen":"La noción de par cómico, definida como un par tópico compuesto por dos personajes opuestos y antagónicos, constituye una clave fundamental para comprender la comedia temprana de Aristófanes. Este esquema binario domina en las primeras comedias conservadas del autor y se vuelve a implementar en su forma más convencional en Lisístrata. Su utilización en Lisístrata se debe, entre otros motivos, al hecho de que esta pieza retoma la virulencia satírica de las primeras obras y la polémica a favor de la paz con Esparta, tema presente en todas las comedias tempranas conservadas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243306,"idioma_id":5,"titulo":"El par cómico homérico y su proyección sobre el par cómico aristofánico","resumen":"El trabajo intenta demostrar la existencia de un par cómico homérico, integrado por dos personajes opuestos y antagónicos, el burlador y el burlado, que constituyen el nudo semántico del episodio. El héroe es portavoz del discurso positivo y ocupa el lugar del vencedor y burlador de su oponente. La comedia aristofánica temprana se nutre del esquema homérico, entre otros antecedentes, para construir sus personajes protagonistas: el burlador y el burlado, el vencedor y el vencido, el portavoz del discurso avalado en la pieza y el portavoz del discurso atacado. Si bien Whitman (1964), entre otros, ha destacado los paralelismos entre Odiseo y el héroe aristofánico, no se ha analizado la incidencia del par homérico completo, el burlador y el burlado, sobre el par aristofánico. Nuestro trabajo desplaza el eje de análisis de la figura del héroe hacia el concepto de par cómico. En definitiva, analiza los personajes tópicos homéricos que inciden en la construcción del par aristofánico.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243308,"idioma_id":4,"titulo":"Effect of outdoor air pollution on asthma exacerbations in children and adults: Systematic review and multilevel meta-analysis","resumen":"BACKGROUND:Several observational studies have suggested that outdoor air pollution may induce or aggravate asthma. However, epidemiological results are inconclusive due to the presence of numerous moderators which influence this association. The goal of this study was to assess the relationship between outdoor air pollutants and moderate or severe asthma exacerbations in children and adults through a systematic review and multilevel meta-analysis.MATERIAL AND METHODS:We searched studies published in English on PubMed, Scopus, and Google Scholar between January 2000 and October 2016. Studies following a case-crossover design with records of emergency departments and\/or hospital admissions as a surrogate of moderate or severe asthma exacerbations were selected. A multilevel meta-analysis was employed, taking into account the potential clustering effects within studies examining more than one lag. Odds ratios (ORs) and 95% confidence intervals were estimated. A subgroup analysis in children aged 0 to 18 years and a sensitivity analysis based on the quality of the included studies as defined in the Newcastle-Ottawa Scale were performed. Publication bias was evaluated through visual inspection of funnel plots and by a complementary search of grey literature. (Prospero Registration number CRD42015032323).RESULTS:Database searches retrieved 208 records, and finally 22 studies were selected for quantitative analysis. All pollutants except SO2 and PM10 showed a significant association with asthma exacerbations (NO2: 1.024; 95% CI: 1.005,1.043, SO2: 1.039; 95% CI: 0.988,1.094), PM10: 1.024; 95% CI: 0.995,1.053, PM2.5: 1.028; 95% CI: 1.009,1.047, CO: 1.045; 95% CI: 1.005,1.086, O3: 1.032; 95% CI: 1.005,1.060. In children, the association was significant for NO2, SO2 and PM2.5.CONCLUSION:This meta-analysis provides evidence of the association between selected air pollutants and asthma exacerbations for different lags.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243309,"idioma_id":5,"titulo":"Una mirada a la integración de los valores desde el rol de las TIC","resumen":"Concibiendo a las nuevas formas de aprender como oportunidades de acercamiento sin límites de espacio ni de tiempo, el presente trabajo indaga las posibles asociaciones entre las intenciones docentes de integrar los valores en los espacios de enseñanza, la utilización de las tecnologías que facilitarían la concreción de estas intenciones y la información obtenida de los estudiantes, tanto desde sus percepciones acerca del trabajo colaborativo como del grupo focal. Los datos recabados permiten obtener un acercamiento a la información buscada. Los resultados obtenidos dan cuenta de la ponderación atribuida a las Tecnologías de la Información y Comunicación (tic) como instrumentos promotores de valores desde sus diferentes entornos. Como todo accionar educativo, el uso de las tic conlleva una interpretación de los actores que trasciende la esfera de lo meramente técnico hacia oportunidades que pueden marcar la diferencia pese a las limitaciones que imponen muchas realidades del contexto ético-moral.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243312,"idioma_id":4,"titulo":"Minimal dynamical description of eye movements","resumen":"In this paper we have addressed the question of whether a simple set of functions being the solution of a model, namely the damped harmonic oscillator with a general driving force, can satisfactorily describe data corresponding to ocular movements produced during a visual search task. Taking advantage of its mathematical tractability, we first focused on the simplest driving force compatible to the experimental data, a step-like activation. Under this hypothesis we were able to further simplify the system, once data from several experiments were fitted, producing an essentially parameter-free model that we plan to use in future applications. To increase the quality of the description of individual movements, we expanded the complexity in the forcing term and solved the inverse problem by using a proper mathematical formalism. Furthermore, additional terms, those arising from ocular drift and tremor, may be included within the same mathematical approach.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243313,"idioma_id":4,"titulo":"Selforganization of modular activity of grid cells","resumen":"A unique topographical representation of space is found in the concerted activity of grid cells in the rodent medial entorhinal cortex. Many among the principal cells in this region exhibit a hexagonal firing pattern, in which each cell expresses its own set of place fields (spatial phases) at the vertices of a triangular grid, the spacing and orientation of which are typically shared with neighboring cells. Grid spacing, in particular, has been found to increase along the dorso-ventral axis of the entorhinal cortex but in discrete steps, that is, with a modular structure. In this study, we show that such a modular activity may result from the self-organization of interacting units, which individually would not show discrete but rather continuously varying grid spacing. Within our ?adaptation? network model, the effect of a continuously varying time constant, which determines grid spacing in the isolated cell model, is modulated by recurrent collateral connections, which tend to produce a few subnetworks, akin to magnetic domains, each with its own grid spacing. In agreement with experimental evidence, the modular structure is tightly defined by grid spacing, but also involves grid orientation and distortion, due to interactions across modules. Thus, our study sheds light onto a possible mechanism, other than simply assuming separate networks a priori, underlying the formation of modular grid representations.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243314,"idioma_id":5,"titulo":"El personaje lector: un legado quijotesco contra la violencia latinoamericana","resumen":"En las dos novelas que se analizan en este trabajo, Amuleto, de Roberto Bolaño (1999) e Insensatez, de Horacio Castellanos Moya (2004), los protagonistas son personajes lectores que enfrentan de lleno la violencia estatal latinoamericana en forma de masacre. Oscilando entre la locura y la lectura como modo de relacionarse con el mundo, los dos textos presentan una matriz cervantina en la construcción de sus personajes centrales. La propuesta es que frente a situaciones de violencia histórica concreta, los escritores latinoamericanos contemporáneos encuentran en el Quijote una figura generadora  de nuevos personajes, a través de procedimientos de inversión y desvío.  Si en el Quijote  el protagonista busca mediante la lectura un modo de escapar de una realidad mediocre y asfixiante, en las novelas latinoamericanas contemporáneas los personajes centrales hacen de la lectura una respuesta a la violencia desatada e incontrolable.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243316,"idioma_id":5,"titulo":"La interversión de título en el Derecho argentino","resumen":"El derecho argentino reconoce dos clases de relaciones de poder, consistentes en vínculos de hecho con las cosas cuya existencia no requiere de antecedentes jurídicos: la posesión y la tenencia. El mecanismo por el cual un sujeto puede pasar de una relación de poder a otra se denomina interversión de título, y el presente trabajo analiza los elementos y condiciones necesarios para que se produzca este fenómeno de acuerdo a la normativa del Código Civil y Comercial de la Nación y a la jurisprudencia actual.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243317,"idioma_id":5,"titulo":"Violeta Palacios y Marcela Alejandra Suárez. Terencio: nuevas lecturas y perspectivas.","resumen":"Notas:1) Lo publicado es una reseña. No tiene abstract.2) La publicación del número 44 de la revista es, por el mmomento, digital. Está en prensa. Por ello el mes completado no es preciso. Es completado solo a fines del requerimiento del sistema informático.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243319,"idioma_id":5,"titulo":"Determinación de cloro activo en diferentes soluciones de hipoclorito de sodio","resumen":"El hipoclorito de sodio, en sus diferentes concentraciones, constituye la primera elección como sustancia irrigadora de los conductos radiculares. Es por esto la importancia de mantener las concentraciones para obtener una buena desinfección El objetivo de este estudio fue determinar la cantidad de cloro activo presente en diferentes marcas comerciales de hipoclorito de sodio.Se seleccionaron diferentes marcas comerciales de hipoclorito de sodio, la evaluación del cloro activo se realizó mediante el método titulación de óxido-reducción. El 100% de las marcas comerciales no presentó la cantidad de cloro activo declarada por el fabricante (46,6 +\/15,68), en todas las muestras analizadas en laboratorio los resultados obtenidos fueron menores (39,57 +\/12,14) a los especificados por el fabricante con una diferencia estadísticamente significativa (p < 0.01)Esta investigación permite evaluar un aspecto relevante dentro del campo de la terapia endodóntica, mejorando los estándares de calidad de las prácticas clínicas.ABSTRACTSodium hypochlorite, at different concentrations, is the first choice as substance irrigating root canals. That is why the importance of maintaining concentrations to obtain good disinfection The aim of this study was to determine the amount of active chlorine in different brands of sodium hypochlorite. different brands of sodium hypochlorite were selected, evaluation of active chlorine was performed by redox method. The 100% trademarks not presented the amount of active chlorine declared by the manufacturer (46.6 + \/ 15.68) in all samples analyzed in the laboratory results obtained were lower (39.57 + \/ 12.14) to those specified by the manufacturer with a statistically significant difference (p <0.01). This research evaluates a relevant aspect within the field of endodontic therapy, improving the quality standards of clinical practice.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243321,"idioma_id":4,"titulo":"Effect of hyper thyroidism on circulating prolactin and hypothalamic expression of tyrosine hydroxylase, prolactin signaling cascade members and estrogen and progesterone receptors during late pregnancy and lactation in the rat.","resumen":"Hyperthyroidism (HyperT) compromises pregnancy and lactation, hindering suckling-induced PRL release. We studied the effect of HyperT on hypothalamic mRNA (RT-qPCR) and protein (Western blot) expression of tyrosine hydroxylase (TH), PRL receptor (PRLR) and signaling pathway members, estrogen-&#945; (ER&#945;) and progesterone (PR) receptors on late pregnancy (days G19, 20 and 21) and early lactation (L2) in rats. HyperT advanced pre-partum PRL release, reduced circulating PRL on L2 and increased TH mRNA (G21 and L2), p-TH, PRLR mRNA, STAT5 protein (G19 and L2), PRLR protein (G21) and CIS protein (G19). PRs mRNAs and protein decreased on G19 but afterwards PRA mRNA (G20), PRB mRNA (G21) and PRA mRNA and protein (L2) increased. ER&#945; protein increased on G19 and decreased on G20. Thus, the altered hypothalamic PRLR, STAT5, PR and ER&#945; expression in hyperthyroid rats may induce elevated TH expression and activation, that consequently, elevate dopaminergic tone during lactation, blunting suckling-induced PRL release and litter growth.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243323,"idioma_id":4,"titulo":"Thyroid Hormone Controls Breast Cancer Cell Movement via Integrin &alpha;V\/&beta;3\/SRC\/FAK\/PI3-Kinases","resumen":"Thyroid hormones (TH) play a fundamental role in diverse processes, including cellular movement. Cell migration requires the integration of events that induce changes in cell structure towards the direction of migration. These actions are driven by actin remodeling and stabilized by the development of adhesion sites to extracellular matrix via transmembrane receptors linked to the actin cytoskeleton. Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that promotes cell migration and invasion through the control of focal adhesion turnover. In this work, we demonstrate that the thyroid hormone triiodothyronine (T3) regulates actin remodeling and cell movement in breast cancer T-47D cells through the recruitment of FAK. T3 controls FAK phosphorylation and translocation at sites where focal adhesion complexes are assembled. This process is triggered via rapid signaling to integrin &#945;V\/&#946;3, Src, phosphatidylinositol 3-OH kinase (PI3K), and FAK. In addition, we established a cellular model with different concentration of T3 levels: normal, absence, and excess in T-47D breast cancer cells. We found that the expression of Src, FAK, and PI3K remained at normal levels in the excess of T3 model, while it was significantly reduced in the absence model. In conclusion, these results suggest a novel role for T3 as an important modulator of cell migration, providing a starting point for the development of new therapeutic strategies for breast cancer treatment.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243329,"idioma_id":5,"titulo":"Consenso para el uso adecuado de antibi&oacute;ticos en el ni&ntilde;o menor de 36 meses con fiebre sin foco de infecci&oacute;n evidente. Resumen Ejecutivo","resumen":"La fiebre es uno de los motivos de consultamás frecuentes en pediatría. A pesar de losavances, el abordaje de los niños menores de36 meses con fiebre sin foco de infección es untema de debate y un desafío para el pediatra.Si bien la mayoría de las veces la fiebre es deetiología viral y autolimitada, también puedeestar ocasionada por una infección grave. Esnecesario considerar que el riesgo de infecciónbacteriana grave es mayor en los niños menoresde 60-90 días y enfatizar las estrategias paraidentificar a los que tienen bajo riesgo dedesarrollar infecciones graves para evitar el usoinadecuado de antibióticos. La infección urinariaes la patología bacteriana más frecuente en estosniños. Los agentes etiológicos más usuales varíande acuerdo con la edad y también se deben teneren cuenta las modificaciones que ocurrieroncon estos, relacionadas con la incorporación devacunas al calendario nacional.Con el objetivo de mejorar el uso de elementosdiagnósticos, indicaciones de antibióticosempíricos y minimizar riesgos en la atenciónde pacientes con potencial infección bacterianagrave, se actualizó este documento, a la luz dela evidencia científica, principalmente, parael óptimo abordaje frente al niño menor de 36meses con fiebre sin foco evidente en la atenciónambulatoria. Es fundamental la evaluaciónclínica exhaustiva y reiterada, conjuntamentecon parámetros de laboratorio, para establecerlos diagnósticos probables y mejorar la calidadde atención de los niños","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243331,"idioma_id":5,"titulo":"La persona humana y la protección de los derechos de la vivienda","resumen":"El CCyC reafirma el resguardo a bienes humanos básicos que la sociedad actual reconoce de protección necesaria, como la dignidad de la persona, la libertad de conciencia, la autonomía de decisión, la vida, la salud, entre otros, que se enlazan naturalmente con la necesidad del hombre de tener un ámbito o morada adecuada para el desarrollo integral de su personalidad.La protección de la vivienda es un tema complejo ya que puede ser abordado desde diferentes aristas, que van desde el respeto a la dignidad de la persona en sí, hasta cuestiones de orden familiar, patrimonial, sucesorio, registral, tributario, etc. Además muchos de estos aspectos se vinculan con el derecho de propiedad, y en numerosas ocasiones los derechos reconocidos en cada uno de esos ámbitos confrontan entre sí. En lo que hace al eje de este trabajo, la vivienda como derecho humano que tiende a la protección de la persona humana en sí, hay que distinguir dos aspectos: a) el derecho al acceso a una vivienda digna y b) la protección de la  vivienda que ya se habita . Otra perspectiva a considerar es el derecho que los terceros pueden tener sobre la vivienda que se protege.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243334,"idioma_id":5,"titulo":"Transient congenital hypothyroidism due to biallelic defects of DUOX2 gene. Two clinical cases Hipotiroidismo cong&eacute;nito transitorio por defectos bial&eacute;licos del gen DUOX2. Dos casos clinicos","resumen":"Congenital hypothyroidism affects 1:2000-3000 newborns detected by neonatal screening programs. Dual oxidases, DUOX1 and 2, generate hydrogen peroxide needed for the thyroid hormone synthesis. Mutations in the DUOX2 gene have been described in transient and permanent congenital hypothyroidism. Two brothers with congenital hypothyroidism detected by neonatal screening with eutopic gland and elevated thyroglobulin are described. They were treated with levothyroxine until it could be suspended in both during childhood, assuming the picture as transient. Organification disorder was confirmed. Both patients were compounds heterozygous for a mutation in exon 9 of the paternal allele (c.1057-1058delTT, p.F353PfsX36 or p.F353fsX388) and in exon 11 of the maternal allele (c.1271T > G, p.Y425X) of DUOX2 gene. Our finding confirms that the magnitude of the defect of DUOX2 is not related to the number of inactivated alleles, suggesting compensatory mechanisms in the peroxide supply.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243335,"idioma_id":4,"titulo":"2016 Annual Meeting of the Sociedad Latinoamericana de Endocrinología Pediátrica (SLEP) Buenos Aires, Argentina (November 8-11, 2016), Selected Highlights","resumen":"adjunto","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243336,"idioma_id":4,"titulo":"Alternative Therapies for PKU","resumen":"The phenylalanine (PHE)-restricted diet has improved in quality and diversity over time and has proven to be effective in allpatients. Nevertheless, this treatment imposes a heavy social and economic burden to patient and family and impacts quality of life.Sustained adherence to PHE restriction is difficult to maintain. Moreover, even patients with phenylketonuria (PKU) with normalintelligence quotient (IQ) have lower IQ than matched individuals without PKU and can have deficits in multiple other aspects ofneuropsychological function, including cognitive and executive function, working memory. They can also have behavior problems,depression, and low self-esteem. In recent years, alternative treatments for PKU have been developed and their use has beenindicated for some patients who are candidates for options besides traditional treatment. Sapropterindihydrochloride, largeneutral amino acids, and glycomacropeptide are alternative treatment options in use for selected patients. The aim of this article isto review the current knowledge of these new approaches to PKU treatment","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243337,"idioma_id":4,"titulo":"Prospective and descriptive study on serum androstenedione concentration in healthy children from birth until 18 Years of age and its associated factors","resumen":"Introduction. Androstenedione (A4) is an adrenal and gonadal steroid biomarker, useful in the assessment of children in whom steroidogenic disorders are suspected. The first key step in the evaluation of a diagnostic test resides on confident reference intervals (RI). The lack of updated A4-RI with current methods in pediatrics may mislead A4 results and limit its diagnosis accuracy. Aim. To provide A4 reference ranges in healthy children. Methods. Prospective, descriptive study. 283 children aged 4 days to 18 years were included. In children<1 yr, A4 was measured directly in serum (NE-A4) and postorganic solvent extraction (E-A4) for the assessment of interfering steroids. The influence of chronological age (CA), gender, and Tanner stage (T) were investigated. Results. In the neonatal period, E-A4 was significantly lower than NE-A4; boys had higher NE-A4; sexual dimorphism disappeared after extraction procedure. In children older than 4 months, A4 concentration remained low until the age of 5 years. Thereafter, A4 increased significantly in association with CA and T (r2=0.65; p<0.001), obtaining the highest concentrations in children within pubertal ages without sexual dimorphism. Conclusion. We recommend to perform solvent extraction in neonates and to take into account age and sexual development to properly interpret A4 results in childhood.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243338,"idioma_id":4,"titulo":"Pilot Neonatal Screening Program for Central Congenital Hypothyroidism: Evidence of Significant Detection","resumen":"Background\/Aim: Congenital hypothyroidism (CH) is a heterogeneous entity. Neonatal screening programs based on thyrotropin (TSH) determination allow primary CH diagnosis but miss central CH (CCH). CCH causes morbidity, alerts to other pituitary deficiencies, and is more prevalent than previously thought. We aimed at developing a pilot neonatal screening program for CCH detection. Patients and Methods: A prospective 2-year pilot neonatal screening study based on simultaneous dried blood specimen TSH and thyroxine (T4) measurements was implemented in term newborns aged 2-7 days. Those with T4 &#8804;4.5 &#956;g\/dL (-2.3 SDS) and TSH <10 mIU\/L were recalled (suspicious of CCH) and underwent clinical and biochemical assessment performed by expert pediatric endocrinologists. Results: A total of 67,719 newborns were screened. Primary CH was confirmed in 24 (1: 2,821). Forty-four newborns with potential CCH were recalled (recall rate 0.07%) at a mean age of 12.6 ± 4.8 days. In this group, permanent CCH was confirmed in 3 (1: 22,573), starting L-T4 treatment at a mean age of 12.3 ± 6.6 days; 14 boys showed T4-binding globulin deficiency (1: 4,837); 24 had transient hypothyroxinemia (21 non-thyroidal illness and 3 healthy); and 3 died before the confirmation stage. According to initial free T4 measurements, CCH patients had moderate hypothyroidism. Conclusions: Adding T4 to TSH measurements enabled the identification of CCH as a prevalent condition and contributed to improving the care of newborns with congenital hypopituitarism and recognizing other thyroidal disorders.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243339,"idioma_id":5,"titulo":"LA POLÍTICA DE SUELO URBANO EN LOS GOBIERNOS LOCALES. EL CASO DE RÍO  GRANDE, TIERRA DEL FUEGO, ARGENTINA","resumen":"Este trabajo pretende abordar la forma en que los gobiernos locales argentinos intervienen en la construcción de la ciudad a través de la gestión del suelo urbano. Se analiza el caso de la política de suelo urbano del municipio de Río Grande (Tierra del Fuego) durante el periodo 1991-2015. La metodología es de carácter cualitativo a través del análisis de la normativa local de suelo urbano.La hipótesis sostiene que en dicho municipio durante el periodo 1991-2010 la política de suelo urbano se ha orientado más a la regulación y administración de la ciudad y al fomento de actividades industriales y productivas que a la generación de suelo urbano aunque dicha tendencia cambia en 2010 a partir de la incorporación de ciertos instrumentos. Una primera aproximación nos permite corroborar la hipótesis inicial aunque sostendremos que la mera creación de instrumentos es condición necesaria pero no suficiente para la producción de suelo urbano. Palabras claves: políticas de suelo urbano, suelo, gobiernos locales, construcción de ciudad, recuperación de plusvalías.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243340,"idioma_id":4,"titulo":"High virulence of methicillin resistant Staphylococcus aureus ST30-SCC mec IVc- spa t019, the dominant community-associated clone in Argentina","resumen":"Community-acquired methicillin resistant Staphylococcus aureus emerged as a worldwide health problem in the last few years. In Argentina, it is found in 70% of skin and skin structure infections in previously healthy adult patients and causes severe invasive diseases. The ST30-SCCmecIVc-spat019 clone is predominant in adult infections and has displaced the previously prevalent ST5-SCCmecIVa-spat311 clone in community settings. In the present work we compared the virulence of both clones in order to explain the displacement, and found that ST30-IVc is associated with invasive infections in adult patients from Argentina and possesses a different virulence-associated genes profile compared to ST5-IVa. A representative strain of ST30 lineage has a more aggressive behavior in animal models of infection and expresses higher level of Fibronectin binding protein A coding gene, which could enhance the bacterial invasion capacity.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243341,"idioma_id":4,"titulo":"On the Feasibility of External Factual Support as Wikipedia?s Quality Metric","resumen":"Developing metrics to estimate the information quality of Wikipedia articles is an interesting and important research area. In this article, we propose and analyze the feasibility, of a new quality metric based on the ?external factual support? of an article. The rationale behind this metric is identified, a formal definition of the metric is presented and some implementation aspects are introduced. Preliminary results show the feasibility of our proposal and its potential to discriminate high quality versus low-quality Wikipedia?s articles.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243342,"idioma_id":4,"titulo":"A simple method for recommending specialized specifications for diabetes monitoring","resumen":"Under glycemic variability, a characterization of the desired blood glucose (BG) behavior is needed to assess if a given artificial pancreas (AP) respects its specification. The specification is an essential element to detect any deviation from an adequate insulin policy. Specializing the monitoring specification is therefore of utmost importance as existing guidelines for diabetes management are general and do not take into account how the personal factors and lifestyle affect the glycemic behavior. Surely, recommending personalized monitoring specifications may provide flexible and appropriate treatment goals to be attained by diabetic patients in order to account for their actual treatment needs. In this work, we use machine learning models to characterize glycemic behavior in synthetic healthy individuals. To account for the day-by-day fluctuation in BG levels, we use a stochastic process superimposed on a deterministic model of the glucose-insulin dynamics. The obtained characterization of the glycemic behavior in healthy individuals is then used as the target class to predict, and thus recommend, personalized monitoring specifications to diabetic patients. Results show that the approach stands as a feasible strategy to recommending appropriate and realistic monitoring goals for diabetic patients based on healthy individuals who share a similar glycemic behavior. Eventually, the incorporation of a recommender approach on an intelligent monitoring system for the AP will allow on-line adaptation of the treatment requirements for each patient.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243345,"idioma_id":5,"titulo":"Estimación de la pendiente de ahuellamiento en el ensayo de Wheel Tracking Test, en vistas a las nuevas exigencias del Pliego DNV-2017","resumen":"no corresponde.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243346,"idioma_id":4,"titulo":"Corticosterone levels and immunological indices in stressed juvenile broad-snouted caimans","resumen":"The effect of stress in wild vertebrates has been little investigated, especially in crocodilians. In the wild, crocodilians face numerous stressors such as climatic factors,toxicant exposure, and infection. Exposure to stressors may affect the physiological processes of crocodilians, with consequences on its fitness and survival. We experimentally investigated the effect of a 4-week exposure to environmental challenges (food restriction, water restriction and high temperature) on growth, immunological investment and corticosterone levels of juvenile Caiman latirostris. White blood cells counts, natural antibody (NAb) levels and complement system activity were evaluated to characterize the influence of those treatments on the immune system. We found deprivation of food resulted in reduction in growth and body condition, whereas high temperature had a beneficial effect on the variables measured. Individuals exposed to heat treatment (37  1°C) grew more, and obtained better body condition, higher NAb levels, and significantly lower corticosterone levels relative to caimans in all other groups. Food restricted caimans also illustrated higher NAb levels. Our findings suggest that C. latirostris juveniles are able to tolerate environmental stressors and they are even favored by high temperatures.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243347,"idioma_id":4,"titulo":"In Silico Analysis of Fatty Acid Desaturase Genes and Proteins in Grasses","resumen":"Fatty acid desaturases (FADs) catalyze the introduction of a double bond into acylchains. Two FAD groups have been identified in plants: acyl-acyl carrier proteins (ACPs) and acyl-lipid or membrane-bound FAD. The former catalyze the conversion of 18:0 to 18:1 and to date have only been identified in plants. The latter are found in eukaryotes and bacteria and are responsible for multiple desaturations. In this study, we identified 82 desaturase gene and protein sequences from 10 grass species deposited in GenBank that were analyzed using bioinformatic approaches. Subcellular localization predictions of desaturase family revealed their localization in plasma membranes, chloroplasts, endoplasmic reticula, and mitochondria. The in silico mapping showed multiple chromosomal locations in most species. Furthermore, the presence of the characteristic histidine domains, the predicted motifs, and the finding of transmembrane regions strongly support the protein functionality. The identification of putative regulatory sites in the promotor and the expression profiles revealed the wide range of pathways in which fatty acid desaturases are involved. This study is an updated survey on desaturases of grasses that provides a comprehensive insight into diversity and evolution. This characterization is a necessary first step before considering these genes as candidates for new biotechnological approaches.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243348,"idioma_id":5,"titulo":"Las coincidencias del pensamiento de John H. Williams y Raúl Prebisch acerca del orden económico internacional de posguerra","resumen":"Este trabajo indagaen las similitudes del pensamiento de Williams y Prebisch sobre el sistemamonetario internacional, y analiza la articulación conceptual entre losintereses oficiales estadounidenses y los países periféricos en los albores deBretton Woods, a través de la reinterpretación de las cuentas del balance depagos, basada en la teoría de la interdependencia y complementariedad centro-periferia,visión que ambos economistas compartieron. John H. Williams,profesor de Harvard y vicepresidente del Banco de la Reserva Federal deNueva York, propuso el ?plan de la moneda clave?, que el FMI adoptó de hecho trasla muerte de Roosevelt, en 1945. Raúl Prebisch mantuvo con Williams unarelación de amistad y trabajo desde 1920, e impulsó la industrialización de lospaíses periféricos acorde al nuevo orden económico mundial, bajo la hegemoníaestadounidense, y con el capital extranjero como requisito necesario, reflejandoel aparato conceptual aquí analizado.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243350,"idioma_id":5,"titulo":"La nueva deuda pública argentina","resumen":"A fin de 2016 la deuda&nbsp; del sector público nacional bordeaba el 57% del PIB . Según estimaciones oficiales, su monto totalizaba 4,6 billones de pesos, equivalente a 288,4 miles de millones de dólares al tipo de cambio de 15,85 pesos por dólar (ver anexos, Cuadro 1), y se denominaba un 40% en pesos y 60% en moneda extranjera. Con las colocaciones del primer trimestre de 2017, esta deuda alcanzó unos 310 mil millones de dólares, y se acercó al 60% del PIB. Como las emisiones excedieron los vencimientos pagados, en 2016 el endeudamiento aumentó 1,3 billones de pesos (+38%), equivalentes a 34,5 mil millones de dólares (+13%, al tipo de cambio mencionado). A estas se cifras deben agregar las emisiones de diciembre de 2015 y las del primer trimestre de 2017, unos 25 mil millones de dólares, según el programa financiero del gobierno, y detraer 7,3 mil millones de dólares del bono Bonar X, pagado en abril de este año.&nbsp;","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243355,"idioma_id":4,"titulo":"Development of a General Aza-Cope Reaction Trigger Applied to Fluorescence Imaging of Formaldehyde in Living Cells","resumen":"Formaldehyde (FA) is a reactive signaling molecule that is continuously produced through a number of central biological pathways spanning epigenetics to one-carbon metabolism. On the other hand, aberrant, elevated levels of FA are implicated in disease states ranging from asthma to neurodegenerative disorders. In this context, fluorescence-based probes for FA imaging are emerging as potentially powerful chemical tools to help disentangle the complexities of FA homeostasis and its physiological and pathological contributions. Currently available FA indicators require direct modification of the fluorophore backbone through complex synthetic considerations to enable FA detection, often limiting the generalization of designs to other fluorophore classes. To address this challenge, we now present the rational, iterative development of a general reaction-based trigger utilizing 2-aza-Cope reactivity for selective and sensitive detection of FA in living systems. Specifically, we developed a homoallylamine functionality that can undergo a subsequent self-immolative &#946;-elimination, creating a FA-responsive trigger that is capable of masking a phenol on a fluorophore or any other potential chemical scaffold for related imaging and\/or therapeutic applications. We demonstrate the utility of this trigger by creating a series of fluorescent probes for FA with excitation and emission wavelengths that span the UV to visible spectral regions through caging of a variety of dye units. In particular, Formaldehyde Probe 573 (FAP573), based on a resorufin scaffold, is the most red-shifted and FA sensitive in this series in terms of signal-to-noise responses and enables identification of alcohol dehydrogenase 5 (ADH5) as an enzyme that regulates FA metabolism in living cells. The results provide a starting point for the broader use of 2-aza-Cope reactivity for probing and manipulating FA biology.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243356,"idioma_id":4,"titulo":"Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism","resumen":"The folate-driven one-carbon (1C) cycle is a fundamental metabolic hub in cells that enables the synthesis of nucleotides and amino acids and epigenetic modifications. This cycle might also release formaldehyde, a potent protein and DNA crosslinking agent that organisms produce in substantial quantities. Here we show that supplementation with tetrahydrofolate, the essential cofactor of this cycle, and other oxidation-prone folate derivatives kills human, mouse and chicken cells that cannot detoxify formaldehyde or that lack DNA crosslink repair. Notably, formaldehyde is generated from oxidative decomposition of the folate backbone. Furthermore, we find that formaldehyde detoxification in human cells generates formate, and thereby promotes nucleotide synthesis. This supply of 1C units is sufficient to sustain the growth of cells that are unable to use serine, which is the predominant source of 1C units. These findings identify an unexpected source of formaldehyde and, more generally, indicate that the detoxification of this ubiquitous endogenous genotoxin creates a benign 1C unit that can sustain essential metabolism.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243359,"idioma_id":5,"titulo":"La dinámica industrial actual en Argentina y los actores socioproductivos pymes en la economía regional mendocina. Un análisis del complejo agroindustrial frutihortícola","resumen":"En el contexto económico político reciente de Argentina, la industria en general y las pymes en particular sufren limitaciones de tipo coyuntural que expresan aspectos estructurales legados del avance del neoliberalismo en toda la región: efectos contrapuestos de la apertura económica, predominancia de la producción e inversión en commodities demandados en el mercado internacional, expansión de los servicios por sobre la industria manufacturera, escaso proceso de re-inversión en capital productivo que, en conjunto, aunque con heterogeneidades, denotan un exiguo desarrollo industrial.A partir del estudio de la situación de la economía regional mendocina, particularmente del complejo agroindustrial, buscamos discernir indicios de destrucción o reinvención de la producción industrial. Basados en una perspectiva sociológica, diferenciamos en el análisis la composición del complejo en términos de agentes productivos, su participación y prácticas a partir de los cambios recientes. Mediante el seguimiento de tres casos de pymes agroindustriales, ponemos a consideración la siguiente hipótesis: los condicionamientos interpuestos por las cadenas de distribución?comercialización definen la dinámica de la agroindustria regional, con ello parte de las empresas industriales y productores primarios quiebran, son vaciados, abandonados (se destruye capital productivo local) o son absorbidos por otras empresas\/grupos accionarios de mayor envergadura. Sólo unos pocos se reinventan adaptándose a dichos condicionamientos.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243360,"idioma_id":4,"titulo":"RACK1 cooperates with NRAS(Q61K) to promote melanoma in vivo","resumen":"Melanoma is the deadliest skin cancer. RACK1 (Receptor for activated protein kinase C) protein was proposed as a biological marker of melanoma in human and domestic animal species harboring spontaneous melanomas. As a scaffold protein, RACK1 is able to coordinate the interaction of key signaling molecules implicated in both physiological cellular functions and tumorigenesis. A role for RACK1 in rewiring ERK and JNK signaling pathways in melanoma cell lines had been proposed. Here, we used a genetic approach to test this hypothesis in vivo in the mouse. We show that Rack1 knock-down in the mouse melanoma cell line B16 reduces invasiveness and induces cell differentiation. We have developed the first mouse model for RACK1 gain of function, Tyr::Rack1-HA transgenic mice, targeting RACK1 to melanocytes in vivo. RACK1 overexpression was not sufficient to initiate melanomas despite activated ERK and AKT. However, in a context of melanoma predisposition, RACK1 overexpression reduced latency and increased incidence and metastatic rate. In primary melanoma cells from Tyr::Rack1-HA, Tyr::NRasQ61K mice, activated JNK (c-Jun N-terminal kinase) and activated STAT3 (signal transducer and activator of transcription 3) acted as RACK1 oncogenic partners in tumoral progression. A sequential and coordinated activation of ERK, JNK and STAT3 with RACK1 is shown to accelerate aggressive melanoma development in vivo.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243362,"idioma_id":4,"titulo":"Large scale climate drivers for wind resource in Southern South America","resumen":"The relationship between the wind resource in Southern South America (SSA) and the Antarctic Oscillation (AAO) and El Niño\/Southern Oscillation (ENSO) is analyzed in this paper. Daily, monthly, seasonal and annual correlations were calculated between wind speeds at 50 m height derived from MERRA reanalysis and the indices of the mentioned climate drivers. Our results shows that the AAO exerts a significant control over wind speeds on inter annual and seasonal timescales. This relation is stronger during spring and summer, with negative correlations over northern Patagonia, the Argentine and Uruguayan Pampas and Paraguay. ENSO shows weaker relations with wind speeds, mainly on the monthly timescale, with negative correlations over Central Argentina; and during spring, with negative correlations over Southern Patagonia. The relations between AAO and wind speeds are relevant in the context of projected climate changes in the region over the next decades. ENSO might be used as a predictor of wind energy production over monthly and seasonal timescales (mainly during spring) in central Chile and Argentina, and Southern Patagonia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243363,"idioma_id":4,"titulo":"WIND RESOURCE ASSESSMENT IN THE RÍO NEGRO PROVINCE (PATAGONIA ARGENTINA) USING MERRA REANALYSIS","resumen":"Argentinean Patagonia presents a large potential for wind energy generation. Currently, despite of several projects being developed, there is no installed wind power at Río Negro province. In the present paper, we perform an assessment of the wind energy resource in the province, using wind data derived from MERRA (Modern Era Retrospective Analysis for Research and Applications) reanalysis. We compared time series, histograms and wind roses between wind data derived from MERRA and winddata observed at several meteorological stations finding, in general, good agreement between them. We fitted the hourly wind data to a Weibull distribution for each grid point of the MERRA dataset, and mapped the mean annual wind speed and Weibull k factor. We then computed the capacity factors for different wind generators. We identified several different spots with optimal parameters and closeness to existinginfrastructure (power lines and roads).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243370,"idioma_id":5,"titulo":"Transformaciones sociales y conocimiento en un contexto de crisis hídrica en la provincia de Córdoba, Argentina","resumen":"En el presente artículo analizoel lugar que ocupa el conocimiento en la producción de nuevasrelaciones sociales y configuraciones institucionales en el contextode una crisis hídrica en las sierras chicas de Córdoba, Argentina.Basándome en un abordaje etnográfico, analizo la manera en que lainformación (tanto de origen científico como no-científico) sobreciertos hechos y fenómenos relativos al estado de situación de lacrisis, oficia como conocimiento en  diferentes, pero complementariasmaneras: al ser, por un lado, apropiada y utilizada como base de lasestrategias de visibilización de diferentes agrupaciones yorganizaciones no gubernamentales; por otro lado, al ser fundamentode las intervenciones activas sobre la crisis por parte de estasagrupaciones, creando así relaciones de cohesión, pero también deconflicto. Mostraré cómo estas relaciones se imbrican en un procesode creación de nuevas configuraciones institucionales en el cual unacampaña electoral, las preocupaciones y acciones concretas de loshabitantes en torno al ambiente, y el conocimiento sobre los?procesos naturales?, entre otras dinámicas, son consideradascomo parte constitutiva de un proceso más general de producción dela sociedad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243373,"idioma_id":4,"titulo":"Using niche-modelling and species-specific cost analyses to determine a multispecies corridor in a  fragmented landscape","resumen":"Misiones, Argentina, contains the largest remaining tract of Upper Paraná Atlantic Forestecoregion; however, ~50% of native forest is unprotected and located in a mosaic of plantations,agriculture, and pastures. Existing protected areas are becoming increasingly isolateddue to ongoing habitat modification. These factors, combined with lower than expectedregional carnivore densities, emphasize the need to understand the effect of fragmentationon animal movement and connectivity between protected areas. Using detection dogs andgenetic analyses of scat, we collected data on jaguars (Panthera onca), pumas (Puma concolor),ocelots (Leopardus pardalis), oncillas (Leopardus tigrinus), and bush dogs (Speothosvenaticus) across habitats that varied in vegetation, disturbance, human proximity, and protectivestatus. With MaxEnt we evaluated habitat use, habitat suitability, and potential speciesrichness for the five carnivores across northern-central Misiones, Argentina. Through amultifaceted cost analysis that included unique requirements of each carnivore and varyingdegrees of overlap among them, we determined the optimal location for primary\/secondarycorridors that would link the northern-central zones of the Green Corridor in Misiones andidentified areas within these corridors needing priority management. A secondary analysis,comparing these multispecies corridors with the jaguar´s unique requirements, demonstratedthat this multispecies approach balanced the preferences of all five species andeffectively captured areas required by this highly restricted and endangered carnivore. Weemphasize the potential importance of expanding beyond a single umbrella or focal specieswhen developing biological corridors that aim to capture the varied ecological requirements  of coexisting species and ecological processes across the landscape. Detection dogs andgenetic analyses of scat allow data on multiple species to be collected efficiently across multiplehabitat types independent of the degree of legal protection. These data used with multifocalGIS analyses balance the varying degree of overlap and unique properties amongthem allowing for comprehensive conservation strategies to be developed relatively rapidly.Our comprehensive approach serves as a model to other regions faced with habitat lossand lack of data. The five carnivores focused on in our study have wide ranges, so theresults from this study can be expanded and combined with surrounding countries, withanalyses at the species or community level.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243376,"idioma_id":5,"titulo":"La tragedia 'Ortiz'","resumen":"Pasaron 75 años del fallecimiento del presidente Roberto M. Ortiz acaecido en julio de 1942. Durante dos días, miles de argentinos rindieron honores al Presidente que había renunciado tan solo un mes antes, pero que ya se encontraba mortalmente enfermo y en uso de licencia. La Nación, entre otros matutinos de envergadura y alcance nacional, rescataba en aquella oportunidad no sólo el 'don de multitud' del fallecido, sino su aptitud de 'viejo demócrata'. El senador Alfredo Palacios, en la Asamblea Legislativa, lo despedía como a uno de los 'paladines del civismo' en esa hora crítica del mundo. Pues Ortiz, durante su corto mandato (1938-1940), había dado señales claras de un programa institucional orientado al restablecimiento de la libertad electoral, en el marco de una década en la que el fraude imperó como norma.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243377,"idioma_id":4,"titulo":"Intraoperative Monitoring for Spinal Radiculomedullary Artery Aneurysm Occlusion Treatment: What, When and How Long?","resumen":"Background: Spinal radiculomedullary artery aneurysms are extremely rare. Treatment should be tailored to clinical presentation, distal aneurysm flow and lesion anatomical features. When a surgical occlusion is planned, it is necessary to evaluate whether intraoperative monitoring (IOM) should be considered or not as an indispensable tool to prevent potential spinal cord ischemia. Methods: We present a patient with symptoms and signs of spinal subarachnoid hemorrhage resulting from rupture of a T4 anterior radiculomedullary aneurysm, who underwent to an open surgical treatment under motor evoked potential (MEP) monitoring. Results: Due to the aneurysmal fusiform shape and the preserved distal flow, the afferent left anterior radiculomedullary artery was temporarily clipped, 2 minutes after the clamping the threshold stimulation level rose higher than 100 V and at minute 3, MEPs amplitude became attenuated over 50%. It This was considered as warning criteria to leave the vessel occlusion. The radiculomedullary aneurysm walls were reinforced, wrapped, with muscle and fibrin glue to prevent re-bleeding. The patient awoke from general anesthesia without focal neurologic deficit and made an uneventful recovery with complete resolution of her symptoms and signs. Conclusion: This paper attempts to build awareness of the possibility to cause or worsen a neurological deficit if a radiculomedullary aneurysm with preserved distal flow is clipped or embolized without an optimal IOM control. To our knowledge, MEP monitoring is an essential tool to prevent spinal cord ischemia.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243378,"idioma_id":4,"titulo":"Posterior interosseous neuropathy in polo riders A specific sport-related mononeuropathy","resumen":"Posterior interosseous neuropathy is an entrapment of the deep branch of the radial nerve in the forearm. The deep branch of the radial nerve is primarily a motor nerve, and compression of this nerve may lead to weakness in finger and thumb extension without sensory abnormalities. We present two cases of polo riders suffering of posterior interosseous neuropathy, confirmed both by electrodiagnostic testing and by surgical exploration in one case. We review the anatomic course and distribution of the posterior interosseous nerve, the clinical picture of its injury, and discuss the probable mechanism of entrapment in polo players.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243380,"idioma_id":5,"titulo":"Escuela y alumnado: (des)encuentros en la relación con el saber","resumen":"El siguiente artículo presenta la experiencia de campo y algunos resultados preliminaresde una investigación llevada a cabo en el marco del Proyecto de Investigación ?La constitución dela relación con el saber en los alumnos del último ciclo del nivel primario y primero del nivel medio?(Universidad Nacional del Comahue. Departamento de Psicopedagogía, 2015), desarrollado en elDepartamento Psicopedagogía del Centro Regional Zona Atlántica de la Universidad Nacional delComahue. En continuidad con estudios de las ciencias humanas que abordan la relación con el saberde los sujetos, y siguiendo los aportes teóricos de Charlot (2008), esta indagación se propuso analizar os procesos secundarios de constitución de la relación del alumnado con el saber, focalizando enalumnos y alumnas que culminan el nivel primario y que inician el nivel medio en escuelas públicasde la provincia de Río Negro. Identificando y problematizando, específicamente, los sentidos queeste alumnado otorga a los saberes escolares, y más en general, a la escuela y a sus trayectos en ella:pasados y futuros. La opción metodológica fue de carácter cualitativa, hermenéutico interpretativa.Se implementó un taller de acompañamiento psicopedagógico que consistió en distintos encuentros,desarrollados dentro del horario escolar, organizados, cada uno, en torno a un nudo problemáticoparticular y articulado a una actividad-producción que buscó recuperar el discurso del alumnado. Apartir de las producciones (escritas, orales, gráficas, dramáticas), se pesquisaron los objetos-saberesde los que se han apropiado, las actividades que saben dominar y formas relacionales aprehendidas,a través del análisis de las distintas dimensiones de la relación con el saber: en un primer momentola epistémica, y luego la social e identitaria. Como resultados, encontramos que el alumnado refirió adistintas figuras del aprender (Charlot, 2008), dando espacial relevancia a los modos de relacionarse.A su vez, desde la escuela, se enfatiza en la aprehensión del saber relacional pero como saberobjeto.Respecto al saber-escribir, se visualiza que su escritura sigue una normatividad diferente ala propuesta en la escuela, que podríamos denominar estándar. Finalmente, cuando aluden a loslugares en los que aprenden, si bien mencionan distintos espacios extraescolares y extrafamiliares, la","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243382,"idioma_id":4,"titulo":"Zoonotic Potential and Antibiotic Resistance of Escherichia coli in Neonatal Calves in Uruguay","resumen":"Escherichia coli is one of the main etiological agents of neonatal calf diarrhea (NCD). The objective of this study was toassess the presence of virulence genes, genetic diversity, and antibiotic resistance mechanisms in E. coli associated with NCDin Uruguay. PCR was used to assess the presence of intimin, Shiga-like toxin, and stable and labile enterotoxin genes.Resistance to fluoroquinolones and oxyimino-cephalosporins was estimated on Müller-Hinton agar plates. Further antibioticdisc-diffusion tests were performed to assess bacterial multi-resistance. The presence of PMQR, ESBL, MCR-1, and integrongenes was evaluated. Isolates were typed using ERIC-PCR, and 20 were selected for MLST, adhesion to Hep-2 cells, in vitrobiofilm formation, and eukaryotic cytotoxicity. The prevalence of ETEC genes was lower than 3% in each case (estA and elt).Six isolates were EPEC (eae+) and 2 were EHEC\/STEC (eae+\/stx1+). The results of a diversity analysis showed high geneticheterogenicity among isolates. Additionally, different sequence types, including ST10, ST21, and ST69, were assigned toselected isolates. Thirty-six percent (96\/264) of the isolates were fluoroquinolone-resistant, with 61\/96 (63.5%) beingmultidrug-resistant. Additionally, 6 were oxyimino-cephalosporin-resistant. The qnrB, qnrS1, and blaCTX-M-14 genes weredetected, whereas no isolates carried the mcr-1 gene. Isolates had the ability to adhere to Hep-2 cells and form biofilms. Only1 isolate expressed toxins in vitro. E. coli from NCD cases in Uruguay are very diverse, potentially virulent, and may interactwith eukaryotic cells. Zoonotic potential, together with resistance traits and the presence of horizontal transfer mechanisms,may play a significant role in infections caused by these microorganisms.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243383,"idioma_id":4,"titulo":"Variation in the Distribution of Putative Virulence and Colonization Factors in Shiga Toxin-Producing Escherichia coli Isolated from Different Categories of Cattle","resumen":"Shiga toxin-producing Escherichia coli (STEC) are pathogens of significant public healthconcern. Several studies have confirmed that cattle are the main reservoir of STEC inArgentina and other countries. Although Shiga toxins represent the primary virulencefactors of STEC, the adherence and colonization of the gut are also important in thepathogenesis of the bacteria. The aim of this study was to analyze and to compare thepresence of putative virulence factors codified in plasmid -katP, espP, subA, stcE- andadhesins involved in colonization of cattle -efa1, iha- in 255 native STEC strains isolatedfrom different categories of cattle from different production systems. The most prevalentgene in all strains was espP, and the less prevalent was stcE. katP was highly detectedin strains isolated from young and rearing calves (33.3%), while subA was predominantin those isolated from adults (71.21%). Strains from young calves showed the highestpercentage of efa1 (72.46%), while iha showed a high distribution in strains from rearingcalves and adults (87.04 and 98.48% respectively). It was observed that espP andiha were widely distributed throughout all strains, whereas katP, stcE, and efa1 weremore associated with the presence of eae and subA with the eae-negative strains. Agreat proportion of eae-negative strains were isolated from adults -dairy and grazingfarms- and fromrearing calves -dairy and feedlot-, whilemostly of the eae-positive strainswere isolated from dairy young calves. Data exposed indicate a correlation between thecategory of the animal and the production systems with the presence or absence ofseveral genes implicated in adherence and virulence of STEC.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243384,"idioma_id":5,"titulo":"Inhibitory capacity of Lactobacillus spp. against pathogens involved in foodborne diseases","resumen":"The genus Lactobacillus daily generates a growing interest among microbiologists and technologists, who try to discover new biotechnological applications and probiotic properties. The main goal of this study was to evaluate the inhibitory capacity of Lactobacillus spp. against pathogens (Escherichia coli O157:H7, Salmonella spp., Staphylococcus aureus) involved in foodborne diseases. For this purpose, samples were collected at different stages of the pork production chain. Seventy eight bacterial strains were isolated. Twenty seven (27) of these strains (37.18%) had genotypic and phenotypic characteristics corresponding to Lactobacillus spp. whereas 85.18% of them showed inhibitory capacity. These data showed that the studied strains represent a potential alternative to inactivate foodborne pathogens and thus provide safe food to consumers.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243386,"idioma_id":4,"titulo":"Patterns of phenotypic selection for oil and nectar in Monttea aphylla (Plantaginaceae) in a geographic mosaic of interactions with pollinators","resumen":"p { margin-bottom: 0.25cm; line-height: 120%; }Oil-flower speciesare highly specialized attracting a narrow group of oil-collectingbees in contrast to nectar-flower species visited by a wide diversityof pollinators. The vast majority of the oil species lack nectar as apollinator reward; this suggests that the ancestors of plants withoil flowers had either nectar-less flowers or faced strong selectionagainst the production of nectar once oil secretion evolved. Montteaaphylla is one of the few species that simultaneously offers oil andnectar in the same flower to pollinators. In particular, we studiedphenotypic selection in 16 populations in the Monte desert ofArgentina that spanned the entire geographical range of the species.In each population, we determined the relationship between plantpollination success and floral rewards. Positive directionalselection dif- ferentials were detected in three of the populations.One northern population favoured selection on oil production, twocentral or southern populations favoured selection on nectarproduction. Directional selection gradients were consistent with theabove results and correlational selection was significant for onenorthern population where pollination success was favoured by anincreased selection on oil and a decreased selection on nectar.Geographic variation in phenotypic selection models showedlatitudinal increase in directional selection on nectar. Geographicvariation in visitation frequencies of the specialist oil-collectingbee and relative abundance of other floral sources were related to anincrease in directional selection on nectar. Thus, evolution ofrewards appears to respond to a geographic mosaic where either oil ornectar are favoured in different contexts of ecologically specialisedoil collecting bees. Although phenotypic selection was detectable infew and was absent in most populations, the general pattern wasconsistent with current geographic differentiation in reward amounts.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243387,"idioma_id":4,"titulo":"Does hardness make flower love less promiscuous? Effect of biomechanical floral traits on visitation rates and pollination assemblages","resumen":"p { margin-bottom: 0.25cm; line-height: 120%; }Visitation rates andassemblage composition of pollinators have often been related toenvironmental, eco- logical and phenotypic variables. However, theinteraction between flowers and pollinators has not been evaluated ina biomechanical context. Floral rewards in keel flowers (Fabaceae,Faboideae) are concealed behind four joined petals, the keel-wingunit, and are accessible only if pol- linators open this unit byexerting force on it. Force needed to open the flower is expected toaffect the interaction with pollinators because pollinators mustinvest time and energy to open the keels. Consequently, plants withstiff flowers should be expected to experience diminished visitationfre- quency, particularly by weak visitors. To test this expecta-tion of diminished visitation rates and of assemblage com- positionbiased by pollinator strength, we measured the force needed to openthe keel flowers of five co-occurring legume species and, using acanonical correspondence analysis (CCA), we tested their associationwith pollinator visitation rates and assemblage composition. Weaddition- ally included a size flag variable in CCA to test theeffect of attractiveness on pollinator visits. There was noassociation between flower stiffness and visitation frequency.Accord- ing to the CCA, pollinator assemblage compositions wereassociated with the force needed to open the keel and not flag size.As a general pattern, weak flowers are pollinated by an unevenassemblage of weak bees while the stiffest lowers are pollinated byan even assemblage of large and strong bees. These results supportsthe idea that force has an effect in controlling pollinatorassemblage composition.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243388,"idioma_id":4,"titulo":"The long and the short of it: a global analysis of hawkmoth pollination niches and interaction networks","resumen":"Proboscis length has been proposed as a key dimension of plant pollination niches, but this niche space has not previously been explored at regional and global scales for any pollination system. Hawkmoths are ideal organisms for exploring pollinator niches as they are important pollinators in most of the biodiverse regions of the earth and vary greatly in proboscis length, with some species having the longest proboscides of all insects. Using data sets for nine biogeographical regions spanning the Old and New World, we ask whether it is possible to identify distinct hawkmoth pollination niches based on the frequency distribution of proboscis length, and whether these niches are reflected in the depths of flowers that are pollinated by hawkmoths. We also investigate the levels of specialization in hawkmoth pollination systems at the regional and community level using data from interaction network studies. We found that most regional hawkmoth assemblages have bimodal or multimodal distributions of proboscis length and that these are matched by similar distributions of floral tube lengths. Hawkmoths, particularly those with longer proboscides, are polyphagous and at the network level show foraging specialization equivalent to or less than that of bees and hummingbirds. In the case of plants, shorter-tubed flowers are usually visited by numerous hawkmoth species, while those that are longer-tubed tend to exclude shorter-proboscid hawkmoths and thus become ecologically specialized on longer-proboscid hawkmoth species. Longer-tubed flowers tend to have greater nectar rewards, and this promotes short-term constancy by long-proboscid hawkmoths. Our results show that pollinator proboscis length is a key niche axis for plants and can account for the patterns of evolution in functional traits such as floral tube length and nectar volume. We also highlight a paradoxical trend for nectar resource niche breadth to increase according to proboscis length of pollinators, while pollinator niche breadth decreases according to the tube length of flowers. A Lay Summary is available for this article.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243389,"idioma_id":4,"titulo":"Patterns and mechanisms in plant-pollinator interactions: Stefan Vogel's contribution to contemporary pollination biology","resumen":"The multidisciplinary field of pollination biology was enriched enormously by the contributions of Stefan Vogel (1925&ndash;2015). Vogel revived and expanded the pollination syndrome concept and recognized the importance of shifts between pollination modes for angiosperm diversification. He made a number of key discoveries, including perfume and oil reward systems in flowers and pollination of these flowers by highly specialized bees. He also contributed greatly to our understanding of floral mimicry, floral integration, and floral adaptations for bat pollination. Many of his insights were obtained through his field-based research in the tropics and his close ties to faculty and students at various universities in South America. Vogel´s work continues to be the inspiration for new scientific endeavours and this special issue of Flora about &ldquo;Patterns and mechanisms in plant-pollinator interactions&rdquo; contains a collection of 22 research papers that serve as a tribute to his legacy. The papers cover a wide range of topics and taxa, but can be broadly grouped into the themes of plant-pollinator interactions, functional morphology, floral rewards, floral signals and pollination syndromes, all of which also featured prominently in Vogel´s own work.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243390,"idioma_id":4,"titulo":"The long and the short of it: a global analysis of hawkmoth pollination niches and interaction networks","resumen":"Proboscis length has been proposed as a key dimension of plant pollination niches, but this niche space has not previously been explored at regional and global scales for any pollination system. Hawkmoths are ideal organisms for exploring pollinator niches as they are important pollinators in most of the biodiverse regions of the earth and vary greatly in proboscis length, with some species having the longest proboscides of all insects. Using data sets for nine biogeographical regions spanning the Old and New World, we ask whether it is possible to identify distinct hawkmoth pollination niches based on the frequency distribution of proboscis length, and whether these niches are reflected in the depths of flowers that are pollinated by hawkmoths. We also investigate the levels of specialization in hawkmoth pollination systems at the regional and community level using data from interaction network studies. We found that most regional hawkmoth assemblages have bimodal or multimodal distributions of proboscis length and that these are matched by similar distributions of floral tube lengths. Hawkmoths, particularly those with longer proboscides, are polyphagous and at the network level show foraging specialization equivalent to or less than that of bees and hummingbirds. In the case of plants, shorter-tubed flowers are usually visited by numerous hawkmoth species, while those that are longer-tubed tend to exclude shorter-proboscid hawkmoths and thus become ecologically specialized on longer-proboscid hawkmoth species. Longer-tubed flowers tend to have greater nectar rewards, and this promotes short-term constancy by long-proboscid hawkmoths. Our results show that pollinator proboscis length is a key niche axis for plants and can account for the patterns of evolution in functional traits such as floral tube length and nectar volume. We also highlight a paradoxical trend for nectar resource niche breadth to increase according to proboscis length of pollinators, while pollinator niche breadth decreases according to the tube length of flowers. A Lay Summary is available for this article.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243391,"idioma_id":4,"titulo":"Spin pumping and inverse spin Hall effect in antiferromagnetic exchange coupled [Co\/Ru\/Co]\/Pt heterostructures","resumen":"We report the observation of spin pumping and inverse spin Hall effects in antiferromagnetically coupled [Co\/Ru\/Co]\/Pt heterostructures. The &ldquo;spin-flop&rdquo; magnetization process observed in antiferromagnetically exchange coupled Co layers combined with spin pumping and inverse spin Hall effects allowed us to detect both transversal and longitudinal charge accumulations. By controlling the exchange coupling strength and the spin flop transition in the magnetization process, it was possible to produce spin currents polarized in different directions.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243392,"idioma_id":4,"titulo":"Magnetic coupling of stripe domains in FePt\/Ni 80 Fe 20 bilayers","resumen":"Equiatomic FePt in the A1 soft magnetic phase and Ni80Fe20 (permalloy) thin films form a stripe-like magnetic domain structure above a critical thickness. This critical thickness is considerably different in the two alloys and allows us to study the influence of the magnetic coupling in the domain configuration in bilayers. Using dc magnetron sputtering techniques, we fabricated two different sets of FePt\/Ni80Fe20 bilayers, keeping one thickness fixed and varying the other, and investigated the dc magnetic properties and the magnetic domain configuration of the structure. In all cases, magnetization reversal occurred at a single coercive field, indicating a relatively strong magnetic exchange coupling between both layers. The observed stripe period was also consistent with a model of spring magnet-like behavior. However, for certain values of FePt and permalloy thickness a complex nonparallel double stripe structure was found, which may be attributed to the influence of the dipolar stray field of the thicker layer on the stripe structure of the thinner film.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243393,"idioma_id":4,"titulo":"A recombinant iron transport protein from Bordetella pertussis confers protection against Bordetella parapertussis","resumen":"AbstractWhooping cough, which is caused by Bordetella pertussis and B. parapertussis, is a reemerging disease. New protective antigens are needed to improve the efficacy of current vaccines against both species. Using proteomic tools, it was here found that B. parapertussis expresses a homolog of AfuA, a previously reported new vaccine candidate against B. pertussis. It was found that this homolog, named AfuABpp , is expressed during B. parapertussis infection, exposed on the surface of the bacteria and recognized by specific antibodies induced by the recombinant AfuA cloned from B. pertussis (rAfuA). Importantly, the presence of the O-antigen, a molecule that has been found to shield surface antigens on B. parapertussis, showed no influence on antibody recognition of AfuABpp on the bacterial surface. The present study further showed that antibodies induced by immunization with the recombinant protein were able to opsonize B. parapertussis and promote bacterial uptake by neutrophils. Finally, it was shown that this antigen confers protection against B. parapertussis infection in a mouse model. Altogether, these results indicate that AfuA is a good vaccine candidate for acellular vaccines protective against both causative agents of whooping cough.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243396,"idioma_id":5,"titulo":"DINAMICA AMBIENTAL Y MATERIALES ARQUEOLÓGICOS DE LAS TERRAZAS FLUVIALES DEL RÍO EL BOLSÓN (DPTO. BELÉN, CATAMARCA). UNA APROXIMACIÓN TAFONÓMICA","resumen":"En este trabajo abordamos el estudio de los materiales arqueológicos líticos y cerámicos recuperados en la localidad de Villa Vil (Dpto. Belén, Catamarca) desde una perspectiva tafonómica. Buscamos contribuir al conocimiento de los procesos de formación de los depósitos arqueológicos del área, a partir de la identificación y evaluación de los efectos que provocaron estos procesos sobre materiales arqueológicos líticos y cerámicos. Los materiales analizados fueron recuperados en superficie y en perfiles expuestos en las terrazas aluviales del río El Bolsón, en la localidad de Villa Vil (Belén, Catamarca). En primer lugar, construimos un modelo de los eventos y procesos post-depositacionales que formaron los depósitos estudiados a partir de perfiles estratigráficos. Luego, siguiendo bibliografía para el tema, generamos protocolos de análisis basados en las características de los materiales recuperados y los agentes tafonómicos potencialmente involucrados en relación al modelo. Los datos obtenidos muestran que el conjunto de procesos que participaron en la conformación de los depósitos deben haber sido algo más complejos de lo que suponíamos inicialmente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243399,"idioma_id":4,"titulo":"Model of Long-Term Vitamin A Deficiency in the Mammary Gland of Virgin Rats","resumen":"Deficiency in vitamin A is an evil in underdeveloped countries where the minimum recommended intake is not achieved. This may have long-term implications on the health of the population. For this reason, it would be very useful to achieve an animal model where the different implications of this deficiency can be observed. This could lead to the formulation of future nutrition politics. The levels of retinoic acid and intermediary of the vitamin A pathway were studied; The levels of retinoic acid and intermediary of the vitamin A pathway (CRBP-1 and RAR&#945;) were studied. There was a decrease in the values of retinoic acid main indicator of deficiency of this vitamin in serum, liver and mammary gland and variation in expression of CRBP-1 and RAR&#945; mRNA in mammary gland. This model provides a tool for the study of the metabolism of vitamin A and its effects in different organs and especially in virgin mammary gland, where a deficiency is achieved despite being in a state of latency.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243401,"idioma_id":5,"titulo":"Hacia una primera tipología de los sistemas regionales de innovación en Argentina","resumen":"Los trabajos que han analizado las desigualdades socio-económicas entre las provincias argentinas no suelen tener en cuenta las diferencias provinciales en materia de conocimiento, innovación y aprendizaje. En paralelo, buena parte de la literatura sobre sistemas regionales de innovación se ha abocado a la construcción de tipologías empíricas que permitan abordar dichas diferencias, pero hasta ahora no se han aplicado ejercicios de esta naturaleza al caso argentino. Por medio de una combinación de técnicas multivariantes (análisis de componentes principales y análisis cluster) apuntamos a brindar un primer aporte en estos nichos de investigación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243404,"idioma_id":5,"titulo":"Desafíos para desarrollar una agroindustria local. Hacia una tipología de productores de cerveza artesanal en Bariloche","resumen":"La producción de cerveza artesanal en Bariloche viene experimentando un marcado dinamismo en los últimos años. En este artículo construimos una tipología de productores de cerveza artesanal de la ciudad para comprender no sólo la heterogeneidad de sus dinámicas productivas y comerciales sino especialmente los diversos problemas y desafíos que enfrentan. Aplicando la técnica de análisis cluster a datos relevados por medio de una encuesta, logramos identificar cuatro grupos con realidades y problemáticas bien diferentes, lo cual debiera tenerse en cuenta para facilitar la interacción interinstitucional, la transferencia de conocimientos y la adecuación de las políticas públicas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243411,"idioma_id":5,"titulo":"Determinación de cloro activo en diferentes soluciones de hipoclorito de sodio","resumen":"El hipoclorito de sodio, en sus diferentes concentraciones, constituye la primera elección como sustancia irrigadora de los conductos radiculares. Es por esto la importancia de mantener las concentraciones para obtener una buena desinfección El objetivo de este estudio fue determinar la cantidad de cloro activo presente en diferentes marcas comerciales de hipoclorito de sodio.Se seleccionaron diferentes marcas comerciales de hipoclorito de sodio, la evaluación del cloro activo se realizó mediante el método titulación de óxido-reducción. El 100% de las marcas comerciales no presentó la cantidad de cloro activo declarada por el fabricante (46,6 +\/15,68), en todas las muestras analizadas en laboratorio los resultados obtenidos fueron menores (39,57 +\/12,14) a los especificados por el fabricante con una diferencia estadísticamente significativa (p < 0.01)Esta investigación permite evaluar un aspecto relevante dentro del campo de la terapia endodóntica, mejorando los estándares de calidad de las prácticas clínicas.ABSTRACTSodium hypochlorite, at different concentrations, is the first choice as substance irrigating root canals. That is why the importance of maintaining concentrations to obtain good disinfection The aim of this study was to determine the amount of active chlorine in different brands of sodium hypochlorite. different brands of sodium hypochlorite were selected, evaluation of active chlorine was performed by redox method. The 100% trademarks not presented the amount of active chlorine declared by the manufacturer (46.6 + \/ 15.68) in all samples analyzed in the laboratory results obtained were lower (39.57 + \/ 12.14) to those specified by the manufacturer with a statistically significant difference (p <0.01). This research evaluates a relevant aspect within the field of endodontic therapy, improving the quality standards of clinical practice.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243412,"idioma_id":4,"titulo":"Towards Information Quality Assurance in Spanish Wikipedia","resumen":"Featured Articles (FA) are considered to be the best articles that Wikipedia has to offer and in the last years, researchers have found interesting to analyze whether and how they can be distinguished from ?ordinary? articles. Likewise, identifying what issues have to be enhanced or fixed in ordinary articles in order to improve their quality is a recent key research trend. Most of the approaches developed to face these information quality problems have been proposed for the English Wikipedia. However, few efforts have been accomplished in Spanish Wikipedia, despite being Spanish, one of the most spoken languages in the world by native speakers. In this respect, we present a breakdown of Spanish Wikipedia?s quality flaw structure. Besides, we carry out studies with three different corpora to automatically assess information quality in Spanish Wikipedia, where FA identification is evaluated as a binary classification task. Our evaluation on a unified setting allows to compare with the English version, the performance achieved by our approach on the Spanish version. The best results obtained show that FA identification in Spanish, can be performed with an F1 score of 0.88 using a document model consisting of only twenty six features and Support Vector Machine as classification algorithm.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243415,"idioma_id":5,"titulo":"Extracción de conocimiento con técnicas de minería de textos aplicadas a la psicología","resumen":"La extracción de conocimiento en bases de datos es un proceso complejo que en última instancia busca darle sentido a los datos. La minería de datos sólo constituye una etapa de este proceso cuyo objetivo consiste en la obtención de patrones y modelos aplicando métodos estadísticos y técnicas de aprendizaje automático. El presente artículo de revisión examina cómo pueden aplicarse las técnicas de minería de textos en el campo de la psicología. En este contexto, se describen los dos grandes propósitos de las técnicas de minería de textos: la descripción y la predicción. Finalmente, se destaca que la aplicación de técnicas de minería de textos en nuestra disciplina hace posible la medición o evaluación de distintos constructos psicológicos, a diferencia de la utilización de los tradicionales cuestionarios o encuestas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243416,"idioma_id":4,"titulo":"Evaluation of causal sentences in automated summaries","resumen":"This paper presents an experiment to show the importance of causal sentences in summaries. Presumably, causal sentences hold relevant information and thus summaries should contain them. We perform an experiment to refute or validate this hypothesis. We have selected 28 medical documents to extract and analyze causal and conditional sentences from medical texts. Once retrieved, classic metrics are used to determine the relevance of the causal content among all the sentences in the document and, so, to evaluate if they are important enough to make a better summary. Finally, a comparison table to explore the results is showed and some conclusions are outlined.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243417,"idioma_id":4,"titulo":"Simplifying credit scoring rules using LVQ + PSO","resumen":"One of the key elements in the banking industry relies on the appropriate selection of customers.To manage credit risk, banks dedicate special efforts to classify customers according to their risk. The usual decision-making process consists of gathering personal and financial information about the borrower.Processing this information can be time-consuming, and presents some difficulties because of the heterogeneous structure of data.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243418,"idioma_id":4,"titulo":"Document summarization using a scoring-based representation","resumen":"Currently, data repositories contain a plethora of information in different formats, most of which consists of text. This situation has raised interest in the study of techniques to automate the identification of the most relevant sentences of a document with the goal of generating a text summary. This article presents a technique for extracting the most representative sentences in a document, employing a user-defined criteria. The criteria is learned by the system using an optimization technique and a training document where the user has ranked the sentences according to their relevance. The proposed method has been applied to a five-chapter thesis with good results. At the end of this paper we provide some conclusions as well as ideas for future work.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243419,"idioma_id":4,"titulo":"Analysis of Methods for Generating Classification Rules Applicable to Credit Risk","resumen":"Credit risk is defined as the probability of loss due to non-compliance by the borrower with the required payments in relation to any type of debt. When financial institutions select their customers correctly, they can reduce their credit risk. To achieve this, they use various classification methodologies to sort customers based on their risk, analyzing a set of variables such as reputation, leverage, income and so forth. The extensive analysis and processing of these variables is quite time-consuming, partly because the data to be analyzed are not homogeneous. In this paper, we present an alternative method that operates on nominal and numeric attributes, which allows obtaining a predictive model that uses a reduced set of classification rules aimed at reducing credit risk. When the number of rules used decreases, credit analysts need less time to make their decisions, which will also result in better customer service. The methodology proposed here was applied to two databases of the UCI repository and two real databases of Ecuadorian banks that grant various types of credit. The results obtained have been satisfactory. Finally, our conclusions are discussed and future research lines are suggested.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243420,"idioma_id":4,"titulo":"Characterization of immune response in Staphylococcus aureus chronically infected bovine mammary glands during active involution","resumen":"The aim of this study was to characterize the immune response in Staphylococcus aureus chronically infected bovine mammary glands during active involution. Twenty-one Holstein non-pregnant cows in late lactation either uninfected or with chronic naturally acquired S. aureus intramammary infections (IMI) were included in this study. Cows were slaughtered at 7, 14 and 21 d after cessation of milking and samples for immunohistochemical analysis were taken. Protein expression of toll-like receptor 2 (TLR2) and TLR4 was significantly higher in S. aureus-infected quarters than in uninfected controls at the three involution stages studied. Protein expression of tumor necrosis factor-alpha (TNF-&#945;), interleukin (IL)-1&#945; and IL-17 was significantly affected by IMI; being higher in S. aureus-infected than uninfected quarters during all evaluated stages. In S. aureus-infected and uninfected quarters protein expression of lactoferrin increased from day 7?14 of involution, decreasing significantly to day 21 in mammary quarters with chronic infections. The number of monocytes-macrophages was significantly higher in S. aureus-infected than in uninfected control quarters at 7 and 21 d of involution. The number of T lymphocytes was significantly higher in S. aureus-infected than in uninfected quarters at 7 and 14 d of involution while the number of B lymphocytes was significantly higher in S. aureus-infected than in uninfected quarters during all evaluated stages, showing a progressive increase as involution advanced. These results demonstrated a sustained and exacerbated innate and adaptive immune response during chronic S. aureus IMI, playing a critical role in the infection control during active involution.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243421,"idioma_id":5,"titulo":"Valor agregado de los cultivos hortícolas tradicionales de General Pueyrredon, Argentina, en el período 1993-2010.","resumen":"Mar del Plata, ciudad cabecera del partido de General Pueyrredon, es el principal balneario turístico de Argentina y una importante ciudad del país en términos poblacionales. La producción de bienes y servicios finales del municipio, estimada a través del Producto Bruto Geográfico, indica que el turismo, el puerto pesquero y la industria alimenticia son las actividades económicas más relevantes del Partido. Sin embargo, la frutihorticultura intensiva es una importante fuente de valor agregado del sector primario local. En efecto, la zona cuenta con condiciones agroecológicas muy propicias que, junto con otros factores técnicos, mano de obra e insumos, hacen que esta región sea una de los principales centros de abastecimiento de hortalizas de hoja y fruto para el resto del país. Desde el 2001, cuando Argentina abandona el régimen cambiario de convertibilidad, los precios de los principales cultivos hortícolas experimentaron una aceleración relativamente menor que la de sus principales costos directos, presionando a los productores a generar cambios que permitieran mejorar sus resultados económicos de corto plazo. Sin embargo, la adopción de estrategias que incrementen el valor agregado sectorial requiere esquemas productivos de largo plazo y basados en acciones conjuntas entre productores. El objetivo del trabajo es analizar la evolución de los resultados económicos y las estrategias productivas adoptadas de los principales cultivos de huerta durante el período 1993-2010, desde la perspectiva de la estimación del valor agregado por esta actividad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243422,"idioma_id":4,"titulo":"Intramammary inoculation of Panax ginseng plays an immunoprotective role in Staphylococcus aureus infection in a murine model","resumen":"Theimmunoprotective effect of Panax ginseng(Pg) extract was investigated in a mouse mastitis model. Lactating female micewere intramammarily inoculated with Pg or placebo, and then were challengedwith S. aureus, while other group wasinoculated with S. aureus alone. Thenumber of bacteria recovered from mammary glands was significantly lower in Pg-treated S.aureus-infected mice (group I) compared with placebo-treatedS. aureus-infected mice (group II) and S.aureus-infected mice (group III). ThemRNA expression of TLR2, TLR4, IL-1a and TNF-a wasinfluenced by treatment; being the transcript levels for all genes higher ingroup I compared with group II and III. Activation of NF-kB and the number ofmonocytes-macrophages in mammary gland tissue was significantly increased ingroup I compared with group II and III. Pg extract was able to trigger an adequate immune response to confrontan infection demonstrating its protective effect and potential for preventingbovine intramammary infections.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243424,"idioma_id":4,"titulo":"Development and assessment of a new cage-like particle adjuvant","resumen":"OBJECTIVES:To obtain and assess stable cage-like particles with low surface charge density, which can be prepared using a standardized, economic and scalable method.METHODS:To form these nanoparticles, the lipid composition and proportion as well the method were modified in relation to cage-like particles previously described elsewhere. Bovine albumin was used to compare ISPA performance with that of other adjuvants in mice and to assess stability. Adjuvant efficacy was analysed using a mouse model of Trypanosoma cruzi infection, which shows protection against an intracellular infection that needs a strong cellular response.KEY FINDINGS:The new particles were better in terms of level, kinetics and profile of humoral responses than Freund Adjuvant, aluminium hydroxide and Montanide TM ISA 206; they also tended to improve ISCOMATRIX? performance. Particle size and adjuvant performance were conserved during the 6-month period assessed after preparation. In the model of Trypanosoma cruzi infection, mice immunized with ISPA and trans-sialidase developed high protection.CONCLUSIONS:The obtained nanoparticles were stable and outperformed the other assessed adjuvants in joining together the capacity of most adjuvants to enhance the immune response against specific antigen, to reduce the number of doses, to homogenize the response between individuals and to reach a balanced TH1\/TH2 response.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243425,"idioma_id":4,"titulo":"Characterization of immune response in Staphylococcus aureus chronically infected bovine mammary glands during active involution","resumen":"The aim of this study was to characterize the immune response in Staphylococcus aureus chronically infected bovine mammary glands during active involution. Twenty-one Holstein non-pregnant cows in late lactation either uninfected or with chronic naturally acquired S. aureus intramammary infections (IMI) were included in this study. Cows were slaughtered at 7, 14 and 21 d after cessation of milking and samples for immunohistochemical analysis were taken. Protein expression of toll-like receptor 2 (TLR2) and TLR4 was significantly higher in S. aureus-infected quarters than in uninfected controls at the three involution stages studied. Protein expression of tumor necrosis factor-alpha (TNF-&#945;), interleukin (IL)-1&#945; and IL-17 was significantly affected by IMI; being higher in S. aureus-infected than uninfected quarters during all evaluated stages. In S. aureus-infected and uninfected quarters protein expression of lactoferrin increased from day 7-14 of involution, decreasing significantly to day 21 in mammary quarters with chronic infections. The number of monocytes-macrophages was significantly higher in S. aureus-infected than in uninfected control quarters at 7 and 21 d of involution. The number of T lymphocytes was significantly higher in S. aureus-infected than in uninfected quarters at 7 and 14 d of involution while the number of B lymphocytes was significantly higher in S. aureus-infected than in uninfected quarters during all evaluated stages, showing a progressive increase as involution advanced. These results demonstrated a sustained and exacerbated innate and adaptive immune response during chronic S. aureus IMI, playing a critical role in the infection control during active involution.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243429,"idioma_id":4,"titulo":"Challenges of genomics in public health","resumen":"Public health systems have generally been based on an essentially biological model, with actions taking place in a fragmented way. These systems were founded on medical knowledge, which has focused on pathologies rather than on health status.At present, public health urgently requires the inclusion of the social determinants of health and the deep conjunctural and structural transformations that extend across contemporary societies. Some of these transformations are associated with demographic changes such as a fall of the fertility rate and decreased infant mortality, coupled with an increase in life expectancy. These characteristics have substantially modified the structure of the population pyramid, incorporating demographic changes that have a direct impact on public health at a global scale, as a result of the increase in chronic noncommunicable diseases and the presence of chronic co-morbidities. The epidemiological profile is also affected; in the Americas an increasing prevalence of chronic-degenerative diseases has been observed, in addition to the infectious diseases already present in the region","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243430,"idioma_id":5,"titulo":"La enseñanza de las categorías temporales en temas de Historia reciente. Un estudio de caso","resumen":"El siguiente artículo presenta resultados parciales de una investigación acerca de la enseñanza del tiempo histórico y las categorías temporales en temas de historia reciente, a partir de la aplicación de dos cuestionarios a estudiantes del profesorado de Historia de la Universidad Nacional del Litoral (Argentina). Se analizan las distintas definiciones y se establecen algunas hipótesis respectodel estado del conocimiento que tienen los alumnos de esta institución en el tiempo histórico y la historia reciente en la etapa preactiva de la enseñanza; y cuáles son los méritos y falencias del plan de estudios vigente, en el contexto de la formación inicial del profesorado.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243431,"idioma_id":5,"titulo":"Influence of heat stress on white blood cells in Holando Argentino cows","resumen":"The combination of high temperature and humidity, characteristic of the province of Santa Fe, the main dairy production area in Argentina, affects dairy production. The Temperature and Humidity Index (ITH) may be used as an indicator of heat stress. The aim of this investigation was to evaluate heat stress effects on white blood cells in response to the release of plasma cortisol in dairy bovines. The study was carried out in the Milking Parlor Module of the Facultad de Ciencias Agrarias, located at Zavalla (33º 1? S, 60º 53? O) during 2013-2014 period. Thirty Holando Argentino dairy cows from second and third lactation milking group were used. Samples were taken during spring (no heat waves) and summer (presence of heat waves) during morning and afternoon milkings. A radioimmunoassay method to dose cortisol was used (Coat-A-Count Cortisol, commercial kit), a blood cell counter (MINDRAY-BC 2800) was used to determine white blood cell total count, and May Grünwald Giemsa stain to determine neutrophil and lymphocyte count. An ITH increase during summer afternoons in coincidence with a significant increase of cortisol levels was observed, a relative decrease in lymphocyte count and an increase in neutrophil count were seen. The neutrophil\/lymphocyte ratio also showed a significant increase in summer. It is concluded that heat stress measured by ITH modifies the number and proportion of white blood cells and this could be attributed to plasma cortisol increase.Keywords: Heat stress; Cortisol; White blood cells.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243433,"idioma_id":5,"titulo":"Formación docente: una propuesta de trabajo colaborativo intercátedra","resumen":"El presente artículo se basa en el proyecto de investigación titulado Integración entre las Disciplinas y la Pedagogía. Enfoque superador en la Formación Docente, aprobado y subsidiado por la Secretaria de Ciencia, Técnica y Posgrado de la UNCuyo para el período 2013-2015. El proyecto propuso analizar y reflexionar acerca del desempeño de las practicantes de la Carrera de Profesorado de Grado Universitario en Lengua y Cultura Inglesas de la Facultad de Filosofía y Letras de la UNCuyo durante sus prácticas docentes, con un doble objetivo: revisar nuestras propias prácticas como formadoras y trabajar colaborativamente en la elaboración de intervenciones pedagógicas pertinentes. Estas intervenciones se concretaron a través de cuestionarios, los cuales fueron diseñados y analizados según el concepto de dispositivo. Este artículo contiene la fundamentación teórica de la propuesta, la descripción del dispositivo y los resultados del análisis de su implementación.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243434,"idioma_id":4,"titulo":"Physicochemical properties of ionic and non-ionic biocompatible hydrogels in water and cell culture conditions: Relation with type of morphologies of bovine fetal fibroblasts in contact with the surfaces","resumen":"Cationic, anionic and non-ionic hydrogels having acrylamide polymer backbones were synthesized via free radical polymerization with N,N-methylenebisacrylamide (BIS) as crosslinker. The chemical structures of the hydrogels were characterized by Fourier Transform Infrared Spectroscopy (FTIR). Physicochemical properties such as swelling kinetic, maximum swelling capacity, volume phase transition temperature (VPTT) and wettability (static water contact angle) of hydrogels swollen in aqueous and cell culture medium, at room and cell culture temperatures were studied. In order to correlate the surface properties of the hydrogels and cellular adhesivity of bovine fetal fibroblasts (BFFs), cellular behaviour was analyzed by inverted fluorescence optical microscopy and atomic force microscopy (AFM). MTT assay demonstrated that the number of viable cells in contact with hydrogels does not significantly change in comparison to a control surface. Flattened and spindle-shaped cells and cell spheroids were the adopted morphologies during first days of culture on different hydrogels. Cell spheroids were easily obtained during the first 5&nbsp;days of culture in contact with PNIPAM-co-20%HMA (poly (N-isopropylacrylamide-co-20%N-acryloyl-tris-(hydroxymethyl)aminomethane)) hydrogel surface. After 15&nbsp;days of culture all hydrogels showed high adhesion and visual proliferation. According to obtained results, non-ionic and hydrophilic surfaces with moderated wettability induce the formation of BFFs cell spheroids. These hydrogel surfaces could be used in clinical and biochemical treatments at laboratory level to cell growth and will allow generating the base for future biotechnologic platform","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243437,"idioma_id":4,"titulo":"The role of sex and mating status in the expansion process  of Arhopalus rusticus - an exotic cerambycid in Argentina","resumen":"In Córdoba province, central Argentina, there is an area of introduced pine trees. In 15 2006, an invading Cerambycid, Arhoplus rusticus, was detected in this region for the 16 first time. The species has since expanded its range until it now occupies the whole area.&nbsp; 17 A.&nbsp; rusticus&nbsp; is&nbsp; a&nbsp; common&nbsp; species&nbsp; of&nbsp; cerambycid&nbsp; in&nbsp; pine&nbsp; forests&nbsp; of&nbsp; the&nbsp; northern 18 hemisphere.&nbsp; In&nbsp; this&nbsp; paper,&nbsp; we&nbsp; analyze&nbsp; how&nbsp; sex&nbsp; and&nbsp; mating&nbsp; status&nbsp; affects&nbsp; flight 19 performance and the potential distribution of this species. The study was performed 20 with individuals collected from introduced pine forests in the center-west of Córdoba 21 Province (Argentina). The dispersal capability of Arhopalus rusticus was determined by 22 putting recently emerged mated and unmated individuals to fly in flight mills. Data of 23 pre-flight&nbsp; body&nbsp; weight,&nbsp; post-flight&nbsp; body&nbsp; weight,&nbsp; body&nbsp; length&nbsp; and&nbsp; elytron&nbsp; size&nbsp; were 24 obtained from the individuals that were put to fly. We found that females were bigger, 25 heavier, with longer elytra and were better flyers than males. We also found statistical 26 differences&nbsp; between&nbsp; dispersal&nbsp; potential&nbsp; depending&nbsp; on&nbsp; the&nbsp; mating&nbsp; status.&nbsp; Mated 27 individuals flew faster and longer distances than unmated ones, and also consumed a 28 smaller fraction of their body weight. A positive relationship was observed between 29 elytra size and flight speed. A map of males? and females? dispersal distances was 30 produced for the study region using the adjusted dispersal distance distribution of males 31 and females. The flight performance of males and females showed that, as females 32 disperse&nbsp; after&nbsp; copulation,&nbsp; they&nbsp; increase&nbsp; the&nbsp; chances&nbsp; of&nbsp; establishing&nbsp; the&nbsp; species&nbsp; in 33 unoccupied areas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243440,"idioma_id":4,"titulo":"The role of sex and mating status in the expansion process  of Arhopalus rusticus - an exotic cerambycid in Argentina","resumen":"In Córdoba province, central Argentina, there is an area of introduced pine trees. In 15 2006, an invading Cerambycid, Arhoplus rusticus, was detected in this region for the 16 first time. The species has since expanded its range until it now occupies the whole area.  17 A.  rusticus  is  a  common  species  of  cerambycid  in  pine  forests  of  the  northern 18 hemisphere.  In  this  paper,  we  analyze  how  sex  and  mating  status  affects  flight 19 performance and the potential distribution of this species. The study was performed 20 with individuals collected from introduced pine forests in the center-west of Córdoba 21 Province (Argentina). The dispersal capability of Arhopalus rusticus was determined by 22 putting recently emerged mated and unmated individuals to fly in flight mills. Data of 23 pre-flight  body  weight,  post-flight  body  weight,  body  length  and  elytron  size  were 24 obtained from the individuals that were put to fly. We found that females were bigger, 25 heavier, with longer elytra and were better flyers than males. We also found statistical 26 differences  between  dispersal  potential  depending  on  the  mating  status.  Mated 27 individuals flew faster and longer distances than unmated ones, and also consumed a 28 smaller fraction of their body weight. A positive relationship was observed between 29 elytra size and flight speed. A map of males? and females? dispersal distances was 30 produced for the study region using the adjusted dispersal distance distribution of males 31 and females. The flight performance of males and females showed that, as females 32 disperse  after  copulation,  they  increase  the  chances  of  establishing  the  species  in 33 unoccupied areas.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243443,"idioma_id":5,"titulo":"La expresión del lamento","resumen":"La poesía de Georg Trakl se sitúa en el contexto del movimiento expresionista. A esto puede sumarse el hecho de que Trakl es uno de los mayores innovadores de la poesía alemana, habiendo fallecido a comienzos de la Primera Guerra. Es la intención de este trabajo indagar a través del poema ?Lamento? (?Klage?), características que hacen a la obra expresionista, enmarcando esta propuesta en las consideraciones acerca de la oposición forma\/contenido y el modo en el que el expresionismo se vale de la materia artística.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243445,"idioma_id":5,"titulo":"LAS AVENTURAS DE ZAMBA. APUNTES SOBRE LA COMUNICACIÓN AUDIOVISUAL EN UN CANAL INFANTIL DEL MINISTERIO DE EDUCACIÓN ARGENTINO","resumen":"A partir del 2009 en la Argentina, en el marco de un proceso de democratización y desmonopolización de la comunicación audiovisual, se implementaron diversas políticas públicas destinadas a extender la participación en la producción de imágenes y relatos de todo el país. A partir del análisis de la relación entre ciertos aspectos estéticos del principal producto audiovisual de una señal infantil, dependiente del Ministerio de educación nacional, se examinan las tensiones existentes en la relación Estado \/ Mercado, que se traducen en representaciones y estéticas sobre la otredad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243448,"idioma_id":4,"titulo":"Manipulation of Mg2+- Ca2+ switch on the development of bone mimetic hydroxyapatite","resumen":"Ionic substitution can affect essential physico-chemical properties leading to a specific biological behavior upon implantation. Therefore, it has been proposed as a tool to increase the biological efficiency of calcium phosphate based materials. In the following study, we have evaluated the contribution of an important cation in nature, Mg2+, into the structure of previously studied biocompatible and biodegrad-able hydroxyapatite (HA) nanorods and its subsequent effect on its chemical, morphology, and bone mimetic articulation.Mg2+-substituted HA samples were synthesized by an aqueous wet-chemical precipitation method, followed by an hydrothermal treatment involving a Mg2+ precursor that partially replace Ca2+ ions into HA crystal lattice; Mg2+ concentrations were modulated to obtain a nominal composition similar to that exists in calcified tissues. Hydrothermally synthesized Mg2+-substituted HA nanoparticles were characterized by X-ray powder diffraction, FT-NIR and EDX spectroscopies, field emission scanning and high resolution transmission electron microscopies (FE-SEM, H-TEM). Molecular modeling combining ab initio methods and power diffraction data were also performed. Results showed that Mg2+-substitution promoted the formation of calcium deficient HA cdHA) where Mg2+ replacement is energetically favored at Ca(1) position in a limited and specific amount directing the  additional Mg2+ toward the surface of the crystal. The control of Mg2+ incorporation into HA nanorods gave rise to a tailored crystallinity degree, cell parameters, morphology, surface hydration, solubility, and degradation properties in a dose-replacement dependent manner. The obtained materials show qualities that conjugated together to drive an optimal in vitro cellular viability,spreading, and proliferation confirming their biocompatibility. In addition, an improved adhesion of osteoblast was evidenced after Mg2+&#8722;Ca2+ substitution.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243449,"idioma_id":4,"titulo":"Beneficial role of the phytoestrogen Genistein on vascular calcification","resumen":"Although soy phytoestrogen are proposed to prevent or improve postmenopausal vascular and bone diseases, the currently available data are controversial and unclear. In this study we evaluated the molecular and biochemical action of Genistein on the cellular events involved in vascular calcification. Rat monocytes, aortic vascular cell and osteoblasts cultures in vitro exposed to Gen were employed. Gen down regulated the expression of cell adhesion molecules involved in stable leukocyte attachment. Using flow cytometry we found that the PE significantly diminished monocyte integrins CD11b, CD11c and CD18 expression either under basal and pro-inflammatory environment. At endothelial level, Gen also reduced Intercellular Adhesion Molecule 1 mRNA expression. On vascular muscle cells, the PE markedly reduced cell proliferation and migration. When vascular calcification was studied, muscle cells transdifferentiation into osteoblasts like cells was evaluated. Cells were cultured in osteogenic medium for 21 days. The expression of alkaline phosphatase and the presence of calcified nodules in the extracellular matrix were selected as features of muscle transdifferentiation. Calcified muscle cells exhibited higher levels of alkaline phosphatase activity and enhanced deposition of calcium nodules respect to native cells. Both osteoblastic markers were significantly reduced after Gen treatment. In contrast to this anti-osteogenic action, on bone cells Gen promoted osteoblasts growth, enhanced alkaline phosphatase activity and increased matrix mineralization. Its mitogenic action on osteoblasts directly depends on nitric oxide endothelial production stimulated by the PE. The data presented suppose a beneficial role of Gen on bone and vascular cells, with a cross link between both systems","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243450,"idioma_id":4,"titulo":"What patients think about psychogenic nonepileptic seizures in Buenos Aires, Argentina: A qualitative approach","resumen":"Purpose: To analyse the methods of reasoning with regard to patients? experiences of living withpsychogenic nonepileptic seizures (PNES) in Buenos Aires, Argentina.Method: A qualitative approach using semi-structured interviews was used to gain an in-depth andcontextual understanding of the perspectives offive patients with PNES. Data collection and analysiswere followed by an inductive and interpretive approach informed by the principles of thematic analysis.Results: Explanatory models and prototypes were identified from the patients? narratives. Four patientsrelated their suffering regarding psychosocial causes ?family conflicts, sexual harassment, and lifechanges, among others-. Hereditary and organic hypotheses appeared to be unspecific. Folk explanationswere common to all participants (magic, witchcraft, energetic causes). Four patients used the termepilepsy as an illness prototype, focusing on seizures and the use of antiepileptic drugs. Three of them alsocompared their illness to other people?s ?attacks? (heart attacks, panic attacks, nervous breakdown). Onlyone of them referred to someone who was suspected of having epilepsy.Conclusion: Patients? psychosocial explanatory models are different from the results of previous studiesbecause these studies indicate that most patients support somatic explanations. Patients also use folkexplanations related to traditional medicine, which highlights the interpersonal aspects of the disease.Doctor-patient communication is essential for a correct understanding of PNES, resulting in betteroutcomes. It could also help to reduce the cultural distance between professionals and patients, leadingto narrowing inequalities present in multicultural healthcare services.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243451,"idioma_id":5,"titulo":"Una aproximación a la conceptualización que poseen los docentes respecto del fenómeno de cyberbullying","resumen":"El objetivo de este trabajo se orienta a indagar y describir las conceptualizaciones que docentes que ejercen su trabajo en escuelas de Educación Secundaria ubicadas en la Provincia de Buenos Aires (Argentina) poseen acerca del fenómeno de cyberbullying. A su vez, busca conocer y describir si dichos docentes cuentan con estrategias de intervención para abordar este fenómeno y su percepción acerca de la formación o capacitación para intervenir ante él. Mediante la realización de entrevistas semiestructuradas y el empleo de una metodología de enfoque cualitativo se construyeron categorías de análisis de la información recolectada. Los resultados hallados en este estudio sugieren la necesidad de brindar a los docentes información específica sobre la problemática, a fin de que puedan adquirir herramientas efectivas y contribuir con su adecuada prevención y abordaje.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243452,"idioma_id":4,"titulo":"Medium term in vitro conservation of two Argentinian oregano cultivars ? preliminary results of the effect of mannitol and sorbitol as growth retardants.","resumen":"The aim of this work was to develop an efficient protocol for mediumterm in vitro conservation of oregano. Two concentrations of mannitol andsorbitol (25 g.l-1 and 50 g.l-1) were tested to evaluate their effect as growthretardants over oregano plants belonging to Alpa Sumaj FCA  INTA and Aguanda FCA  INTA cultivars. Both cultivars are preserved in the in vitrocollection of oregano germplasm of the Laboratorio de Biotecnologia Vegetal(Facultad de Ciencias Agropecuarias - Universidad Nacional de Córdoba). Everysix weeks the length of major axis of plants (cm), fresh weight (g.plant-1) and dryweight (g.plant-1) were measured. At 24 weeks, plants were transferred to freshMS control medium (active growing medium) to evaluate the plants responsewhen mannitol and sorbitol were removed from the culture media. Regardless thecultivar, after 24 weeks of cultivation in slow growth conditions, best resultswere observed in plants growing in MS medium added with 25 g.l-1 of sorbitol;even though plants cultured on this medium were significantly smaller than those cultured on MS control medium, they showed a healthy appearance and whenthey were transferred to active growth medium its development was notsignificantly different from the control plants.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243453,"idioma_id":4,"titulo":"IL-2 is involved in immune response of prenatally stressed rats exposed to postnatally stimulation","resumen":"ABSTRACT. Environmental cues influence growth and development of mammals during prenatal and particularly early postnatallife and can exert long-lasting effects in adult life. High circulating concentration of glucocorticoids during pregnancy (prenatal stress)affects the activity of the hypothalamic-pituitary-adrenal axis (HPA) of offspring and has been linked to alter immune system responses.Early postnatal stimulation (handling) of prenatally stressed animals generates long-term beneficial effects on the reactiveness of theHPA axis and immune system function. The aim of this study was to further investigate the effect of handling on immune response inprenatally stressed male rats and to elucidate a possible relationship with the HPA axis activity. Control and prenatally stressed (PS)offspring by immobilization (IMO) were handled during the first week of life. Animals from both treatments were subjected to acutestress by IMO. Corticosterone (COR) plasma concentration was measured by RIA assay, T lymphocyte proliferation by [3H] thymidineassay and IL-2 levels by direct ELISA technique. Chronic IMO prenatal stress caused an increase in mother plasma COR basal levels.Furthermore, prenatally stressed rats subjected to an acute stress session had lower T cell proliferation and decreased IL-2 release. Inaddition, early postnatal stimulation reversed the negative effects of prenatal stress on proliferation of T lymphocytes and IL-2 release.Key words: early stimulation, prenatal stress, hypothalamic-pituitary-adrenal axis, immune system.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243455,"idioma_id":5,"titulo":"La hipótesis de la cinefilia docente. El cine de ficción en la escuela media argentina","resumen":"El artículo examina modos de incorporación pedagógica del cine de ficción por parte de docentes de escuelas argentinas de nivel medio, a partir de datos obtenidos en 'Escuelas, jóvenes y saberes: una investigación sobre las prácticas de docentes y estudiantes con el lenguaje audiovisual y los nuevos medios' (FLACSO\/Argentina, 2011). Se revisan prácticas con películas en el aula y supuestos acerca de las posibilidades pedagógicas de las imágenes, considerando tanto articulaciones y tensiones históricas de la relación entre escuela y cine como las particularidades del régimen visual actual. Finalmente, poniendo en relación hábitos de consumo y modos de utilización, se postula que cierto uso escolar de películas responde a un significativo vínculo personal de los docentes con el cine, una cinefilia docente.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243456,"idioma_id":4,"titulo":"Unidirectional freezing as a tool for tailoring air permeability in macroporous poly(ethylene glycol)-based crosslinked networks","resumen":"Unidirectional freezing followed by photopolymerization at sub-zero temperatures was used to obtain highly air-permeable monoliths with ordered porous structures. Scaffolds were obtained from aqueous solutions of a poly(ethylene glycol)dimethacrylate (PEGDMA) oligomer, a photosensitizer and a reducing agent. Solutions were vertically frozen in liquid nitrogen at a controlled rate to induce the oriented growth of ice crystals, and then cryo-photopolymerized under blue-light irradiation. Ice crystals were finally removed under vacuum producing macroporous hydrophilic networks with aligned pores. Porosities ranged between 80 % and 95 %, depending on the initial concentration of PEGDMA. The influence of processing variables on the final properties of the materials was addressed, concerning particularly the effect of porosity and freezing directionality on air permeability. Compared to porous PEGDMA-based monoliths with non-aligned macropores, gas permeability was two to three times higher for oriented scaffolds at the same porosity level, a fact explained by the easier transport of gas molecules through the aligned structures. However, the role of pore orientation on gas permeability was shown to be less marked as porosity increased. The results demonstrate that the use of unidirectional freezing strongly increases the permeability of monolithic samples up to values usually required, for instance, in tissue engineering applications (higher than 2 D). These findings provide new perspectives on pore design principles towards future scaffolding of polymeric crosslinked matrices.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243457,"idioma_id":5,"titulo":"Valor agregado de los cultivos hortícolas tradicionales de General Pueyrredon, Argentina, en el período 1993-2010","resumen":"Mar del Plata, ciudad cabecera del partido de General Pueyrredon, es el principal balneario turístico de Argentina y una importante ciudad del país en términos poblacionales. La producción de bienes y servicios finales del municipio, estimada a través del Producto Bruto Geográfico, indica que el turismo, el puerto pesquero y la industria alimenticia son las actividades económicas más relevantes del Partido. Sin embargo, la frutihorticultura intensiva es una importante fuente de valor agregado del sector primario local. En efecto, la zona cuenta con condiciones agroecológicas muy propicias que, junto con otros factores técnicos, mano de obra e insumos, hacen que esta región sea una de los principales centros de abastecimiento de hortalizas de hoja y fruto para el resto del país. Desde el 2001, cuando Argentina abandona el régimen cambiario de convertibilidad, los precios de los principales cultivos hortícolas experimentaron una aceleración relativamente menor que la de sus principales costos directos, presionando a los productores a generar cambios que permitieran mejorar sus resultados económicos de corto plazo. Sin embargo, la adopción de estrategias que incrementen el valor agregado sectorial requiere esquemas productivos de largo plazo y basados en acciones conjuntas entre productores. El objetivo del trabajo es analizar la evolución de los resultados económicos y las estrategias productivas adoptadas de los principales cultivos de huerta durante el período 1993-2010, desde la perspectiva de la estimación del valor agregado por esta actividad.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243458,"idioma_id":5,"titulo":"Modelo cualitativo de diagnóstico y mejora de gestión agropecuaria","resumen":"El trabajo forma parte un proyecto de investigación acreditado desde hace varios años en la Facultad de Agronomía, UNCPBA. La unidad de análisis para el trabajo son las empresas agropecuarias de la región de Azul provincia de Buenos Aires, aplicándose el denominado Modelo SER H4 de diagnóstico empresarial desde la perspectiva cualitativa y de consideración de intangibles (capacidad de gestión) como modelo innovador de utilización en la gestión empresarial.El trabajo persigue como objetivo general la aplicación y desarrollo  del Modelo SER H4. En su primera parte, plantea una breve descripción del Modelo SER H4 utilizado en el diagnóstico situacional y la mejora del desempeño integral de las empresas desde un enfoque sistémico y complementador de los actuales modelos de diagnóstico cuantitativo. En la segunda parte, se exponen los resultados de la aplicación del modelo a las empresas en estudio, describiendo la situación empresarial evidenciada y arribando a conclusiones.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243459,"idioma_id":5,"titulo":"ESTABLECIMIENTO IN VITRO DE CUATRO VARIEDADES DE OLIVO CULTIVADAS A CAMPO (Olea europea L)","resumen":"Plant sanitation through in vitro culture helps addressing sanity issues that affect production in olive (Olea europaea L.) groves. Our goal was to develop a protocol for in vitro establishment of plant material obtained from adult plants grown in field. We tested four methods of disinfection as well as response of the explants to the addition to medium of two cytokinins (BA, zeatin), two carbon sources (sucrose, mannitol), and activated charcoal, as well as the effect of the season in which materials were collected. The use of ultrasound during disinfection allowed satisfactory establishment rates (44%). BA improved sprouting (36% vs 24%), and so did mannitol (75% vs 20%). The addition of 1 g l-1 activated charcoal did not show statistically significative effects on both survival and sprouting. We observed differences among seasons of collection, by variety. Spring was ? for all varieties ? the most favourable time to collect explants: the highest sprouting rates (21% to 62%) and lowest levels of contamination were obtained - Frantoio and Manzanilla being the less affected varieties.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243460,"idioma_id":4,"titulo":"In vitro antitumor effects of AhR ligands Aminoflavone (AFP 464) and Benzothiazole (5F 203) on human renal carcinoma cells?","resumen":"We investigated activity and mechanism of action of two AhR ligand antitumor agents, AFP 464 and 5F 203 on human renal cancer cells, specifically examining their effects on cell cycle progression, apoptosis and migration. TK-10, SN12C, Caki-1 and ACHN human renal cancer cell lines were treated with AFP 464 and 5F 203. We evaluated cytotoxicity by MTS assays, cell cycle arrest and apoptosis by flow cytometry and corroborated a mechanism of action involving AhR signal transduction activation. Changes in migration properties by wound healing assays were investigated: 5F 203-sensitive cells show decreased migration after treatment, therefore we measured c-Met phosphorylation by Western blot in these cells. 5F 203 induced a decrease in cell viability which was more marked than AFP 464. This cytotoxicity was reduced after treatment with the AhR inhibitor &#945;-NF for both compounds indicating AhR signaling activation plays a role in the mechanism of action. 5F 203 is sequestered by TK-10 cells and induces CYP1A1 expression; 5F 203 potently inhibited migration of TK-10, Caki-1 and SN12C cells, and inhibited c-Met receptor phosphorylation in TK-10 cells. AhR ligand antitumor agents AFP 464 and 5F 203 represent potential new candidates for the treatment of renal cancer. 5F 203 only inhibited migration of sensitive cells and c-Met receptor phosphorylation in TK-10 cells. c-Met receptor signal transduction is important in migration and metastasis. Therefore, we consider that 5F 203 offers potential for the treatment of metastatic renal carcinoma.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243461,"idioma_id":4,"titulo":"The immune system as a new possible cell target for AFP 464 in a spontaneous mammary cancer mouse model","resumen":"Aminoflavone (AFP 464, NSC 710464), an antitumor agent which recently entered phase II clinical trials, acts against estrogen-positive breast cancer (ER+). AFP 464, which has a unique mechanism of action by activating aryl hydrocarbon receptor (AhR) signaling pathway, decreased tumor size and growth rate in the estrogen dependent, Tamoxifen-sensitive spontaneous M05 mouse model. Considering that AhR has recently emerged as a physiological regulator of the innate and adaptive immune responses, we investigated whether AFP 464 modulates the immune response in our mouse model. Studies on the effect of AFP 464 on the immune system were carried in BALB\/c mice bearing M05 semi-differentiated mammary adenocarcinomas that express estrogen and progesterone receptors. Splenic cells and tumor inflammatory infiltrates were studied by cytometric analyses. The modulation of splenocytes cytotoxic activity by AFP 464 was also evaluated. We further investigated the effects of AFP 464 on peritoneal macrophages by evaluating metalloproteinase, arginase and iNOS activities. We found that AFP 464 increased splenic cytotoxic activity, diminished the number of systemic and local Treg lymphocytes and MDSCs, and induced a M1 phenotype in peritoneal macrophages of M05 tumor bearing mice. Therefore, we conclude that AFP 464 modulates immune response which collaborates with its anti-tumor activity. Our results place the immune system as a novel target for this anti-cancer agent to strengthen the rationale for its inclusion in breast cancer treatment regimens. This article is protected by copyright. All rights reserved","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243465,"idioma_id":5,"titulo":"Los análisis de las intervenciones docentes en el marco del trabajo colaborativo entre investigadores y maestros como puente a la inclusión educativa","resumen":"A partir de un trabajo colaborativo entre docentes e investigadores en didáctica con el objeto de analizar prácticas de la enseñanza de la matemática desarrollado en el marco de nuestro proyecto de investigación, analizamos dos episodios con el propósito de relevar, a partir de las reflexiones sobre la enseñanza producidas en esos intercambios, los elementos que aportan a construir\/fortalecer\/sostener prácticas inclusivas respecto de la diversidad de conocimientos en la clase. El primer episodio toma como punto de partida la intervención de una maestra frente a las dificultades de un niño para abordar un problema de resta. La discusión en el espacio permite reconocer cuáles son los supuestos que dicha intervención tiene y, de esta manera, pensarla con un sentido más general que el  relativo al caso particular que se está tratando.  Nos interesa subrayar la potencialidad del espacio colaborativo para generalizar algunas de las intervenciones que hacen los docentes, sobre todo cuando se ofrecen como respuesta a procedimientos infantiles que llevan a  interpretar que los niños necesitan construir alguna relación particular para comprender las operaciones aritméticas que el problema implica. El juego entre la interpretación del docente sobre el procedimiento del alumno, el saber didáctico implícito en su intervención y consistente con su interpretación, la identificación de relaciones que los niños deben necesariamente construir para progresar en sus aprendizajes y la generalización de un tipo de intervención docente emergen como una producción del grupo colaborativo que contribuye a esclarecer las relaciones entre intervención docente vinculada a un conocimiento e inclusión educativa. El segundo episodio analiza la posibilidad del espacio colaborativo de precisar y enriquecer una estrategia didáctica puesta en juego por una de las maestras participantes, orientada a que los alumnos tengan mayor control de los resultados que proponen frente a los problemas aritméticos. Las reflexiones elaboradas dieron lugar al reconocimiento de alcances y límites de la estrategia elaborada.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243467,"idioma_id":4,"titulo":"Southern Central Andes Neogene magmatism over the Pampean Flat Slab: implications on crustal and slab melts contribution to magma generation in Precordillera, Western Argentina","resumen":"A Miocene to Pliocene (13 to 4.6 Ma) mostly pyroclastic sequence is exposed along the Iglesia Valley, tothe east of the former main volcanic arc. This area is a transitional region between Cordillera Frontal and Precordillera, over the f lat slab segment of the Southern Central Andes, at 29º30? S to 30º00? S. New radiometric ages, geochemical data, petrography and field relationships are evaluated to establish differences and similarities between Miocene arc related sequences across the main arc and its expansion towards a back arc position, in western Precordillera. Analyzed rocks have a magmatic arc signature partially like the former main volcanic arc to the west. The Iglesia Valley rocks are LREE-enriched (La\/Sm: 3.7-6.5) with respect to HREE (Sm\/Yb: 2.2-6.0) and define patterns with a pronouncedslope. Sm\/Yb ratios generally increase with time, as pressures increase, with retention of HREE in residual mineralogy, particularly garnet at Sm\/Yb&gt;4. Volcanic activity in Cordillera Frontal and the volcanic-volcaniclastic expression in Precordillera show a continuous increase in the La\/Yb ratio with decreasing age. Variations in the residual mineral phase equilibrating with magmas would be related to the progressive increase in crustal thickness due to the tectonic compressive regime resulting from shallow subduction since Middle Miocene. The data presented suggest that the arc magmatic activity during the Miocene was expanded notably to the East in relation to the location of the main arc at Valle del Cura, in Cordillera Frontal. The extensive amplitude of the volcanic arc activity is indicative of the slab gradual f lattening. Particularly, the mantle-derived magmas from Lomas del Campanario Formation (Western Precordillera) are enriched by subduction related f luids but also by crustal components. It is interpreted that the cause of the geochemical differences between the back arc position rocks and the main arc lay in the heterogeneous composition of the underlying continental crust involved in both locations. Presence of volcanic rocks with adakitic geochemical affinity probably reflect astenospheric-derived melts that interacted through a heterogeneous and thickened crust toward the surface.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243468,"idioma_id":5,"titulo":"La variación lingüística: panorama teórico didáctico en los lineamientos curriculares y libro escolares de lengua","resumen":"Este trabajo indaga, desde un plano analítico discursivo, el grado de correspondencia existente entre los marcos teóricos más representativos sobre la variación lingüística y las propuestas para su abordaje en los libros escolares de Lengua vigentes para la Educación Secundaria. Asimismo, se intenta establecer la adecuación\/ inadecuación entre tales propuestas y los lineamientos curriculares ministeriales. La problemática parte de una investigación aplicada a partir de un trabajo de sistematización de teorías basado en fuentes bibliográficas, y se cierra con una indagación empírica de tipo evaluativo. El análisis textual pondera el aporte de las Ciencias del lenguaje y organiza los resultados en una serie de categorías agrupadas según los enfoques pertinentes para el estudio de materiales pedagógicos y las conceptualizaciones destacadas sobre variación lingüística.  En suma, se trata de poner en cuestión la legibilidad y calidad de un corpus de libros escolares, a partir del estudio de la vinculación entre un concepto rector ?la variación lingüística?, los lineamientos curriculares y las propuestas para su abordaje.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243469,"idioma_id":5,"titulo":"Ese jard&iacute;n vedado al medio pelo. Cap&iacute;tulos del esnobismo en Victoria Ocampo, Adolfo Bioy Casares y Jorge Luis Borges","resumen":"Un acercamiento al esnobismo argentino resulta difícil de pensar sin dedicarle su capítulo al grupo reunido en torno a la revista Sur. Si el esnobismo se caracteriza como la imitación del deseo del otro, al mismo tiempo parece esencial asumir el esnobismo propio para poder criticarlo en otros. En este trabajo repasamos distintas manifestaciones al respecto, para concluir con un cuento donde Borges y Bioy Casares se acercan con humor corrosivo a un fenómeno que no les era ajeno.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243470,"idioma_id":5,"titulo":"BIOY Y SUS PRECURSORES LA TRADICI&Oacute;N DE LA CIENCIA FICCI&Oacute;N EN LA NARRATIVA DE ADOLFO BIOY CASARES","resumen":"Este artículo repasa la tradición de la ciencia ficción en Bioy Casares, pero concentrándose no tanto en los precursores abiertamente asumidos por el autor, sino más bien en la tradición francesa de la ciencia ficción, de Robida y Verne hasta Maurice Renard.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243472,"idioma_id":5,"titulo":"Las compensaciones económicas en la empresa familiar","resumen":"Analiza el impacto hacia el interior de una empresa familiar, del reclamo de compensaciones económicas por parte del cónyuge del familiar que se desempeña en la empresa","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243473,"idioma_id":5,"titulo":"Sua cuique persona. Retrato y vanguardia en la conformación de la autofición moderna","resumen":"A partir de la constatación de elementos de ficcionalización en el origen del retrato, así como su relación histórica con los escudos y las máscaras, encontramos del mismo modo en la autobiografía una prevalencia de elementos retóricos por encima de los referenciales. La vanguardia, al asumir lúdicamente estos hechos, sienta precedente para la moderna práctica de la autoficción. El hilo conductor a través de este recorrido es la alegoría, que veremos ejemplificada en dos autores argentinos: Macedonio Fernández y César Aira","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243474,"idioma_id":5,"titulo":"Las sociedades reguladas en la sección IV de la Ley General De sociedades o sociedades 'residuales'","resumen":"El artículo plantea un análisis completo del nuevo régimen legal de las sociedades 'Irregulares'","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243477,"idioma_id":4,"titulo":"An 18,000 year-long eruptive record from Volc&aacute;n Chait&eacute;n, northwestern Patagonia: Paleoenvironmental and hazard-assessment implications","resumen":"The 2008 eruption of Volcán Chaitén (VCha) in northwestern Patagonia was the first explosive rhyolitic eruption to have occurred within a century and provided an unprecedented scientific opportunity to examine all facets of the eruption ranging from magma rheology\/ascent rates to ash-fall effects on biota and infrastructure. Up to very recently it was thought that the latest eruption prior to the 2008 event occurred c. 9750 cal. a BP. Although a number of researchers have recognised additional eruptive products, but their stratigraphy, age, and geochemical attributes have not been systematically described and\/or recorded. In this study, we provide a detailed examination of andic cover-beds and tephra-bearing lake sequences located both proximally and distally to VCha, which record a series of hitherto unknown rhyolitic eruptive products and place all previous observations firmly within a coherent stratigraphic framework. Through major- and trace-element glass shard geochemistry we are able to confidently verify eruptive source. A total of 20 discrete tephra beds are recognised, with at least 10 having widespread areal distributions and\/or depositional imprints broadly comparable to, or greater than, the 2008-tephra event. This record indicates that VCha has been continuously but intermittently active as far back as the end of the Last Glacial Maximum (c. 18,000 cal a BP) with two dominant, genetically related magma types and an intermediary ?mixed? type. Before this the eruptive record has been largely obscured and\/or erased by widespread Andean piedmont glaciation. However, based on the tempo of VCha activity over the last c. 18,000 years, older VCha eruptives can be anticipated to occur as well as future hazardous explosive events. The new eruptive inventory will ultimately be useful for correlating equivalent-aged sequences and refining long-term eruptive tempo as well as corresponding temporal changes in magmatic evolution.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243478,"idioma_id":4,"titulo":"Stratigraphy, age and correlation of Lepu&eacute; Tephra: a widespread c. 11 000 cal a BP marker horizon sourced from the Chait&eacute;n Sector of southern Chile","resumen":"We describe the stratigraphy, age and correlation of a prominent tephra marker, named Lepué Tephra, extensively distributed in north-western Patagonia. Lepué Tephra is well dated at c. 11 000 cal a BP from numerous lake and soil cover-bed sequences and its recognition is useful for assessing the rate and timing of deglaciation as well as associated environmental changes in this region during the last glacial termination and early Holocene. Lepué Tephra has attributes typical of a complex and compositionally zoned phreatomagmatic eruptive. While the initial rhyolitic phase can be readily distinguished from multiple eruptive products sourced from the adjacent Volcán Chaitén, the main erupted end member is of basaltic?andesitic bulk composition &#8722; similar to younger tephras sourced from Holocene monogenetic cones adjacent to the Volcán Michimahuida massif (tMim). Lepué Tephra can be correlated to an equivalent-aged pyroclastic flow deposit (Amarillo Ignimbrite) prominently distributed in the south-eastern sector of tMim. The source vent for these co-eruptive events is obscured by an extensive ice field and is currently unknown. The widespread radially symmetrical distribution of Lepué Tephra centred on tMim cannot be attributed solely to volcanological considerations. Reduced Southern Hemisphere westerly wind influence interpreted from climate proxies at the time of eruption are also implicated. Copyright © 2017 John Wiley & Sons, Ltd.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243482,"idioma_id":5,"titulo":"Hongos agaricoides de los bosques de Nothofagus pumilio (Chubut, Argentina): Clave y listado de especies","resumen":"Se han realizado abundantes expediciones micológicas en Patagonia, pero los sitios relevados han cubierto solo una porción minima de esta extensa región. Así, las expediciones micológicas se centraron en los extremos norte (Neuquén y Rio Negro en Argentina, Santiago y Maule en Chile) y sur (Tierra del Fuego argentina y chilena) de los bosques subantárticos. El territorio comprendido entre estas provincias permanence inexplorado para los hongos agaricoides. El objetivo central de este trabajo fue evaluar la riqueza de especies de hongos agaricoides en bosques puros de Nothofagus pumilio (lenga) en Chubut (Argentina). Se realizaron 4 viajes de muestreo entre 2012 y 2014 en 3 bosques en la provincia del Chubut, Argentina. Se encontraron 130 especies de hongos agaricoides. Entre ellas, 125 pertenecen al orden Agaricales, 2 al orden Boletales y 3 al orden Russulales. La familia Cortinariaceae (Agaricales) fue la más rica, con 57 especies. Se presenta una clave para todas las especies halladas. Fueron encontrados 4 nuevos registros a nivel nacional y 124 a nivel provincial.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243484,"idioma_id":5,"titulo":"Calidad de aguas y análisis  de la contaminación  en el Río Tunuyán  Superior (Mendoza, Argentina)  en el periodo  2007-2014","resumen":"Desde agosto de 2007 a la fecha, se ha conformado una base de datos de calidad físico-química-microbiológica del agua de riego del río Tunuyán superior (Mendoza). Se seleccionaron seis sitios de muestreo, de lectura mensual, estratégicamente ubicados. Tres sitios pertenecientes al río: Dique Valle de Uco (VU), Costa Anzorena (CA) y Dique Tiburcio Benegas (TB) y otros tres a sus afluentes principales: río Las Tunas (LT) y arroyos Aguanda (A) y Yaucha (Y). Son objetivos del trabajo: (1) conformar una base de datos de parámetros físico-químicos y biológicos; (2) caracterizar al agua de la cuenca; (3) identificar las fuentes de contaminación de mayor impacto; (4) comparar la evolución temporal y espacial de la contaminación y (5) aportar pautas de gestión transferibles a la administración del recurso hídrico. Los parámetros analizados fueron: Temperatura (T), caudal (Q), salinidad (CE), relación de adsorción de sodio (RAS), nitratos (N03), fosfatos (P04), demanda química de oxígeno (DQO), oxígeno disuelto (OD), bacterias aerobias mesófilas (BAM) y coliformes fecales (CF). El trabajo presenta la variación espacial y temporal de los diferentes parámetros analizados que fueron sometidos a un análisis estadístico no paramétrico (Kruskal Wallis). Se observa que la CE arrojó valores bajos en los sitios LT, A e Y, y bastante más altos en VU, CA y TB, pudiendo comprobarse además una tendencia creciente en dichos sitios. Los valores de salinidad más elevados se encuentran en TB, seguidos por CA y VU. En estos tres sitios, los valores de RAS fueron también los más altos.  Con respecto al contenido de CF los sitios CA y TB superaron los valores máximos establecidos por la Resolución 778\/96 del Departamento General de Irrigación. Respecto a la evolución temporal, algunos parámetros presentaron diferencias significativas (&#945;<0,05).","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243485,"idioma_id":4,"titulo":"Scale-up of the production of soy (Glycine max L.) protein films using tape casting: Formulation of film-forming suspension and drying conditions","resumen":"The processing variables used to produce biopolymer films may have great influence on the material´s properties and production time. The aim of this work was to determine i) a suitable formulation (concentration and rheological properties) for tape casting  processing of soy protein suspensions ii) the effects of the drying method (heat conduction, C; and infrared radiation, IR) and temperature (40, 50 and 60ºC) on the drying kinetics and physical properties of resulting films. A soy protein isolate (SPI) concentration over 10.5% w\/v was required for proper tape casting processing. Conduction drying at 60 °C (C60) and IR60 showed short drying times and similar drying kinetics. However, drying by IR60 yielded films having poor mechanical properties. Raising the drying temperature increased film´s tensile strength, Young´s modulus, glass transition temperature (Tg), and heat seal strength. The results of this study demonstrated that it is possible to produce soy protein films at large scale by tape casting. The influence of the processing method and drying conditions on soy protein film properties are discussed.","palabras_clave":null},{"tipo_produccion_id":1,"anio_publica":2017,"producto_id":243486,"idioma_id":4,"titulo":"Short UV-C treatment inhibits polyphenoloxidase and prevents browning extending the shelf life of fresh-cut carambola (Averrhoa carambola L)","resumen":"In this work, we selected a short UV-C treatment for fresh-cut carambola and assessed its efficacy to supplement the benefits of low temperature storage. UV-C treated (6.0; 10.0 and 12.5 kJ m-2) carambola slices showed reduced deterioration compared to control fruit. Treatment with a dose of 12.5 kJ m-2UV-C were more effective to maintain maintenance and were selected for  subsequent experiments evaluating the combination of UV-C and refrigeration on fruit storability, physical, chemical and microbiological properties. Short UV-C exposure reduced weight loss and electrolyte leakage. UV-C treated carambola slices presented higher phenolic antioxidants than control after 21 d at 4 ºC and showed no alterations in soluble solids or titratable acidity. UV-C exposure also reduced the counts of molds, yeast and aerobic mesophilic bacteria. UV-C treated fruit showed a fresh-like appearance even after 21 d as oppose